Ranked Gene Set Pathway and Network Analysis
Peripheral Blood CD8+ T cell in Pre-Anti-PD-1 Antibody vs Post-Anti-PD-1 Antibody Treated Melanoma Patients
By Dong Hoon Han BCB420 2020
*References are at the bottom of the html!
# Install packages that are not there
install.packages(setdiff("tidyverse", rownames(installed.packages())))
library(tidyverse)
BiocManager::install(setdiff("GEOquery", rownames(installed.packages())), update = FALSE, version = "3.10")
library(GEOquery) # Bioconductor
packages = c("BiocManager", "knitr", "rlang",
"devtools", "reshape2", "kableExtra","circlize", "RCurl",
"png", "grid", "htmltools", "ggplot2", "cowplot",
"magick", "readxl", "GSA", "VennDiagram")
bioconductor_packages = c("edgeR", "biomaRt", "gprofiler2", "ComplexHeatmap", "HGNChelper")
BiocManager::install(setdiff(bioconductor_packages, rownames(installed.packages())), update = FALSE, version = "3.10")
install.packages(setdiff(packages, rownames(installed.packages())))
if(!("annotables" %in% rownames(installed.packages()))){
devtools::install_github("stephenturner/annotables")
}
# Load in all the packages
library(edgeR) # Bioconductor
library(knitr)
library(biomaRt) # Bioconductor
library(annotables) # this is from devtools
library(gprofiler2) # Bioconductor
library(reshape2)
library(kableExtra)
library(ComplexHeatmap) # Bioconductor
library(circlize)
library(HGNChelper)
library(RCurl)
library(png)
library(grid)
library(htmltools)
library(ggplot2)
library(cowplot)
library(magick)
library(readxl)
library(GSA)
library(VennDiagram)
# Loading in the Data
GSE96578 <- getGEO("GSE96578",GSEMatrix=FALSE)
Overall.Design <- data.frame(Overall.Design = GSE96578@header$overall_design)
Experiment.Summary <- data.frame(Experiment.Summary = GSE96578@header$summary)Preface to Pathway & Network Analysis
Intro
Raw Counts Matrix of GSE96578 was used in this analysis.
Brief Intro to What’s Been Done Up to Pathway & Network Analysis
This analysis aims to figure out the transcriptomic differences in the peripheral CD8 T cells between different treatment cycles and pre-treatment of the pembrolizumab, anti-PD1 mAb in melanoma patients. There were 4 treatment cycles and 3 patients’ blood sample has been taken in every treatment cycle.
After the raw counts matrix has been loaded in, it was subjected to filtering based on whether the feature has least 1 read per million in n of the samples, where n is the size of the smallest group of replicates. There were 3 biological replicates for this experiment (Experimental Conditions tab).
After filtering and converting the raw counts to counts per million, trimmed mean of m values, and log normalization, were applied (Normalization & ID Mapping tab). Identity mapping was subsequently done. Those ensembl gene ids not mapped HGNC symbols were all kept. External gene symbol column was added from HGNChelper package.
Differential gene expression analysis was performed using Limma-Trend and Negative Binomial Generalized Linear Models with Quasi-likelihood test from limma v3.40.6 and edgeR package v3.26.8. (Differential Gene & gProfiler tab)
Surprisingly, no individual genes met the threshold for statistical significance after multiple hypothesis testing correction between different treatment cycles.
However, around 160 genes were statistially significant between patient B and patient C.
Then, the differential gene lists were obtained without multiple hypothesis correction between treatment cycle 3 & pre-treatment, treatment cycle 4 & cycle 3, and patient B & patient C.
Thresholded overrepresentation analysis using gprofiler was done on the 3 genelists. No unifying biological themes were found in the cycle 4 vs cycle 3 or cycle 3 vs pre-treatment genelist.
Instead, the CD8 T cell related immune genesets popped up between patients B and C. More specifically, those genesets were enriched in patient C than patient B (Differential Gene & gProfiler tab). In conjunction with the heatmap result that cluster the genes associated patient B and C together (Differential Gene & gProfiler tab), this suggests the striking difference of patient C’s response to the drug compared to patient A & B’s responses.
You may now skip directly to Gene Set Enrichment Analysis (GSEA) section, or view more details about my pre-analysis on the tabs in the Preface section.
| Overall.Design |
|---|
| Transcriptional profiles of CD8+ T cells from peripheral blood of melanoma patients before and after anti-PD1 therapy |
# Loading in the Raw Counts Matrix
# Two count matrixes: normalized & raw counts, using the raw counts matrix
sfiles <- getGEOSuppFiles("GSE96578")
fnames = rownames(sfiles)
# [1] "/home/rstudio/GSE96578/GSE96578_AH_PBMC_RNAseq_normcounts.txt.gz"
# [2] "/home/rstudio/GSE96578/GSE96578_AH_PBMC_RNAseq_rawcounts.txt.gz"
# Loading in the raw count matrix
cd8_exp <-read.delim(fnames[2],header=TRUE, check.names = FALSE)
# Discarding that cycle2 sample
cd8_exp <- dplyr::select(.data = cd8_exp, -R_S418)
# Removing objects for sanity sake
rm( list = Filter( exists, c("sfiles", "fnames") ) )Summary Data Frame of the Samples Analyzed
##################################################################################
# What do each of these R_S4xx mean? i.e. what do each of these samples represent? ----
##################################################################################
sample.info.matrix <- data.frame()
# i under GSE96578@gsms is a GSE object, which can be probed using Meta() function
# Use for loop to probe each of the 13 samples
for(i in GSE96578@gsms){
sample.info.matrix <- rbind(sample.info.matrix,
data.frame(Meta(i)$title, Meta(i)$characteristics_ch1[3],Meta(i)$characteristics_ch1[1],
Meta(i)$characteristics_ch1[5], Meta(i)$library_strategy, Meta(i)$instrument_model))
}
colnames(sample.info.matrix) <- c("Title","Treatment", "Patient Age", "Disease State",
"Data Type", "Instrument")
# sample.info.matrix
# Decided not to include R_S418 Cycle2 treatment in the downstream analysis, because
# there is no replicate for this Cycle2 treatment RNA-seq experiment
sample.info.matrix <- sample.info.matrix[-3,]
# head(sample.info.matrix)
# head(cd8_exp)
# Let's create a more descriptive label for each of the samples
descriptive.label <- c("pt.A.PreTreat", "pt.A.Cycle1", "pt.A.Cycle3", "pt.A.Cycle4",
"pt.B.PreTreat", "pt.B.Cycle1", "pt.B.Cycle3", "pt.B.Cycle4",
"pt.C.PreTreat", "pt.C.Cycle1", "pt.C.Cycle3", "pt.C.Cycle4")
sample.info.matrix %>% mutate(Label = descriptive.label) -> sample.info.matrix
sample.info.matrix %>%
mutate(Patient = stringr::str_match(string = sample.info.matrix$Label,
pattern = "(?<=\\.)(.*)(?=\\.)")[,1]) %>%
mutate(Treatment = stringr::str_match(string = sample.info.matrix$Label,
pattern = "(?<=pt\\.[A-z]\\.)(.*)")[,1]) -> sample.info.matrix
# Lets change the Count Matrix Sample names to the more descriptive names as well
colnames(cd8_exp)[4:15] <- sample.info.matrix$Label
# Removing descriptive.label for sanity sake
rm( list = Filter( exists, c("descriptive.label", "i") ) )
kable(sample.info.matrix) %>%
kable_styling(bootstrap_options = "striped", full_width = F)| Title | Treatment | Patient Age | Disease State | Data Type | Instrument | Label | Patient |
|---|---|---|---|---|---|---|---|
| R_S416 | PreTreat | age: 81 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.A.PreTreat | A |
| R_S417 | Cycle1 | age: 81 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.A.Cycle1 | A |
| R_S419 | Cycle3 | age: 81 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.A.Cycle3 | A |
| R_S420 | Cycle4 | age: 81 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.A.Cycle4 | A |
| R_S426 | PreTreat | age: 71 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.B.PreTreat | B |
| R_S427 | Cycle1 | age: 71 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.B.Cycle1 | B |
| R_S428 | Cycle3 | age: 71 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.B.Cycle3 | B |
| R_S429 | Cycle4 | age: 71 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.B.Cycle4 | B |
| R_S430 | PreTreat | age: 67 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.C.PreTreat | C |
| R_S431 | Cycle1 | age: 67 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.C.Cycle1 | C |
| R_S432 | Cycle3 | age: 67 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.C.Cycle3 | C |
| R_S433 | Cycle4 | age: 67 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.C.Cycle4 | C |
Experimental conditions
Patients with stage IV melanoma were enrolled for treatment with pembrolizumab (pembro), anti-PD-1 antibody (2 mg kg^-1 by infusion every 3 weeks). After receiving their consents, peripheral blood was obtained before treatment and before each pembro infusion every weeks for 12 weeks. (Huang et al. 2017)
For RNA sequencing experiments, total CD8 T cells were sorted using a dump/dead-CD3+ CD8+ gating strategy, by BD Aria Sorter (Huang et al. 2017). Dump here means the exclusion channel which is used for staining everything you do not want.
So the controls are the RNA sequencing of total CD8 T cells before pembro infusion.
The tests are the RNA sequencing of total CD8 T cells 3 weeks after each pembro infusion.
Overall the samples are divided into cycle 1, 2, 3, 4, as pembro was injected at Week 0, 3, 6, 9, and the blood was drawn before pembro injection at Week 0, 3, 6, 9, 12.
Pretreatment samples are week 0 pre-treatment peripheral blood CD8 T cells. These are the controls.
Cycle 1 samples are week 3 peripheral blood CD8 T cells after the week 0 pembro injection.
Cycle 2 samples are week 6 peripheral blood CD8 T cells after the week 0, 3 pembro injection.
Cycle 3 samples are week 9 peripheral blood CD8 T cells after the week 0, 3, 6 pembro injection.
Cycle 4 samples are week 12 peripheral blood CD8 T cells after the week 0, 3, 6, 9 pembro injection.
Cycle 2 samples were not included in this analysis, because other samples all had 3 replicates (from 3 patients) whereas there was only one cycle 2 sample (from a single patient).
Comprehensive Sample Information Matrix -> Not including R_S418 Cycle2 treatment in the downstream analysis, because there is no biological replicate for this Cycle2 treatment RNA-seq experiment
| Title | Treatment | Patient Age | Disease State | Data Type | Instrument | Label | Patient |
|---|---|---|---|---|---|---|---|
| R_S416 | PreTreat | age: 81 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.A.PreTreat | A |
| R_S417 | Cycle1 | age: 81 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.A.Cycle1 | A |
| R_S419 | Cycle3 | age: 81 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.A.Cycle3 | A |
| R_S420 | Cycle4 | age: 81 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.A.Cycle4 | A |
| R_S426 | PreTreat | age: 71 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.B.PreTreat | B |
| R_S427 | Cycle1 | age: 71 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.B.Cycle1 | B |
| R_S428 | Cycle3 | age: 71 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.B.Cycle3 | B |
| R_S429 | Cycle4 | age: 71 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.B.Cycle4 | B |
| R_S430 | PreTreat | age: 67 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.C.PreTreat | C |
| R_S431 | Cycle1 | age: 67 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.C.Cycle1 | C |
| R_S432 | Cycle3 | age: 67 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.C.Cycle3 | C |
| R_S433 | Cycle4 | age: 67 | disease state: melanoma patient | RNA-Seq | Illumina NextSeq 500 | pt.C.Cycle4 | C |
GPL.frame <- data.frame(GPL.Title = current_gpl_info$title, Submission = current_gpl_info$submission_date,
Last.Update = current_gpl_info$last_update_date,
Organism = current_gpl_info$organism, Number.of.Series = length(current_gpl_info$series_id),
Number.of.Samples = length(current_gpl_info$sample_id) )
kable(Experiment.Summary)| Experiment.Summary |
|---|
| RNA-Seq analysis was used to study the profile of CD8 t cells from melanoma patients before and after treatment to understand if we can detect transcriptional changes in peripheral blood |
| GPL.Title | Submission | Last.Update | Organism | Number.of.Series | Number.of.Samples |
|---|---|---|---|---|---|
| illumina NextSeq 500 (Homo sapiens) | Mar 14 2017 | Mar 14 2017 | Homo sapiens | 1 | 13 |
Data Processing Protocol for all Samples from Fastq to Raw Counts
j = 0
Data_Processing <- list()
Extraction_Protocol <- list()
for(i in GSE96578@gsms){
j = j + 1
Data_Processing[[j]] <- Meta(i)$data_processing
Extraction_Protocol[[j]] <- Meta(i)$extract_protocol_ch1
}
unlist(unique(Data_Processing))## [1] "The fastqs were aligned using STAR 2.5.2a and hg19" "The aligned files were processed using PORT gene-based normalization ( https://github.com/itmat/Normalization )" "The differential gene expression was done with limma" "Genome_build: hg19" "Supplementary_files_format_and_content: Raw counts and normalized counts"# [[1]]
# [1] "The fastqs were aligned using STAR 2.5.2a and hg19"
# [2] "The aligned files were processed using PORT gene-based normalization
# ( https://github.com/itmat/Normalization )"
# [3] "The differential gene expression was done with limma"
# [4] "Genome_build: hg19"
# [5] "Supplementary_files_format_and_content: Raw counts and normalized counts" Extraction Protocol for all Samples
## [1] "RNA was isolated using the Qiagen RNeasy micro kit (#74034) according to the manufacturer's protocol" "RNA-seq libraries were prepared using the SMARTer Stranded Total RNA-Seq Kit for Pico Input Mammalian from Clonetech according to the manufacturer's protocol (#635007)" "The libraries were sequenced on an Illumina NextSeq machine using a 300 cycle high output flow cell (#15057929)"# [[1]]
# [1] "RNA was isolated using the Qiagen RNeasy micro kit (#74034) according to the manufacturer's
# protocol"
# [2] "RNA-seq libraries were prepared using the SMARTer Stranded Total RNA-Seq Kit for Pico Input Mammalian
# from Clonetech according to the manufacturer's protocol (#635007)"
# [3] "The libraries were sequenced on an Illumina NextSeq machine using a 300 cycle high output
# flow cell (#15057929)"
# Removing j, i, Data_Processing, & Extraction_Protocol
rm(i, j, Data_Processing, Extraction_Protocol)Normalization & ID Mapping
Dimension of the Raw Counts Matrix
## [1] 28383 15There are 28383 features (i.e. genes/nongenes) & 12 out of 15 columns are samples; other 3 are ID, gene coordinate, gene symbol.
This raw count matrix consists of 4 triplet replicates so 12 samples in total: Pre-treatment, Cycle 1, Cycle 3, Cycle 4
# head(cd8_exp)
# Create a table of row counts for each factor (i.e. gene name or maybe sth else) in the geneSymbol column
summarized_gene_counts <- sort(table(cd8_exp$geneSymbol),decreasing = TRUE)Filtering out weakly expressed and noninformative (non-aligned) features, all of which were done in edgeR
cpms <- cpm(cd8_exp[,4:15])
rownames(cpms) <- cd8_exp[,1]
# Filtering out low counts
keep <- rowSums(cpms >1) >=3 # So n is 3 here, and all features must have 1 read per million in 3 of the samples
cd8_exp_filtered <- cd8_exp[keep, ]
# dim(cd8_exp) # [1] 28383 15
# dim(cd8_exp_filtered) # [1] 17118 15
before_after <- t(data.frame(Before = dim(cd8_exp), After = dim(cd8_exp_filtered)))
colnames(before_after) <- c("Number of Features", "Number of Columns")
# Did this solve the duplicate issue?
summarized_gene_counts_filtered <- sort(table(cd8_exp_filtered$geneSymbol),decreasing = TRUE)
kable(before_after) %>%
kable_styling(bootstrap_options = "striped", full_width = F)| Number of Features | Number of Columns | |
|---|---|---|
| Before | 28383 | 15 |
| After | 17118 | 15 |
Genes with very low count across all libraries provide very little evidence for differential expression. Moreover, the discreteness of these low counts interferes with some of the statistical approximations used in edgeR package (M D Robinson, McCarthy, and Smyth 2010).
The genes were filtered with count-per-million (CPM) rather than raw counts, as raw counts do not account for differences in library sizes between samples(M D Robinson, McCarthy, and Smyth 2010).
\(CPM_{i} = \frac{X_{i}}{N}\cdot 10^{6}\)
Here \(X_{i}\) is the count for certain gene and \(\frac{N}{10^{6}}\) is the number of fragments you sequenced in the library per million.
By processing the raw count to counts per million, the library size differences between samples can be accounted for.
# Removing Data for Sanity Sake
rm( list = Filter( exists, c("keep", "summarized_gene_counts_filtered", "cpms", "summarized_gene_counts") ) )TMM Normalization
Normalization is a necessary step to adjust the data so that we can focus more on biological variation than technical variation.
TMM between each pair of samples are used to calculate the scale factors for each library size that minimize log fold changes between the samples for most genes.
The product of the library size and the scaling factor is called effective library size, which replaces the original library size in all downstream analysis.(Mark D Robinson and Oshlack 2010)
##################################################################################
# Normalization - First step in Analysis ----
##################################################################################
# We want to look a biological variation rather than technical variation
# Our sampling of data will form certain distribution like normal, bimodal, poisson, power log (all are well characterized)
# or some other distributions
# Boxplot of each of the samples
cd8_data2plot <- log2(cpm(cd8_exp_filtered[,4:15]))
# Log2 transformation of the cpm of the new filtered expression data
cd8_exp_filtered_cpm_log2 <- log2(cpm(cd8_exp_filtered[,4:15]))
# Trimmed Mean - is the average after removing the upper and lower percentage of the data points
# 30% of the M values and 5% of the A values by default
# Application of TMM to the dataset
# Creating an edgeR container for RNAseq count data
filtered_data_matrix <- as.matrix(cd8_exp_filtered[,4:15])
rownames(filtered_data_matrix) <- cd8_exp_filtered$id
# colnames(cd8_exp_filtered)[4:15]
# Creating DGElist object from the filtered expression matrix
# Here, group parameter is a vector/factor that gives the experimental group/condition for each sample/library
# For this dataset, it is the different cycles of Anti-PD-1 antibody treatment to the melanoma patients
TreatmentType <- sample.info.matrix$Treatment
names(TreatmentType) <- sample.info.matrix$Title
# TreatmentType
dGEList.for.TMM <- DGEList(counts=filtered_data_matrix, group= TreatmentType)
# Removing TreatmentType, filtered_data_matrix
rm(TreatmentType, filtered_data_matrix)
# edgeRUsersGuide()
# The calcNormFactors function normalizes for RNA composition by finding a set of scaling
# factors for the library sizes that minimize the log-fold changes between the samples for most
# genes. The default method for computing these scale factors uses a trimmed mean of M-
# values (TMM) between each pair of samples [30]
# Robinson, M.D. and Oshlack, A. (2010). A scaling normalization method for
# differential expression analysis of RNA-seq data. Genome Biology 11, R25.
# We call the product of the original library
# size and the scaling factor the effective library size. The effective library size replaces the
# original library size in all downsteam analyses.
dGEList.for.TMM <- calcNormFactors(dGEList.for.TMM)
# str(dGEList.for.TMM)Side to Side Boxplot of Before & After TMM
# Getting the normalized data
normalized_counts <- cpm(dGEList.for.TMM, log = TRUE) # When log is TRUE, it returns log2 values.
# Side to Side Boxplot Before and After TMM
par(mfrow=c(1,2))
cd8_data2plot <- log2(cpm(cd8_exp_filtered[,4:15]))
boxplot(cd8_data2plot, xlab = "Samples", ylab = "log2 CPM",
las = 2, cex = 0.5, cex.lab = 0.5,
cex.axis = 0.5, main = "CD8+ T Samples")## Warning in bplt(at[i], wid = width[i], stats = z$stats[, i], out = z$out[z$group == : Outlier (-Inf) in boxplot 1 is not drawn## Warning in bplt(at[i], wid = width[i], stats = z$stats[, i], out = z$out[z$group == : Outlier (-Inf) in boxplot 2 is not drawn## Warning in bplt(at[i], wid = width[i], stats = z$stats[, i], out = z$out[z$group == : Outlier (-Inf) in boxplot 3 is not drawn## Warning in bplt(at[i], wid = width[i], stats = z$stats[, i], out = z$out[z$group == : Outlier (-Inf) in boxplot 4 is not drawn## Warning in bplt(at[i], wid = width[i], stats = z$stats[, i], out = z$out[z$group == : Outlier (-Inf) in boxplot 5 is not drawn## Warning in bplt(at[i], wid = width[i], stats = z$stats[, i], out = z$out[z$group == : Outlier (-Inf) in boxplot 6 is not drawn## Warning in bplt(at[i], wid = width[i], stats = z$stats[, i], out = z$out[z$group == : Outlier (-Inf) in boxplot 7 is not drawn## Warning in bplt(at[i], wid = width[i], stats = z$stats[, i], out = z$out[z$group == : Outlier (-Inf) in boxplot 8 is not drawn## Warning in bplt(at[i], wid = width[i], stats = z$stats[, i], out = z$out[z$group == : Outlier (-Inf) in boxplot 9 is not drawn## Warning in bplt(at[i], wid = width[i], stats = z$stats[, i], out = z$out[z$group == : Outlier (-Inf) in boxplot 10 is not drawn## Warning in bplt(at[i], wid = width[i], stats = z$stats[, i], out = z$out[z$group == : Outlier (-Inf) in boxplot 11 is not drawn## Warning in bplt(at[i], wid = width[i], stats = z$stats[, i], out = z$out[z$group == : Outlier (-Inf) in boxplot 12 is not drawn# Adding a median line at each boxplot (median of the medians of each sample)
abline(h = median(apply(cd8_data2plot, 2, median)), col = "green", lwd = 0.6, lty = "dashed")
d_data2plot <- normalized_counts
boxplot(d_data2plot, xlab = "Samples", ylab = "log2 CPM",
las = 2, cex = 0.5, cex.lab = 0.5,
cex.axis = 0.5, main = "CD8+ T Samples after TMM")
# Adding a median line at each boxplot (median of the medians of each sample)
abline(h = median(apply(d_data2plot, 2, median)), col = "green", lwd = 0.6, lty = "dashed")
Side to Side Density Plot - Before (left) & After (right) TMM
par(mfrow = c(1,2))
# Distribution of our Data - Density Plot
counts_density <- apply(cd8_exp_filtered_cpm_log2, MARGIN = 2, density)
#calculate the limits across all the samples
xlim <- 0; ylim <- 0
for (i in 1:length(counts_density)) {
xlim <- range(c(xlim, counts_density[[i]]$x));
ylim <- range(c(ylim, counts_density[[i]]$y))
}
cols <- rainbow(length(counts_density))
ltys <- rep(1, length(counts_density))
#plot the first density plot to initialize the plot
plot(counts_density[[1]], xlim=xlim, ylim=ylim, type="n",
ylab="Smoothing density of log2-CPM", main="", cex.lab = 0.85)
#plot each line
for (i in 1:length(counts_density)) lines(counts_density[[i]], col=cols[i], lty=ltys[i])
#create legend
legend("topright", colnames(cd8_data2plot),
col=cols, lty=ltys, cex=0.75,
border ="blue", text.col = "green4",
merge = TRUE, bg = "gray90")
# Removing Data for sanity sake
rm(i, xlim, ylim, cols, ltys, counts_density)
# After Normalization ----
# Getting distribution graph for normalized data
counts_density <- apply(normalized_counts, MARGIN = 2, density)
#calculate the limits across all the samples
xlim <- 0; ylim <- 0
for (i in 1:length(counts_density)) {
xlim <- range(c(xlim, counts_density[[i]]$x));
ylim <- range(c(ylim, counts_density[[i]]$y))
}
cols <- rainbow(length(counts_density))
ltys <- rep(1, length(counts_density))
#plot the first density plot to initialize the plot
plot(counts_density[[1]], xlim=xlim, ylim=ylim, type="n",
ylab="Smoothing density of log2-CPM", main="", cex.lab = 0.85)
#plot each line
for (i in 1:length(counts_density)) lines(counts_density[[i]], col=cols[i], lty=ltys[i])
#create legend
legend("topright", sample.info.matrix$Label,
col=cols, lty=ltys, cex=0.75,
border ="blue", text.col = "green4",
merge = TRUE, bg = "gray90")
# Removing Data for Sanity Sake
# rm(counts_density, cols, ltys, xlim, ylim, i, cd8_data2plot)
par(mfrow = c(1,1))
Handling Biological Replicate with MDS graph
# Multidimensional Scaling Plots between Samples
plotMDS(dGEList.for.TMM, labels=sample.info.matrix$Label,
col = c("darkgreen","blue","cyan", "green")[factor(sample.info.matrix$Patient)])
Plot of Mean Variance
model_design <- model.matrix(~sample.info.matrix$Patient + sample.info.matrix$Treatment + 0)
dGEList.for.TMM <- estimateDisp(dGEList.for.TMM, model_design)
plotMeanVar(dGEList.for.TMM, show.raw.vars = TRUE, show.tagwise.vars=TRUE,
show.ave.raw.vars = TRUE,
NBline=TRUE,
show.binned.common.disp.vars = TRUE)
Identity Mapping
Used hg19 (GRCh37) human gene ensembl to map the HGNC symbol using ensembl ID as reads were aligned using hg19 reference genome.
Number of mappings that are either missing values or empty strings
ensembl_gr37 <- useMart(biomart = "ensembl", dataset = "hsapiens_gene_ensembl", host="grch37.ensembl.org")
cd8_exp_filtered$id <- gsub(pattern = "^gene:", replacement = "", x = cd8_exp_filtered$id, ignore.case = TRUE)
# head(cd8_exp_filtered)
# Now Doing the Identifier Mapping
conversion_stash <- "cd8_id_conversion.rds"
if(file.exists(conversion_stash)){
cd8_id_conversion <- readRDS(conversion_stash)
} else {
cd8_id_conversion <- getBM(attributes = c("ensembl_gene_id","hgnc_symbol"),
filters = c("ensembl_gene_id"),
values = factor(cd8_exp_filtered$id),
mart = ensembl_gr37)
saveRDS(cd8_id_conversion, conversion_stash)
}# Getting the difference between the number of mappings and the number of rows in the normalized set
# BUT this doesn't necessarily mean we are missing only that many
nrow(normalized_counts) - (sum(!is.na(cd8_id_conversion$hgnc_symbol)) - sum(nchar(cd8_id_conversion$hgnc_symbol) == 0))## [1] 2707# Merging the new identifers
# head(rownames(normalized_counts))
rownames(normalized_counts) <- gsub(pattern = "^gene:", replacement = "", x = rownames(normalized_counts),
ignore.case = TRUE)
# head(rownames(normalized_counts))
# all.y = TRUE; right outer join where the normalized_counts is preserved
# by.x = 1 refers to the ensembl_gene_id column of cd8_id_conversion, and by.y = 0 refers to the row names of the
# normalized_counts
normalized_counts_annot <- merge(x = cd8_id_conversion, y = normalized_counts,by.x = 1, by.y = 0, all.y=TRUE)
rm( current_gpl_info)There was 1 HGNC symbol duplicate that was neither an empty string nor a missing value.
The HGNC Symbol Duplicate
duplicated.hugo <- normalized_counts_annot[duplicated(normalized_counts_annot$hgnc_symbol),c(1,2)]
duplicated.hugo.matrix <- getBM(attributes = c('ensembl_gene_id', 'external_gene_name', "hgnc_symbol"),
filters = "ensembl_gene_id",
values = duplicated.hugo$ensembl_gene_id,
mart = ensembl_gr37)
# head(duplicated.hugo)the.index <- which(!(nchar(duplicated.hugo$hgnc_symbol) == 0) & !(is.na(duplicated.hugo$hgnc_symbol))) # [1] 2115
# duplicated.hugo.matrix[ the.index, ]
# ensembl_gene_id external_gene_name hgnc_symbol
# 2115 ENSG00000266036 MIR3615 MIR3615
normalized_counts_annot[which(normalized_counts_annot$hgnc_symbol == "MIR3615"), 1:6]## ensembl_gene_id hgnc_symbol pt.A.PreTreat pt.A.Cycle1 pt.A.Cycle3 pt.A.Cycle4
## 16356 ENSG00000264624 MIR3615 1.585288 1.585288 1.585288 1.585288
## 16416 ENSG00000266036 MIR3615 1.585288 1.585288 1.585288 2.205500# ensembl_gene_id hgnc_symbol pt.A.PreTreat pt.A.Cycle1 pt.A.Cycle3 pt.A.Cycle4
# 16356 ENSG00000264624 MIR3615 1.585288 1.585288 1.585288 1.585288
# 16416 ENSG00000266036 MIR3615 1.585288 1.585288 1.585288 2.205500Searching the two ensembl gene id at the http://grch37.ensembl.org/ tells me that one is forward strand and the another is reverse strand.
I’ve decided to keep both of the MIR3614 rows because the expression level was different between the forward and reverse strand, interestingly. And based on my understanding from molecular biology classes, the RNA polymerase does not know whether the genes should be transcribed in either one of the strands (i.e. in either two directions), although RNA polymerase does prematurely halt when it is on the non-coding strand.
Other 2708 genes
checked.Gene.Symbols <- checkGeneSymbols(duplicated.hugo.matrix$external_gene_name)
# sum(!is.na(checked.Gene.Symbols$Suggested.Symbol))
# RP11 prefix
Not.start.with.RP11 <- grep(x = checked.Gene.Symbols$x, ignore.case = TRUE, pattern = "^Rp11", value = TRUE, invert = TRUE)
# head(Not.start.with.RP11)Out of 2708 genes, 1475 genes start with RP11 prefix, that refer to RP11 BAC clones (n.d.). RP11 is a code identifying an individual anonymous human donor to a the BAC clone library started at Roswell Park Cancer Institute by Dr.Pieter de Jong. These genes are the genetic dark matter, and thus are kept.
# Checking those that start with RP11
length(grep(x = checked.Gene.Symbols$x, ignore.case = TRUE, pattern = "^Rp11", value = TRUE)) # [1] 1475## [1] 1475No specific pattern found in the other 1233 genes (2708 - 1475 = 1233). Kept because this portion has the potential to be significant in the downstream differential gene analysis.
# Final Dataset
conversion_stash <- "cd8_id_conversion_final.rds"
if(file.exists(conversion_stash)){
cd8_id_conversion_final <- readRDS(conversion_stash)
} else {
cd8_id_conversion_final <- getBM(attributes = c("ensembl_gene_id","hgnc_symbol", "external_gene_name"),
filters = c("ensembl_gene_id"),
values = factor(cd8_exp_filtered$id),
mart = ensembl_gr37)
saveRDS(cd8_id_conversion_final, conversion_stash)
}
normalized_counts_annot_final <- merge(x = cd8_id_conversion_final, y = normalized_counts,by.x = 1, by.y = 0, all.y=TRUE)
checked.Gene.Symbols <- checkGeneSymbols(normalized_counts_annot_final$external_gene_name)
normalized_counts_annot_final <- cbind(normalized_counts_annot_final, checked.Gene.Symbols[,c(2,3)])Two ensembl gene ids were found to be duplicates. And the rows with hgnc symbols corresponding to the suggested symbols were kept.
normalized_counts_annot_final %>% filter(!(hgnc_symbol %in% c("MIR29B1", "SNORD116-21"))) -> normalized_counts_annot_final
normalized_counts_annot_final %>% filter(ensembl_gene_id %in% c("ENSG00000226380", "ENSG00000261069"))## ensembl_gene_id hgnc_symbol external_gene_name pt.A.PreTreat pt.A.Cycle1 pt.A.Cycle3 pt.A.Cycle4 pt.B.PreTreat pt.B.Cycle1 pt.B.Cycle3 pt.B.Cycle4 pt.C.PreTreat pt.C.Cycle1 pt.C.Cycle3 pt.C.Cycle4 Approved Suggested.Symbol
## 1 ENSG00000226380 MIR29A MIR29A 4.696661 4.211401 4.740561 4.481602 7.214179 7.986271 6.406291 6.264456 5.357939 5.435683 6.215420 5.916170 TRUE MIR29A
## 2 ENSG00000261069 SNORD116-20 SNORD116-20 5.195082 5.728559 4.570866 5.436041 5.017546 5.679423 5.050664 6.210123 5.408471 5.068612 5.272534 5.479161 TRUE SNORD116-20Head() view & Dimension of my final curated data
## ensembl_gene_id hgnc_symbol external_gene_name pt.A.PreTreat pt.A.Cycle1 pt.A.Cycle3 pt.A.Cycle4 pt.B.PreTreat pt.B.Cycle1 pt.B.Cycle3 pt.B.Cycle4 pt.C.PreTreat pt.C.Cycle1 pt.C.Cycle3 pt.C.Cycle4 Approved Suggested.Symbol
## 1 ENSG00000000003 TSPAN6 TSPAN6 1.585288 1.585288 1.585288 2.205500 2.160346 2.611976 1.585288 1.585288 1.585288 1.585288 2.186122 2.149044 TRUE TSPAN6
## 2 ENSG00000000419 DPM1 DPM1 4.609000 5.228786 3.572935 4.847364 4.020287 3.625138 4.616559 4.219407 4.139144 4.192167 4.714390 3.855787 TRUE DPM1
## 3 ENSG00000000457 SCYL3 SCYL3 3.412029 3.307483 4.271783 3.990412 3.731996 4.214461 4.338088 4.516652 4.139144 4.396273 3.945020 4.231275 TRUE SCYL3
## 4 ENSG00000000460 C1orf112 C1orf112 2.598885 1.585288 2.897342 2.637845 3.150373 2.939183 3.537666 4.219407 3.145419 2.841504 2.186122 2.553360 TRUE C1orf112
## 5 ENSG00000000938 FGR FGR 5.858872 3.307483 6.213313 5.381308 4.728649 3.625138 5.810183 5.370125 5.594568 6.259603 4.325682 5.383239 TRUE FGR
## 6 ENSG00000000971 CFH CFH 3.412029 3.539195 4.378517 4.256811 2.570406 2.939183 4.231885 3.694367 3.557323 2.530738 1.585288 2.553360 TRUE CFH## [1] 17118 17The final coverage of my dataset has 17118 genes, with just one duplicate gene (same hgnc symbol). And it has 4 different treatment groups, where each group have 3 biological replicates.
There are 3 samples of each cycle (i.e. pre-treatment, cycle1, cycle 3, cycle4).
Originally there were 28383 genes & 13 instead of 12 samples that I have for the final matrix. The one cycle 2, was discarded because it had no biological replicates.
Differential Gene & gProfiler
Multidimensional Scaling Plot of the Samples
# Multidimensional Scaling Plots between Samples
plotMDS(dGEList.for.TMM, labels=sample.info.matrix$Label,
col = c("darkgreen","blue","cyan", "green")[factor(sample.info.matrix$Patient)])
Because variability not only exists between treatment cycles but also in patients, both patient and treatment have been integrated as the independent factors to do the linear fit.
Differential Gene
Limma-Trend
# Create the data matrix for linear fit
expressionMatrix <- as.matrix(normalized_counts_annot_final[,4:15])
rownames(expressionMatrix) <- normalized_counts_annot_final$ensembl_gene_id
colnames(expressionMatrix) <- colnames(normalized_counts_annot_final[,4:15])
minimalSet <- ExpressionSet(assayData=expressionMatrix)
# Making those independent variables into factors for genewise linear regression
sample.info.matrix$Treatment <- factor(sample.info.matrix$Treatment, levels = c("PreTreat", "Cycle1", "Cycle3", "Cycle4"))
sample.info.matrix$Patient <- factor(sample.info.matrix$Patient)
model_design_pat <- model.matrix(~0 + Treatment + Patient , data = sample.info.matrix)
# Contrast matrices - tells me what linear regressions contrasts.fit() subtracts to do statistical test between the genes
contrast.matrix <- makeContrasts(TreatmentCycle4-TreatmentPreTreat,
TreatmentCycle3-TreatmentPreTreat,
TreatmentCycle1-TreatmentPreTreat,
TreatmentCycle4-TreatmentCycle3,
PatientB-PatientC,
levels=model_design_pat)
# Making the linear regression models for each gene
fit <- lmFit(minimalSet, model_design_pat)
fit2 = contrasts.fit(fit, contrast.matrix)
# trend = TRUE for RNA-seq
fit2 = eBayes(fit2, trend = TRUE)
diff.gene.result.output <- function(fit, adjust.method){
summary(decideTests(fit, adjust.method = adjust.method)) %>% as.data.frame() -> try
kable(try %>% dcast(Var1 ~ Var2, value.var = "Freq") %>% arrange(-row_number())) %>%
kable_styling(bootstrap_options = "striped", full_width = F)
}Differential Gene Result Summary with Benjamini Hochberg Correction for Multiple Hypothesis Testing
| Var1 | TreatmentCycle4 - TreatmentPreTreat | TreatmentCycle3 - TreatmentPreTreat | TreatmentCycle1 - TreatmentPreTreat | TreatmentCycle4 - TreatmentCycle3 | PatientB - PatientC |
|---|---|---|---|---|---|
| Up | 0 | 0 | 0 | 0 | 72 |
| NotSig | 17118 | 17118 | 17118 | 17118 | 16969 |
| Down | 0 | 0 | 0 | 0 | 77 |
Differential Gene Result Summary with No Correction on P Value (Multiple Hypothesis Testing)
| Var1 | TreatmentCycle4 - TreatmentPreTreat | TreatmentCycle3 - TreatmentPreTreat | TreatmentCycle1 - TreatmentPreTreat | TreatmentCycle4 - TreatmentCycle3 | PatientB - PatientC |
|---|---|---|---|---|---|
| Up | 312 | 161 | 323 | 435 | 1041 |
| NotSig | 16562 | 16731 | 16161 | 16496 | 15193 |
| Down | 244 | 226 | 634 | 187 | 884 |
output.limma.trend.result <- function(fit, adj.method, expr_matrix, p_val, coeff){
limma.result <- topTable(fit,
adjust.method = adj.method,
number = nrow(expr_matrix),
coef = coeff,
p.value = p_val)
# Trying to combine the hgnc symbol & external gene name to the this differential results frame
limma.result %>% rownames_to_column %>%
rename(ensembl_gene_id = rowname) %>%
left_join(y = normalized_counts_annot_final[,1:3], by = "ensembl_gene_id" ) %>%
subset(select=c(1,8,9, 2:7)) -> limma.result
# From the annotables library
data("grch37")
grch37 <- rename(grch37, ensembl_gene_id = ensgene)
limma.result %>% left_join(y = grch37[,c(1,9)], by = "ensembl_gene_id") -> limma.result
return(limma.result)
}Cycle4.vs.Cycle3 <- output.limma.trend.result(fit = fit2, adj.method = "none", p_val = 0.05, coeff = "TreatmentCycle4 - TreatmentCycle3", expr_matrix = expressionMatrix)
Cycle3.vs.PreTreat <- output.limma.trend.result(fit = fit2, adj.method = "none", p_val = 0.05, coeff = "TreatmentCycle3 - TreatmentPreTreat", expr_matrix = expressionMatrix)
PatientB.vs.PatientC <- output.limma.trend.result(fit = fit2, adj.method = "none", p_val = 0.05, coeff = "PatientB - PatientC", expr_matrix = expressionMatrix)Quasi-likelihood Test - EdgeR
Unfortunately, no statistically significant genes showed up with the quasi-likelihood test, even without the multiple hypothesis testing corrections. This made me select the genes from the Limma-Trend analysis.
d = DGEList(counts=minimalSet, group= sample.info.matrix$Treatment)
d <- estimateDisp(d, model_design_pat)
d <- calcNormFactors(d)
fit <- glmQLFit(d, model_design_pat)
contrast.matrix <- makeContrasts(TreatmentCycle4-TreatmentCycle3,
levels=model_design_pat)
qlf.cycle4_vs_cycle3 <- glmQLFTest(fit, contrast= contrast.matrix)
contrast.matrix <- makeContrasts(PatientB-PatientC,
levels=model_design_pat)
qlf.B_vs_C <- glmQLFTest(fit, contrast= contrast.matrix)
contrast.matrix <- makeContrasts(TreatmentCycle3-TreatmentPreTreat,
levels=model_design_pat)
qlf <- glmQLFTest(fit, contrast= contrast.matrix)With correction
summary(decideTests(qlf.cycle4_vs_cycle3, adjust.method = "BH")) %>% as.data.frame() %>% arrange(-row_number()) %>%
dplyr::select(c(-2)) %>% rename("Cycle 4 vs Cycle 3"= Var1)## Cycle 4 vs Cycle 3 Freq
## 1 Up 0
## 2 NotSig 17118
## 3 Down 0Without correction
summary(decideTests(qlf.cycle4_vs_cycle3, adjust.method = "none"))%>% as.data.frame() %>% arrange(-row_number()) %>%
dplyr::select(c(-2)) %>% rename("Cycle 4 vs Cycle 3"= Var1)## Cycle 4 vs Cycle 3 Freq
## 1 Up 0
## 2 NotSig 17118
## 3 Down 0With correction
summary(decideTests(qlf.B_vs_C, adjust.method = "BH")) %>% as.data.frame() %>% arrange(-row_number()) %>%
dplyr::select(c(-2)) %>% rename("Patient B vs Patient C"= Var1)## Patient B vs Patient C Freq
## 1 Up 0
## 2 NotSig 17118
## 3 Down 0Without correction
summary(decideTests(qlf.B_vs_C, adjust.method = "none")) %>% as.data.frame() %>% arrange(-row_number()) %>%
dplyr::select(c(-2)) %>% rename("Patient B vs Patient C"= Var1)## Patient B vs Patient C Freq
## 1 Up 4
## 2 NotSig 17112
## 3 Down 2With Correction
summary(decideTests(qlf, adjust.method = "BH")) %>% as.data.frame() %>% arrange(-row_number()) %>%
dplyr::select(c(-2)) %>% rename("Cycle 3 vs Pre Treatment"= Var1)## Cycle 3 vs Pre Treatment Freq
## 1 Up 0
## 2 NotSig 17118
## 3 Down 0Without Correction
summary(decideTests(qlf, adjust.method = "none")) %>% as.data.frame() %>% arrange(-row_number()) %>%
dplyr::select(c(-2)) %>% rename("Cycle 3 vs Pre Treatment"= Var1)## Cycle 3 vs Pre Treatment Freq
## 1 Up 0
## 2 NotSig 17118
## 3 Down 0Volcano Plots
This is for reference to the number of differential genes detected without multiple hypothesis testing correction in limma-trend analysis. These genes were used to generate the volcano plots
summary(decideTests(fit2, adjust.method = "none", p.value = 0.05)) %>% as.data.frame() -> try
kable(try %>% dcast(Var1 ~ Var2) %>% arrange(-row_number())) %>%
kable_styling(bootstrap_options = "striped", full_width = F)| Var1 | TreatmentCycle4 - TreatmentPreTreat | TreatmentCycle3 - TreatmentPreTreat | TreatmentCycle1 - TreatmentPreTreat | TreatmentCycle4 - TreatmentCycle3 | PatientB - PatientC |
|---|---|---|---|---|---|
| Up | 312 | 161 | 323 | 435 | 1041 |
| NotSig | 16562 | 16731 | 16161 | 16496 | 15193 |
| Down | 244 | 226 | 634 | 187 | 884 |
# Volcano Plot
gene.names <- data.frame(ensembl_gene_id = rownames(fit2$coefficients))
gene.names %>% left_join(normalized_counts_annot_final, by = "ensembl_gene_id") %>%
dplyr::select(c(1,17)) -> gene.names ## Warning: Column `ensembl_gene_id` joining factor and character vector, coercing into character vector# colnames(fit2$coefficients)
# [1] "TreatmentCycle4 - TreatmentPreTreat"
# [2] "TreatmentCycle3 - TreatmentPreTreat"
# [3] "TreatmentCycle1 - TreatmentPreTreat"
# [4] "TreatmentCycle4 - TreatmentCycle3"
# [5] "PatientB - PatientC"
generate_volcano.plot.data <- function(fit, index){
output.frame <- data.frame(log2FC = fit$coefficients[,index], p_value = fit$p.value[,index],
Color = "grey", stringsAsFactors = "FALSE")
output.frame <- cbind(gene.names, output.frame)
output.frame$Color[output.frame$p_value < 0.05] = "blue"
output.frame %>%
mutate(neg_log10_p_value = -log10(output.frame$p_value)) -> output.frame
return(output.frame)
}
# Cycle 4 vs Cycle 3
volcano.plot.Cycle4.Cycle3 <- generate_volcano.plot.data(fit2, index = 4)
# IFN gamma index
IFNG.index <- grep(pattern = "^IFNG$", x = volcano.plot.Cycle4.Cycle3$Suggested.Symbol,
ignore.case = TRUE)
# Cycle 3 vs Pre-Treatment
volcano.plot.Cycle3.PreTreat <- generate_volcano.plot.data(fit2, index = 2)
# Patient B vs Patient C
volcano.plot.PatientB.PatientC <- generate_volcano.plot.data(fit2, index = 5)
output.volcano.plot <- function(obj, x, y){
plot(x = obj$log2FC, y = obj$neg_log10_p_value,
pch = 16, cex = 0.5, xlab = "Log2 Fold Change", ylab = "-log10(P-value)",
col = obj$Color)
points(obj$log2FC[IFNG.index],
obj$neg_log10_p_value[IFNG.index], col = "red", cex = 1.5)
legend(x = x, y = y, c("Not significant", "Significant", "IFN-g"),
cex = 1.0, col = c("grey", "blue","red"), pch = c(16, 16, 1),
bty = "n")
}Interferon gamma gene will be highlighted in all volcano plots, as in wet lab it is used as an indicator to check whether CD8 T cells are activated or not, using flow cytometry.
Treatment Cycle 4 vs Cycle 3 Volcano Plot using Limma Results
Treatment Cycle 3 vs Pre-Treatment Volcano Plot using Limma Results
Patient B vs Patient C Volcano Plot using Limma Results
For the first time, interferon gamma is amongst the statistically significant genes. This plot shows it is relatively downregulated in patient B compared to patient C, or relatively upregulated in patient C compared to patient B,
Heatmaps
Visualizing the top hits as heatmaps and Checking whether conditions cluster together or not
# Create a numerical matrix that we can create a heatmap from
heatmap_matrix <- normalized_counts_annot_final[,4:15]
rownames(heatmap_matrix) <- normalized_counts_annot_final$ensembl_gene_id
colnames(heatmap_matrix) <- colnames(normalized_counts_annot_final)[4:15]
output.heatmap <- function(compare.1, compare.2, gene.frame){
heatmap_matrix_tophits <- t(
scale(t(heatmap_matrix[
which(rownames(heatmap_matrix) %in% gene.frame$ensembl_gene_id),])))
if(min(heatmap_matrix_tophits) == 0){
heatmap_col = colorRamp2(c( 0, max(heatmap_matrix_tophits)),
c( "white", "red"))
} else {
heatmap_col = colorRamp2(c(min(heatmap_matrix_tophits), 0, max(heatmap_matrix_tophits)), c("blue", "white", "red"))
}
# Aligning Cycle-wise
index.1 <- grep(colnames(heatmap_matrix_tophits),
pattern = compare.1)
index.2 <- grep(colnames(heatmap_matrix_tophits),
pattern = compare.2)
index.3 <- 1:12
index.3 <- setdiff(index.3, index.1)
index.3 <- setdiff(index.3, index.2)
# index.3
heatmap_matrix_tophits<- heatmap_matrix_tophits[, c(index.1, index.2, index.3 )]
# Building Heatmap
current_heatmap <- Heatmap(as.matrix(heatmap_matrix_tophits),
cluster_rows = TRUE,
cluster_columns = TRUE,
show_row_dend = TRUE,
show_column_dend = TRUE,
col=heatmap_col,
show_column_names = TRUE,
show_row_names = FALSE,
show_heatmap_legend = TRUE,
heatmap_legend_param = list(title = "Normalized Expr Lvl"),
)
current_heatmap
}Cycle 4 vs Cycle 3 Top Hits
# Heatmap for Cycle 4 vs Cycle 3 Top hits
output.heatmap(compare.1 = "Cycle4", compare.2 = "Cycle3", gene.frame = Cycle4.vs.Cycle3)
Cycle 3 vs Pre-Treatment Top Hits
# Heatmap for Cycle 3 vs Pre-Treatment
output.heatmap(compare.1 = "Cycle3", compare.2 = "PreTreat", gene.frame = Cycle3.vs.PreTreat)
Patient B vs Patient C Top Hits
# Heatmap for Patient B vs Patient C
output.heatmap(compare.1 = "pt.B", compare.2 = "pt.C", gene.frame = PatientB.vs.PatientC)
My conditions of patient B and patient C do cluster together, which suggest that patients respond differently to anti-PD-1 therapy. Interestingly, patient A and C seems to have similar upregulated and downregulated genes compared to patient B.
Thresholded Overrepresentation Analysis using gProfiler
summary(decideTests(fit2, adjust.method = "none", p.value = 0.05)) %>% as.data.frame() -> try
kable(try %>% dcast(Var1 ~ Var2) %>% arrange(-row_number())) %>%
kable_styling(bootstrap_options = "striped", full_width = F)| Var1 | TreatmentCycle4 - TreatmentPreTreat | TreatmentCycle3 - TreatmentPreTreat | TreatmentCycle1 - TreatmentPreTreat | TreatmentCycle4 - TreatmentCycle3 | PatientB - PatientC |
|---|---|---|---|---|---|
| Up | 312 | 161 | 323 | 435 | 1041 |
| NotSig | 16562 | 16731 | 16161 | 16496 | 15193 |
| Down | 244 | 226 | 634 | 187 | 884 |
Used Annotation Version
https://biit.cs.ut.ee/gprofiler/page/faq
So according to the FAQ section of gprofiler under the question “How often is g:Profiler updated?”, it follows ENSEMBL quarterly update cycle with few weeks to months delay. And the current data source version (annotation version) can be seen from “Show data versions” link under the “Data sources” option.
As of February 29th which was when I ran my gProfiler analysis on, it uses:
GO:MF – releases/2019-07-01
GO:CC – releases/2019-07-01
GO:BP – releases/2019-07-01
KEGG – KEGG FTP Release 2019-09-30
REAC – annotations: ensembl/ classes: 2019-10-2
WP – 20190910
TF – annotations: TRANSFAC Release 2019.1/ classes: v2
MIRNA – Release 7.0
HPA – annotations: HPA website: 2017-12-01/ classes: script: 2018-03-19
CORUM – 03.09.2018 Corum 3.0
HP – hpo.annotations.monthly #157
Turn this code off if you want to get fresh results from g:GOSt.
# this code is just to not let gost run all the time everytime I rerun the code.
# turn off this code if you want to get new results from gost
# Loading in the gost data
tryCatch(
{load("ORA_gosts.RData")},
error = function(e){}
)Treatment Cycle 4 vs Cycle 3
# First divide the list into upregulated and downregulated genes
Cycle4.vs.Cycle3 %>% distinct(external_gene_name, .keep_all = TRUE) -> Cycle4.vs.Cycle3
Cycle4.vs.Cycle3 %>% filter(logFC > 0 & P.Value < 0.05) -> Up_Regulated_Cycle4.vs.Cycle3
Cycle4.vs.Cycle3 %>% filter(logFC < 0 & P.Value < 0.05) -> Down_Regulated_Cycle4.vs.Cycle3
# Do not rerun this if already ran
if(!all(c("upreg_genelist_cycle4_cycle3", "upreg_genelist_cycle4_cycle3_hgnc") %in% ls())){
upreg_genelist_cycle4_cycle3 <- gost(query = Up_Regulated_Cycle4.vs.Cycle3$external_gene_name,
organism = "hsapiens", evcodes = TRUE, user_threshold = 0.05, correction_method = "fdr")
upreg_genelist_cycle4_cycle3_hgnc <- gost(query = Up_Regulated_Cycle4.vs.Cycle3$hgnc_symbol,
organism = "hsapiens", evcodes = TRUE, user_threshold = 0.05, correction_method = "fdr")
}
if(!exists(x = "upreg_genelist_cycle4_cycle3_ensembl")){
upreg_genelist_cycle4_cycle3_ensembl <- gost(query = Up_Regulated_Cycle4.vs.Cycle3$ensembl_gene_id,
organism = "hsapiens", evcodes = TRUE, user_threshold = 0.05, correction_method = "fdr")
}
# Do not rerun if already exists
if(!all(c("downreg_genelist_cycle4_cycle3_ensembl","Cycle4_Cycle3_Whole_gene") %in% ls())){
downreg_genelist_cycle4_cycle3_ensembl <- gost(query = Down_Regulated_Cycle4.vs.Cycle3$ensembl_gene_id,
organism = "hsapiens", evcodes = TRUE, user_threshold = 0.05,
correction_method = "fdr")
Cycle4_Cycle3_Whole_gene <- gost(query = Cycle4.vs.Cycle3$ensembl_gene_id,
organism = "hsapiens", evcodes = TRUE, user_threshold = 0.05,
correction_method = "fdr")
}Upregulated genes with BH FDR correction < 0.05
result.up.cycle4.cycle3 <- upreg_genelist_cycle4_cycle3_ensembl$result
result.up.cycle4.cycle3 <- result.up.cycle4.cycle3 %>% dplyr::select(c(3:16)) %>% subset(select=c(7,9, 1:6,8, 14))
# nrow(result.up.cycle4.cycle3)
kable(result.up.cycle4.cycle3) %>%
kable_styling() %>%
scroll_box(width = "800px", height = "500px")| term_id | term_name | p_value | term_size | query_size | intersection_size | precision | recall | source | intersection |
|---|---|---|---|---|---|---|---|---|---|
| CORUM:120 | Lymphotoxin beta receptor complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000227507 |
| CORUM:5649 | FARP2-NRP1-PlexinA4 complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000221866 |
| CORUM:5760 | PLXNA4-RANBPM complex | 0.0413475 | 2 | 29 | 1 | 0.0344828 | 0.5000000 | CORUM | ENSG00000221866 |
| CORUM:6056 | APP-TNFRSF21 complex | 0.0413475 | 2 | 29 | 1 | 0.0344828 | 0.5000000 | CORUM | ENSG00000142192 |
| CORUM:6203 | TFAP2C-Myc-KDM5B complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000136997 |
| CORUM:6235 | c-Fos-c-Jun-SAF-1 complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000170345 |
| CORUM:6354 | Sox4-beta-catenin-p300 complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000124766 |
| CORUM:6437 | GABBR1-GABBR2 complex | 0.0413475 | 2 | 29 | 1 | 0.0344828 | 0.5000000 | CORUM | ENSG00000204681 |
| CORUM:6487 | CUL4B-DDB1-TLE2 complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000065717 |
| CORUM:6616 | CADM1-4.1B-MPP3 complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000182985 |
| CORUM:6900 | Ubiquitin E3 ligase (CUL1, FBXO10, SKP1) | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000147912 |
| CORUM:6935 | MYC-TRRAP-KAT2A complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000136997 |
| CORUM:6956 | REP-RGGT-Rab complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000188419 |
| CORUM:7281 | BIN1-EHBP1-RAB8A complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000115504 |
| CORUM:7529 | APP-Abeta42-VDAC1 complex | 0.0413475 | 2 | 29 | 1 | 0.0344828 | 0.5000000 | CORUM | ENSG00000142192 |
| CORUM:7574 | APP-PSEN1 complex | 0.0413475 | 2 | 29 | 1 | 0.0344828 | 0.5000000 | CORUM | ENSG00000142192 |
| CORUM:7575 | APP-PSEN2 complex | 0.0413475 | 2 | 29 | 1 | 0.0344828 | 0.5000000 | CORUM | ENSG00000142192 |
| CORUM:7577 | APP-APBB1-KAT5 complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000142192 |
| CORUM:7579 | APP(AICD)-MED12 complex | 0.0413475 | 2 | 29 | 1 | 0.0344828 | 0.5000000 | CORUM | ENSG00000142192 |
| CORUM:7587 | APP(AICD)-FOXO3 complex | 0.0413475 | 2 | 29 | 1 | 0.0344828 | 0.5000000 | CORUM | ENSG00000142192 |
| CORUM:3124 | TLE1-TLE2 complex | 0.0413475 | 2 | 29 | 1 | 0.0344828 | 0.5000000 | CORUM | ENSG00000065717 |
| CORUM:7588 | APP(AICD)-FOXO1 complex | 0.0413475 | 2 | 29 | 1 | 0.0344828 | 0.5000000 | CORUM | ENSG00000142192 |
| CORUM:3123 | TLE2 homodimer complex | 0.0413475 | 1 | 29 | 1 | 0.0344828 | 1.0000000 | CORUM | ENSG00000065717 |
| CORUM:3092 | APP-TOM40 complex | 0.0413475 | 2 | 29 | 1 | 0.0344828 | 0.5000000 | CORUM | ENSG00000142192 |
| CORUM:143 | APP-APBB1-LRP1 complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000142192 |
| CORUM:428 | Molybdopterin synthase | 0.0413475 | 1 | 29 | 1 | 0.0344828 | 1.0000000 | CORUM | ENSG00000164172 |
| CORUM:1146 | Cleavage stimulation factor | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000176102 |
| CORUM:1707 | IL2-IL2RA-IL2RB complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000134460 |
| CORUM:2266 | PPP3CA-PPP3CA-RCAN1 complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000159200 |
| CORUM:2431 | ITGA2-ITGB1-COL6A3 complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000163359 |
| CORUM:2434 | ITGA1-ITGB1-COL6A3 complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000163359 |
| CORUM:2537 | PKC-alpha-PLD1-PLC-gamma-2 signaling complex, lacritin stimulated | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000154229 |
| CORUM:2649 | MYC-DNMT3A-ZBTB17 complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000136997 |
| CORUM:3093 | APP-TIM23 complex | 0.0413475 | 2 | 29 | 1 | 0.0344828 | 0.5000000 | CORUM | ENSG00000142192 |
| CORUM:7589 | APP(AICD)-FOXO4 complex | 0.0413475 | 2 | 29 | 1 | 0.0344828 | 0.5000000 | CORUM | ENSG00000142192 |
| CORUM:2693 | NFAT-JUN-FOS DNA-protein complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000170345 |
| CORUM:2694 | ERG-JUN-FOS DNA-protein complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000170345 |
| CORUM:2695 | ETS2-FOS-JUN complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000170345 |
| CORUM:2711 | Amyloid beta protein homo-oligomer complex | 0.0413475 | 1 | 29 | 1 | 0.0344828 | 1.0000000 | CORUM | ENSG00000142192 |
| CORUM:2882 | ITGA5-ITGB3-COL6A3 complex | 0.0413475 | 3 | 29 | 1 | 0.0344828 | 0.3333333 | CORUM | ENSG00000163359 |
| CORUM:3052 | MYC-MAX complex | 0.0413475 | 2 | 29 | 1 | 0.0344828 | 0.5000000 | CORUM | ENSG00000136997 |
| CORUM:2655 | MYC-MAX complex | 0.0413475 | 2 | 29 | 1 | 0.0344828 | 0.5000000 | CORUM | ENSG00000136997 |
| CORUM:2692 | SMAD3-SMAD4-cJun-cFos complex | 0.0490754 | 4 | 29 | 1 | 0.0344828 | 0.2500000 | CORUM | ENSG00000170345 |
| CORUM:7534 | CTNNB1-EPCAM-FHL2-LEF1 complex | 0.0490754 | 4 | 29 | 1 | 0.0344828 | 0.2500000 | CORUM | ENSG00000138795 |
| CORUM:2754 | JUND-FOSB-SMAD3-SMAD4 complex | 0.0490754 | 4 | 29 | 1 | 0.0344828 | 0.2500000 | CORUM | ENSG00000125740 |
| CORUM:2909 | PLC-gamma-2-Syk-LAT-FcR-gamma complex | 0.0490754 | 4 | 29 | 1 | 0.0344828 | 0.2500000 | CORUM | ENSG00000165025 |
| CORUM:2653 | MYC-MAX-KAT2A-TRRAP complex | 0.0490754 | 4 | 29 | 1 | 0.0344828 | 0.2500000 | CORUM | ENSG00000136997 |
48 upregulated genesets are returned, with 47 of them from CORUM and the last one from WP.
The unfortunately part of the CORUM terms is that these terms refer to protein complexes, and all of them have just one intersection gene, which means these terms are not meaningful.
There is one WP term at the bottom referring to IL-2 signaling pathway. IL-2 is a required cytokine that serves as stimulatory signal for naive CD8 T cells to become activated. So after treatment cycle 4, compared to cycle 3, CD8 T cells are activated to an extent
Downregulated genes with BH FDR correction < 0.05
result.down.cycle4.cycle3 <- downreg_genelist_cycle4_cycle3_ensembl$result
result.down.cycle4.cycle3 <- result.down.cycle4.cycle3 %>% dplyr::select(c(3:16)) %>% subset(select=c(7,9, 1:6,8, 14))
# nrow(result.down.cycle4.cycle3)
kable(result.down.cycle4.cycle3) %>%
kable_styling() %>%
scroll_box(width = "800px", height = "500px")| term_id | term_name | p_value | term_size | query_size | intersection_size | precision | recall | source | intersection |
|---|---|---|---|---|---|---|---|---|---|
| CORUM:2774 | MDC1-H2AFX-TP53BP1 complex | 0.0321464 | 3 | 30 | 2 | 0.0666667 | 0.6666667 | CORUM | ENSG00000137337,ENSG00000188486 |
| GO:0001726 | ruffle | 0.0077442 | 177 | 124 | 8 | 0.0645161 | 0.0451977 | GO:CC | ENSG00000138448,ENSG00000163719,ENSG00000120318,ENSG00000132613,ENSG00000136044,ENSG00000088992,ENSG00000197122,ENSG00000196586 |
| GO:0032587 | ruffle membrane | 0.0077442 | 94 | 124 | 6 | 0.0483871 | 0.0638298 | GO:CC | ENSG00000138448,ENSG00000132613,ENSG00000136044,ENSG00000088992,ENSG00000197122,ENSG00000196586 |
| GO:0005622 | intracellular | 0.0083474 | 14626 | 124 | 113 | 0.9112903 | 0.0077260 | GO:CC | ENSG00000181588,ENSG00000136114,ENSG00000167967,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000137843,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000178878,ENSG00000183963,ENSG00000100109,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000112282,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000147443,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000156463,ENSG00000170266,ENSG00000154124,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000185864,ENSG00000065970,ENSG00000011021,ENSG00000164169,ENSG00000138311,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000175544,ENSG00000136937,ENSG00000136044,ENSG00000198000,ENSG00000188277,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000105393,ENSG00000103966,ENSG00000116857,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000149591,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000110090,ENSG00000109956,ENSG00000186654,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| GO:0031256 | leading edge membrane | 0.0109020 | 174 | 124 | 7 | 0.0564516 | 0.0402299 | GO:CC | ENSG00000138448,ENSG00000132613,ENSG00000136044,ENSG00000088992,ENSG00000197122,ENSG00000196586,ENSG00000115266 |
| GO:0031941 | filamentous actin | 0.0109020 | 38 | 124 | 4 | 0.0322581 | 0.1052632 | GO:CC | ENSG00000120913,ENSG00000183963,ENSG00000196586,ENSG00000115266 |
| GO:0005884 | actin filament | 0.0109020 | 121 | 124 | 6 | 0.0483871 | 0.0495868 | GO:CC | ENSG00000120913,ENSG00000183963,ENSG00000167460,ENSG00000197122,ENSG00000196586,ENSG00000115266 |
| GO:0005773 | vacuole | 0.0143446 | 797 | 124 | 15 | 0.1209677 | 0.0188206 | GO:CC | ENSG00000157954,ENSG00000188229,ENSG00000168890,ENSG00000186187,ENSG00000100284,ENSG00000086289,ENSG00000170266,ENSG00000011021,ENSG00000197122,ENSG00000116857,ENSG00000215305,ENSG00000198925,ENSG00000078804,ENSG00000196586,ENSG00000155252 |
| GO:0043229 | intracellular organelle | 0.0146729 | 12840 | 124 | 102 | 0.8225806 | 0.0079439 | GO:CC | ENSG00000181588,ENSG00000167967,ENSG00000080823,ENSG00000137843,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000178878,ENSG00000183963,ENSG00000100109,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000112282,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000156463,ENSG00000170266,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000185864,ENSG00000065970,ENSG00000011021,ENSG00000138311,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000136937,ENSG00000136044,ENSG00000198000,ENSG00000188277,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000105393,ENSG00000103966,ENSG00000116857,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000110090,ENSG00000109956,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000145029,ENSG00000112511 |
| GO:0031252 | cell leading edge | 0.0206354 | 417 | 124 | 10 | 0.0806452 | 0.0239808 | GO:CC | ENSG00000138448,ENSG00000163719,ENSG00000119328,ENSG00000120318,ENSG00000132613,ENSG00000136044,ENSG00000088992,ENSG00000197122,ENSG00000196586,ENSG00000115266 |
| GO:0005654 | nucleoplasm | 0.0329980 | 4012 | 124 | 42 | 0.3387097 | 0.0104686 | GO:CC | ENSG00000167967,ENSG00000137843,ENSG00000157954,ENSG00000106009,ENSG00000169217,ENSG00000106991,ENSG00000197903,ENSG00000172273,ENSG00000178878,ENSG00000100109,ENSG00000133131,ENSG00000077721,ENSG00000172059,ENSG00000112282,ENSG00000111641,ENSG00000006459,ENSG00000119328,ENSG00000145020,ENSG00000116809,ENSG00000156463,ENSG00000134901,ENSG00000185864,ENSG00000065970,ENSG00000187051,ENSG00000136937,ENSG00000076321,ENSG00000088992,ENSG00000105393,ENSG00000142252,ENSG00000073584,ENSG00000198742,ENSG00000148737,ENSG00000153786,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000196586,ENSG00000145029,ENSG00000112511 |
| GO:0043231 | intracellular membrane-bounded organelle | 0.0344214 | 11067 | 124 | 90 | 0.7258065 | 0.0081323 | GO:CC | ENSG00000181588,ENSG00000167967,ENSG00000080823,ENSG00000137843,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000188229,ENSG00000186281,ENSG00000197903,ENSG00000111666,ENSG00000172273,ENSG00000178878,ENSG00000100109,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000145569,ENSG00000085377,ENSG00000112282,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000116809,ENSG00000086289,ENSG00000156463,ENSG00000170266,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000185864,ENSG00000065970,ENSG00000011021,ENSG00000138311,ENSG00000152253,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000136937,ENSG00000136044,ENSG00000198000,ENSG00000188277,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000105393,ENSG00000103966,ENSG00000116857,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000139351,ENSG00000198742,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000110090,ENSG00000109956,ENSG00000155252,ENSG00000115266,ENSG00000145029,ENSG00000112511 |
| GO:0043226 | organelle | 0.0392633 | 13720 | 124 | 105 | 0.8467742 | 0.0076531 | GO:CC | ENSG00000181588,ENSG00000167967,ENSG00000146955,ENSG00000080823,ENSG00000137843,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000178878,ENSG00000183963,ENSG00000100109,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000112282,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000156463,ENSG00000170266,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000185864,ENSG00000065970,ENSG00000011021,ENSG00000138311,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000188277,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000105393,ENSG00000103966,ENSG00000116857,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000110090,ENSG00000109956,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000145029,ENSG00000112511 |
| GO:0005737 | cytoplasm | 0.0392633 | 11634 | 124 | 93 | 0.7500000 | 0.0079938 | GO:CC | ENSG00000181588,ENSG00000136114,ENSG00000167967,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000137843,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000178878,ENSG00000183963,ENSG00000100109,ENSG00000141682,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000196547,ENSG00000186187,ENSG00000100284,ENSG00000184047,ENSG00000145020,ENSG00000147443,ENSG00000120318,ENSG00000086289,ENSG00000170266,ENSG00000154124,ENSG00000139977,ENSG00000134901,ENSG00000011021,ENSG00000164169,ENSG00000138311,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000175544,ENSG00000136937,ENSG00000136044,ENSG00000188277,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000105393,ENSG00000103966,ENSG00000116857,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000131188,ENSG00000177380,ENSG00000149591,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000156256,ENSG00000170291,ENSG00000147526,ENSG00000186834,ENSG00000078804,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000110090,ENSG00000109956,ENSG00000186654,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000259431,ENSG00000112511 |
| GO:0030027 | lamellipodium | 0.0468358 | 198 | 124 | 6 | 0.0483871 | 0.0303030 | GO:CC | ENSG00000138448,ENSG00000119328,ENSG00000120318,ENSG00000132613,ENSG00000088992,ENSG00000115266 |
| GO:0000323 | lytic vacuole | 0.0468358 | 697 | 124 | 12 | 0.0967742 | 0.0172166 | GO:CC | ENSG00000188229,ENSG00000168890,ENSG00000186187,ENSG00000100284,ENSG00000086289,ENSG00000170266,ENSG00000011021,ENSG00000197122,ENSG00000116857,ENSG00000215305,ENSG00000196586,ENSG00000155252 |
| GO:0016604 | nuclear body | 0.0468358 | 794 | 124 | 13 | 0.1048387 | 0.0163728 | GO:CC | ENSG00000169217,ENSG00000106991,ENSG00000172273,ENSG00000100109,ENSG00000172059,ENSG00000119328,ENSG00000076321,ENSG00000105393,ENSG00000142252,ENSG00000148737,ENSG00000137337,ENSG00000188486,ENSG00000078804 |
| GO:0031253 | cell projection membrane | 0.0468358 | 335 | 124 | 8 | 0.0645161 | 0.0238806 | GO:CC | ENSG00000138448,ENSG00000132613,ENSG00000136044,ENSG00000163803,ENSG00000088992,ENSG00000197122,ENSG00000196586,ENSG00000115266 |
| GO:0043227 | membrane-bounded organelle | 0.0468358 | 12584 | 124 | 98 | 0.7903226 | 0.0077877 | GO:CC | ENSG00000181588,ENSG00000167967,ENSG00000146955,ENSG00000080823,ENSG00000137843,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000178878,ENSG00000100109,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000145569,ENSG00000085377,ENSG00000112282,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000116809,ENSG00000086289,ENSG00000156463,ENSG00000170266,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000185864,ENSG00000065970,ENSG00000011021,ENSG00000138311,ENSG00000152253,ENSG00000167460,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000136937,ENSG00000136044,ENSG00000198000,ENSG00000188277,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000105393,ENSG00000103966,ENSG00000116857,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000110090,ENSG00000109956,ENSG00000155252,ENSG00000115266,ENSG00000145029,ENSG00000112511 |
| GO:0120025 | plasma membrane bounded cell projection | 0.0468358 | 2200 | 124 | 26 | 0.2096774 | 0.0118182 | GO:CC | ENSG00000080823,ENSG00000196569,ENSG00000138448,ENSG00000163719,ENSG00000166813,ENSG00000119328,ENSG00000120318,ENSG00000132613,ENSG00000141577,ENSG00000175544,ENSG00000168026,ENSG00000136044,ENSG00000128594,ENSG00000163803,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000215305,ENSG00000131188,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000128309,ENSG00000196586,ENSG00000155252,ENSG00000115266 |
| GO:0005764 | lysosome | 0.0468358 | 697 | 124 | 12 | 0.0967742 | 0.0172166 | GO:CC | ENSG00000188229,ENSG00000168890,ENSG00000186187,ENSG00000100284,ENSG00000086289,ENSG00000170266,ENSG00000011021,ENSG00000197122,ENSG00000116857,ENSG00000215305,ENSG00000196586,ENSG00000155252 |
| TF:M03978_0 | Factor: ETS1; motif: GCCGGAWGTACTTCCGGN; match class: 0 | 0.0004189 | 12175 | 135 | 111 | 0.8222222 | 0.0091170 | TF | ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000259316,ENSG00000179698,ENSG00000167967,ENSG00000146955,ENSG00000172014,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000196569,ENSG00000137843,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000254413,ENSG00000188229,ENSG00000127824,ENSG00000197903,ENSG00000138448,ENSG00000172273,ENSG00000178878,ENSG00000183963,ENSG00000188394,ENSG00000100109,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000163719,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000112282,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000147443,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000156463,ENSG00000170266,ENSG00000154124,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000065970,ENSG00000011021,ENSG00000164169,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000175544,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000128594,ENSG00000088992,ENSG00000105393,ENSG00000103966,ENSG00000116857,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000139351,ENSG00000129968,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000170445,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431 |
| TF:M03978 | Factor: ETS1; motif: GCCGGAWGTACTTCCGGN | 0.0004189 | 12175 | 135 | 111 | 0.8222222 | 0.0091170 | TF | ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000259316,ENSG00000179698,ENSG00000167967,ENSG00000146955,ENSG00000172014,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000196569,ENSG00000137843,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000254413,ENSG00000188229,ENSG00000127824,ENSG00000197903,ENSG00000138448,ENSG00000172273,ENSG00000178878,ENSG00000183963,ENSG00000188394,ENSG00000100109,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000163719,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000112282,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000147443,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000156463,ENSG00000170266,ENSG00000154124,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000065970,ENSG00000011021,ENSG00000164169,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000175544,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000128594,ENSG00000088992,ENSG00000105393,ENSG00000103966,ENSG00000116857,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000139351,ENSG00000129968,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000170445,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431 |
| TF:M00803_1 | Factor: E2F; motif: GGCGSG; match class: 1 | 0.0032098 | 10249 | 135 | 97 | 0.7185185 | 0.0094643 | TF | ENSG00000181588,ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000179698,ENSG00000167967,ENSG00000172014,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000188092,ENSG00000088876,ENSG00000188229,ENSG00000127824,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000183963,ENSG00000100109,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000184047,ENSG00000119328,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000170266,ENSG00000154124,ENSG00000134901,ENSG00000070476,ENSG00000065970,ENSG00000011021,ENSG00000138311,ENSG00000167460,ENSG00000132613,ENSG00000141577,ENSG00000187051,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000088992,ENSG00000103966,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000167378,ENSG00000151746,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| TF:M09636_1 | Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG; match class: 1 | 0.0118437 | 14176 | 135 | 118 | 0.8740741 | 0.0083239 | TF | ENSG00000181588,ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000179698,ENSG00000167967,ENSG00000172014,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000254413,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000183963,ENSG00000188394,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000112282,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000147443,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000170266,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000065970,ENSG00000011021,ENSG00000138311,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000188277,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000105393,ENSG00000103966,ENSG00000116857,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000149591,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| TF:M00716_1 | Factor: ZF5; motif: GSGCGCGR; match class: 1 | 0.0118437 | 14196 | 135 | 118 | 0.8740741 | 0.0083122 | TF | ENSG00000181588,ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000179698,ENSG00000167967,ENSG00000172014,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000183963,ENSG00000100109,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000170266,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000065970,ENSG00000011021,ENSG00000164169,ENSG00000138311,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000141577,ENSG00000187051,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000188277,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000103966,ENSG00000116857,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000149591,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000110090,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| TF:M08209_0 | Factor: E2F-3:FOXO6; motif: NAATGACACGCGCCCMC; match class: 0 | 0.0185259 | 13782 | 135 | 115 | 0.8518519 | 0.0083442 | TF | ENSG00000181588,ENSG00000136114,ENSG00000221916,ENSG00000259316,ENSG00000179698,ENSG00000167967,ENSG00000172014,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000196569,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000254413,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000178878,ENSG00000183963,ENSG00000141682,ENSG00000133131,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000141854,ENSG00000176531,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000147443,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000156463,ENSG00000170266,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000185864,ENSG00000065970,ENSG00000011021,ENSG00000138311,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000175544,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000163803,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000103966,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000073584,ENSG00000131188,ENSG00000139351,ENSG00000149591,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000170445,ENSG00000110090,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| TF:M08209 | Factor: E2F-3:FOXO6; motif: NAATGACACGCGCCCMC | 0.0185259 | 13782 | 135 | 115 | 0.8518519 | 0.0083442 | TF | ENSG00000181588,ENSG00000136114,ENSG00000221916,ENSG00000259316,ENSG00000179698,ENSG00000167967,ENSG00000172014,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000196569,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000254413,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000178878,ENSG00000183963,ENSG00000141682,ENSG00000133131,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000141854,ENSG00000176531,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000147443,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000156463,ENSG00000170266,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000185864,ENSG00000065970,ENSG00000011021,ENSG00000138311,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000175544,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000163803,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000103966,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000073584,ENSG00000131188,ENSG00000139351,ENSG00000149591,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000170445,ENSG00000110090,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| TF:M11531 | Factor: E2F-2; motif: GCGCGCGCGYW | 0.0217240 | 13352 | 135 | 112 | 0.8296296 | 0.0083883 | TF | ENSG00000181588,ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000259316,ENSG00000179698,ENSG00000167967,ENSG00000172014,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000196569,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000100109,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000111641,ENSG00000186187,ENSG00000006459,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000170266,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000065970,ENSG00000164169,ENSG00000138311,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000141577,ENSG00000187051,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000188277,ENSG00000076321,ENSG00000088992,ENSG00000103966,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| TF:M08207_0 | Factor: E2F-3:TBR2; motif: ANGTGYKANGGCGCSTTNNCRNNT; match class: 0 | 0.0217240 | 17242 | 135 | 131 | 0.9703704 | 0.0075977 | TF | ENSG00000181588,ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000259316,ENSG00000179698,ENSG00000167967,ENSG00000146955,ENSG00000172014,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000196569,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000183963,ENSG00000188394,ENSG00000100109,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000112282,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000147443,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000156463,ENSG00000170266,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000185864,ENSG00000065970,ENSG00000011021,ENSG00000164169,ENSG00000138311,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000175544,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000188277,ENSG00000163803,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000105393,ENSG00000103966,ENSG00000116857,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000149591,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000110090,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| TF:M11531_0 | Factor: E2F-2; motif: GCGCGCGCGYW; match class: 0 | 0.0217240 | 13352 | 135 | 112 | 0.8296296 | 0.0083883 | TF | ENSG00000181588,ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000259316,ENSG00000179698,ENSG00000167967,ENSG00000172014,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000196569,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000100109,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000111641,ENSG00000186187,ENSG00000006459,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000170266,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000065970,ENSG00000164169,ENSG00000138311,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000141577,ENSG00000187051,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000188277,ENSG00000076321,ENSG00000088992,ENSG00000103966,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| TF:M01072_0 | Factor: HIC1; motif: NSNNNNTGCCCSSNN; match class: 0 | 0.0217240 | 4172 | 135 | 49 | 0.3629630 | 0.0117450 | TF | ENSG00000181588,ENSG00000136114,ENSG00000221916,ENSG00000179698,ENSG00000172014,ENSG00000147036,ENSG00000157954,ENSG00000169217,ENSG00000106991,ENSG00000254413,ENSG00000188229,ENSG00000197903,ENSG00000138448,ENSG00000168890,ENSG00000172059,ENSG00000112282,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000120318,ENSG00000116809,ENSG00000156463,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000065970,ENSG00000138311,ENSG00000167460,ENSG00000132613,ENSG00000168026,ENSG00000136044,ENSG00000128594,ENSG00000088992,ENSG00000103966,ENSG00000167703,ENSG00000215305,ENSG00000198742,ENSG00000153786,ENSG00000128309,ENSG00000137337,ENSG00000196123,ENSG00000188486,ENSG00000186834,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000163171,ENSG00000155252 |
| TF:M01072 | Factor: HIC1; motif: NSNNNNTGCCCSSNN | 0.0217240 | 4172 | 135 | 49 | 0.3629630 | 0.0117450 | TF | ENSG00000181588,ENSG00000136114,ENSG00000221916,ENSG00000179698,ENSG00000172014,ENSG00000147036,ENSG00000157954,ENSG00000169217,ENSG00000106991,ENSG00000254413,ENSG00000188229,ENSG00000197903,ENSG00000138448,ENSG00000168890,ENSG00000172059,ENSG00000112282,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000120318,ENSG00000116809,ENSG00000156463,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000065970,ENSG00000138311,ENSG00000167460,ENSG00000132613,ENSG00000168026,ENSG00000136044,ENSG00000128594,ENSG00000088992,ENSG00000103966,ENSG00000167703,ENSG00000215305,ENSG00000198742,ENSG00000153786,ENSG00000128309,ENSG00000137337,ENSG00000196123,ENSG00000188486,ENSG00000186834,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000163171,ENSG00000155252 |
| TF:M08207 | Factor: E2F-3:TBR2; motif: ANGTGYKANGGCGCSTTNNCRNNT | 0.0217240 | 17242 | 135 | 131 | 0.9703704 | 0.0075977 | TF | ENSG00000181588,ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000259316,ENSG00000179698,ENSG00000167967,ENSG00000146955,ENSG00000172014,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000196569,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000183963,ENSG00000188394,ENSG00000100109,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000112282,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000147443,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000156463,ENSG00000170266,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000185864,ENSG00000065970,ENSG00000011021,ENSG00000164169,ENSG00000138311,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000175544,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000188277,ENSG00000163803,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000105393,ENSG00000103966,ENSG00000116857,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000149591,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000110090,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| TF:M11022 | Factor: IRX2a; motif: ACRYGNNNNACRYGT | 0.0259577 | 9558 | 135 | 88 | 0.6518519 | 0.0092069 | TF | ENSG00000181588,ENSG00000198792,ENSG00000221916,ENSG00000179698,ENSG00000167967,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000130023,ENSG00000188092,ENSG00000088876,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000100109,ENSG00000141682,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000111641,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000120318,ENSG00000170266,ENSG00000154124,ENSG00000134901,ENSG00000070476,ENSG00000164169,ENSG00000167460,ENSG00000132613,ENSG00000141577,ENSG00000175544,ENSG00000198000,ENSG00000128594,ENSG00000163803,ENSG00000088992,ENSG00000197122,ENSG00000103966,ENSG00000116857,ENSG00000167703,ENSG00000144224,ENSG00000073584,ENSG00000177380,ENSG00000139351,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| TF:M11022_0 | Factor: IRX2a; motif: ACRYGNNNNACRYGT; match class: 0 | 0.0259577 | 9558 | 135 | 88 | 0.6518519 | 0.0092069 | TF | ENSG00000181588,ENSG00000198792,ENSG00000221916,ENSG00000179698,ENSG00000167967,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000130023,ENSG00000188092,ENSG00000088876,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000100109,ENSG00000141682,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000111641,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000120318,ENSG00000170266,ENSG00000154124,ENSG00000134901,ENSG00000070476,ENSG00000164169,ENSG00000167460,ENSG00000132613,ENSG00000141577,ENSG00000175544,ENSG00000198000,ENSG00000128594,ENSG00000163803,ENSG00000088992,ENSG00000197122,ENSG00000103966,ENSG00000116857,ENSG00000167703,ENSG00000144224,ENSG00000073584,ENSG00000177380,ENSG00000139351,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| TF:M08209_1 | Factor: E2F-3:FOXO6; motif: NAATGACACGCGCCCMC; match class: 1 | 0.0296277 | 7847 | 135 | 76 | 0.5629630 | 0.0096852 | TF | ENSG00000181588,ENSG00000136114,ENSG00000221916,ENSG00000259316,ENSG00000179698,ENSG00000172014,ENSG00000167550,ENSG00000147036,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000088876,ENSG00000254413,ENSG00000127824,ENSG00000111666,ENSG00000183963,ENSG00000141682,ENSG00000133131,ENSG00000163719,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000141854,ENSG00000176531,ENSG00000111641,ENSG00000006459,ENSG00000100284,ENSG00000119328,ENSG00000145020,ENSG00000120318,ENSG00000116809,ENSG00000156463,ENSG00000170266,ENSG00000137135,ENSG00000139977,ENSG00000070476,ENSG00000065970,ENSG00000011021,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000088992,ENSG00000103966,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000131188,ENSG00000139351,ENSG00000149591,ENSG00000129968,ENSG00000196338,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000186834,ENSG00000167378,ENSG00000109956,ENSG00000186654,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| TF:M00333_0 | Factor: ZF5; motif: NRNGNGCGCGCWN; match class: 0 | 0.0296277 | 15185 | 135 | 121 | 0.8962963 | 0.0079684 | TF | ENSG00000181588,ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000179698,ENSG00000167967,ENSG00000172014,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000196569,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000254413,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000183963,ENSG00000188394,ENSG00000100109,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000112282,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000156463,ENSG00000170266,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000065970,ENSG00000011021,ENSG00000164169,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000188277,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000105393,ENSG00000103966,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000149591,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000144395,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| TF:M00333 | Factor: ZF5; motif: NRNGNGCGCGCWN | 0.0296277 | 15185 | 135 | 121 | 0.8962963 | 0.0079684 | TF | ENSG00000181588,ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000179698,ENSG00000167967,ENSG00000172014,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000196569,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000254413,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000183963,ENSG00000188394,ENSG00000100109,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000112282,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000156463,ENSG00000170266,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000065970,ENSG00000011021,ENSG00000164169,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000188277,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000105393,ENSG00000103966,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000149591,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000144395,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| TF:M04515_0 | Factor: E2F-1; motif: WWTGGCGCCAAA; match class: 0 | 0.0384027 | 13432 | 135 | 111 | 0.8222222 | 0.0082638 | TF | ENSG00000181588,ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000259316,ENSG00000179698,ENSG00000167967,ENSG00000172014,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000196569,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000183963,ENSG00000100109,ENSG00000141682,ENSG00000077721,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000112282,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000147443,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000170266,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000011021,ENSG00000164169,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000188277,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000105393,ENSG00000103966,ENSG00000116857,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000149591,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000167378,ENSG00000151746,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000259431,ENSG00000112511 |
| TF:M04515 | Factor: E2F-1; motif: WWTGGCGCCAAA | 0.0384027 | 13432 | 135 | 111 | 0.8222222 | 0.0082638 | TF | ENSG00000181588,ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000259316,ENSG00000179698,ENSG00000167967,ENSG00000172014,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000196569,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000183963,ENSG00000100109,ENSG00000141682,ENSG00000077721,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000112282,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000147443,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000170266,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000011021,ENSG00000164169,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000188277,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000105393,ENSG00000103966,ENSG00000116857,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000149591,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000167378,ENSG00000151746,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000259431,ENSG00000112511 |
| TF:M01104_1 | Factor: MOVO-B; motif: GNGGGGG; match class: 1 | 0.0384027 | 5614 | 135 | 59 | 0.4370370 | 0.0105094 | TF | ENSG00000181588,ENSG00000198792,ENSG00000221916,ENSG00000147036,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000169217,ENSG00000188229,ENSG00000127824,ENSG00000138448,ENSG00000133131,ENSG00000077721,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000145569,ENSG00000112282,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000119328,ENSG00000120318,ENSG00000116809,ENSG00000154124,ENSG00000139977,ENSG00000134901,ENSG00000065970,ENSG00000138311,ENSG00000167460,ENSG00000132613,ENSG00000141577,ENSG00000136937,ENSG00000128594,ENSG00000088992,ENSG00000116857,ENSG00000167703,ENSG00000144224,ENSG00000142252,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000128309,ENSG00000170291,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000151746,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000259431,ENSG00000112511 |
| TF:M03567_1 | Factor: Sp2; motif: NYSGCCCCGCCCCCY; match class: 1 | 0.0388219 | 3618 | 135 | 43 | 0.3185185 | 0.0118850 | TF | ENSG00000181588,ENSG00000198792,ENSG00000167967,ENSG00000167550,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000169217,ENSG00000188229,ENSG00000138448,ENSG00000111666,ENSG00000183963,ENSG00000141682,ENSG00000077721,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000006459,ENSG00000120318,ENSG00000070476,ENSG00000167460,ENSG00000132613,ENSG00000141577,ENSG00000128594,ENSG00000088992,ENSG00000177380,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000148737,ENSG00000128309,ENSG00000198925,ENSG00000170291,ENSG00000186834,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000142634,ENSG00000259431,ENSG00000112511 |
| TF:M11601 | Factor: TCF-1; motif: ACATCGRGRCGCTGW | 0.0430208 | 14948 | 135 | 119 | 0.8814815 | 0.0079609 | TF | ENSG00000181588,ENSG00000198792,ENSG00000221916,ENSG00000179698,ENSG00000167967,ENSG00000172014,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000254413,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000183963,ENSG00000188394,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000112282,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000147443,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000156463,ENSG00000170266,ENSG00000154124,ENSG00000134901,ENSG00000070476,ENSG00000065970,ENSG00000011021,ENSG00000164169,ENSG00000138311,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000175544,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000188277,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000105393,ENSG00000103966,ENSG00000116857,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000149591,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000259431,ENSG00000112511 |
| TF:M11601_0 | Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 0 | 0.0430208 | 14948 | 135 | 119 | 0.8814815 | 0.0079609 | TF | ENSG00000181588,ENSG00000198792,ENSG00000221916,ENSG00000179698,ENSG00000167967,ENSG00000172014,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000254413,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000183963,ENSG00000188394,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000112282,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000147443,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000156463,ENSG00000170266,ENSG00000154124,ENSG00000134901,ENSG00000070476,ENSG00000065970,ENSG00000011021,ENSG00000164169,ENSG00000138311,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000175544,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000188277,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000105393,ENSG00000103966,ENSG00000116857,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000149591,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000259431,ENSG00000112511 |
| TF:M09817_1 | Factor: PAX5; motif: RNGCGTGACCNN; match class: 1 | 0.0430208 | 6202 | 135 | 63 | 0.4666667 | 0.0101580 | TF | ENSG00000181588,ENSG00000221916,ENSG00000179698,ENSG00000167967,ENSG00000080823,ENSG00000147036,ENSG00000196569,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000106991,ENSG00000088876,ENSG00000127824,ENSG00000111666,ENSG00000172273,ENSG00000141682,ENSG00000168890,ENSG00000172059,ENSG00000085377,ENSG00000176531,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000145020,ENSG00000120318,ENSG00000170266,ENSG00000154124,ENSG00000134901,ENSG00000011021,ENSG00000164169,ENSG00000167460,ENSG00000132613,ENSG00000141577,ENSG00000175544,ENSG00000198000,ENSG00000088992,ENSG00000105393,ENSG00000103966,ENSG00000167703,ENSG00000215305,ENSG00000131188,ENSG00000177380,ENSG00000149591,ENSG00000129968,ENSG00000198742,ENSG00000153786,ENSG00000128309,ENSG00000196123,ENSG00000147526,ENSG00000078804,ENSG00000167378,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000112511 |
| TF:M08526_1 | Factor: E2F-3:HES-7; motif: NNNSGCGCSNNNNNCRCGYGNN; match class: 1 | 0.0430208 | 15121 | 135 | 120 | 0.8888889 | 0.0079360 | TF | ENSG00000181588,ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000179698,ENSG00000167967,ENSG00000172014,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000183963,ENSG00000100109,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000156463,ENSG00000170266,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000065970,ENSG00000011021,ENSG00000164169,ENSG00000138311,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000175544,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000188277,ENSG00000088992,ENSG00000197122,ENSG00000105393,ENSG00000103966,ENSG00000116857,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000110090,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| TF:M08526_0 | Factor: E2F-3:HES-7; motif: NNNSGCGCSNNNNNCRCGYGNN; match class: 0 | 0.0439806 | 17026 | 135 | 129 | 0.9555556 | 0.0075766 | TF | ENSG00000181588,ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000179698,ENSG00000167967,ENSG00000146955,ENSG00000172014,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000196569,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000254413,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000183963,ENSG00000188394,ENSG00000100109,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000112282,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000147443,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000156463,ENSG00000170266,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000065970,ENSG00000011021,ENSG00000164169,ENSG00000138311,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000175544,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000188277,ENSG00000163803,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000105393,ENSG00000103966,ENSG00000116857,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000110090,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| TF:M08526 | Factor: E2F-3:HES-7; motif: NNNSGCGCSNNNNNCRCGYGNN | 0.0439806 | 17026 | 135 | 129 | 0.9555556 | 0.0075766 | TF | ENSG00000181588,ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000179698,ENSG00000167967,ENSG00000146955,ENSG00000172014,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000196569,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000254413,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000183963,ENSG00000188394,ENSG00000100109,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000112282,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000147443,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000156463,ENSG00000170266,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000065970,ENSG00000011021,ENSG00000164169,ENSG00000138311,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000175544,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000188277,ENSG00000163803,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000105393,ENSG00000103966,ENSG00000116857,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000110090,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| TF:M09636 | Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG | 0.0439806 | 16373 | 135 | 126 | 0.9333333 | 0.0076956 | TF | ENSG00000181588,ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000179698,ENSG00000167967,ENSG00000146955,ENSG00000172014,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000196569,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000254413,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000178878,ENSG00000183963,ENSG00000188394,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000112282,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000147443,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000170266,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000065970,ENSG00000011021,ENSG00000164169,ENSG00000138311,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000175544,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000188277,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000105393,ENSG00000103966,ENSG00000116857,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000149591,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| TF:M09636_0 | Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG; match class: 0 | 0.0439806 | 16373 | 135 | 126 | 0.9333333 | 0.0076956 | TF | ENSG00000181588,ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000179698,ENSG00000167967,ENSG00000146955,ENSG00000172014,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000196569,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000088876,ENSG00000254413,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000178878,ENSG00000183963,ENSG00000188394,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000112282,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000147443,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000170266,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000065970,ENSG00000011021,ENSG00000164169,ENSG00000138311,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000175544,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000188277,ENSG00000076321,ENSG00000088992,ENSG00000197122,ENSG00000105393,ENSG00000103966,ENSG00000116857,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000149591,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| TF:M07039_1 | Factor: ETF; motif: CCCCGCCCCYN; match class: 1 | 0.0439806 | 13706 | 135 | 112 | 0.8296296 | 0.0081716 | TF | ENSG00000181588,ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000179698,ENSG00000167967,ENSG00000172014,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188092,ENSG00000106991,ENSG00000254413,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000183963,ENSG00000188394,ENSG00000100109,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000111641,ENSG00000196547,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000145020,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000170266,ENSG00000154124,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000065970,ENSG00000011021,ENSG00000164169,ENSG00000138311,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000187051,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000088992,ENSG00000197122,ENSG00000103966,ENSG00000116857,ENSG00000167703,ENSG00000215305,ENSG00000142252,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000149591,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000142634,ENSG00000145029,ENSG00000259431,ENSG00000112511 |
| TF:M04869_1 | Factor: Egr-1; motif: GCGCATGCG; match class: 1 | 0.0440506 | 10295 | 135 | 91 | 0.6740741 | 0.0088392 | TF | ENSG00000181588,ENSG00000198792,ENSG00000221916,ENSG00000179698,ENSG00000167967,ENSG00000172014,ENSG00000080823,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000088876,ENSG00000188229,ENSG00000127824,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000172273,ENSG00000141682,ENSG00000133131,ENSG00000077721,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000166813,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000176531,ENSG00000111641,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000170266,ENSG00000154124,ENSG00000137135,ENSG00000070476,ENSG00000065970,ENSG00000164169,ENSG00000138311,ENSG00000167460,ENSG00000132613,ENSG00000187051,ENSG00000136937,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000088992,ENSG00000103966,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000142252,ENSG00000073584,ENSG00000177380,ENSG00000139351,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000153786,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000196123,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000078804,ENSG00000167378,ENSG00000151746,ENSG00000170445,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000155252,ENSG00000115266,ENSG00000112511 |
| TF:M00008_1 | Factor: Sp1; motif: GGGGCGGGGT; match class: 1 | 0.0440506 | 4946 | 135 | 53 | 0.3925926 | 0.0107157 | TF | ENSG00000181588,ENSG00000172014,ENSG00000167550,ENSG00000120913,ENSG00000160072,ENSG00000106009,ENSG00000169217,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000138448,ENSG00000111666,ENSG00000141682,ENSG00000077721,ENSG00000163719,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000145569,ENSG00000176531,ENSG00000186187,ENSG00000006459,ENSG00000184047,ENSG00000120318,ENSG00000170266,ENSG00000134901,ENSG00000070476,ENSG00000011021,ENSG00000138311,ENSG00000167460,ENSG00000141577,ENSG00000168026,ENSG00000128594,ENSG00000088992,ENSG00000103966,ENSG00000167703,ENSG00000215305,ENSG00000177380,ENSG00000149591,ENSG00000145911,ENSG00000198742,ENSG00000148737,ENSG00000153786,ENSG00000128309,ENSG00000137337,ENSG00000170291,ENSG00000196123,ENSG00000186834,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000142634 |
| TF:M04516_0 | Factor: E2F-1; motif: TTTGGCGCCAAA; match class: 0 | 0.0491274 | 11432 | 135 | 98 | 0.7259259 | 0.0085724 | TF | ENSG00000181588,ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000259316,ENSG00000179698,ENSG00000167967,ENSG00000172014,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000196569,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000183963,ENSG00000100109,ENSG00000141682,ENSG00000077721,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000112282,ENSG00000111641,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000147443,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000170266,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000011021,ENSG00000164169,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000076321,ENSG00000197122,ENSG00000103966,ENSG00000116857,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000149591,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000151746,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000115266,ENSG00000142634,ENSG00000259431,ENSG00000112511 |
| TF:M04516 | Factor: E2F-1; motif: TTTGGCGCCAAA | 0.0491274 | 11432 | 135 | 98 | 0.7259259 | 0.0085724 | TF | ENSG00000181588,ENSG00000136114,ENSG00000198792,ENSG00000221916,ENSG00000259316,ENSG00000179698,ENSG00000167967,ENSG00000172014,ENSG00000167202,ENSG00000167550,ENSG00000147036,ENSG00000196569,ENSG00000027001,ENSG00000120913,ENSG00000160072,ENSG00000157954,ENSG00000106009,ENSG00000130023,ENSG00000169217,ENSG00000188229,ENSG00000127824,ENSG00000186281,ENSG00000197903,ENSG00000138448,ENSG00000111666,ENSG00000183963,ENSG00000100109,ENSG00000141682,ENSG00000077721,ENSG00000168890,ENSG00000204316,ENSG00000172059,ENSG00000145569,ENSG00000085377,ENSG00000141854,ENSG00000112282,ENSG00000111641,ENSG00000186187,ENSG00000006459,ENSG00000100284,ENSG00000184047,ENSG00000119328,ENSG00000147443,ENSG00000120318,ENSG00000116809,ENSG00000086289,ENSG00000170266,ENSG00000154124,ENSG00000137135,ENSG00000139977,ENSG00000134901,ENSG00000070476,ENSG00000011021,ENSG00000164169,ENSG00000152253,ENSG00000167460,ENSG00000132613,ENSG00000132334,ENSG00000141577,ENSG00000168026,ENSG00000136044,ENSG00000198000,ENSG00000128594,ENSG00000076321,ENSG00000197122,ENSG00000103966,ENSG00000116857,ENSG00000167703,ENSG00000215305,ENSG00000144224,ENSG00000073584,ENSG00000131188,ENSG00000177380,ENSG00000139351,ENSG00000149591,ENSG00000129968,ENSG00000145911,ENSG00000198742,ENSG00000196338,ENSG00000148737,ENSG00000128309,ENSG00000198925,ENSG00000137337,ENSG00000156256,ENSG00000170291,ENSG00000147526,ENSG00000188486,ENSG00000186834,ENSG00000151746,ENSG00000196586,ENSG00000109956,ENSG00000186654,ENSG00000167799,ENSG00000163171,ENSG00000115266,ENSG00000142634,ENSG00000259431,ENSG00000112511 |
99 downregulated genesets are returned from CORUM, GO, and TRANSFAC.
No unifying biological themes were found in these genesets.
Treatment Cycle 3 vs Pre-Treatment
# First divide the list into upregulated and downregulated genes
Cycle3.vs.PreTreat %>% distinct(external_gene_name, .keep_all = TRUE) -> Cycle3.vs.PreTreat
Cycle3.vs.PreTreat %>% filter(logFC > 0 & P.Value < 0.05) -> Up_Regulated_Cycle3.vs.PreTreat
Cycle3.vs.PreTreat %>% filter(logFC < 0 & P.Value < 0.05) -> Down_Regulated_Cycle3.vs.PreTreat
if(!all(c("upreg_genelist_cycle3_pretreat_ensembl", "downreg_genelist_cycle3_pretreat_ensembl","cycle3_pretreat_Whole_gene")
%in% ls())){
upreg_genelist_cycle3_pretreat_ensembl <- gost(query = Up_Regulated_Cycle3.vs.PreTreat$ensembl_gene_id,
organism = "hsapiens", evcodes = TRUE, user_threshold = 0.05, correction_method = "fdr")
downreg_genelist_cycle3_pretreat_ensembl <- gost(query = Down_Regulated_Cycle3.vs.PreTreat$ensembl_gene_id,
organism = "hsapiens", evcodes = TRUE, user_threshold = 0.05,
correction_method = "fdr")
cycle3_pretreat_Whole_gene <- gost(query = Cycle3.vs.PreTreat$ensembl_gene_id,
organism = "hsapiens", evcodes = TRUE, user_threshold = 0.05,
correction_method = "fdr")
}Upregulated genes with BH FDR correction < 0.05
result.up.cycle3_pretreat <- upreg_genelist_cycle3_pretreat_ensembl$result
result.up.cycle3_pretreat <- result.up.cycle3_pretreat %>% dplyr::select(c(3:16)) %>% subset(select=c(7,9, 1:6,8, 14))
# nrow(result.up.cycle3_pretreat)
kable(result.up.cycle3_pretreat) %>%
kable_styling() %>%
scroll_box(width = "800px", height = "500px")| term_id | term_name | p_value | term_size | query_size | intersection_size | precision | recall | source | intersection |
|---|---|---|---|---|---|---|---|---|---|
| CORUM:2406 | ITGA3-ITGB1 complex | 0.0295375 | 2 | 20 | 1 | 0.05 | 0.5000000 | CORUM | ENSG00000005884 |
| CORUM:2399 | ITGA3-ITGB1-CD63 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000005884 |
| CORUM:2400 | ITGA3-ITGB1-CD151 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000005884 |
| CORUM:2401 | ITGA3-ITGB1-THBS1 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000005884 |
| CORUM:7104 | NBS1–RNF8-VRK1 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000112130 |
| CORUM:2436 | ITGAV-ITGB1 complex | 0.0295375 | 2 | 20 | 1 | 0.05 | 0.5000000 | CORUM | ENSG00000138448 |
| CORUM:2593 | FOXO3-SIRT1 complex, oxidative stress stimulated | 0.0295375 | 2 | 20 | 1 | 0.05 | 0.5000000 | CORUM | ENSG00000118689 |
| CORUM:2678 | FOXO3-TP53 complex, oxidative stress stimulated | 0.0295375 | 2 | 20 | 1 | 0.05 | 0.5000000 | CORUM | ENSG00000118689 |
| CORUM:2734 | APH1A-PSEN1-NCSTN complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000117362 |
| CORUM:2735 | APH1A-PSEN2-NCSTN complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000117362 |
| CORUM:2760 | SMAD3-SMAD4-FOXO3 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000118689 |
| CORUM:2816 | ITGAV-ITGB3 complex | 0.0295375 | 2 | 20 | 1 | 0.05 | 0.5000000 | CORUM | ENSG00000138448 |
| CORUM:2826 | ITGB3-ITGAV-VTN complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:2846 | ITGAV-ITGB3-THBS1 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:2849 | ITGAV-ITGB3-NOV complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:2885 | ITGAV-ITGB1-SPP1 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:3103 | ITGAV-ITGB3-SLC3A2 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:3110 | ITGAV-P2RY2-GNA12 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:3117 | ITGB5-ITGAV-VTN complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:3150 | NK-3-Groucho complex | 0.0295375 | 2 | 20 | 1 | 0.05 | 0.5000000 | CORUM | ENSG00000167034 |
| CORUM:3544 | COG2-COG3-COG4 subcomplex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000136152 |
| CORUM:4478 | CBF-DNA complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000120837 |
| CORUM:6061 | DISC1-ZNF365 complex | 0.0295375 | 2 | 20 | 1 | 0.05 | 0.5000000 | CORUM | ENSG00000138311 |
| CORUM:6493 | CUL4A-DDB1-WDR57 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000060688 |
| CORUM:6590 | FOXO3-CBP complex | 0.0295375 | 2 | 20 | 1 | 0.05 | 0.5000000 | CORUM | ENSG00000118689 |
| CORUM:6993 | FGF1-ITGAV-ITGB3 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:2398 | ITGA3-ITGB1-BSG complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000005884 |
| CORUM:2374 | ITGAV-ITGB3-LAMA4 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:7587 | APP(AICD)-FOXO3 complex | 0.0295375 | 2 | 20 | 1 | 0.05 | 0.5000000 | CORUM | ENSG00000118689 |
| CORUM:2369 | ITGAV-ITGB3-EGFR complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:1338 | FOXO3-PCAF complex, oxidative stress stimulated | 0.0295375 | 2 | 20 | 1 | 0.05 | 0.5000000 | CORUM | ENSG00000118689 |
| CORUM:2342 | ITGAV-ITGB8-MMP14-TGFB1 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:2343 | ITGAV-ITGB5-PLAUR complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:2373 | ITGAV-ITGB3-SPP1 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:2346 | ITGAV-ITGB5-ADAM9 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:2347 | ITGAV-ITGB5-SPP1 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:2348 | ITGAV-ITGB5-CYR61 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:2350 | ITGAV-ITGB5 complex | 0.0295375 | 2 | 20 | 1 | 0.05 | 0.5000000 | CORUM | ENSG00000138448 |
| CORUM:2352 | ITGAV-ITGB6-SPP1 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:2353 | ITGAV-ITGB6-TGFB3 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:2345 | ITGAV-ITGB5-ICAM4 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:2356 | ITGB3-ITGAV-CD47 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:2358 | ITGAV-ITGB3-SPP1 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:2359 | ITGAV-ITGB3-ADAM15 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:2362 | ITAGV-ITGB3-F11R complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:2364 | ITGAV-ITGB3-ADAM23 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:2365 | ITGAV-ITGB3-COL4A3 complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:2366 | ITGAV-ITGB3-PPAP2b complex | 0.0295375 | 3 | 20 | 1 | 0.05 | 0.3333333 | CORUM | ENSG00000138448 |
| CORUM:2354 | ITGAV-ITGB6 complex | 0.0295375 | 2 | 20 | 1 | 0.05 | 0.5000000 | CORUM | ENSG00000138448 |
| CORUM:2355 | ITGAV-ITGB3-CD47-FCER2 complex | 0.0310442 | 4 | 20 | 1 | 0.05 | 0.2500000 | CORUM | ENSG00000138448 |
| CORUM:45 | Gamma-secretase complex (APH1A, PSEN1, PSENEN, NCSTN) | 0.0310442 | 4 | 20 | 1 | 0.05 | 0.2500000 | CORUM | ENSG00000117362 |
| CORUM:6990 | THSD1-FAK-talin-vinculin complex | 0.0310442 | 4 | 20 | 1 | 0.05 | 0.2500000 | CORUM | ENSG00000136114 |
| CORUM:6951 | NG2-galectin-3-alpha3beta1-integrin complex | 0.0310442 | 4 | 20 | 1 | 0.05 | 0.2500000 | CORUM | ENSG00000005884 |
| CORUM:127 | NDC80 kinetochore complex | 0.0310442 | 4 | 20 | 1 | 0.05 | 0.2500000 | CORUM | ENSG00000152253 |
| CORUM:6193 | ADAM12-alphaVbeta3-integrin-MMP-14 complex | 0.0310442 | 4 | 20 | 1 | 0.05 | 0.2500000 | CORUM | ENSG00000138448 |
| CORUM:4498 | p32-CBF-DNA complex | 0.0310442 | 4 | 20 | 1 | 0.05 | 0.2500000 | CORUM | ENSG00000120837 |
| CORUM:468 | Gamma-secretase complex (APH1A, PSEN2, PSENEN, NCSTN) | 0.0310442 | 4 | 20 | 1 | 0.05 | 0.2500000 | CORUM | ENSG00000117362 |
| CORUM:2363 | ITGAV-ITGB3-PXN-PTK2b complex | 0.0310442 | 4 | 20 | 1 | 0.05 | 0.2500000 | CORUM | ENSG00000138448 |
| CORUM:2891 | Gamma-secretase complex (APH1A, PSEN1, PSENEN, NCSTN) | 0.0310442 | 4 | 20 | 1 | 0.05 | 0.2500000 | CORUM | ENSG00000117362 |
| CORUM:2707 | SMAD3-SMAD4-FOXO3-FOXG1 complex | 0.0310442 | 4 | 20 | 1 | 0.05 | 0.2500000 | CORUM | ENSG00000118689 |
| CORUM:466 | Gamma-secretase complex (APH1A, PSEN1, PSENEN, NCSTN) | 0.0310442 | 4 | 20 | 1 | 0.05 | 0.2500000 | CORUM | ENSG00000117362 |
| CORUM:43 | Gamma-secretase complex (APH1A, PSEN1, PSENEN, NCSTN) | 0.0310442 | 4 | 20 | 1 | 0.05 | 0.2500000 | CORUM | ENSG00000117362 |
| CORUM:3551 | COG1-COG8-COG2-COG3-COG4 subcomplex | 0.0363581 | 5 | 20 | 1 | 0.05 | 0.2000000 | CORUM | ENSG00000136152 |
| CORUM:5975 | Gamma-secretase complex (APH1A, PSENEN, PSEN1, NCSTN, TMP21) | 0.0363581 | 5 | 20 | 1 | 0.05 | 0.2000000 | CORUM | ENSG00000117362 |
| CORUM:3271 | Gamma-secretase-Delta1 complex | 0.0363581 | 5 | 20 | 1 | 0.05 | 0.2000000 | CORUM | ENSG00000117362 |
| CORUM:142 | CD147-gamma-secretase complex | 0.0363581 | 5 | 20 | 1 | 0.05 | 0.2000000 | CORUM | ENSG00000117362 |
| CORUM:324 | 39S ribosomal subunit, mitochondrial | 0.0367422 | 48 | 20 | 2 | 0.10 | 0.0416667 | CORUM | ENSG00000171421,ENSG00000136522 |
| CORUM:3149 | NK-3-Groucho-HIPK2-SIN3A-RbpA48-HDAC1 complex | 0.0422360 | 6 | 20 | 1 | 0.05 | 0.1666667 | CORUM | ENSG00000167034 |
| CORUM:6255 | MICOS complex | 0.0484344 | 7 | 20 | 1 | 0.05 | 0.1428571 | CORUM | ENSG00000184831 |
71 upregulated genesets are returned from CORUM and GO.
No unifying biological theme was found in this analysis.
Downregulated genes with BH FDR correction < 0.05
result.down.cycle3_pretreat <- downreg_genelist_cycle3_pretreat_ensembl$result
result.down.cycle3_pretreat <- result.down.cycle3_pretreat %>% dplyr::select(c(3:16)) %>% subset(select=c(7,9, 1:6,8, 14))
# nrow(result.down.cycle3_pretreat)
kable(result.down.cycle3_pretreat) %>%
kable_styling() %>%
scroll_box(width = "800px", height = "500px")| term_id | term_name | p_value | term_size | query_size | intersection_size | precision | recall | source | intersection |
|---|---|---|---|---|---|---|---|---|---|
| CORUM:4039 | PAR4-BACE1 complex | 0.0033571 | 2 | 26 | 2 | 0.0769231 | 1.0000000 | CORUM | ENSG00000177425,ENSG00000186318 |
| CORUM:6956 | REP-RGGT-Rab complex | 0.0050135 | 3 | 26 | 2 | 0.0769231 | 0.6666667 | CORUM | ENSG00000188419,ENSG00000105649 |
| CORUM:5143 | RB-E2F1 complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000101412 |
| CORUM:7588 | APP(AICD)-FOXO1 complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000142192 |
| CORUM:5370 | ERAP1-ERAP2 complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000164308 |
| CORUM:5542 | CCNB2-CDC2 complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000157456 |
| CORUM:5830 | DJ-1-SNCA complex, high molecular weight complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000145335 |
| CORUM:6056 | APP-TNFRSF21 complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000142192 |
| CORUM:6437 | GABBR1-GABBR2 complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000204681 |
| CORUM:6588 | E2F-1-DP-1 complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000101412 |
| CORUM:6615 | SPG4-SPG12 complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000125744 |
| CORUM:6624 | MGAT4B-SLC35A3 complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000161013 |
| CORUM:6625 | MGAT4B-SLC35A2(splice variant 1) complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000161013 |
| CORUM:7241 | SNCA-TUBB3 complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000145335 |
| CORUM:7486 | HAS2-HAS3 | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000103044 |
| CORUM:7529 | APP-Abeta42-VDAC1 complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000142192 |
| CORUM:7574 | APP-PSEN1 complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000142192 |
| CORUM:7575 | APP-PSEN2 complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000142192 |
| CORUM:7579 | APP(AICD)-MED12 complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000142192 |
| CORUM:7587 | APP(AICD)-FOXO3 complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000142192 |
| CORUM:3124 | TLE1-TLE2 complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000065717 |
| CORUM:3123 | TLE2 homodimer complex | 0.0334833 | 1 | 26 | 1 | 0.0384615 | 1.0000000 | CORUM | ENSG00000065717 |
| CORUM:7589 | APP(AICD)-FOXO4 complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000142192 |
| CORUM:3092 | APP-TOM40 complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000142192 |
| CORUM:2943 | Respiratory chain complex I (incomplete NDUFAF1 assembly), mitochondrial | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000137806 |
| CORUM:1250 | RB-E2F1 complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000101412 |
| CORUM:2003 | COX1 homodimer complex | 0.0334833 | 1 | 26 | 1 | 0.0384615 | 1.0000000 | CORUM | ENSG00000095303 |
| CORUM:3093 | APP-TIM23 complex | 0.0334833 | 2 | 26 | 1 | 0.0384615 | 0.5000000 | CORUM | ENSG00000142192 |
| CORUM:2711 | Amyloid beta protein homo-oligomer complex | 0.0334833 | 1 | 26 | 1 | 0.0384615 | 1.0000000 | CORUM | ENSG00000142192 |
| CORUM:120 | Lymphotoxin beta receptor complex | 0.0337561 | 3 | 26 | 1 | 0.0384615 | 0.3333333 | CORUM | ENSG00000227507 |
| CORUM:143 | APP-APBB1-LRP1 complex | 0.0337561 | 3 | 26 | 1 | 0.0384615 | 0.3333333 | CORUM | ENSG00000142192 |
| CORUM:7577 | APP-APBB1-KAT5 complex | 0.0337561 | 3 | 26 | 1 | 0.0384615 | 0.3333333 | CORUM | ENSG00000142192 |
| CORUM:2693 | NFAT-JUN-FOS DNA-protein complex | 0.0337561 | 3 | 26 | 1 | 0.0384615 | 0.3333333 | CORUM | ENSG00000170345 |
| CORUM:2694 | ERG-JUN-FOS DNA-protein complex | 0.0337561 | 3 | 26 | 1 | 0.0384615 | 0.3333333 | CORUM | ENSG00000170345 |
| CORUM:6487 | CUL4B-DDB1-TLE2 complex | 0.0337561 | 3 | 26 | 1 | 0.0384615 | 0.3333333 | CORUM | ENSG00000065717 |
| CORUM:2695 | ETS2-FOS-JUN complex | 0.0337561 | 3 | 26 | 1 | 0.0384615 | 0.3333333 | CORUM | ENSG00000170345 |
| CORUM:5805 | PGAM5-KEAP1-NRF2 complex | 0.0337561 | 3 | 26 | 1 | 0.0384615 | 0.3333333 | CORUM | ENSG00000116044 |
| CORUM:5656 | CEBPE-E2F1-RB1 complex | 0.0337561 | 3 | 26 | 1 | 0.0384615 | 0.3333333 | CORUM | ENSG00000101412 |
| CORUM:2942 | Ecsit complex (ECSIT, NDUFS3, NDUFAF1) | 0.0337561 | 3 | 26 | 1 | 0.0384615 | 0.3333333 | CORUM | ENSG00000137806 |
| CORUM:5144 | E2F1-p107-cyclinA complex | 0.0337561 | 3 | 26 | 1 | 0.0384615 | 0.3333333 | CORUM | ENSG00000101412 |
| CORUM:3900 | GABP(gamma)1-E2F1-DP1 complex | 0.0337561 | 3 | 26 | 1 | 0.0384615 | 0.3333333 | CORUM | ENSG00000101412 |
| CORUM:6235 | c-Fos-c-Jun-SAF-1 complex | 0.0337561 | 3 | 26 | 1 | 0.0384615 | 0.3333333 | CORUM | ENSG00000170345 |
| CORUM:74 | HOMER3-IP3R-TRPC1 complex | 0.0337561 | 3 | 26 | 1 | 0.0384615 | 0.3333333 | CORUM | ENSG00000051128 |
| CORUM:6589 | E2F-1-DP-1-cyclinA-CDK2 complex | 0.0401811 | 4 | 26 | 1 | 0.0384615 | 0.2500000 | CORUM | ENSG00000101412 |
| CORUM:2886 | Respiratory chain complex I (incomplete intermediate ND1, ND2, ND3, CIA30 assembly), mitochondrial | 0.0401811 | 4 | 26 | 1 | 0.0384615 | 0.2500000 | CORUM | ENSG00000137806 |
| CORUM:2692 | SMAD3-SMAD4-cJun-cFos complex | 0.0401811 | 4 | 26 | 1 | 0.0384615 | 0.2500000 | CORUM | ENSG00000170345 |
| CORUM:1488 | DNMT1-RB1-HDAC1-E2F1 complex | 0.0401811 | 4 | 26 | 1 | 0.0384615 | 0.2500000 | CORUM | ENSG00000101412 |
| CORUM:678 | GINS complex | 0.0401811 | 4 | 26 | 1 | 0.0384615 | 0.2500000 | CORUM | ENSG00000181938 |
| CORUM:2810 | RAD17-RFC complex | 0.0462035 | 5 | 26 | 1 | 0.0384615 | 0.2000000 | CORUM | ENSG00000152942 |
| CORUM:2936 | Ecsit complex (ECSIT, MT-CO2, GAPDH, TRAF6, NDUFAF1) | 0.0462035 | 5 | 26 | 1 | 0.0384615 | 0.2000000 | CORUM | ENSG00000137806 |
| CORUM:270 | RAD17-RFC complex | 0.0462035 | 5 | 26 | 1 | 0.0384615 | 0.2000000 | CORUM | ENSG00000152942 |
| CORUM:266 | RAD17-RFC complex | 0.0462035 | 5 | 26 | 1 | 0.0384615 | 0.2000000 | CORUM | ENSG00000152942 |
| GO:0008021 | synaptic vesicle | 0.0308064 | 213 | 136 | 8 | 0.0588235 | 0.0375587 | GO:CC | ENSG00000186318,ENSG00000145335,ENSG00000087053,ENSG00000142192,ENSG00000067836,ENSG00000167371,ENSG00000105649,ENSG00000104093 |
| GO:0043291 | RAVE complex | 0.0308064 | 3 | 136 | 2 | 0.0147059 | 0.6666667 | GO:CC | ENSG00000067836,ENSG00000104093 |
| GO:0070382 | exocytic vesicle | 0.0336163 | 229 | 136 | 8 | 0.0588235 | 0.0349345 | GO:CC | ENSG00000186318,ENSG00000145335,ENSG00000087053,ENSG00000142192,ENSG00000067836,ENSG00000167371,ENSG00000105649,ENSG00000104093 |
55 downregulated genesets are returned from CORUM and GO.
No unifying biological theme was found in this analysis.
Patient B vs Patient C
# First divide the list into upregulated and downregulated genes
PatientB.vs.PatientC %>% distinct(external_gene_name, .keep_all = TRUE) -> PatientB.vs.PatientC
PatientB.vs.PatientC %>% filter(logFC > 0 & P.Value < 0.05) -> Up_Regulated_PatientB.vs.PatientC
PatientB.vs.PatientC %>% filter(logFC < 0 & P.Value < 0.05) -> Down_Regulated_PatientB.vs.PatientC
if(!all(c("upreg_genelist_B_C_ensembl","downreg_genelist_B_C_ensembl","B_C_Whole_gene") %in% ls())){
upreg_genelist_B_C_ensembl <- gost(query = Up_Regulated_PatientB.vs.PatientC$ensembl_gene_id,
organism = "hsapiens", evcodes = TRUE, user_threshold = 0.01, correction_method = "fdr",
sources = c("GO", "KEGG", "REAC", "MIRAN", "CORUM", "WP"))
downreg_genelist_B_C_ensembl <- gost(query = Down_Regulated_PatientB.vs.PatientC$ensembl_gene_id,
organism = "hsapiens", evcodes = TRUE, user_threshold = 0.01,
correction_method = "fdr",
sources = c("GO", "KEGG", "REAC", "MIRAN", "CORUM", "WP"))
B_C_Whole_gene <- gost(query = PatientB.vs.PatientC$ensembl_gene_id,
organism = "hsapiens", evcodes = TRUE, user_threshold = 0.01,
correction_method = "fdr",
sources = c("GO", "KEGG", "REAC", "MIRAN", "CORUM", "WP"))
}Upregulated genes with BH FDR correction < 0.01
result.up.B_C <- upreg_genelist_B_C_ensembl$result
result.up.B_C <- result.up.B_C %>% dplyr::select(c(3:16)) %>% subset(select=c(7,9, 1:6,8, 14))
kable(result.up.B_C) %>% kable_styling() %>%
scroll_box(width = "800px", height = "500px")| term_id | term_name | p_value | term_size | query_size | intersection_size | precision | recall | source | intersection |
|---|---|---|---|---|---|---|---|---|---|
| GO:0005794 | Golgi apparatus | 0.0001493 | 1586 | 647 | 93 | 0.1437403 | 0.0586381 | GO:CC | ENSG00000151150,ENSG00000038427,ENSG00000111962,ENSG00000008256,ENSG00000224051,ENSG00000116106,ENSG00000164300,ENSG00000152127,ENSG00000139044,ENSG00000136935,ENSG00000013619,ENSG00000175265,ENSG00000135074,ENSG00000123384,ENSG00000154265,ENSG00000171368,ENSG00000107611,ENSG00000163435,ENSG00000130956,ENSG00000111817,ENSG00000135636,ENSG00000127946,ENSG00000145730,ENSG00000039068,ENSG00000166377,ENSG00000153214,ENSG00000164056,ENSG00000154917,ENSG00000070731,ENSG00000087085,ENSG00000167207,ENSG00000198168,ENSG00000070718,ENSG00000213930,ENSG00000182272,ENSG00000137642,ENSG00000163820,ENSG00000100311,ENSG00000138834,ENSG00000090905,ENSG00000174749,ENSG00000174130,ENSG00000197249,ENSG00000166405,ENSG00000087502,ENSG00000168237,ENSG00000119820,ENSG00000163235,ENSG00000176597,ENSG00000177054,ENSG00000178104,ENSG00000168461,ENSG00000165029,ENSG00000007516,ENSG00000120708,ENSG00000165905,ENSG00000135052,ENSG00000175106,ENSG00000168824,ENSG00000101246,ENSG00000106003,ENSG00000181704,ENSG00000175054,ENSG00000162852,ENSG00000100314,ENSG00000157227,ENSG00000101236,ENSG00000154764,ENSG00000187240,ENSG00000143226,ENSG00000111666,ENSG00000152056,ENSG00000122126,ENSG00000127914,ENSG00000262246,ENSG00000184307,ENSG00000129219,ENSG00000166086,ENSG00000135218,ENSG00000099910,ENSG00000125149,ENSG00000203879,ENSG00000124164,ENSG00000142687,ENSG00000103502,ENSG00000138604,ENSG00000119514,ENSG00000134262,ENSG00000196367,ENSG00000143919,ENSG00000067141,ENSG00000206077,ENSG00000196352 |
| GO:0005085 | guanyl-nucleotide exchange factor activity | 0.0077091 | 224 | 634 | 22 | 0.0347003 | 0.0982143 | GO:MF | ENSG00000038382,ENSG00000008256,ENSG00000125731,ENSG00000116641,ENSG00000134215,ENSG00000133812,ENSG00000101977,ENSG00000205726,ENSG00000116191,ENSG00000088538,ENSG00000119979,ENSG00000174485,ENSG00000257093,ENSG00000100485,ENSG00000177963,ENSG00000053524,ENSG00000136002,ENSG00000155849,ENSG00000115211,ENSG00000152689,ENSG00000104728,ENSG00000160271 |
| GO:0051020 | GTPase binding | 0.0077091 | 551 | 634 | 40 | 0.0630915 | 0.0725953 | GO:MF | ENSG00000038382,ENSG00000008256,ENSG00000089177,ENSG00000125731,ENSG00000116641,ENSG00000134215,ENSG00000130396,ENSG00000133812,ENSG00000101977,ENSG00000205726,ENSG00000243156,ENSG00000135127,ENSG00000116191,ENSG00000137942,ENSG00000025039,ENSG00000137501,ENSG00000088538,ENSG00000117016,ENSG00000141258,ENSG00000119979,ENSG00000174485,ENSG00000167291,ENSG00000257093,ENSG00000100485,ENSG00000137642,ENSG00000177963,ENSG00000104093,ENSG00000053524,ENSG00000165029,ENSG00000136002,ENSG00000155849,ENSG00000115211,ENSG00000161835,ENSG00000152689,ENSG00000122126,ENSG00000153165,ENSG00000104728,ENSG00000203879,ENSG00000065243,ENSG00000160271 |
| KEGG:04015 | Rap1 signaling pathway | 0.0046256 | 210 | 277 | 21 | 0.0758123 | 0.1000000 | KEGG | ENSG00000117020,ENSG00000077782,ENSG00000134215,ENSG00000182621,ENSG00000130396,ENSG00000037280,ENSG00000102678,ENSG00000156052,ENSG00000039068,ENSG00000120318,ENSG00000167193,ENSG00000197122,ENSG00000051382,ENSG00000197555,ENSG00000100311,ENSG00000081026,ENSG00000112062,ENSG00000152689,ENSG00000070087,ENSG00000184574,ENSG00000160271 |
4 upregulated genesets are returned, from GO and KEGG.
No unifying biological theme was found in this analysis.
Downregulated genes with BH FDR correction < 0.01
result.down.B_C <- downreg_genelist_B_C_ensembl$result
result.down.B_C <- result.down.B_C %>% dplyr::select(c(3:16)) %>% subset(select=c(7,9, 1:6,8, 14))
# nrow(result.down.B_C)
PD.1.index <- grep(x = result.down.B_C$term_name, pattern = "PD-1")
IL12.index <- grep(x = result.down.B_C$term_name, pattern = "interleukin-12", ignore.case = TRUE)
costim.index <- grep(x = result.down.B_C$term_name, pattern = "costim", ignore.case = TRUE)
interferon.gamma.index <- grep(x = result.down.B_C$term_name, pattern = "gamma", ignore.case = TRUE)
TCR.index <- grep(x = result.down.B_C$term_name, pattern = "TCR", ignore.case = TRUE)
# https://haozhu233.github.io/kableExtra/awesome_table_in_html.html
kable(result.down.B_C) %>%
kable_styling() %>%
row_spec(row = c(interferon.gamma.index, PD.1.index, IL12.index, costim.index, TCR.index),
bold = T, color = "white", background = "#D7261E") %>%
scroll_box(width = "800px", height = "500px")| term_id | term_name | p_value | term_size | query_size | intersection_size | precision | recall | source | intersection |
|---|---|---|---|---|---|---|---|---|---|
| GO:0006955 | immune response | 0.0000000 | 2294 | 712 | 196 | 0.2752809 | 0.0854403 | GO:BP | ENSG00000172057,ENSG00000100453,ENSG00000004468,ENSG00000164308,ENSG00000179344,ENSG00000119922,ENSG00000138496,ENSG00000204267,ENSG00000176083,ENSG00000211805,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000073861,ENSG00000156886,ENSG00000163599,ENSG00000132530,ENSG00000125347,ENSG00000100321,ENSG00000115523,ENSG00000211815,ENSG00000126709,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000162654,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000117560,ENSG00000203747,ENSG00000159216,ENSG00000151502,ENSG00000115415,ENSG00000119917,ENSG00000155629,ENSG00000069702,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000142089,ENSG00000160654,ENSG00000137265,ENSG00000117984,ENSG00000186470,ENSG00000150093,ENSG00000136167,ENSG00000211746,ENSG00000123609,ENSG00000096996,ENSG00000211698,ENSG00000138795,ENSG00000211745,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000211786,ENSG00000134539,ENSG00000117228,ENSG00000211721,ENSG00000111640,ENSG00000134352,ENSG00000139626,ENSG00000153563,ENSG00000117226,ENSG00000005844,ENSG00000211747,ENSG00000185201,ENSG00000116288,ENSG00000196230,ENSG00000134765,ENSG00000180644,ENSG00000073008,ENSG00000135114,ENSG00000134321,ENSG00000249437,ENSG00000137563,ENSG00000204264,ENSG00000077984,ENSG00000237254,ENSG00000167618,ENSG00000122223,ENSG00000136436,ENSG00000185885,ENSG00000172116,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000169230,ENSG00000213281,ENSG00000123131,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000204472,ENSG00000116030,ENSG00000165030,ENSG00000064666,ENSG00000072958,ENSG00000132274,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000152778,ENSG00000185745,ENSG00000163823,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000137959,ENSG00000100342,ENSG00000156234,ENSG00000021355,ENSG00000196954,ENSG00000101444,ENSG00000111331,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000145649,ENSG00000100299,ENSG00000013725,ENSG00000163131,ENSG00000125148,ENSG00000131504,ENSG00000198821,ENSG00000067560,ENSG00000213928,ENSG00000172794,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000211794,ENSG00000122122,ENSG00000165283,ENSG00000148175,ENSG00000204592,ENSG00000174371,ENSG00000137965,ENSG00000167286,ENSG00000187608,ENSG00000157873,ENSG00000162676,ENSG00000153310,ENSG00000070831,ENSG00000172936,ENSG00000179583,ENSG00000171302,ENSG00000147234,ENSG00000075624,ENSG00000096968,ENSG00000164164,ENSG00000128394,ENSG00000105612,ENSG00000168329,ENSG00000127666,ENSG00000139370,ENSG00000105697,ENSG00000223496,ENSG00000026751,ENSG00000116670,ENSG00000055163,ENSG00000123338,ENSG00000142867,ENSG00000110852,ENSG00000111335,ENSG00000198736,ENSG00000138646,ENSG00000140284,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000140319,ENSG00000111796,ENSG00000127951,ENSG00000101082,ENSG00000131019,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000148218,ENSG00000242574,ENSG00000147168,ENSG00000028137,ENSG00000132256,ENSG00000140575,ENSG00000175104 |
| GO:0002376 | immune system process | 0.0000000 | 3235 | 712 | 239 | 0.3356742 | 0.0738794 | GO:BP | ENSG00000172057,ENSG00000100453,ENSG00000004468,ENSG00000164308,ENSG00000179344,ENSG00000119922,ENSG00000138496,ENSG00000204267,ENSG00000113721,ENSG00000176083,ENSG00000211805,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000072110,ENSG00000073861,ENSG00000156886,ENSG00000163599,ENSG00000132530,ENSG00000125347,ENSG00000100321,ENSG00000179218,ENSG00000115523,ENSG00000211815,ENSG00000126709,ENSG00000159674,ENSG00000135077,ENSG00000092068,ENSG00000154451,ENSG00000162654,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000117560,ENSG00000203747,ENSG00000159216,ENSG00000151502,ENSG00000130164,ENSG00000115415,ENSG00000119917,ENSG00000155629,ENSG00000069702,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000142089,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000117984,ENSG00000186470,ENSG00000157216,ENSG00000150093,ENSG00000136167,ENSG00000211746,ENSG00000123609,ENSG00000138160,ENSG00000096996,ENSG00000172331,ENSG00000211698,ENSG00000138795,ENSG00000211745,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000211786,ENSG00000134539,ENSG00000117228,ENSG00000211721,ENSG00000111640,ENSG00000134352,ENSG00000139626,ENSG00000153563,ENSG00000117226,ENSG00000005844,ENSG00000211747,ENSG00000185201,ENSG00000116288,ENSG00000196230,ENSG00000134765,ENSG00000180644,ENSG00000073008,ENSG00000135114,ENSG00000134321,ENSG00000249437,ENSG00000137563,ENSG00000138642,ENSG00000204264,ENSG00000051341,ENSG00000077984,ENSG00000237254,ENSG00000011426,ENSG00000160219,ENSG00000167618,ENSG00000155846,ENSG00000122223,ENSG00000136436,ENSG00000185885,ENSG00000172116,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000242372,ENSG00000169230,ENSG00000153094,ENSG00000213281,ENSG00000123131,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000204472,ENSG00000163041,ENSG00000116030,ENSG00000165030,ENSG00000064666,ENSG00000072958,ENSG00000132274,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000152778,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000129422,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000110448,ENSG00000137959,ENSG00000100342,ENSG00000156234,ENSG00000021355,ENSG00000196954,ENSG00000101444,ENSG00000185650,ENSG00000111331,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000145649,ENSG00000071994,ENSG00000168421,ENSG00000100299,ENSG00000013725,ENSG00000163131,ENSG00000125148,ENSG00000131504,ENSG00000184916,ENSG00000198821,ENSG00000067560,ENSG00000197417,ENSG00000213928,ENSG00000114166,ENSG00000165304,ENSG00000172794,ENSG00000075340,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000211794,ENSG00000122122,ENSG00000172270,ENSG00000165283,ENSG00000148175,ENSG00000131747,ENSG00000141736,ENSG00000204592,ENSG00000132792,ENSG00000174371,ENSG00000137965,ENSG00000167286,ENSG00000187608,ENSG00000157873,ENSG00000162676,ENSG00000111863,ENSG00000042753,ENSG00000153310,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000179583,ENSG00000171302,ENSG00000147234,ENSG00000075624,ENSG00000096968,ENSG00000164164,ENSG00000128394,ENSG00000105612,ENSG00000168329,ENSG00000127666,ENSG00000139370,ENSG00000105697,ENSG00000223496,ENSG00000127022,ENSG00000026751,ENSG00000116670,ENSG00000055163,ENSG00000123338,ENSG00000142867,ENSG00000110852,ENSG00000111335,ENSG00000198736,ENSG00000138646,ENSG00000140284,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000091127,ENSG00000140319,ENSG00000111796,ENSG00000127951,ENSG00000101082,ENSG00000131019,ENSG00000197409,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000155090,ENSG00000148218,ENSG00000242574,ENSG00000147168,ENSG00000028137,ENSG00000132256,ENSG00000147889,ENSG00000140575,ENSG00000137193,ENSG00000175104,ENSG00000114631 |
| GO:0034341 | response to interferon-gamma | 0.0000000 | 200 | 712 | 44 | 0.0617978 | 0.2200000 | GO:BP | ENSG00000179344,ENSG00000138496,ENSG00000196126,ENSG00000125347,ENSG00000154451,ENSG00000162654,ENSG00000196735,ENSG00000117560,ENSG00000151502,ENSG00000115415,ENSG00000223865,ENSG00000231389,ENSG00000213512,ENSG00000142089,ENSG00000137265,ENSG00000123609,ENSG00000096996,ENSG00000111537,ENSG00000117228,ENSG00000111640,ENSG00000117226,ENSG00000185201,ENSG00000135114,ENSG00000136436,ENSG00000185885,ENSG00000089127,ENSG00000204472,ENSG00000116030,ENSG00000132274,ENSG00000166710,ENSG00000138071,ENSG00000111331,ENSG00000125148,ENSG00000213928,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000168961,ENSG00000204592,ENSG00000070831,ENSG00000179583,ENSG00000096968,ENSG00000111335,ENSG00000132256 |
| GO:0071345 | cellular response to cytokine stimulus | 0.0000000 | 1130 | 712 | 112 | 0.1573034 | 0.0991150 | GO:BP | ENSG00000179344,ENSG00000119922,ENSG00000138496,ENSG00000196126,ENSG00000092010,ENSG00000132530,ENSG00000125347,ENSG00000100321,ENSG00000126709,ENSG00000154451,ENSG00000162654,ENSG00000196735,ENSG00000019582,ENSG00000117560,ENSG00000072135,ENSG00000159216,ENSG00000151502,ENSG00000115415,ENSG00000119917,ENSG00000100911,ENSG00000113368,ENSG00000101057,ENSG00000177156,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000142089,ENSG00000167004,ENSG00000137265,ENSG00000127947,ENSG00000150093,ENSG00000136167,ENSG00000123609,ENSG00000096996,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000102554,ENSG00000232810,ENSG00000117228,ENSG00000204397,ENSG00000111640,ENSG00000134352,ENSG00000117226,ENSG00000185201,ENSG00000135114,ENSG00000134321,ENSG00000169855,ENSG00000204264,ENSG00000130402,ENSG00000185885,ENSG00000165949,ENSG00000123416,ENSG00000157601,ENSG00000089127,ENSG00000204472,ENSG00000089685,ENSG00000044574,ENSG00000116030,ENSG00000165030,ENSG00000064666,ENSG00000132274,ENSG00000166710,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000138071,ENSG00000166598,ENSG00000156234,ENSG00000196954,ENSG00000185650,ENSG00000111331,ENSG00000158869,ENSG00000100385,ENSG00000125148,ENSG00000067560,ENSG00000197417,ENSG00000213928,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000168961,ENSG00000204592,ENSG00000187608,ENSG00000157873,ENSG00000162676,ENSG00000070831,ENSG00000172936,ENSG00000179583,ENSG00000096968,ENSG00000164164,ENSG00000079999,ENSG00000168329,ENSG00000105697,ENSG00000127022,ENSG00000138617,ENSG00000111335,ENSG00000119318,ENSG00000041357,ENSG00000160255,ENSG00000197409,ENSG00000143321,ENSG00000148218,ENSG00000147168,ENSG00000135960,ENSG00000028137,ENSG00000132256,ENSG00000137193,ENSG00000175104,ENSG00000081985 |
| GO:0002252 | immune effector process | 0.0000000 | 1281 | 712 | 121 | 0.1699438 | 0.0944575 | GO:BP | ENSG00000172057,ENSG00000100453,ENSG00000179344,ENSG00000119922,ENSG00000138496,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000073861,ENSG00000125347,ENSG00000100321,ENSG00000126709,ENSG00000159674,ENSG00000135077,ENSG00000163840,ENSG00000089692,ENSG00000019582,ENSG00000203747,ENSG00000115415,ENSG00000119917,ENSG00000105639,ENSG00000142089,ENSG00000160654,ENSG00000196924,ENSG00000137265,ENSG00000117984,ENSG00000186470,ENSG00000136167,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000134539,ENSG00000117228,ENSG00000153563,ENSG00000117226,ENSG00000005844,ENSG00000185201,ENSG00000196230,ENSG00000134765,ENSG00000180644,ENSG00000073008,ENSG00000135114,ENSG00000134321,ENSG00000137563,ENSG00000122223,ENSG00000185885,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000213281,ENSG00000123131,ENSG00000157601,ENSG00000089127,ENSG00000064666,ENSG00000072958,ENSG00000132274,ENSG00000166710,ENSG00000111229,ENSG00000152778,ENSG00000185745,ENSG00000241258,ENSG00000138071,ENSG00000131236,ENSG00000137959,ENSG00000021355,ENSG00000111331,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000100299,ENSG00000163131,ENSG00000131504,ENSG00000198821,ENSG00000067560,ENSG00000213928,ENSG00000172794,ENSG00000185507,ENSG00000100298,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000122122,ENSG00000148175,ENSG00000204592,ENSG00000174371,ENSG00000187608,ENSG00000157873,ENSG00000153310,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000171302,ENSG00000147234,ENSG00000075624,ENSG00000128394,ENSG00000127666,ENSG00000139370,ENSG00000223496,ENSG00000026751,ENSG00000116670,ENSG00000055163,ENSG00000123338,ENSG00000142867,ENSG00000111335,ENSG00000138646,ENSG00000140284,ENSG00000254087,ENSG00000160255,ENSG00000140319,ENSG00000127951,ENSG00000101082,ENSG00000131019,ENSG00000196839,ENSG00000148218,ENSG00000242574,ENSG00000028137,ENSG00000132256,ENSG00000140575,ENSG00000175104 |
| GO:0034097 | response to cytokine | 0.0000000 | 1225 | 712 | 117 | 0.1643258 | 0.0955102 | GO:BP | ENSG00000004468,ENSG00000179344,ENSG00000119922,ENSG00000138496,ENSG00000196126,ENSG00000092010,ENSG00000132530,ENSG00000125347,ENSG00000100321,ENSG00000126709,ENSG00000154451,ENSG00000162654,ENSG00000196735,ENSG00000019582,ENSG00000117560,ENSG00000072135,ENSG00000159216,ENSG00000151502,ENSG00000115415,ENSG00000119917,ENSG00000100911,ENSG00000113368,ENSG00000101057,ENSG00000177156,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000142089,ENSG00000167004,ENSG00000137265,ENSG00000127947,ENSG00000150093,ENSG00000136167,ENSG00000123609,ENSG00000096996,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000102554,ENSG00000232810,ENSG00000117228,ENSG00000176890,ENSG00000204397,ENSG00000111640,ENSG00000134352,ENSG00000117226,ENSG00000185201,ENSG00000135114,ENSG00000134321,ENSG00000169855,ENSG00000204264,ENSG00000130402,ENSG00000136436,ENSG00000185885,ENSG00000165949,ENSG00000055332,ENSG00000123416,ENSG00000157601,ENSG00000089127,ENSG00000204472,ENSG00000089685,ENSG00000044574,ENSG00000116030,ENSG00000165030,ENSG00000064666,ENSG00000132274,ENSG00000166710,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000138071,ENSG00000166598,ENSG00000156234,ENSG00000196954,ENSG00000185650,ENSG00000111331,ENSG00000158869,ENSG00000100385,ENSG00000125148,ENSG00000067560,ENSG00000197417,ENSG00000213928,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000204592,ENSG00000187608,ENSG00000157873,ENSG00000162676,ENSG00000070831,ENSG00000172936,ENSG00000179583,ENSG00000096968,ENSG00000164164,ENSG00000079999,ENSG00000168329,ENSG00000105697,ENSG00000127022,ENSG00000138617,ENSG00000111335,ENSG00000119318,ENSG00000041357,ENSG00000160255,ENSG00000197409,ENSG00000143321,ENSG00000148218,ENSG00000147168,ENSG00000135960,ENSG00000028137,ENSG00000132256,ENSG00000137193,ENSG00000175104,ENSG00000081985 |
| GO:0071346 | cellular response to interferon-gamma | 0.0000000 | 180 | 712 | 40 | 0.0561798 | 0.2222222 | GO:BP | ENSG00000179344,ENSG00000138496,ENSG00000196126,ENSG00000125347,ENSG00000154451,ENSG00000162654,ENSG00000196735,ENSG00000117560,ENSG00000151502,ENSG00000115415,ENSG00000223865,ENSG00000231389,ENSG00000213512,ENSG00000137265,ENSG00000123609,ENSG00000096996,ENSG00000111537,ENSG00000117228,ENSG00000111640,ENSG00000117226,ENSG00000135114,ENSG00000089127,ENSG00000204472,ENSG00000116030,ENSG00000132274,ENSG00000166710,ENSG00000138071,ENSG00000111331,ENSG00000125148,ENSG00000213928,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000168961,ENSG00000204592,ENSG00000070831,ENSG00000179583,ENSG00000096968,ENSG00000111335,ENSG00000132256 |
| GO:0045087 | innate immune response | 0.0000000 | 1010 | 712 | 103 | 0.1446629 | 0.1019802 | GO:BP | ENSG00000100453,ENSG00000179344,ENSG00000119922,ENSG00000138496,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000132530,ENSG00000125347,ENSG00000126709,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000162654,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000117560,ENSG00000151502,ENSG00000115415,ENSG00000119917,ENSG00000155629,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000142089,ENSG00000137265,ENSG00000123609,ENSG00000096996,ENSG00000211698,ENSG00000111537,ENSG00000189430,ENSG00000134539,ENSG00000117228,ENSG00000111640,ENSG00000117226,ENSG00000185201,ENSG00000196230,ENSG00000073008,ENSG00000135114,ENSG00000134321,ENSG00000249437,ENSG00000204264,ENSG00000122223,ENSG00000136436,ENSG00000185885,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000213281,ENSG00000157601,ENSG00000089127,ENSG00000204472,ENSG00000116030,ENSG00000132274,ENSG00000166710,ENSG00000152778,ENSG00000185745,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000100342,ENSG00000196954,ENSG00000111331,ENSG00000158869,ENSG00000013725,ENSG00000163131,ENSG00000125148,ENSG00000213928,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000204592,ENSG00000187608,ENSG00000157873,ENSG00000162676,ENSG00000070831,ENSG00000172936,ENSG00000179583,ENSG00000096968,ENSG00000164164,ENSG00000128394,ENSG00000168329,ENSG00000127666,ENSG00000026751,ENSG00000142867,ENSG00000111335,ENSG00000198736,ENSG00000138646,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000131019,ENSG00000137312,ENSG00000132256,ENSG00000175104 |
| GO:0098542 | defense response to other organism | 0.0000000 | 1212 | 712 | 114 | 0.1601124 | 0.0940594 | GO:BP | ENSG00000100453,ENSG00000179344,ENSG00000119922,ENSG00000138496,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000073605,ENSG00000132530,ENSG00000125347,ENSG00000115523,ENSG00000126709,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000162654,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000117560,ENSG00000151502,ENSG00000115415,ENSG00000119917,ENSG00000155629,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000142089,ENSG00000196924,ENSG00000137265,ENSG00000123609,ENSG00000096996,ENSG00000211698,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000134539,ENSG00000117228,ENSG00000111640,ENSG00000167914,ENSG00000117226,ENSG00000185201,ENSG00000196230,ENSG00000180644,ENSG00000073008,ENSG00000135114,ENSG00000134321,ENSG00000249437,ENSG00000204264,ENSG00000122223,ENSG00000136436,ENSG00000185885,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000213281,ENSG00000157601,ENSG00000089127,ENSG00000204472,ENSG00000116030,ENSG00000132274,ENSG00000166710,ENSG00000152778,ENSG00000185745,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000137959,ENSG00000100342,ENSG00000156234,ENSG00000196954,ENSG00000111331,ENSG00000158869,ENSG00000013725,ENSG00000163131,ENSG00000125148,ENSG00000213928,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000204592,ENSG00000187608,ENSG00000157873,ENSG00000162676,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000179583,ENSG00000096968,ENSG00000164164,ENSG00000128394,ENSG00000168329,ENSG00000127666,ENSG00000105697,ENSG00000026751,ENSG00000142867,ENSG00000111335,ENSG00000198736,ENSG00000138646,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000127951,ENSG00000131019,ENSG00000137312,ENSG00000132256,ENSG00000175104 |
| GO:0006950 | response to stress | 0.0000000 | 4147 | 712 | 264 | 0.3707865 | 0.0636605 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000179344,ENSG00000156587,ENSG00000119922,ENSG00000138496,ENSG00000113721,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000073605,ENSG00000163599,ENSG00000132530,ENSG00000125347,ENSG00000108679,ENSG00000109956,ENSG00000179218,ENSG00000115523,ENSG00000126709,ENSG00000159674,ENSG00000135077,ENSG00000165891,ENSG00000154451,ENSG00000162654,ENSG00000100427,ENSG00000134184,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000151502,ENSG00000130164,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000155629,ENSG00000186469,ENSG00000069702,ENSG00000100911,ENSG00000164111,ENSG00000163029,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000142089,ENSG00000169252,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000112029,ENSG00000127947,ENSG00000150093,ENSG00000123609,ENSG00000173848,ENSG00000096996,ENSG00000165617,ENSG00000125249,ENSG00000211698,ENSG00000111206,ENSG00000111537,ENSG00000102554,ENSG00000189430,ENSG00000232810,ENSG00000183691,ENSG00000134539,ENSG00000117228,ENSG00000204397,ENSG00000108179,ENSG00000111640,ENSG00000183734,ENSG00000172292,ENSG00000134352,ENSG00000167914,ENSG00000132646,ENSG00000128335,ENSG00000117226,ENSG00000128284,ENSG00000005844,ENSG00000130592,ENSG00000103148,ENSG00000185201,ENSG00000116288,ENSG00000196230,ENSG00000180644,ENSG00000111602,ENSG00000073008,ENSG00000135114,ENSG00000134321,ENSG00000249437,ENSG00000175793,ENSG00000023572,ENSG00000100918,ENSG00000156463,ENSG00000204264,ENSG00000051341,ENSG00000188191,ENSG00000077984,ENSG00000130402,ENSG00000170312,ENSG00000105887,ENSG00000155846,ENSG00000122223,ENSG00000136436,ENSG00000185885,ENSG00000164830,ENSG00000117394,ENSG00000131944,ENSG00000165949,ENSG00000092853,ENSG00000055332,ENSG00000239713,ENSG00000153094,ENSG00000213445,ENSG00000104687,ENSG00000213281,ENSG00000123131,ENSG00000159200,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000167723,ENSG00000152256,ENSG00000204472,ENSG00000163041,ENSG00000044574,ENSG00000133315,ENSG00000116030,ENSG00000064666,ENSG00000132274,ENSG00000166710,ENSG00000073803,ENSG00000163545,ENSG00000152778,ENSG00000185745,ENSG00000163823,ENSG00000166454,ENSG00000180667,ENSG00000166197,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000137959,ENSG00000100342,ENSG00000156234,ENSG00000129675,ENSG00000196954,ENSG00000093009,ENSG00000101444,ENSG00000185650,ENSG00000100605,ENSG00000125871,ENSG00000111331,ENSG00000074800,ENSG00000143476,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000053254,ENSG00000013725,ENSG00000158006,ENSG00000163131,ENSG00000170881,ENSG00000125148,ENSG00000139921,ENSG00000011485,ENSG00000067560,ENSG00000197417,ENSG00000213928,ENSG00000213719,ENSG00000165304,ENSG00000134202,ENSG00000133026,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000165283,ENSG00000131747,ENSG00000141736,ENSG00000204592,ENSG00000132182,ENSG00000083444,ENSG00000174371,ENSG00000187608,ENSG00000157873,ENSG00000139579,ENSG00000162676,ENSG00000111863,ENSG00000106462,ENSG00000104765,ENSG00000070831,ENSG00000079691,ENSG00000172936,ENSG00000179583,ENSG00000178719,ENSG00000141030,ENSG00000197043,ENSG00000054965,ENSG00000075624,ENSG00000096968,ENSG00000164164,ENSG00000128394,ENSG00000075239,ENSG00000176641,ENSG00000109674,ENSG00000079999,ENSG00000168329,ENSG00000127666,ENSG00000105697,ENSG00000127022,ENSG00000026751,ENSG00000138617,ENSG00000125648,ENSG00000116670,ENSG00000090520,ENSG00000132386,ENSG00000128272,ENSG00000142867,ENSG00000111335,ENSG00000114126,ENSG00000126432,ENSG00000198736,ENSG00000138646,ENSG00000049541,ENSG00000104738,ENSG00000119318,ENSG00000172531,ENSG00000137309,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000213366,ENSG00000177076,ENSG00000127951,ENSG00000155660,ENSG00000131019,ENSG00000197409,ENSG00000172667,ENSG00000137312,ENSG00000196839,ENSG00000143321,ENSG00000136104,ENSG00000155090,ENSG00000148218,ENSG00000177674,ENSG00000135960,ENSG00000028137,ENSG00000178685,ENSG00000132256,ENSG00000147889,ENSG00000111450,ENSG00000175104,ENSG00000078124,ENSG00000110218,ENSG00000169554,ENSG00000170485,ENSG00000112759 |
| GO:0060333 | interferon-gamma-mediated signaling pathway | 0.0000000 | 87 | 712 | 27 | 0.0379213 | 0.3103448 | GO:BP | ENSG00000138496,ENSG00000196126,ENSG00000125347,ENSG00000196735,ENSG00000115415,ENSG00000223865,ENSG00000231389,ENSG00000137265,ENSG00000123609,ENSG00000111537,ENSG00000117228,ENSG00000135114,ENSG00000089127,ENSG00000116030,ENSG00000132274,ENSG00000166710,ENSG00000111331,ENSG00000125148,ENSG00000213928,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000204592,ENSG00000179583,ENSG00000096968,ENSG00000111335,ENSG00000132256 |
| GO:0009607 | response to biotic stimulus | 0.0000000 | 1583 | 712 | 133 | 0.1867978 | 0.0840177 | GO:BP | ENSG00000100453,ENSG00000179344,ENSG00000119922,ENSG00000138496,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000073605,ENSG00000073861,ENSG00000132530,ENSG00000125347,ENSG00000115523,ENSG00000126709,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000162654,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000117560,ENSG00000151502,ENSG00000115415,ENSG00000119917,ENSG00000155629,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000117632,ENSG00000142089,ENSG00000196924,ENSG00000137265,ENSG00000123609,ENSG00000096996,ENSG00000211698,ENSG00000172757,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000134539,ENSG00000117228,ENSG00000204397,ENSG00000111640,ENSG00000167914,ENSG00000100380,ENSG00000117226,ENSG00000185201,ENSG00000196230,ENSG00000180644,ENSG00000073008,ENSG00000135114,ENSG00000134321,ENSG00000249437,ENSG00000138642,ENSG00000204264,ENSG00000122223,ENSG00000136436,ENSG00000185885,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000153094,ENSG00000213281,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000204472,ENSG00000044574,ENSG00000116030,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000152778,ENSG00000185745,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000137959,ENSG00000100342,ENSG00000156234,ENSG00000196954,ENSG00000111331,ENSG00000074800,ENSG00000158869,ENSG00000145649,ENSG00000013725,ENSG00000163131,ENSG00000125148,ENSG00000067560,ENSG00000197417,ENSG00000213928,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000204592,ENSG00000137965,ENSG00000187608,ENSG00000157873,ENSG00000162676,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000179583,ENSG00000096968,ENSG00000164164,ENSG00000128394,ENSG00000168329,ENSG00000127666,ENSG00000105697,ENSG00000026751,ENSG00000142867,ENSG00000111335,ENSG00000198736,ENSG00000138646,ENSG00000137309,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000127951,ENSG00000131019,ENSG00000137312,ENSG00000148218,ENSG00000028137,ENSG00000132256,ENSG00000175104,ENSG00000081985 |
| GO:0051707 | response to other organism | 0.0000000 | 1551 | 712 | 131 | 0.1839888 | 0.0844616 | GO:BP | ENSG00000100453,ENSG00000179344,ENSG00000119922,ENSG00000138496,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000073605,ENSG00000073861,ENSG00000132530,ENSG00000125347,ENSG00000115523,ENSG00000126709,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000162654,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000117560,ENSG00000151502,ENSG00000115415,ENSG00000119917,ENSG00000155629,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000117632,ENSG00000142089,ENSG00000196924,ENSG00000137265,ENSG00000123609,ENSG00000096996,ENSG00000211698,ENSG00000172757,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000134539,ENSG00000117228,ENSG00000204397,ENSG00000111640,ENSG00000167914,ENSG00000100380,ENSG00000117226,ENSG00000185201,ENSG00000196230,ENSG00000180644,ENSG00000073008,ENSG00000135114,ENSG00000134321,ENSG00000249437,ENSG00000138642,ENSG00000204264,ENSG00000122223,ENSG00000136436,ENSG00000185885,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000213281,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000204472,ENSG00000116030,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000152778,ENSG00000185745,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000137959,ENSG00000100342,ENSG00000156234,ENSG00000196954,ENSG00000111331,ENSG00000074800,ENSG00000158869,ENSG00000145649,ENSG00000013725,ENSG00000163131,ENSG00000125148,ENSG00000067560,ENSG00000197417,ENSG00000213928,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000204592,ENSG00000137965,ENSG00000187608,ENSG00000157873,ENSG00000162676,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000179583,ENSG00000096968,ENSG00000164164,ENSG00000128394,ENSG00000168329,ENSG00000127666,ENSG00000105697,ENSG00000026751,ENSG00000142867,ENSG00000111335,ENSG00000198736,ENSG00000138646,ENSG00000137309,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000127951,ENSG00000131019,ENSG00000137312,ENSG00000148218,ENSG00000028137,ENSG00000132256,ENSG00000175104,ENSG00000081985 |
| GO:0043207 | response to external biotic stimulus | 0.0000000 | 1553 | 712 | 131 | 0.1839888 | 0.0843529 | GO:BP | ENSG00000100453,ENSG00000179344,ENSG00000119922,ENSG00000138496,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000073605,ENSG00000073861,ENSG00000132530,ENSG00000125347,ENSG00000115523,ENSG00000126709,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000162654,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000117560,ENSG00000151502,ENSG00000115415,ENSG00000119917,ENSG00000155629,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000117632,ENSG00000142089,ENSG00000196924,ENSG00000137265,ENSG00000123609,ENSG00000096996,ENSG00000211698,ENSG00000172757,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000134539,ENSG00000117228,ENSG00000204397,ENSG00000111640,ENSG00000167914,ENSG00000100380,ENSG00000117226,ENSG00000185201,ENSG00000196230,ENSG00000180644,ENSG00000073008,ENSG00000135114,ENSG00000134321,ENSG00000249437,ENSG00000138642,ENSG00000204264,ENSG00000122223,ENSG00000136436,ENSG00000185885,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000213281,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000204472,ENSG00000116030,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000152778,ENSG00000185745,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000137959,ENSG00000100342,ENSG00000156234,ENSG00000196954,ENSG00000111331,ENSG00000074800,ENSG00000158869,ENSG00000145649,ENSG00000013725,ENSG00000163131,ENSG00000125148,ENSG00000067560,ENSG00000197417,ENSG00000213928,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000204592,ENSG00000137965,ENSG00000187608,ENSG00000157873,ENSG00000162676,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000179583,ENSG00000096968,ENSG00000164164,ENSG00000128394,ENSG00000168329,ENSG00000127666,ENSG00000105697,ENSG00000026751,ENSG00000142867,ENSG00000111335,ENSG00000198736,ENSG00000138646,ENSG00000137309,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000127951,ENSG00000131019,ENSG00000137312,ENSG00000148218,ENSG00000028137,ENSG00000132256,ENSG00000175104,ENSG00000081985 |
| GO:0009615 | response to virus | 0.0000000 | 337 | 712 | 51 | 0.0716292 | 0.1513353 | GO:BP | ENSG00000119922,ENSG00000138496,ENSG00000073861,ENSG00000125347,ENSG00000126709,ENSG00000159674,ENSG00000163840,ENSG00000115415,ENSG00000119917,ENSG00000117632,ENSG00000142089,ENSG00000196924,ENSG00000096996,ENSG00000172757,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000117226,ENSG00000185201,ENSG00000180644,ENSG00000135114,ENSG00000134321,ENSG00000185885,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000157601,ENSG00000089127,ENSG00000132274,ENSG00000152778,ENSG00000185745,ENSG00000241258,ENSG00000137959,ENSG00000111331,ENSG00000074800,ENSG00000213928,ENSG00000185507,ENSG00000100298,ENSG00000115267,ENSG00000168961,ENSG00000137965,ENSG00000187608,ENSG00000104765,ENSG00000172936,ENSG00000128394,ENSG00000127666,ENSG00000111335,ENSG00000138646,ENSG00000137309,ENSG00000127951,ENSG00000132256 |
| GO:0019221 | cytokine-mediated signaling pathway | 0.0000000 | 799 | 712 | 83 | 0.1165730 | 0.1038798 | GO:BP | ENSG00000119922,ENSG00000138496,ENSG00000196126,ENSG00000092010,ENSG00000132530,ENSG00000125347,ENSG00000126709,ENSG00000196735,ENSG00000019582,ENSG00000117560,ENSG00000159216,ENSG00000115415,ENSG00000119917,ENSG00000100911,ENSG00000113368,ENSG00000177156,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000105639,ENSG00000142089,ENSG00000137265,ENSG00000150093,ENSG00000136167,ENSG00000123609,ENSG00000096996,ENSG00000172757,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000204397,ENSG00000134352,ENSG00000185201,ENSG00000135114,ENSG00000134321,ENSG00000169855,ENSG00000204264,ENSG00000130402,ENSG00000185885,ENSG00000165949,ENSG00000157601,ENSG00000089127,ENSG00000089685,ENSG00000116030,ENSG00000064666,ENSG00000132274,ENSG00000166710,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000166598,ENSG00000156234,ENSG00000196954,ENSG00000111331,ENSG00000158869,ENSG00000100385,ENSG00000125148,ENSG00000213928,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000204592,ENSG00000187608,ENSG00000157873,ENSG00000162676,ENSG00000070831,ENSG00000172936,ENSG00000179583,ENSG00000096968,ENSG00000164164,ENSG00000168329,ENSG00000127022,ENSG00000111335,ENSG00000041357,ENSG00000160255,ENSG00000197409,ENSG00000147168,ENSG00000135960,ENSG00000028137,ENSG00000132256,ENSG00000137193,ENSG00000175104,ENSG00000081985 |
| GO:0002682 | regulation of immune system process | 0.0000000 | 1688 | 712 | 135 | 0.1896067 | 0.0799763 | GO:BP | ENSG00000004468,ENSG00000179344,ENSG00000138496,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000179218,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000019582,ENSG00000203747,ENSG00000159216,ENSG00000130164,ENSG00000115415,ENSG00000155629,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000105639,ENSG00000160654,ENSG00000137265,ENSG00000186470,ENSG00000150093,ENSG00000123609,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000134539,ENSG00000117228,ENSG00000134352,ENSG00000139626,ENSG00000153563,ENSG00000005844,ENSG00000116288,ENSG00000073008,ENSG00000134321,ENSG00000204264,ENSG00000077984,ENSG00000167618,ENSG00000155846,ENSG00000122223,ENSG00000185885,ENSG00000172116,ENSG00000055332,ENSG00000239713,ENSG00000242372,ENSG00000169230,ENSG00000213281,ENSG00000148400,ENSG00000204472,ENSG00000163041,ENSG00000116030,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000129422,ENSG00000138071,ENSG00000166598,ENSG00000110448,ENSG00000156234,ENSG00000185650,ENSG00000105220,ENSG00000158869,ENSG00000071994,ENSG00000168421,ENSG00000013725,ENSG00000163131,ENSG00000198821,ENSG00000067560,ENSG00000197417,ENSG00000114166,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000122122,ENSG00000165283,ENSG00000141736,ENSG00000204592,ENSG00000167286,ENSG00000187608,ENSG00000157873,ENSG00000162676,ENSG00000111863,ENSG00000153310,ENSG00000070831,ENSG00000172936,ENSG00000075624,ENSG00000096968,ENSG00000164164,ENSG00000128394,ENSG00000105612,ENSG00000168329,ENSG00000127666,ENSG00000223496,ENSG00000026751,ENSG00000116670,ENSG00000055163,ENSG00000123338,ENSG00000142867,ENSG00000110852,ENSG00000138646,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000091127,ENSG00000111796,ENSG00000127951,ENSG00000101082,ENSG00000131019,ENSG00000197409,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000155090,ENSG00000242574,ENSG00000028137,ENSG00000132256,ENSG00000147889,ENSG00000137193,ENSG00000175104 |
| GO:0051607 | defense response to virus | 0.0000000 | 251 | 712 | 42 | 0.0589888 | 0.1673307 | GO:BP | ENSG00000119922,ENSG00000138496,ENSG00000125347,ENSG00000126709,ENSG00000159674,ENSG00000163840,ENSG00000115415,ENSG00000119917,ENSG00000142089,ENSG00000196924,ENSG00000096996,ENSG00000111537,ENSG00000117228,ENSG00000117226,ENSG00000185201,ENSG00000180644,ENSG00000135114,ENSG00000134321,ENSG00000185885,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000157601,ENSG00000089127,ENSG00000132274,ENSG00000152778,ENSG00000185745,ENSG00000241258,ENSG00000137959,ENSG00000111331,ENSG00000213928,ENSG00000185507,ENSG00000100298,ENSG00000115267,ENSG00000187608,ENSG00000104765,ENSG00000128394,ENSG00000127666,ENSG00000111335,ENSG00000138646,ENSG00000127951,ENSG00000132256 |
| GO:0006952 | defense response | 0.0000000 | 1783 | 712 | 137 | 0.1924157 | 0.0768368 | GO:BP | ENSG00000100453,ENSG00000179344,ENSG00000119922,ENSG00000138496,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000073605,ENSG00000132530,ENSG00000125347,ENSG00000108679,ENSG00000115523,ENSG00000126709,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000162654,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000151502,ENSG00000130164,ENSG00000115415,ENSG00000119917,ENSG00000155629,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000142089,ENSG00000196924,ENSG00000137265,ENSG00000150093,ENSG00000123609,ENSG00000096996,ENSG00000211698,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000134539,ENSG00000117228,ENSG00000111640,ENSG00000172292,ENSG00000134352,ENSG00000167914,ENSG00000128335,ENSG00000117226,ENSG00000128284,ENSG00000005844,ENSG00000130592,ENSG00000185201,ENSG00000116288,ENSG00000196230,ENSG00000180644,ENSG00000073008,ENSG00000135114,ENSG00000134321,ENSG00000249437,ENSG00000204264,ENSG00000077984,ENSG00000122223,ENSG00000136436,ENSG00000185885,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000213281,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000204472,ENSG00000116030,ENSG00000132274,ENSG00000166710,ENSG00000152778,ENSG00000185745,ENSG00000163823,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000137959,ENSG00000100342,ENSG00000156234,ENSG00000196954,ENSG00000101444,ENSG00000111331,ENSG00000158869,ENSG00000013725,ENSG00000163131,ENSG00000125148,ENSG00000197417,ENSG00000213928,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000204592,ENSG00000187608,ENSG00000157873,ENSG00000162676,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000179583,ENSG00000096968,ENSG00000164164,ENSG00000128394,ENSG00000168329,ENSG00000127666,ENSG00000105697,ENSG00000026751,ENSG00000132386,ENSG00000142867,ENSG00000111335,ENSG00000126432,ENSG00000198736,ENSG00000138646,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000127951,ENSG00000131019,ENSG00000137312,ENSG00000196839,ENSG00000028137,ENSG00000132256,ENSG00000175104,ENSG00000078124,ENSG00000170485 |
| GO:0060337 | type I interferon signaling pathway | 0.0000000 | 95 | 712 | 25 | 0.0351124 | 0.2631579 | GO:BP | ENSG00000119922,ENSG00000132530,ENSG00000125347,ENSG00000126709,ENSG00000115415,ENSG00000119917,ENSG00000142089,ENSG00000137265,ENSG00000185201,ENSG00000135114,ENSG00000134321,ENSG00000204264,ENSG00000185885,ENSG00000165949,ENSG00000157601,ENSG00000089127,ENSG00000185745,ENSG00000111331,ENSG00000213928,ENSG00000185507,ENSG00000204642,ENSG00000204592,ENSG00000187608,ENSG00000172936,ENSG00000111335 |
| GO:0071357 | cellular response to type I interferon | 0.0000000 | 95 | 712 | 25 | 0.0351124 | 0.2631579 | GO:BP | ENSG00000119922,ENSG00000132530,ENSG00000125347,ENSG00000126709,ENSG00000115415,ENSG00000119917,ENSG00000142089,ENSG00000137265,ENSG00000185201,ENSG00000135114,ENSG00000134321,ENSG00000204264,ENSG00000185885,ENSG00000165949,ENSG00000157601,ENSG00000089127,ENSG00000185745,ENSG00000111331,ENSG00000213928,ENSG00000185507,ENSG00000204642,ENSG00000204592,ENSG00000187608,ENSG00000172936,ENSG00000111335 |
| GO:0034340 | response to type I interferon | 0.0000000 | 99 | 712 | 25 | 0.0351124 | 0.2525253 | GO:BP | ENSG00000119922,ENSG00000132530,ENSG00000125347,ENSG00000126709,ENSG00000115415,ENSG00000119917,ENSG00000142089,ENSG00000137265,ENSG00000185201,ENSG00000135114,ENSG00000134321,ENSG00000204264,ENSG00000185885,ENSG00000165949,ENSG00000157601,ENSG00000089127,ENSG00000185745,ENSG00000111331,ENSG00000213928,ENSG00000185507,ENSG00000204642,ENSG00000204592,ENSG00000187608,ENSG00000172936,ENSG00000111335 |
| GO:0043900 | regulation of multi-organism process | 0.0000000 | 774 | 712 | 77 | 0.1081461 | 0.0994832 | GO:BP | ENSG00000138496,ENSG00000117281,ENSG00000092010,ENSG00000125347,ENSG00000179218,ENSG00000135077,ENSG00000154451,ENSG00000163840,ENSG00000089692,ENSG00000019582,ENSG00000115415,ENSG00000155629,ENSG00000100911,ENSG00000170315,ENSG00000142089,ENSG00000137265,ENSG00000123609,ENSG00000096996,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000204397,ENSG00000111640,ENSG00000185201,ENSG00000180644,ENSG00000073008,ENSG00000135114,ENSG00000134321,ENSG00000204264,ENSG00000185885,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000153094,ENSG00000213281,ENSG00000123131,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000116030,ENSG00000152778,ENSG00000185745,ENSG00000166598,ENSG00000111348,ENSG00000111331,ENSG00000158869,ENSG00000163131,ENSG00000185507,ENSG00000100298,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000148175,ENSG00000131747,ENSG00000204592,ENSG00000187608,ENSG00000162676,ENSG00000172936,ENSG00000096968,ENSG00000164164,ENSG00000128394,ENSG00000127666,ENSG00000142867,ENSG00000111335,ENSG00000138646,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000127951,ENSG00000137312,ENSG00000196839,ENSG00000178685,ENSG00000132256,ENSG00000175104,ENSG00000166794 |
| GO:0007159 | leukocyte cell-cell adhesion | 0.0000000 | 356 | 712 | 48 | 0.0674157 | 0.1348315 | GO:BP | ENSG00000179344,ENSG00000117281,ENSG00000196126,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000150093,ENSG00000096996,ENSG00000111537,ENSG00000232810,ENSG00000134352,ENSG00000139626,ENSG00000005844,ENSG00000167123,ENSG00000204472,ENSG00000147065,ENSG00000110448,ENSG00000168421,ENSG00000013725,ENSG00000067560,ENSG00000075340,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000111863,ENSG00000153310,ENSG00000070831,ENSG00000168329,ENSG00000123338,ENSG00000142867,ENSG00000254087,ENSG00000160255,ENSG00000127951,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000147889,ENSG00000175104,ENSG00000114631 |
| GO:0050776 | regulation of immune response | 0.0000000 | 1116 | 712 | 97 | 0.1362360 | 0.0869176 | GO:BP | ENSG00000004468,ENSG00000179344,ENSG00000138496,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000089692,ENSG00000196735,ENSG00000019582,ENSG00000203747,ENSG00000159216,ENSG00000115415,ENSG00000155629,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000105639,ENSG00000160654,ENSG00000137265,ENSG00000186470,ENSG00000150093,ENSG00000123609,ENSG00000096996,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000134539,ENSG00000117228,ENSG00000134352,ENSG00000139626,ENSG00000153563,ENSG00000005844,ENSG00000116288,ENSG00000073008,ENSG00000134321,ENSG00000204264,ENSG00000167618,ENSG00000185885,ENSG00000172116,ENSG00000213281,ENSG00000116030,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000138071,ENSG00000166598,ENSG00000156234,ENSG00000158869,ENSG00000163131,ENSG00000198821,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000122122,ENSG00000165283,ENSG00000204592,ENSG00000167286,ENSG00000157873,ENSG00000162676,ENSG00000153310,ENSG00000070831,ENSG00000172936,ENSG00000075624,ENSG00000096968,ENSG00000164164,ENSG00000105612,ENSG00000127666,ENSG00000223496,ENSG00000026751,ENSG00000116670,ENSG00000055163,ENSG00000123338,ENSG00000142867,ENSG00000110852,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000111796,ENSG00000127951,ENSG00000101082,ENSG00000131019,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000028137,ENSG00000132256,ENSG00000175104 |
| GO:0042110 | T cell activation | 0.0000000 | 478 | 712 | 56 | 0.0786517 | 0.1171548 | GO:BP | ENSG00000179344,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000160654,ENSG00000137265,ENSG00000136167,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000134352,ENSG00000153563,ENSG00000005844,ENSG00000134321,ENSG00000172116,ENSG00000169230,ENSG00000204472,ENSG00000166710,ENSG00000147065,ENSG00000110448,ENSG00000185650,ENSG00000158869,ENSG00000168421,ENSG00000013725,ENSG00000184916,ENSG00000067560,ENSG00000168961,ENSG00000122122,ENSG00000165283,ENSG00000141736,ENSG00000204592,ENSG00000167286,ENSG00000157873,ENSG00000153310,ENSG00000070831,ENSG00000123338,ENSG00000142867,ENSG00000254087,ENSG00000127951,ENSG00000101082,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000028137,ENSG00000147889,ENSG00000175104 |
| GO:0002250 | adaptive immune response | 0.0000000 | 677 | 712 | 69 | 0.0969101 | 0.1019202 | GO:BP | ENSG00000164308,ENSG00000179344,ENSG00000204267,ENSG00000176083,ENSG00000211805,ENSG00000117281,ENSG00000196126,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000211815,ENSG00000135077,ENSG00000089692,ENSG00000196735,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000160654,ENSG00000137265,ENSG00000186470,ENSG00000211746,ENSG00000096996,ENSG00000211698,ENSG00000138795,ENSG00000211745,ENSG00000111537,ENSG00000232810,ENSG00000211786,ENSG00000211721,ENSG00000134352,ENSG00000153563,ENSG00000211747,ENSG00000180644,ENSG00000073008,ENSG00000134321,ENSG00000237254,ENSG00000122223,ENSG00000172116,ENSG00000166710,ENSG00000211810,ENSG00000156234,ENSG00000158869,ENSG00000013725,ENSG00000163131,ENSG00000198821,ENSG00000185507,ENSG00000204642,ENSG00000211794,ENSG00000122122,ENSG00000204592,ENSG00000174371,ENSG00000167286,ENSG00000157873,ENSG00000153310,ENSG00000172936,ENSG00000096968,ENSG00000223496,ENSG00000026751,ENSG00000116670,ENSG00000142867,ENSG00000254087,ENSG00000127951,ENSG00000101082,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000028137,ENSG00000175104 |
| GO:0016032 | viral process | 0.0000000 | 838 | 712 | 78 | 0.1095506 | 0.0930788 | GO:BP | ENSG00000204267,ENSG00000196126,ENSG00000019582,ENSG00000130164,ENSG00000115415,ENSG00000170315,ENSG00000142089,ENSG00000150093,ENSG00000172757,ENSG00000138795,ENSG00000232810,ENSG00000176890,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000185201,ENSG00000073008,ENSG00000135114,ENSG00000134321,ENSG00000152465,ENSG00000204264,ENSG00000170312,ENSG00000136436,ENSG00000185885,ENSG00000172116,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000153094,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000116030,ENSG00000072958,ENSG00000132274,ENSG00000166710,ENSG00000152778,ENSG00000185745,ENSG00000147065,ENSG00000111331,ENSG00000136717,ENSG00000100385,ENSG00000198821,ENSG00000067560,ENSG00000114166,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000115267,ENSG00000204256,ENSG00000087302,ENSG00000168961,ENSG00000148175,ENSG00000131747,ENSG00000132182,ENSG00000187608,ENSG00000157873,ENSG00000162676,ENSG00000042753,ENSG00000104765,ENSG00000070831,ENSG00000128394,ENSG00000079999,ENSG00000168329,ENSG00000127666,ENSG00000111335,ENSG00000172531,ENSG00000137309,ENSG00000041357,ENSG00000125354,ENSG00000254087,ENSG00000131019,ENSG00000147168,ENSG00000178685,ENSG00000132256,ENSG00000140575,ENSG00000166794 |
| GO:0009605 | response to external stimulus | 0.0000000 | 2923 | 712 | 188 | 0.2640449 | 0.0643175 | GO:BP | ENSG00000100453,ENSG00000179344,ENSG00000119922,ENSG00000138496,ENSG00000113721,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000073605,ENSG00000073861,ENSG00000132530,ENSG00000125347,ENSG00000179218,ENSG00000115523,ENSG00000126709,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000162654,ENSG00000155657,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000151502,ENSG00000173482,ENSG00000130164,ENSG00000115415,ENSG00000119917,ENSG00000155629,ENSG00000091129,ENSG00000100911,ENSG00000221866,ENSG00000164111,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000117632,ENSG00000142089,ENSG00000169252,ENSG00000196924,ENSG00000137265,ENSG00000123609,ENSG00000096996,ENSG00000211698,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000183691,ENSG00000134539,ENSG00000117228,ENSG00000176890,ENSG00000204397,ENSG00000111640,ENSG00000134352,ENSG00000167914,ENSG00000132646,ENSG00000100380,ENSG00000117226,ENSG00000103148,ENSG00000185201,ENSG00000116288,ENSG00000196230,ENSG00000180644,ENSG00000073008,ENSG00000135114,ENSG00000134321,ENSG00000249437,ENSG00000169855,ENSG00000023572,ENSG00000152465,ENSG00000138642,ENSG00000204264,ENSG00000077984,ENSG00000105887,ENSG00000122223,ENSG00000136436,ENSG00000185885,ENSG00000117394,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000213445,ENSG00000213281,ENSG00000159200,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000204472,ENSG00000044574,ENSG00000116030,ENSG00000118263,ENSG00000064666,ENSG00000072958,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000163545,ENSG00000152778,ENSG00000185745,ENSG00000163823,ENSG00000129422,ENSG00000126016,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000137959,ENSG00000100342,ENSG00000156234,ENSG00000196954,ENSG00000101444,ENSG00000111331,ENSG00000074800,ENSG00000105220,ENSG00000158869,ENSG00000145649,ENSG00000100299,ENSG00000013725,ENSG00000163131,ENSG00000125148,ENSG00000067560,ENSG00000132932,ENSG00000197417,ENSG00000213928,ENSG00000133026,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000172270,ENSG00000122877,ENSG00000141736,ENSG00000204592,ENSG00000137965,ENSG00000187608,ENSG00000157873,ENSG00000162676,ENSG00000111863,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000179583,ENSG00000132670,ENSG00000096968,ENSG00000164164,ENSG00000128394,ENSG00000075239,ENSG00000176641,ENSG00000168329,ENSG00000127666,ENSG00000105697,ENSG00000026751,ENSG00000055163,ENSG00000132386,ENSG00000123338,ENSG00000128272,ENSG00000142867,ENSG00000111335,ENSG00000198736,ENSG00000138646,ENSG00000172531,ENSG00000137309,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000127951,ENSG00000131019,ENSG00000131873,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000155090,ENSG00000148218,ENSG00000028137,ENSG00000132256,ENSG00000137193,ENSG00000175104,ENSG00000110218,ENSG00000081985 |
| GO:0044419 | interspecies interaction between organisms | 0.0000000 | 945 | 712 | 84 | 0.1179775 | 0.0888889 | GO:BP | ENSG00000204267,ENSG00000196126,ENSG00000115523,ENSG00000019582,ENSG00000130164,ENSG00000115415,ENSG00000170315,ENSG00000142089,ENSG00000150093,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000176890,ENSG00000111640,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000185201,ENSG00000180644,ENSG00000073008,ENSG00000135114,ENSG00000134321,ENSG00000152465,ENSG00000204264,ENSG00000170312,ENSG00000136436,ENSG00000185885,ENSG00000172116,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000153094,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000116030,ENSG00000072958,ENSG00000132274,ENSG00000166710,ENSG00000152778,ENSG00000185745,ENSG00000147065,ENSG00000100342,ENSG00000111331,ENSG00000136717,ENSG00000100385,ENSG00000198821,ENSG00000067560,ENSG00000114166,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000115267,ENSG00000204256,ENSG00000087302,ENSG00000168961,ENSG00000148175,ENSG00000131747,ENSG00000132182,ENSG00000187608,ENSG00000157873,ENSG00000162676,ENSG00000042753,ENSG00000104765,ENSG00000070831,ENSG00000128394,ENSG00000079999,ENSG00000168329,ENSG00000127666,ENSG00000105697,ENSG00000111335,ENSG00000172531,ENSG00000137309,ENSG00000041357,ENSG00000125354,ENSG00000254087,ENSG00000131019,ENSG00000147168,ENSG00000178685,ENSG00000132256,ENSG00000140575,ENSG00000166794 |
| GO:0045069 | regulation of viral genome replication | 0.0000000 | 100 | 712 | 23 | 0.0323034 | 0.2300000 | GO:BP | ENSG00000142089,ENSG00000232810,ENSG00000185201,ENSG00000135114,ENSG00000134321,ENSG00000185885,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000152778,ENSG00000185745,ENSG00000111331,ENSG00000100298,ENSG00000148175,ENSG00000131747,ENSG00000187608,ENSG00000128394,ENSG00000111335,ENSG00000178685,ENSG00000166794 |
| GO:0044403 | symbiotic process | 0.0000000 | 891 | 712 | 79 | 0.1109551 | 0.0886644 | GO:BP | ENSG00000204267,ENSG00000196126,ENSG00000019582,ENSG00000130164,ENSG00000115415,ENSG00000170315,ENSG00000142089,ENSG00000150093,ENSG00000172757,ENSG00000138795,ENSG00000232810,ENSG00000176890,ENSG00000111640,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000185201,ENSG00000073008,ENSG00000135114,ENSG00000134321,ENSG00000152465,ENSG00000204264,ENSG00000170312,ENSG00000136436,ENSG00000185885,ENSG00000172116,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000153094,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000116030,ENSG00000072958,ENSG00000132274,ENSG00000166710,ENSG00000152778,ENSG00000185745,ENSG00000147065,ENSG00000111331,ENSG00000136717,ENSG00000100385,ENSG00000198821,ENSG00000067560,ENSG00000114166,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000115267,ENSG00000204256,ENSG00000087302,ENSG00000168961,ENSG00000148175,ENSG00000131747,ENSG00000132182,ENSG00000187608,ENSG00000157873,ENSG00000162676,ENSG00000042753,ENSG00000104765,ENSG00000070831,ENSG00000128394,ENSG00000079999,ENSG00000168329,ENSG00000127666,ENSG00000111335,ENSG00000172531,ENSG00000137309,ENSG00000041357,ENSG00000125354,ENSG00000254087,ENSG00000131019,ENSG00000147168,ENSG00000178685,ENSG00000132256,ENSG00000140575,ENSG00000166794 |
| GO:0071310 | cellular response to organic substance | 0.0000000 | 2813 | 712 | 179 | 0.2514045 | 0.0636331 | GO:BP | ENSG00000179344,ENSG00000119922,ENSG00000138496,ENSG00000113721,ENSG00000196126,ENSG00000092010,ENSG00000073861,ENSG00000132530,ENSG00000125347,ENSG00000100321,ENSG00000179218,ENSG00000126709,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000162654,ENSG00000100427,ENSG00000196735,ENSG00000019582,ENSG00000117560,ENSG00000072135,ENSG00000159216,ENSG00000151502,ENSG00000130164,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000186469,ENSG00000069702,ENSG00000100911,ENSG00000164111,ENSG00000113368,ENSG00000101057,ENSG00000177156,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000142089,ENSG00000169252,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000120057,ENSG00000127947,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000105409,ENSG00000123609,ENSG00000096996,ENSG00000172757,ENSG00000138795,ENSG00000110090,ENSG00000111537,ENSG00000102554,ENSG00000232810,ENSG00000183691,ENSG00000117228,ENSG00000204397,ENSG00000111640,ENSG00000134352,ENSG00000117226,ENSG00000185201,ENSG00000116288,ENSG00000111602,ENSG00000135114,ENSG00000134321,ENSG00000169855,ENSG00000103966,ENSG00000204264,ENSG00000188191,ENSG00000130402,ENSG00000155846,ENSG00000185885,ENSG00000185651,ENSG00000070018,ENSG00000165949,ENSG00000055332,ENSG00000153094,ENSG00000123416,ENSG00000065135,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000044574,ENSG00000116030,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000132274,ENSG00000166710,ENSG00000111229,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000180667,ENSG00000138071,ENSG00000166598,ENSG00000148730,ENSG00000156234,ENSG00000196954,ENSG00000185650,ENSG00000111331,ENSG00000158869,ENSG00000013725,ENSG00000163131,ENSG00000100385,ENSG00000125148,ENSG00000131504,ENSG00000011485,ENSG00000067560,ENSG00000197417,ENSG00000213928,ENSG00000114166,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000115339,ENSG00000122877,ENSG00000141736,ENSG00000204592,ENSG00000103994,ENSG00000213626,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000162676,ENSG00000111863,ENSG00000106462,ENSG00000070831,ENSG00000172936,ENSG00000179583,ENSG00000132670,ENSG00000075624,ENSG00000096968,ENSG00000164164,ENSG00000079999,ENSG00000170837,ENSG00000165527,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000105697,ENSG00000127022,ENSG00000148908,ENSG00000138617,ENSG00000055163,ENSG00000090520,ENSG00000132386,ENSG00000128272,ENSG00000142867,ENSG00000111335,ENSG00000119318,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000213366,ENSG00000197409,ENSG00000137312,ENSG00000143321,ENSG00000155090,ENSG00000148218,ENSG00000147168,ENSG00000177674,ENSG00000135960,ENSG00000028137,ENSG00000132256,ENSG00000140575,ENSG00000137193,ENSG00000175104,ENSG00000112759,ENSG00000081985 |
| GO:0045071 | negative regulation of viral genome replication | 0.0000000 | 63 | 712 | 18 | 0.0252809 | 0.2857143 | GO:BP | ENSG00000142089,ENSG00000232810,ENSG00000185201,ENSG00000135114,ENSG00000134321,ENSG00000185885,ENSG00000055332,ENSG00000239713,ENSG00000157601,ENSG00000089127,ENSG00000152778,ENSG00000185745,ENSG00000111331,ENSG00000100298,ENSG00000187608,ENSG00000128394,ENSG00000111335,ENSG00000178685 |
| GO:0045321 | leukocyte activation | 0.0000000 | 1305 | 712 | 102 | 0.1432584 | 0.0781609 | GO:BP | ENSG00000172057,ENSG00000004468,ENSG00000179344,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000100321,ENSG00000135077,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000130164,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000160654,ENSG00000137265,ENSG00000117984,ENSG00000150093,ENSG00000136167,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000134352,ENSG00000153563,ENSG00000005844,ENSG00000196230,ENSG00000134765,ENSG00000180644,ENSG00000134321,ENSG00000137563,ENSG00000077984,ENSG00000122223,ENSG00000172116,ENSG00000169230,ENSG00000213281,ENSG00000123131,ENSG00000204472,ENSG00000064666,ENSG00000072958,ENSG00000166710,ENSG00000147065,ENSG00000138071,ENSG00000131236,ENSG00000110448,ENSG00000021355,ENSG00000185650,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000168421,ENSG00000100299,ENSG00000013725,ENSG00000163131,ENSG00000131504,ENSG00000184916,ENSG00000067560,ENSG00000197417,ENSG00000172794,ENSG00000204642,ENSG00000168961,ENSG00000122122,ENSG00000165283,ENSG00000148175,ENSG00000141736,ENSG00000204592,ENSG00000174371,ENSG00000167286,ENSG00000157873,ENSG00000153310,ENSG00000070831,ENSG00000172936,ENSG00000171302,ENSG00000147234,ENSG00000096968,ENSG00000127666,ENSG00000139370,ENSG00000223496,ENSG00000026751,ENSG00000116670,ENSG00000123338,ENSG00000142867,ENSG00000140284,ENSG00000254087,ENSG00000160255,ENSG00000140319,ENSG00000127951,ENSG00000101082,ENSG00000131019,ENSG00000198851,ENSG00000196839,ENSG00000148218,ENSG00000242574,ENSG00000028137,ENSG00000147889,ENSG00000140575,ENSG00000175104 |
| GO:0046649 | lymphocyte activation | 0.0000000 | 754 | 712 | 70 | 0.0983146 | 0.0928382 | GO:BP | ENSG00000004468,ENSG00000179344,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000160654,ENSG00000137265,ENSG00000150093,ENSG00000136167,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000189430,ENSG00000134352,ENSG00000153563,ENSG00000005844,ENSG00000180644,ENSG00000134321,ENSG00000122223,ENSG00000172116,ENSG00000169230,ENSG00000204472,ENSG00000166710,ENSG00000147065,ENSG00000110448,ENSG00000185650,ENSG00000158869,ENSG00000168421,ENSG00000013725,ENSG00000184916,ENSG00000067560,ENSG00000204642,ENSG00000168961,ENSG00000122122,ENSG00000165283,ENSG00000141736,ENSG00000204592,ENSG00000174371,ENSG00000167286,ENSG00000157873,ENSG00000153310,ENSG00000070831,ENSG00000172936,ENSG00000127666,ENSG00000223496,ENSG00000026751,ENSG00000116670,ENSG00000123338,ENSG00000142867,ENSG00000254087,ENSG00000160255,ENSG00000127951,ENSG00000101082,ENSG00000131019,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000028137,ENSG00000147889,ENSG00000175104 |
| GO:0050863 | regulation of T cell activation | 0.0000000 | 330 | 712 | 41 | 0.0575843 | 0.1242424 | GO:BP | ENSG00000179344,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000137265,ENSG00000096996,ENSG00000111537,ENSG00000134352,ENSG00000169230,ENSG00000204472,ENSG00000110448,ENSG00000168421,ENSG00000013725,ENSG00000067560,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000153310,ENSG00000070831,ENSG00000123338,ENSG00000142867,ENSG00000254087,ENSG00000127951,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000028137,ENSG00000147889,ENSG00000175104 |
| GO:0070887 | cellular response to chemical stimulus | 0.0000000 | 3418 | 712 | 205 | 0.2879213 | 0.0599766 | GO:BP | ENSG00000179344,ENSG00000119922,ENSG00000138496,ENSG00000113721,ENSG00000196126,ENSG00000092010,ENSG00000073861,ENSG00000132530,ENSG00000125347,ENSG00000100321,ENSG00000109956,ENSG00000179218,ENSG00000126709,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000162654,ENSG00000100427,ENSG00000134184,ENSG00000196735,ENSG00000019582,ENSG00000117560,ENSG00000072135,ENSG00000159216,ENSG00000151502,ENSG00000130164,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000186469,ENSG00000069702,ENSG00000100911,ENSG00000221866,ENSG00000164111,ENSG00000113368,ENSG00000101057,ENSG00000177156,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000142089,ENSG00000169252,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000120057,ENSG00000127947,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000105409,ENSG00000123609,ENSG00000173848,ENSG00000096996,ENSG00000125249,ENSG00000172757,ENSG00000138795,ENSG00000110090,ENSG00000111537,ENSG00000102554,ENSG00000232810,ENSG00000183691,ENSG00000117228,ENSG00000204397,ENSG00000108179,ENSG00000111640,ENSG00000118777,ENSG00000134352,ENSG00000132646,ENSG00000117226,ENSG00000185201,ENSG00000116288,ENSG00000111602,ENSG00000135114,ENSG00000134321,ENSG00000169855,ENSG00000103966,ENSG00000023572,ENSG00000204264,ENSG00000188191,ENSG00000130402,ENSG00000170312,ENSG00000155846,ENSG00000185885,ENSG00000185651,ENSG00000164830,ENSG00000117394,ENSG00000070018,ENSG00000165949,ENSG00000055332,ENSG00000153094,ENSG00000123416,ENSG00000065135,ENSG00000213445,ENSG00000104687,ENSG00000123131,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000152256,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000044574,ENSG00000116030,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000132274,ENSG00000166710,ENSG00000111229,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000180667,ENSG00000129422,ENSG00000138071,ENSG00000166598,ENSG00000148730,ENSG00000156234,ENSG00000196954,ENSG00000185650,ENSG00000111331,ENSG00000074800,ENSG00000158869,ENSG00000013725,ENSG00000163131,ENSG00000100385,ENSG00000125148,ENSG00000131504,ENSG00000011485,ENSG00000067560,ENSG00000197417,ENSG00000213928,ENSG00000114166,ENSG00000165304,ENSG00000134202,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000115339,ENSG00000122877,ENSG00000141736,ENSG00000204592,ENSG00000103994,ENSG00000213626,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000162676,ENSG00000111863,ENSG00000106462,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000179583,ENSG00000132670,ENSG00000075624,ENSG00000096968,ENSG00000164164,ENSG00000079999,ENSG00000170837,ENSG00000165527,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000105697,ENSG00000127022,ENSG00000148908,ENSG00000138617,ENSG00000125648,ENSG00000055163,ENSG00000090520,ENSG00000132386,ENSG00000123338,ENSG00000128272,ENSG00000142867,ENSG00000111335,ENSG00000126432,ENSG00000119318,ENSG00000168765,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000213366,ENSG00000177076,ENSG00000197409,ENSG00000137312,ENSG00000143321,ENSG00000155090,ENSG00000148218,ENSG00000147168,ENSG00000177674,ENSG00000135960,ENSG00000028137,ENSG00000132256,ENSG00000140575,ENSG00000137193,ENSG00000175104,ENSG00000112759,ENSG00000081985 |
| GO:1903037 | regulation of leukocyte cell-cell adhesion | 0.0000000 | 322 | 712 | 40 | 0.0561798 | 0.1242236 | GO:BP | ENSG00000179344,ENSG00000117281,ENSG00000196126,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000096996,ENSG00000111537,ENSG00000232810,ENSG00000134352,ENSG00000204472,ENSG00000110448,ENSG00000168421,ENSG00000013725,ENSG00000067560,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000111863,ENSG00000153310,ENSG00000070831,ENSG00000123338,ENSG00000142867,ENSG00000254087,ENSG00000160255,ENSG00000127951,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000147889,ENSG00000175104 |
| GO:0019079 | viral genome replication | 0.0000000 | 128 | 712 | 24 | 0.0337079 | 0.1875000 | GO:BP | ENSG00000142089,ENSG00000232810,ENSG00000185201,ENSG00000135114,ENSG00000134321,ENSG00000185885,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000152778,ENSG00000185745,ENSG00000111331,ENSG00000100298,ENSG00000148175,ENSG00000131747,ENSG00000187608,ENSG00000070831,ENSG00000128394,ENSG00000111335,ENSG00000178685,ENSG00000166794 |
| GO:0001775 | cell activation | 0.0000000 | 1465 | 712 | 108 | 0.1516854 | 0.0737201 | GO:BP | ENSG00000172057,ENSG00000004468,ENSG00000179344,ENSG00000113721,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000100321,ENSG00000135077,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000130164,ENSG00000186469,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000160654,ENSG00000196924,ENSG00000137265,ENSG00000117984,ENSG00000150093,ENSG00000136167,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000102554,ENSG00000189430,ENSG00000232810,ENSG00000134352,ENSG00000153563,ENSG00000005844,ENSG00000196230,ENSG00000134765,ENSG00000180644,ENSG00000134321,ENSG00000137563,ENSG00000077984,ENSG00000122223,ENSG00000172116,ENSG00000169230,ENSG00000213281,ENSG00000123131,ENSG00000204472,ENSG00000064666,ENSG00000072958,ENSG00000166710,ENSG00000147065,ENSG00000138071,ENSG00000131236,ENSG00000110448,ENSG00000021355,ENSG00000185650,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000168421,ENSG00000100299,ENSG00000013725,ENSG00000163131,ENSG00000131504,ENSG00000184916,ENSG00000067560,ENSG00000197417,ENSG00000213719,ENSG00000172794,ENSG00000204642,ENSG00000168961,ENSG00000122122,ENSG00000165283,ENSG00000148175,ENSG00000141736,ENSG00000204592,ENSG00000174371,ENSG00000167286,ENSG00000157873,ENSG00000153310,ENSG00000070831,ENSG00000172936,ENSG00000171302,ENSG00000147234,ENSG00000075624,ENSG00000096968,ENSG00000127666,ENSG00000139370,ENSG00000223496,ENSG00000026751,ENSG00000116670,ENSG00000123338,ENSG00000142867,ENSG00000140284,ENSG00000254087,ENSG00000160255,ENSG00000140319,ENSG00000127951,ENSG00000101082,ENSG00000131019,ENSG00000198851,ENSG00000196839,ENSG00000148218,ENSG00000242574,ENSG00000028137,ENSG00000147889,ENSG00000140575,ENSG00000175104 |
| GO:0030155 | regulation of cell adhesion | 0.0000000 | 721 | 712 | 66 | 0.0926966 | 0.0915395 | GO:BP | ENSG00000179344,ENSG00000117281,ENSG00000196126,ENSG00000248905,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000179218,ENSG00000135077,ENSG00000147459,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000221866,ENSG00000205336,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000196924,ENSG00000118193,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000179051,ENSG00000112139,ENSG00000232810,ENSG00000117228,ENSG00000134352,ENSG00000130402,ENSG00000213445,ENSG00000163520,ENSG00000148400,ENSG00000204472,ENSG00000110448,ENSG00000111348,ENSG00000156234,ENSG00000168421,ENSG00000013725,ENSG00000184916,ENSG00000067560,ENSG00000168961,ENSG00000122122,ENSG00000173517,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000111863,ENSG00000153310,ENSG00000070831,ENSG00000079691,ENSG00000096968,ENSG00000116670,ENSG00000123338,ENSG00000142867,ENSG00000254087,ENSG00000160255,ENSG00000177076,ENSG00000127951,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000147889,ENSG00000140575,ENSG00000175104,ENSG00000111859 |
| GO:1903900 | regulation of viral life cycle | 0.0000001 | 152 | 712 | 26 | 0.0365169 | 0.1710526 | GO:BP | ENSG00000019582,ENSG00000142089,ENSG00000232810,ENSG00000185201,ENSG00000135114,ENSG00000134321,ENSG00000185885,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000152778,ENSG00000185745,ENSG00000111331,ENSG00000100298,ENSG00000168961,ENSG00000148175,ENSG00000131747,ENSG00000187608,ENSG00000128394,ENSG00000111335,ENSG00000178685,ENSG00000132256,ENSG00000166794 |
| GO:0051704 | multi-organism process | 0.0000001 | 3072 | 712 | 187 | 0.2626404 | 0.0608724 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000179344,ENSG00000119922,ENSG00000138496,ENSG00000204267,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000073605,ENSG00000073861,ENSG00000132530,ENSG00000125347,ENSG00000179218,ENSG00000115523,ENSG00000126709,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000162654,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000151502,ENSG00000130164,ENSG00000115415,ENSG00000119917,ENSG00000155629,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000117632,ENSG00000142089,ENSG00000196924,ENSG00000137265,ENSG00000112029,ENSG00000150093,ENSG00000123609,ENSG00000096996,ENSG00000211698,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000134539,ENSG00000117228,ENSG00000176890,ENSG00000204397,ENSG00000111640,ENSG00000134352,ENSG00000139626,ENSG00000167914,ENSG00000132646,ENSG00000100380,ENSG00000128335,ENSG00000117226,ENSG00000185201,ENSG00000116288,ENSG00000196230,ENSG00000180644,ENSG00000073008,ENSG00000135114,ENSG00000134321,ENSG00000249437,ENSG00000100918,ENSG00000152465,ENSG00000138642,ENSG00000204264,ENSG00000105011,ENSG00000131018,ENSG00000170312,ENSG00000122223,ENSG00000136436,ENSG00000185885,ENSG00000117394,ENSG00000172116,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000153094,ENSG00000213281,ENSG00000123131,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000204472,ENSG00000163041,ENSG00000116030,ENSG00000072958,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000152778,ENSG00000185745,ENSG00000147065,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000111348,ENSG00000137959,ENSG00000148730,ENSG00000100342,ENSG00000156234,ENSG00000196954,ENSG00000111331,ENSG00000074800,ENSG00000158869,ENSG00000145649,ENSG00000136717,ENSG00000100299,ENSG00000013725,ENSG00000163131,ENSG00000100385,ENSG00000130005,ENSG00000125148,ENSG00000184916,ENSG00000198821,ENSG00000067560,ENSG00000197417,ENSG00000213928,ENSG00000114166,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000204642,ENSG00000115267,ENSG00000204256,ENSG00000087302,ENSG00000168961,ENSG00000172270,ENSG00000148175,ENSG00000131747,ENSG00000204592,ENSG00000132182,ENSG00000137965,ENSG00000187608,ENSG00000157873,ENSG00000162676,ENSG00000042753,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000101079,ENSG00000179583,ENSG00000066279,ENSG00000096968,ENSG00000164164,ENSG00000128394,ENSG00000079999,ENSG00000168329,ENSG00000127666,ENSG00000105697,ENSG00000026751,ENSG00000142867,ENSG00000111335,ENSG00000198736,ENSG00000138646,ENSG00000119318,ENSG00000172531,ENSG00000137309,ENSG00000041357,ENSG00000125354,ENSG00000254087,ENSG00000160255,ENSG00000127951,ENSG00000131019,ENSG00000137312,ENSG00000196839,ENSG00000148218,ENSG00000147168,ENSG00000028137,ENSG00000178685,ENSG00000132256,ENSG00000140575,ENSG00000111450,ENSG00000175104,ENSG00000166794,ENSG00000081985 |
| GO:0002684 | positive regulation of immune system process | 0.0000001 | 1199 | 712 | 93 | 0.1306180 | 0.0775646 | GO:BP | ENSG00000004468,ENSG00000179344,ENSG00000138496,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000179218,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000089692,ENSG00000196735,ENSG00000019582,ENSG00000203747,ENSG00000159216,ENSG00000115415,ENSG00000155629,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000105639,ENSG00000160654,ENSG00000137265,ENSG00000186470,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000134352,ENSG00000116288,ENSG00000073008,ENSG00000134321,ENSG00000204264,ENSG00000155846,ENSG00000122223,ENSG00000213281,ENSG00000204472,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000163823,ENSG00000138071,ENSG00000166598,ENSG00000110448,ENSG00000156234,ENSG00000185650,ENSG00000105220,ENSG00000158869,ENSG00000071994,ENSG00000168421,ENSG00000013725,ENSG00000163131,ENSG00000198821,ENSG00000067560,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000122122,ENSG00000165283,ENSG00000204592,ENSG00000167286,ENSG00000187608,ENSG00000157873,ENSG00000162676,ENSG00000153310,ENSG00000070831,ENSG00000172936,ENSG00000075624,ENSG00000164164,ENSG00000168329,ENSG00000127666,ENSG00000223496,ENSG00000116670,ENSG00000055163,ENSG00000123338,ENSG00000142867,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000101082,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000155090,ENSG00000242574,ENSG00000132256,ENSG00000175104 |
| GO:1903039 | positive regulation of leukocyte cell-cell adhesion | 0.0000001 | 230 | 712 | 32 | 0.0449438 | 0.1391304 | GO:BP | ENSG00000179344,ENSG00000117281,ENSG00000163599,ENSG00000135077,ENSG00000019582,ENSG00000159216,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000096996,ENSG00000111537,ENSG00000232810,ENSG00000134352,ENSG00000204472,ENSG00000110448,ENSG00000168421,ENSG00000013725,ENSG00000067560,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000157873,ENSG00000153310,ENSG00000070831,ENSG00000123338,ENSG00000142867,ENSG00000254087,ENSG00000160255,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000175104 |
| GO:0006915 | apoptotic process | 0.0000001 | 2006 | 712 | 134 | 0.1882022 | 0.0667996 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000119922,ENSG00000100450,ENSG00000113721,ENSG00000117281,ENSG00000072110,ENSG00000163599,ENSG00000132530,ENSG00000125347,ENSG00000179218,ENSG00000126709,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000144354,ENSG00000115415,ENSG00000119917,ENSG00000164111,ENSG00000101057,ENSG00000170315,ENSG00000156970,ENSG00000105639,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000146674,ENSG00000118193,ENSG00000120057,ENSG00000117984,ENSG00000150093,ENSG00000173848,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000183691,ENSG00000134308,ENSG00000204397,ENSG00000108179,ENSG00000111640,ENSG00000134352,ENSG00000167914,ENSG00000084092,ENSG00000116288,ENSG00000180644,ENSG00000103202,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000023572,ENSG00000156463,ENSG00000143543,ENSG00000130402,ENSG00000071205,ENSG00000170312,ENSG00000164830,ENSG00000141576,ENSG00000070018,ENSG00000165949,ENSG00000055332,ENSG00000169230,ENSG00000153094,ENSG00000065135,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000152256,ENSG00000204472,ENSG00000089685,ENSG00000044574,ENSG00000007968,ENSG00000163545,ENSG00000166598,ENSG00000110448,ENSG00000129675,ENSG00000118971,ENSG00000196954,ENSG00000185650,ENSG00000074800,ENSG00000105220,ENSG00000158869,ENSG00000145649,ENSG00000136717,ENSG00000071994,ENSG00000158006,ENSG00000100385,ENSG00000184916,ENSG00000067560,ENSG00000127952,ENSG00000189283,ENSG00000165304,ENSG00000185507,ENSG00000006625,ENSG00000168961,ENSG00000131747,ENSG00000132792,ENSG00000103495,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000112996,ENSG00000171169,ENSG00000178719,ENSG00000197043,ENSG00000096968,ENSG00000176641,ENSG00000165527,ENSG00000105612,ENSG00000168329,ENSG00000127666,ENSG00000196072,ENSG00000055163,ENSG00000185880,ENSG00000123338,ENSG00000128272,ENSG00000134049,ENSG00000142867,ENSG00000114126,ENSG00000126432,ENSG00000124155,ENSG00000172531,ENSG00000254087,ENSG00000160255,ENSG00000177076,ENSG00000172667,ENSG00000198851,ENSG00000196839,ENSG00000135960,ENSG00000028137,ENSG00000147889,ENSG00000137193,ENSG00000175104,ENSG00000127084 |
| GO:0022407 | regulation of cell-cell adhesion | 0.0000001 | 426 | 712 | 46 | 0.0646067 | 0.1079812 | GO:BP | ENSG00000179344,ENSG00000117281,ENSG00000196126,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000112139,ENSG00000232810,ENSG00000134352,ENSG00000204472,ENSG00000110448,ENSG00000156234,ENSG00000168421,ENSG00000013725,ENSG00000067560,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000111863,ENSG00000153310,ENSG00000070831,ENSG00000096968,ENSG00000116670,ENSG00000123338,ENSG00000142867,ENSG00000254087,ENSG00000160255,ENSG00000127951,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000147889,ENSG00000175104 |
| GO:0002478 | antigen processing and presentation of exogenous peptide antigen | 0.0000002 | 173 | 712 | 27 | 0.0379213 | 0.1560694 | GO:BP | ENSG00000179344,ENSG00000204267,ENSG00000196126,ENSG00000092010,ENSG00000179218,ENSG00000089692,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000167004,ENSG00000117984,ENSG00000138160,ENSG00000204264,ENSG00000072958,ENSG00000166710,ENSG00000158869,ENSG00000163131,ENSG00000204642,ENSG00000204592,ENSG00000042753,ENSG00000127022,ENSG00000041357,ENSG00000242574,ENSG00000175104 |
| GO:0050870 | positive regulation of T cell activation | 0.0000002 | 210 | 712 | 30 | 0.0421348 | 0.1428571 | GO:BP | ENSG00000179344,ENSG00000117281,ENSG00000163599,ENSG00000135077,ENSG00000019582,ENSG00000159216,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000096996,ENSG00000111537,ENSG00000134352,ENSG00000204472,ENSG00000110448,ENSG00000168421,ENSG00000013725,ENSG00000067560,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000157873,ENSG00000153310,ENSG00000070831,ENSG00000123338,ENSG00000142867,ENSG00000254087,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000175104 |
| GO:1903901 | negative regulation of viral life cycle | 0.0000002 | 88 | 712 | 19 | 0.0266854 | 0.2159091 | GO:BP | ENSG00000142089,ENSG00000232810,ENSG00000185201,ENSG00000135114,ENSG00000134321,ENSG00000185885,ENSG00000055332,ENSG00000239713,ENSG00000157601,ENSG00000089127,ENSG00000152778,ENSG00000185745,ENSG00000111331,ENSG00000100298,ENSG00000187608,ENSG00000128394,ENSG00000111335,ENSG00000178685,ENSG00000132256 |
| GO:0050778 | positive regulation of immune response | 0.0000002 | 892 | 712 | 74 | 0.1039326 | 0.0829596 | GO:BP | ENSG00000004468,ENSG00000179344,ENSG00000138496,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000089692,ENSG00000196735,ENSG00000019582,ENSG00000203747,ENSG00000159216,ENSG00000155629,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000160654,ENSG00000137265,ENSG00000186470,ENSG00000096996,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000134352,ENSG00000116288,ENSG00000073008,ENSG00000134321,ENSG00000204264,ENSG00000213281,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000138071,ENSG00000166598,ENSG00000158869,ENSG00000163131,ENSG00000198821,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000122122,ENSG00000165283,ENSG00000204592,ENSG00000167286,ENSG00000157873,ENSG00000162676,ENSG00000153310,ENSG00000070831,ENSG00000172936,ENSG00000075624,ENSG00000164164,ENSG00000127666,ENSG00000223496,ENSG00000116670,ENSG00000055163,ENSG00000123338,ENSG00000142867,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000101082,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000132256,ENSG00000175104 |
| GO:0043903 | regulation of symbiosis, encompassing mutualism through parasitism | 0.0000002 | 226 | 712 | 31 | 0.0435393 | 0.1371681 | GO:BP | ENSG00000019582,ENSG00000115415,ENSG00000142089,ENSG00000172757,ENSG00000138795,ENSG00000232810,ENSG00000111640,ENSG00000185201,ENSG00000135114,ENSG00000134321,ENSG00000185885,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000153094,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000152778,ENSG00000185745,ENSG00000111331,ENSG00000100298,ENSG00000168961,ENSG00000148175,ENSG00000131747,ENSG00000187608,ENSG00000128394,ENSG00000111335,ENSG00000178685,ENSG00000132256,ENSG00000166794 |
| GO:0045785 | positive regulation of cell adhesion | 0.0000002 | 422 | 712 | 45 | 0.0632022 | 0.1066351 | GO:BP | ENSG00000179344,ENSG00000117281,ENSG00000248905,ENSG00000163599,ENSG00000179218,ENSG00000135077,ENSG00000147459,ENSG00000019582,ENSG00000159216,ENSG00000205336,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000196924,ENSG00000096996,ENSG00000111537,ENSG00000232810,ENSG00000134352,ENSG00000163520,ENSG00000204472,ENSG00000110448,ENSG00000156234,ENSG00000168421,ENSG00000013725,ENSG00000067560,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000153310,ENSG00000070831,ENSG00000079691,ENSG00000096968,ENSG00000123338,ENSG00000142867,ENSG00000254087,ENSG00000160255,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000140575,ENSG00000175104,ENSG00000111859 |
| GO:0010033 | response to organic substance | 0.0000003 | 3421 | 712 | 200 | 0.2808989 | 0.0584624 | GO:BP | ENSG00000004468,ENSG00000179344,ENSG00000119922,ENSG00000138496,ENSG00000113721,ENSG00000196126,ENSG00000092010,ENSG00000073861,ENSG00000132530,ENSG00000125347,ENSG00000100321,ENSG00000179218,ENSG00000126709,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000162654,ENSG00000100427,ENSG00000196735,ENSG00000019582,ENSG00000117560,ENSG00000072135,ENSG00000159216,ENSG00000151502,ENSG00000160014,ENSG00000130164,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000186469,ENSG00000069702,ENSG00000100911,ENSG00000164111,ENSG00000113368,ENSG00000101057,ENSG00000177156,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000142089,ENSG00000169252,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000120057,ENSG00000127947,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000105409,ENSG00000123609,ENSG00000096996,ENSG00000172757,ENSG00000138795,ENSG00000110090,ENSG00000111537,ENSG00000102554,ENSG00000099194,ENSG00000232810,ENSG00000183691,ENSG00000117228,ENSG00000176890,ENSG00000204397,ENSG00000111640,ENSG00000134352,ENSG00000132646,ENSG00000117226,ENSG00000185201,ENSG00000116288,ENSG00000111602,ENSG00000135114,ENSG00000134321,ENSG00000169855,ENSG00000103966,ENSG00000023572,ENSG00000137563,ENSG00000204264,ENSG00000188191,ENSG00000130402,ENSG00000170312,ENSG00000155846,ENSG00000136436,ENSG00000185885,ENSG00000185651,ENSG00000117394,ENSG00000070018,ENSG00000165949,ENSG00000055332,ENSG00000242372,ENSG00000153094,ENSG00000123416,ENSG00000065135,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000044574,ENSG00000116030,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000111229,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000180667,ENSG00000138071,ENSG00000166598,ENSG00000148730,ENSG00000156234,ENSG00000196954,ENSG00000185650,ENSG00000111331,ENSG00000105220,ENSG00000158869,ENSG00000100299,ENSG00000013725,ENSG00000163131,ENSG00000170881,ENSG00000100385,ENSG00000125148,ENSG00000131504,ENSG00000011485,ENSG00000067560,ENSG00000197417,ENSG00000213928,ENSG00000114166,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000115339,ENSG00000172270,ENSG00000122877,ENSG00000141736,ENSG00000204592,ENSG00000103994,ENSG00000213626,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000162676,ENSG00000111863,ENSG00000106462,ENSG00000070831,ENSG00000172936,ENSG00000179583,ENSG00000132670,ENSG00000075624,ENSG00000096968,ENSG00000164164,ENSG00000075239,ENSG00000079999,ENSG00000170837,ENSG00000165527,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000105697,ENSG00000127022,ENSG00000148908,ENSG00000138617,ENSG00000055163,ENSG00000090520,ENSG00000132386,ENSG00000049239,ENSG00000128272,ENSG00000142867,ENSG00000111335,ENSG00000119318,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000213366,ENSG00000177076,ENSG00000197409,ENSG00000137312,ENSG00000196839,ENSG00000143321,ENSG00000155090,ENSG00000148218,ENSG00000147168,ENSG00000177674,ENSG00000135960,ENSG00000028137,ENSG00000132256,ENSG00000140575,ENSG00000137193,ENSG00000175104,ENSG00000110218,ENSG00000112759,ENSG00000081985 |
| GO:0043901 | negative regulation of multi-organism process | 0.0000003 | 227 | 712 | 31 | 0.0435393 | 0.1365639 | GO:BP | ENSG00000179218,ENSG00000135077,ENSG00000115415,ENSG00000142089,ENSG00000123609,ENSG00000232810,ENSG00000204397,ENSG00000185201,ENSG00000135114,ENSG00000134321,ENSG00000185885,ENSG00000055332,ENSG00000239713,ENSG00000123131,ENSG00000157601,ENSG00000089127,ENSG00000152778,ENSG00000185745,ENSG00000111348,ENSG00000111331,ENSG00000100298,ENSG00000204642,ENSG00000168961,ENSG00000204592,ENSG00000187608,ENSG00000128394,ENSG00000111335,ENSG00000127951,ENSG00000196839,ENSG00000178685,ENSG00000132256 |
| GO:0048002 | antigen processing and presentation of peptide antigen | 0.0000003 | 192 | 712 | 28 | 0.0393258 | 0.1458333 | GO:BP | ENSG00000164308,ENSG00000179344,ENSG00000204267,ENSG00000196126,ENSG00000092010,ENSG00000179218,ENSG00000089692,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000167004,ENSG00000117984,ENSG00000138160,ENSG00000204264,ENSG00000072958,ENSG00000166710,ENSG00000158869,ENSG00000163131,ENSG00000204642,ENSG00000204592,ENSG00000042753,ENSG00000127022,ENSG00000041357,ENSG00000242574,ENSG00000175104 |
| GO:0019884 | antigen processing and presentation of exogenous antigen | 0.0000003 | 180 | 712 | 27 | 0.0379213 | 0.1500000 | GO:BP | ENSG00000179344,ENSG00000204267,ENSG00000196126,ENSG00000092010,ENSG00000179218,ENSG00000089692,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000167004,ENSG00000117984,ENSG00000138160,ENSG00000204264,ENSG00000072958,ENSG00000166710,ENSG00000158869,ENSG00000163131,ENSG00000204642,ENSG00000204592,ENSG00000042753,ENSG00000127022,ENSG00000041357,ENSG00000242574,ENSG00000175104 |
| GO:0022409 | positive regulation of cell-cell adhesion | 0.0000005 | 273 | 712 | 34 | 0.0477528 | 0.1245421 | GO:BP | ENSG00000179344,ENSG00000117281,ENSG00000163599,ENSG00000135077,ENSG00000019582,ENSG00000159216,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000096996,ENSG00000111537,ENSG00000232810,ENSG00000134352,ENSG00000204472,ENSG00000110448,ENSG00000156234,ENSG00000168421,ENSG00000013725,ENSG00000067560,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000157873,ENSG00000153310,ENSG00000070831,ENSG00000123338,ENSG00000142867,ENSG00000254087,ENSG00000160255,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000175104 |
| GO:0048525 | negative regulation of viral process | 0.0000006 | 105 | 712 | 20 | 0.0280899 | 0.1904762 | GO:BP | ENSG00000115415,ENSG00000142089,ENSG00000232810,ENSG00000185201,ENSG00000135114,ENSG00000134321,ENSG00000185885,ENSG00000055332,ENSG00000239713,ENSG00000157601,ENSG00000089127,ENSG00000152778,ENSG00000185745,ENSG00000111331,ENSG00000100298,ENSG00000187608,ENSG00000128394,ENSG00000111335,ENSG00000178685,ENSG00000132256 |
| GO:0098609 | cell-cell adhesion | 0.0000006 | 866 | 712 | 71 | 0.0997191 | 0.0819861 | GO:BP | ENSG00000179344,ENSG00000117281,ENSG00000196126,ENSG00000073861,ENSG00000156886,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000173482,ENSG00000091129,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000196924,ENSG00000150093,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000112139,ENSG00000232810,ENSG00000134352,ENSG00000139626,ENSG00000005844,ENSG00000167123,ENSG00000134765,ENSG00000073008,ENSG00000169855,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000204472,ENSG00000147065,ENSG00000110448,ENSG00000156234,ENSG00000185650,ENSG00000181467,ENSG00000168421,ENSG00000013725,ENSG00000067560,ENSG00000213719,ENSG00000075340,ENSG00000168961,ENSG00000122122,ENSG00000172270,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000111863,ENSG00000153310,ENSG00000070831,ENSG00000075624,ENSG00000096968,ENSG00000168329,ENSG00000116670,ENSG00000055163,ENSG00000123338,ENSG00000142867,ENSG00000172531,ENSG00000254087,ENSG00000160255,ENSG00000127951,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000147889,ENSG00000175104,ENSG00000114631 |
| GO:0019058 | viral life cycle | 0.0000006 | 333 | 712 | 38 | 0.0533708 | 0.1141141 | GO:BP | ENSG00000196126,ENSG00000019582,ENSG00000130164,ENSG00000170315,ENSG00000142089,ENSG00000150093,ENSG00000232810,ENSG00000139626,ENSG00000185201,ENSG00000073008,ENSG00000135114,ENSG00000134321,ENSG00000152465,ENSG00000170312,ENSG00000185885,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000152778,ENSG00000185745,ENSG00000111331,ENSG00000149294,ENSG00000100298,ENSG00000168961,ENSG00000148175,ENSG00000131747,ENSG00000132182,ENSG00000187608,ENSG00000157873,ENSG00000070831,ENSG00000128394,ENSG00000111335,ENSG00000178685,ENSG00000132256,ENSG00000166794 |
| GO:0002520 | immune system development | 0.0000006 | 1009 | 712 | 79 | 0.1109551 | 0.0782953 | GO:BP | ENSG00000179344,ENSG00000113721,ENSG00000176083,ENSG00000092010,ENSG00000072110,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000115415,ENSG00000069702,ENSG00000100911,ENSG00000105639,ENSG00000160654,ENSG00000137265,ENSG00000157216,ENSG00000150093,ENSG00000096996,ENSG00000172331,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000153563,ENSG00000134321,ENSG00000138642,ENSG00000204264,ENSG00000051341,ENSG00000011426,ENSG00000160219,ENSG00000155846,ENSG00000055332,ENSG00000242372,ENSG00000169230,ENSG00000153094,ENSG00000148400,ENSG00000163041,ENSG00000064666,ENSG00000166710,ENSG00000163823,ENSG00000185650,ENSG00000158869,ENSG00000071994,ENSG00000168421,ENSG00000184916,ENSG00000067560,ENSG00000114166,ENSG00000165304,ENSG00000075340,ENSG00000185507,ENSG00000168961,ENSG00000122122,ENSG00000131747,ENSG00000141736,ENSG00000204592,ENSG00000132792,ENSG00000174371,ENSG00000167286,ENSG00000187608,ENSG00000162676,ENSG00000070831,ENSG00000096968,ENSG00000105612,ENSG00000223496,ENSG00000116670,ENSG00000123338,ENSG00000041357,ENSG00000254087,ENSG00000091127,ENSG00000127951,ENSG00000197409,ENSG00000198851,ENSG00000196839,ENSG00000155090,ENSG00000147889,ENSG00000137193,ENSG00000175104 |
| GO:0012501 | programmed cell death | 0.0000006 | 2152 | 712 | 138 | 0.1938202 | 0.0641264 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000119922,ENSG00000100450,ENSG00000113721,ENSG00000117281,ENSG00000072110,ENSG00000073605,ENSG00000163599,ENSG00000132530,ENSG00000125347,ENSG00000179218,ENSG00000126709,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000144354,ENSG00000115415,ENSG00000119917,ENSG00000164111,ENSG00000101057,ENSG00000170315,ENSG00000156970,ENSG00000105639,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000146674,ENSG00000118193,ENSG00000120057,ENSG00000117984,ENSG00000150093,ENSG00000173848,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000183691,ENSG00000134308,ENSG00000204397,ENSG00000108179,ENSG00000111640,ENSG00000134352,ENSG00000167914,ENSG00000084092,ENSG00000116288,ENSG00000134765,ENSG00000180644,ENSG00000103202,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000023572,ENSG00000156463,ENSG00000143543,ENSG00000130402,ENSG00000071205,ENSG00000170312,ENSG00000164830,ENSG00000141576,ENSG00000070018,ENSG00000165949,ENSG00000055332,ENSG00000169230,ENSG00000153094,ENSG00000065135,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000152256,ENSG00000204472,ENSG00000089685,ENSG00000044574,ENSG00000007968,ENSG00000163545,ENSG00000166598,ENSG00000110448,ENSG00000129675,ENSG00000118971,ENSG00000196954,ENSG00000185650,ENSG00000100605,ENSG00000074800,ENSG00000105220,ENSG00000158869,ENSG00000145649,ENSG00000136717,ENSG00000071994,ENSG00000158006,ENSG00000100385,ENSG00000184916,ENSG00000067560,ENSG00000127952,ENSG00000189283,ENSG00000165304,ENSG00000185507,ENSG00000006625,ENSG00000168961,ENSG00000131747,ENSG00000132792,ENSG00000103495,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000112996,ENSG00000171169,ENSG00000178719,ENSG00000197043,ENSG00000096968,ENSG00000176641,ENSG00000165527,ENSG00000105612,ENSG00000168329,ENSG00000127666,ENSG00000196072,ENSG00000055163,ENSG00000185880,ENSG00000123338,ENSG00000128272,ENSG00000134049,ENSG00000142867,ENSG00000114126,ENSG00000126432,ENSG00000124155,ENSG00000172531,ENSG00000254087,ENSG00000160255,ENSG00000177076,ENSG00000172667,ENSG00000198851,ENSG00000196839,ENSG00000135960,ENSG00000028137,ENSG00000147889,ENSG00000137193,ENSG00000175104,ENSG00000078124,ENSG00000127084 |
| GO:0007155 | cell adhesion | 0.0000007 | 1440 | 712 | 102 | 0.1432584 | 0.0708333 | GO:BP | ENSG00000179344,ENSG00000117281,ENSG00000196126,ENSG00000248905,ENSG00000072110,ENSG00000073861,ENSG00000156886,ENSG00000163599,ENSG00000125347,ENSG00000108679,ENSG00000179218,ENSG00000159674,ENSG00000135077,ENSG00000147459,ENSG00000080573,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000173482,ENSG00000091129,ENSG00000221866,ENSG00000205336,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000196924,ENSG00000118193,ENSG00000150093,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000179051,ENSG00000112139,ENSG00000232810,ENSG00000117228,ENSG00000134352,ENSG00000139626,ENSG00000005844,ENSG00000167123,ENSG00000134765,ENSG00000073008,ENSG00000169855,ENSG00000130402,ENSG00000163359,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000153094,ENSG00000213445,ENSG00000163520,ENSG00000148400,ENSG00000204472,ENSG00000163823,ENSG00000147065,ENSG00000110448,ENSG00000111348,ENSG00000156234,ENSG00000185650,ENSG00000181467,ENSG00000168421,ENSG00000013725,ENSG00000184916,ENSG00000067560,ENSG00000213719,ENSG00000075340,ENSG00000133026,ENSG00000149294,ENSG00000168961,ENSG00000122122,ENSG00000172270,ENSG00000173517,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000111863,ENSG00000153310,ENSG00000070831,ENSG00000079691,ENSG00000075624,ENSG00000096968,ENSG00000165527,ENSG00000117155,ENSG00000168329,ENSG00000026751,ENSG00000116670,ENSG00000055163,ENSG00000123338,ENSG00000142867,ENSG00000172531,ENSG00000254087,ENSG00000160255,ENSG00000177076,ENSG00000127951,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000147889,ENSG00000140575,ENSG00000175104,ENSG00000114631,ENSG00000111859 |
| GO:0050792 | regulation of viral process | 0.0000007 | 212 | 712 | 29 | 0.0407303 | 0.1367925 | GO:BP | ENSG00000019582,ENSG00000115415,ENSG00000142089,ENSG00000172757,ENSG00000138795,ENSG00000232810,ENSG00000185201,ENSG00000135114,ENSG00000134321,ENSG00000185885,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000152778,ENSG00000185745,ENSG00000111331,ENSG00000100298,ENSG00000168961,ENSG00000148175,ENSG00000131747,ENSG00000187608,ENSG00000128394,ENSG00000111335,ENSG00000178685,ENSG00000132256,ENSG00000166794 |
| GO:0008219 | cell death | 0.0000008 | 2285 | 712 | 144 | 0.2022472 | 0.0630197 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000119922,ENSG00000100450,ENSG00000113721,ENSG00000117281,ENSG00000072110,ENSG00000073605,ENSG00000163599,ENSG00000132530,ENSG00000125347,ENSG00000179218,ENSG00000126709,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000144354,ENSG00000115415,ENSG00000119917,ENSG00000164111,ENSG00000101057,ENSG00000170315,ENSG00000156970,ENSG00000105639,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000146674,ENSG00000118193,ENSG00000120057,ENSG00000117984,ENSG00000150093,ENSG00000173848,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000183691,ENSG00000134308,ENSG00000204397,ENSG00000108179,ENSG00000111640,ENSG00000134352,ENSG00000167914,ENSG00000084092,ENSG00000116288,ENSG00000134765,ENSG00000180644,ENSG00000103202,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000023572,ENSG00000156463,ENSG00000143543,ENSG00000187446,ENSG00000130402,ENSG00000071205,ENSG00000170312,ENSG00000164830,ENSG00000141576,ENSG00000070018,ENSG00000165949,ENSG00000055332,ENSG00000169230,ENSG00000153094,ENSG00000065135,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000152256,ENSG00000204472,ENSG00000089685,ENSG00000044574,ENSG00000007968,ENSG00000163545,ENSG00000166598,ENSG00000110448,ENSG00000129675,ENSG00000118971,ENSG00000196954,ENSG00000185650,ENSG00000100605,ENSG00000074800,ENSG00000105220,ENSG00000158869,ENSG00000145649,ENSG00000136717,ENSG00000071994,ENSG00000158006,ENSG00000100385,ENSG00000184916,ENSG00000011485,ENSG00000067560,ENSG00000127952,ENSG00000189283,ENSG00000165304,ENSG00000185507,ENSG00000204642,ENSG00000006625,ENSG00000168961,ENSG00000131747,ENSG00000132792,ENSG00000103495,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000112996,ENSG00000171169,ENSG00000178719,ENSG00000197043,ENSG00000096968,ENSG00000176641,ENSG00000165527,ENSG00000105612,ENSG00000168329,ENSG00000127666,ENSG00000196072,ENSG00000138617,ENSG00000055163,ENSG00000185880,ENSG00000132386,ENSG00000123338,ENSG00000128272,ENSG00000134049,ENSG00000142867,ENSG00000114126,ENSG00000126432,ENSG00000124155,ENSG00000172531,ENSG00000254087,ENSG00000160255,ENSG00000177076,ENSG00000172667,ENSG00000198851,ENSG00000196839,ENSG00000135960,ENSG00000028137,ENSG00000147889,ENSG00000137193,ENSG00000175104,ENSG00000078124,ENSG00000127084,ENSG00000170485 |
| GO:0022610 | biological adhesion | 0.0000008 | 1447 | 712 | 102 | 0.1432584 | 0.0704907 | GO:BP | ENSG00000179344,ENSG00000117281,ENSG00000196126,ENSG00000248905,ENSG00000072110,ENSG00000073861,ENSG00000156886,ENSG00000163599,ENSG00000125347,ENSG00000108679,ENSG00000179218,ENSG00000159674,ENSG00000135077,ENSG00000147459,ENSG00000080573,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000173482,ENSG00000091129,ENSG00000221866,ENSG00000205336,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000196924,ENSG00000118193,ENSG00000150093,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000179051,ENSG00000112139,ENSG00000232810,ENSG00000117228,ENSG00000134352,ENSG00000139626,ENSG00000005844,ENSG00000167123,ENSG00000134765,ENSG00000073008,ENSG00000169855,ENSG00000130402,ENSG00000163359,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000153094,ENSG00000213445,ENSG00000163520,ENSG00000148400,ENSG00000204472,ENSG00000163823,ENSG00000147065,ENSG00000110448,ENSG00000111348,ENSG00000156234,ENSG00000185650,ENSG00000181467,ENSG00000168421,ENSG00000013725,ENSG00000184916,ENSG00000067560,ENSG00000213719,ENSG00000075340,ENSG00000133026,ENSG00000149294,ENSG00000168961,ENSG00000122122,ENSG00000172270,ENSG00000173517,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000111863,ENSG00000153310,ENSG00000070831,ENSG00000079691,ENSG00000075624,ENSG00000096968,ENSG00000165527,ENSG00000117155,ENSG00000168329,ENSG00000026751,ENSG00000116670,ENSG00000055163,ENSG00000123338,ENSG00000142867,ENSG00000172531,ENSG00000254087,ENSG00000160255,ENSG00000177076,ENSG00000127951,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000147889,ENSG00000140575,ENSG00000175104,ENSG00000114631,ENSG00000111859 |
| GO:0002443 | leukocyte mediated immunity | 0.0000011 | 880 | 712 | 71 | 0.0997191 | 0.0806818 | GO:BP | ENSG00000172057,ENSG00000100453,ENSG00000179344,ENSG00000117281,ENSG00000196126,ENSG00000073861,ENSG00000100321,ENSG00000159674,ENSG00000135077,ENSG00000089692,ENSG00000019582,ENSG00000105639,ENSG00000117984,ENSG00000186470,ENSG00000096996,ENSG00000189430,ENSG00000232810,ENSG00000134539,ENSG00000153563,ENSG00000005844,ENSG00000196230,ENSG00000134765,ENSG00000180644,ENSG00000073008,ENSG00000134321,ENSG00000137563,ENSG00000213281,ENSG00000123131,ENSG00000064666,ENSG00000072958,ENSG00000166710,ENSG00000138071,ENSG00000131236,ENSG00000021355,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000100299,ENSG00000163131,ENSG00000131504,ENSG00000067560,ENSG00000172794,ENSG00000185507,ENSG00000204642,ENSG00000168961,ENSG00000122122,ENSG00000148175,ENSG00000204592,ENSG00000174371,ENSG00000153310,ENSG00000172936,ENSG00000171302,ENSG00000147234,ENSG00000127666,ENSG00000139370,ENSG00000223496,ENSG00000026751,ENSG00000116670,ENSG00000123338,ENSG00000142867,ENSG00000140284,ENSG00000254087,ENSG00000160255,ENSG00000140319,ENSG00000127951,ENSG00000101082,ENSG00000131019,ENSG00000148218,ENSG00000028137,ENSG00000140575,ENSG00000175104 |
| GO:0051249 | regulation of lymphocyte activation | 0.0000011 | 509 | 712 | 49 | 0.0688202 | 0.0962672 | GO:BP | ENSG00000004468,ENSG00000179344,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000137265,ENSG00000096996,ENSG00000111537,ENSG00000134352,ENSG00000169230,ENSG00000204472,ENSG00000110448,ENSG00000185650,ENSG00000168421,ENSG00000013725,ENSG00000067560,ENSG00000204642,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000153310,ENSG00000070831,ENSG00000172936,ENSG00000127666,ENSG00000223496,ENSG00000116670,ENSG00000123338,ENSG00000142867,ENSG00000254087,ENSG00000127951,ENSG00000101082,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000028137,ENSG00000147889,ENSG00000175104 |
| GO:0019882 | antigen processing and presentation | 0.0000012 | 231 | 712 | 30 | 0.0421348 | 0.1298701 | GO:BP | ENSG00000164308,ENSG00000179344,ENSG00000204267,ENSG00000196126,ENSG00000092010,ENSG00000179218,ENSG00000089692,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000167004,ENSG00000117984,ENSG00000138160,ENSG00000153563,ENSG00000204264,ENSG00000072958,ENSG00000166710,ENSG00000158869,ENSG00000163131,ENSG00000204642,ENSG00000204592,ENSG00000042753,ENSG00000127022,ENSG00000041357,ENSG00000127951,ENSG00000242574,ENSG00000175104 |
| GO:0002699 | positive regulation of immune effector process | 0.0000015 | 207 | 712 | 28 | 0.0393258 | 0.1352657 | GO:BP | ENSG00000117281,ENSG00000073861,ENSG00000159674,ENSG00000089692,ENSG00000019582,ENSG00000096996,ENSG00000111537,ENSG00000232810,ENSG00000073008,ENSG00000134321,ENSG00000122223,ENSG00000166710,ENSG00000105220,ENSG00000158869,ENSG00000204642,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000157873,ENSG00000153310,ENSG00000127666,ENSG00000223496,ENSG00000116670,ENSG00000142867,ENSG00000254087,ENSG00000160255,ENSG00000242574,ENSG00000175104 |
| GO:0030217 | T cell differentiation | 0.0000015 | 247 | 712 | 31 | 0.0435393 | 0.1255061 | GO:BP | ENSG00000176083,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000105639,ENSG00000160654,ENSG00000137265,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000153563,ENSG00000134321,ENSG00000169230,ENSG00000166710,ENSG00000185650,ENSG00000158869,ENSG00000168421,ENSG00000184916,ENSG00000067560,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000167286,ENSG00000123338,ENSG00000127951,ENSG00000198851,ENSG00000196839,ENSG00000147889 |
| GO:0002694 | regulation of leukocyte activation | 0.0000016 | 598 | 712 | 54 | 0.0758427 | 0.0903010 | GO:BP | ENSG00000004468,ENSG00000179344,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000130164,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000137265,ENSG00000096996,ENSG00000111537,ENSG00000134352,ENSG00000077984,ENSG00000169230,ENSG00000204472,ENSG00000110448,ENSG00000185650,ENSG00000158869,ENSG00000168421,ENSG00000013725,ENSG00000067560,ENSG00000197417,ENSG00000204642,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000153310,ENSG00000070831,ENSG00000172936,ENSG00000127666,ENSG00000223496,ENSG00000116670,ENSG00000123338,ENSG00000142867,ENSG00000254087,ENSG00000160255,ENSG00000127951,ENSG00000101082,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000028137,ENSG00000147889,ENSG00000175104 |
| GO:1903047 | mitotic cell cycle process | 0.0000017 | 892 | 712 | 71 | 0.0997191 | 0.0795964 | GO:BP | ENSG00000148773,ENSG00000113721,ENSG00000092010,ENSG00000117724,ENSG00000165891,ENSG00000155657,ENSG00000160014,ENSG00000100911,ENSG00000101057,ENSG00000156970,ENSG00000171848,ENSG00000117632,ENSG00000196924,ENSG00000118193,ENSG00000112029,ENSG00000150093,ENSG00000138160,ENSG00000165617,ENSG00000111206,ENSG00000172757,ENSG00000179051,ENSG00000138180,ENSG00000126787,ENSG00000176890,ENSG00000100749,ENSG00000132646,ENSG00000103769,ENSG00000196230,ENSG00000175793,ENSG00000143543,ENSG00000204264,ENSG00000011426,ENSG00000170312,ENSG00000092853,ENSG00000061337,ENSG00000204472,ENSG00000089685,ENSG00000204899,ENSG00000118971,ENSG00000093009,ENSG00000185650,ENSG00000143476,ENSG00000122952,ENSG00000143228,ENSG00000053254,ENSG00000067560,ENSG00000165304,ENSG00000133026,ENSG00000113810,ENSG00000131747,ENSG00000139579,ENSG00000162676,ENSG00000106462,ENSG00000178996,ENSG00000176101,ENSG00000070831,ENSG00000152253,ENSG00000136824,ENSG00000109805,ENSG00000121579,ENSG00000116670,ENSG00000072571,ENSG00000124688,ENSG00000114126,ENSG00000104738,ENSG00000153044,ENSG00000041357,ENSG00000125354,ENSG00000136104,ENSG00000134690,ENSG00000147889 |
| GO:0002819 | regulation of adaptive immune response | 0.0000018 | 159 | 712 | 24 | 0.0337079 | 0.1509434 | GO:BP | ENSG00000179344,ENSG00000117281,ENSG00000073861,ENSG00000125347,ENSG00000135077,ENSG00000105639,ENSG00000096996,ENSG00000232810,ENSG00000134352,ENSG00000073008,ENSG00000134321,ENSG00000166710,ENSG00000158869,ENSG00000185507,ENSG00000204642,ENSG00000122122,ENSG00000204592,ENSG00000157873,ENSG00000153310,ENSG00000223496,ENSG00000116670,ENSG00000196839,ENSG00000028137,ENSG00000175104 |
| GO:0050865 | regulation of cell activation | 0.0000027 | 641 | 712 | 56 | 0.0786517 | 0.0873635 | GO:BP | ENSG00000004468,ENSG00000179344,ENSG00000113721,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000130164,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000137265,ENSG00000096996,ENSG00000111537,ENSG00000134352,ENSG00000077984,ENSG00000169230,ENSG00000204472,ENSG00000110448,ENSG00000185650,ENSG00000158869,ENSG00000168421,ENSG00000013725,ENSG00000067560,ENSG00000197417,ENSG00000204642,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000153310,ENSG00000070831,ENSG00000172936,ENSG00000096968,ENSG00000127666,ENSG00000223496,ENSG00000116670,ENSG00000123338,ENSG00000142867,ENSG00000254087,ENSG00000160255,ENSG00000127951,ENSG00000101082,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000028137,ENSG00000147889,ENSG00000175104 |
| GO:0046634 | regulation of alpha-beta T cell activation | 0.0000029 | 95 | 712 | 18 | 0.0252809 | 0.1894737 | GO:BP | ENSG00000179344,ENSG00000176083,ENSG00000117281,ENSG00000073861,ENSG00000125347,ENSG00000159216,ENSG00000105639,ENSG00000137265,ENSG00000096996,ENSG00000111537,ENSG00000067560,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000157873,ENSG00000123338,ENSG00000198851,ENSG00000196839 |
| GO:0002718 | regulation of cytokine production involved in immune response | 0.0000036 | 86 | 712 | 17 | 0.0238764 | 0.1976744 | GO:BP | ENSG00000117281,ENSG00000073861,ENSG00000159674,ENSG00000019582,ENSG00000105639,ENSG00000232810,ENSG00000134321,ENSG00000166710,ENSG00000158869,ENSG00000204642,ENSG00000122122,ENSG00000204592,ENSG00000157873,ENSG00000127666,ENSG00000142867,ENSG00000028137,ENSG00000175104 |
| GO:0002831 | regulation of response to biotic stimulus | 0.0000037 | 515 | 712 | 48 | 0.0674157 | 0.0932039 | GO:BP | ENSG00000138496,ENSG00000117281,ENSG00000092010,ENSG00000125347,ENSG00000135077,ENSG00000154451,ENSG00000163840,ENSG00000089692,ENSG00000115415,ENSG00000155629,ENSG00000100911,ENSG00000170315,ENSG00000137265,ENSG00000123609,ENSG00000096996,ENSG00000111537,ENSG00000189430,ENSG00000204397,ENSG00000073008,ENSG00000134321,ENSG00000204264,ENSG00000239713,ENSG00000213281,ENSG00000116030,ENSG00000185745,ENSG00000166598,ENSG00000158869,ENSG00000163131,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000204592,ENSG00000162676,ENSG00000172936,ENSG00000096968,ENSG00000164164,ENSG00000128394,ENSG00000127666,ENSG00000142867,ENSG00000138646,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000127951,ENSG00000137312,ENSG00000132256,ENSG00000175104 |
| GO:0050896 | response to stimulus | 0.0000037 | 9455 | 712 | 446 | 0.6264045 | 0.0471708 | GO:BP | ENSG00000172057,ENSG00000100453,ENSG00000004468,ENSG00000164308,ENSG00000179344,ENSG00000156587,ENSG00000119922,ENSG00000100450,ENSG00000138496,ENSG00000204267,ENSG00000113721,ENSG00000176083,ENSG00000211805,ENSG00000117281,ENSG00000196126,ENSG00000198826,ENSG00000092010,ENSG00000073605,ENSG00000073861,ENSG00000156886,ENSG00000163599,ENSG00000132530,ENSG00000117724,ENSG00000125347,ENSG00000108679,ENSG00000100321,ENSG00000180739,ENSG00000109956,ENSG00000179218,ENSG00000115523,ENSG00000211815,ENSG00000002834,ENSG00000126709,ENSG00000159674,ENSG00000135077,ENSG00000092068,ENSG00000160932,ENSG00000165891,ENSG00000147459,ENSG00000154451,ENSG00000162654,ENSG00000100427,ENSG00000134184,ENSG00000155657,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000163421,ENSG00000231925,ENSG00000019582,ENSG00000117560,ENSG00000072135,ENSG00000203747,ENSG00000159216,ENSG00000151502,ENSG00000160014,ENSG00000173482,ENSG00000130164,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000155629,ENSG00000186469,ENSG00000069702,ENSG00000091129,ENSG00000100911,ENSG00000221866,ENSG00000205336,ENSG00000164111,ENSG00000113368,ENSG00000101057,ENSG00000177156,ENSG00000163029,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000166503,ENSG00000213512,ENSG00000105639,ENSG00000117632,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000118193,ENSG00000112029,ENSG00000120057,ENSG00000117984,ENSG00000127947,ENSG00000186470,ENSG00000150093,ENSG00000136167,ENSG00000211746,ENSG00000167461,ENSG00000105409,ENSG00000123609,ENSG00000173848,ENSG00000096996,ENSG00000165617,ENSG00000125249,ENSG00000211698,ENSG00000111206,ENSG00000172757,ENSG00000138795,ENSG00000211745,ENSG00000110090,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000189430,ENSG00000099194,ENSG00000232810,ENSG00000211786,ENSG00000183691,ENSG00000134539,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000126787,ENSG00000176890,ENSG00000211721,ENSG00000204397,ENSG00000100749,ENSG00000108179,ENSG00000111640,ENSG00000118777,ENSG00000183734,ENSG00000172292,ENSG00000134352,ENSG00000139626,ENSG00000167914,ENSG00000132646,ENSG00000153563,ENSG00000103769,ENSG00000100380,ENSG00000108518,ENSG00000128335,ENSG00000117226,ENSG00000128284,ENSG00000131171,ENSG00000189319,ENSG00000005844,ENSG00000130592,ENSG00000103148,ENSG00000211747,ENSG00000185201,ENSG00000116288,ENSG00000196230,ENSG00000134765,ENSG00000171596,ENSG00000180644,ENSG00000111602,ENSG00000073008,ENSG00000213390,ENSG00000135114,ENSG00000134321,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000103966,ENSG00000023572,ENSG00000100918,ENSG00000152465,ENSG00000156463,ENSG00000137563,ENSG00000138642,ENSG00000204264,ENSG00000051341,ENSG00000188191,ENSG00000077984,ENSG00000114978,ENSG00000237254,ENSG00000187446,ENSG00000130402,ENSG00000071205,ENSG00000170312,ENSG00000105887,ENSG00000167618,ENSG00000155846,ENSG00000122223,ENSG00000136436,ENSG00000185885,ENSG00000185651,ENSG00000164830,ENSG00000117394,ENSG00000172116,ENSG00000131944,ENSG00000070018,ENSG00000165949,ENSG00000092853,ENSG00000055332,ENSG00000239713,ENSG00000242372,ENSG00000169230,ENSG00000153094,ENSG00000123416,ENSG00000065135,ENSG00000213445,ENSG00000104687,ENSG00000213281,ENSG00000123131,ENSG00000159200,ENSG00000148400,ENSG00000157601,ENSG00000041353,ENSG00000089127,ENSG00000167723,ENSG00000152256,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000163041,ENSG00000044574,ENSG00000133315,ENSG00000171246,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000072958,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000073803,ENSG00000159618,ENSG00000104805,ENSG00000163545,ENSG00000152778,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000166974,ENSG00000166454,ENSG00000180667,ENSG00000129422,ENSG00000166197,ENSG00000154001,ENSG00000126016,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000129007,ENSG00000131236,ENSG00000110448,ENSG00000111348,ENSG00000137959,ENSG00000148730,ENSG00000100342,ENSG00000156234,ENSG00000129675,ENSG00000021355,ENSG00000196954,ENSG00000183475,ENSG00000093009,ENSG00000101444,ENSG00000185650,ENSG00000100605,ENSG00000125871,ENSG00000111331,ENSG00000074800,ENSG00000143476,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000053254,ENSG00000145649,ENSG00000116983,ENSG00000168421,ENSG00000100299,ENSG00000013725,ENSG00000134909,ENSG00000158006,ENSG00000163131,ENSG00000170881,ENSG00000100385,ENSG00000125148,ENSG00000139921,ENSG00000131504,ENSG00000184916,ENSG00000198821,ENSG00000011485,ENSG00000067560,ENSG00000132932,ENSG00000197417,ENSG00000213928,ENSG00000127952,ENSG00000114166,ENSG00000189283,ENSG00000213719,ENSG00000165304,ENSG00000134202,ENSG00000172794,ENSG00000133026,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000204642,ENSG00000115267,ENSG00000006625,ENSG00000168961,ENSG00000115339,ENSG00000211794,ENSG00000122122,ENSG00000172270,ENSG00000122877,ENSG00000165283,ENSG00000148175,ENSG00000131747,ENSG00000141736,ENSG00000204592,ENSG00000132182,ENSG00000083444,ENSG00000103994,ENSG00000158321,ENSG00000174371,ENSG00000137965,ENSG00000213626,ENSG00000167286,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000139579,ENSG00000103495,ENSG00000162676,ENSG00000111863,ENSG00000106462,ENSG00000042753,ENSG00000153310,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000079691,ENSG00000172936,ENSG00000151239,ENSG00000101079,ENSG00000118705,ENSG00000179583,ENSG00000171302,ENSG00000178719,ENSG00000141030,ENSG00000147234,ENSG00000197043,ENSG00000054965,ENSG00000132670,ENSG00000066279,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000128394,ENSG00000075239,ENSG00000176641,ENSG00000109674,ENSG00000079999,ENSG00000170837,ENSG00000165527,ENSG00000117155,ENSG00000105612,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000139370,ENSG00000105697,ENSG00000223496,ENSG00000127022,ENSG00000197956,ENSG00000026751,ENSG00000148908,ENSG00000196072,ENSG00000138617,ENSG00000102931,ENSG00000125648,ENSG00000116670,ENSG00000055163,ENSG00000090520,ENSG00000132386,ENSG00000049239,ENSG00000256436,ENSG00000123338,ENSG00000128272,ENSG00000142867,ENSG00000110852,ENSG00000111335,ENSG00000114126,ENSG00000126432,ENSG00000198736,ENSG00000138646,ENSG00000049541,ENSG00000104738,ENSG00000119318,ENSG00000172531,ENSG00000168765,ENSG00000140284,ENSG00000137309,ENSG00000041357,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000143248,ENSG00000213366,ENSG00000140319,ENSG00000111796,ENSG00000177076,ENSG00000127951,ENSG00000155660,ENSG00000101082,ENSG00000131019,ENSG00000197409,ENSG00000172667,ENSG00000131873,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000143321,ENSG00000136104,ENSG00000155090,ENSG00000148218,ENSG00000242574,ENSG00000147168,ENSG00000177674,ENSG00000135960,ENSG00000028137,ENSG00000160753,ENSG00000178685,ENSG00000132256,ENSG00000147889,ENSG00000140575,ENSG00000137193,ENSG00000160404,ENSG00000111450,ENSG00000175104,ENSG00000078124,ENSG00000110218,ENSG00000169554,ENSG00000127084,ENSG00000113387,ENSG00000111859,ENSG00000170485,ENSG00000112759,ENSG00000081985 |
| GO:0050670 | regulation of lymphocyte proliferation | 0.0000045 | 219 | 712 | 28 | 0.0393258 | 0.1278539 | GO:BP | ENSG00000004468,ENSG00000196126,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000096996,ENSG00000134352,ENSG00000204472,ENSG00000013725,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000172936,ENSG00000127666,ENSG00000123338,ENSG00000254087,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000028137,ENSG00000147889,ENSG00000175104 |
| GO:0030097 | hemopoiesis | 0.0000045 | 916 | 712 | 71 | 0.0997191 | 0.0775109 | GO:BP | ENSG00000179344,ENSG00000113721,ENSG00000176083,ENSG00000092010,ENSG00000072110,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000115415,ENSG00000069702,ENSG00000100911,ENSG00000105639,ENSG00000160654,ENSG00000137265,ENSG00000157216,ENSG00000150093,ENSG00000096996,ENSG00000172331,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000153563,ENSG00000134321,ENSG00000138642,ENSG00000204264,ENSG00000011426,ENSG00000160219,ENSG00000155846,ENSG00000055332,ENSG00000242372,ENSG00000169230,ENSG00000148400,ENSG00000163041,ENSG00000064666,ENSG00000166710,ENSG00000163823,ENSG00000185650,ENSG00000158869,ENSG00000071994,ENSG00000168421,ENSG00000184916,ENSG00000067560,ENSG00000114166,ENSG00000165304,ENSG00000075340,ENSG00000185507,ENSG00000168961,ENSG00000122122,ENSG00000131747,ENSG00000141736,ENSG00000167286,ENSG00000187608,ENSG00000162676,ENSG00000070831,ENSG00000096968,ENSG00000105612,ENSG00000123338,ENSG00000041357,ENSG00000254087,ENSG00000091127,ENSG00000127951,ENSG00000197409,ENSG00000198851,ENSG00000196839,ENSG00000155090,ENSG00000147889,ENSG00000137193,ENSG00000175104 |
| GO:1903706 | regulation of hemopoiesis | 0.0000051 | 489 | 712 | 46 | 0.0646067 | 0.0940695 | GO:BP | ENSG00000176083,ENSG00000092010,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000115415,ENSG00000100911,ENSG00000105639,ENSG00000137265,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000204264,ENSG00000155846,ENSG00000055332,ENSG00000242372,ENSG00000169230,ENSG00000148400,ENSG00000163041,ENSG00000166710,ENSG00000163823,ENSG00000185650,ENSG00000071994,ENSG00000168421,ENSG00000067560,ENSG00000114166,ENSG00000185507,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000187608,ENSG00000123338,ENSG00000041357,ENSG00000254087,ENSG00000091127,ENSG00000127951,ENSG00000197409,ENSG00000196839,ENSG00000155090,ENSG00000147889,ENSG00000137193,ENSG00000175104 |
| GO:0032944 | regulation of mononuclear cell proliferation | 0.0000052 | 221 | 712 | 28 | 0.0393258 | 0.1266968 | GO:BP | ENSG00000004468,ENSG00000196126,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000096996,ENSG00000134352,ENSG00000204472,ENSG00000013725,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000172936,ENSG00000127666,ENSG00000123338,ENSG00000254087,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000028137,ENSG00000147889,ENSG00000175104 |
| GO:0002702 | positive regulation of production of molecular mediator of immune response | 0.0000052 | 99 | 712 | 18 | 0.0252809 | 0.1818182 | GO:BP | ENSG00000117281,ENSG00000073861,ENSG00000159674,ENSG00000019582,ENSG00000134321,ENSG00000122223,ENSG00000166710,ENSG00000105220,ENSG00000158869,ENSG00000204642,ENSG00000122122,ENSG00000204592,ENSG00000157873,ENSG00000127666,ENSG00000223496,ENSG00000116670,ENSG00000142867,ENSG00000175104 |
| GO:0050867 | positive regulation of cell activation | 0.0000053 | 411 | 712 | 41 | 0.0575843 | 0.0997567 | GO:BP | ENSG00000004468,ENSG00000179344,ENSG00000113721,ENSG00000117281,ENSG00000073861,ENSG00000163599,ENSG00000135077,ENSG00000019582,ENSG00000159216,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000096996,ENSG00000111537,ENSG00000134352,ENSG00000204472,ENSG00000110448,ENSG00000158869,ENSG00000168421,ENSG00000013725,ENSG00000067560,ENSG00000204642,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000157873,ENSG00000153310,ENSG00000070831,ENSG00000172936,ENSG00000096968,ENSG00000127666,ENSG00000223496,ENSG00000116670,ENSG00000123338,ENSG00000142867,ENSG00000254087,ENSG00000160255,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000175104 |
| GO:0051251 | positive regulation of lymphocyte activation | 0.0000057 | 351 | 712 | 37 | 0.0519663 | 0.1054131 | GO:BP | ENSG00000004468,ENSG00000179344,ENSG00000117281,ENSG00000073861,ENSG00000163599,ENSG00000135077,ENSG00000019582,ENSG00000159216,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000096996,ENSG00000111537,ENSG00000134352,ENSG00000204472,ENSG00000110448,ENSG00000168421,ENSG00000013725,ENSG00000067560,ENSG00000204642,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000157873,ENSG00000153310,ENSG00000070831,ENSG00000172936,ENSG00000127666,ENSG00000223496,ENSG00000116670,ENSG00000123338,ENSG00000142867,ENSG00000254087,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000175104 |
| GO:0002449 | lymphocyte mediated immunity | 0.0000101 | 359 | 712 | 37 | 0.0519663 | 0.1030641 | GO:BP | ENSG00000100453,ENSG00000179344,ENSG00000117281,ENSG00000196126,ENSG00000073861,ENSG00000135077,ENSG00000089692,ENSG00000019582,ENSG00000186470,ENSG00000096996,ENSG00000189430,ENSG00000232810,ENSG00000134539,ENSG00000153563,ENSG00000196230,ENSG00000180644,ENSG00000073008,ENSG00000134321,ENSG00000166710,ENSG00000158869,ENSG00000185507,ENSG00000204642,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000174371,ENSG00000153310,ENSG00000172936,ENSG00000223496,ENSG00000026751,ENSG00000116670,ENSG00000142867,ENSG00000127951,ENSG00000101082,ENSG00000131019,ENSG00000028137,ENSG00000175104 |
| GO:0048534 | hematopoietic or lymphoid organ development | 0.0000103 | 956 | 712 | 72 | 0.1011236 | 0.0753138 | GO:BP | ENSG00000179344,ENSG00000113721,ENSG00000176083,ENSG00000092010,ENSG00000072110,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000115415,ENSG00000069702,ENSG00000100911,ENSG00000105639,ENSG00000160654,ENSG00000137265,ENSG00000157216,ENSG00000150093,ENSG00000096996,ENSG00000172331,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000153563,ENSG00000134321,ENSG00000138642,ENSG00000204264,ENSG00000011426,ENSG00000160219,ENSG00000155846,ENSG00000055332,ENSG00000242372,ENSG00000169230,ENSG00000153094,ENSG00000148400,ENSG00000163041,ENSG00000064666,ENSG00000166710,ENSG00000163823,ENSG00000185650,ENSG00000158869,ENSG00000071994,ENSG00000168421,ENSG00000184916,ENSG00000067560,ENSG00000114166,ENSG00000165304,ENSG00000075340,ENSG00000185507,ENSG00000168961,ENSG00000122122,ENSG00000131747,ENSG00000141736,ENSG00000167286,ENSG00000187608,ENSG00000162676,ENSG00000070831,ENSG00000096968,ENSG00000105612,ENSG00000123338,ENSG00000041357,ENSG00000254087,ENSG00000091127,ENSG00000127951,ENSG00000197409,ENSG00000198851,ENSG00000196839,ENSG00000155090,ENSG00000147889,ENSG00000137193,ENSG00000175104 |
| GO:0001817 | regulation of cytokine production | 0.0000137 | 764 | 712 | 61 | 0.0856742 | 0.0798429 | GO:BP | ENSG00000156587,ENSG00000117281,ENSG00000196126,ENSG00000073861,ENSG00000125347,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000115415,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000137265,ENSG00000186470,ENSG00000123609,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000204397,ENSG00000111640,ENSG00000134352,ENSG00000116288,ENSG00000134321,ENSG00000122223,ENSG00000055332,ENSG00000204472,ENSG00000166710,ENSG00000241258,ENSG00000021355,ENSG00000158869,ENSG00000013725,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000187608,ENSG00000157873,ENSG00000153310,ENSG00000172936,ENSG00000096968,ENSG00000168329,ENSG00000127666,ENSG00000123338,ENSG00000128272,ENSG00000142867,ENSG00000138646,ENSG00000254087,ENSG00000137312,ENSG00000198851,ENSG00000028137,ENSG00000140575,ENSG00000175104,ENSG00000110218,ENSG00000081985 |
| GO:0001816 | cytokine production | 0.0000144 | 837 | 712 | 65 | 0.0912921 | 0.0776583 | GO:BP | ENSG00000156587,ENSG00000117281,ENSG00000196126,ENSG00000073861,ENSG00000125347,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000115415,ENSG00000205336,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000137265,ENSG00000186470,ENSG00000123609,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000204397,ENSG00000111640,ENSG00000134352,ENSG00000116288,ENSG00000134321,ENSG00000122223,ENSG00000055332,ENSG00000148400,ENSG00000204472,ENSG00000166710,ENSG00000241258,ENSG00000021355,ENSG00000158869,ENSG00000013725,ENSG00000198821,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000122122,ENSG00000165283,ENSG00000204592,ENSG00000187608,ENSG00000157873,ENSG00000153310,ENSG00000172936,ENSG00000096968,ENSG00000168329,ENSG00000127666,ENSG00000123338,ENSG00000128272,ENSG00000142867,ENSG00000138646,ENSG00000254087,ENSG00000137312,ENSG00000198851,ENSG00000028137,ENSG00000140575,ENSG00000175104,ENSG00000110218,ENSG00000081985 |
| GO:0002696 | positive regulation of leukocyte activation | 0.0000147 | 396 | 712 | 39 | 0.0547753 | 0.0984848 | GO:BP | ENSG00000004468,ENSG00000179344,ENSG00000117281,ENSG00000073861,ENSG00000163599,ENSG00000135077,ENSG00000019582,ENSG00000159216,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000096996,ENSG00000111537,ENSG00000134352,ENSG00000204472,ENSG00000110448,ENSG00000158869,ENSG00000168421,ENSG00000013725,ENSG00000067560,ENSG00000204642,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000157873,ENSG00000153310,ENSG00000070831,ENSG00000172936,ENSG00000127666,ENSG00000223496,ENSG00000116670,ENSG00000123338,ENSG00000142867,ENSG00000254087,ENSG00000160255,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000175104 |
| GO:0035722 | interleukin-12-mediated signaling pathway | 0.0000155 | 47 | 712 | 12 | 0.0168539 | 0.2553191 | GO:BP | ENSG00000100911,ENSG00000113368,ENSG00000177156,ENSG00000136167,ENSG00000096996,ENSG00000172757,ENSG00000111537,ENSG00000064666,ENSG00000147065,ENSG00000070831,ENSG00000096968,ENSG00000081985 |
| GO:0048522 | positive regulation of cellular process | 0.0000155 | 5605 | 712 | 286 | 0.4016854 | 0.0510259 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000179344,ENSG00000119922,ENSG00000138496,ENSG00000113721,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000248905,ENSG00000072110,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000179218,ENSG00000002834,ENSG00000184357,ENSG00000135077,ENSG00000165891,ENSG00000147459,ENSG00000154451,ENSG00000155657,ENSG00000163840,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000164649,ENSG00000159216,ENSG00000160014,ENSG00000130164,ENSG00000127124,ENSG00000115415,ENSG00000155629,ENSG00000069702,ENSG00000091129,ENSG00000100911,ENSG00000130511,ENSG00000221866,ENSG00000205336,ENSG00000164111,ENSG00000124191,ENSG00000101057,ENSG00000163029,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000125868,ENSG00000105639,ENSG00000117632,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000118193,ENSG00000112029,ENSG00000117984,ENSG00000157216,ENSG00000150093,ENSG00000136167,ENSG00000121039,ENSG00000123609,ENSG00000173848,ENSG00000096996,ENSG00000165617,ENSG00000125249,ENSG00000173114,ENSG00000111206,ENSG00000133321,ENSG00000172757,ENSG00000138795,ENSG00000110090,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000232810,ENSG00000183691,ENSG00000134308,ENSG00000126787,ENSG00000204397,ENSG00000108179,ENSG00000111640,ENSG00000183734,ENSG00000134352,ENSG00000132646,ENSG00000103769,ENSG00000108518,ENSG00000128284,ENSG00000131171,ENSG00000189319,ENSG00000116288,ENSG00000111602,ENSG00000134321,ENSG00000175793,ENSG00000169855,ENSG00000103966,ENSG00000124575,ENSG00000156463,ENSG00000143543,ENSG00000204264,ENSG00000196976,ENSG00000188191,ENSG00000077984,ENSG00000187446,ENSG00000130402,ENSG00000011426,ENSG00000170312,ENSG00000105887,ENSG00000155846,ENSG00000122223,ENSG00000136436,ENSG00000185885,ENSG00000185651,ENSG00000141576,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000125462,ENSG00000092853,ENSG00000055332,ENSG00000242372,ENSG00000169230,ENSG00000153094,ENSG00000065135,ENSG00000213281,ENSG00000148400,ENSG00000164211,ENSG00000041353,ENSG00000204472,ENSG00000089685,ENSG00000121297,ENSG00000163041,ENSG00000044574,ENSG00000188612,ENSG00000130741,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000118263,ENSG00000132274,ENSG00000166710,ENSG00000111229,ENSG00000073803,ENSG00000152778,ENSG00000163823,ENSG00000147065,ENSG00000166974,ENSG00000166454,ENSG00000166197,ENSG00000253626,ENSG00000138071,ENSG00000110448,ENSG00000156234,ENSG00000129675,ENSG00000118971,ENSG00000196954,ENSG00000093009,ENSG00000185650,ENSG00000074800,ENSG00000143476,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000171222,ENSG00000145649,ENSG00000136717,ENSG00000071994,ENSG00000168421,ENSG00000013725,ENSG00000170881,ENSG00000131504,ENSG00000184916,ENSG00000180574,ENSG00000011485,ENSG00000067560,ENSG00000132932,ENSG00000125944,ENSG00000127952,ENSG00000114166,ENSG00000213719,ENSG00000165304,ENSG00000133026,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000087302,ENSG00000168961,ENSG00000122122,ENSG00000122877,ENSG00000165283,ENSG00000131747,ENSG00000171617,ENSG00000141736,ENSG00000162702,ENSG00000204592,ENSG00000132792,ENSG00000158321,ENSG00000118564,ENSG00000160877,ENSG00000213626,ENSG00000167286,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000139579,ENSG00000103495,ENSG00000162676,ENSG00000111863,ENSG00000106462,ENSG00000153310,ENSG00000104765,ENSG00000070831,ENSG00000079691,ENSG00000172936,ENSG00000124920,ENSG00000151239,ENSG00000179583,ENSG00000171302,ENSG00000054965,ENSG00000066279,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000258289,ENSG00000176641,ENSG00000079999,ENSG00000170837,ENSG00000165527,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000105697,ENSG00000223496,ENSG00000197956,ENSG00000138617,ENSG00000184897,ENSG00000102931,ENSG00000116670,ENSG00000055163,ENSG00000184640,ENSG00000132386,ENSG00000123338,ENSG00000140450,ENSG00000171943,ENSG00000128272,ENSG00000148337,ENSG00000142867,ENSG00000114126,ENSG00000143740,ENSG00000049541,ENSG00000172531,ENSG00000178691,ENSG00000137309,ENSG00000041357,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000213366,ENSG00000177076,ENSG00000101082,ENSG00000172667,ENSG00000131873,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000136104,ENSG00000155090,ENSG00000242574,ENSG00000135960,ENSG00000028137,ENSG00000160753,ENSG00000132256,ENSG00000147889,ENSG00000140575,ENSG00000137193,ENSG00000175104,ENSG00000078124,ENSG00000110218,ENSG00000169554,ENSG00000127084,ENSG00000113387,ENSG00000111859,ENSG00000147180,ENSG00000170485,ENSG00000081985 |
| GO:0048518 | positive regulation of biological process | 0.0000155 | 6366 | 712 | 318 | 0.4466292 | 0.0499529 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000179344,ENSG00000119922,ENSG00000138496,ENSG00000113721,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000092010,ENSG00000248905,ENSG00000072110,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000179218,ENSG00000002834,ENSG00000159674,ENSG00000184357,ENSG00000135077,ENSG00000165891,ENSG00000147459,ENSG00000154451,ENSG00000100427,ENSG00000155657,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000164649,ENSG00000203747,ENSG00000159216,ENSG00000160014,ENSG00000130164,ENSG00000127124,ENSG00000115415,ENSG00000155629,ENSG00000069702,ENSG00000091129,ENSG00000100911,ENSG00000130511,ENSG00000221866,ENSG00000205336,ENSG00000164111,ENSG00000124191,ENSG00000101057,ENSG00000163029,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000125868,ENSG00000105639,ENSG00000117632,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000118193,ENSG00000112029,ENSG00000117984,ENSG00000186470,ENSG00000157216,ENSG00000150093,ENSG00000136167,ENSG00000121039,ENSG00000123609,ENSG00000173848,ENSG00000096996,ENSG00000165617,ENSG00000125249,ENSG00000173114,ENSG00000111206,ENSG00000133321,ENSG00000172757,ENSG00000138795,ENSG00000110090,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000099194,ENSG00000232810,ENSG00000183691,ENSG00000117228,ENSG00000134308,ENSG00000126787,ENSG00000204397,ENSG00000108179,ENSG00000111640,ENSG00000183734,ENSG00000134352,ENSG00000132646,ENSG00000103769,ENSG00000108518,ENSG00000128284,ENSG00000131171,ENSG00000189319,ENSG00000116288,ENSG00000180644,ENSG00000111602,ENSG00000073008,ENSG00000134321,ENSG00000175793,ENSG00000169855,ENSG00000103966,ENSG00000124575,ENSG00000156463,ENSG00000143543,ENSG00000204264,ENSG00000196976,ENSG00000188191,ENSG00000077984,ENSG00000187446,ENSG00000130402,ENSG00000011426,ENSG00000170312,ENSG00000105887,ENSG00000155846,ENSG00000122223,ENSG00000136436,ENSG00000185885,ENSG00000185651,ENSG00000141576,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000125462,ENSG00000092853,ENSG00000055332,ENSG00000242372,ENSG00000169230,ENSG00000153094,ENSG00000065135,ENSG00000213281,ENSG00000163520,ENSG00000148400,ENSG00000164211,ENSG00000041353,ENSG00000167723,ENSG00000204472,ENSG00000089685,ENSG00000121297,ENSG00000163041,ENSG00000044574,ENSG00000188612,ENSG00000130741,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000132274,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000073803,ENSG00000152778,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000166974,ENSG00000166454,ENSG00000166197,ENSG00000126016,ENSG00000241258,ENSG00000253626,ENSG00000138071,ENSG00000166598,ENSG00000110448,ENSG00000156234,ENSG00000129675,ENSG00000118971,ENSG00000196954,ENSG00000093009,ENSG00000185650,ENSG00000074800,ENSG00000143476,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000171222,ENSG00000145649,ENSG00000136717,ENSG00000071994,ENSG00000168421,ENSG00000013725,ENSG00000163131,ENSG00000170881,ENSG00000100385,ENSG00000131504,ENSG00000184916,ENSG00000180574,ENSG00000198821,ENSG00000011485,ENSG00000067560,ENSG00000132932,ENSG00000125944,ENSG00000127952,ENSG00000114166,ENSG00000213719,ENSG00000165304,ENSG00000133026,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000087302,ENSG00000168961,ENSG00000122122,ENSG00000122877,ENSG00000165283,ENSG00000148175,ENSG00000131747,ENSG00000171617,ENSG00000141736,ENSG00000162702,ENSG00000204592,ENSG00000132792,ENSG00000158321,ENSG00000118564,ENSG00000160877,ENSG00000213626,ENSG00000167286,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000139579,ENSG00000103495,ENSG00000162676,ENSG00000111863,ENSG00000106462,ENSG00000153310,ENSG00000104765,ENSG00000070831,ENSG00000079691,ENSG00000172936,ENSG00000124920,ENSG00000151239,ENSG00000164088,ENSG00000179583,ENSG00000171302,ENSG00000054965,ENSG00000066279,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000258289,ENSG00000176641,ENSG00000079999,ENSG00000170837,ENSG00000165527,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000105697,ENSG00000223496,ENSG00000197956,ENSG00000138617,ENSG00000184897,ENSG00000102931,ENSG00000116670,ENSG00000055163,ENSG00000184640,ENSG00000132386,ENSG00000123338,ENSG00000140450,ENSG00000171943,ENSG00000128272,ENSG00000148337,ENSG00000142867,ENSG00000114126,ENSG00000143740,ENSG00000145337,ENSG00000049541,ENSG00000172531,ENSG00000178691,ENSG00000129968,ENSG00000137309,ENSG00000041357,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000213366,ENSG00000177076,ENSG00000101082,ENSG00000172667,ENSG00000150756,ENSG00000131873,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000136104,ENSG00000155090,ENSG00000242574,ENSG00000147168,ENSG00000135960,ENSG00000028137,ENSG00000160753,ENSG00000169223,ENSG00000132256,ENSG00000147889,ENSG00000140575,ENSG00000137193,ENSG00000155096,ENSG00000175104,ENSG00000078124,ENSG00000110218,ENSG00000169554,ENSG00000127084,ENSG00000113387,ENSG00000166794,ENSG00000111859,ENSG00000147180,ENSG00000170485,ENSG00000081985 |
| GO:0070663 | regulation of leukocyte proliferation | 0.0000155 | 234 | 712 | 28 | 0.0393258 | 0.1196581 | GO:BP | ENSG00000004468,ENSG00000196126,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000096996,ENSG00000134352,ENSG00000204472,ENSG00000013725,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000172936,ENSG00000127666,ENSG00000123338,ENSG00000254087,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000028137,ENSG00000147889,ENSG00000175104 |
| GO:0046631 | alpha-beta T cell activation | 0.0000155 | 142 | 712 | 21 | 0.0294944 | 0.1478873 | GO:BP | ENSG00000179344,ENSG00000176083,ENSG00000117281,ENSG00000073861,ENSG00000125347,ENSG00000159216,ENSG00000105639,ENSG00000137265,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000134321,ENSG00000067560,ENSG00000168961,ENSG00000122122,ENSG00000165283,ENSG00000204592,ENSG00000157873,ENSG00000123338,ENSG00000198851,ENSG00000196839 |
| GO:0051301 | cell division | 0.0000158 | 612 | 712 | 52 | 0.0730337 | 0.0849673 | GO:BP | ENSG00000117724,ENSG00000165891,ENSG00000164649,ENSG00000160014,ENSG00000156970,ENSG00000117632,ENSG00000118193,ENSG00000112029,ENSG00000138160,ENSG00000172757,ENSG00000138795,ENSG00000179051,ENSG00000138180,ENSG00000133739,ENSG00000100749,ENSG00000103769,ENSG00000196230,ENSG00000111602,ENSG00000175793,ENSG00000143543,ENSG00000011426,ENSG00000170312,ENSG00000123416,ENSG00000065135,ENSG00000148400,ENSG00000089685,ENSG00000166974,ENSG00000138071,ENSG00000118971,ENSG00000129534,ENSG00000122952,ENSG00000143228,ENSG00000067560,ENSG00000133026,ENSG00000113810,ENSG00000131747,ENSG00000213626,ENSG00000178996,ENSG00000070831,ENSG00000152253,ENSG00000066279,ENSG00000136824,ENSG00000165527,ENSG00000109805,ENSG00000116670,ENSG00000184640,ENSG00000172531,ENSG00000125354,ENSG00000182628,ENSG00000134690,ENSG00000147889,ENSG00000111859 |
| GO:0002720 | positive regulation of cytokine production involved in immune response | 0.0000158 | 56 | 712 | 13 | 0.0182584 | 0.2321429 | GO:BP | ENSG00000117281,ENSG00000159674,ENSG00000019582,ENSG00000134321,ENSG00000166710,ENSG00000158869,ENSG00000204642,ENSG00000122122,ENSG00000204592,ENSG00000157873,ENSG00000127666,ENSG00000142867,ENSG00000175104 |
| GO:0000278 | mitotic cell cycle | 0.0000160 | 1082 | 712 | 78 | 0.1095506 | 0.0720887 | GO:BP | ENSG00000148773,ENSG00000113721,ENSG00000092010,ENSG00000117724,ENSG00000165891,ENSG00000155657,ENSG00000160014,ENSG00000100911,ENSG00000101057,ENSG00000156970,ENSG00000171848,ENSG00000117632,ENSG00000196924,ENSG00000118193,ENSG00000112029,ENSG00000150093,ENSG00000138160,ENSG00000165617,ENSG00000111206,ENSG00000172757,ENSG00000179051,ENSG00000232810,ENSG00000138180,ENSG00000126787,ENSG00000176890,ENSG00000100749,ENSG00000132646,ENSG00000103769,ENSG00000196230,ENSG00000175793,ENSG00000143543,ENSG00000204264,ENSG00000011426,ENSG00000170312,ENSG00000092853,ENSG00000061337,ENSG00000123416,ENSG00000204472,ENSG00000089685,ENSG00000204899,ENSG00000166197,ENSG00000131931,ENSG00000118971,ENSG00000093009,ENSG00000185650,ENSG00000143476,ENSG00000122952,ENSG00000143228,ENSG00000053254,ENSG00000011485,ENSG00000067560,ENSG00000165304,ENSG00000133026,ENSG00000113810,ENSG00000131747,ENSG00000139579,ENSG00000162676,ENSG00000106462,ENSG00000178996,ENSG00000176101,ENSG00000070831,ENSG00000152253,ENSG00000136824,ENSG00000109805,ENSG00000121579,ENSG00000116670,ENSG00000072571,ENSG00000124688,ENSG00000114126,ENSG00000104738,ENSG00000153044,ENSG00000041357,ENSG00000125354,ENSG00000182628,ENSG00000136104,ENSG00000134690,ENSG00000147889,ENSG00000140575 |
| GO:0051240 | positive regulation of multicellular organismal process | 0.0000172 | 1853 | 712 | 117 | 0.1643258 | 0.0631409 | GO:BP | ENSG00000004468,ENSG00000113721,ENSG00000117281,ENSG00000007402,ENSG00000073861,ENSG00000125347,ENSG00000179218,ENSG00000159674,ENSG00000135077,ENSG00000147459,ENSG00000154451,ENSG00000163421,ENSG00000019582,ENSG00000159216,ENSG00000115415,ENSG00000069702,ENSG00000091129,ENSG00000221866,ENSG00000223865,ENSG00000231389,ENSG00000169252,ENSG00000196924,ENSG00000137265,ENSG00000112029,ENSG00000150093,ENSG00000096996,ENSG00000173114,ENSG00000133321,ENSG00000138795,ENSG00000111537,ENSG00000099194,ENSG00000232810,ENSG00000183691,ENSG00000111640,ENSG00000134352,ENSG00000103769,ENSG00000108518,ENSG00000116288,ENSG00000134321,ENSG00000169855,ENSG00000077984,ENSG00000170312,ENSG00000105887,ENSG00000155846,ENSG00000122223,ENSG00000185885,ENSG00000141576,ENSG00000139182,ENSG00000171603,ENSG00000055332,ENSG00000148400,ENSG00000204472,ENSG00000044574,ENSG00000166710,ENSG00000073803,ENSG00000163823,ENSG00000166974,ENSG00000126016,ENSG00000241258,ENSG00000138071,ENSG00000185650,ENSG00000074800,ENSG00000105220,ENSG00000158869,ENSG00000136717,ENSG00000071994,ENSG00000168421,ENSG00000013725,ENSG00000067560,ENSG00000132932,ENSG00000127952,ENSG00000213719,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000122122,ENSG00000171617,ENSG00000204592,ENSG00000213626,ENSG00000187608,ENSG00000157873,ENSG00000106462,ENSG00000153310,ENSG00000070831,ENSG00000172936,ENSG00000124920,ENSG00000151239,ENSG00000066279,ENSG00000096968,ENSG00000165527,ENSG00000168329,ENSG00000127666,ENSG00000105697,ENSG00000223496,ENSG00000116670,ENSG00000132386,ENSG00000123338,ENSG00000171943,ENSG00000128272,ENSG00000142867,ENSG00000254087,ENSG00000160255,ENSG00000150756,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000155090,ENSG00000028137,ENSG00000140575,ENSG00000137193,ENSG00000175104,ENSG00000110218,ENSG00000169554,ENSG00000166794,ENSG00000170485,ENSG00000081985 |
| GO:0002697 | regulation of immune effector process | 0.0000205 | 451 | 712 | 42 | 0.0589888 | 0.0931264 | GO:BP | ENSG00000138496,ENSG00000176083,ENSG00000117281,ENSG00000073861,ENSG00000159674,ENSG00000135077,ENSG00000163840,ENSG00000089692,ENSG00000019582,ENSG00000115415,ENSG00000105639,ENSG00000137265,ENSG00000096996,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000073008,ENSG00000134321,ENSG00000122223,ENSG00000239713,ENSG00000166710,ENSG00000185745,ENSG00000105220,ENSG00000158869,ENSG00000204642,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000157873,ENSG00000153310,ENSG00000128394,ENSG00000127666,ENSG00000223496,ENSG00000116670,ENSG00000142867,ENSG00000138646,ENSG00000254087,ENSG00000160255,ENSG00000127951,ENSG00000242574,ENSG00000028137,ENSG00000175104 |
| GO:0002700 | regulation of production of molecular mediator of immune response | 0.0000205 | 145 | 712 | 21 | 0.0294944 | 0.1448276 | GO:BP | ENSG00000117281,ENSG00000073861,ENSG00000159674,ENSG00000019582,ENSG00000105639,ENSG00000232810,ENSG00000134321,ENSG00000122223,ENSG00000166710,ENSG00000105220,ENSG00000158869,ENSG00000204642,ENSG00000122122,ENSG00000204592,ENSG00000157873,ENSG00000127666,ENSG00000223496,ENSG00000116670,ENSG00000142867,ENSG00000028137,ENSG00000175104 |
| GO:0070665 | positive regulation of leukocyte proliferation | 0.0000205 | 145 | 712 | 21 | 0.0294944 | 0.1448276 | GO:BP | ENSG00000004468,ENSG00000135077,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000096996,ENSG00000134352,ENSG00000204472,ENSG00000013725,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000172936,ENSG00000127666,ENSG00000123338,ENSG00000254087,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000175104 |
| GO:0071349 | cellular response to interleukin-12 | 0.0000234 | 49 | 712 | 12 | 0.0168539 | 0.2448980 | GO:BP | ENSG00000100911,ENSG00000113368,ENSG00000177156,ENSG00000136167,ENSG00000096996,ENSG00000172757,ENSG00000111537,ENSG00000064666,ENSG00000147065,ENSG00000070831,ENSG00000096968,ENSG00000081985 |
| GO:0001819 | positive regulation of cytokine production | 0.0000236 | 470 | 712 | 43 | 0.0603933 | 0.0914894 | GO:BP | ENSG00000117281,ENSG00000125347,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000019582,ENSG00000159216,ENSG00000115415,ENSG00000223865,ENSG00000231389,ENSG00000137265,ENSG00000096996,ENSG00000111537,ENSG00000232810,ENSG00000111640,ENSG00000134352,ENSG00000116288,ENSG00000134321,ENSG00000122223,ENSG00000055332,ENSG00000204472,ENSG00000166710,ENSG00000241258,ENSG00000158869,ENSG00000013725,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000157873,ENSG00000153310,ENSG00000172936,ENSG00000096968,ENSG00000127666,ENSG00000128272,ENSG00000142867,ENSG00000137312,ENSG00000198851,ENSG00000175104,ENSG00000110218,ENSG00000081985 |
| GO:0045580 | regulation of T cell differentiation | 0.0000250 | 147 | 712 | 21 | 0.0294944 | 0.1428571 | GO:BP | ENSG00000176083,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000105639,ENSG00000137265,ENSG00000096996,ENSG00000111537,ENSG00000169230,ENSG00000168421,ENSG00000067560,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000123338,ENSG00000127951,ENSG00000196839,ENSG00000147889 |
| GO:0070671 | response to interleukin-12 | 0.0000288 | 50 | 712 | 12 | 0.0168539 | 0.2400000 | GO:BP | ENSG00000100911,ENSG00000113368,ENSG00000177156,ENSG00000136167,ENSG00000096996,ENSG00000172757,ENSG00000111537,ENSG00000064666,ENSG00000147065,ENSG00000070831,ENSG00000096968,ENSG00000081985 |
| GO:0050671 | positive regulation of lymphocyte proliferation | 0.0000288 | 136 | 712 | 20 | 0.0280899 | 0.1470588 | GO:BP | ENSG00000004468,ENSG00000135077,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000096996,ENSG00000134352,ENSG00000204472,ENSG00000013725,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000172936,ENSG00000127666,ENSG00000123338,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000175104 |
| GO:0051239 | regulation of multicellular organismal process | 0.0000311 | 3356 | 712 | 186 | 0.2612360 | 0.0554231 | GO:BP | ENSG00000004468,ENSG00000156587,ENSG00000113721,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000183688,ENSG00000007402,ENSG00000092010,ENSG00000073861,ENSG00000163599,ENSG00000117724,ENSG00000125347,ENSG00000180739,ENSG00000179218,ENSG00000159674,ENSG00000135077,ENSG00000147459,ENSG00000154451,ENSG00000089692,ENSG00000182054,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000159216,ENSG00000160014,ENSG00000173482,ENSG00000130164,ENSG00000115415,ENSG00000069702,ENSG00000091129,ENSG00000100911,ENSG00000221866,ENSG00000205336,ENSG00000164111,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000169252,ENSG00000196924,ENSG00000137265,ENSG00000118193,ENSG00000112029,ENSG00000120057,ENSG00000186470,ENSG00000150093,ENSG00000105409,ENSG00000123609,ENSG00000096996,ENSG00000165617,ENSG00000125249,ENSG00000173114,ENSG00000133321,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000112139,ENSG00000099194,ENSG00000232810,ENSG00000183691,ENSG00000117228,ENSG00000204397,ENSG00000111640,ENSG00000183734,ENSG00000134352,ENSG00000103769,ENSG00000108518,ENSG00000116288,ENSG00000134321,ENSG00000175793,ENSG00000169855,ENSG00000204264,ENSG00000077984,ENSG00000170312,ENSG00000105887,ENSG00000155846,ENSG00000122223,ENSG00000185885,ENSG00000141576,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000061337,ENSG00000055332,ENSG00000242372,ENSG00000169230,ENSG00000153094,ENSG00000123131,ENSG00000148400,ENSG00000167723,ENSG00000204472,ENSG00000121297,ENSG00000163041,ENSG00000044574,ENSG00000171246,ENSG00000116030,ENSG00000007968,ENSG00000118263,ENSG00000166710,ENSG00000073803,ENSG00000163823,ENSG00000166974,ENSG00000126016,ENSG00000241258,ENSG00000138071,ENSG00000107317,ENSG00000111348,ENSG00000156234,ENSG00000021355,ENSG00000185650,ENSG00000074800,ENSG00000105220,ENSG00000158869,ENSG00000136717,ENSG00000071994,ENSG00000168421,ENSG00000013725,ENSG00000130005,ENSG00000067560,ENSG00000132932,ENSG00000127952,ENSG00000114166,ENSG00000213719,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000122122,ENSG00000122877,ENSG00000171617,ENSG00000141736,ENSG00000204592,ENSG00000213626,ENSG00000187608,ENSG00000157873,ENSG00000162676,ENSG00000111863,ENSG00000106462,ENSG00000042753,ENSG00000153310,ENSG00000070831,ENSG00000172936,ENSG00000124920,ENSG00000151239,ENSG00000197043,ENSG00000066279,ENSG00000113369,ENSG00000096968,ENSG00000176542,ENSG00000079999,ENSG00000165527,ENSG00000168329,ENSG00000127666,ENSG00000105697,ENSG00000223496,ENSG00000116670,ENSG00000132386,ENSG00000123338,ENSG00000171943,ENSG00000128272,ENSG00000142867,ENSG00000111335,ENSG00000138646,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000091127,ENSG00000213366,ENSG00000127951,ENSG00000197409,ENSG00000150756,ENSG00000131873,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000155090,ENSG00000028137,ENSG00000147889,ENSG00000140575,ENSG00000137193,ENSG00000175104,ENSG00000110218,ENSG00000169554,ENSG00000166794,ENSG00000170485,ENSG00000081985 |
| GO:0032946 | positive regulation of mononuclear cell proliferation | 0.0000320 | 137 | 712 | 20 | 0.0280899 | 0.1459854 | GO:BP | ENSG00000004468,ENSG00000135077,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000096996,ENSG00000134352,ENSG00000204472,ENSG00000013725,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000172936,ENSG00000127666,ENSG00000123338,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000175104 |
| GO:0010941 | regulation of cell death | 0.0000327 | 1757 | 712 | 111 | 0.1558989 | 0.0631759 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000119922,ENSG00000113721,ENSG00000117281,ENSG00000072110,ENSG00000163599,ENSG00000179218,ENSG00000126709,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000115415,ENSG00000119917,ENSG00000164111,ENSG00000101057,ENSG00000170315,ENSG00000105639,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000146674,ENSG00000118193,ENSG00000117984,ENSG00000150093,ENSG00000173848,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000183691,ENSG00000134308,ENSG00000204397,ENSG00000108179,ENSG00000111640,ENSG00000134352,ENSG00000084092,ENSG00000116288,ENSG00000103202,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000156463,ENSG00000187446,ENSG00000130402,ENSG00000071205,ENSG00000170312,ENSG00000164830,ENSG00000141576,ENSG00000070018,ENSG00000055332,ENSG00000169230,ENSG00000153094,ENSG00000065135,ENSG00000119335,ENSG00000148400,ENSG00000204472,ENSG00000089685,ENSG00000044574,ENSG00000163545,ENSG00000166598,ENSG00000129675,ENSG00000118971,ENSG00000196954,ENSG00000185650,ENSG00000074800,ENSG00000105220,ENSG00000158869,ENSG00000145649,ENSG00000136717,ENSG00000071994,ENSG00000158006,ENSG00000100385,ENSG00000011485,ENSG00000067560,ENSG00000127952,ENSG00000165304,ENSG00000185507,ENSG00000204642,ENSG00000168961,ENSG00000131747,ENSG00000132792,ENSG00000103495,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000178719,ENSG00000096968,ENSG00000168329,ENSG00000138617,ENSG00000132386,ENSG00000123338,ENSG00000128272,ENSG00000134049,ENSG00000142867,ENSG00000114126,ENSG00000126432,ENSG00000172531,ENSG00000254087,ENSG00000160255,ENSG00000177076,ENSG00000172667,ENSG00000198851,ENSG00000196839,ENSG00000028137,ENSG00000147889,ENSG00000137193,ENSG00000175104,ENSG00000078124,ENSG00000127084,ENSG00000170485 |
| GO:0048583 | regulation of response to stimulus | 0.0000328 | 4421 | 712 | 233 | 0.3272472 | 0.0527030 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000179344,ENSG00000138496,ENSG00000113721,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000198826,ENSG00000092010,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000179218,ENSG00000002834,ENSG00000126709,ENSG00000159674,ENSG00000135077,ENSG00000160932,ENSG00000154451,ENSG00000100427,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000072135,ENSG00000203747,ENSG00000159216,ENSG00000160014,ENSG00000130164,ENSG00000115415,ENSG00000155629,ENSG00000069702,ENSG00000100911,ENSG00000221866,ENSG00000205336,ENSG00000164111,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000105639,ENSG00000117632,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000118193,ENSG00000112029,ENSG00000120057,ENSG00000127947,ENSG00000186470,ENSG00000150093,ENSG00000123609,ENSG00000173848,ENSG00000096996,ENSG00000165617,ENSG00000125249,ENSG00000111206,ENSG00000138795,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000183691,ENSG00000134539,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000204397,ENSG00000108179,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000153563,ENSG00000128284,ENSG00000131171,ENSG00000189319,ENSG00000005844,ENSG00000103148,ENSG00000116288,ENSG00000111602,ENSG00000073008,ENSG00000213390,ENSG00000134321,ENSG00000175793,ENSG00000169855,ENSG00000023572,ENSG00000152465,ENSG00000156463,ENSG00000204264,ENSG00000051341,ENSG00000077984,ENSG00000187446,ENSG00000130402,ENSG00000071205,ENSG00000170312,ENSG00000105887,ENSG00000167618,ENSG00000185885,ENSG00000164830,ENSG00000172116,ENSG00000070018,ENSG00000055332,ENSG00000239713,ENSG00000169230,ENSG00000153094,ENSG00000065135,ENSG00000213445,ENSG00000213281,ENSG00000159200,ENSG00000148400,ENSG00000204472,ENSG00000089685,ENSG00000044574,ENSG00000171246,ENSG00000116030,ENSG00000118263,ENSG00000132274,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000073803,ENSG00000152778,ENSG00000185745,ENSG00000163823,ENSG00000166974,ENSG00000180667,ENSG00000129422,ENSG00000126016,ENSG00000138071,ENSG00000166598,ENSG00000111348,ENSG00000156234,ENSG00000129675,ENSG00000196954,ENSG00000074800,ENSG00000158869,ENSG00000168421,ENSG00000013725,ENSG00000134909,ENSG00000163131,ENSG00000184916,ENSG00000198821,ENSG00000011485,ENSG00000067560,ENSG00000197417,ENSG00000127952,ENSG00000114166,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000122122,ENSG00000165283,ENSG00000141736,ENSG00000204592,ENSG00000132182,ENSG00000158321,ENSG00000174371,ENSG00000213626,ENSG00000167286,ENSG00000157873,ENSG00000103495,ENSG00000162676,ENSG00000111863,ENSG00000106462,ENSG00000153310,ENSG00000070831,ENSG00000172936,ENSG00000151239,ENSG00000171302,ENSG00000178719,ENSG00000054965,ENSG00000066279,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000128394,ENSG00000176641,ENSG00000170837,ENSG00000165527,ENSG00000117155,ENSG00000105612,ENSG00000168329,ENSG00000127666,ENSG00000105697,ENSG00000223496,ENSG00000026751,ENSG00000148908,ENSG00000102931,ENSG00000125648,ENSG00000116670,ENSG00000055163,ENSG00000132386,ENSG00000123338,ENSG00000128272,ENSG00000142867,ENSG00000110852,ENSG00000114126,ENSG00000138646,ENSG00000049541,ENSG00000172531,ENSG00000137309,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000143248,ENSG00000213366,ENSG00000111796,ENSG00000127951,ENSG00000101082,ENSG00000131019,ENSG00000131873,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000136104,ENSG00000242574,ENSG00000135960,ENSG00000028137,ENSG00000160753,ENSG00000132256,ENSG00000147889,ENSG00000140575,ENSG00000175104,ENSG00000169554,ENSG00000127084,ENSG00000170485 |
| GO:0002821 | positive regulation of adaptive immune response | 0.0000332 | 102 | 712 | 17 | 0.0238764 | 0.1666667 | GO:BP | ENSG00000179344,ENSG00000073861,ENSG00000096996,ENSG00000232810,ENSG00000134352,ENSG00000073008,ENSG00000134321,ENSG00000166710,ENSG00000158869,ENSG00000204642,ENSG00000122122,ENSG00000204592,ENSG00000153310,ENSG00000223496,ENSG00000116670,ENSG00000196839,ENSG00000175104 |
| GO:0001906 | cell killing | 0.0000336 | 163 | 712 | 22 | 0.0308989 | 0.1349693 | GO:BP | ENSG00000100453,ENSG00000117281,ENSG00000115523,ENSG00000135077,ENSG00000089692,ENSG00000096996,ENSG00000111537,ENSG00000189430,ENSG00000111640,ENSG00000196230,ENSG00000180644,ENSG00000073008,ENSG00000153094,ENSG00000166710,ENSG00000100342,ENSG00000204642,ENSG00000168961,ENSG00000204592,ENSG00000153310,ENSG00000105697,ENSG00000026751,ENSG00000131019 |
| GO:0002228 | natural killer cell mediated immunity | 0.0000478 | 62 | 712 | 13 | 0.0182584 | 0.2096774 | GO:BP | ENSG00000100453,ENSG00000117281,ENSG00000135077,ENSG00000089692,ENSG00000189430,ENSG00000134539,ENSG00000196230,ENSG00000073008,ENSG00000204642,ENSG00000168961,ENSG00000204592,ENSG00000026751,ENSG00000131019 |
| GO:0002367 | cytokine production involved in immune response | 0.0000494 | 105 | 712 | 17 | 0.0238764 | 0.1619048 | GO:BP | ENSG00000117281,ENSG00000073861,ENSG00000159674,ENSG00000019582,ENSG00000105639,ENSG00000232810,ENSG00000134321,ENSG00000166710,ENSG00000158869,ENSG00000204642,ENSG00000122122,ENSG00000204592,ENSG00000157873,ENSG00000127666,ENSG00000142867,ENSG00000028137,ENSG00000175104 |
| GO:0051716 | cellular response to stimulus | 0.0000495 | 7772 | 712 | 372 | 0.5224719 | 0.0478641 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000179344,ENSG00000156587,ENSG00000119922,ENSG00000100450,ENSG00000138496,ENSG00000113721,ENSG00000117281,ENSG00000196126,ENSG00000198826,ENSG00000092010,ENSG00000073861,ENSG00000156886,ENSG00000163599,ENSG00000132530,ENSG00000125347,ENSG00000108679,ENSG00000100321,ENSG00000180739,ENSG00000109956,ENSG00000179218,ENSG00000115523,ENSG00000002834,ENSG00000126709,ENSG00000159674,ENSG00000135077,ENSG00000160932,ENSG00000165891,ENSG00000147459,ENSG00000154451,ENSG00000162654,ENSG00000100427,ENSG00000134184,ENSG00000155657,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000072135,ENSG00000203747,ENSG00000159216,ENSG00000151502,ENSG00000160014,ENSG00000173482,ENSG00000130164,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000155629,ENSG00000186469,ENSG00000069702,ENSG00000100911,ENSG00000221866,ENSG00000205336,ENSG00000164111,ENSG00000113368,ENSG00000101057,ENSG00000177156,ENSG00000163029,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000166503,ENSG00000213512,ENSG00000105639,ENSG00000117632,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000118193,ENSG00000112029,ENSG00000120057,ENSG00000127947,ENSG00000186470,ENSG00000150093,ENSG00000136167,ENSG00000211746,ENSG00000167461,ENSG00000105409,ENSG00000123609,ENSG00000173848,ENSG00000096996,ENSG00000165617,ENSG00000125249,ENSG00000111206,ENSG00000172757,ENSG00000138795,ENSG00000211745,ENSG00000110090,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000189430,ENSG00000232810,ENSG00000183691,ENSG00000134539,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000126787,ENSG00000211721,ENSG00000204397,ENSG00000100749,ENSG00000108179,ENSG00000111640,ENSG00000118777,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000153563,ENSG00000103769,ENSG00000108518,ENSG00000117226,ENSG00000128284,ENSG00000131171,ENSG00000189319,ENSG00000005844,ENSG00000130592,ENSG00000103148,ENSG00000211747,ENSG00000185201,ENSG00000116288,ENSG00000171596,ENSG00000111602,ENSG00000213390,ENSG00000135114,ENSG00000134321,ENSG00000175793,ENSG00000169855,ENSG00000103966,ENSG00000023572,ENSG00000100918,ENSG00000152465,ENSG00000156463,ENSG00000204264,ENSG00000051341,ENSG00000188191,ENSG00000114978,ENSG00000237254,ENSG00000187446,ENSG00000130402,ENSG00000071205,ENSG00000170312,ENSG00000105887,ENSG00000155846,ENSG00000122223,ENSG00000185885,ENSG00000185651,ENSG00000164830,ENSG00000117394,ENSG00000172116,ENSG00000131944,ENSG00000070018,ENSG00000165949,ENSG00000092853,ENSG00000055332,ENSG00000169230,ENSG00000153094,ENSG00000123416,ENSG00000065135,ENSG00000213445,ENSG00000104687,ENSG00000213281,ENSG00000123131,ENSG00000159200,ENSG00000148400,ENSG00000157601,ENSG00000041353,ENSG00000089127,ENSG00000152256,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000044574,ENSG00000133315,ENSG00000171246,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000072958,ENSG00000132274,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000073803,ENSG00000159618,ENSG00000104805,ENSG00000163545,ENSG00000152778,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000166974,ENSG00000166454,ENSG00000180667,ENSG00000129422,ENSG00000154001,ENSG00000126016,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000129007,ENSG00000131236,ENSG00000110448,ENSG00000111348,ENSG00000148730,ENSG00000156234,ENSG00000129675,ENSG00000196954,ENSG00000183475,ENSG00000093009,ENSG00000185650,ENSG00000100605,ENSG00000125871,ENSG00000111331,ENSG00000074800,ENSG00000143476,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000053254,ENSG00000116983,ENSG00000168421,ENSG00000013725,ENSG00000134909,ENSG00000163131,ENSG00000170881,ENSG00000100385,ENSG00000125148,ENSG00000139921,ENSG00000131504,ENSG00000184916,ENSG00000198821,ENSG00000011485,ENSG00000067560,ENSG00000197417,ENSG00000213928,ENSG00000127952,ENSG00000114166,ENSG00000189283,ENSG00000213719,ENSG00000165304,ENSG00000134202,ENSG00000172794,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000006625,ENSG00000168961,ENSG00000115339,ENSG00000172270,ENSG00000122877,ENSG00000165283,ENSG00000131747,ENSG00000141736,ENSG00000204592,ENSG00000132182,ENSG00000103994,ENSG00000158321,ENSG00000174371,ENSG00000213626,ENSG00000167286,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000139579,ENSG00000103495,ENSG00000162676,ENSG00000111863,ENSG00000106462,ENSG00000042753,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000101079,ENSG00000179583,ENSG00000171302,ENSG00000178719,ENSG00000141030,ENSG00000197043,ENSG00000054965,ENSG00000132670,ENSG00000066279,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000176641,ENSG00000109674,ENSG00000079999,ENSG00000170837,ENSG00000165527,ENSG00000117155,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000105697,ENSG00000127022,ENSG00000197956,ENSG00000148908,ENSG00000196072,ENSG00000138617,ENSG00000102931,ENSG00000125648,ENSG00000116670,ENSG00000055163,ENSG00000090520,ENSG00000132386,ENSG00000256436,ENSG00000123338,ENSG00000128272,ENSG00000142867,ENSG00000111335,ENSG00000114126,ENSG00000126432,ENSG00000049541,ENSG00000104738,ENSG00000119318,ENSG00000172531,ENSG00000168765,ENSG00000137309,ENSG00000041357,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000143248,ENSG00000213366,ENSG00000111796,ENSG00000177076,ENSG00000155660,ENSG00000101082,ENSG00000197409,ENSG00000172667,ENSG00000131873,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000143321,ENSG00000136104,ENSG00000155090,ENSG00000148218,ENSG00000147168,ENSG00000177674,ENSG00000135960,ENSG00000028137,ENSG00000160753,ENSG00000178685,ENSG00000132256,ENSG00000147889,ENSG00000140575,ENSG00000137193,ENSG00000160404,ENSG00000111450,ENSG00000175104,ENSG00000169554,ENSG00000127084,ENSG00000113387,ENSG00000111859,ENSG00000170485,ENSG00000112759,ENSG00000081985 |
| GO:0042129 | regulation of T cell proliferation | 0.0000495 | 167 | 712 | 22 | 0.0308989 | 0.1317365 | GO:BP | ENSG00000196126,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000096996,ENSG00000134352,ENSG00000204472,ENSG00000013725,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000123338,ENSG00000198851,ENSG00000242574,ENSG00000028137,ENSG00000147889,ENSG00000175104 |
| GO:0051336 | regulation of hydrolase activity | 0.0000547 | 1296 | 712 | 87 | 0.1221910 | 0.0671296 | GO:BP | ENSG00000113721,ENSG00000198826,ENSG00000092010,ENSG00000126709,ENSG00000147459,ENSG00000117560,ENSG00000160014,ENSG00000100911,ENSG00000221866,ENSG00000146674,ENSG00000117984,ENSG00000150093,ENSG00000173848,ENSG00000138795,ENSG00000111537,ENSG00000179051,ENSG00000232810,ENSG00000204397,ENSG00000108179,ENSG00000111640,ENSG00000132646,ENSG00000108518,ENSG00000103148,ENSG00000116288,ENSG00000171596,ENSG00000213390,ENSG00000135114,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000156463,ENSG00000204264,ENSG00000077984,ENSG00000187446,ENSG00000071205,ENSG00000155846,ENSG00000163359,ENSG00000185304,ENSG00000055332,ENSG00000169230,ENSG00000153094,ENSG00000213445,ENSG00000159200,ENSG00000119335,ENSG00000089127,ENSG00000089685,ENSG00000185745,ENSG00000166974,ENSG00000154001,ENSG00000126016,ENSG00000166598,ENSG00000157985,ENSG00000111348,ENSG00000156234,ENSG00000129675,ENSG00000021355,ENSG00000196954,ENSG00000111331,ENSG00000105220,ENSG00000145649,ENSG00000136717,ENSG00000071994,ENSG00000168421,ENSG00000134909,ENSG00000067560,ENSG00000127952,ENSG00000168961,ENSG00000141736,ENSG00000106462,ENSG00000178996,ENSG00000166035,ENSG00000096968,ENSG00000148908,ENSG00000055163,ENSG00000090520,ENSG00000132386,ENSG00000123338,ENSG00000142867,ENSG00000111335,ENSG00000126432,ENSG00000254087,ENSG00000143248,ENSG00000177076,ENSG00000147889,ENSG00000140575,ENSG00000127084,ENSG00000111859 |
| GO:0002703 | regulation of leukocyte mediated immunity | 0.0000548 | 195 | 712 | 24 | 0.0337079 | 0.1230769 | GO:BP | ENSG00000117281,ENSG00000073861,ENSG00000135077,ENSG00000089692,ENSG00000105639,ENSG00000096996,ENSG00000189430,ENSG00000232810,ENSG00000073008,ENSG00000134321,ENSG00000166710,ENSG00000158869,ENSG00000204642,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000153310,ENSG00000127666,ENSG00000223496,ENSG00000116670,ENSG00000254087,ENSG00000160255,ENSG00000028137,ENSG00000175104 |
| GO:0032633 | interleukin-4 production | 0.0000548 | 36 | 712 | 10 | 0.0140449 | 0.2777778 | GO:BP | ENSG00000196126,ENSG00000135077,ENSG00000137265,ENSG00000138795,ENSG00000148400,ENSG00000158869,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000198851 |
| GO:0043902 | positive regulation of multi-organism process | 0.0000572 | 539 | 712 | 46 | 0.0646067 | 0.0853432 | GO:BP | ENSG00000138496,ENSG00000117281,ENSG00000092010,ENSG00000125347,ENSG00000135077,ENSG00000154451,ENSG00000089692,ENSG00000019582,ENSG00000155629,ENSG00000100911,ENSG00000170315,ENSG00000137265,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000111640,ENSG00000180644,ENSG00000073008,ENSG00000134321,ENSG00000204264,ENSG00000153094,ENSG00000213281,ENSG00000148400,ENSG00000185745,ENSG00000166598,ENSG00000158869,ENSG00000163131,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000148175,ENSG00000131747,ENSG00000204592,ENSG00000162676,ENSG00000172936,ENSG00000164164,ENSG00000127666,ENSG00000142867,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000137312,ENSG00000132256,ENSG00000175104,ENSG00000166794 |
| GO:1902105 | regulation of leukocyte differentiation | 0.0000619 | 283 | 712 | 30 | 0.0421348 | 0.1060071 | GO:BP | ENSG00000176083,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000105639,ENSG00000137265,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000155846,ENSG00000169230,ENSG00000163823,ENSG00000185650,ENSG00000168421,ENSG00000067560,ENSG00000185507,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000123338,ENSG00000254087,ENSG00000127951,ENSG00000196839,ENSG00000155090,ENSG00000147889,ENSG00000175104 |
| GO:0046651 | lymphocyte proliferation | 0.0000619 | 283 | 712 | 30 | 0.0421348 | 0.1060071 | GO:BP | ENSG00000004468,ENSG00000196126,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000096996,ENSG00000138795,ENSG00000134352,ENSG00000204472,ENSG00000147065,ENSG00000013725,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000172936,ENSG00000127666,ENSG00000123338,ENSG00000254087,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000028137,ENSG00000147889,ENSG00000175104 |
| GO:0002706 | regulation of lymphocyte mediated immunity | 0.0000633 | 144 | 712 | 20 | 0.0280899 | 0.1388889 | GO:BP | ENSG00000117281,ENSG00000073861,ENSG00000135077,ENSG00000089692,ENSG00000096996,ENSG00000189430,ENSG00000232810,ENSG00000073008,ENSG00000134321,ENSG00000166710,ENSG00000158869,ENSG00000204642,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000153310,ENSG00000223496,ENSG00000116670,ENSG00000028137,ENSG00000175104 |
| GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II | 0.0000642 | 96 | 712 | 16 | 0.0224719 | 0.1666667 | GO:BP | ENSG00000179344,ENSG00000196126,ENSG00000089692,ENSG00000196735,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000117984,ENSG00000138160,ENSG00000072958,ENSG00000158869,ENSG00000163131,ENSG00000042753,ENSG00000127022,ENSG00000242574,ENSG00000175104 |
| GO:0032673 | regulation of interleukin-4 production | 0.0000655 | 29 | 712 | 9 | 0.0126404 | 0.3103448 | GO:BP | ENSG00000196126,ENSG00000135077,ENSG00000137265,ENSG00000138795,ENSG00000158869,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000198851 |
| GO:0042981 | regulation of apoptotic process | 0.0000681 | 1605 | 712 | 102 | 0.1432584 | 0.0635514 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000119922,ENSG00000113721,ENSG00000117281,ENSG00000072110,ENSG00000163599,ENSG00000179218,ENSG00000126709,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000115415,ENSG00000119917,ENSG00000164111,ENSG00000101057,ENSG00000170315,ENSG00000105639,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000146674,ENSG00000118193,ENSG00000117984,ENSG00000150093,ENSG00000173848,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000183691,ENSG00000134308,ENSG00000204397,ENSG00000108179,ENSG00000111640,ENSG00000134352,ENSG00000116288,ENSG00000103202,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000156463,ENSG00000130402,ENSG00000071205,ENSG00000170312,ENSG00000164830,ENSG00000141576,ENSG00000070018,ENSG00000055332,ENSG00000169230,ENSG00000153094,ENSG00000065135,ENSG00000119335,ENSG00000148400,ENSG00000204472,ENSG00000089685,ENSG00000044574,ENSG00000163545,ENSG00000166598,ENSG00000129675,ENSG00000118971,ENSG00000196954,ENSG00000185650,ENSG00000074800,ENSG00000105220,ENSG00000158869,ENSG00000145649,ENSG00000136717,ENSG00000071994,ENSG00000158006,ENSG00000100385,ENSG00000067560,ENSG00000127952,ENSG00000165304,ENSG00000185507,ENSG00000168961,ENSG00000131747,ENSG00000132792,ENSG00000103495,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000178719,ENSG00000096968,ENSG00000168329,ENSG00000123338,ENSG00000128272,ENSG00000134049,ENSG00000142867,ENSG00000114126,ENSG00000126432,ENSG00000172531,ENSG00000254087,ENSG00000177076,ENSG00000172667,ENSG00000198851,ENSG00000196839,ENSG00000028137,ENSG00000147889,ENSG00000137193,ENSG00000175104,ENSG00000127084 |
| GO:0050794 | regulation of cellular process | 0.0000691 | 11187 | 712 | 504 | 0.7078652 | 0.0450523 | GO:BP | ENSG00000172057,ENSG00000100453,ENSG00000004468,ENSG00000148773,ENSG00000179344,ENSG00000152217,ENSG00000119922,ENSG00000100450,ENSG00000138496,ENSG00000113721,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000183688,ENSG00000007402,ENSG00000198826,ENSG00000229474,ENSG00000092010,ENSG00000248905,ENSG00000072110,ENSG00000073861,ENSG00000156886,ENSG00000163599,ENSG00000132530,ENSG00000117724,ENSG00000125347,ENSG00000108679,ENSG00000100321,ENSG00000180739,ENSG00000179218,ENSG00000002834,ENSG00000126709,ENSG00000175274,ENSG00000184357,ENSG00000135077,ENSG00000090857,ENSG00000160932,ENSG00000165891,ENSG00000147459,ENSG00000154451,ENSG00000155657,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000182054,ENSG00000163421,ENSG00000123485,ENSG00000019582,ENSG00000142669,ENSG00000117560,ENSG00000144354,ENSG00000072135,ENSG00000164649,ENSG00000203747,ENSG00000159216,ENSG00000151502,ENSG00000160014,ENSG00000034510,ENSG00000173482,ENSG00000130164,ENSG00000127124,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000155629,ENSG00000186469,ENSG00000069702,ENSG00000091129,ENSG00000100911,ENSG00000197928,ENSG00000130511,ENSG00000221866,ENSG00000205336,ENSG00000164111,ENSG00000124191,ENSG00000198046,ENSG00000113368,ENSG00000101057,ENSG00000177156,ENSG00000163029,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000166503,ENSG00000156970,ENSG00000171848,ENSG00000125868,ENSG00000105639,ENSG00000117632,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000175550,ENSG00000118193,ENSG00000112029,ENSG00000120057,ENSG00000117984,ENSG00000127947,ENSG00000186470,ENSG00000157216,ENSG00000150093,ENSG00000136167,ENSG00000211746,ENSG00000121039,ENSG00000167461,ENSG00000123609,ENSG00000165512,ENSG00000173848,ENSG00000138160,ENSG00000096996,ENSG00000077312,ENSG00000165617,ENSG00000125249,ENSG00000173114,ENSG00000111206,ENSG00000133321,ENSG00000172757,ENSG00000138795,ENSG00000211745,ENSG00000110090,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000112139,ENSG00000189430,ENSG00000232810,ENSG00000183691,ENSG00000134539,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000126787,ENSG00000176890,ENSG00000211721,ENSG00000204397,ENSG00000176293,ENSG00000100749,ENSG00000108179,ENSG00000111640,ENSG00000183734,ENSG00000172292,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000153563,ENSG00000103769,ENSG00000100380,ENSG00000108518,ENSG00000183741,ENSG00000128284,ENSG00000131171,ENSG00000189319,ENSG00000005844,ENSG00000130592,ENSG00000103148,ENSG00000211747,ENSG00000084092,ENSG00000185201,ENSG00000116288,ENSG00000196230,ENSG00000171596,ENSG00000111602,ENSG00000103202,ENSG00000213390,ENSG00000135114,ENSG00000134321,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000103966,ENSG00000124575,ENSG00000189420,ENSG00000023572,ENSG00000152465,ENSG00000156463,ENSG00000143543,ENSG00000204264,ENSG00000143742,ENSG00000051341,ENSG00000196976,ENSG00000188191,ENSG00000077984,ENSG00000114978,ENSG00000237254,ENSG00000187446,ENSG00000130402,ENSG00000011426,ENSG00000071205,ENSG00000170312,ENSG00000105887,ENSG00000155846,ENSG00000122223,ENSG00000136436,ENSG00000185885,ENSG00000163359,ENSG00000185651,ENSG00000164830,ENSG00000141576,ENSG00000117394,ENSG00000172116,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000125462,ENSG00000165949,ENSG00000092853,ENSG00000061337,ENSG00000215305,ENSG00000055332,ENSG00000239713,ENSG00000242372,ENSG00000169230,ENSG00000153094,ENSG00000065135,ENSG00000213445,ENSG00000104687,ENSG00000213281,ENSG00000123131,ENSG00000159200,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000164211,ENSG00000041353,ENSG00000089127,ENSG00000152256,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000121297,ENSG00000163041,ENSG00000044574,ENSG00000188612,ENSG00000171246,ENSG00000130741,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000132274,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000073803,ENSG00000159618,ENSG00000104805,ENSG00000179632,ENSG00000163545,ENSG00000152778,ENSG00000185745,ENSG00000163823,ENSG00000233757,ENSG00000147065,ENSG00000166974,ENSG00000142556,ENSG00000166454,ENSG00000128578,ENSG00000180667,ENSG00000129422,ENSG00000166197,ENSG00000154001,ENSG00000126016,ENSG00000241258,ENSG00000253626,ENSG00000073910,ENSG00000131931,ENSG00000171970,ENSG00000138071,ENSG00000166598,ENSG00000129007,ENSG00000131236,ENSG00000110448,ENSG00000111348,ENSG00000148730,ENSG00000156234,ENSG00000108798,ENSG00000129675,ENSG00000118971,ENSG00000129534,ENSG00000021355,ENSG00000196954,ENSG00000183475,ENSG00000093009,ENSG00000185650,ENSG00000100605,ENSG00000111331,ENSG00000074800,ENSG00000143476,ENSG00000172803,ENSG00000122952,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000171222,ENSG00000053254,ENSG00000145649,ENSG00000136717,ENSG00000116983,ENSG00000071994,ENSG00000168421,ENSG00000013725,ENSG00000134909,ENSG00000158006,ENSG00000163131,ENSG00000170881,ENSG00000100385,ENSG00000125148,ENSG00000139921,ENSG00000131504,ENSG00000184916,ENSG00000180574,ENSG00000075151,ENSG00000198821,ENSG00000011485,ENSG00000067560,ENSG00000132932,ENSG00000197417,ENSG00000213928,ENSG00000125944,ENSG00000127952,ENSG00000114166,ENSG00000189283,ENSG00000213719,ENSG00000165304,ENSG00000172794,ENSG00000075340,ENSG00000133026,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000144597,ENSG00000204642,ENSG00000115267,ENSG00000204256,ENSG00000087302,ENSG00000006625,ENSG00000168961,ENSG00000115339,ENSG00000122122,ENSG00000172270,ENSG00000122877,ENSG00000165283,ENSG00000173517,ENSG00000172795,ENSG00000131747,ENSG00000171617,ENSG00000141736,ENSG00000162702,ENSG00000204592,ENSG00000132182,ENSG00000132792,ENSG00000103994,ENSG00000158321,ENSG00000174371,ENSG00000118564,ENSG00000160877,ENSG00000213626,ENSG00000167286,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000139579,ENSG00000103495,ENSG00000162676,ENSG00000111863,ENSG00000068489,ENSG00000106462,ENSG00000042753,ENSG00000153310,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000079691,ENSG00000172936,ENSG00000124920,ENSG00000171169,ENSG00000151239,ENSG00000101079,ENSG00000243660,ENSG00000179583,ENSG00000171302,ENSG00000178719,ENSG00000141030,ENSG00000197043,ENSG00000054965,ENSG00000132670,ENSG00000066279,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000176542,ENSG00000128394,ENSG00000258289,ENSG00000176641,ENSG00000079999,ENSG00000113068,ENSG00000170837,ENSG00000165527,ENSG00000117155,ENSG00000162385,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000109084,ENSG00000105697,ENSG00000223496,ENSG00000127022,ENSG00000197956,ENSG00000148908,ENSG00000196072,ENSG00000138617,ENSG00000184897,ENSG00000102931,ENSG00000125648,ENSG00000116670,ENSG00000072571,ENSG00000055163,ENSG00000184640,ENSG00000090520,ENSG00000132386,ENSG00000049239,ENSG00000256436,ENSG00000123338,ENSG00000140450,ENSG00000171943,ENSG00000128272,ENSG00000134049,ENSG00000148337,ENSG00000124688,ENSG00000142867,ENSG00000111335,ENSG00000114126,ENSG00000143740,ENSG00000126432,ENSG00000138646,ENSG00000049541,ENSG00000119318,ENSG00000172531,ENSG00000178691,ENSG00000129968,ENSG00000137309,ENSG00000041357,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000152601,ENSG00000143248,ENSG00000091127,ENSG00000213366,ENSG00000182628,ENSG00000111796,ENSG00000177076,ENSG00000127951,ENSG00000137310,ENSG00000155660,ENSG00000101082,ENSG00000164576,ENSG00000197409,ENSG00000172667,ENSG00000150756,ENSG00000131873,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000143321,ENSG00000136104,ENSG00000089693,ENSG00000155090,ENSG00000148218,ENSG00000242574,ENSG00000147168,ENSG00000177674,ENSG00000135960,ENSG00000011007,ENSG00000028137,ENSG00000160753,ENSG00000178685,ENSG00000169223,ENSG00000132256,ENSG00000147889,ENSG00000139926,ENSG00000140575,ENSG00000137193,ENSG00000160404,ENSG00000111450,ENSG00000155096,ENSG00000175104,ENSG00000078124,ENSG00000110218,ENSG00000169554,ENSG00000127084,ENSG00000113387,ENSG00000111859,ENSG00000147180,ENSG00000170485,ENSG00000130818,ENSG00000112759,ENSG00000081985 |
| GO:0002824 | positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 0.0000718 | 97 | 712 | 16 | 0.0224719 | 0.1649485 | GO:BP | ENSG00000179344,ENSG00000073861,ENSG00000096996,ENSG00000232810,ENSG00000073008,ENSG00000134321,ENSG00000166710,ENSG00000158869,ENSG00000204642,ENSG00000122122,ENSG00000204592,ENSG00000153310,ENSG00000223496,ENSG00000116670,ENSG00000196839,ENSG00000175104 |
| GO:0045088 | regulation of innate immune response | 0.0000721 | 444 | 712 | 40 | 0.0561798 | 0.0900901 | GO:BP | ENSG00000138496,ENSG00000117281,ENSG00000092010,ENSG00000125347,ENSG00000135077,ENSG00000154451,ENSG00000089692,ENSG00000115415,ENSG00000155629,ENSG00000100911,ENSG00000170315,ENSG00000137265,ENSG00000123609,ENSG00000111537,ENSG00000189430,ENSG00000073008,ENSG00000134321,ENSG00000204264,ENSG00000213281,ENSG00000116030,ENSG00000166598,ENSG00000158869,ENSG00000163131,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000204592,ENSG00000162676,ENSG00000172936,ENSG00000096968,ENSG00000164164,ENSG00000127666,ENSG00000142867,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000137312,ENSG00000132256,ENSG00000175104 |
| GO:0032943 | mononuclear cell proliferation | 0.0000726 | 286 | 712 | 30 | 0.0421348 | 0.1048951 | GO:BP | ENSG00000004468,ENSG00000196126,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000096996,ENSG00000138795,ENSG00000134352,ENSG00000204472,ENSG00000147065,ENSG00000013725,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000172936,ENSG00000127666,ENSG00000123338,ENSG00000254087,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000028137,ENSG00000147889,ENSG00000175104 |
| GO:0043067 | regulation of programmed cell death | 0.0000808 | 1633 | 712 | 103 | 0.1446629 | 0.0630741 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000119922,ENSG00000113721,ENSG00000117281,ENSG00000072110,ENSG00000163599,ENSG00000179218,ENSG00000126709,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000115415,ENSG00000119917,ENSG00000164111,ENSG00000101057,ENSG00000170315,ENSG00000105639,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000146674,ENSG00000118193,ENSG00000117984,ENSG00000150093,ENSG00000173848,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000183691,ENSG00000134308,ENSG00000204397,ENSG00000108179,ENSG00000111640,ENSG00000134352,ENSG00000116288,ENSG00000103202,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000156463,ENSG00000130402,ENSG00000071205,ENSG00000170312,ENSG00000164830,ENSG00000141576,ENSG00000070018,ENSG00000055332,ENSG00000169230,ENSG00000153094,ENSG00000065135,ENSG00000119335,ENSG00000148400,ENSG00000204472,ENSG00000089685,ENSG00000044574,ENSG00000163545,ENSG00000166598,ENSG00000129675,ENSG00000118971,ENSG00000196954,ENSG00000185650,ENSG00000074800,ENSG00000105220,ENSG00000158869,ENSG00000145649,ENSG00000136717,ENSG00000071994,ENSG00000158006,ENSG00000100385,ENSG00000067560,ENSG00000127952,ENSG00000165304,ENSG00000185507,ENSG00000168961,ENSG00000131747,ENSG00000132792,ENSG00000103495,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000178719,ENSG00000096968,ENSG00000168329,ENSG00000123338,ENSG00000128272,ENSG00000134049,ENSG00000142867,ENSG00000114126,ENSG00000126432,ENSG00000172531,ENSG00000254087,ENSG00000177076,ENSG00000172667,ENSG00000198851,ENSG00000196839,ENSG00000028137,ENSG00000147889,ENSG00000137193,ENSG00000175104,ENSG00000078124,ENSG00000127084 |
| GO:0002708 | positive regulation of lymphocyte mediated immunity | 0.0000808 | 98 | 712 | 16 | 0.0224719 | 0.1632653 | GO:BP | ENSG00000117281,ENSG00000073861,ENSG00000089692,ENSG00000096996,ENSG00000232810,ENSG00000073008,ENSG00000134321,ENSG00000166710,ENSG00000158869,ENSG00000204642,ENSG00000122122,ENSG00000204592,ENSG00000153310,ENSG00000223496,ENSG00000116670,ENSG00000175104 |
| GO:0031341 | regulation of cell killing | 0.0000830 | 87 | 712 | 15 | 0.0210674 | 0.1724138 | GO:BP | ENSG00000117281,ENSG00000135077,ENSG00000089692,ENSG00000096996,ENSG00000111537,ENSG00000189430,ENSG00000111640,ENSG00000180644,ENSG00000073008,ENSG00000153094,ENSG00000166710,ENSG00000204642,ENSG00000168961,ENSG00000204592,ENSG00000153310 |
| GO:0031343 | positive regulation of cell killing | 0.0000843 | 56 | 712 | 12 | 0.0168539 | 0.2142857 | GO:BP | ENSG00000117281,ENSG00000089692,ENSG00000096996,ENSG00000111537,ENSG00000111640,ENSG00000180644,ENSG00000073008,ENSG00000153094,ENSG00000166710,ENSG00000204642,ENSG00000204592,ENSG00000153310 |
| GO:0045619 | regulation of lymphocyte differentiation | 0.0000951 | 175 | 712 | 22 | 0.0308989 | 0.1257143 | GO:BP | ENSG00000176083,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000105639,ENSG00000137265,ENSG00000096996,ENSG00000111537,ENSG00000169230,ENSG00000185650,ENSG00000168421,ENSG00000067560,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000123338,ENSG00000127951,ENSG00000196839,ENSG00000147889 |
| GO:0042267 | natural killer cell mediated cytotoxicity | 0.0001015 | 57 | 712 | 12 | 0.0168539 | 0.2105263 | GO:BP | ENSG00000100453,ENSG00000117281,ENSG00000135077,ENSG00000089692,ENSG00000189430,ENSG00000196230,ENSG00000073008,ENSG00000204642,ENSG00000168961,ENSG00000204592,ENSG00000026751,ENSG00000131019 |
| GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II | 0.0001021 | 100 | 712 | 16 | 0.0224719 | 0.1600000 | GO:BP | ENSG00000179344,ENSG00000196126,ENSG00000089692,ENSG00000196735,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000117984,ENSG00000138160,ENSG00000072958,ENSG00000158869,ENSG00000163131,ENSG00000042753,ENSG00000127022,ENSG00000242574,ENSG00000175104 |
| GO:0001909 | leukocyte mediated cytotoxicity | 0.0001161 | 101 | 712 | 16 | 0.0224719 | 0.1584158 | GO:BP | ENSG00000100453,ENSG00000117281,ENSG00000135077,ENSG00000089692,ENSG00000096996,ENSG00000189430,ENSG00000196230,ENSG00000180644,ENSG00000073008,ENSG00000166710,ENSG00000204642,ENSG00000168961,ENSG00000204592,ENSG00000153310,ENSG00000026751,ENSG00000131019 |
| GO:0022402 | cell cycle process | 0.0001227 | 1407 | 712 | 91 | 0.1278090 | 0.0646766 | GO:BP | ENSG00000148773,ENSG00000113721,ENSG00000092010,ENSG00000117724,ENSG00000125347,ENSG00000179218,ENSG00000165891,ENSG00000155657,ENSG00000160014,ENSG00000100911,ENSG00000101057,ENSG00000170315,ENSG00000156970,ENSG00000171848,ENSG00000117632,ENSG00000196924,ENSG00000118193,ENSG00000112029,ENSG00000150093,ENSG00000138160,ENSG00000165617,ENSG00000111206,ENSG00000172757,ENSG00000111537,ENSG00000179051,ENSG00000138180,ENSG00000126787,ENSG00000176890,ENSG00000100749,ENSG00000132646,ENSG00000103769,ENSG00000196230,ENSG00000111602,ENSG00000175793,ENSG00000100918,ENSG00000143543,ENSG00000204264,ENSG00000011426,ENSG00000170312,ENSG00000185651,ENSG00000092853,ENSG00000061337,ENSG00000153094,ENSG00000148400,ENSG00000204472,ENSG00000089685,ENSG00000166974,ENSG00000204899,ENSG00000206127,ENSG00000138071,ENSG00000118971,ENSG00000093009,ENSG00000185650,ENSG00000143476,ENSG00000122952,ENSG00000143228,ENSG00000053254,ENSG00000136717,ENSG00000067560,ENSG00000114166,ENSG00000165304,ENSG00000133026,ENSG00000113810,ENSG00000131747,ENSG00000139579,ENSG00000162676,ENSG00000068489,ENSG00000106462,ENSG00000178996,ENSG00000176101,ENSG00000070831,ENSG00000152253,ENSG00000066279,ENSG00000136824,ENSG00000117155,ENSG00000109805,ENSG00000121579,ENSG00000116670,ENSG00000072571,ENSG00000184640,ENSG00000124688,ENSG00000114126,ENSG00000049541,ENSG00000104738,ENSG00000178691,ENSG00000153044,ENSG00000041357,ENSG00000125354,ENSG00000136104,ENSG00000134690,ENSG00000147889 |
| GO:0018916 | nitrobenzene metabolic process | 0.0001257 | 4 | 712 | 4 | 0.0056180 | 1.0000000 | GO:BP | ENSG00000134184,ENSG00000134202,ENSG00000168765,ENSG00000213366 |
| GO:0002705 | positive regulation of leukocyte mediated immunity | 0.0001257 | 126 | 712 | 18 | 0.0252809 | 0.1428571 | GO:BP | ENSG00000117281,ENSG00000073861,ENSG00000089692,ENSG00000096996,ENSG00000232810,ENSG00000073008,ENSG00000134321,ENSG00000166710,ENSG00000158869,ENSG00000204642,ENSG00000122122,ENSG00000204592,ENSG00000153310,ENSG00000127666,ENSG00000223496,ENSG00000116670,ENSG00000160255,ENSG00000175104 |
| GO:0043933 | protein-containing complex subunit organization | 0.0001282 | 2047 | 712 | 122 | 0.1713483 | 0.0595994 | GO:BP | ENSG00000196169,ENSG00000196126,ENSG00000248905,ENSG00000117724,ENSG00000179218,ENSG00000184357,ENSG00000154451,ENSG00000100427,ENSG00000155657,ENSG00000123485,ENSG00000231925,ENSG00000019582,ENSG00000198513,ENSG00000034510,ENSG00000069702,ENSG00000170315,ENSG00000166503,ENSG00000171848,ENSG00000125868,ENSG00000117632,ENSG00000169252,ENSG00000160654,ENSG00000118193,ENSG00000112029,ENSG00000157216,ENSG00000136167,ENSG00000165617,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000100380,ENSG00000108518,ENSG00000116288,ENSG00000180644,ENSG00000103966,ENSG00000124575,ENSG00000105011,ENSG00000051341,ENSG00000187446,ENSG00000188312,ENSG00000011426,ENSG00000170312,ENSG00000105887,ENSG00000136436,ENSG00000117394,ENSG00000070018,ENSG00000215305,ENSG00000055332,ENSG00000242372,ENSG00000153094,ENSG00000119335,ENSG00000204472,ENSG00000163041,ENSG00000044574,ENSG00000130741,ENSG00000116030,ENSG00000132274,ENSG00000166710,ENSG00000111229,ENSG00000147065,ENSG00000204899,ENSG00000204822,ENSG00000253626,ENSG00000138071,ENSG00000156234,ENSG00000112031,ENSG00000129534,ENSG00000115155,ENSG00000093009,ENSG00000084623,ENSG00000158869,ENSG00000136717,ENSG00000100385,ENSG00000131504,ENSG00000180574,ENSG00000198821,ENSG00000067560,ENSG00000075340,ENSG00000204256,ENSG00000165283,ENSG00000148175,ENSG00000132963,ENSG00000132182,ENSG00000160877,ENSG00000167286,ENSG00000189369,ENSG00000042753,ENSG00000070831,ENSG00000079691,ENSG00000112996,ENSG00000151239,ENSG00000166035,ENSG00000074071,ENSG00000197043,ENSG00000096968,ENSG00000165527,ENSG00000127666,ENSG00000159111,ENSG00000184897,ENSG00000184640,ENSG00000123338,ENSG00000142867,ENSG00000109390,ENSG00000143740,ENSG00000198736,ENSG00000104738,ENSG00000119318,ENSG00000172531,ENSG00000153044,ENSG00000137309,ENSG00000189306,ENSG00000197409,ENSG00000137312,ENSG00000198851,ENSG00000232838,ENSG00000148218,ENSG00000242574,ENSG00000111450,ENSG00000110218,ENSG00000113387 |
| GO:0002504 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | 0.0001282 | 102 | 712 | 16 | 0.0224719 | 0.1568627 | GO:BP | ENSG00000179344,ENSG00000196126,ENSG00000089692,ENSG00000196735,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000117984,ENSG00000138160,ENSG00000072958,ENSG00000158869,ENSG00000163131,ENSG00000042753,ENSG00000127022,ENSG00000242574,ENSG00000175104 |
| GO:0048584 | positive regulation of response to stimulus | 0.0001392 | 2542 | 712 | 145 | 0.2036517 | 0.0570417 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000179344,ENSG00000138496,ENSG00000113721,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000179218,ENSG00000002834,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000203747,ENSG00000159216,ENSG00000160014,ENSG00000130164,ENSG00000155629,ENSG00000069702,ENSG00000100911,ENSG00000205336,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000186470,ENSG00000150093,ENSG00000173848,ENSG00000096996,ENSG00000165617,ENSG00000111206,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000134308,ENSG00000204397,ENSG00000108179,ENSG00000134352,ENSG00000132646,ENSG00000128284,ENSG00000131171,ENSG00000189319,ENSG00000116288,ENSG00000111602,ENSG00000073008,ENSG00000134321,ENSG00000175793,ENSG00000169855,ENSG00000156463,ENSG00000204264,ENSG00000130402,ENSG00000170312,ENSG00000055332,ENSG00000153094,ENSG00000213281,ENSG00000148400,ENSG00000204472,ENSG00000132274,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000073803,ENSG00000152778,ENSG00000163823,ENSG00000166974,ENSG00000138071,ENSG00000166598,ENSG00000156234,ENSG00000196954,ENSG00000158869,ENSG00000013725,ENSG00000163131,ENSG00000184916,ENSG00000198821,ENSG00000011485,ENSG00000067560,ENSG00000127952,ENSG00000114166,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000122122,ENSG00000165283,ENSG00000141736,ENSG00000204592,ENSG00000158321,ENSG00000167286,ENSG00000157873,ENSG00000103495,ENSG00000162676,ENSG00000106462,ENSG00000153310,ENSG00000070831,ENSG00000172936,ENSG00000171302,ENSG00000054965,ENSG00000066279,ENSG00000075624,ENSG00000096968,ENSG00000164164,ENSG00000170837,ENSG00000168329,ENSG00000127666,ENSG00000223496,ENSG00000102931,ENSG00000116670,ENSG00000055163,ENSG00000123338,ENSG00000142867,ENSG00000114126,ENSG00000172531,ENSG00000137309,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000213366,ENSG00000101082,ENSG00000131873,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000135960,ENSG00000160753,ENSG00000132256,ENSG00000147889,ENSG00000140575,ENSG00000175104,ENSG00000169554,ENSG00000170485 |
| GO:0050789 | regulation of biological process | 0.0001418 | 11940 | 712 | 530 | 0.7443820 | 0.0443886 | GO:BP | ENSG00000172057,ENSG00000100453,ENSG00000004468,ENSG00000148773,ENSG00000179344,ENSG00000152217,ENSG00000156587,ENSG00000119922,ENSG00000100450,ENSG00000138496,ENSG00000113721,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000183688,ENSG00000007402,ENSG00000198826,ENSG00000229474,ENSG00000092010,ENSG00000248905,ENSG00000072110,ENSG00000073861,ENSG00000156886,ENSG00000163599,ENSG00000132530,ENSG00000117724,ENSG00000125347,ENSG00000108679,ENSG00000100321,ENSG00000180739,ENSG00000179218,ENSG00000002834,ENSG00000126709,ENSG00000159674,ENSG00000175274,ENSG00000184357,ENSG00000135077,ENSG00000090857,ENSG00000160932,ENSG00000165891,ENSG00000147459,ENSG00000154451,ENSG00000100427,ENSG00000155657,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000182054,ENSG00000163421,ENSG00000123485,ENSG00000231925,ENSG00000019582,ENSG00000142669,ENSG00000117560,ENSG00000144354,ENSG00000072135,ENSG00000164649,ENSG00000203747,ENSG00000159216,ENSG00000151502,ENSG00000160014,ENSG00000034510,ENSG00000173482,ENSG00000130164,ENSG00000127124,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000155629,ENSG00000186469,ENSG00000069702,ENSG00000091129,ENSG00000100911,ENSG00000197928,ENSG00000130511,ENSG00000221866,ENSG00000205336,ENSG00000164111,ENSG00000124191,ENSG00000198046,ENSG00000113368,ENSG00000101057,ENSG00000177156,ENSG00000163029,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000166503,ENSG00000156970,ENSG00000171848,ENSG00000125868,ENSG00000105639,ENSG00000117632,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000175550,ENSG00000118193,ENSG00000112029,ENSG00000120057,ENSG00000117984,ENSG00000127947,ENSG00000186470,ENSG00000157216,ENSG00000150093,ENSG00000136167,ENSG00000211746,ENSG00000121039,ENSG00000167461,ENSG00000105409,ENSG00000123609,ENSG00000165512,ENSG00000173848,ENSG00000138160,ENSG00000096996,ENSG00000077312,ENSG00000165617,ENSG00000125249,ENSG00000173114,ENSG00000111206,ENSG00000133321,ENSG00000172757,ENSG00000138795,ENSG00000211745,ENSG00000110090,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000112139,ENSG00000189430,ENSG00000099194,ENSG00000232810,ENSG00000183691,ENSG00000134539,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000126787,ENSG00000176890,ENSG00000211721,ENSG00000204397,ENSG00000176293,ENSG00000100749,ENSG00000108179,ENSG00000111640,ENSG00000183734,ENSG00000172292,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000153563,ENSG00000103769,ENSG00000100380,ENSG00000108518,ENSG00000183741,ENSG00000128284,ENSG00000131171,ENSG00000189319,ENSG00000005844,ENSG00000130592,ENSG00000103148,ENSG00000211747,ENSG00000084092,ENSG00000185201,ENSG00000116288,ENSG00000196230,ENSG00000171596,ENSG00000180644,ENSG00000111602,ENSG00000103202,ENSG00000073008,ENSG00000213390,ENSG00000135114,ENSG00000134321,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000103966,ENSG00000124575,ENSG00000189420,ENSG00000023572,ENSG00000152465,ENSG00000156463,ENSG00000143543,ENSG00000204264,ENSG00000143742,ENSG00000051341,ENSG00000196976,ENSG00000188191,ENSG00000077984,ENSG00000114978,ENSG00000237254,ENSG00000187446,ENSG00000130402,ENSG00000011426,ENSG00000071205,ENSG00000170312,ENSG00000105887,ENSG00000167618,ENSG00000155846,ENSG00000122223,ENSG00000136436,ENSG00000185885,ENSG00000163359,ENSG00000185651,ENSG00000164830,ENSG00000141576,ENSG00000117394,ENSG00000172116,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000125462,ENSG00000165949,ENSG00000092853,ENSG00000061337,ENSG00000215305,ENSG00000055332,ENSG00000239713,ENSG00000242372,ENSG00000169230,ENSG00000153094,ENSG00000065135,ENSG00000213445,ENSG00000104687,ENSG00000213281,ENSG00000163520,ENSG00000123131,ENSG00000159200,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000164211,ENSG00000041353,ENSG00000089127,ENSG00000167723,ENSG00000152256,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000121297,ENSG00000163041,ENSG00000044574,ENSG00000188612,ENSG00000171246,ENSG00000130741,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000132274,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000073803,ENSG00000159618,ENSG00000104805,ENSG00000179632,ENSG00000163545,ENSG00000152778,ENSG00000185745,ENSG00000163823,ENSG00000233757,ENSG00000147065,ENSG00000166974,ENSG00000142556,ENSG00000166454,ENSG00000128578,ENSG00000180667,ENSG00000129422,ENSG00000166197,ENSG00000154001,ENSG00000126016,ENSG00000241258,ENSG00000253626,ENSG00000073910,ENSG00000131931,ENSG00000171970,ENSG00000138071,ENSG00000166598,ENSG00000129007,ENSG00000131236,ENSG00000110448,ENSG00000107317,ENSG00000111348,ENSG00000148730,ENSG00000156234,ENSG00000108798,ENSG00000129675,ENSG00000118971,ENSG00000129534,ENSG00000021355,ENSG00000196954,ENSG00000183475,ENSG00000093009,ENSG00000185650,ENSG00000100605,ENSG00000111331,ENSG00000074800,ENSG00000143476,ENSG00000172803,ENSG00000122952,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000171222,ENSG00000196449,ENSG00000053254,ENSG00000145649,ENSG00000136717,ENSG00000116983,ENSG00000071994,ENSG00000168421,ENSG00000013725,ENSG00000134909,ENSG00000158006,ENSG00000163131,ENSG00000170881,ENSG00000100385,ENSG00000130005,ENSG00000125148,ENSG00000139921,ENSG00000131504,ENSG00000184916,ENSG00000180574,ENSG00000075151,ENSG00000198821,ENSG00000011485,ENSG00000067560,ENSG00000132932,ENSG00000197417,ENSG00000213928,ENSG00000125944,ENSG00000127952,ENSG00000114166,ENSG00000189283,ENSG00000213719,ENSG00000165304,ENSG00000172794,ENSG00000075340,ENSG00000133026,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000144597,ENSG00000204642,ENSG00000115267,ENSG00000204256,ENSG00000087302,ENSG00000006625,ENSG00000168961,ENSG00000115339,ENSG00000122122,ENSG00000172270,ENSG00000122877,ENSG00000165283,ENSG00000173517,ENSG00000172795,ENSG00000148175,ENSG00000131747,ENSG00000171617,ENSG00000141736,ENSG00000162702,ENSG00000204592,ENSG00000132182,ENSG00000132792,ENSG00000103994,ENSG00000158321,ENSG00000174371,ENSG00000118564,ENSG00000160877,ENSG00000213626,ENSG00000167286,ENSG00000187608,ENSG00000157873,ENSG00000189369,ENSG00000198843,ENSG00000139579,ENSG00000103495,ENSG00000162676,ENSG00000111863,ENSG00000068489,ENSG00000106462,ENSG00000042753,ENSG00000153310,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000079691,ENSG00000172936,ENSG00000124920,ENSG00000170860,ENSG00000171169,ENSG00000151239,ENSG00000101079,ENSG00000164088,ENSG00000243660,ENSG00000179583,ENSG00000171302,ENSG00000178719,ENSG00000166035,ENSG00000141030,ENSG00000197043,ENSG00000054965,ENSG00000189266,ENSG00000132670,ENSG00000066279,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000176542,ENSG00000128394,ENSG00000258289,ENSG00000176641,ENSG00000079999,ENSG00000113068,ENSG00000170837,ENSG00000165527,ENSG00000117155,ENSG00000105612,ENSG00000162385,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000109084,ENSG00000105697,ENSG00000223496,ENSG00000127022,ENSG00000197956,ENSG00000026751,ENSG00000148908,ENSG00000196072,ENSG00000138617,ENSG00000184897,ENSG00000102931,ENSG00000125648,ENSG00000116670,ENSG00000072571,ENSG00000055163,ENSG00000184640,ENSG00000090520,ENSG00000132386,ENSG00000049239,ENSG00000256436,ENSG00000123338,ENSG00000140450,ENSG00000171943,ENSG00000128272,ENSG00000134049,ENSG00000148337,ENSG00000124688,ENSG00000142867,ENSG00000110852,ENSG00000111335,ENSG00000114126,ENSG00000143740,ENSG00000126432,ENSG00000145337,ENSG00000138646,ENSG00000049541,ENSG00000119318,ENSG00000172531,ENSG00000178691,ENSG00000129968,ENSG00000137309,ENSG00000041357,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000152601,ENSG00000143248,ENSG00000091127,ENSG00000213366,ENSG00000182628,ENSG00000111796,ENSG00000177076,ENSG00000127951,ENSG00000137310,ENSG00000155660,ENSG00000101082,ENSG00000164576,ENSG00000131019,ENSG00000197409,ENSG00000172667,ENSG00000150756,ENSG00000131873,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000143321,ENSG00000136104,ENSG00000089693,ENSG00000155090,ENSG00000148218,ENSG00000242574,ENSG00000147168,ENSG00000177674,ENSG00000135960,ENSG00000011007,ENSG00000028137,ENSG00000160753,ENSG00000178685,ENSG00000169223,ENSG00000132256,ENSG00000147889,ENSG00000139926,ENSG00000140575,ENSG00000137193,ENSG00000160404,ENSG00000111450,ENSG00000155096,ENSG00000175104,ENSG00000078124,ENSG00000110218,ENSG00000169554,ENSG00000127084,ENSG00000113387,ENSG00000166794,ENSG00000111859,ENSG00000147180,ENSG00000170485,ENSG00000130818,ENSG00000112759,ENSG00000081985 |
| GO:0071353 | cellular response to interleukin-4 | 0.0001418 | 32 | 712 | 9 | 0.0126404 | 0.2812500 | GO:BP | ENSG00000105639,ENSG00000138795,ENSG00000123416,ENSG00000044574,ENSG00000165030,ENSG00000197417,ENSG00000079999,ENSG00000148218,ENSG00000147168 |
| GO:0002366 | leukocyte activation involved in immune response | 0.0001452 | 704 | 712 | 54 | 0.0758427 | 0.0767045 | GO:BP | ENSG00000172057,ENSG00000176083,ENSG00000073861,ENSG00000100321,ENSG00000135077,ENSG00000105639,ENSG00000137265,ENSG00000117984,ENSG00000136167,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000005844,ENSG00000196230,ENSG00000134765,ENSG00000137563,ENSG00000122223,ENSG00000213281,ENSG00000123131,ENSG00000064666,ENSG00000072958,ENSG00000166710,ENSG00000138071,ENSG00000131236,ENSG00000021355,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000100299,ENSG00000163131,ENSG00000131504,ENSG00000067560,ENSG00000172794,ENSG00000204642,ENSG00000168961,ENSG00000148175,ENSG00000174371,ENSG00000171302,ENSG00000147234,ENSG00000127666,ENSG00000139370,ENSG00000223496,ENSG00000116670,ENSG00000123338,ENSG00000140284,ENSG00000254087,ENSG00000160255,ENSG00000140319,ENSG00000127951,ENSG00000196839,ENSG00000148218,ENSG00000242574,ENSG00000028137,ENSG00000140575 |
| GO:0042098 | T cell proliferation | 0.0001542 | 195 | 712 | 23 | 0.0323034 | 0.1179487 | GO:BP | ENSG00000196126,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000096996,ENSG00000134352,ENSG00000204472,ENSG00000147065,ENSG00000013725,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000123338,ENSG00000198851,ENSG00000242574,ENSG00000028137,ENSG00000147889,ENSG00000175104 |
| GO:0002263 | cell activation involved in immune response | 0.0001694 | 708 | 712 | 54 | 0.0758427 | 0.0762712 | GO:BP | ENSG00000172057,ENSG00000176083,ENSG00000073861,ENSG00000100321,ENSG00000135077,ENSG00000105639,ENSG00000137265,ENSG00000117984,ENSG00000136167,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000005844,ENSG00000196230,ENSG00000134765,ENSG00000137563,ENSG00000122223,ENSG00000213281,ENSG00000123131,ENSG00000064666,ENSG00000072958,ENSG00000166710,ENSG00000138071,ENSG00000131236,ENSG00000021355,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000100299,ENSG00000163131,ENSG00000131504,ENSG00000067560,ENSG00000172794,ENSG00000204642,ENSG00000168961,ENSG00000148175,ENSG00000174371,ENSG00000171302,ENSG00000147234,ENSG00000127666,ENSG00000139370,ENSG00000223496,ENSG00000116670,ENSG00000123338,ENSG00000140284,ENSG00000254087,ENSG00000160255,ENSG00000140319,ENSG00000127951,ENSG00000196839,ENSG00000148218,ENSG00000242574,ENSG00000028137,ENSG00000140575 |
| GO:0065003 | protein-containing complex assembly | 0.0001788 | 1770 | 712 | 108 | 0.1516854 | 0.0610169 | GO:BP | ENSG00000196126,ENSG00000248905,ENSG00000117724,ENSG00000179218,ENSG00000184357,ENSG00000154451,ENSG00000100427,ENSG00000155657,ENSG00000123485,ENSG00000231925,ENSG00000019582,ENSG00000198513,ENSG00000034510,ENSG00000069702,ENSG00000170315,ENSG00000166503,ENSG00000171848,ENSG00000117632,ENSG00000169252,ENSG00000160654,ENSG00000118193,ENSG00000112029,ENSG00000157216,ENSG00000136167,ENSG00000165617,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000100380,ENSG00000108518,ENSG00000116288,ENSG00000180644,ENSG00000103966,ENSG00000124575,ENSG00000105011,ENSG00000051341,ENSG00000187446,ENSG00000188312,ENSG00000011426,ENSG00000170312,ENSG00000105887,ENSG00000117394,ENSG00000215305,ENSG00000055332,ENSG00000242372,ENSG00000153094,ENSG00000119335,ENSG00000204472,ENSG00000163041,ENSG00000044574,ENSG00000130741,ENSG00000116030,ENSG00000132274,ENSG00000166710,ENSG00000111229,ENSG00000147065,ENSG00000204899,ENSG00000138071,ENSG00000156234,ENSG00000129534,ENSG00000115155,ENSG00000093009,ENSG00000084623,ENSG00000158869,ENSG00000136717,ENSG00000100385,ENSG00000131504,ENSG00000180574,ENSG00000198821,ENSG00000067560,ENSG00000075340,ENSG00000204256,ENSG00000165283,ENSG00000148175,ENSG00000132963,ENSG00000132182,ENSG00000160877,ENSG00000167286,ENSG00000042753,ENSG00000070831,ENSG00000079691,ENSG00000151239,ENSG00000197043,ENSG00000096968,ENSG00000165527,ENSG00000127666,ENSG00000184897,ENSG00000184640,ENSG00000123338,ENSG00000142867,ENSG00000109390,ENSG00000143740,ENSG00000198736,ENSG00000104738,ENSG00000119318,ENSG00000153044,ENSG00000137309,ENSG00000189306,ENSG00000197409,ENSG00000137312,ENSG00000198851,ENSG00000232838,ENSG00000148218,ENSG00000242574,ENSG00000111450,ENSG00000110218,ENSG00000113387 |
| GO:0002757 | immune response-activating signal transduction | 0.0001909 | 639 | 712 | 50 | 0.0702247 | 0.0782473 | GO:BP | ENSG00000004468,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000196735,ENSG00000203747,ENSG00000159216,ENSG00000155629,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000160654,ENSG00000137265,ENSG00000186470,ENSG00000117228,ENSG00000134321,ENSG00000204264,ENSG00000213281,ENSG00000211810,ENSG00000111229,ENSG00000138071,ENSG00000166598,ENSG00000158869,ENSG00000163131,ENSG00000198821,ENSG00000185507,ENSG00000115267,ENSG00000165283,ENSG00000167286,ENSG00000162676,ENSG00000070831,ENSG00000172936,ENSG00000075624,ENSG00000164164,ENSG00000127666,ENSG00000055163,ENSG00000123338,ENSG00000142867,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000101082,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000175104 |
| GO:0002822 | regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 0.0002069 | 144 | 712 | 19 | 0.0266854 | 0.1319444 | GO:BP | ENSG00000179344,ENSG00000073861,ENSG00000135077,ENSG00000105639,ENSG00000096996,ENSG00000232810,ENSG00000073008,ENSG00000134321,ENSG00000166710,ENSG00000158869,ENSG00000204642,ENSG00000122122,ENSG00000204592,ENSG00000153310,ENSG00000223496,ENSG00000116670,ENSG00000196839,ENSG00000028137,ENSG00000175104 |
| GO:0031347 | regulation of defense response | 0.0002186 | 807 | 712 | 59 | 0.0828652 | 0.0731103 | GO:BP | ENSG00000138496,ENSG00000117281,ENSG00000092010,ENSG00000125347,ENSG00000135077,ENSG00000154451,ENSG00000163840,ENSG00000089692,ENSG00000130164,ENSG00000115415,ENSG00000155629,ENSG00000100911,ENSG00000170315,ENSG00000137265,ENSG00000123609,ENSG00000096996,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000134352,ENSG00000116288,ENSG00000073008,ENSG00000134321,ENSG00000204264,ENSG00000077984,ENSG00000239713,ENSG00000213281,ENSG00000116030,ENSG00000185745,ENSG00000166598,ENSG00000196954,ENSG00000158869,ENSG00000013725,ENSG00000163131,ENSG00000197417,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000204592,ENSG00000162676,ENSG00000172936,ENSG00000096968,ENSG00000164164,ENSG00000128394,ENSG00000127666,ENSG00000132386,ENSG00000142867,ENSG00000138646,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000127951,ENSG00000137312,ENSG00000196839,ENSG00000028137,ENSG00000132256,ENSG00000175104,ENSG00000170485 |
| GO:0007049 | cell cycle | 0.0002237 | 1905 | 712 | 114 | 0.1601124 | 0.0598425 | GO:BP | ENSG00000148773,ENSG00000113721,ENSG00000092010,ENSG00000117724,ENSG00000125347,ENSG00000179218,ENSG00000165891,ENSG00000155657,ENSG00000123485,ENSG00000160014,ENSG00000100911,ENSG00000101057,ENSG00000170315,ENSG00000156970,ENSG00000171848,ENSG00000117632,ENSG00000196924,ENSG00000118193,ENSG00000112029,ENSG00000150093,ENSG00000138160,ENSG00000165617,ENSG00000111206,ENSG00000172757,ENSG00000111537,ENSG00000179051,ENSG00000232810,ENSG00000138180,ENSG00000126787,ENSG00000176890,ENSG00000133739,ENSG00000100749,ENSG00000132646,ENSG00000103769,ENSG00000196230,ENSG00000111602,ENSG00000175793,ENSG00000100918,ENSG00000143543,ENSG00000204264,ENSG00000011426,ENSG00000170312,ENSG00000185651,ENSG00000070018,ENSG00000092853,ENSG00000061337,ENSG00000153094,ENSG00000123416,ENSG00000065135,ENSG00000213445,ENSG00000148400,ENSG00000204472,ENSG00000089685,ENSG00000007968,ENSG00000166974,ENSG00000204899,ENSG00000166197,ENSG00000206127,ENSG00000131931,ENSG00000138071,ENSG00000118971,ENSG00000129534,ENSG00000093009,ENSG00000185650,ENSG00000143476,ENSG00000122952,ENSG00000143228,ENSG00000053254,ENSG00000136717,ENSG00000011485,ENSG00000067560,ENSG00000114166,ENSG00000213719,ENSG00000165304,ENSG00000133026,ENSG00000113810,ENSG00000131747,ENSG00000174371,ENSG00000189369,ENSG00000139579,ENSG00000162676,ENSG00000068489,ENSG00000106462,ENSG00000178996,ENSG00000176101,ENSG00000070831,ENSG00000152253,ENSG00000066279,ENSG00000075624,ENSG00000136824,ENSG00000165527,ENSG00000117155,ENSG00000109805,ENSG00000121579,ENSG00000116670,ENSG00000072571,ENSG00000184640,ENSG00000124688,ENSG00000114126,ENSG00000138646,ENSG00000049541,ENSG00000104738,ENSG00000172531,ENSG00000178691,ENSG00000153044,ENSG00000041357,ENSG00000125354,ENSG00000182628,ENSG00000136104,ENSG00000134690,ENSG00000147889,ENSG00000140575,ENSG00000137193,ENSG00000111859 |
| GO:0046637 | regulation of alpha-beta T cell differentiation | 0.0002709 | 63 | 712 | 12 | 0.0168539 | 0.1904762 | GO:BP | ENSG00000176083,ENSG00000073861,ENSG00000159216,ENSG00000105639,ENSG00000137265,ENSG00000096996,ENSG00000111537,ENSG00000067560,ENSG00000168961,ENSG00000122122,ENSG00000123338,ENSG00000196839 |
| GO:0070670 | response to interleukin-4 | 0.0003005 | 35 | 712 | 9 | 0.0126404 | 0.2571429 | GO:BP | ENSG00000105639,ENSG00000138795,ENSG00000123416,ENSG00000044574,ENSG00000165030,ENSG00000197417,ENSG00000079999,ENSG00000148218,ENSG00000147168 |
| GO:0070661 | leukocyte proliferation | 0.0003119 | 310 | 712 | 30 | 0.0421348 | 0.0967742 | GO:BP | ENSG00000004468,ENSG00000196126,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000096996,ENSG00000138795,ENSG00000134352,ENSG00000204472,ENSG00000147065,ENSG00000013725,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000172936,ENSG00000127666,ENSG00000123338,ENSG00000254087,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000028137,ENSG00000147889,ENSG00000175104 |
| GO:0046635 | positive regulation of alpha-beta T cell activation | 0.0003155 | 64 | 712 | 12 | 0.0168539 | 0.1875000 | GO:BP | ENSG00000179344,ENSG00000117281,ENSG00000159216,ENSG00000096996,ENSG00000111537,ENSG00000067560,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000123338,ENSG00000198851,ENSG00000196839 |
| GO:0070201 | regulation of establishment of protein localization | 0.0003528 | 802 | 712 | 58 | 0.0814607 | 0.0723192 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000135077,ENSG00000155657,ENSG00000182054,ENSG00000164111,ENSG00000196924,ENSG00000117984,ENSG00000136167,ENSG00000167461,ENSG00000110090,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000134308,ENSG00000204397,ENSG00000111640,ENSG00000103769,ENSG00000116288,ENSG00000134321,ENSG00000175793,ENSG00000187446,ENSG00000170312,ENSG00000122223,ENSG00000185651,ENSG00000117394,ENSG00000165949,ENSG00000204472,ENSG00000089685,ENSG00000118263,ENSG00000104805,ENSG00000180667,ENSG00000166197,ENSG00000021355,ENSG00000105220,ENSG00000133026,ENSG00000115267,ENSG00000168961,ENSG00000148175,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000111863,ENSG00000104765,ENSG00000070831,ENSG00000096968,ENSG00000170837,ENSG00000165527,ENSG00000102931,ENSG00000114126,ENSG00000254087,ENSG00000160255,ENSG00000028137,ENSG00000175104,ENSG00000110218 |
| GO:0030098 | lymphocyte differentiation | 0.0003634 | 361 | 712 | 33 | 0.0463483 | 0.0914127 | GO:BP | ENSG00000179344,ENSG00000176083,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000105639,ENSG00000160654,ENSG00000137265,ENSG00000150093,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000153563,ENSG00000134321,ENSG00000169230,ENSG00000166710,ENSG00000185650,ENSG00000158869,ENSG00000168421,ENSG00000184916,ENSG00000067560,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000167286,ENSG00000123338,ENSG00000127951,ENSG00000198851,ENSG00000196839,ENSG00000147889 |
| GO:0032729 | positive regulation of interferon-gamma production | 0.0003664 | 65 | 712 | 12 | 0.0168539 | 0.1846154 | GO:BP | ENSG00000117281,ENSG00000135077,ENSG00000223865,ENSG00000231389,ENSG00000096996,ENSG00000232810,ENSG00000122223,ENSG00000168961,ENSG00000122122,ENSG00000153310,ENSG00000198851,ENSG00000081985 |
| GO:0008104 | protein localization | 0.0003672 | 2923 | 712 | 160 | 0.2247191 | 0.0547383 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000138496,ENSG00000204267,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000117724,ENSG00000100321,ENSG00000179218,ENSG00000184357,ENSG00000135077,ENSG00000154451,ENSG00000100427,ENSG00000155657,ENSG00000163840,ENSG00000182054,ENSG00000019582,ENSG00000151502,ENSG00000160014,ENSG00000034510,ENSG00000091129,ENSG00000164111,ENSG00000170315,ENSG00000160654,ENSG00000196924,ENSG00000118193,ENSG00000117984,ENSG00000186470,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000125249,ENSG00000110090,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000232810,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000204397,ENSG00000111640,ENSG00000139626,ENSG00000103769,ENSG00000189319,ENSG00000005844,ENSG00000137474,ENSG00000116288,ENSG00000134321,ENSG00000175793,ENSG00000143742,ENSG00000131018,ENSG00000136274,ENSG00000187446,ENSG00000130402,ENSG00000011426,ENSG00000170312,ENSG00000122223,ENSG00000185651,ENSG00000117394,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000165949,ENSG00000185304,ENSG00000152969,ENSG00000215305,ENSG00000242372,ENSG00000153094,ENSG00000148400,ENSG00000157601,ENSG00000041353,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000044574,ENSG00000124587,ENSG00000116030,ENSG00000118263,ENSG00000072958,ENSG00000132274,ENSG00000104805,ENSG00000185745,ENSG00000147065,ENSG00000166974,ENSG00000204899,ENSG00000180667,ENSG00000166197,ENSG00000126016,ENSG00000253626,ENSG00000166598,ENSG00000157985,ENSG00000132661,ENSG00000021355,ENSG00000172803,ENSG00000105220,ENSG00000158869,ENSG00000131504,ENSG00000198821,ENSG00000213064,ENSG00000172794,ENSG00000133026,ENSG00000115267,ENSG00000168961,ENSG00000158882,ENSG00000172270,ENSG00000122877,ENSG00000148175,ENSG00000141736,ENSG00000204592,ENSG00000132182,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000139579,ENSG00000111863,ENSG00000106462,ENSG00000042753,ENSG00000178996,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000151239,ENSG00000075624,ENSG00000096968,ENSG00000079999,ENSG00000170837,ENSG00000165527,ENSG00000117155,ENSG00000162385,ENSG00000139370,ENSG00000127022,ENSG00000102931,ENSG00000184640,ENSG00000140450,ENSG00000148337,ENSG00000120709,ENSG00000114126,ENSG00000143740,ENSG00000129968,ENSG00000140284,ENSG00000125354,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000140319,ENSG00000155660,ENSG00000172667,ENSG00000137312,ENSG00000184575,ENSG00000028137,ENSG00000169223,ENSG00000132256,ENSG00000111481,ENSG00000139926,ENSG00000140575,ENSG00000111450,ENSG00000175104,ENSG00000110218 |
| GO:0030261 | chromosome condensation | 0.0003672 | 45 | 712 | 10 | 0.0140449 | 0.2222222 | GO:BP | ENSG00000184357,ENSG00000155657,ENSG00000124575,ENSG00000170312,ENSG00000163041,ENSG00000113810,ENSG00000131747,ENSG00000136824,ENSG00000109805,ENSG00000184897 |
| GO:0002460 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 0.0003759 | 362 | 712 | 33 | 0.0463483 | 0.0911602 | GO:BP | ENSG00000179344,ENSG00000196126,ENSG00000073861,ENSG00000135077,ENSG00000019582,ENSG00000105639,ENSG00000137265,ENSG00000186470,ENSG00000096996,ENSG00000138795,ENSG00000232810,ENSG00000153563,ENSG00000180644,ENSG00000073008,ENSG00000134321,ENSG00000166710,ENSG00000156234,ENSG00000158869,ENSG00000185507,ENSG00000204642,ENSG00000122122,ENSG00000204592,ENSG00000174371,ENSG00000153310,ENSG00000172936,ENSG00000223496,ENSG00000116670,ENSG00000142867,ENSG00000127951,ENSG00000101082,ENSG00000196839,ENSG00000028137,ENSG00000175104 |
| GO:0002274 | myeloid leukocyte activation | 0.0003766 | 657 | 712 | 50 | 0.0702247 | 0.0761035 | GO:BP | ENSG00000172057,ENSG00000100321,ENSG00000135077,ENSG00000019582,ENSG00000130164,ENSG00000137265,ENSG00000117984,ENSG00000111537,ENSG00000232810,ENSG00000005844,ENSG00000196230,ENSG00000134765,ENSG00000137563,ENSG00000077984,ENSG00000213281,ENSG00000123131,ENSG00000204472,ENSG00000064666,ENSG00000072958,ENSG00000166710,ENSG00000138071,ENSG00000131236,ENSG00000021355,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000168421,ENSG00000100299,ENSG00000163131,ENSG00000131504,ENSG00000067560,ENSG00000197417,ENSG00000172794,ENSG00000168961,ENSG00000148175,ENSG00000171302,ENSG00000147234,ENSG00000096968,ENSG00000127666,ENSG00000139370,ENSG00000123338,ENSG00000140284,ENSG00000254087,ENSG00000160255,ENSG00000140319,ENSG00000127951,ENSG00000148218,ENSG00000028137,ENSG00000140575,ENSG00000175104 |
| GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle | 0.0003956 | 28 | 712 | 8 | 0.0112360 | 0.2857143 | GO:BP | ENSG00000165891,ENSG00000171848,ENSG00000112029,ENSG00000176890,ENSG00000132646,ENSG00000093009,ENSG00000162676,ENSG00000114126 |
| GO:0042102 | positive regulation of T cell proliferation | 0.0003962 | 100 | 712 | 15 | 0.0210674 | 0.1500000 | GO:BP | ENSG00000135077,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000096996,ENSG00000134352,ENSG00000204472,ENSG00000013725,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000123338,ENSG00000198851,ENSG00000242574,ENSG00000175104 |
| GO:0033554 | cellular response to stress | 0.0004239 | 2105 | 712 | 122 | 0.1713483 | 0.0579572 | GO:BP | ENSG00000156587,ENSG00000138496,ENSG00000113721,ENSG00000092010,ENSG00000163599,ENSG00000109956,ENSG00000179218,ENSG00000115523,ENSG00000165891,ENSG00000134184,ENSG00000163840,ENSG00000019582,ENSG00000143870,ENSG00000100911,ENSG00000163029,ENSG00000170315,ENSG00000167004,ENSG00000112029,ENSG00000173848,ENSG00000165617,ENSG00000125249,ENSG00000111206,ENSG00000232810,ENSG00000204397,ENSG00000108179,ENSG00000132646,ENSG00000103148,ENSG00000116288,ENSG00000111602,ENSG00000175793,ENSG00000023572,ENSG00000100918,ENSG00000156463,ENSG00000204264,ENSG00000051341,ENSG00000170312,ENSG00000155846,ENSG00000164830,ENSG00000117394,ENSG00000131944,ENSG00000092853,ENSG00000055332,ENSG00000153094,ENSG00000213445,ENSG00000104687,ENSG00000148400,ENSG00000152256,ENSG00000204472,ENSG00000044574,ENSG00000133315,ENSG00000116030,ENSG00000166710,ENSG00000073803,ENSG00000163545,ENSG00000166454,ENSG00000180667,ENSG00000138071,ENSG00000166598,ENSG00000129675,ENSG00000196954,ENSG00000093009,ENSG00000185650,ENSG00000125871,ENSG00000074800,ENSG00000143476,ENSG00000053254,ENSG00000170881,ENSG00000139921,ENSG00000011485,ENSG00000067560,ENSG00000165304,ENSG00000134202,ENSG00000185507,ENSG00000168961,ENSG00000165283,ENSG00000131747,ENSG00000132182,ENSG00000174371,ENSG00000187608,ENSG00000139579,ENSG00000106462,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000178719,ENSG00000141030,ENSG00000054965,ENSG00000096968,ENSG00000176641,ENSG00000109674,ENSG00000079999,ENSG00000127022,ENSG00000138617,ENSG00000125648,ENSG00000116670,ENSG00000090520,ENSG00000128272,ENSG00000114126,ENSG00000126432,ENSG00000049541,ENSG00000104738,ENSG00000119318,ENSG00000172531,ENSG00000137309,ENSG00000041357,ENSG00000254087,ENSG00000213366,ENSG00000177076,ENSG00000155660,ENSG00000172667,ENSG00000137312,ENSG00000143321,ENSG00000136104,ENSG00000155090,ENSG00000135960,ENSG00000028137,ENSG00000178685,ENSG00000147889,ENSG00000175104,ENSG00000169554,ENSG00000170485,ENSG00000112759 |
| GO:0002291 | T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell | 0.0004565 | 9 | 712 | 5 | 0.0070225 | 0.5555556 | GO:BP | ENSG00000135077,ENSG00000005844,ENSG00000168961,ENSG00000127951,ENSG00000242574 |
| GO:0032623 | interleukin-2 production | 0.0004810 | 67 | 712 | 12 | 0.0168539 | 0.1791045 | GO:BP | ENSG00000073861,ENSG00000135077,ENSG00000089692,ENSG00000159216,ENSG00000137265,ENSG00000117228,ENSG00000158869,ENSG00000198821,ENSG00000122122,ENSG00000165283,ENSG00000198851,ENSG00000175104 |
| GO:0045581 | negative regulation of T cell differentiation | 0.0005280 | 47 | 712 | 10 | 0.0140449 | 0.2127660 | GO:BP | ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000105639,ENSG00000141736,ENSG00000127951,ENSG00000147889 |
| GO:0046632 | alpha-beta T cell differentiation | 0.0005556 | 103 | 712 | 15 | 0.0210674 | 0.1456311 | GO:BP | ENSG00000176083,ENSG00000073861,ENSG00000125347,ENSG00000159216,ENSG00000105639,ENSG00000137265,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000134321,ENSG00000067560,ENSG00000168961,ENSG00000122122,ENSG00000123338,ENSG00000196839 |
| GO:0007166 | cell surface receptor signaling pathway | 0.0005990 | 3197 | 712 | 171 | 0.2401685 | 0.0534876 | GO:BP | ENSG00000004468,ENSG00000119922,ENSG00000138496,ENSG00000113721,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000156886,ENSG00000163599,ENSG00000132530,ENSG00000125347,ENSG00000126709,ENSG00000160932,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000019582,ENSG00000117560,ENSG00000072135,ENSG00000203747,ENSG00000159216,ENSG00000115415,ENSG00000119917,ENSG00000186469,ENSG00000069702,ENSG00000100911,ENSG00000221866,ENSG00000205336,ENSG00000113368,ENSG00000177156,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000105639,ENSG00000117632,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000120057,ENSG00000127947,ENSG00000186470,ENSG00000150093,ENSG00000136167,ENSG00000211746,ENSG00000123609,ENSG00000096996,ENSG00000165617,ENSG00000172757,ENSG00000138795,ENSG00000211745,ENSG00000111537,ENSG00000179051,ENSG00000232810,ENSG00000183691,ENSG00000134539,ENSG00000117228,ENSG00000126787,ENSG00000211721,ENSG00000204397,ENSG00000100749,ENSG00000134352,ENSG00000139626,ENSG00000153563,ENSG00000108518,ENSG00000189319,ENSG00000005844,ENSG00000211747,ENSG00000185201,ENSG00000116288,ENSG00000135114,ENSG00000134321,ENSG00000169855,ENSG00000204264,ENSG00000237254,ENSG00000130402,ENSG00000185885,ENSG00000172116,ENSG00000070018,ENSG00000165949,ENSG00000153094,ENSG00000213281,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000171130,ENSG00000089685,ENSG00000044574,ENSG00000116030,ENSG00000064666,ENSG00000132274,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000159618,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000138071,ENSG00000166598,ENSG00000148730,ENSG00000156234,ENSG00000196954,ENSG00000111331,ENSG00000158869,ENSG00000013725,ENSG00000100385,ENSG00000125148,ENSG00000184916,ENSG00000198821,ENSG00000067560,ENSG00000213928,ENSG00000114166,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000115339,ENSG00000172270,ENSG00000165283,ENSG00000141736,ENSG00000204592,ENSG00000103994,ENSG00000167286,ENSG00000187608,ENSG00000157873,ENSG00000162676,ENSG00000042753,ENSG00000176101,ENSG00000070831,ENSG00000172936,ENSG00000179583,ENSG00000132670,ENSG00000066279,ENSG00000075624,ENSG00000096968,ENSG00000164164,ENSG00000168329,ENSG00000127666,ENSG00000127022,ENSG00000196072,ENSG00000102931,ENSG00000116670,ENSG00000055163,ENSG00000123338,ENSG00000142867,ENSG00000111335,ENSG00000172531,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000111796,ENSG00000101082,ENSG00000197409,ENSG00000131873,ENSG00000198851,ENSG00000196839,ENSG00000147168,ENSG00000135960,ENSG00000028137,ENSG00000132256,ENSG00000140575,ENSG00000137193,ENSG00000175104,ENSG00000169554,ENSG00000113387,ENSG00000111859,ENSG00000112759,ENSG00000081985 |
| GO:2000026 | regulation of multicellular organismal development | 0.0006265 | 2210 | 712 | 126 | 0.1769663 | 0.0570136 | GO:BP | ENSG00000004468,ENSG00000113721,ENSG00000176083,ENSG00000117281,ENSG00000183688,ENSG00000092010,ENSG00000073861,ENSG00000163599,ENSG00000117724,ENSG00000125347,ENSG00000180739,ENSG00000179218,ENSG00000135077,ENSG00000089692,ENSG00000182054,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000159216,ENSG00000173482,ENSG00000130164,ENSG00000115415,ENSG00000069702,ENSG00000091129,ENSG00000100911,ENSG00000221866,ENSG00000205336,ENSG00000105639,ENSG00000169252,ENSG00000196924,ENSG00000137265,ENSG00000118193,ENSG00000112029,ENSG00000120057,ENSG00000150093,ENSG00000096996,ENSG00000165617,ENSG00000125249,ENSG00000173114,ENSG00000133321,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000112139,ENSG00000232810,ENSG00000183691,ENSG00000183734,ENSG00000134352,ENSG00000103769,ENSG00000108518,ENSG00000175793,ENSG00000169855,ENSG00000204264,ENSG00000077984,ENSG00000170312,ENSG00000105887,ENSG00000155846,ENSG00000141576,ENSG00000139182,ENSG00000171603,ENSG00000061337,ENSG00000055332,ENSG00000242372,ENSG00000169230,ENSG00000148400,ENSG00000163041,ENSG00000044574,ENSG00000007968,ENSG00000118263,ENSG00000166710,ENSG00000073803,ENSG00000163823,ENSG00000126016,ENSG00000138071,ENSG00000111348,ENSG00000156234,ENSG00000185650,ENSG00000136717,ENSG00000071994,ENSG00000168421,ENSG00000067560,ENSG00000132932,ENSG00000127952,ENSG00000114166,ENSG00000185507,ENSG00000168961,ENSG00000122122,ENSG00000171617,ENSG00000141736,ENSG00000213626,ENSG00000187608,ENSG00000162676,ENSG00000106462,ENSG00000042753,ENSG00000070831,ENSG00000124920,ENSG00000151239,ENSG00000066279,ENSG00000176542,ENSG00000079999,ENSG00000165527,ENSG00000168329,ENSG00000105697,ENSG00000223496,ENSG00000116670,ENSG00000132386,ENSG00000123338,ENSG00000171943,ENSG00000128272,ENSG00000111335,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000091127,ENSG00000127951,ENSG00000197409,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000155090,ENSG00000028137,ENSG00000147889,ENSG00000140575,ENSG00000137193,ENSG00000175104,ENSG00000169554 |
| GO:0050790 | regulation of catalytic activity | 0.0006437 | 2385 | 712 | 134 | 0.1882022 | 0.0561845 | GO:BP | ENSG00000138496,ENSG00000113721,ENSG00000198826,ENSG00000092010,ENSG00000126709,ENSG00000147459,ENSG00000155657,ENSG00000163840,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000160014,ENSG00000100911,ENSG00000221866,ENSG00000164111,ENSG00000170315,ENSG00000169252,ENSG00000146674,ENSG00000118193,ENSG00000112029,ENSG00000117984,ENSG00000150093,ENSG00000173848,ENSG00000133321,ENSG00000138795,ENSG00000111537,ENSG00000179051,ENSG00000232810,ENSG00000204397,ENSG00000108179,ENSG00000111640,ENSG00000132646,ENSG00000108518,ENSG00000103148,ENSG00000116288,ENSG00000171596,ENSG00000213390,ENSG00000135114,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000156463,ENSG00000143543,ENSG00000204264,ENSG00000188191,ENSG00000077984,ENSG00000187446,ENSG00000071205,ENSG00000170312,ENSG00000155846,ENSG00000163359,ENSG00000185651,ENSG00000070018,ENSG00000185304,ENSG00000092853,ENSG00000055332,ENSG00000169230,ENSG00000153094,ENSG00000065135,ENSG00000213445,ENSG00000159200,ENSG00000119335,ENSG00000148400,ENSG00000089127,ENSG00000152256,ENSG00000089685,ENSG00000073803,ENSG00000185745,ENSG00000166974,ENSG00000154001,ENSG00000126016,ENSG00000073910,ENSG00000166598,ENSG00000129007,ENSG00000131236,ENSG00000157985,ENSG00000111348,ENSG00000156234,ENSG00000129675,ENSG00000118971,ENSG00000021355,ENSG00000196954,ENSG00000111331,ENSG00000105220,ENSG00000181467,ENSG00000145649,ENSG00000136717,ENSG00000071994,ENSG00000168421,ENSG00000134909,ENSG00000067560,ENSG00000125944,ENSG00000127952,ENSG00000114166,ENSG00000087302,ENSG00000168961,ENSG00000141736,ENSG00000162676,ENSG00000106462,ENSG00000178996,ENSG00000070831,ENSG00000164088,ENSG00000166035,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000162104,ENSG00000148908,ENSG00000138617,ENSG00000102931,ENSG00000116670,ENSG00000055163,ENSG00000090520,ENSG00000132386,ENSG00000123338,ENSG00000140450,ENSG00000142867,ENSG00000111335,ENSG00000126432,ENSG00000138646,ENSG00000049541,ENSG00000254087,ENSG00000160255,ENSG00000143248,ENSG00000177076,ENSG00000101082,ENSG00000150756,ENSG00000147889,ENSG00000140575,ENSG00000155096,ENSG00000175104,ENSG00000169554,ENSG00000127084,ENSG00000111859 |
| GO:0050793 | regulation of developmental process | 0.0006437 | 2779 | 712 | 152 | 0.2134831 | 0.0546959 | GO:BP | ENSG00000004468,ENSG00000113721,ENSG00000176083,ENSG00000117281,ENSG00000183688,ENSG00000007402,ENSG00000092010,ENSG00000073861,ENSG00000163599,ENSG00000117724,ENSG00000125347,ENSG00000180739,ENSG00000179218,ENSG00000135077,ENSG00000147459,ENSG00000089692,ENSG00000182054,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000159216,ENSG00000173482,ENSG00000130164,ENSG00000115415,ENSG00000069702,ENSG00000091129,ENSG00000100911,ENSG00000221866,ENSG00000205336,ENSG00000105639,ENSG00000169252,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000118193,ENSG00000112029,ENSG00000120057,ENSG00000157216,ENSG00000150093,ENSG00000096996,ENSG00000165617,ENSG00000125249,ENSG00000173114,ENSG00000111206,ENSG00000133321,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000112139,ENSG00000232810,ENSG00000183691,ENSG00000117228,ENSG00000176293,ENSG00000183734,ENSG00000134352,ENSG00000103769,ENSG00000108518,ENSG00000175793,ENSG00000169855,ENSG00000204264,ENSG00000077984,ENSG00000130402,ENSG00000170312,ENSG00000105887,ENSG00000155846,ENSG00000185885,ENSG00000141576,ENSG00000139182,ENSG00000171603,ENSG00000061337,ENSG00000055332,ENSG00000242372,ENSG00000169230,ENSG00000153094,ENSG00000159200,ENSG00000148400,ENSG00000163041,ENSG00000044574,ENSG00000007968,ENSG00000118263,ENSG00000166710,ENSG00000073803,ENSG00000163823,ENSG00000147065,ENSG00000128578,ENSG00000126016,ENSG00000138071,ENSG00000111348,ENSG00000156234,ENSG00000185650,ENSG00000136717,ENSG00000071994,ENSG00000168421,ENSG00000130005,ENSG00000131504,ENSG00000067560,ENSG00000132932,ENSG00000127952,ENSG00000114166,ENSG00000213719,ENSG00000133026,ENSG00000185507,ENSG00000168961,ENSG00000122122,ENSG00000171617,ENSG00000141736,ENSG00000213626,ENSG00000187608,ENSG00000162676,ENSG00000106462,ENSG00000042753,ENSG00000070831,ENSG00000079691,ENSG00000124920,ENSG00000151239,ENSG00000066279,ENSG00000096968,ENSG00000176542,ENSG00000079999,ENSG00000165527,ENSG00000168329,ENSG00000105697,ENSG00000223496,ENSG00000116670,ENSG00000132386,ENSG00000123338,ENSG00000171943,ENSG00000128272,ENSG00000111335,ENSG00000178691,ENSG00000137309,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000091127,ENSG00000127951,ENSG00000197409,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000155090,ENSG00000028137,ENSG00000147889,ENSG00000140575,ENSG00000137193,ENSG00000175104,ENSG00000169554,ENSG00000127084,ENSG00000166794,ENSG00000111859 |
| GO:0033036 | macromolecule localization | 0.0006437 | 3292 | 712 | 175 | 0.2457865 | 0.0531592 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000138496,ENSG00000204267,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000117724,ENSG00000221963,ENSG00000100321,ENSG00000179218,ENSG00000184357,ENSG00000135077,ENSG00000154451,ENSG00000100427,ENSG00000155657,ENSG00000163840,ENSG00000182054,ENSG00000019582,ENSG00000151502,ENSG00000160014,ENSG00000034510,ENSG00000130164,ENSG00000091129,ENSG00000164111,ENSG00000170315,ENSG00000160654,ENSG00000196924,ENSG00000118193,ENSG00000117984,ENSG00000186470,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000125249,ENSG00000110090,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000232810,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000204397,ENSG00000111640,ENSG00000139626,ENSG00000103769,ENSG00000128335,ENSG00000128284,ENSG00000189319,ENSG00000005844,ENSG00000137474,ENSG00000116288,ENSG00000103202,ENSG00000134321,ENSG00000175793,ENSG00000143742,ENSG00000131018,ENSG00000136274,ENSG00000187446,ENSG00000130402,ENSG00000011426,ENSG00000170312,ENSG00000122223,ENSG00000185651,ENSG00000117394,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000165949,ENSG00000185304,ENSG00000152969,ENSG00000215305,ENSG00000242372,ENSG00000169230,ENSG00000153094,ENSG00000148400,ENSG00000157601,ENSG00000164211,ENSG00000041353,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000044574,ENSG00000124587,ENSG00000116030,ENSG00000118263,ENSG00000072958,ENSG00000132274,ENSG00000104805,ENSG00000185745,ENSG00000147065,ENSG00000166974,ENSG00000204899,ENSG00000180667,ENSG00000166197,ENSG00000126016,ENSG00000253626,ENSG00000166598,ENSG00000157985,ENSG00000132661,ENSG00000100342,ENSG00000021355,ENSG00000185650,ENSG00000172803,ENSG00000105220,ENSG00000158869,ENSG00000131504,ENSG00000198821,ENSG00000132932,ENSG00000213064,ENSG00000172794,ENSG00000133026,ENSG00000115267,ENSG00000087302,ENSG00000168961,ENSG00000158882,ENSG00000172270,ENSG00000122877,ENSG00000165283,ENSG00000172795,ENSG00000148175,ENSG00000141736,ENSG00000204592,ENSG00000132182,ENSG00000187608,ENSG00000157873,ENSG00000021762,ENSG00000198843,ENSG00000139579,ENSG00000111863,ENSG00000106462,ENSG00000042753,ENSG00000178996,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000151239,ENSG00000166035,ENSG00000075624,ENSG00000096968,ENSG00000079999,ENSG00000170837,ENSG00000165527,ENSG00000117155,ENSG00000162385,ENSG00000139370,ENSG00000127022,ENSG00000102931,ENSG00000184640,ENSG00000140450,ENSG00000148337,ENSG00000120709,ENSG00000114126,ENSG00000143740,ENSG00000129968,ENSG00000140284,ENSG00000125354,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000140319,ENSG00000155660,ENSG00000172667,ENSG00000137312,ENSG00000184575,ENSG00000028137,ENSG00000169223,ENSG00000132256,ENSG00000111481,ENSG00000139926,ENSG00000140575,ENSG00000111450,ENSG00000175104,ENSG00000110218 |
| GO:0023052 | signaling | 0.0006469 | 6772 | 712 | 323 | 0.4536517 | 0.0476964 | GO:BP | ENSG00000137441,ENSG00000100453,ENSG00000004468,ENSG00000119922,ENSG00000100450,ENSG00000138496,ENSG00000113721,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000198826,ENSG00000092010,ENSG00000156886,ENSG00000163599,ENSG00000132530,ENSG00000125347,ENSG00000108679,ENSG00000100321,ENSG00000180739,ENSG00000179218,ENSG00000002834,ENSG00000126709,ENSG00000135077,ENSG00000160932,ENSG00000165891,ENSG00000147459,ENSG00000155657,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000072135,ENSG00000203747,ENSG00000159216,ENSG00000160014,ENSG00000173482,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000155629,ENSG00000186469,ENSG00000069702,ENSG00000091129,ENSG00000100911,ENSG00000221866,ENSG00000205336,ENSG00000164111,ENSG00000113368,ENSG00000177156,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000166503,ENSG00000105639,ENSG00000117632,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000118193,ENSG00000120057,ENSG00000127947,ENSG00000186470,ENSG00000150093,ENSG00000136167,ENSG00000211746,ENSG00000167461,ENSG00000105409,ENSG00000123609,ENSG00000173848,ENSG00000096996,ENSG00000165617,ENSG00000125249,ENSG00000111206,ENSG00000172757,ENSG00000138795,ENSG00000211745,ENSG00000110090,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000189430,ENSG00000232810,ENSG00000183691,ENSG00000134539,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000126787,ENSG00000211721,ENSG00000204397,ENSG00000100749,ENSG00000108179,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000153563,ENSG00000103769,ENSG00000108518,ENSG00000128284,ENSG00000131171,ENSG00000189319,ENSG00000005844,ENSG00000130592,ENSG00000103148,ENSG00000211747,ENSG00000185201,ENSG00000116288,ENSG00000171596,ENSG00000213390,ENSG00000135114,ENSG00000134321,ENSG00000175793,ENSG00000169855,ENSG00000023572,ENSG00000152465,ENSG00000156463,ENSG00000204264,ENSG00000188191,ENSG00000114978,ENSG00000237254,ENSG00000187446,ENSG00000130402,ENSG00000071205,ENSG00000170312,ENSG00000155846,ENSG00000122223,ENSG00000185885,ENSG00000117394,ENSG00000172116,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000165949,ENSG00000061337,ENSG00000055332,ENSG00000169230,ENSG00000153094,ENSG00000065135,ENSG00000213445,ENSG00000213281,ENSG00000123131,ENSG00000159200,ENSG00000148400,ENSG00000157601,ENSG00000041353,ENSG00000089127,ENSG00000152256,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000121297,ENSG00000044574,ENSG00000171246,ENSG00000116030,ENSG00000007968,ENSG00000118263,ENSG00000064666,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000073803,ENSG00000159618,ENSG00000104805,ENSG00000163545,ENSG00000152778,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000166974,ENSG00000180667,ENSG00000154001,ENSG00000126016,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000129007,ENSG00000131236,ENSG00000110448,ENSG00000111348,ENSG00000148730,ENSG00000156234,ENSG00000129675,ENSG00000196954,ENSG00000183475,ENSG00000115155,ENSG00000185650,ENSG00000100605,ENSG00000111331,ENSG00000074800,ENSG00000143476,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000136717,ENSG00000116983,ENSG00000168421,ENSG00000013725,ENSG00000134909,ENSG00000163131,ENSG00000100385,ENSG00000125148,ENSG00000184916,ENSG00000198821,ENSG00000011485,ENSG00000067560,ENSG00000213928,ENSG00000127952,ENSG00000114166,ENSG00000189283,ENSG00000213719,ENSG00000165304,ENSG00000172794,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000006625,ENSG00000168961,ENSG00000115339,ENSG00000115902,ENSG00000172270,ENSG00000122877,ENSG00000165283,ENSG00000141736,ENSG00000204592,ENSG00000103994,ENSG00000158321,ENSG00000174371,ENSG00000213626,ENSG00000167286,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000103495,ENSG00000162676,ENSG00000111863,ENSG00000106462,ENSG00000042753,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000101079,ENSG00000179583,ENSG00000171302,ENSG00000178719,ENSG00000141030,ENSG00000197043,ENSG00000132670,ENSG00000066279,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000176641,ENSG00000170837,ENSG00000165527,ENSG00000117155,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000105697,ENSG00000127022,ENSG00000197956,ENSG00000148908,ENSG00000196072,ENSG00000138617,ENSG00000102931,ENSG00000116670,ENSG00000055163,ENSG00000090520,ENSG00000256436,ENSG00000123338,ENSG00000128272,ENSG00000142867,ENSG00000111335,ENSG00000114126,ENSG00000143740,ENSG00000049541,ENSG00000172531,ENSG00000041357,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000143248,ENSG00000213366,ENSG00000111796,ENSG00000177076,ENSG00000101082,ENSG00000197409,ENSG00000131873,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000143321,ENSG00000155090,ENSG00000147168,ENSG00000177674,ENSG00000135960,ENSG00000028137,ENSG00000160753,ENSG00000132256,ENSG00000147889,ENSG00000140575,ENSG00000137193,ENSG00000160404,ENSG00000111450,ENSG00000175104,ENSG00000110218,ENSG00000169554,ENSG00000127084,ENSG00000113387,ENSG00000111859,ENSG00000112759,ENSG00000081985 |
| GO:0045184 | establishment of protein localization | 0.0006563 | 2235 | 712 | 127 | 0.1783708 | 0.0568233 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000204267,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000117724,ENSG00000100321,ENSG00000179218,ENSG00000184357,ENSG00000135077,ENSG00000154451,ENSG00000100427,ENSG00000155657,ENSG00000163840,ENSG00000182054,ENSG00000019582,ENSG00000151502,ENSG00000160014,ENSG00000164111,ENSG00000170315,ENSG00000160654,ENSG00000196924,ENSG00000118193,ENSG00000117984,ENSG00000186470,ENSG00000136167,ENSG00000167461,ENSG00000125249,ENSG00000110090,ENSG00000111537,ENSG00000179051,ENSG00000232810,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000204397,ENSG00000111640,ENSG00000103769,ENSG00000189319,ENSG00000137474,ENSG00000116288,ENSG00000134321,ENSG00000175793,ENSG00000143742,ENSG00000136274,ENSG00000187446,ENSG00000130402,ENSG00000170312,ENSG00000122223,ENSG00000185651,ENSG00000117394,ENSG00000171603,ENSG00000165949,ENSG00000185304,ENSG00000152969,ENSG00000215305,ENSG00000242372,ENSG00000153094,ENSG00000148400,ENSG00000157601,ENSG00000041353,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000044574,ENSG00000124587,ENSG00000118263,ENSG00000072958,ENSG00000104805,ENSG00000185745,ENSG00000180667,ENSG00000166197,ENSG00000253626,ENSG00000166598,ENSG00000157985,ENSG00000132661,ENSG00000021355,ENSG00000172803,ENSG00000105220,ENSG00000213064,ENSG00000172794,ENSG00000133026,ENSG00000115267,ENSG00000168961,ENSG00000158882,ENSG00000122877,ENSG00000148175,ENSG00000141736,ENSG00000204592,ENSG00000132182,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000139579,ENSG00000111863,ENSG00000042753,ENSG00000178996,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000096968,ENSG00000170837,ENSG00000165527,ENSG00000117155,ENSG00000162385,ENSG00000139370,ENSG00000127022,ENSG00000102931,ENSG00000140450,ENSG00000120709,ENSG00000114126,ENSG00000143740,ENSG00000140284,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000140319,ENSG00000155660,ENSG00000172667,ENSG00000184575,ENSG00000028137,ENSG00000169223,ENSG00000111481,ENSG00000111450,ENSG00000175104,ENSG00000110218 |
| GO:0002764 | immune response-regulating signaling pathway | 0.0006604 | 673 | 712 | 50 | 0.0702247 | 0.0742942 | GO:BP | ENSG00000004468,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000196735,ENSG00000203747,ENSG00000159216,ENSG00000155629,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000160654,ENSG00000137265,ENSG00000186470,ENSG00000117228,ENSG00000134321,ENSG00000204264,ENSG00000213281,ENSG00000211810,ENSG00000111229,ENSG00000138071,ENSG00000166598,ENSG00000158869,ENSG00000163131,ENSG00000198821,ENSG00000185507,ENSG00000115267,ENSG00000165283,ENSG00000167286,ENSG00000162676,ENSG00000070831,ENSG00000172936,ENSG00000075624,ENSG00000164164,ENSG00000127666,ENSG00000055163,ENSG00000123338,ENSG00000142867,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000101082,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000175104 |
| GO:0045089 | positive regulation of innate immune response | 0.0006702 | 374 | 712 | 33 | 0.0463483 | 0.0882353 | GO:BP | ENSG00000138496,ENSG00000117281,ENSG00000092010,ENSG00000125347,ENSG00000135077,ENSG00000154451,ENSG00000089692,ENSG00000155629,ENSG00000100911,ENSG00000170315,ENSG00000137265,ENSG00000073008,ENSG00000134321,ENSG00000204264,ENSG00000213281,ENSG00000166598,ENSG00000158869,ENSG00000163131,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000204592,ENSG00000162676,ENSG00000172936,ENSG00000164164,ENSG00000127666,ENSG00000142867,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000137312,ENSG00000132256,ENSG00000175104 |
| GO:0090087 | regulation of peptide transport | 0.0006833 | 786 | 712 | 56 | 0.0786517 | 0.0712468 | GO:BP | ENSG00000004468,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000135077,ENSG00000155657,ENSG00000182054,ENSG00000019582,ENSG00000164111,ENSG00000196924,ENSG00000136167,ENSG00000167461,ENSG00000110090,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000204397,ENSG00000111640,ENSG00000103769,ENSG00000116288,ENSG00000134321,ENSG00000175793,ENSG00000187446,ENSG00000170312,ENSG00000122223,ENSG00000185651,ENSG00000117394,ENSG00000165949,ENSG00000204472,ENSG00000089685,ENSG00000118263,ENSG00000104805,ENSG00000180667,ENSG00000166197,ENSG00000021355,ENSG00000105220,ENSG00000133026,ENSG00000115267,ENSG00000168961,ENSG00000148175,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000198843,ENSG00000111863,ENSG00000104765,ENSG00000070831,ENSG00000096968,ENSG00000170837,ENSG00000165527,ENSG00000102931,ENSG00000254087,ENSG00000160255,ENSG00000028137,ENSG00000175104,ENSG00000110218 |
| GO:0032880 | regulation of protein localization | 0.0006888 | 1076 | 712 | 71 | 0.0997191 | 0.0659851 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000138496,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000135077,ENSG00000155657,ENSG00000163840,ENSG00000182054,ENSG00000164111,ENSG00000196924,ENSG00000117984,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000110090,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000134308,ENSG00000204397,ENSG00000111640,ENSG00000103769,ENSG00000116288,ENSG00000134321,ENSG00000175793,ENSG00000187446,ENSG00000170312,ENSG00000122223,ENSG00000185651,ENSG00000117394,ENSG00000139182,ENSG00000165949,ENSG00000204472,ENSG00000089685,ENSG00000116030,ENSG00000118263,ENSG00000132274,ENSG00000104805,ENSG00000147065,ENSG00000180667,ENSG00000166197,ENSG00000021355,ENSG00000105220,ENSG00000158869,ENSG00000198821,ENSG00000133026,ENSG00000115267,ENSG00000168961,ENSG00000148175,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000111863,ENSG00000104765,ENSG00000070831,ENSG00000075624,ENSG00000096968,ENSG00000170837,ENSG00000165527,ENSG00000102931,ENSG00000114126,ENSG00000129968,ENSG00000254087,ENSG00000160255,ENSG00000028137,ENSG00000132256,ENSG00000140575,ENSG00000175104,ENSG00000110218 |
| GO:0002521 | leukocyte differentiation | 0.0007241 | 531 | 712 | 42 | 0.0589888 | 0.0790960 | GO:BP | ENSG00000179344,ENSG00000176083,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000105639,ENSG00000160654,ENSG00000137265,ENSG00000150093,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000153563,ENSG00000134321,ENSG00000160219,ENSG00000155846,ENSG00000169230,ENSG00000166710,ENSG00000163823,ENSG00000185650,ENSG00000158869,ENSG00000168421,ENSG00000184916,ENSG00000067560,ENSG00000185507,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000167286,ENSG00000070831,ENSG00000123338,ENSG00000254087,ENSG00000127951,ENSG00000198851,ENSG00000196839,ENSG00000155090,ENSG00000147889,ENSG00000175104 |
| GO:0034975 | protein folding in endoplasmic reticulum | 0.0008084 | 10 | 712 | 5 | 0.0070225 | 0.5000000 | GO:BP | ENSG00000179218,ENSG00000167004,ENSG00000044574,ENSG00000166598,ENSG00000127022 |
| GO:0048519 | negative regulation of biological process | 0.0008125 | 5681 | 712 | 277 | 0.3890449 | 0.0487590 | GO:BP | ENSG00000172057,ENSG00000100453,ENSG00000004468,ENSG00000156587,ENSG00000138496,ENSG00000113721,ENSG00000117281,ENSG00000196126,ENSG00000183688,ENSG00000229474,ENSG00000092010,ENSG00000072110,ENSG00000073861,ENSG00000163599,ENSG00000117724,ENSG00000125347,ENSG00000179218,ENSG00000126709,ENSG00000175274,ENSG00000184357,ENSG00000135077,ENSG00000165891,ENSG00000147459,ENSG00000163840,ENSG00000089692,ENSG00000182054,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000072135,ENSG00000159216,ENSG00000160014,ENSG00000034510,ENSG00000173482,ENSG00000130164,ENSG00000115415,ENSG00000119917,ENSG00000069702,ENSG00000100911,ENSG00000221866,ENSG00000205336,ENSG00000164111,ENSG00000170315,ENSG00000166503,ENSG00000156970,ENSG00000171848,ENSG00000105639,ENSG00000117632,ENSG00000142089,ENSG00000169252,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000175550,ENSG00000118193,ENSG00000112029,ENSG00000120057,ENSG00000127947,ENSG00000150093,ENSG00000123609,ENSG00000165617,ENSG00000125249,ENSG00000111206,ENSG00000133321,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000232810,ENSG00000183691,ENSG00000117228,ENSG00000134308,ENSG00000176890,ENSG00000204397,ENSG00000108179,ENSG00000111640,ENSG00000183734,ENSG00000134352,ENSG00000132646,ENSG00000100380,ENSG00000108518,ENSG00000183741,ENSG00000103148,ENSG00000185201,ENSG00000116288,ENSG00000111602,ENSG00000135114,ENSG00000134321,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000124575,ENSG00000156463,ENSG00000204264,ENSG00000143742,ENSG00000051341,ENSG00000188191,ENSG00000077984,ENSG00000187446,ENSG00000130402,ENSG00000071205,ENSG00000170312,ENSG00000105887,ENSG00000155846,ENSG00000185885,ENSG00000163359,ENSG00000164830,ENSG00000141576,ENSG00000070018,ENSG00000165949,ENSG00000092853,ENSG00000061337,ENSG00000055332,ENSG00000239713,ENSG00000242372,ENSG00000169230,ENSG00000065135,ENSG00000213445,ENSG00000123131,ENSG00000159200,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000167723,ENSG00000152256,ENSG00000204472,ENSG00000089685,ENSG00000121297,ENSG00000163041,ENSG00000044574,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000132274,ENSG00000166710,ENSG00000179632,ENSG00000163545,ENSG00000152778,ENSG00000185745,ENSG00000163823,ENSG00000180667,ENSG00000126016,ENSG00000073910,ENSG00000131931,ENSG00000166598,ENSG00000111348,ENSG00000148730,ENSG00000156234,ENSG00000118971,ENSG00000021355,ENSG00000093009,ENSG00000185650,ENSG00000111331,ENSG00000074800,ENSG00000143476,ENSG00000122952,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000196449,ENSG00000053254,ENSG00000145649,ENSG00000136717,ENSG00000168421,ENSG00000158006,ENSG00000170881,ENSG00000100385,ENSG00000125148,ENSG00000131504,ENSG00000184916,ENSG00000011485,ENSG00000067560,ENSG00000132932,ENSG00000125944,ENSG00000127952,ENSG00000114166,ENSG00000189283,ENSG00000075340,ENSG00000185507,ENSG00000100298,ENSG00000204642,ENSG00000115267,ENSG00000087302,ENSG00000168961,ENSG00000172795,ENSG00000131747,ENSG00000171617,ENSG00000141736,ENSG00000162702,ENSG00000204592,ENSG00000132182,ENSG00000160877,ENSG00000213626,ENSG00000187608,ENSG00000157873,ENSG00000189369,ENSG00000139579,ENSG00000103495,ENSG00000162676,ENSG00000111863,ENSG00000068489,ENSG00000106462,ENSG00000104765,ENSG00000070831,ENSG00000079691,ENSG00000172936,ENSG00000170860,ENSG00000171169,ENSG00000151239,ENSG00000101079,ENSG00000179583,ENSG00000178719,ENSG00000197043,ENSG00000189266,ENSG00000066279,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000176542,ENSG00000128394,ENSG00000176641,ENSG00000079999,ENSG00000165527,ENSG00000162385,ENSG00000168329,ENSG00000127666,ENSG00000105697,ENSG00000223496,ENSG00000148908,ENSG00000138617,ENSG00000184897,ENSG00000116670,ENSG00000132386,ENSG00000123338,ENSG00000171943,ENSG00000128272,ENSG00000124688,ENSG00000142867,ENSG00000111335,ENSG00000114126,ENSG00000126432,ENSG00000138646,ENSG00000178691,ENSG00000129968,ENSG00000137309,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000143248,ENSG00000091127,ENSG00000213366,ENSG00000177076,ENSG00000127951,ENSG00000101082,ENSG00000197409,ENSG00000131873,ENSG00000198851,ENSG00000196839,ENSG00000143321,ENSG00000136104,ENSG00000155090,ENSG00000148218,ENSG00000028137,ENSG00000178685,ENSG00000132256,ENSG00000147889,ENSG00000140575,ENSG00000137193,ENSG00000155096,ENSG00000175104,ENSG00000169554,ENSG00000113387,ENSG00000170485 |
| GO:0065009 | regulation of molecular function | 0.0008125 | 3061 | 712 | 164 | 0.2303371 | 0.0535773 | GO:BP | ENSG00000119922,ENSG00000138496,ENSG00000113721,ENSG00000198826,ENSG00000092010,ENSG00000126709,ENSG00000135077,ENSG00000160932,ENSG00000147459,ENSG00000155657,ENSG00000163840,ENSG00000163421,ENSG00000123485,ENSG00000019582,ENSG00000117560,ENSG00000160014,ENSG00000069702,ENSG00000100911,ENSG00000221866,ENSG00000164111,ENSG00000170315,ENSG00000117632,ENSG00000169252,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000118193,ENSG00000112029,ENSG00000120057,ENSG00000117984,ENSG00000150093,ENSG00000173848,ENSG00000165617,ENSG00000133321,ENSG00000138795,ENSG00000111537,ENSG00000179051,ENSG00000232810,ENSG00000183691,ENSG00000204397,ENSG00000108179,ENSG00000111640,ENSG00000132646,ENSG00000108518,ENSG00000103148,ENSG00000116288,ENSG00000171596,ENSG00000213390,ENSG00000135114,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000156463,ENSG00000143543,ENSG00000204264,ENSG00000188191,ENSG00000077984,ENSG00000187446,ENSG00000130402,ENSG00000071205,ENSG00000170312,ENSG00000105887,ENSG00000155846,ENSG00000163359,ENSG00000185651,ENSG00000070018,ENSG00000185304,ENSG00000092853,ENSG00000055332,ENSG00000169230,ENSG00000153094,ENSG00000065135,ENSG00000213445,ENSG00000159200,ENSG00000119335,ENSG00000148400,ENSG00000089127,ENSG00000152256,ENSG00000089685,ENSG00000171246,ENSG00000116030,ENSG00000132274,ENSG00000166710,ENSG00000073803,ENSG00000185745,ENSG00000166974,ENSG00000154001,ENSG00000126016,ENSG00000073910,ENSG00000166598,ENSG00000129007,ENSG00000131236,ENSG00000157985,ENSG00000111348,ENSG00000156234,ENSG00000129675,ENSG00000118971,ENSG00000021355,ENSG00000196954,ENSG00000111331,ENSG00000105220,ENSG00000181467,ENSG00000145649,ENSG00000136717,ENSG00000071994,ENSG00000168421,ENSG00000134909,ENSG00000163131,ENSG00000067560,ENSG00000125944,ENSG00000127952,ENSG00000114166,ENSG00000075340,ENSG00000087302,ENSG00000168961,ENSG00000148175,ENSG00000141736,ENSG00000162676,ENSG00000106462,ENSG00000178996,ENSG00000070831,ENSG00000172936,ENSG00000164088,ENSG00000166035,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000079999,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000148908,ENSG00000138617,ENSG00000102931,ENSG00000116670,ENSG00000055163,ENSG00000090520,ENSG00000132386,ENSG00000123338,ENSG00000140450,ENSG00000142867,ENSG00000111335,ENSG00000126432,ENSG00000138646,ENSG00000049541,ENSG00000172531,ENSG00000254087,ENSG00000160255,ENSG00000143248,ENSG00000213366,ENSG00000177076,ENSG00000101082,ENSG00000150756,ENSG00000137312,ENSG00000178685,ENSG00000132256,ENSG00000147889,ENSG00000140575,ENSG00000137193,ENSG00000155096,ENSG00000175104,ENSG00000169554,ENSG00000127084,ENSG00000111859 |
| GO:0032753 | positive regulation of interleukin-4 production | 0.0008150 | 23 | 712 | 7 | 0.0098315 | 0.3043478 | GO:BP | ENSG00000135077,ENSG00000137265,ENSG00000158869,ENSG00000168961,ENSG00000122122,ENSG00000204592,ENSG00000198851 |
| GO:0051223 | regulation of protein transport | 0.0008388 | 755 | 712 | 54 | 0.0758427 | 0.0715232 | GO:BP | ENSG00000004468,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000135077,ENSG00000155657,ENSG00000182054,ENSG00000164111,ENSG00000196924,ENSG00000136167,ENSG00000167461,ENSG00000110090,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000204397,ENSG00000111640,ENSG00000103769,ENSG00000116288,ENSG00000134321,ENSG00000175793,ENSG00000187446,ENSG00000170312,ENSG00000122223,ENSG00000185651,ENSG00000117394,ENSG00000165949,ENSG00000204472,ENSG00000089685,ENSG00000118263,ENSG00000104805,ENSG00000180667,ENSG00000166197,ENSG00000021355,ENSG00000105220,ENSG00000133026,ENSG00000115267,ENSG00000168961,ENSG00000148175,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000111863,ENSG00000104765,ENSG00000070831,ENSG00000096968,ENSG00000170837,ENSG00000165527,ENSG00000102931,ENSG00000254087,ENSG00000160255,ENSG00000028137,ENSG00000175104,ENSG00000110218 |
| GO:0007010 | cytoskeleton organization | 0.0009820 | 1371 | 712 | 85 | 0.1193820 | 0.0619985 | GO:BP | ENSG00000196169,ENSG00000113721,ENSG00000183688,ENSG00000248905,ENSG00000072110,ENSG00000129595,ENSG00000157423,ENSG00000179218,ENSG00000147459,ENSG00000155657,ENSG00000160014,ENSG00000034510,ENSG00000101057,ENSG00000166503,ENSG00000125868,ENSG00000125864,ENSG00000117632,ENSG00000196924,ENSG00000112029,ENSG00000150093,ENSG00000136167,ENSG00000138160,ENSG00000125249,ENSG00000172757,ENSG00000232810,ENSG00000176293,ENSG00000111640,ENSG00000103769,ENSG00000108518,ENSG00000196230,ENSG00000131018,ENSG00000187446,ENSG00000130402,ENSG00000011426,ENSG00000071205,ENSG00000170312,ENSG00000105887,ENSG00000155846,ENSG00000123416,ENSG00000152229,ENSG00000213445,ENSG00000204472,ENSG00000089685,ENSG00000064666,ENSG00000173786,ENSG00000111229,ENSG00000163545,ENSG00000147065,ENSG00000166974,ENSG00000204899,ENSG00000128578,ENSG00000126016,ENSG00000206127,ENSG00000138071,ENSG00000166598,ENSG00000129007,ENSG00000131236,ENSG00000111348,ENSG00000143228,ENSG00000136717,ENSG00000131504,ENSG00000067560,ENSG00000132932,ENSG00000114166,ENSG00000075340,ENSG00000133026,ENSG00000158321,ENSG00000070831,ENSG00000152253,ENSG00000079691,ENSG00000151239,ENSG00000066279,ENSG00000075624,ENSG00000096968,ENSG00000165527,ENSG00000117155,ENSG00000116670,ENSG00000123338,ENSG00000171943,ENSG00000198736,ENSG00000153044,ENSG00000182628,ENSG00000139926,ENSG00000127084,ENSG00000111859 |
| GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 0.0010634 | 97 | 712 | 14 | 0.0196629 | 0.1443299 | GO:BP | ENSG00000164308,ENSG00000204267,ENSG00000092010,ENSG00000179218,ENSG00000231925,ENSG00000100911,ENSG00000167004,ENSG00000204264,ENSG00000166710,ENSG00000158869,ENSG00000204642,ENSG00000204592,ENSG00000127022,ENSG00000041357 |
| GO:0002456 | T cell mediated immunity | 0.0010634 | 97 | 712 | 14 | 0.0196629 | 0.1443299 | GO:BP | ENSG00000073861,ENSG00000186470,ENSG00000096996,ENSG00000153563,ENSG00000180644,ENSG00000073008,ENSG00000134321,ENSG00000166710,ENSG00000204642,ENSG00000122122,ENSG00000204592,ENSG00000153310,ENSG00000028137,ENSG00000175104 |
| GO:0032101 | regulation of response to external stimulus | 0.0010634 | 1132 | 712 | 73 | 0.1025281 | 0.0644876 | GO:BP | ENSG00000138496,ENSG00000113721,ENSG00000117281,ENSG00000092010,ENSG00000125347,ENSG00000179218,ENSG00000135077,ENSG00000154451,ENSG00000163840,ENSG00000089692,ENSG00000019582,ENSG00000130164,ENSG00000115415,ENSG00000155629,ENSG00000100911,ENSG00000221866,ENSG00000164111,ENSG00000170315,ENSG00000137265,ENSG00000123609,ENSG00000096996,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000204397,ENSG00000134352,ENSG00000116288,ENSG00000073008,ENSG00000134321,ENSG00000169855,ENSG00000152465,ENSG00000204264,ENSG00000077984,ENSG00000239713,ENSG00000213281,ENSG00000148400,ENSG00000204472,ENSG00000116030,ENSG00000185745,ENSG00000163823,ENSG00000129422,ENSG00000166598,ENSG00000156234,ENSG00000196954,ENSG00000158869,ENSG00000013725,ENSG00000163131,ENSG00000197417,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000204592,ENSG00000162676,ENSG00000111863,ENSG00000172936,ENSG00000096968,ENSG00000164164,ENSG00000128394,ENSG00000127666,ENSG00000132386,ENSG00000123338,ENSG00000142867,ENSG00000138646,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000127951,ENSG00000137312,ENSG00000196839,ENSG00000028137,ENSG00000132256,ENSG00000175104 |
| GO:0032268 | regulation of cellular protein metabolic process | 0.0010645 | 2744 | 712 | 149 | 0.2092697 | 0.0543003 | GO:BP | ENSG00000100453,ENSG00000138496,ENSG00000113721,ENSG00000229474,ENSG00000092010,ENSG00000179218,ENSG00000126709,ENSG00000184357,ENSG00000135077,ENSG00000155657,ENSG00000163840,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000160014,ENSG00000130164,ENSG00000100911,ENSG00000170315,ENSG00000169252,ENSG00000146674,ENSG00000118193,ENSG00000112029,ENSG00000117984,ENSG00000123609,ENSG00000165617,ENSG00000125249,ENSG00000111206,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000183691,ENSG00000117228,ENSG00000176890,ENSG00000204397,ENSG00000111640,ENSG00000134352,ENSG00000116288,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000103966,ENSG00000156463,ENSG00000143543,ENSG00000143742,ENSG00000188191,ENSG00000077984,ENSG00000187446,ENSG00000170312,ENSG00000105887,ENSG00000163359,ENSG00000185651,ENSG00000164830,ENSG00000070018,ENSG00000092853,ENSG00000055332,ENSG00000242372,ENSG00000169230,ENSG00000153094,ENSG00000159200,ENSG00000119335,ENSG00000148400,ENSG00000204472,ENSG00000089685,ENSG00000044574,ENSG00000188612,ENSG00000130741,ENSG00000116030,ENSG00000073803,ENSG00000163823,ENSG00000147065,ENSG00000180667,ENSG00000166197,ENSG00000154001,ENSG00000253626,ENSG00000073910,ENSG00000166598,ENSG00000148730,ENSG00000118971,ENSG00000021355,ENSG00000196954,ENSG00000185650,ENSG00000074800,ENSG00000105220,ENSG00000181467,ENSG00000136717,ENSG00000071994,ENSG00000170881,ENSG00000180574,ENSG00000075151,ENSG00000011485,ENSG00000067560,ENSG00000125944,ENSG00000127952,ENSG00000114166,ENSG00000189283,ENSG00000087302,ENSG00000168961,ENSG00000171617,ENSG00000141736,ENSG00000158321,ENSG00000118564,ENSG00000213626,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000162676,ENSG00000111863,ENSG00000106462,ENSG00000070831,ENSG00000172936,ENSG00000151239,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000079999,ENSG00000162385,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000138617,ENSG00000102931,ENSG00000116670,ENSG00000055163,ENSG00000132386,ENSG00000123338,ENSG00000140450,ENSG00000128272,ENSG00000142867,ENSG00000126432,ENSG00000138646,ENSG00000119318,ENSG00000172531,ENSG00000254087,ENSG00000160255,ENSG00000091127,ENSG00000177076,ENSG00000137312,ENSG00000198851,ENSG00000148218,ENSG00000135960,ENSG00000028137,ENSG00000178685,ENSG00000132256,ENSG00000147889,ENSG00000140575,ENSG00000175104,ENSG00000169554,ENSG00000111859 |
| GO:0051246 | regulation of protein metabolic process | 0.0010648 | 2922 | 712 | 157 | 0.2205056 | 0.0537303 | GO:BP | ENSG00000100453,ENSG00000138496,ENSG00000113721,ENSG00000229474,ENSG00000092010,ENSG00000125347,ENSG00000179218,ENSG00000126709,ENSG00000184357,ENSG00000135077,ENSG00000155657,ENSG00000163840,ENSG00000089692,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000160014,ENSG00000130164,ENSG00000100911,ENSG00000170315,ENSG00000105639,ENSG00000169252,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000118193,ENSG00000112029,ENSG00000117984,ENSG00000123609,ENSG00000165617,ENSG00000125249,ENSG00000111206,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000183691,ENSG00000117228,ENSG00000176890,ENSG00000204397,ENSG00000111640,ENSG00000134352,ENSG00000116288,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000103966,ENSG00000156463,ENSG00000143543,ENSG00000204264,ENSG00000143742,ENSG00000188191,ENSG00000077984,ENSG00000187446,ENSG00000170312,ENSG00000105887,ENSG00000163359,ENSG00000185651,ENSG00000164830,ENSG00000070018,ENSG00000092853,ENSG00000055332,ENSG00000242372,ENSG00000169230,ENSG00000153094,ENSG00000159200,ENSG00000119335,ENSG00000148400,ENSG00000204472,ENSG00000089685,ENSG00000044574,ENSG00000188612,ENSG00000130741,ENSG00000116030,ENSG00000073803,ENSG00000163823,ENSG00000147065,ENSG00000180667,ENSG00000166197,ENSG00000154001,ENSG00000253626,ENSG00000073910,ENSG00000166598,ENSG00000148730,ENSG00000118971,ENSG00000021355,ENSG00000196954,ENSG00000185650,ENSG00000074800,ENSG00000143476,ENSG00000105220,ENSG00000181467,ENSG00000136717,ENSG00000071994,ENSG00000170881,ENSG00000180574,ENSG00000075151,ENSG00000011485,ENSG00000067560,ENSG00000125944,ENSG00000127952,ENSG00000114166,ENSG00000189283,ENSG00000087302,ENSG00000168961,ENSG00000171617,ENSG00000141736,ENSG00000158321,ENSG00000118564,ENSG00000213626,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000162676,ENSG00000111863,ENSG00000106462,ENSG00000070831,ENSG00000172936,ENSG00000151239,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000079999,ENSG00000162385,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000138617,ENSG00000102931,ENSG00000116670,ENSG00000055163,ENSG00000132386,ENSG00000123338,ENSG00000140450,ENSG00000128272,ENSG00000142867,ENSG00000126432,ENSG00000138646,ENSG00000119318,ENSG00000172531,ENSG00000254087,ENSG00000160255,ENSG00000091127,ENSG00000177076,ENSG00000137312,ENSG00000198851,ENSG00000148218,ENSG00000135960,ENSG00000028137,ENSG00000178685,ENSG00000132256,ENSG00000147889,ENSG00000140575,ENSG00000155096,ENSG00000175104,ENSG00000169554,ENSG00000111859 |
| GO:0019883 | antigen processing and presentation of endogenous antigen | 0.0010668 | 24 | 712 | 7 | 0.0098315 | 0.2916667 | GO:BP | ENSG00000164308,ENSG00000204267,ENSG00000231925,ENSG00000019582,ENSG00000166710,ENSG00000204642,ENSG00000204592 |
| GO:0007154 | cell communication | 0.0011649 | 6798 | 712 | 322 | 0.4522472 | 0.0473669 | GO:BP | ENSG00000137441,ENSG00000100453,ENSG00000004468,ENSG00000119922,ENSG00000100450,ENSG00000138496,ENSG00000113721,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000198826,ENSG00000092010,ENSG00000156886,ENSG00000163599,ENSG00000132530,ENSG00000125347,ENSG00000108679,ENSG00000100321,ENSG00000180739,ENSG00000179218,ENSG00000002834,ENSG00000126709,ENSG00000135077,ENSG00000160932,ENSG00000165891,ENSG00000147459,ENSG00000155657,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000072135,ENSG00000203747,ENSG00000159216,ENSG00000160014,ENSG00000173482,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000155629,ENSG00000186469,ENSG00000069702,ENSG00000091129,ENSG00000100911,ENSG00000221866,ENSG00000205336,ENSG00000164111,ENSG00000113368,ENSG00000177156,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000166503,ENSG00000105639,ENSG00000117632,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000118193,ENSG00000120057,ENSG00000127947,ENSG00000186470,ENSG00000150093,ENSG00000136167,ENSG00000211746,ENSG00000167461,ENSG00000105409,ENSG00000123609,ENSG00000173848,ENSG00000096996,ENSG00000165617,ENSG00000125249,ENSG00000111206,ENSG00000172757,ENSG00000138795,ENSG00000211745,ENSG00000110090,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000189430,ENSG00000232810,ENSG00000183691,ENSG00000134539,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000126787,ENSG00000211721,ENSG00000204397,ENSG00000100749,ENSG00000108179,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000153563,ENSG00000103769,ENSG00000108518,ENSG00000128284,ENSG00000131171,ENSG00000189319,ENSG00000005844,ENSG00000130592,ENSG00000103148,ENSG00000211747,ENSG00000185201,ENSG00000116288,ENSG00000171596,ENSG00000213390,ENSG00000135114,ENSG00000134321,ENSG00000175793,ENSG00000169855,ENSG00000023572,ENSG00000152465,ENSG00000156463,ENSG00000204264,ENSG00000188191,ENSG00000114978,ENSG00000237254,ENSG00000187446,ENSG00000130402,ENSG00000071205,ENSG00000170312,ENSG00000155846,ENSG00000122223,ENSG00000185885,ENSG00000117394,ENSG00000172116,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000165949,ENSG00000061337,ENSG00000055332,ENSG00000169230,ENSG00000153094,ENSG00000065135,ENSG00000213445,ENSG00000213281,ENSG00000123131,ENSG00000159200,ENSG00000148400,ENSG00000157601,ENSG00000041353,ENSG00000089127,ENSG00000152256,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000121297,ENSG00000044574,ENSG00000171246,ENSG00000116030,ENSG00000007968,ENSG00000118263,ENSG00000064666,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000073803,ENSG00000159618,ENSG00000104805,ENSG00000163545,ENSG00000152778,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000166974,ENSG00000180667,ENSG00000154001,ENSG00000126016,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000129007,ENSG00000131236,ENSG00000110448,ENSG00000111348,ENSG00000148730,ENSG00000156234,ENSG00000129675,ENSG00000196954,ENSG00000183475,ENSG00000115155,ENSG00000185650,ENSG00000100605,ENSG00000111331,ENSG00000074800,ENSG00000143476,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000116983,ENSG00000168421,ENSG00000013725,ENSG00000134909,ENSG00000163131,ENSG00000100385,ENSG00000125148,ENSG00000184916,ENSG00000198821,ENSG00000011485,ENSG00000067560,ENSG00000213928,ENSG00000127952,ENSG00000114166,ENSG00000189283,ENSG00000213719,ENSG00000165304,ENSG00000172794,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000006625,ENSG00000168961,ENSG00000115339,ENSG00000115902,ENSG00000172270,ENSG00000122877,ENSG00000165283,ENSG00000141736,ENSG00000204592,ENSG00000103994,ENSG00000158321,ENSG00000174371,ENSG00000213626,ENSG00000167286,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000103495,ENSG00000162676,ENSG00000111863,ENSG00000106462,ENSG00000042753,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000101079,ENSG00000179583,ENSG00000171302,ENSG00000178719,ENSG00000141030,ENSG00000197043,ENSG00000132670,ENSG00000066279,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000176641,ENSG00000170837,ENSG00000165527,ENSG00000117155,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000105697,ENSG00000127022,ENSG00000197956,ENSG00000148908,ENSG00000196072,ENSG00000138617,ENSG00000102931,ENSG00000116670,ENSG00000055163,ENSG00000090520,ENSG00000256436,ENSG00000123338,ENSG00000128272,ENSG00000142867,ENSG00000111335,ENSG00000114126,ENSG00000143740,ENSG00000049541,ENSG00000172531,ENSG00000041357,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000143248,ENSG00000213366,ENSG00000111796,ENSG00000177076,ENSG00000101082,ENSG00000197409,ENSG00000131873,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000143321,ENSG00000155090,ENSG00000147168,ENSG00000177674,ENSG00000135960,ENSG00000028137,ENSG00000160753,ENSG00000132256,ENSG00000147889,ENSG00000140575,ENSG00000137193,ENSG00000160404,ENSG00000111450,ENSG00000175104,ENSG00000110218,ENSG00000169554,ENSG00000127084,ENSG00000113387,ENSG00000111859,ENSG00000112759,ENSG00000081985 |
| GO:0140014 | mitotic nuclear division | 0.0011671 | 271 | 712 | 26 | 0.0365169 | 0.0959410 | GO:BP | ENSG00000148773,ENSG00000113721,ENSG00000117724,ENSG00000155657,ENSG00000101057,ENSG00000156970,ENSG00000196924,ENSG00000118193,ENSG00000112029,ENSG00000138160,ENSG00000126787,ENSG00000103769,ENSG00000011426,ENSG00000089685,ENSG00000204899,ENSG00000122952,ENSG00000143228,ENSG00000067560,ENSG00000113810,ENSG00000070831,ENSG00000136824,ENSG00000109805,ENSG00000121579,ENSG00000116670,ENSG00000124688,ENSG00000134690 |
| GO:0002483 | antigen processing and presentation of endogenous peptide antigen | 0.0011834 | 17 | 712 | 6 | 0.0084270 | 0.3529412 | GO:BP | ENSG00000164308,ENSG00000204267,ENSG00000231925,ENSG00000166710,ENSG00000204642,ENSG00000204592 |
| GO:0002285 | lymphocyte activation involved in immune response | 0.0011883 | 180 | 712 | 20 | 0.0280899 | 0.1111111 | GO:BP | ENSG00000176083,ENSG00000073861,ENSG00000135077,ENSG00000105639,ENSG00000137265,ENSG00000136167,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000005844,ENSG00000122223,ENSG00000158869,ENSG00000204642,ENSG00000168961,ENSG00000174371,ENSG00000223496,ENSG00000116670,ENSG00000127951,ENSG00000196839,ENSG00000242574 |
| GO:0043065 | positive regulation of apoptotic process | 0.0011883 | 691 | 712 | 50 | 0.0702247 | 0.0723589 | GO:BP | ENSG00000100453,ENSG00000119922,ENSG00000113721,ENSG00000117281,ENSG00000163599,ENSG00000117560,ENSG00000164111,ENSG00000101057,ENSG00000170315,ENSG00000167004,ENSG00000146674,ENSG00000117984,ENSG00000150093,ENSG00000173848,ENSG00000111537,ENSG00000232810,ENSG00000134308,ENSG00000108179,ENSG00000111640,ENSG00000116288,ENSG00000175793,ENSG00000169855,ENSG00000169230,ENSG00000153094,ENSG00000148400,ENSG00000129675,ENSG00000196954,ENSG00000145649,ENSG00000136717,ENSG00000071994,ENSG00000067560,ENSG00000127952,ENSG00000165304,ENSG00000168961,ENSG00000131747,ENSG00000132792,ENSG00000104765,ENSG00000070831,ENSG00000096968,ENSG00000128272,ENSG00000142867,ENSG00000114126,ENSG00000172531,ENSG00000254087,ENSG00000177076,ENSG00000172667,ENSG00000028137,ENSG00000147889,ENSG00000175104,ENSG00000127084 |
| GO:0031349 | positive regulation of defense response | 0.0012056 | 509 | 712 | 40 | 0.0561798 | 0.0785855 | GO:BP | ENSG00000138496,ENSG00000117281,ENSG00000092010,ENSG00000125347,ENSG00000135077,ENSG00000154451,ENSG00000089692,ENSG00000130164,ENSG00000155629,ENSG00000100911,ENSG00000170315,ENSG00000137265,ENSG00000232810,ENSG00000134352,ENSG00000116288,ENSG00000073008,ENSG00000134321,ENSG00000204264,ENSG00000213281,ENSG00000166598,ENSG00000158869,ENSG00000013725,ENSG00000163131,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000204592,ENSG00000162676,ENSG00000172936,ENSG00000096968,ENSG00000164164,ENSG00000127666,ENSG00000142867,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000137312,ENSG00000132256,ENSG00000175104,ENSG00000170485 |
| GO:0065007 | biological regulation | 0.0012384 | 12628 | 712 | 549 | 0.7710674 | 0.0434748 | GO:BP | ENSG00000172057,ENSG00000100453,ENSG00000004468,ENSG00000148773,ENSG00000164308,ENSG00000179344,ENSG00000152217,ENSG00000156587,ENSG00000119922,ENSG00000100450,ENSG00000138496,ENSG00000113721,ENSG00000176083,ENSG00000117281,ENSG00000196126,ENSG00000183688,ENSG00000007402,ENSG00000198826,ENSG00000229474,ENSG00000092010,ENSG00000248905,ENSG00000072110,ENSG00000073861,ENSG00000156886,ENSG00000163599,ENSG00000132530,ENSG00000117724,ENSG00000125347,ENSG00000108679,ENSG00000100321,ENSG00000180739,ENSG00000179218,ENSG00000002834,ENSG00000126709,ENSG00000159674,ENSG00000175274,ENSG00000184357,ENSG00000135077,ENSG00000090857,ENSG00000092068,ENSG00000160932,ENSG00000165891,ENSG00000147459,ENSG00000154451,ENSG00000100427,ENSG00000155657,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000182054,ENSG00000163421,ENSG00000123485,ENSG00000231925,ENSG00000019582,ENSG00000142669,ENSG00000117560,ENSG00000144354,ENSG00000072135,ENSG00000164649,ENSG00000203747,ENSG00000159216,ENSG00000151502,ENSG00000160014,ENSG00000034510,ENSG00000173482,ENSG00000130164,ENSG00000127124,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000155629,ENSG00000186469,ENSG00000069702,ENSG00000091129,ENSG00000100911,ENSG00000197928,ENSG00000130511,ENSG00000221866,ENSG00000205336,ENSG00000164111,ENSG00000124191,ENSG00000198046,ENSG00000113368,ENSG00000101057,ENSG00000177156,ENSG00000163029,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000166503,ENSG00000156970,ENSG00000171848,ENSG00000125868,ENSG00000105639,ENSG00000117632,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000175550,ENSG00000169442,ENSG00000118193,ENSG00000112029,ENSG00000120057,ENSG00000117984,ENSG00000127947,ENSG00000186470,ENSG00000157216,ENSG00000150093,ENSG00000136167,ENSG00000211746,ENSG00000121039,ENSG00000167461,ENSG00000105409,ENSG00000123609,ENSG00000165512,ENSG00000173848,ENSG00000138160,ENSG00000096996,ENSG00000077312,ENSG00000165617,ENSG00000172331,ENSG00000125249,ENSG00000173114,ENSG00000111206,ENSG00000133321,ENSG00000172757,ENSG00000138795,ENSG00000211745,ENSG00000110090,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000112139,ENSG00000189430,ENSG00000099194,ENSG00000232810,ENSG00000183691,ENSG00000134539,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000126787,ENSG00000176890,ENSG00000211721,ENSG00000204397,ENSG00000176293,ENSG00000100749,ENSG00000108179,ENSG00000111640,ENSG00000118777,ENSG00000183734,ENSG00000172292,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000153563,ENSG00000103769,ENSG00000100380,ENSG00000108518,ENSG00000183741,ENSG00000128284,ENSG00000131171,ENSG00000189319,ENSG00000005844,ENSG00000130592,ENSG00000103148,ENSG00000211747,ENSG00000084092,ENSG00000185201,ENSG00000116288,ENSG00000196230,ENSG00000171596,ENSG00000180644,ENSG00000111602,ENSG00000103202,ENSG00000073008,ENSG00000213390,ENSG00000135114,ENSG00000134321,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000103966,ENSG00000124575,ENSG00000189420,ENSG00000023572,ENSG00000152465,ENSG00000156463,ENSG00000143543,ENSG00000204264,ENSG00000143742,ENSG00000051341,ENSG00000131018,ENSG00000196976,ENSG00000188191,ENSG00000077984,ENSG00000114978,ENSG00000237254,ENSG00000187446,ENSG00000130402,ENSG00000011426,ENSG00000071205,ENSG00000170312,ENSG00000105887,ENSG00000167618,ENSG00000155846,ENSG00000122223,ENSG00000136436,ENSG00000185885,ENSG00000163359,ENSG00000185651,ENSG00000164830,ENSG00000141576,ENSG00000117394,ENSG00000172116,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000125462,ENSG00000165949,ENSG00000185304,ENSG00000092853,ENSG00000061337,ENSG00000215305,ENSG00000055332,ENSG00000239713,ENSG00000242372,ENSG00000169230,ENSG00000153094,ENSG00000065135,ENSG00000213445,ENSG00000104687,ENSG00000213281,ENSG00000163520,ENSG00000123131,ENSG00000159200,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000164211,ENSG00000041353,ENSG00000089127,ENSG00000167723,ENSG00000152256,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000121297,ENSG00000163041,ENSG00000044574,ENSG00000124587,ENSG00000188612,ENSG00000171246,ENSG00000130741,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000073803,ENSG00000159618,ENSG00000104805,ENSG00000179632,ENSG00000163545,ENSG00000152778,ENSG00000185745,ENSG00000163823,ENSG00000233757,ENSG00000147065,ENSG00000166974,ENSG00000142556,ENSG00000166454,ENSG00000128578,ENSG00000180667,ENSG00000129422,ENSG00000166197,ENSG00000154001,ENSG00000126016,ENSG00000241258,ENSG00000253626,ENSG00000073910,ENSG00000131931,ENSG00000171970,ENSG00000138071,ENSG00000166598,ENSG00000129007,ENSG00000131236,ENSG00000157985,ENSG00000110448,ENSG00000107317,ENSG00000111348,ENSG00000148730,ENSG00000156234,ENSG00000108798,ENSG00000129675,ENSG00000118971,ENSG00000129534,ENSG00000021355,ENSG00000196954,ENSG00000183475,ENSG00000115155,ENSG00000093009,ENSG00000185650,ENSG00000100605,ENSG00000111331,ENSG00000074800,ENSG00000143476,ENSG00000172803,ENSG00000122952,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000171222,ENSG00000196449,ENSG00000053254,ENSG00000145649,ENSG00000136717,ENSG00000116983,ENSG00000071994,ENSG00000168421,ENSG00000013725,ENSG00000134909,ENSG00000158006,ENSG00000163131,ENSG00000170881,ENSG00000100385,ENSG00000130005,ENSG00000125148,ENSG00000139921,ENSG00000131504,ENSG00000184916,ENSG00000128039,ENSG00000180574,ENSG00000075151,ENSG00000198821,ENSG00000011485,ENSG00000067560,ENSG00000132932,ENSG00000197417,ENSG00000213928,ENSG00000125944,ENSG00000127952,ENSG00000183172,ENSG00000114166,ENSG00000189283,ENSG00000213719,ENSG00000165304,ENSG00000172794,ENSG00000075340,ENSG00000133026,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000144597,ENSG00000204642,ENSG00000115267,ENSG00000204256,ENSG00000087302,ENSG00000006625,ENSG00000168961,ENSG00000115339,ENSG00000122122,ENSG00000172270,ENSG00000122877,ENSG00000165283,ENSG00000173517,ENSG00000172795,ENSG00000148175,ENSG00000131747,ENSG00000171617,ENSG00000141736,ENSG00000162702,ENSG00000204592,ENSG00000132182,ENSG00000132792,ENSG00000103994,ENSG00000158321,ENSG00000174371,ENSG00000118564,ENSG00000160877,ENSG00000213626,ENSG00000167286,ENSG00000187608,ENSG00000157873,ENSG00000189369,ENSG00000198843,ENSG00000139579,ENSG00000103495,ENSG00000162676,ENSG00000111863,ENSG00000068489,ENSG00000106462,ENSG00000042753,ENSG00000153310,ENSG00000178996,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000079691,ENSG00000172936,ENSG00000124920,ENSG00000170860,ENSG00000171169,ENSG00000151239,ENSG00000101079,ENSG00000164088,ENSG00000243660,ENSG00000179583,ENSG00000171302,ENSG00000178719,ENSG00000166035,ENSG00000141030,ENSG00000197043,ENSG00000054965,ENSG00000189266,ENSG00000132670,ENSG00000066279,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000176542,ENSG00000128394,ENSG00000258289,ENSG00000176641,ENSG00000130348,ENSG00000079999,ENSG00000113068,ENSG00000170837,ENSG00000165527,ENSG00000117155,ENSG00000105612,ENSG00000162385,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000109084,ENSG00000105697,ENSG00000223496,ENSG00000127022,ENSG00000197956,ENSG00000026751,ENSG00000148908,ENSG00000196072,ENSG00000138617,ENSG00000184897,ENSG00000102931,ENSG00000125648,ENSG00000116670,ENSG00000184154,ENSG00000072571,ENSG00000055163,ENSG00000184640,ENSG00000090520,ENSG00000132386,ENSG00000049239,ENSG00000256436,ENSG00000123338,ENSG00000010270,ENSG00000140450,ENSG00000171943,ENSG00000128272,ENSG00000134049,ENSG00000148337,ENSG00000124688,ENSG00000142867,ENSG00000110852,ENSG00000111335,ENSG00000114126,ENSG00000143740,ENSG00000126432,ENSG00000145337,ENSG00000138646,ENSG00000049541,ENSG00000196834,ENSG00000119318,ENSG00000172531,ENSG00000178691,ENSG00000129968,ENSG00000137309,ENSG00000041357,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000152601,ENSG00000143248,ENSG00000091127,ENSG00000213366,ENSG00000182628,ENSG00000111796,ENSG00000177076,ENSG00000127951,ENSG00000137310,ENSG00000155660,ENSG00000101082,ENSG00000164576,ENSG00000131019,ENSG00000197409,ENSG00000172667,ENSG00000150756,ENSG00000131873,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000143321,ENSG00000136104,ENSG00000089693,ENSG00000155090,ENSG00000148218,ENSG00000242574,ENSG00000147168,ENSG00000177674,ENSG00000135960,ENSG00000011007,ENSG00000028137,ENSG00000160753,ENSG00000178685,ENSG00000169223,ENSG00000132256,ENSG00000147889,ENSG00000139926,ENSG00000140575,ENSG00000137193,ENSG00000160404,ENSG00000111450,ENSG00000155096,ENSG00000175104,ENSG00000078124,ENSG00000110218,ENSG00000169554,ENSG00000127084,ENSG00000120280,ENSG00000113387,ENSG00000166794,ENSG00000111859,ENSG00000147180,ENSG00000170485,ENSG00000130818,ENSG00000112759,ENSG00000081985 |
| GO:0022607 | cellular component assembly | 0.0012428 | 3000 | 712 | 160 | 0.2247191 | 0.0533333 | GO:BP | ENSG00000113721,ENSG00000196126,ENSG00000229474,ENSG00000248905,ENSG00000072110,ENSG00000117724,ENSG00000157423,ENSG00000179218,ENSG00000184357,ENSG00000154451,ENSG00000100427,ENSG00000155657,ENSG00000123485,ENSG00000231925,ENSG00000019582,ENSG00000198513,ENSG00000159216,ENSG00000034510,ENSG00000069702,ENSG00000091129,ENSG00000101057,ENSG00000170315,ENSG00000166503,ENSG00000171848,ENSG00000117632,ENSG00000169252,ENSG00000160654,ENSG00000196924,ENSG00000118193,ENSG00000112029,ENSG00000157216,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000138160,ENSG00000165617,ENSG00000125249,ENSG00000173114,ENSG00000138795,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000112139,ENSG00000232810,ENSG00000117228,ENSG00000103769,ENSG00000100380,ENSG00000108518,ENSG00000103148,ENSG00000137474,ENSG00000116288,ENSG00000196230,ENSG00000180644,ENSG00000103966,ENSG00000124575,ENSG00000100918,ENSG00000105011,ENSG00000051341,ENSG00000187446,ENSG00000130402,ENSG00000188312,ENSG00000011426,ENSG00000170312,ENSG00000105887,ENSG00000117394,ENSG00000139182,ENSG00000171603,ENSG00000215305,ENSG00000055332,ENSG00000242372,ENSG00000153094,ENSG00000119335,ENSG00000148400,ENSG00000204472,ENSG00000089685,ENSG00000163041,ENSG00000044574,ENSG00000130741,ENSG00000116030,ENSG00000132274,ENSG00000166710,ENSG00000111229,ENSG00000147065,ENSG00000166974,ENSG00000166454,ENSG00000204899,ENSG00000206127,ENSG00000138071,ENSG00000166598,ENSG00000156234,ENSG00000129675,ENSG00000129534,ENSG00000115155,ENSG00000093009,ENSG00000084623,ENSG00000158869,ENSG00000136717,ENSG00000100385,ENSG00000131504,ENSG00000180574,ENSG00000198821,ENSG00000067560,ENSG00000127952,ENSG00000114166,ENSG00000075340,ENSG00000133026,ENSG00000204256,ENSG00000151466,ENSG00000165283,ENSG00000173517,ENSG00000148175,ENSG00000132963,ENSG00000132182,ENSG00000158321,ENSG00000174371,ENSG00000160877,ENSG00000167286,ENSG00000042753,ENSG00000176101,ENSG00000070831,ENSG00000079691,ENSG00000170860,ENSG00000151239,ENSG00000197043,ENSG00000066279,ENSG00000075624,ENSG00000096968,ENSG00000165527,ENSG00000117155,ENSG00000127666,ENSG00000184897,ENSG00000055163,ENSG00000184640,ENSG00000127774,ENSG00000123338,ENSG00000171943,ENSG00000142867,ENSG00000109390,ENSG00000143740,ENSG00000198736,ENSG00000104738,ENSG00000119318,ENSG00000153044,ENSG00000137309,ENSG00000125354,ENSG00000189306,ENSG00000197409,ENSG00000137312,ENSG00000198851,ENSG00000232838,ENSG00000148218,ENSG00000242574,ENSG00000178685,ENSG00000147889,ENSG00000140575,ENSG00000111450,ENSG00000110218,ENSG00000127084,ENSG00000113387,ENSG00000111859 |
| GO:0007165 | signal transduction | 0.0012568 | 6296 | 712 | 301 | 0.4227528 | 0.0478081 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000119922,ENSG00000100450,ENSG00000138496,ENSG00000113721,ENSG00000117281,ENSG00000196126,ENSG00000198826,ENSG00000092010,ENSG00000156886,ENSG00000163599,ENSG00000132530,ENSG00000125347,ENSG00000108679,ENSG00000180739,ENSG00000179218,ENSG00000002834,ENSG00000126709,ENSG00000135077,ENSG00000160932,ENSG00000165891,ENSG00000147459,ENSG00000155657,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000072135,ENSG00000203747,ENSG00000159216,ENSG00000160014,ENSG00000173482,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000155629,ENSG00000186469,ENSG00000069702,ENSG00000100911,ENSG00000221866,ENSG00000205336,ENSG00000164111,ENSG00000113368,ENSG00000177156,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000166503,ENSG00000105639,ENSG00000117632,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000118193,ENSG00000120057,ENSG00000127947,ENSG00000186470,ENSG00000150093,ENSG00000136167,ENSG00000211746,ENSG00000167461,ENSG00000123609,ENSG00000173848,ENSG00000096996,ENSG00000165617,ENSG00000125249,ENSG00000111206,ENSG00000172757,ENSG00000138795,ENSG00000211745,ENSG00000111537,ENSG00000179051,ENSG00000189430,ENSG00000232810,ENSG00000183691,ENSG00000134539,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000126787,ENSG00000211721,ENSG00000204397,ENSG00000100749,ENSG00000108179,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000153563,ENSG00000103769,ENSG00000108518,ENSG00000128284,ENSG00000131171,ENSG00000189319,ENSG00000005844,ENSG00000130592,ENSG00000103148,ENSG00000211747,ENSG00000185201,ENSG00000116288,ENSG00000171596,ENSG00000213390,ENSG00000135114,ENSG00000134321,ENSG00000175793,ENSG00000169855,ENSG00000023572,ENSG00000152465,ENSG00000156463,ENSG00000204264,ENSG00000188191,ENSG00000114978,ENSG00000237254,ENSG00000187446,ENSG00000130402,ENSG00000071205,ENSG00000170312,ENSG00000155846,ENSG00000122223,ENSG00000185885,ENSG00000172116,ENSG00000070018,ENSG00000165949,ENSG00000055332,ENSG00000169230,ENSG00000153094,ENSG00000065135,ENSG00000213445,ENSG00000213281,ENSG00000123131,ENSG00000159200,ENSG00000148400,ENSG00000157601,ENSG00000041353,ENSG00000089127,ENSG00000152256,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000044574,ENSG00000171246,ENSG00000116030,ENSG00000007968,ENSG00000064666,ENSG00000132274,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000073803,ENSG00000159618,ENSG00000104805,ENSG00000163545,ENSG00000152778,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000166974,ENSG00000180667,ENSG00000154001,ENSG00000126016,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000129007,ENSG00000131236,ENSG00000110448,ENSG00000111348,ENSG00000148730,ENSG00000156234,ENSG00000129675,ENSG00000196954,ENSG00000183475,ENSG00000185650,ENSG00000100605,ENSG00000111331,ENSG00000074800,ENSG00000143476,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000116983,ENSG00000168421,ENSG00000013725,ENSG00000134909,ENSG00000163131,ENSG00000100385,ENSG00000125148,ENSG00000184916,ENSG00000198821,ENSG00000011485,ENSG00000067560,ENSG00000213928,ENSG00000127952,ENSG00000114166,ENSG00000189283,ENSG00000213719,ENSG00000165304,ENSG00000172794,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000006625,ENSG00000168961,ENSG00000115339,ENSG00000172270,ENSG00000165283,ENSG00000141736,ENSG00000204592,ENSG00000103994,ENSG00000158321,ENSG00000174371,ENSG00000213626,ENSG00000167286,ENSG00000187608,ENSG00000157873,ENSG00000103495,ENSG00000162676,ENSG00000111863,ENSG00000106462,ENSG00000042753,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000101079,ENSG00000179583,ENSG00000171302,ENSG00000178719,ENSG00000141030,ENSG00000197043,ENSG00000132670,ENSG00000066279,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000176641,ENSG00000170837,ENSG00000165527,ENSG00000117155,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000105697,ENSG00000127022,ENSG00000197956,ENSG00000148908,ENSG00000196072,ENSG00000138617,ENSG00000102931,ENSG00000116670,ENSG00000055163,ENSG00000090520,ENSG00000256436,ENSG00000123338,ENSG00000128272,ENSG00000142867,ENSG00000111335,ENSG00000114126,ENSG00000049541,ENSG00000172531,ENSG00000041357,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000143248,ENSG00000213366,ENSG00000111796,ENSG00000177076,ENSG00000101082,ENSG00000197409,ENSG00000131873,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000143321,ENSG00000147168,ENSG00000177674,ENSG00000135960,ENSG00000028137,ENSG00000160753,ENSG00000132256,ENSG00000147889,ENSG00000140575,ENSG00000137193,ENSG00000160404,ENSG00000111450,ENSG00000175104,ENSG00000169554,ENSG00000127084,ENSG00000113387,ENSG00000111859,ENSG00000112759,ENSG00000081985 |
| GO:0070757 | interleukin-35-mediated signaling pathway | 0.0012902 | 11 | 712 | 5 | 0.0070225 | 0.4545455 | GO:BP | ENSG00000115415,ENSG00000134352,ENSG00000096968,ENSG00000127022,ENSG00000081985 |
| GO:0002224 | toll-like receptor signaling pathway | 0.0013225 | 153 | 712 | 18 | 0.0252809 | 0.1176471 | GO:BP | ENSG00000125347,ENSG00000135077,ENSG00000155629,ENSG00000170315,ENSG00000137265,ENSG00000134321,ENSG00000166598,ENSG00000163131,ENSG00000185507,ENSG00000162676,ENSG00000172936,ENSG00000164164,ENSG00000127666,ENSG00000142867,ENSG00000254087,ENSG00000160255,ENSG00000137312,ENSG00000175104 |
| GO:0007264 | small GTPase mediated signal transduction | 0.0013242 | 584 | 712 | 44 | 0.0617978 | 0.0753425 | GO:BP | ENSG00000113721,ENSG00000198826,ENSG00000147459,ENSG00000205336,ENSG00000117632,ENSG00000118193,ENSG00000150093,ENSG00000167461,ENSG00000173848,ENSG00000125249,ENSG00000111206,ENSG00000172757,ENSG00000134308,ENSG00000103769,ENSG00000116288,ENSG00000213390,ENSG00000169855,ENSG00000187446,ENSG00000071205,ENSG00000213445,ENSG00000213281,ENSG00000148400,ENSG00000041353,ENSG00000204472,ENSG00000104805,ENSG00000166974,ENSG00000126016,ENSG00000111348,ENSG00000129675,ENSG00000181467,ENSG00000168421,ENSG00000134909,ENSG00000067560,ENSG00000172794,ENSG00000158321,ENSG00000070831,ENSG00000096968,ENSG00000165527,ENSG00000117155,ENSG00000254087,ENSG00000139998,ENSG00000137312,ENSG00000147889,ENSG00000127084 |
| GO:0032103 | positive regulation of response to external stimulus | 0.0013644 | 640 | 712 | 47 | 0.0660112 | 0.0734375 | GO:BP | ENSG00000138496,ENSG00000113721,ENSG00000117281,ENSG00000092010,ENSG00000125347,ENSG00000179218,ENSG00000135077,ENSG00000154451,ENSG00000089692,ENSG00000019582,ENSG00000130164,ENSG00000155629,ENSG00000100911,ENSG00000170315,ENSG00000137265,ENSG00000232810,ENSG00000134352,ENSG00000116288,ENSG00000073008,ENSG00000134321,ENSG00000204264,ENSG00000213281,ENSG00000204472,ENSG00000163823,ENSG00000166598,ENSG00000156234,ENSG00000158869,ENSG00000013725,ENSG00000163131,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000204592,ENSG00000162676,ENSG00000172936,ENSG00000096968,ENSG00000164164,ENSG00000127666,ENSG00000123338,ENSG00000142867,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000137312,ENSG00000132256,ENSG00000175104 |
| GO:0032609 | interferon-gamma production | 0.0014027 | 113 | 712 | 15 | 0.0210674 | 0.1327434 | GO:BP | ENSG00000117281,ENSG00000196126,ENSG00000135077,ENSG00000223865,ENSG00000231389,ENSG00000186470,ENSG00000096996,ENSG00000232810,ENSG00000122223,ENSG00000168961,ENSG00000122122,ENSG00000187608,ENSG00000153310,ENSG00000198851,ENSG00000081985 |
| GO:0048523 | negative regulation of cellular process | 0.0015086 | 4996 | 712 | 246 | 0.3455056 | 0.0492394 | GO:BP | ENSG00000172057,ENSG00000100453,ENSG00000004468,ENSG00000138496,ENSG00000113721,ENSG00000117281,ENSG00000196126,ENSG00000183688,ENSG00000229474,ENSG00000092010,ENSG00000072110,ENSG00000073861,ENSG00000163599,ENSG00000117724,ENSG00000125347,ENSG00000179218,ENSG00000126709,ENSG00000175274,ENSG00000184357,ENSG00000135077,ENSG00000165891,ENSG00000163840,ENSG00000089692,ENSG00000182054,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000072135,ENSG00000159216,ENSG00000160014,ENSG00000034510,ENSG00000173482,ENSG00000130164,ENSG00000115415,ENSG00000119917,ENSG00000069702,ENSG00000100911,ENSG00000221866,ENSG00000205336,ENSG00000164111,ENSG00000170315,ENSG00000166503,ENSG00000156970,ENSG00000171848,ENSG00000105639,ENSG00000117632,ENSG00000169252,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000175550,ENSG00000118193,ENSG00000112029,ENSG00000120057,ENSG00000127947,ENSG00000150093,ENSG00000123609,ENSG00000165617,ENSG00000125249,ENSG00000111206,ENSG00000133321,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000232810,ENSG00000183691,ENSG00000117228,ENSG00000134308,ENSG00000176890,ENSG00000204397,ENSG00000108179,ENSG00000111640,ENSG00000183734,ENSG00000134352,ENSG00000132646,ENSG00000100380,ENSG00000108518,ENSG00000183741,ENSG00000103148,ENSG00000116288,ENSG00000111602,ENSG00000134321,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000124575,ENSG00000156463,ENSG00000204264,ENSG00000143742,ENSG00000051341,ENSG00000188191,ENSG00000077984,ENSG00000187446,ENSG00000130402,ENSG00000071205,ENSG00000170312,ENSG00000105887,ENSG00000155846,ENSG00000185885,ENSG00000163359,ENSG00000164830,ENSG00000141576,ENSG00000070018,ENSG00000165949,ENSG00000092853,ENSG00000061337,ENSG00000055332,ENSG00000239713,ENSG00000242372,ENSG00000169230,ENSG00000065135,ENSG00000213445,ENSG00000123131,ENSG00000159200,ENSG00000119335,ENSG00000148400,ENSG00000204472,ENSG00000089685,ENSG00000121297,ENSG00000163041,ENSG00000044574,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000132274,ENSG00000166710,ENSG00000179632,ENSG00000163545,ENSG00000180667,ENSG00000073910,ENSG00000131931,ENSG00000166598,ENSG00000111348,ENSG00000148730,ENSG00000156234,ENSG00000118971,ENSG00000021355,ENSG00000093009,ENSG00000185650,ENSG00000074800,ENSG00000143476,ENSG00000122952,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000053254,ENSG00000145649,ENSG00000136717,ENSG00000168421,ENSG00000158006,ENSG00000170881,ENSG00000100385,ENSG00000131504,ENSG00000184916,ENSG00000011485,ENSG00000067560,ENSG00000132932,ENSG00000125944,ENSG00000127952,ENSG00000114166,ENSG00000189283,ENSG00000075340,ENSG00000185507,ENSG00000100298,ENSG00000204642,ENSG00000087302,ENSG00000168961,ENSG00000172795,ENSG00000131747,ENSG00000171617,ENSG00000141736,ENSG00000162702,ENSG00000160877,ENSG00000213626,ENSG00000187608,ENSG00000157873,ENSG00000139579,ENSG00000103495,ENSG00000162676,ENSG00000111863,ENSG00000068489,ENSG00000106462,ENSG00000104765,ENSG00000070831,ENSG00000079691,ENSG00000172936,ENSG00000171169,ENSG00000151239,ENSG00000101079,ENSG00000179583,ENSG00000178719,ENSG00000197043,ENSG00000066279,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000176542,ENSG00000128394,ENSG00000176641,ENSG00000165527,ENSG00000168329,ENSG00000127666,ENSG00000105697,ENSG00000148908,ENSG00000138617,ENSG00000184897,ENSG00000116670,ENSG00000132386,ENSG00000123338,ENSG00000171943,ENSG00000128272,ENSG00000124688,ENSG00000142867,ENSG00000114126,ENSG00000126432,ENSG00000178691,ENSG00000137309,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000143248,ENSG00000091127,ENSG00000213366,ENSG00000177076,ENSG00000127951,ENSG00000101082,ENSG00000197409,ENSG00000198851,ENSG00000196839,ENSG00000143321,ENSG00000136104,ENSG00000155090,ENSG00000148218,ENSG00000028137,ENSG00000178685,ENSG00000147889,ENSG00000140575,ENSG00000137193,ENSG00000175104,ENSG00000169554,ENSG00000113387,ENSG00000170485 |
| GO:0043068 | positive regulation of programmed cell death | 0.0015086 | 699 | 712 | 50 | 0.0702247 | 0.0715308 | GO:BP | ENSG00000100453,ENSG00000119922,ENSG00000113721,ENSG00000117281,ENSG00000163599,ENSG00000117560,ENSG00000164111,ENSG00000101057,ENSG00000170315,ENSG00000167004,ENSG00000146674,ENSG00000117984,ENSG00000150093,ENSG00000173848,ENSG00000111537,ENSG00000232810,ENSG00000134308,ENSG00000108179,ENSG00000111640,ENSG00000116288,ENSG00000175793,ENSG00000169855,ENSG00000169230,ENSG00000153094,ENSG00000148400,ENSG00000129675,ENSG00000196954,ENSG00000145649,ENSG00000136717,ENSG00000071994,ENSG00000067560,ENSG00000127952,ENSG00000165304,ENSG00000168961,ENSG00000131747,ENSG00000132792,ENSG00000104765,ENSG00000070831,ENSG00000096968,ENSG00000128272,ENSG00000142867,ENSG00000114126,ENSG00000172531,ENSG00000254087,ENSG00000177076,ENSG00000172667,ENSG00000028137,ENSG00000147889,ENSG00000175104,ENSG00000127084 |
| GO:0032649 | regulation of interferon-gamma production | 0.0015191 | 101 | 712 | 14 | 0.0196629 | 0.1386139 | GO:BP | ENSG00000117281,ENSG00000196126,ENSG00000135077,ENSG00000223865,ENSG00000231389,ENSG00000096996,ENSG00000232810,ENSG00000122223,ENSG00000168961,ENSG00000122122,ENSG00000187608,ENSG00000153310,ENSG00000198851,ENSG00000081985 |
| GO:0008284 | positive regulation of cell population proliferation | 0.0015191 | 969 | 712 | 64 | 0.0898876 | 0.0660475 | GO:BP | ENSG00000004468,ENSG00000113721,ENSG00000179218,ENSG00000135077,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000164649,ENSG00000115415,ENSG00000069702,ENSG00000205336,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000196924,ENSG00000118193,ENSG00000112029,ENSG00000157216,ENSG00000150093,ENSG00000096996,ENSG00000111206,ENSG00000138795,ENSG00000111537,ENSG00000102554,ENSG00000232810,ENSG00000183691,ENSG00000134352,ENSG00000170312,ENSG00000065135,ENSG00000213281,ENSG00000148400,ENSG00000204472,ENSG00000089685,ENSG00000166197,ENSG00000118971,ENSG00000071994,ENSG00000013725,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000204592,ENSG00000160877,ENSG00000213626,ENSG00000103495,ENSG00000106462,ENSG00000070831,ENSG00000172936,ENSG00000066279,ENSG00000096968,ENSG00000168329,ENSG00000127666,ENSG00000197956,ENSG00000123338,ENSG00000178691,ENSG00000254087,ENSG00000177076,ENSG00000198851,ENSG00000196839,ENSG00000136104,ENSG00000242574,ENSG00000137193,ENSG00000175104,ENSG00000078124,ENSG00000081985 |
| GO:0002833 | positive regulation of response to biotic stimulus | 0.0015264 | 393 | 712 | 33 | 0.0463483 | 0.0839695 | GO:BP | ENSG00000138496,ENSG00000117281,ENSG00000092010,ENSG00000125347,ENSG00000135077,ENSG00000154451,ENSG00000089692,ENSG00000155629,ENSG00000100911,ENSG00000170315,ENSG00000137265,ENSG00000073008,ENSG00000134321,ENSG00000204264,ENSG00000213281,ENSG00000166598,ENSG00000158869,ENSG00000163131,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000204592,ENSG00000162676,ENSG00000172936,ENSG00000164164,ENSG00000127666,ENSG00000142867,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000137312,ENSG00000132256,ENSG00000175104 |
| GO:2000116 | regulation of cysteine-type endopeptidase activity | 0.0015264 | 245 | 712 | 24 | 0.0337079 | 0.0979592 | GO:BP | ENSG00000126709,ENSG00000117560,ENSG00000117984,ENSG00000138795,ENSG00000232810,ENSG00000204397,ENSG00000116288,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000077984,ENSG00000153094,ENSG00000089685,ENSG00000196954,ENSG00000105220,ENSG00000071994,ENSG00000067560,ENSG00000168961,ENSG00000096968,ENSG00000055163,ENSG00000142867,ENSG00000126432,ENSG00000177076,ENSG00000147889 |
| GO:0050852 | T cell receptor signaling pathway | 0.0015264 | 199 | 712 | 21 | 0.0294944 | 0.1055276 | GO:BP | ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000163599,ENSG00000196735,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000160654,ENSG00000186470,ENSG00000117228,ENSG00000204264,ENSG00000211810,ENSG00000198821,ENSG00000165283,ENSG00000167286,ENSG00000142867,ENSG00000041357,ENSG00000198851,ENSG00000196839,ENSG00000175104 |
| GO:0002711 | positive regulation of T cell mediated immunity | 0.0015785 | 44 | 712 | 9 | 0.0126404 | 0.2045455 | GO:BP | ENSG00000096996,ENSG00000073008,ENSG00000134321,ENSG00000166710,ENSG00000204642,ENSG00000122122,ENSG00000204592,ENSG00000153310,ENSG00000175104 |
| GO:0002253 | activation of immune response | 0.0016371 | 721 | 712 | 51 | 0.0716292 | 0.0707351 | GO:BP | ENSG00000004468,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000196735,ENSG00000203747,ENSG00000159216,ENSG00000155629,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000160654,ENSG00000137265,ENSG00000186470,ENSG00000117228,ENSG00000134321,ENSG00000204264,ENSG00000213281,ENSG00000211810,ENSG00000111229,ENSG00000138071,ENSG00000166598,ENSG00000158869,ENSG00000163131,ENSG00000198821,ENSG00000185507,ENSG00000115267,ENSG00000165283,ENSG00000167286,ENSG00000162676,ENSG00000070831,ENSG00000172936,ENSG00000075624,ENSG00000164164,ENSG00000127666,ENSG00000055163,ENSG00000123338,ENSG00000142867,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000101082,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000132256,ENSG00000175104 |
| GO:0009306 | protein secretion | 0.0017989 | 630 | 712 | 46 | 0.0646067 | 0.0730159 | GO:BP | ENSG00000004468,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000135077,ENSG00000154451,ENSG00000155657,ENSG00000182054,ENSG00000164111,ENSG00000186470,ENSG00000167461,ENSG00000110090,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000204397,ENSG00000111640,ENSG00000116288,ENSG00000134321,ENSG00000122223,ENSG00000117394,ENSG00000148400,ENSG00000204472,ENSG00000089685,ENSG00000118263,ENSG00000021355,ENSG00000105220,ENSG00000133026,ENSG00000115267,ENSG00000168961,ENSG00000204592,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000111863,ENSG00000096968,ENSG00000170837,ENSG00000165527,ENSG00000127022,ENSG00000102931,ENSG00000254087,ENSG00000139998,ENSG00000155660,ENSG00000028137,ENSG00000175104,ENSG00000110218 |
| GO:0035592 | establishment of protein localization to extracellular region | 0.0018603 | 631 | 712 | 46 | 0.0646067 | 0.0729002 | GO:BP | ENSG00000004468,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000135077,ENSG00000154451,ENSG00000155657,ENSG00000182054,ENSG00000164111,ENSG00000186470,ENSG00000167461,ENSG00000110090,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000204397,ENSG00000111640,ENSG00000116288,ENSG00000134321,ENSG00000122223,ENSG00000117394,ENSG00000148400,ENSG00000204472,ENSG00000089685,ENSG00000118263,ENSG00000021355,ENSG00000105220,ENSG00000133026,ENSG00000115267,ENSG00000168961,ENSG00000204592,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000111863,ENSG00000096968,ENSG00000170837,ENSG00000165527,ENSG00000127022,ENSG00000102931,ENSG00000254087,ENSG00000139998,ENSG00000155660,ENSG00000028137,ENSG00000175104,ENSG00000110218 |
| GO:0002709 | regulation of T cell mediated immunity | 0.0019723 | 67 | 712 | 11 | 0.0154494 | 0.1641791 | GO:BP | ENSG00000073861,ENSG00000096996,ENSG00000073008,ENSG00000134321,ENSG00000166710,ENSG00000204642,ENSG00000122122,ENSG00000204592,ENSG00000153310,ENSG00000028137,ENSG00000175104 |
| GO:0001910 | regulation of leukocyte mediated cytotoxicity | 0.0019723 | 67 | 712 | 11 | 0.0154494 | 0.1641791 | GO:BP | ENSG00000117281,ENSG00000135077,ENSG00000089692,ENSG00000096996,ENSG00000189430,ENSG00000073008,ENSG00000166710,ENSG00000204642,ENSG00000168961,ENSG00000204592,ENSG00000153310 |
| GO:0002477 | antigen processing and presentation of exogenous peptide antigen via MHC class Ib | 0.0019890 | 3 | 712 | 3 | 0.0042135 | 1.0000000 | GO:BP | ENSG00000166710,ENSG00000204642,ENSG00000204592 |
| GO:0070458 | cellular detoxification of nitrogen compound | 0.0019890 | 3 | 712 | 3 | 0.0042135 | 1.0000000 | GO:BP | ENSG00000134184,ENSG00000134202,ENSG00000213366 |
| GO:0002519 | natural killer cell tolerance induction | 0.0019890 | 3 | 712 | 3 | 0.0042135 | 1.0000000 | GO:BP | ENSG00000135077,ENSG00000168961,ENSG00000204592 |
| GO:0045620 | negative regulation of lymphocyte differentiation | 0.0019917 | 56 | 712 | 10 | 0.0140449 | 0.1785714 | GO:BP | ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000105639,ENSG00000141736,ENSG00000127951,ENSG00000147889 |
| GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 0.0019924 | 79 | 712 | 12 | 0.0168539 | 0.1518987 | GO:BP | ENSG00000204267,ENSG00000092010,ENSG00000179218,ENSG00000231925,ENSG00000100911,ENSG00000167004,ENSG00000204264,ENSG00000166710,ENSG00000158869,ENSG00000204642,ENSG00000204592,ENSG00000041357 |
| GO:1901700 | response to oxygen-containing compound | 0.0022201 | 1746 | 712 | 101 | 0.1418539 | 0.0578465 | GO:BP | ENSG00000004468,ENSG00000113721,ENSG00000196126,ENSG00000179218,ENSG00000159674,ENSG00000135077,ENSG00000100427,ENSG00000117560,ENSG00000160014,ENSG00000130164,ENSG00000115415,ENSG00000186469,ENSG00000069702,ENSG00000164111,ENSG00000105639,ENSG00000169252,ENSG00000196924,ENSG00000167461,ENSG00000105409,ENSG00000173848,ENSG00000172757,ENSG00000110090,ENSG00000102554,ENSG00000099194,ENSG00000232810,ENSG00000176890,ENSG00000204397,ENSG00000108179,ENSG00000132646,ENSG00000116288,ENSG00000111602,ENSG00000023572,ENSG00000137563,ENSG00000188191,ENSG00000170312,ENSG00000155846,ENSG00000164830,ENSG00000117394,ENSG00000070018,ENSG00000242372,ENSG00000153094,ENSG00000065135,ENSG00000213445,ENSG00000148400,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000044574,ENSG00000118263,ENSG00000173786,ENSG00000147065,ENSG00000138071,ENSG00000166598,ENSG00000148730,ENSG00000156234,ENSG00000196954,ENSG00000185650,ENSG00000105220,ENSG00000100299,ENSG00000013725,ENSG00000011485,ENSG00000067560,ENSG00000197417,ENSG00000114166,ENSG00000168961,ENSG00000172270,ENSG00000122877,ENSG00000103994,ENSG00000198843,ENSG00000162676,ENSG00000106462,ENSG00000172936,ENSG00000132670,ENSG00000075624,ENSG00000096968,ENSG00000170837,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000105697,ENSG00000148908,ENSG00000132386,ENSG00000049239,ENSG00000128272,ENSG00000142867,ENSG00000126432,ENSG00000254087,ENSG00000177076,ENSG00000196839,ENSG00000155090,ENSG00000148218,ENSG00000177674,ENSG00000028137,ENSG00000132256,ENSG00000140575,ENSG00000137193,ENSG00000111450,ENSG00000175104,ENSG00000110218,ENSG00000112759,ENSG00000081985 |
| GO:0002440 | production of molecular mediator of immune response | 0.0022908 | 301 | 712 | 27 | 0.0379213 | 0.0897010 | GO:BP | ENSG00000179344,ENSG00000117281,ENSG00000196126,ENSG00000073861,ENSG00000159674,ENSG00000019582,ENSG00000105639,ENSG00000232810,ENSG00000134321,ENSG00000051341,ENSG00000122223,ENSG00000166710,ENSG00000105220,ENSG00000158869,ENSG00000204642,ENSG00000122122,ENSG00000204592,ENSG00000132792,ENSG00000174371,ENSG00000157873,ENSG00000127666,ENSG00000223496,ENSG00000116670,ENSG00000142867,ENSG00000127951,ENSG00000028137,ENSG00000175104 |
| GO:0002763 | positive regulation of myeloid leukocyte differentiation | 0.0022908 | 57 | 712 | 10 | 0.0140449 | 0.1754386 | GO:BP | ENSG00000019582,ENSG00000159216,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000155846,ENSG00000163823,ENSG00000185650,ENSG00000155090,ENSG00000175104 |
| GO:0071692 | protein localization to extracellular region | 0.0022965 | 638 | 712 | 46 | 0.0646067 | 0.0721003 | GO:BP | ENSG00000004468,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000135077,ENSG00000154451,ENSG00000155657,ENSG00000182054,ENSG00000164111,ENSG00000186470,ENSG00000167461,ENSG00000110090,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000204397,ENSG00000111640,ENSG00000116288,ENSG00000134321,ENSG00000122223,ENSG00000117394,ENSG00000148400,ENSG00000204472,ENSG00000089685,ENSG00000118263,ENSG00000021355,ENSG00000105220,ENSG00000133026,ENSG00000115267,ENSG00000168961,ENSG00000204592,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000111863,ENSG00000096968,ENSG00000170837,ENSG00000165527,ENSG00000127022,ENSG00000102931,ENSG00000254087,ENSG00000139998,ENSG00000155660,ENSG00000028137,ENSG00000175104,ENSG00000110218 |
| GO:0043281 | regulation of cysteine-type endopeptidase activity involved in apoptotic process | 0.0022965 | 221 | 712 | 22 | 0.0308989 | 0.0995475 | GO:BP | ENSG00000126709,ENSG00000117560,ENSG00000117984,ENSG00000138795,ENSG00000232810,ENSG00000204397,ENSG00000116288,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000153094,ENSG00000089685,ENSG00000196954,ENSG00000105220,ENSG00000071994,ENSG00000067560,ENSG00000168961,ENSG00000096968,ENSG00000142867,ENSG00000126432,ENSG00000177076,ENSG00000147889 |
| GO:0042269 | regulation of natural killer cell mediated cytotoxicity | 0.0025361 | 37 | 712 | 8 | 0.0112360 | 0.2162162 | GO:BP | ENSG00000117281,ENSG00000135077,ENSG00000089692,ENSG00000189430,ENSG00000073008,ENSG00000204642,ENSG00000168961,ENSG00000204592 |
| GO:0043370 | regulation of CD4-positive, alpha-beta T cell differentiation | 0.0025361 | 47 | 712 | 9 | 0.0126404 | 0.1914894 | GO:BP | ENSG00000073861,ENSG00000159216,ENSG00000105639,ENSG00000137265,ENSG00000096996,ENSG00000111537,ENSG00000168961,ENSG00000122122,ENSG00000123338 |
| GO:0016043 | cellular component organization | 0.0025361 | 6481 | 712 | 306 | 0.4297753 | 0.0472149 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000196169,ENSG00000148773,ENSG00000119922,ENSG00000204267,ENSG00000113721,ENSG00000196126,ENSG00000183688,ENSG00000007402,ENSG00000229474,ENSG00000248905,ENSG00000072110,ENSG00000129595,ENSG00000156886,ENSG00000117724,ENSG00000157423,ENSG00000100321,ENSG00000179218,ENSG00000126709,ENSG00000184357,ENSG00000147459,ENSG00000154451,ENSG00000100427,ENSG00000080573,ENSG00000155657,ENSG00000163840,ENSG00000123485,ENSG00000231925,ENSG00000019582,ENSG00000117560,ENSG00000198513,ENSG00000159216,ENSG00000160014,ENSG00000034510,ENSG00000173482,ENSG00000130164,ENSG00000069702,ENSG00000091129,ENSG00000221866,ENSG00000101057,ENSG00000163029,ENSG00000170315,ENSG00000166503,ENSG00000156970,ENSG00000171848,ENSG00000125868,ENSG00000125864,ENSG00000117632,ENSG00000169252,ENSG00000160654,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000118193,ENSG00000112029,ENSG00000157216,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000105409,ENSG00000173848,ENSG00000138160,ENSG00000165617,ENSG00000125249,ENSG00000173114,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000112139,ENSG00000232810,ENSG00000183691,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000126787,ENSG00000176293,ENSG00000100749,ENSG00000108179,ENSG00000111640,ENSG00000139626,ENSG00000132646,ENSG00000103769,ENSG00000100380,ENSG00000108518,ENSG00000183741,ENSG00000005844,ENSG00000103148,ENSG00000137474,ENSG00000116288,ENSG00000196230,ENSG00000180644,ENSG00000073008,ENSG00000175793,ENSG00000169855,ENSG00000103966,ENSG00000124575,ENSG00000100918,ENSG00000105011,ENSG00000051341,ENSG00000131018,ENSG00000205413,ENSG00000187446,ENSG00000130402,ENSG00000188312,ENSG00000011426,ENSG00000071205,ENSG00000170312,ENSG00000105887,ENSG00000155846,ENSG00000136436,ENSG00000163359,ENSG00000185651,ENSG00000141576,ENSG00000117394,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000061337,ENSG00000215305,ENSG00000055332,ENSG00000242372,ENSG00000169230,ENSG00000153094,ENSG00000123416,ENSG00000152229,ENSG00000065135,ENSG00000213445,ENSG00000163520,ENSG00000123131,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000163041,ENSG00000044574,ENSG00000124587,ENSG00000171246,ENSG00000130741,ENSG00000116030,ENSG00000118263,ENSG00000064666,ENSG00000072958,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000111229,ENSG00000073803,ENSG00000163545,ENSG00000147065,ENSG00000166974,ENSG00000166454,ENSG00000204899,ENSG00000128578,ENSG00000166197,ENSG00000204822,ENSG00000126016,ENSG00000206127,ENSG00000253626,ENSG00000073910,ENSG00000138071,ENSG00000166598,ENSG00000129007,ENSG00000131236,ENSG00000111348,ENSG00000156234,ENSG00000129675,ENSG00000112031,ENSG00000129534,ENSG00000115155,ENSG00000093009,ENSG00000125871,ENSG00000074800,ENSG00000084623,ENSG00000122952,ENSG00000143228,ENSG00000158869,ENSG00000136717,ENSG00000163131,ENSG00000100385,ENSG00000131504,ENSG00000180574,ENSG00000198821,ENSG00000011485,ENSG00000067560,ENSG00000132932,ENSG00000127952,ENSG00000114166,ENSG00000075340,ENSG00000133026,ENSG00000113810,ENSG00000149294,ENSG00000204256,ENSG00000006625,ENSG00000151466,ENSG00000158882,ENSG00000172270,ENSG00000122877,ENSG00000165283,ENSG00000173517,ENSG00000172795,ENSG00000148175,ENSG00000131747,ENSG00000171617,ENSG00000141736,ENSG00000132963,ENSG00000132182,ENSG00000158321,ENSG00000174371,ENSG00000160877,ENSG00000167286,ENSG00000189369,ENSG00000139579,ENSG00000162676,ENSG00000111863,ENSG00000106462,ENSG00000042753,ENSG00000178996,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000152253,ENSG00000079691,ENSG00000112996,ENSG00000124920,ENSG00000170860,ENSG00000171169,ENSG00000151239,ENSG00000101079,ENSG00000166035,ENSG00000141030,ENSG00000074071,ENSG00000197043,ENSG00000132670,ENSG00000066279,ENSG00000075624,ENSG00000096968,ENSG00000136824,ENSG00000165527,ENSG00000117155,ENSG00000105612,ENSG00000168329,ENSG00000127666,ENSG00000159111,ENSG00000109084,ENSG00000105697,ENSG00000197956,ENSG00000109805,ENSG00000121579,ENSG00000196072,ENSG00000184897,ENSG00000116670,ENSG00000055163,ENSG00000184640,ENSG00000132386,ENSG00000127774,ENSG00000123338,ENSG00000010270,ENSG00000171943,ENSG00000124688,ENSG00000142867,ENSG00000114126,ENSG00000109390,ENSG00000143740,ENSG00000198736,ENSG00000049541,ENSG00000104738,ENSG00000119318,ENSG00000172531,ENSG00000178691,ENSG00000129968,ENSG00000153044,ENSG00000140284,ENSG00000137309,ENSG00000125354,ENSG00000254087,ENSG00000160255,ENSG00000189306,ENSG00000104472,ENSG00000182628,ENSG00000164576,ENSG00000197409,ENSG00000137312,ENSG00000198851,ENSG00000232838,ENSG00000148218,ENSG00000242574,ENSG00000134690,ENSG00000154518,ENSG00000028137,ENSG00000178685,ENSG00000169223,ENSG00000147889,ENSG00000139926,ENSG00000140575,ENSG00000111450,ENSG00000110218,ENSG00000169554,ENSG00000127084,ENSG00000120280,ENSG00000113387,ENSG00000111859 |
| GO:0030036 | actin cytoskeleton organization | 0.0025563 | 679 | 712 | 48 | 0.0674157 | 0.0706922 | GO:BP | ENSG00000113721,ENSG00000183688,ENSG00000248905,ENSG00000072110,ENSG00000129595,ENSG00000179218,ENSG00000155657,ENSG00000034510,ENSG00000125868,ENSG00000117632,ENSG00000196924,ENSG00000150093,ENSG00000136167,ENSG00000125249,ENSG00000172757,ENSG00000232810,ENSG00000108518,ENSG00000130402,ENSG00000011426,ENSG00000105887,ENSG00000155846,ENSG00000204472,ENSG00000064666,ENSG00000111229,ENSG00000163545,ENSG00000126016,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000111348,ENSG00000136717,ENSG00000131504,ENSG00000067560,ENSG00000075340,ENSG00000133026,ENSG00000158321,ENSG00000070831,ENSG00000079691,ENSG00000151239,ENSG00000075624,ENSG00000096968,ENSG00000165527,ENSG00000116670,ENSG00000123338,ENSG00000198736,ENSG00000139926,ENSG00000127084,ENSG00000111859 |
| GO:0035710 | CD4-positive, alpha-beta T cell activation | 0.0026007 | 94 | 712 | 13 | 0.0182584 | 0.1382979 | GO:BP | ENSG00000117281,ENSG00000073861,ENSG00000159216,ENSG00000105639,ENSG00000137265,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000134321,ENSG00000168961,ENSG00000122122,ENSG00000165283,ENSG00000123338 |
| GO:0006323 | DNA packaging | 0.0026414 | 208 | 712 | 21 | 0.0294944 | 0.1009615 | GO:BP | ENSG00000184357,ENSG00000155657,ENSG00000123485,ENSG00000124575,ENSG00000105011,ENSG00000188312,ENSG00000170312,ENSG00000119335,ENSG00000163041,ENSG00000129534,ENSG00000113810,ENSG00000204256,ENSG00000131747,ENSG00000136824,ENSG00000109805,ENSG00000184897,ENSG00000153044,ENSG00000137309,ENSG00000197409,ENSG00000178685,ENSG00000147889 |
| GO:0032940 | secretion by cell | 0.0027285 | 1567 | 712 | 92 | 0.1292135 | 0.0587109 | GO:BP | ENSG00000172057,ENSG00000004468,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000072110,ENSG00000108679,ENSG00000100321,ENSG00000135077,ENSG00000154451,ENSG00000155657,ENSG00000182054,ENSG00000160014,ENSG00000164111,ENSG00000196924,ENSG00000117984,ENSG00000186470,ENSG00000167461,ENSG00000110090,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000204397,ENSG00000111640,ENSG00000103769,ENSG00000005844,ENSG00000116288,ENSG00000196230,ENSG00000134765,ENSG00000134321,ENSG00000137563,ENSG00000187446,ENSG00000130402,ENSG00000122223,ENSG00000117394,ENSG00000213281,ENSG00000123131,ENSG00000148400,ENSG00000041353,ENSG00000204472,ENSG00000089685,ENSG00000118263,ENSG00000064666,ENSG00000072958,ENSG00000166710,ENSG00000163823,ENSG00000138071,ENSG00000131236,ENSG00000021355,ENSG00000115155,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000100299,ENSG00000163131,ENSG00000131504,ENSG00000067560,ENSG00000172794,ENSG00000133026,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000148175,ENSG00000204592,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000111863,ENSG00000153310,ENSG00000171302,ENSG00000147234,ENSG00000096968,ENSG00000170837,ENSG00000165527,ENSG00000139370,ENSG00000127022,ENSG00000102931,ENSG00000123338,ENSG00000143740,ENSG00000140284,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000140319,ENSG00000127951,ENSG00000155660,ENSG00000148218,ENSG00000028137,ENSG00000140575,ENSG00000111450,ENSG00000175104,ENSG00000110218 |
| GO:1903708 | positive regulation of hemopoiesis | 0.0028706 | 194 | 712 | 20 | 0.0280899 | 0.1030928 | GO:BP | ENSG00000019582,ENSG00000159216,ENSG00000115415,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000155846,ENSG00000163823,ENSG00000185650,ENSG00000071994,ENSG00000168421,ENSG00000067560,ENSG00000168961,ENSG00000122122,ENSG00000187608,ENSG00000123338,ENSG00000196839,ENSG00000155090,ENSG00000175104 |
| GO:0045080 | positive regulation of chemokine biosynthetic process | 0.0028706 | 13 | 712 | 5 | 0.0070225 | 0.3846154 | GO:BP | ENSG00000019582,ENSG00000111537,ENSG00000232810,ENSG00000172936,ENSG00000127666 |
| GO:0045595 | regulation of cell differentiation | 0.0028782 | 1932 | 712 | 109 | 0.1530899 | 0.0564182 | GO:BP | ENSG00000004468,ENSG00000176083,ENSG00000183688,ENSG00000092010,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000180739,ENSG00000179218,ENSG00000147459,ENSG00000089692,ENSG00000182054,ENSG00000019582,ENSG00000159216,ENSG00000130164,ENSG00000115415,ENSG00000091129,ENSG00000100911,ENSG00000221866,ENSG00000205336,ENSG00000105639,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000118193,ENSG00000112029,ENSG00000150093,ENSG00000096996,ENSG00000125249,ENSG00000133321,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000232810,ENSG00000183691,ENSG00000117228,ENSG00000183734,ENSG00000134352,ENSG00000103769,ENSG00000175793,ENSG00000169855,ENSG00000204264,ENSG00000130402,ENSG00000170312,ENSG00000155846,ENSG00000185885,ENSG00000141576,ENSG00000061337,ENSG00000055332,ENSG00000242372,ENSG00000169230,ENSG00000159200,ENSG00000148400,ENSG00000163041,ENSG00000044574,ENSG00000118263,ENSG00000166710,ENSG00000073803,ENSG00000163823,ENSG00000138071,ENSG00000185650,ENSG00000136717,ENSG00000071994,ENSG00000168421,ENSG00000067560,ENSG00000132932,ENSG00000127952,ENSG00000114166,ENSG00000213719,ENSG00000185507,ENSG00000168961,ENSG00000122122,ENSG00000171617,ENSG00000141736,ENSG00000213626,ENSG00000187608,ENSG00000162676,ENSG00000106462,ENSG00000070831,ENSG00000079691,ENSG00000151239,ENSG00000066279,ENSG00000096968,ENSG00000176542,ENSG00000079999,ENSG00000165527,ENSG00000168329,ENSG00000105697,ENSG00000116670,ENSG00000132386,ENSG00000123338,ENSG00000171943,ENSG00000178691,ENSG00000041357,ENSG00000254087,ENSG00000091127,ENSG00000127951,ENSG00000197409,ENSG00000137312,ENSG00000196839,ENSG00000155090,ENSG00000028137,ENSG00000147889,ENSG00000140575,ENSG00000175104,ENSG00000169554,ENSG00000111859 |
| GO:0061756 | leukocyte adhesion to vascular endothelial cell | 0.0029002 | 48 | 712 | 9 | 0.0126404 | 0.1875000 | GO:BP | ENSG00000150093,ENSG00000232810,ENSG00000139626,ENSG00000067560,ENSG00000075340,ENSG00000168329,ENSG00000160255,ENSG00000175104,ENSG00000114631 |
| GO:0002790 | peptide secretion | 0.0030511 | 666 | 712 | 47 | 0.0660112 | 0.0705706 | GO:BP | ENSG00000004468,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000135077,ENSG00000154451,ENSG00000155657,ENSG00000182054,ENSG00000019582,ENSG00000164111,ENSG00000186470,ENSG00000167461,ENSG00000110090,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000204397,ENSG00000111640,ENSG00000116288,ENSG00000134321,ENSG00000122223,ENSG00000117394,ENSG00000148400,ENSG00000204472,ENSG00000089685,ENSG00000118263,ENSG00000021355,ENSG00000105220,ENSG00000133026,ENSG00000115267,ENSG00000168961,ENSG00000204592,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000111863,ENSG00000096968,ENSG00000170837,ENSG00000165527,ENSG00000127022,ENSG00000102931,ENSG00000254087,ENSG00000139998,ENSG00000155660,ENSG00000028137,ENSG00000175104,ENSG00000110218 |
| GO:0042108 | positive regulation of cytokine biosynthetic process | 0.0030894 | 71 | 712 | 11 | 0.0154494 | 0.1549296 | GO:BP | ENSG00000125347,ENSG00000019582,ENSG00000137265,ENSG00000111537,ENSG00000232810,ENSG00000172936,ENSG00000096968,ENSG00000127666,ENSG00000142867,ENSG00000198851,ENSG00000175104 |
| GO:0140352 | export from cell | 0.0030957 | 1616 | 712 | 94 | 0.1320225 | 0.0581683 | GO:BP | ENSG00000172057,ENSG00000004468,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000072110,ENSG00000108679,ENSG00000100321,ENSG00000135077,ENSG00000154451,ENSG00000155657,ENSG00000182054,ENSG00000160014,ENSG00000164111,ENSG00000196924,ENSG00000117984,ENSG00000186470,ENSG00000167461,ENSG00000105409,ENSG00000110090,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000204397,ENSG00000111640,ENSG00000118777,ENSG00000103769,ENSG00000005844,ENSG00000116288,ENSG00000196230,ENSG00000134765,ENSG00000134321,ENSG00000137563,ENSG00000187446,ENSG00000130402,ENSG00000122223,ENSG00000117394,ENSG00000213281,ENSG00000123131,ENSG00000148400,ENSG00000041353,ENSG00000204472,ENSG00000089685,ENSG00000118263,ENSG00000064666,ENSG00000072958,ENSG00000166710,ENSG00000163823,ENSG00000138071,ENSG00000131236,ENSG00000021355,ENSG00000115155,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000100299,ENSG00000163131,ENSG00000131504,ENSG00000067560,ENSG00000172794,ENSG00000133026,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000148175,ENSG00000204592,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000111863,ENSG00000153310,ENSG00000171302,ENSG00000147234,ENSG00000096968,ENSG00000170837,ENSG00000165527,ENSG00000139370,ENSG00000127022,ENSG00000102931,ENSG00000123338,ENSG00000143740,ENSG00000140284,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000140319,ENSG00000127951,ENSG00000155660,ENSG00000148218,ENSG00000028137,ENSG00000140575,ENSG00000111450,ENSG00000175104,ENSG00000110218 |
| GO:0080134 | regulation of response to stress | 0.0030988 | 1574 | 712 | 92 | 0.1292135 | 0.0584498 | GO:BP | ENSG00000138496,ENSG00000117281,ENSG00000092010,ENSG00000125347,ENSG00000135077,ENSG00000154451,ENSG00000100427,ENSG00000163840,ENSG00000089692,ENSG00000019582,ENSG00000130164,ENSG00000115415,ENSG00000155629,ENSG00000100911,ENSG00000164111,ENSG00000170315,ENSG00000137265,ENSG00000112029,ENSG00000123609,ENSG00000096996,ENSG00000165617,ENSG00000125249,ENSG00000111206,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000134352,ENSG00000132646,ENSG00000116288,ENSG00000111602,ENSG00000073008,ENSG00000134321,ENSG00000156463,ENSG00000204264,ENSG00000051341,ENSG00000077984,ENSG00000164830,ENSG00000055332,ENSG00000239713,ENSG00000153094,ENSG00000213281,ENSG00000044574,ENSG00000116030,ENSG00000166710,ENSG00000073803,ENSG00000185745,ENSG00000180667,ENSG00000138071,ENSG00000166598,ENSG00000196954,ENSG00000074800,ENSG00000158869,ENSG00000013725,ENSG00000163131,ENSG00000197417,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000204592,ENSG00000132182,ENSG00000162676,ENSG00000111863,ENSG00000070831,ENSG00000172936,ENSG00000178719,ENSG00000054965,ENSG00000096968,ENSG00000164164,ENSG00000128394,ENSG00000127666,ENSG00000125648,ENSG00000116670,ENSG00000132386,ENSG00000128272,ENSG00000142867,ENSG00000138646,ENSG00000137309,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000127951,ENSG00000137312,ENSG00000196839,ENSG00000136104,ENSG00000135960,ENSG00000028137,ENSG00000132256,ENSG00000147889,ENSG00000175104,ENSG00000169554,ENSG00000170485 |
| GO:1902107 | positive regulation of leukocyte differentiation | 0.0031214 | 151 | 712 | 17 | 0.0238764 | 0.1125828 | GO:BP | ENSG00000019582,ENSG00000159216,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000155846,ENSG00000163823,ENSG00000185650,ENSG00000168421,ENSG00000067560,ENSG00000168961,ENSG00000122122,ENSG00000123338,ENSG00000196839,ENSG00000155090,ENSG00000175104 |
| GO:0060548 | negative regulation of cell death | 0.0031552 | 1039 | 712 | 66 | 0.0926966 | 0.0635226 | GO:BP | ENSG00000004468,ENSG00000113721,ENSG00000126709,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000119917,ENSG00000164111,ENSG00000170315,ENSG00000105639,ENSG00000196924,ENSG00000118193,ENSG00000150093,ENSG00000172757,ENSG00000138795,ENSG00000232810,ENSG00000183691,ENSG00000204397,ENSG00000108179,ENSG00000134352,ENSG00000116288,ENSG00000249437,ENSG00000175793,ENSG00000156463,ENSG00000071205,ENSG00000170312,ENSG00000164830,ENSG00000141576,ENSG00000070018,ENSG00000055332,ENSG00000169230,ENSG00000065135,ENSG00000119335,ENSG00000148400,ENSG00000204472,ENSG00000089685,ENSG00000044574,ENSG00000163545,ENSG00000166598,ENSG00000118971,ENSG00000074800,ENSG00000105220,ENSG00000158869,ENSG00000158006,ENSG00000100385,ENSG00000011485,ENSG00000067560,ENSG00000185507,ENSG00000204642,ENSG00000103495,ENSG00000104765,ENSG00000172936,ENSG00000178719,ENSG00000096968,ENSG00000168329,ENSG00000138617,ENSG00000132386,ENSG00000123338,ENSG00000128272,ENSG00000142867,ENSG00000126432,ENSG00000196839,ENSG00000028137,ENSG00000137193,ENSG00000175104,ENSG00000170485 |
| GO:0042221 | response to chemical | 0.0032484 | 4897 | 712 | 239 | 0.3356742 | 0.0488054 | GO:BP | ENSG00000004468,ENSG00000179344,ENSG00000119922,ENSG00000138496,ENSG00000113721,ENSG00000196126,ENSG00000092010,ENSG00000073861,ENSG00000132530,ENSG00000117724,ENSG00000125347,ENSG00000100321,ENSG00000109956,ENSG00000179218,ENSG00000126709,ENSG00000159674,ENSG00000135077,ENSG00000092068,ENSG00000154451,ENSG00000162654,ENSG00000100427,ENSG00000134184,ENSG00000155657,ENSG00000196735,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000072135,ENSG00000159216,ENSG00000151502,ENSG00000160014,ENSG00000173482,ENSG00000130164,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000186469,ENSG00000069702,ENSG00000091129,ENSG00000100911,ENSG00000221866,ENSG00000164111,ENSG00000113368,ENSG00000101057,ENSG00000177156,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000142089,ENSG00000169252,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000120057,ENSG00000127947,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000105409,ENSG00000123609,ENSG00000173848,ENSG00000096996,ENSG00000125249,ENSG00000172757,ENSG00000138795,ENSG00000110090,ENSG00000111537,ENSG00000102554,ENSG00000099194,ENSG00000232810,ENSG00000183691,ENSG00000117228,ENSG00000176890,ENSG00000204397,ENSG00000108179,ENSG00000111640,ENSG00000118777,ENSG00000134352,ENSG00000132646,ENSG00000117226,ENSG00000185201,ENSG00000116288,ENSG00000111602,ENSG00000135114,ENSG00000134321,ENSG00000169855,ENSG00000103966,ENSG00000023572,ENSG00000137563,ENSG00000204264,ENSG00000188191,ENSG00000130402,ENSG00000170312,ENSG00000155846,ENSG00000136436,ENSG00000185885,ENSG00000185651,ENSG00000164830,ENSG00000117394,ENSG00000070018,ENSG00000165949,ENSG00000055332,ENSG00000242372,ENSG00000153094,ENSG00000123416,ENSG00000065135,ENSG00000213445,ENSG00000104687,ENSG00000123131,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000152256,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000044574,ENSG00000116030,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000111229,ENSG00000104805,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000180667,ENSG00000129422,ENSG00000126016,ENSG00000138071,ENSG00000166598,ENSG00000148730,ENSG00000156234,ENSG00000196954,ENSG00000101444,ENSG00000185650,ENSG00000111331,ENSG00000074800,ENSG00000105220,ENSG00000158869,ENSG00000100299,ENSG00000013725,ENSG00000163131,ENSG00000170881,ENSG00000100385,ENSG00000125148,ENSG00000131504,ENSG00000011485,ENSG00000067560,ENSG00000197417,ENSG00000213928,ENSG00000114166,ENSG00000165304,ENSG00000134202,ENSG00000133026,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000115339,ENSG00000172270,ENSG00000122877,ENSG00000141736,ENSG00000204592,ENSG00000103994,ENSG00000213626,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000162676,ENSG00000111863,ENSG00000106462,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000118705,ENSG00000179583,ENSG00000132670,ENSG00000075624,ENSG00000096968,ENSG00000164164,ENSG00000075239,ENSG00000079999,ENSG00000170837,ENSG00000165527,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000139370,ENSG00000105697,ENSG00000127022,ENSG00000148908,ENSG00000138617,ENSG00000125648,ENSG00000055163,ENSG00000090520,ENSG00000132386,ENSG00000049239,ENSG00000256436,ENSG00000123338,ENSG00000128272,ENSG00000142867,ENSG00000111335,ENSG00000126432,ENSG00000119318,ENSG00000172531,ENSG00000168765,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000213366,ENSG00000140319,ENSG00000177076,ENSG00000197409,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000143321,ENSG00000155090,ENSG00000148218,ENSG00000147168,ENSG00000177674,ENSG00000135960,ENSG00000028137,ENSG00000132256,ENSG00000140575,ENSG00000137193,ENSG00000111450,ENSG00000175104,ENSG00000110218,ENSG00000170485,ENSG00000112759,ENSG00000081985 |
| GO:0045058 | T cell selection | 0.0033217 | 49 | 712 | 9 | 0.0126404 | 0.1836735 | GO:BP | ENSG00000073861,ENSG00000019582,ENSG00000160654,ENSG00000137265,ENSG00000096996,ENSG00000184916,ENSG00000067560,ENSG00000167286,ENSG00000198851 |
| GO:0045639 | positive regulation of myeloid cell differentiation | 0.0033976 | 97 | 712 | 13 | 0.0182584 | 0.1340206 | GO:BP | ENSG00000019582,ENSG00000159216,ENSG00000115415,ENSG00000138795,ENSG00000111537,ENSG00000232810,ENSG00000155846,ENSG00000163823,ENSG00000185650,ENSG00000187608,ENSG00000123338,ENSG00000155090,ENSG00000175104 |
| GO:0001916 | positive regulation of T cell mediated cytotoxicity | 0.0035485 | 21 | 712 | 6 | 0.0084270 | 0.2857143 | GO:BP | ENSG00000096996,ENSG00000073008,ENSG00000166710,ENSG00000204642,ENSG00000204592,ENSG00000153310 |
| GO:0035455 | response to interferon-alpha | 0.0035485 | 21 | 712 | 6 | 0.0084270 | 0.2857143 | GO:BP | ENSG00000119922,ENSG00000119917,ENSG00000142089,ENSG00000185201,ENSG00000185885,ENSG00000055332 |
| GO:0052548 | regulation of endopeptidase activity | 0.0036984 | 433 | 712 | 34 | 0.0477528 | 0.0785219 | GO:BP | ENSG00000092010,ENSG00000126709,ENSG00000117560,ENSG00000100911,ENSG00000117984,ENSG00000138795,ENSG00000232810,ENSG00000204397,ENSG00000111640,ENSG00000116288,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000204264,ENSG00000077984,ENSG00000163359,ENSG00000169230,ENSG00000153094,ENSG00000089685,ENSG00000021355,ENSG00000196954,ENSG00000105220,ENSG00000136717,ENSG00000071994,ENSG00000067560,ENSG00000168961,ENSG00000096968,ENSG00000055163,ENSG00000132386,ENSG00000142867,ENSG00000126432,ENSG00000254087,ENSG00000177076,ENSG00000147889 |
| GO:0051094 | positive regulation of developmental process | 0.0036984 | 1457 | 712 | 86 | 0.1207865 | 0.0590254 | GO:BP | ENSG00000113721,ENSG00000007402,ENSG00000073861,ENSG00000179218,ENSG00000147459,ENSG00000019582,ENSG00000159216,ENSG00000115415,ENSG00000069702,ENSG00000091129,ENSG00000221866,ENSG00000169252,ENSG00000196924,ENSG00000146674,ENSG00000112029,ENSG00000157216,ENSG00000150093,ENSG00000096996,ENSG00000173114,ENSG00000133321,ENSG00000138795,ENSG00000111537,ENSG00000102554,ENSG00000232810,ENSG00000183691,ENSG00000134352,ENSG00000103769,ENSG00000175793,ENSG00000169855,ENSG00000077984,ENSG00000170312,ENSG00000155846,ENSG00000185885,ENSG00000141576,ENSG00000139182,ENSG00000171603,ENSG00000148400,ENSG00000044574,ENSG00000166710,ENSG00000073803,ENSG00000163823,ENSG00000126016,ENSG00000138071,ENSG00000185650,ENSG00000136717,ENSG00000071994,ENSG00000168421,ENSG00000067560,ENSG00000132932,ENSG00000127952,ENSG00000213719,ENSG00000168961,ENSG00000122122,ENSG00000171617,ENSG00000213626,ENSG00000187608,ENSG00000106462,ENSG00000070831,ENSG00000079691,ENSG00000124920,ENSG00000151239,ENSG00000066279,ENSG00000096968,ENSG00000168329,ENSG00000105697,ENSG00000223496,ENSG00000116670,ENSG00000132386,ENSG00000123338,ENSG00000171943,ENSG00000128272,ENSG00000137309,ENSG00000254087,ENSG00000160255,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000155090,ENSG00000028137,ENSG00000147889,ENSG00000140575,ENSG00000137193,ENSG00000175104,ENSG00000169554,ENSG00000166794,ENSG00000111859 |
| GO:2000514 | regulation of CD4-positive, alpha-beta T cell activation | 0.0037046 | 61 | 712 | 10 | 0.0140449 | 0.1639344 | GO:BP | ENSG00000117281,ENSG00000073861,ENSG00000159216,ENSG00000105639,ENSG00000137265,ENSG00000096996,ENSG00000111537,ENSG00000168961,ENSG00000122122,ENSG00000123338 |
| GO:0032879 | regulation of localization | 0.0037046 | 2942 | 712 | 154 | 0.2162921 | 0.0523453 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000138496,ENSG00000113721,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000072110,ENSG00000179218,ENSG00000135077,ENSG00000147459,ENSG00000100427,ENSG00000155657,ENSG00000163840,ENSG00000182054,ENSG00000019582,ENSG00000117560,ENSG00000160014,ENSG00000034510,ENSG00000173482,ENSG00000069702,ENSG00000221866,ENSG00000205336,ENSG00000164111,ENSG00000117632,ENSG00000169252,ENSG00000196924,ENSG00000146674,ENSG00000118193,ENSG00000112029,ENSG00000117984,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000125249,ENSG00000138795,ENSG00000110090,ENSG00000111537,ENSG00000179051,ENSG00000232810,ENSG00000183691,ENSG00000117228,ENSG00000134308,ENSG00000204397,ENSG00000108179,ENSG00000111640,ENSG00000103769,ENSG00000108518,ENSG00000116288,ENSG00000134321,ENSG00000175793,ENSG00000169855,ENSG00000103966,ENSG00000156463,ENSG00000188191,ENSG00000187446,ENSG00000130402,ENSG00000170312,ENSG00000122223,ENSG00000185885,ENSG00000185651,ENSG00000117394,ENSG00000139182,ENSG00000165949,ENSG00000215305,ENSG00000169230,ENSG00000148400,ENSG00000041353,ENSG00000167723,ENSG00000204472,ENSG00000089685,ENSG00000044574,ENSG00000116030,ENSG00000118263,ENSG00000064666,ENSG00000132274,ENSG00000166710,ENSG00000104805,ENSG00000163823,ENSG00000147065,ENSG00000166974,ENSG00000180667,ENSG00000129422,ENSG00000166197,ENSG00000126016,ENSG00000111348,ENSG00000156234,ENSG00000108798,ENSG00000021355,ENSG00000185650,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000196449,ENSG00000136717,ENSG00000163131,ENSG00000170881,ENSG00000100385,ENSG00000131504,ENSG00000198821,ENSG00000067560,ENSG00000132932,ENSG00000213719,ENSG00000133026,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000172795,ENSG00000148175,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000198843,ENSG00000103495,ENSG00000111863,ENSG00000042753,ENSG00000104765,ENSG00000070831,ENSG00000079691,ENSG00000172936,ENSG00000197043,ENSG00000075624,ENSG00000096968,ENSG00000170837,ENSG00000165527,ENSG00000117155,ENSG00000168329,ENSG00000105697,ENSG00000102931,ENSG00000125648,ENSG00000132386,ENSG00000123338,ENSG00000171943,ENSG00000128272,ENSG00000111335,ENSG00000114126,ENSG00000129968,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000213366,ENSG00000150756,ENSG00000137312,ENSG00000196839,ENSG00000147168,ENSG00000028137,ENSG00000169223,ENSG00000132256,ENSG00000140575,ENSG00000137193,ENSG00000155096,ENSG00000175104,ENSG00000110218,ENSG00000111859 |
| GO:1901698 | response to nitrogen compound | 0.0037097 | 1168 | 712 | 72 | 0.1011236 | 0.0616438 | GO:BP | ENSG00000134184,ENSG00000160014,ENSG00000130164,ENSG00000115415,ENSG00000186469,ENSG00000069702,ENSG00000164111,ENSG00000105639,ENSG00000169252,ENSG00000196924,ENSG00000150093,ENSG00000167461,ENSG00000105409,ENSG00000172757,ENSG00000102554,ENSG00000232810,ENSG00000176890,ENSG00000132646,ENSG00000111602,ENSG00000137563,ENSG00000188191,ENSG00000170312,ENSG00000155846,ENSG00000117394,ENSG00000070018,ENSG00000242372,ENSG00000153094,ENSG00000065135,ENSG00000148400,ENSG00000204472,ENSG00000171130,ENSG00000044574,ENSG00000185745,ENSG00000180667,ENSG00000138071,ENSG00000166598,ENSG00000148730,ENSG00000196954,ENSG00000185650,ENSG00000105220,ENSG00000158869,ENSG00000170881,ENSG00000131504,ENSG00000011485,ENSG00000067560,ENSG00000114166,ENSG00000134202,ENSG00000115267,ENSG00000172270,ENSG00000122877,ENSG00000103994,ENSG00000111863,ENSG00000106462,ENSG00000172936,ENSG00000179583,ENSG00000132670,ENSG00000075624,ENSG00000096968,ENSG00000162104,ENSG00000127666,ENSG00000148908,ENSG00000128272,ENSG00000254087,ENSG00000160255,ENSG00000213366,ENSG00000137312,ENSG00000196839,ENSG00000155090,ENSG00000148218,ENSG00000177674,ENSG00000140575,ENSG00000110218 |
| GO:0051128 | regulation of cellular component organization | 0.0037788 | 2541 | 712 | 136 | 0.1910112 | 0.0535222 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000148773,ENSG00000113721,ENSG00000229474,ENSG00000248905,ENSG00000117724,ENSG00000179218,ENSG00000184357,ENSG00000147459,ENSG00000154451,ENSG00000123485,ENSG00000159216,ENSG00000160014,ENSG00000034510,ENSG00000130164,ENSG00000091129,ENSG00000221866,ENSG00000166503,ENSG00000156970,ENSG00000125868,ENSG00000117632,ENSG00000169252,ENSG00000196924,ENSG00000146674,ENSG00000118193,ENSG00000112029,ENSG00000136167,ENSG00000173848,ENSG00000138160,ENSG00000165617,ENSG00000125249,ENSG00000173114,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000112139,ENSG00000232810,ENSG00000117228,ENSG00000134308,ENSG00000126787,ENSG00000176293,ENSG00000108179,ENSG00000103769,ENSG00000108518,ENSG00000103148,ENSG00000116288,ENSG00000196230,ENSG00000175793,ENSG00000169855,ENSG00000103966,ENSG00000124575,ENSG00000130402,ENSG00000011426,ENSG00000105887,ENSG00000136436,ENSG00000185651,ENSG00000141576,ENSG00000139182,ENSG00000171603,ENSG00000061337,ENSG00000215305,ENSG00000055332,ENSG00000169230,ENSG00000153094,ENSG00000213445,ENSG00000119335,ENSG00000148400,ENSG00000163041,ENSG00000044574,ENSG00000116030,ENSG00000166710,ENSG00000111229,ENSG00000073803,ENSG00000147065,ENSG00000166974,ENSG00000166454,ENSG00000128578,ENSG00000253626,ENSG00000138071,ENSG00000111348,ENSG00000156234,ENSG00000093009,ENSG00000074800,ENSG00000136717,ENSG00000131504,ENSG00000067560,ENSG00000132932,ENSG00000127952,ENSG00000114166,ENSG00000075340,ENSG00000133026,ENSG00000173517,ENSG00000172795,ENSG00000131747,ENSG00000171617,ENSG00000141736,ENSG00000158321,ENSG00000139579,ENSG00000162676,ENSG00000111863,ENSG00000106462,ENSG00000042753,ENSG00000104765,ENSG00000070831,ENSG00000079691,ENSG00000171169,ENSG00000151239,ENSG00000101079,ENSG00000165527,ENSG00000127666,ENSG00000109084,ENSG00000105697,ENSG00000184897,ENSG00000116670,ENSG00000184640,ENSG00000132386,ENSG00000123338,ENSG00000171943,ENSG00000124688,ENSG00000114126,ENSG00000129968,ENSG00000137309,ENSG00000254087,ENSG00000160255,ENSG00000182628,ENSG00000137312,ENSG00000028137,ENSG00000178685,ENSG00000147889,ENSG00000140575,ENSG00000169554,ENSG00000127084,ENSG00000111859 |
| GO:0010942 | positive regulation of cell death | 0.0038144 | 751 | 712 | 51 | 0.0716292 | 0.0679095 | GO:BP | ENSG00000100453,ENSG00000119922,ENSG00000113721,ENSG00000117281,ENSG00000163599,ENSG00000117560,ENSG00000164111,ENSG00000101057,ENSG00000170315,ENSG00000167004,ENSG00000146674,ENSG00000117984,ENSG00000150093,ENSG00000173848,ENSG00000111537,ENSG00000232810,ENSG00000134308,ENSG00000108179,ENSG00000111640,ENSG00000116288,ENSG00000175793,ENSG00000169855,ENSG00000169230,ENSG00000153094,ENSG00000148400,ENSG00000129675,ENSG00000196954,ENSG00000145649,ENSG00000136717,ENSG00000071994,ENSG00000067560,ENSG00000127952,ENSG00000165304,ENSG00000168961,ENSG00000131747,ENSG00000132792,ENSG00000104765,ENSG00000070831,ENSG00000096968,ENSG00000128272,ENSG00000142867,ENSG00000114126,ENSG00000172531,ENSG00000254087,ENSG00000160255,ENSG00000177076,ENSG00000172667,ENSG00000028137,ENSG00000147889,ENSG00000175104,ENSG00000127084 |
| GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | 0.0038215 | 184 | 712 | 19 | 0.0266854 | 0.1032609 | GO:BP | ENSG00000019582,ENSG00000117560,ENSG00000196924,ENSG00000232810,ENSG00000204397,ENSG00000128284,ENSG00000132274,ENSG00000152778,ENSG00000011485,ENSG00000067560,ENSG00000168961,ENSG00000172936,ENSG00000171302,ENSG00000168329,ENSG00000127666,ENSG00000142867,ENSG00000135960,ENSG00000132256,ENSG00000175104 |
| GO:0007162 | negative regulation of cell adhesion | 0.0040283 | 297 | 712 | 26 | 0.0365169 | 0.0875421 | GO:BP | ENSG00000196126,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000221866,ENSG00000105639,ENSG00000179051,ENSG00000117228,ENSG00000130402,ENSG00000213445,ENSG00000148400,ENSG00000111348,ENSG00000067560,ENSG00000168961,ENSG00000141736,ENSG00000157873,ENSG00000111863,ENSG00000096968,ENSG00000116670,ENSG00000177076,ENSG00000127951,ENSG00000147889 |
| GO:0051250 | negative regulation of lymphocyte activation | 0.0040412 | 155 | 712 | 17 | 0.0238764 | 0.1096774 | GO:BP | ENSG00000196126,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000105639,ENSG00000204642,ENSG00000168961,ENSG00000141736,ENSG00000157873,ENSG00000254087,ENSG00000127951,ENSG00000101082,ENSG00000147889 |
| GO:0000280 | nuclear division | 0.0040412 | 418 | 712 | 33 | 0.0463483 | 0.0789474 | GO:BP | ENSG00000148773,ENSG00000113721,ENSG00000117724,ENSG00000179218,ENSG00000155657,ENSG00000101057,ENSG00000170315,ENSG00000156970,ENSG00000196924,ENSG00000118193,ENSG00000112029,ENSG00000138160,ENSG00000126787,ENSG00000103769,ENSG00000100918,ENSG00000011426,ENSG00000153094,ENSG00000089685,ENSG00000204899,ENSG00000138071,ENSG00000122952,ENSG00000143228,ENSG00000067560,ENSG00000113810,ENSG00000131747,ENSG00000070831,ENSG00000066279,ENSG00000136824,ENSG00000109805,ENSG00000121579,ENSG00000116670,ENSG00000124688,ENSG00000134690 |
| GO:1901701 | cellular response to oxygen-containing compound | 0.0041377 | 1235 | 712 | 75 | 0.1053371 | 0.0607287 | GO:BP | ENSG00000113721,ENSG00000196126,ENSG00000159674,ENSG00000135077,ENSG00000100427,ENSG00000130164,ENSG00000115415,ENSG00000186469,ENSG00000164111,ENSG00000105639,ENSG00000169252,ENSG00000196924,ENSG00000167461,ENSG00000105409,ENSG00000173848,ENSG00000110090,ENSG00000102554,ENSG00000232810,ENSG00000204397,ENSG00000108179,ENSG00000132646,ENSG00000116288,ENSG00000111602,ENSG00000023572,ENSG00000188191,ENSG00000170312,ENSG00000155846,ENSG00000164830,ENSG00000070018,ENSG00000153094,ENSG00000065135,ENSG00000213445,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000044574,ENSG00000118263,ENSG00000147065,ENSG00000138071,ENSG00000166598,ENSG00000148730,ENSG00000156234,ENSG00000196954,ENSG00000185650,ENSG00000013725,ENSG00000011485,ENSG00000067560,ENSG00000197417,ENSG00000114166,ENSG00000103994,ENSG00000198843,ENSG00000162676,ENSG00000106462,ENSG00000172936,ENSG00000132670,ENSG00000075624,ENSG00000096968,ENSG00000170837,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000105697,ENSG00000148908,ENSG00000132386,ENSG00000128272,ENSG00000142867,ENSG00000126432,ENSG00000254087,ENSG00000155090,ENSG00000177674,ENSG00000028137,ENSG00000132256,ENSG00000137193,ENSG00000175104,ENSG00000112759 |
| GO:0045055 | regulated exocytosis | 0.0041377 | 793 | 712 | 53 | 0.0744382 | 0.0668348 | GO:BP | ENSG00000172057,ENSG00000072110,ENSG00000108679,ENSG00000100321,ENSG00000155657,ENSG00000160014,ENSG00000164111,ENSG00000196924,ENSG00000117984,ENSG00000005844,ENSG00000196230,ENSG00000134765,ENSG00000137563,ENSG00000187446,ENSG00000130402,ENSG00000213281,ENSG00000123131,ENSG00000148400,ENSG00000041353,ENSG00000064666,ENSG00000072958,ENSG00000166710,ENSG00000138071,ENSG00000131236,ENSG00000021355,ENSG00000115155,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000100299,ENSG00000163131,ENSG00000131504,ENSG00000067560,ENSG00000172794,ENSG00000204642,ENSG00000168961,ENSG00000148175,ENSG00000153310,ENSG00000171302,ENSG00000147234,ENSG00000139370,ENSG00000123338,ENSG00000143740,ENSG00000140284,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000140319,ENSG00000127951,ENSG00000148218,ENSG00000028137,ENSG00000140575,ENSG00000111450 |
| GO:0032069 | regulation of nuclease activity | 0.0044742 | 22 | 712 | 6 | 0.0084270 | 0.2727273 | GO:BP | ENSG00000132646,ENSG00000135114,ENSG00000089127,ENSG00000111331,ENSG00000145649,ENSG00000111335 |
| GO:0002695 | negative regulation of leukocyte activation | 0.0046046 | 187 | 712 | 19 | 0.0266854 | 0.1016043 | GO:BP | ENSG00000196126,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000130164,ENSG00000105639,ENSG00000077984,ENSG00000204642,ENSG00000168961,ENSG00000141736,ENSG00000157873,ENSG00000254087,ENSG00000127951,ENSG00000101082,ENSG00000147889 |
| GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 0.0046354 | 75 | 712 | 11 | 0.0154494 | 0.1466667 | GO:BP | ENSG00000204267,ENSG00000092010,ENSG00000179218,ENSG00000231925,ENSG00000100911,ENSG00000167004,ENSG00000204264,ENSG00000166710,ENSG00000204642,ENSG00000204592,ENSG00000041357 |
| GO:0002444 | myeloid leukocyte mediated immunity | 0.0046354 | 549 | 712 | 40 | 0.0561798 | 0.0728597 | GO:BP | ENSG00000172057,ENSG00000100321,ENSG00000159674,ENSG00000117984,ENSG00000005844,ENSG00000196230,ENSG00000134765,ENSG00000137563,ENSG00000213281,ENSG00000123131,ENSG00000064666,ENSG00000072958,ENSG00000166710,ENSG00000138071,ENSG00000131236,ENSG00000021355,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000100299,ENSG00000163131,ENSG00000131504,ENSG00000067560,ENSG00000172794,ENSG00000168961,ENSG00000148175,ENSG00000204592,ENSG00000171302,ENSG00000147234,ENSG00000127666,ENSG00000139370,ENSG00000123338,ENSG00000140284,ENSG00000254087,ENSG00000160255,ENSG00000140319,ENSG00000127951,ENSG00000148218,ENSG00000028137,ENSG00000140575 |
| GO:0002715 | regulation of natural killer cell mediated immunity | 0.0047074 | 41 | 712 | 8 | 0.0112360 | 0.1951220 | GO:BP | ENSG00000117281,ENSG00000135077,ENSG00000089692,ENSG00000189430,ENSG00000073008,ENSG00000204642,ENSG00000168961,ENSG00000204592 |
| GO:0019985 | translesion synthesis | 0.0047074 | 41 | 712 | 8 | 0.0112360 | 0.1951220 | GO:BP | ENSG00000156587,ENSG00000170315,ENSG00000132646,ENSG00000143476,ENSG00000187608,ENSG00000116670,ENSG00000049541,ENSG00000178685 |
| GO:0043367 | CD4-positive, alpha-beta T cell differentiation | 0.0051723 | 76 | 712 | 11 | 0.0154494 | 0.1447368 | GO:BP | ENSG00000073861,ENSG00000159216,ENSG00000105639,ENSG00000137265,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000134321,ENSG00000168961,ENSG00000122122,ENSG00000123338 |
| GO:0015031 | protein transport | 0.0052567 | 2121 | 712 | 116 | 0.1629213 | 0.0546912 | GO:BP | ENSG00000004468,ENSG00000204267,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000117724,ENSG00000100321,ENSG00000179218,ENSG00000135077,ENSG00000154451,ENSG00000100427,ENSG00000155657,ENSG00000163840,ENSG00000182054,ENSG00000019582,ENSG00000151502,ENSG00000164111,ENSG00000170315,ENSG00000160654,ENSG00000196924,ENSG00000186470,ENSG00000136167,ENSG00000167461,ENSG00000110090,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000134308,ENSG00000204397,ENSG00000111640,ENSG00000103769,ENSG00000189319,ENSG00000137474,ENSG00000116288,ENSG00000134321,ENSG00000175793,ENSG00000143742,ENSG00000136274,ENSG00000187446,ENSG00000130402,ENSG00000170312,ENSG00000122223,ENSG00000185651,ENSG00000117394,ENSG00000171603,ENSG00000165949,ENSG00000185304,ENSG00000152969,ENSG00000215305,ENSG00000242372,ENSG00000148400,ENSG00000157601,ENSG00000041353,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000044574,ENSG00000124587,ENSG00000118263,ENSG00000072958,ENSG00000104805,ENSG00000185745,ENSG00000180667,ENSG00000166197,ENSG00000253626,ENSG00000166598,ENSG00000157985,ENSG00000132661,ENSG00000021355,ENSG00000172803,ENSG00000105220,ENSG00000213064,ENSG00000172794,ENSG00000133026,ENSG00000115267,ENSG00000168961,ENSG00000158882,ENSG00000122877,ENSG00000148175,ENSG00000141736,ENSG00000204592,ENSG00000132182,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000111863,ENSG00000042753,ENSG00000178996,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000096968,ENSG00000170837,ENSG00000165527,ENSG00000117155,ENSG00000162385,ENSG00000139370,ENSG00000127022,ENSG00000102931,ENSG00000140450,ENSG00000120709,ENSG00000143740,ENSG00000140284,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000140319,ENSG00000155660,ENSG00000172667,ENSG00000184575,ENSG00000028137,ENSG00000169223,ENSG00000111481,ENSG00000111450,ENSG00000175104,ENSG00000110218 |
| GO:0044085 | cellular component biogenesis | 0.0053306 | 3241 | 712 | 166 | 0.2331461 | 0.0512188 | GO:BP | ENSG00000172057,ENSG00000113721,ENSG00000196126,ENSG00000229474,ENSG00000248905,ENSG00000072110,ENSG00000117724,ENSG00000157423,ENSG00000179218,ENSG00000184357,ENSG00000154451,ENSG00000100427,ENSG00000155657,ENSG00000123485,ENSG00000231925,ENSG00000019582,ENSG00000198513,ENSG00000159216,ENSG00000034510,ENSG00000069702,ENSG00000091129,ENSG00000101057,ENSG00000170315,ENSG00000166503,ENSG00000171848,ENSG00000117632,ENSG00000169252,ENSG00000160654,ENSG00000196924,ENSG00000118193,ENSG00000112029,ENSG00000157216,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000138160,ENSG00000165617,ENSG00000125249,ENSG00000173114,ENSG00000138795,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000112139,ENSG00000232810,ENSG00000117228,ENSG00000103769,ENSG00000100380,ENSG00000108518,ENSG00000103148,ENSG00000137474,ENSG00000116288,ENSG00000196230,ENSG00000180644,ENSG00000103966,ENSG00000124575,ENSG00000100918,ENSG00000105011,ENSG00000051341,ENSG00000187446,ENSG00000130402,ENSG00000188312,ENSG00000011426,ENSG00000170312,ENSG00000105887,ENSG00000117394,ENSG00000139182,ENSG00000171603,ENSG00000215305,ENSG00000055332,ENSG00000242372,ENSG00000153094,ENSG00000119335,ENSG00000148400,ENSG00000204472,ENSG00000089685,ENSG00000163041,ENSG00000044574,ENSG00000130741,ENSG00000116030,ENSG00000132274,ENSG00000166710,ENSG00000111229,ENSG00000147065,ENSG00000166974,ENSG00000166454,ENSG00000204899,ENSG00000166197,ENSG00000206127,ENSG00000138071,ENSG00000166598,ENSG00000156234,ENSG00000129675,ENSG00000129534,ENSG00000115155,ENSG00000093009,ENSG00000084623,ENSG00000158869,ENSG00000136717,ENSG00000100385,ENSG00000131504,ENSG00000180574,ENSG00000198821,ENSG00000067560,ENSG00000127952,ENSG00000114166,ENSG00000075340,ENSG00000133026,ENSG00000204256,ENSG00000151466,ENSG00000165283,ENSG00000173517,ENSG00000148175,ENSG00000132963,ENSG00000132182,ENSG00000158321,ENSG00000174371,ENSG00000160877,ENSG00000167286,ENSG00000042753,ENSG00000176101,ENSG00000070831,ENSG00000079691,ENSG00000170860,ENSG00000151239,ENSG00000197043,ENSG00000066279,ENSG00000075624,ENSG00000096968,ENSG00000165527,ENSG00000117155,ENSG00000127666,ENSG00000159111,ENSG00000223496,ENSG00000184897,ENSG00000055163,ENSG00000184640,ENSG00000127774,ENSG00000123338,ENSG00000109536,ENSG00000140450,ENSG00000171943,ENSG00000142867,ENSG00000109390,ENSG00000143740,ENSG00000198736,ENSG00000104738,ENSG00000119318,ENSG00000153044,ENSG00000137309,ENSG00000125354,ENSG00000189306,ENSG00000197409,ENSG00000137312,ENSG00000198851,ENSG00000232838,ENSG00000148218,ENSG00000242574,ENSG00000178685,ENSG00000147889,ENSG00000140575,ENSG00000111450,ENSG00000110218,ENSG00000127084,ENSG00000113387,ENSG00000111859 |
| GO:0002724 | regulation of T cell cytokine production | 0.0055758 | 32 | 712 | 7 | 0.0098315 | 0.2187500 | GO:BP | ENSG00000073861,ENSG00000134321,ENSG00000166710,ENSG00000204642,ENSG00000122122,ENSG00000028137,ENSG00000175104 |
| GO:0043066 | negative regulation of apoptotic process | 0.0060819 | 926 | 712 | 59 | 0.0828652 | 0.0637149 | GO:BP | ENSG00000004468,ENSG00000113721,ENSG00000126709,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000119917,ENSG00000164111,ENSG00000170315,ENSG00000105639,ENSG00000196924,ENSG00000118193,ENSG00000150093,ENSG00000172757,ENSG00000138795,ENSG00000232810,ENSG00000183691,ENSG00000204397,ENSG00000108179,ENSG00000134352,ENSG00000116288,ENSG00000249437,ENSG00000175793,ENSG00000156463,ENSG00000071205,ENSG00000170312,ENSG00000164830,ENSG00000141576,ENSG00000070018,ENSG00000055332,ENSG00000169230,ENSG00000065135,ENSG00000119335,ENSG00000148400,ENSG00000204472,ENSG00000089685,ENSG00000044574,ENSG00000163545,ENSG00000166598,ENSG00000118971,ENSG00000074800,ENSG00000105220,ENSG00000158869,ENSG00000158006,ENSG00000100385,ENSG00000067560,ENSG00000185507,ENSG00000103495,ENSG00000104765,ENSG00000172936,ENSG00000178719,ENSG00000096968,ENSG00000168329,ENSG00000123338,ENSG00000142867,ENSG00000126432,ENSG00000196839,ENSG00000137193,ENSG00000175104 |
| GO:0071103 | DNA conformation change | 0.0060819 | 323 | 712 | 27 | 0.0379213 | 0.0835913 | GO:BP | ENSG00000184357,ENSG00000155657,ENSG00000123485,ENSG00000170315,ENSG00000124575,ENSG00000105011,ENSG00000051341,ENSG00000188312,ENSG00000170312,ENSG00000119335,ENSG00000163041,ENSG00000129534,ENSG00000113810,ENSG00000204256,ENSG00000131747,ENSG00000136824,ENSG00000109805,ENSG00000184897,ENSG00000049541,ENSG00000104738,ENSG00000119318,ENSG00000153044,ENSG00000137309,ENSG00000197409,ENSG00000178685,ENSG00000147889,ENSG00000113387 |
| GO:0002905 | regulation of mature B cell apoptotic process | 0.0061065 | 4 | 712 | 3 | 0.0042135 | 0.7500000 | GO:BP | ENSG00000019582,ENSG00000142867,ENSG00000196839 |
| GO:0002906 | negative regulation of mature B cell apoptotic process | 0.0061065 | 4 | 712 | 3 | 0.0042135 | 0.7500000 | GO:BP | ENSG00000019582,ENSG00000142867,ENSG00000196839 |
| GO:0002901 | mature B cell apoptotic process | 0.0061065 | 4 | 712 | 3 | 0.0042135 | 0.7500000 | GO:BP | ENSG00000019582,ENSG00000142867,ENSG00000196839 |
| GO:0021943 | formation of radial glial scaffolds | 0.0061065 | 4 | 712 | 3 | 0.0042135 | 0.7500000 | GO:BP | ENSG00000196924,ENSG00000150093,ENSG00000138795 |
| GO:0006887 | exocytosis | 0.0061065 | 907 | 712 | 58 | 0.0814607 | 0.0639471 | GO:BP | ENSG00000172057,ENSG00000072110,ENSG00000108679,ENSG00000100321,ENSG00000155657,ENSG00000160014,ENSG00000164111,ENSG00000196924,ENSG00000117984,ENSG00000167461,ENSG00000111537,ENSG00000103769,ENSG00000005844,ENSG00000196230,ENSG00000134765,ENSG00000137563,ENSG00000187446,ENSG00000130402,ENSG00000213281,ENSG00000123131,ENSG00000148400,ENSG00000041353,ENSG00000064666,ENSG00000072958,ENSG00000166710,ENSG00000163823,ENSG00000138071,ENSG00000131236,ENSG00000021355,ENSG00000115155,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000100299,ENSG00000163131,ENSG00000131504,ENSG00000067560,ENSG00000172794,ENSG00000133026,ENSG00000204642,ENSG00000168961,ENSG00000148175,ENSG00000153310,ENSG00000171302,ENSG00000147234,ENSG00000139370,ENSG00000123338,ENSG00000143740,ENSG00000140284,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000140319,ENSG00000127951,ENSG00000148218,ENSG00000028137,ENSG00000140575,ENSG00000111450 |
| GO:0003332 | negative regulation of extracellular matrix constituent secretion | 0.0061065 | 4 | 712 | 3 | 0.0042135 | 0.7500000 | GO:BP | ENSG00000148400,ENSG00000111863,ENSG00000028137 |
| GO:0002286 | T cell activation involved in immune response | 0.0061065 | 104 | 712 | 13 | 0.0182584 | 0.1250000 | GO:BP | ENSG00000073861,ENSG00000135077,ENSG00000105639,ENSG00000137265,ENSG00000136167,ENSG00000096996,ENSG00000138795,ENSG00000111537,ENSG00000005844,ENSG00000158869,ENSG00000168961,ENSG00000127951,ENSG00000242574 |
| GO:0071840 | cellular component organization or biogenesis | 0.0062177 | 6667 | 712 | 310 | 0.4353933 | 0.0464977 | GO:BP | ENSG00000172057,ENSG00000100453,ENSG00000004468,ENSG00000196169,ENSG00000148773,ENSG00000119922,ENSG00000204267,ENSG00000113721,ENSG00000196126,ENSG00000183688,ENSG00000007402,ENSG00000229474,ENSG00000248905,ENSG00000072110,ENSG00000129595,ENSG00000156886,ENSG00000117724,ENSG00000157423,ENSG00000100321,ENSG00000179218,ENSG00000126709,ENSG00000184357,ENSG00000147459,ENSG00000154451,ENSG00000100427,ENSG00000080573,ENSG00000155657,ENSG00000163840,ENSG00000123485,ENSG00000231925,ENSG00000019582,ENSG00000117560,ENSG00000198513,ENSG00000159216,ENSG00000160014,ENSG00000034510,ENSG00000173482,ENSG00000130164,ENSG00000069702,ENSG00000091129,ENSG00000221866,ENSG00000101057,ENSG00000163029,ENSG00000170315,ENSG00000166503,ENSG00000156970,ENSG00000171848,ENSG00000125868,ENSG00000125864,ENSG00000117632,ENSG00000169252,ENSG00000160654,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000118193,ENSG00000112029,ENSG00000157216,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000105409,ENSG00000173848,ENSG00000138160,ENSG00000165617,ENSG00000125249,ENSG00000173114,ENSG00000172757,ENSG00000138795,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000112139,ENSG00000232810,ENSG00000183691,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000126787,ENSG00000176293,ENSG00000100749,ENSG00000108179,ENSG00000111640,ENSG00000139626,ENSG00000132646,ENSG00000103769,ENSG00000100380,ENSG00000108518,ENSG00000183741,ENSG00000005844,ENSG00000103148,ENSG00000137474,ENSG00000116288,ENSG00000196230,ENSG00000180644,ENSG00000073008,ENSG00000175793,ENSG00000169855,ENSG00000103966,ENSG00000124575,ENSG00000100918,ENSG00000105011,ENSG00000051341,ENSG00000131018,ENSG00000205413,ENSG00000187446,ENSG00000130402,ENSG00000188312,ENSG00000011426,ENSG00000071205,ENSG00000170312,ENSG00000105887,ENSG00000155846,ENSG00000136436,ENSG00000163359,ENSG00000185651,ENSG00000141576,ENSG00000117394,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000061337,ENSG00000215305,ENSG00000055332,ENSG00000242372,ENSG00000169230,ENSG00000153094,ENSG00000123416,ENSG00000152229,ENSG00000065135,ENSG00000213445,ENSG00000163520,ENSG00000123131,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000163041,ENSG00000044574,ENSG00000124587,ENSG00000171246,ENSG00000130741,ENSG00000116030,ENSG00000118263,ENSG00000064666,ENSG00000072958,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000111229,ENSG00000073803,ENSG00000163545,ENSG00000147065,ENSG00000166974,ENSG00000166454,ENSG00000204899,ENSG00000128578,ENSG00000166197,ENSG00000204822,ENSG00000126016,ENSG00000206127,ENSG00000253626,ENSG00000073910,ENSG00000138071,ENSG00000166598,ENSG00000129007,ENSG00000131236,ENSG00000111348,ENSG00000156234,ENSG00000129675,ENSG00000112031,ENSG00000129534,ENSG00000115155,ENSG00000093009,ENSG00000125871,ENSG00000074800,ENSG00000084623,ENSG00000122952,ENSG00000143228,ENSG00000158869,ENSG00000136717,ENSG00000163131,ENSG00000100385,ENSG00000131504,ENSG00000180574,ENSG00000198821,ENSG00000011485,ENSG00000067560,ENSG00000132932,ENSG00000127952,ENSG00000114166,ENSG00000075340,ENSG00000133026,ENSG00000113810,ENSG00000149294,ENSG00000204256,ENSG00000006625,ENSG00000151466,ENSG00000158882,ENSG00000172270,ENSG00000122877,ENSG00000165283,ENSG00000173517,ENSG00000172795,ENSG00000148175,ENSG00000131747,ENSG00000171617,ENSG00000141736,ENSG00000132963,ENSG00000132182,ENSG00000158321,ENSG00000174371,ENSG00000160877,ENSG00000167286,ENSG00000189369,ENSG00000139579,ENSG00000162676,ENSG00000111863,ENSG00000106462,ENSG00000042753,ENSG00000178996,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000152253,ENSG00000079691,ENSG00000112996,ENSG00000124920,ENSG00000170860,ENSG00000171169,ENSG00000151239,ENSG00000101079,ENSG00000166035,ENSG00000141030,ENSG00000074071,ENSG00000197043,ENSG00000132670,ENSG00000066279,ENSG00000075624,ENSG00000096968,ENSG00000136824,ENSG00000165527,ENSG00000117155,ENSG00000105612,ENSG00000168329,ENSG00000127666,ENSG00000159111,ENSG00000109084,ENSG00000105697,ENSG00000223496,ENSG00000197956,ENSG00000109805,ENSG00000121579,ENSG00000196072,ENSG00000184897,ENSG00000116670,ENSG00000055163,ENSG00000184640,ENSG00000132386,ENSG00000127774,ENSG00000123338,ENSG00000010270,ENSG00000109536,ENSG00000140450,ENSG00000171943,ENSG00000124688,ENSG00000142867,ENSG00000114126,ENSG00000109390,ENSG00000143740,ENSG00000198736,ENSG00000049541,ENSG00000104738,ENSG00000119318,ENSG00000172531,ENSG00000178691,ENSG00000129968,ENSG00000153044,ENSG00000140284,ENSG00000137309,ENSG00000125354,ENSG00000254087,ENSG00000160255,ENSG00000189306,ENSG00000104472,ENSG00000182628,ENSG00000164576,ENSG00000197409,ENSG00000137312,ENSG00000198851,ENSG00000232838,ENSG00000148218,ENSG00000242574,ENSG00000134690,ENSG00000154518,ENSG00000028137,ENSG00000178685,ENSG00000169223,ENSG00000147889,ENSG00000139926,ENSG00000140575,ENSG00000111450,ENSG00000110218,ENSG00000169554,ENSG00000127084,ENSG00000120280,ENSG00000113387,ENSG00000111859 |
| GO:1900024 | regulation of substrate adhesion-dependent cell spreading | 0.0062753 | 54 | 712 | 9 | 0.0126404 | 0.1666667 | GO:BP | ENSG00000179218,ENSG00000147459,ENSG00000196924,ENSG00000179051,ENSG00000117228,ENSG00000130402,ENSG00000070831,ENSG00000079691,ENSG00000111859 |
| GO:0065008 | regulation of biological quality | 0.0062753 | 4156 | 712 | 205 | 0.2879213 | 0.0493263 | GO:BP | ENSG00000172057,ENSG00000100453,ENSG00000004468,ENSG00000164308,ENSG00000113721,ENSG00000196126,ENSG00000007402,ENSG00000092010,ENSG00000248905,ENSG00000125347,ENSG00000100321,ENSG00000179218,ENSG00000126709,ENSG00000184357,ENSG00000092068,ENSG00000147459,ENSG00000163421,ENSG00000231925,ENSG00000019582,ENSG00000142669,ENSG00000117560,ENSG00000160014,ENSG00000034510,ENSG00000173482,ENSG00000130164,ENSG00000115415,ENSG00000143870,ENSG00000186469,ENSG00000069702,ENSG00000091129,ENSG00000100911,ENSG00000221866,ENSG00000164111,ENSG00000163029,ENSG00000170315,ENSG00000125868,ENSG00000105639,ENSG00000117632,ENSG00000169252,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000169442,ENSG00000121039,ENSG00000167461,ENSG00000105409,ENSG00000165617,ENSG00000172331,ENSG00000173114,ENSG00000172757,ENSG00000110090,ENSG00000111537,ENSG00000112139,ENSG00000099194,ENSG00000232810,ENSG00000134308,ENSG00000108179,ENSG00000111640,ENSG00000118777,ENSG00000132646,ENSG00000103769,ENSG00000108518,ENSG00000116288,ENSG00000196230,ENSG00000175793,ENSG00000023572,ENSG00000204264,ENSG00000131018,ENSG00000188191,ENSG00000187446,ENSG00000105887,ENSG00000155846,ENSG00000117394,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000061337,ENSG00000169230,ENSG00000153094,ENSG00000104687,ENSG00000123131,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000164211,ENSG00000089127,ENSG00000152256,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000121297,ENSG00000163041,ENSG00000044574,ENSG00000124587,ENSG00000130741,ENSG00000116030,ENSG00000118263,ENSG00000173786,ENSG00000166710,ENSG00000111229,ENSG00000073803,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000128578,ENSG00000138071,ENSG00000166598,ENSG00000148730,ENSG00000156234,ENSG00000115155,ENSG00000185650,ENSG00000100605,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000196449,ENSG00000136717,ENSG00000158006,ENSG00000170881,ENSG00000125148,ENSG00000139921,ENSG00000131504,ENSG00000128039,ENSG00000180574,ENSG00000067560,ENSG00000132932,ENSG00000125944,ENSG00000183172,ENSG00000213719,ENSG00000075340,ENSG00000133026,ENSG00000168961,ENSG00000122122,ENSG00000122877,ENSG00000165283,ENSG00000172795,ENSG00000174371,ENSG00000118564,ENSG00000187608,ENSG00000198843,ENSG00000139579,ENSG00000162676,ENSG00000111863,ENSG00000106462,ENSG00000104765,ENSG00000070831,ENSG00000079691,ENSG00000172936,ENSG00000171169,ENSG00000151239,ENSG00000178719,ENSG00000166035,ENSG00000197043,ENSG00000066279,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000130348,ENSG00000079999,ENSG00000170837,ENSG00000165527,ENSG00000105612,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000109084,ENSG00000105697,ENSG00000223496,ENSG00000196072,ENSG00000102931,ENSG00000125648,ENSG00000184154,ENSG00000132386,ENSG00000049239,ENSG00000123338,ENSG00000010270,ENSG00000128272,ENSG00000148337,ENSG00000142867,ENSG00000111335,ENSG00000114126,ENSG00000143740,ENSG00000126432,ENSG00000049541,ENSG00000196834,ENSG00000172531,ENSG00000129968,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000213366,ENSG00000155660,ENSG00000197409,ENSG00000137312,ENSG00000196839,ENSG00000177674,ENSG00000028137,ENSG00000147889,ENSG00000137193,ENSG00000111450,ENSG00000175104,ENSG00000127084,ENSG00000120280,ENSG00000166794,ENSG00000112759 |
| GO:0051056 | regulation of small GTPase mediated signal transduction | 0.0063510 | 342 | 712 | 28 | 0.0393258 | 0.0818713 | GO:BP | ENSG00000113721,ENSG00000198826,ENSG00000205336,ENSG00000117632,ENSG00000118193,ENSG00000150093,ENSG00000173848,ENSG00000111206,ENSG00000213390,ENSG00000169855,ENSG00000071205,ENSG00000213445,ENSG00000148400,ENSG00000166974,ENSG00000126016,ENSG00000111348,ENSG00000129675,ENSG00000168421,ENSG00000134909,ENSG00000067560,ENSG00000158321,ENSG00000070831,ENSG00000096968,ENSG00000165527,ENSG00000117155,ENSG00000254087,ENSG00000137312,ENSG00000127084 |
| GO:0097190 | apoptotic signaling pathway | 0.0063510 | 616 | 712 | 43 | 0.0603933 | 0.0698052 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000100450,ENSG00000126709,ENSG00000019582,ENSG00000117560,ENSG00000170315,ENSG00000167004,ENSG00000111537,ENSG00000232810,ENSG00000183691,ENSG00000134308,ENSG00000108179,ENSG00000116288,ENSG00000175793,ENSG00000165949,ENSG00000169230,ENSG00000153094,ENSG00000065135,ENSG00000152256,ENSG00000007968,ENSG00000110448,ENSG00000196954,ENSG00000074800,ENSG00000127952,ENSG00000189283,ENSG00000165304,ENSG00000006625,ENSG00000168961,ENSG00000103495,ENSG00000104765,ENSG00000178719,ENSG00000197043,ENSG00000096968,ENSG00000168329,ENSG00000127666,ENSG00000196072,ENSG00000128272,ENSG00000142867,ENSG00000114126,ENSG00000172531,ENSG00000198851,ENSG00000028137 |
| GO:0055094 | response to lipoprotein particle | 0.0064605 | 33 | 712 | 7 | 0.0098315 | 0.2121212 | GO:BP | ENSG00000130164,ENSG00000150093,ENSG00000158869,ENSG00000111863,ENSG00000172936,ENSG00000127666,ENSG00000160255 |
| GO:0044772 | mitotic cell cycle phase transition | 0.0064605 | 598 | 712 | 42 | 0.0589888 | 0.0702341 | GO:BP | ENSG00000092010,ENSG00000117724,ENSG00000165891,ENSG00000160014,ENSG00000100911,ENSG00000156970,ENSG00000171848,ENSG00000118193,ENSG00000112029,ENSG00000150093,ENSG00000165617,ENSG00000111206,ENSG00000179051,ENSG00000126787,ENSG00000176890,ENSG00000132646,ENSG00000103769,ENSG00000196230,ENSG00000175793,ENSG00000204264,ENSG00000011426,ENSG00000170312,ENSG00000092853,ENSG00000061337,ENSG00000204472,ENSG00000118971,ENSG00000093009,ENSG00000185650,ENSG00000143476,ENSG00000053254,ENSG00000165304,ENSG00000162676,ENSG00000106462,ENSG00000176101,ENSG00000116670,ENSG00000072571,ENSG00000124688,ENSG00000114126,ENSG00000104738,ENSG00000041357,ENSG00000136104,ENSG00000147889 |
| GO:0002428 | antigen processing and presentation of peptide antigen via MHC class Ib | 0.0064605 | 9 | 712 | 4 | 0.0056180 | 0.4444444 | GO:BP | ENSG00000204267,ENSG00000166710,ENSG00000204642,ENSG00000204592 |
| GO:0060700 | regulation of ribonuclease activity | 0.0064605 | 9 | 712 | 4 | 0.0056180 | 0.4444444 | GO:BP | ENSG00000135114,ENSG00000089127,ENSG00000111331,ENSG00000111335 |
| GO:0042089 | cytokine biosynthetic process | 0.0064605 | 133 | 712 | 15 | 0.0210674 | 0.1127820 | GO:BP | ENSG00000125347,ENSG00000089692,ENSG00000019582,ENSG00000137265,ENSG00000123609,ENSG00000111537,ENSG00000232810,ENSG00000185507,ENSG00000172936,ENSG00000096968,ENSG00000168329,ENSG00000127666,ENSG00000142867,ENSG00000198851,ENSG00000175104 |
| GO:0002275 | myeloid cell activation involved in immune response | 0.0065376 | 542 | 712 | 39 | 0.0547753 | 0.0719557 | GO:BP | ENSG00000172057,ENSG00000100321,ENSG00000135077,ENSG00000117984,ENSG00000005844,ENSG00000196230,ENSG00000134765,ENSG00000137563,ENSG00000213281,ENSG00000123131,ENSG00000064666,ENSG00000072958,ENSG00000166710,ENSG00000138071,ENSG00000131236,ENSG00000021355,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000100299,ENSG00000163131,ENSG00000131504,ENSG00000067560,ENSG00000172794,ENSG00000168961,ENSG00000148175,ENSG00000171302,ENSG00000147234,ENSG00000127666,ENSG00000139370,ENSG00000123338,ENSG00000140284,ENSG00000254087,ENSG00000160255,ENSG00000140319,ENSG00000127951,ENSG00000148218,ENSG00000028137,ENSG00000140575 |
| GO:0007015 | actin filament organization | 0.0065945 | 414 | 712 | 32 | 0.0449438 | 0.0772947 | GO:BP | ENSG00000183688,ENSG00000248905,ENSG00000072110,ENSG00000155657,ENSG00000034510,ENSG00000125868,ENSG00000117632,ENSG00000196924,ENSG00000136167,ENSG00000172757,ENSG00000108518,ENSG00000130402,ENSG00000105887,ENSG00000155846,ENSG00000204472,ENSG00000111229,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000136717,ENSG00000131504,ENSG00000067560,ENSG00000075340,ENSG00000070831,ENSG00000079691,ENSG00000151239,ENSG00000096968,ENSG00000165527,ENSG00000116670,ENSG00000123338,ENSG00000198736,ENSG00000111859 |
| GO:0015833 | peptide transport | 0.0067595 | 2161 | 712 | 117 | 0.1643258 | 0.0541416 | GO:BP | ENSG00000004468,ENSG00000204267,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000117724,ENSG00000100321,ENSG00000179218,ENSG00000135077,ENSG00000154451,ENSG00000100427,ENSG00000155657,ENSG00000163840,ENSG00000182054,ENSG00000231925,ENSG00000019582,ENSG00000151502,ENSG00000164111,ENSG00000170315,ENSG00000160654,ENSG00000196924,ENSG00000186470,ENSG00000136167,ENSG00000167461,ENSG00000110090,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000134308,ENSG00000204397,ENSG00000111640,ENSG00000103769,ENSG00000189319,ENSG00000137474,ENSG00000116288,ENSG00000134321,ENSG00000175793,ENSG00000143742,ENSG00000136274,ENSG00000187446,ENSG00000130402,ENSG00000170312,ENSG00000122223,ENSG00000185651,ENSG00000117394,ENSG00000171603,ENSG00000165949,ENSG00000185304,ENSG00000152969,ENSG00000215305,ENSG00000242372,ENSG00000148400,ENSG00000157601,ENSG00000041353,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000044574,ENSG00000124587,ENSG00000118263,ENSG00000072958,ENSG00000104805,ENSG00000185745,ENSG00000180667,ENSG00000166197,ENSG00000253626,ENSG00000166598,ENSG00000157985,ENSG00000132661,ENSG00000021355,ENSG00000172803,ENSG00000105220,ENSG00000213064,ENSG00000172794,ENSG00000133026,ENSG00000115267,ENSG00000168961,ENSG00000158882,ENSG00000122877,ENSG00000148175,ENSG00000141736,ENSG00000204592,ENSG00000132182,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000111863,ENSG00000042753,ENSG00000178996,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000096968,ENSG00000170837,ENSG00000165527,ENSG00000117155,ENSG00000162385,ENSG00000139370,ENSG00000127022,ENSG00000102931,ENSG00000140450,ENSG00000120709,ENSG00000143740,ENSG00000140284,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000140319,ENSG00000155660,ENSG00000172667,ENSG00000184575,ENSG00000028137,ENSG00000169223,ENSG00000111481,ENSG00000111450,ENSG00000175104,ENSG00000110218 |
| GO:0042107 | cytokine metabolic process | 0.0068861 | 134 | 712 | 15 | 0.0210674 | 0.1119403 | GO:BP | ENSG00000125347,ENSG00000089692,ENSG00000019582,ENSG00000137265,ENSG00000123609,ENSG00000111537,ENSG00000232810,ENSG00000185507,ENSG00000172936,ENSG00000096968,ENSG00000168329,ENSG00000127666,ENSG00000142867,ENSG00000198851,ENSG00000175104 |
| GO:0042127 | regulation of cell population proliferation | 0.0069615 | 1749 | 712 | 98 | 0.1376404 | 0.0560320 | GO:BP | ENSG00000004468,ENSG00000113721,ENSG00000196126,ENSG00000163599,ENSG00000125347,ENSG00000179218,ENSG00000175274,ENSG00000135077,ENSG00000165891,ENSG00000182054,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000144354,ENSG00000164649,ENSG00000173482,ENSG00000115415,ENSG00000119917,ENSG00000069702,ENSG00000205336,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000196924,ENSG00000146674,ENSG00000118193,ENSG00000112029,ENSG00000120057,ENSG00000157216,ENSG00000150093,ENSG00000096996,ENSG00000111206,ENSG00000133321,ENSG00000138795,ENSG00000111537,ENSG00000102554,ENSG00000232810,ENSG00000183691,ENSG00000183734,ENSG00000134352,ENSG00000175793,ENSG00000169855,ENSG00000170312,ENSG00000185885,ENSG00000070018,ENSG00000055332,ENSG00000065135,ENSG00000213281,ENSG00000123131,ENSG00000148400,ENSG00000204472,ENSG00000089685,ENSG00000064666,ENSG00000166710,ENSG00000166197,ENSG00000118971,ENSG00000185650,ENSG00000071994,ENSG00000013725,ENSG00000170881,ENSG00000184916,ENSG00000067560,ENSG00000132932,ENSG00000114166,ENSG00000168961,ENSG00000122122,ENSG00000141736,ENSG00000204592,ENSG00000160877,ENSG00000213626,ENSG00000157873,ENSG00000103495,ENSG00000106462,ENSG00000070831,ENSG00000172936,ENSG00000066279,ENSG00000096968,ENSG00000168329,ENSG00000127666,ENSG00000197956,ENSG00000132386,ENSG00000123338,ENSG00000178691,ENSG00000137309,ENSG00000254087,ENSG00000177076,ENSG00000198851,ENSG00000196839,ENSG00000136104,ENSG00000155090,ENSG00000242574,ENSG00000028137,ENSG00000178685,ENSG00000147889,ENSG00000137193,ENSG00000175104,ENSG00000078124,ENSG00000081985 |
| GO:0050868 | negative regulation of T cell activation | 0.0070340 | 120 | 712 | 14 | 0.0196629 | 0.1166667 | GO:BP | ENSG00000196126,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000105639,ENSG00000168961,ENSG00000141736,ENSG00000157873,ENSG00000127951,ENSG00000147889 |
| GO:0045073 | regulation of chemokine biosynthetic process | 0.0070443 | 16 | 712 | 5 | 0.0070225 | 0.3125000 | GO:BP | ENSG00000019582,ENSG00000111537,ENSG00000232810,ENSG00000172936,ENSG00000127666 |
| GO:0001912 | positive regulation of leukocyte mediated cytotoxicity | 0.0070720 | 44 | 712 | 8 | 0.0112360 | 0.1818182 | GO:BP | ENSG00000117281,ENSG00000089692,ENSG00000096996,ENSG00000073008,ENSG00000166710,ENSG00000204642,ENSG00000204592,ENSG00000153310 |
| GO:0007059 | chromosome segregation | 0.0071220 | 328 | 712 | 27 | 0.0379213 | 0.0823171 | GO:BP | ENSG00000148773,ENSG00000117724,ENSG00000155657,ENSG00000123485,ENSG00000163029,ENSG00000156970,ENSG00000118193,ENSG00000112029,ENSG00000179051,ENSG00000126787,ENSG00000103769,ENSG00000100918,ENSG00000089685,ENSG00000138071,ENSG00000122952,ENSG00000143228,ENSG00000113810,ENSG00000131747,ENSG00000070831,ENSG00000152253,ENSG00000136824,ENSG00000109805,ENSG00000121579,ENSG00000116670,ENSG00000153044,ENSG00000182628,ENSG00000134690 |
| GO:0046903 | secretion | 0.0072856 | 1709 | 712 | 96 | 0.1348315 | 0.0561732 | GO:BP | ENSG00000172057,ENSG00000004468,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000072110,ENSG00000108679,ENSG00000100321,ENSG00000135077,ENSG00000154451,ENSG00000155657,ENSG00000182054,ENSG00000019582,ENSG00000160014,ENSG00000164111,ENSG00000196924,ENSG00000117984,ENSG00000186470,ENSG00000167461,ENSG00000110090,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000204397,ENSG00000111640,ENSG00000103769,ENSG00000005844,ENSG00000116288,ENSG00000196230,ENSG00000134765,ENSG00000134321,ENSG00000137563,ENSG00000187446,ENSG00000130402,ENSG00000122223,ENSG00000117394,ENSG00000213281,ENSG00000123131,ENSG00000148400,ENSG00000041353,ENSG00000204472,ENSG00000089685,ENSG00000118263,ENSG00000064666,ENSG00000072958,ENSG00000166710,ENSG00000163823,ENSG00000138071,ENSG00000131236,ENSG00000021355,ENSG00000115155,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000100299,ENSG00000163131,ENSG00000131504,ENSG00000067560,ENSG00000172794,ENSG00000133026,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000148175,ENSG00000204592,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000111863,ENSG00000153310,ENSG00000171302,ENSG00000147234,ENSG00000096968,ENSG00000170837,ENSG00000165527,ENSG00000139370,ENSG00000127022,ENSG00000102931,ENSG00000123338,ENSG00000111335,ENSG00000143740,ENSG00000140284,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000140319,ENSG00000127951,ENSG00000155660,ENSG00000196839,ENSG00000148218,ENSG00000028137,ENSG00000140575,ENSG00000111450,ENSG00000175104,ENSG00000110218,ENSG00000112759 |
| GO:0046718 | viral entry into host cell | 0.0075394 | 121 | 712 | 14 | 0.0196629 | 0.1157025 | GO:BP | ENSG00000196126,ENSG00000019582,ENSG00000130164,ENSG00000142089,ENSG00000150093,ENSG00000139626,ENSG00000185201,ENSG00000073008,ENSG00000170312,ENSG00000185885,ENSG00000149294,ENSG00000168961,ENSG00000157873,ENSG00000132256 |
| GO:0071887 | leukocyte apoptotic process | 0.0075394 | 107 | 712 | 13 | 0.0182584 | 0.1214953 | GO:BP | ENSG00000019582,ENSG00000117560,ENSG00000105639,ENSG00000160654,ENSG00000169230,ENSG00000153094,ENSG00000158869,ENSG00000185507,ENSG00000168961,ENSG00000142867,ENSG00000254087,ENSG00000196839,ENSG00000147889 |
| GO:0044770 | cell cycle phase transition | 0.0075613 | 642 | 712 | 44 | 0.0617978 | 0.0685358 | GO:BP | ENSG00000092010,ENSG00000117724,ENSG00000165891,ENSG00000160014,ENSG00000100911,ENSG00000156970,ENSG00000171848,ENSG00000118193,ENSG00000112029,ENSG00000150093,ENSG00000165617,ENSG00000111206,ENSG00000179051,ENSG00000126787,ENSG00000176890,ENSG00000132646,ENSG00000103769,ENSG00000196230,ENSG00000111602,ENSG00000175793,ENSG00000204264,ENSG00000011426,ENSG00000170312,ENSG00000185651,ENSG00000092853,ENSG00000061337,ENSG00000204472,ENSG00000118971,ENSG00000093009,ENSG00000185650,ENSG00000143476,ENSG00000053254,ENSG00000165304,ENSG00000162676,ENSG00000106462,ENSG00000176101,ENSG00000116670,ENSG00000072571,ENSG00000124688,ENSG00000114126,ENSG00000104738,ENSG00000041357,ENSG00000136104,ENSG00000147889 |
| GO:0002758 | innate immune response-activating signal transduction | 0.0078857 | 296 | 712 | 25 | 0.0351124 | 0.0844595 | GO:BP | ENSG00000092010,ENSG00000125347,ENSG00000135077,ENSG00000155629,ENSG00000100911,ENSG00000170315,ENSG00000137265,ENSG00000134321,ENSG00000204264,ENSG00000213281,ENSG00000166598,ENSG00000158869,ENSG00000163131,ENSG00000185507,ENSG00000115267,ENSG00000162676,ENSG00000172936,ENSG00000164164,ENSG00000127666,ENSG00000142867,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000137312,ENSG00000175104 |
| GO:0030029 | actin filament-based process | 0.0081783 | 781 | 712 | 51 | 0.0716292 | 0.0653009 | GO:BP | ENSG00000113721,ENSG00000183688,ENSG00000248905,ENSG00000072110,ENSG00000129595,ENSG00000179218,ENSG00000155657,ENSG00000034510,ENSG00000125868,ENSG00000117632,ENSG00000196924,ENSG00000150093,ENSG00000136167,ENSG00000125249,ENSG00000172757,ENSG00000232810,ENSG00000108518,ENSG00000137474,ENSG00000130402,ENSG00000011426,ENSG00000105887,ENSG00000155846,ENSG00000204472,ENSG00000116030,ENSG00000064666,ENSG00000111229,ENSG00000163545,ENSG00000126016,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000111348,ENSG00000136717,ENSG00000131504,ENSG00000067560,ENSG00000075340,ENSG00000133026,ENSG00000158321,ENSG00000070831,ENSG00000079691,ENSG00000151239,ENSG00000075624,ENSG00000096968,ENSG00000165527,ENSG00000116670,ENSG00000123338,ENSG00000198736,ENSG00000092841,ENSG00000139926,ENSG00000127084,ENSG00000111859 |
| GO:0042886 | amide transport | 0.0081811 | 2196 | 712 | 118 | 0.1657303 | 0.0537341 | GO:BP | ENSG00000004468,ENSG00000204267,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000117724,ENSG00000100321,ENSG00000179218,ENSG00000135077,ENSG00000154451,ENSG00000100427,ENSG00000155657,ENSG00000163840,ENSG00000182054,ENSG00000231925,ENSG00000019582,ENSG00000151502,ENSG00000164111,ENSG00000170315,ENSG00000160654,ENSG00000196924,ENSG00000186470,ENSG00000136167,ENSG00000167461,ENSG00000110090,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000134308,ENSG00000204397,ENSG00000111640,ENSG00000118777,ENSG00000103769,ENSG00000189319,ENSG00000137474,ENSG00000116288,ENSG00000134321,ENSG00000175793,ENSG00000143742,ENSG00000136274,ENSG00000187446,ENSG00000130402,ENSG00000170312,ENSG00000122223,ENSG00000185651,ENSG00000117394,ENSG00000171603,ENSG00000165949,ENSG00000185304,ENSG00000152969,ENSG00000215305,ENSG00000242372,ENSG00000148400,ENSG00000157601,ENSG00000041353,ENSG00000204472,ENSG00000171130,ENSG00000089685,ENSG00000044574,ENSG00000124587,ENSG00000118263,ENSG00000072958,ENSG00000104805,ENSG00000185745,ENSG00000180667,ENSG00000166197,ENSG00000253626,ENSG00000166598,ENSG00000157985,ENSG00000132661,ENSG00000021355,ENSG00000172803,ENSG00000105220,ENSG00000213064,ENSG00000172794,ENSG00000133026,ENSG00000115267,ENSG00000168961,ENSG00000158882,ENSG00000122877,ENSG00000148175,ENSG00000141736,ENSG00000204592,ENSG00000132182,ENSG00000187608,ENSG00000157873,ENSG00000198843,ENSG00000111863,ENSG00000042753,ENSG00000178996,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000096968,ENSG00000170837,ENSG00000165527,ENSG00000117155,ENSG00000162385,ENSG00000139370,ENSG00000127022,ENSG00000102931,ENSG00000140450,ENSG00000120709,ENSG00000143740,ENSG00000140284,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000140319,ENSG00000155660,ENSG00000172667,ENSG00000184575,ENSG00000028137,ENSG00000169223,ENSG00000111481,ENSG00000111450,ENSG00000175104,ENSG00000110218 |
| GO:0007265 | Ras protein signal transduction | 0.0082576 | 457 | 712 | 34 | 0.0477528 | 0.0743982 | GO:BP | ENSG00000113721,ENSG00000205336,ENSG00000117632,ENSG00000118193,ENSG00000150093,ENSG00000167461,ENSG00000173848,ENSG00000125249,ENSG00000111206,ENSG00000172757,ENSG00000103769,ENSG00000116288,ENSG00000169855,ENSG00000213281,ENSG00000148400,ENSG00000041353,ENSG00000204472,ENSG00000166974,ENSG00000111348,ENSG00000129675,ENSG00000181467,ENSG00000168421,ENSG00000067560,ENSG00000172794,ENSG00000158321,ENSG00000070831,ENSG00000096968,ENSG00000165527,ENSG00000117155,ENSG00000254087,ENSG00000139998,ENSG00000137312,ENSG00000147889,ENSG00000127084 |
| GO:0009636 | response to toxic substance | 0.0082576 | 550 | 712 | 39 | 0.0547753 | 0.0709091 | GO:BP | ENSG00000113721,ENSG00000092068,ENSG00000134184,ENSG00000160014,ENSG00000115415,ENSG00000173848,ENSG00000232810,ENSG00000176890,ENSG00000108179,ENSG00000118777,ENSG00000132646,ENSG00000116288,ENSG00000111602,ENSG00000023572,ENSG00000137563,ENSG00000170312,ENSG00000104687,ENSG00000123131,ENSG00000173786,ENSG00000166710,ENSG00000104805,ENSG00000138071,ENSG00000100299,ENSG00000125148,ENSG00000011485,ENSG00000067560,ENSG00000134202,ENSG00000198843,ENSG00000106462,ENSG00000075624,ENSG00000105697,ENSG00000148908,ENSG00000128272,ENSG00000126432,ENSG00000254087,ENSG00000213366,ENSG00000196839,ENSG00000148218,ENSG00000137193 |
| GO:0002221 | pattern recognition receptor signaling pathway | 0.0082576 | 198 | 712 | 19 | 0.0266854 | 0.0959596 | GO:BP | ENSG00000125347,ENSG00000135077,ENSG00000155629,ENSG00000170315,ENSG00000137265,ENSG00000134321,ENSG00000166598,ENSG00000163131,ENSG00000185507,ENSG00000115267,ENSG00000162676,ENSG00000172936,ENSG00000164164,ENSG00000127666,ENSG00000142867,ENSG00000254087,ENSG00000160255,ENSG00000137312,ENSG00000175104 |
| GO:1903038 | negative regulation of leukocyte cell-cell adhesion | 0.0083254 | 137 | 712 | 15 | 0.0210674 | 0.1094891 | GO:BP | ENSG00000196126,ENSG00000073861,ENSG00000163599,ENSG00000125347,ENSG00000135077,ENSG00000089692,ENSG00000019582,ENSG00000159216,ENSG00000105639,ENSG00000168961,ENSG00000141736,ENSG00000157873,ENSG00000111863,ENSG00000127951,ENSG00000147889 |
| GO:0051092 | positive regulation of NF-kappaB transcription factor activity | 0.0083729 | 152 | 712 | 16 | 0.0224719 | 0.1052632 | GO:BP | ENSG00000170315,ENSG00000232810,ENSG00000204397,ENSG00000105887,ENSG00000055332,ENSG00000132274,ENSG00000073803,ENSG00000168961,ENSG00000172936,ENSG00000168329,ENSG00000127666,ENSG00000142867,ENSG00000160255,ENSG00000137312,ENSG00000132256,ENSG00000175104 |
| GO:0010243 | response to organonitrogen compound | 0.0083729 | 1085 | 712 | 66 | 0.0926966 | 0.0608295 | GO:BP | ENSG00000160014,ENSG00000130164,ENSG00000115415,ENSG00000186469,ENSG00000069702,ENSG00000164111,ENSG00000105639,ENSG00000169252,ENSG00000196924,ENSG00000150093,ENSG00000167461,ENSG00000105409,ENSG00000172757,ENSG00000102554,ENSG00000232810,ENSG00000176890,ENSG00000132646,ENSG00000111602,ENSG00000137563,ENSG00000188191,ENSG00000170312,ENSG00000155846,ENSG00000117394,ENSG00000070018,ENSG00000242372,ENSG00000153094,ENSG00000065135,ENSG00000148400,ENSG00000204472,ENSG00000171130,ENSG00000044574,ENSG00000180667,ENSG00000138071,ENSG00000166598,ENSG00000148730,ENSG00000196954,ENSG00000185650,ENSG00000105220,ENSG00000158869,ENSG00000170881,ENSG00000131504,ENSG00000011485,ENSG00000067560,ENSG00000114166,ENSG00000172270,ENSG00000122877,ENSG00000103994,ENSG00000111863,ENSG00000106462,ENSG00000172936,ENSG00000132670,ENSG00000075624,ENSG00000096968,ENSG00000162104,ENSG00000127666,ENSG00000148908,ENSG00000128272,ENSG00000254087,ENSG00000160255,ENSG00000213366,ENSG00000196839,ENSG00000155090,ENSG00000148218,ENSG00000177674,ENSG00000140575,ENSG00000110218 |
| GO:0043299 | leukocyte degranulation | 0.0083928 | 532 | 712 | 38 | 0.0533708 | 0.0714286 | GO:BP | ENSG00000172057,ENSG00000100321,ENSG00000117984,ENSG00000005844,ENSG00000196230,ENSG00000134765,ENSG00000137563,ENSG00000213281,ENSG00000123131,ENSG00000064666,ENSG00000072958,ENSG00000166710,ENSG00000138071,ENSG00000131236,ENSG00000021355,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000100299,ENSG00000163131,ENSG00000131504,ENSG00000067560,ENSG00000172794,ENSG00000204642,ENSG00000168961,ENSG00000148175,ENSG00000171302,ENSG00000147234,ENSG00000139370,ENSG00000123338,ENSG00000140284,ENSG00000254087,ENSG00000160255,ENSG00000140319,ENSG00000127951,ENSG00000148218,ENSG00000028137,ENSG00000140575 |
| GO:0010950 | positive regulation of endopeptidase activity | 0.0084901 | 183 | 712 | 18 | 0.0252809 | 0.0983607 | GO:BP | ENSG00000092010,ENSG00000117560,ENSG00000100911,ENSG00000117984,ENSG00000232810,ENSG00000169855,ENSG00000169230,ENSG00000153094,ENSG00000196954,ENSG00000071994,ENSG00000067560,ENSG00000168961,ENSG00000096968,ENSG00000055163,ENSG00000142867,ENSG00000254087,ENSG00000177076,ENSG00000147889 |
| GO:0042035 | regulation of cytokine biosynthetic process | 0.0085602 | 123 | 712 | 14 | 0.0196629 | 0.1138211 | GO:BP | ENSG00000125347,ENSG00000089692,ENSG00000019582,ENSG00000137265,ENSG00000123609,ENSG00000111537,ENSG00000232810,ENSG00000172936,ENSG00000096968,ENSG00000168329,ENSG00000127666,ENSG00000142867,ENSG00000198851,ENSG00000175104 |
| GO:0032663 | regulation of interleukin-2 production | 0.0085787 | 57 | 712 | 9 | 0.0126404 | 0.1578947 | GO:BP | ENSG00000073861,ENSG00000135077,ENSG00000089692,ENSG00000159216,ENSG00000137265,ENSG00000117228,ENSG00000122122,ENSG00000198851,ENSG00000175104 |
| GO:0071402 | cellular response to lipoprotein particle stimulus | 0.0086344 | 35 | 712 | 7 | 0.0098315 | 0.2000000 | GO:BP | ENSG00000130164,ENSG00000150093,ENSG00000158869,ENSG00000111863,ENSG00000172936,ENSG00000127666,ENSG00000160255 |
| GO:0051444 | negative regulation of ubiquitin-protein transferase activity | 0.0089566 | 17 | 712 | 5 | 0.0070225 | 0.2941176 | GO:BP | ENSG00000163840,ENSG00000112029,ENSG00000116288,ENSG00000116670,ENSG00000147889 |
| GO:0008154 | actin polymerization or depolymerization | 0.0089566 | 216 | 712 | 20 | 0.0280899 | 0.0925926 | GO:BP | ENSG00000248905,ENSG00000034510,ENSG00000125868,ENSG00000172757,ENSG00000108518,ENSG00000105887,ENSG00000204472,ENSG00000111229,ENSG00000138071,ENSG00000131236,ENSG00000136717,ENSG00000131504,ENSG00000067560,ENSG00000075340,ENSG00000079691,ENSG00000151239,ENSG00000096968,ENSG00000165527,ENSG00000123338,ENSG00000198736 |
| GO:0042033 | chemokine biosynthetic process | 0.0089566 | 17 | 712 | 5 | 0.0070225 | 0.2941176 | GO:BP | ENSG00000019582,ENSG00000111537,ENSG00000232810,ENSG00000172936,ENSG00000127666 |
| GO:0050755 | chemokine metabolic process | 0.0089566 | 17 | 712 | 5 | 0.0070225 | 0.2941176 | GO:BP | ENSG00000019582,ENSG00000111537,ENSG00000232810,ENSG00000172936,ENSG00000127666 |
| GO:0051050 | positive regulation of transport | 0.0091914 | 1008 | 712 | 62 | 0.0870787 | 0.0615079 | GO:BP | ENSG00000100453,ENSG00000004468,ENSG00000113721,ENSG00000117281,ENSG00000196126,ENSG00000179218,ENSG00000135077,ENSG00000100427,ENSG00000155657,ENSG00000160014,ENSG00000169252,ENSG00000196924,ENSG00000111537,ENSG00000232810,ENSG00000134308,ENSG00000111640,ENSG00000116288,ENSG00000175793,ENSG00000187446,ENSG00000130402,ENSG00000170312,ENSG00000122223,ENSG00000185651,ENSG00000169230,ENSG00000041353,ENSG00000167723,ENSG00000204472,ENSG00000116030,ENSG00000166710,ENSG00000163823,ENSG00000147065,ENSG00000105220,ENSG00000158869,ENSG00000163131,ENSG00000100385,ENSG00000132932,ENSG00000133026,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000148175,ENSG00000141736,ENSG00000204592,ENSG00000157873,ENSG00000198843,ENSG00000070831,ENSG00000075624,ENSG00000096968,ENSG00000170837,ENSG00000165527,ENSG00000123338,ENSG00000128272,ENSG00000114126,ENSG00000139998,ENSG00000160255,ENSG00000213366,ENSG00000150756,ENSG00000137312,ENSG00000147168,ENSG00000169223,ENSG00000155096,ENSG00000110218 |
| GO:0052547 | regulation of peptidase activity | 0.0092394 | 461 | 712 | 34 | 0.0477528 | 0.0737527 | GO:BP | ENSG00000092010,ENSG00000126709,ENSG00000117560,ENSG00000100911,ENSG00000117984,ENSG00000138795,ENSG00000232810,ENSG00000204397,ENSG00000111640,ENSG00000116288,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000204264,ENSG00000077984,ENSG00000163359,ENSG00000169230,ENSG00000153094,ENSG00000089685,ENSG00000021355,ENSG00000196954,ENSG00000105220,ENSG00000136717,ENSG00000071994,ENSG00000067560,ENSG00000168961,ENSG00000096968,ENSG00000055163,ENSG00000132386,ENSG00000142867,ENSG00000126432,ENSG00000254087,ENSG00000177076,ENSG00000147889 |
| GO:1901857 | positive regulation of cellular respiration | 0.0092747 | 10 | 712 | 4 | 0.0056180 | 0.4000000 | GO:BP | ENSG00000111537,ENSG00000116288,ENSG00000170312,ENSG00000169230 |
| GO:0002218 | activation of innate immune response | 0.0092747 | 318 | 712 | 26 | 0.0365169 | 0.0817610 | GO:BP | ENSG00000092010,ENSG00000125347,ENSG00000135077,ENSG00000155629,ENSG00000100911,ENSG00000170315,ENSG00000137265,ENSG00000134321,ENSG00000204264,ENSG00000213281,ENSG00000166598,ENSG00000158869,ENSG00000163131,ENSG00000185507,ENSG00000115267,ENSG00000162676,ENSG00000172936,ENSG00000164164,ENSG00000127666,ENSG00000142867,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000137312,ENSG00000132256,ENSG00000175104 |
| GO:0050851 | antigen receptor-mediated signaling pathway | 0.0092747 | 318 | 712 | 26 | 0.0365169 | 0.0817610 | GO:BP | ENSG00000004468,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000163599,ENSG00000196735,ENSG00000159216,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000160654,ENSG00000186470,ENSG00000117228,ENSG00000204264,ENSG00000211810,ENSG00000198821,ENSG00000165283,ENSG00000167286,ENSG00000123338,ENSG00000142867,ENSG00000041357,ENSG00000254087,ENSG00000101082,ENSG00000198851,ENSG00000196839,ENSG00000175104 |
| GO:0043069 | negative regulation of programmed cell death | 0.0092747 | 948 | 712 | 59 | 0.0828652 | 0.0622363 | GO:BP | ENSG00000004468,ENSG00000113721,ENSG00000126709,ENSG00000163421,ENSG00000019582,ENSG00000117560,ENSG00000119917,ENSG00000164111,ENSG00000170315,ENSG00000105639,ENSG00000196924,ENSG00000118193,ENSG00000150093,ENSG00000172757,ENSG00000138795,ENSG00000232810,ENSG00000183691,ENSG00000204397,ENSG00000108179,ENSG00000134352,ENSG00000116288,ENSG00000249437,ENSG00000175793,ENSG00000156463,ENSG00000071205,ENSG00000170312,ENSG00000164830,ENSG00000141576,ENSG00000070018,ENSG00000055332,ENSG00000169230,ENSG00000065135,ENSG00000119335,ENSG00000148400,ENSG00000204472,ENSG00000089685,ENSG00000044574,ENSG00000163545,ENSG00000166598,ENSG00000118971,ENSG00000074800,ENSG00000105220,ENSG00000158869,ENSG00000158006,ENSG00000100385,ENSG00000067560,ENSG00000185507,ENSG00000103495,ENSG00000104765,ENSG00000172936,ENSG00000178719,ENSG00000096968,ENSG00000168329,ENSG00000123338,ENSG00000142867,ENSG00000126432,ENSG00000196839,ENSG00000137193,ENSG00000175104 |
| GO:0002791 | regulation of peptide secretion | 0.0092747 | 536 | 712 | 38 | 0.0533708 | 0.0708955 | GO:BP | ENSG00000004468,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000135077,ENSG00000155657,ENSG00000182054,ENSG00000019582,ENSG00000164111,ENSG00000110090,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000204397,ENSG00000111640,ENSG00000134321,ENSG00000122223,ENSG00000117394,ENSG00000204472,ENSG00000089685,ENSG00000118263,ENSG00000021355,ENSG00000105220,ENSG00000133026,ENSG00000115267,ENSG00000168961,ENSG00000204592,ENSG00000157873,ENSG00000198843,ENSG00000111863,ENSG00000096968,ENSG00000170837,ENSG00000165527,ENSG00000102931,ENSG00000254087,ENSG00000028137,ENSG00000175104,ENSG00000110218 |
| GO:0000904 | cell morphogenesis involved in differentiation | 0.0095635 | 769 | 712 | 50 | 0.0702247 | 0.0650195 | GO:BP | ENSG00000072110,ENSG00000179218,ENSG00000147459,ENSG00000198513,ENSG00000173482,ENSG00000091129,ENSG00000221866,ENSG00000117632,ENSG00000196924,ENSG00000118193,ENSG00000150093,ENSG00000167461,ENSG00000125249,ENSG00000172757,ENSG00000138795,ENSG00000179051,ENSG00000183691,ENSG00000117228,ENSG00000139626,ENSG00000103769,ENSG00000137474,ENSG00000169855,ENSG00000130402,ENSG00000163359,ENSG00000061337,ENSG00000148400,ENSG00000171246,ENSG00000118263,ENSG00000173786,ENSG00000073803,ENSG00000138071,ENSG00000067560,ENSG00000132932,ENSG00000133026,ENSG00000149294,ENSG00000172270,ENSG00000122877,ENSG00000173517,ENSG00000141736,ENSG00000158321,ENSG00000070831,ENSG00000079691,ENSG00000132670,ENSG00000075624,ENSG00000197956,ENSG00000055163,ENSG00000137312,ENSG00000139926,ENSG00000169554,ENSG00000111859 |
| GO:0002230 | positive regulation of defense response to virus by host | 0.0096493 | 26 | 712 | 6 | 0.0084270 | 0.2307692 | GO:BP | ENSG00000138496,ENSG00000163840,ENSG00000115415,ENSG00000096996,ENSG00000239713,ENSG00000128394 |
| GO:0048285 | organelle fission | 0.0097521 | 463 | 712 | 34 | 0.0477528 | 0.0734341 | GO:BP | ENSG00000148773,ENSG00000113721,ENSG00000117724,ENSG00000179218,ENSG00000155657,ENSG00000101057,ENSG00000170315,ENSG00000156970,ENSG00000196924,ENSG00000118193,ENSG00000112029,ENSG00000138160,ENSG00000126787,ENSG00000103769,ENSG00000100918,ENSG00000011426,ENSG00000153094,ENSG00000157601,ENSG00000089685,ENSG00000204899,ENSG00000138071,ENSG00000122952,ENSG00000143228,ENSG00000067560,ENSG00000113810,ENSG00000131747,ENSG00000070831,ENSG00000066279,ENSG00000136824,ENSG00000109805,ENSG00000121579,ENSG00000116670,ENSG00000124688,ENSG00000134690 |
| GO:0043368 | positive T cell selection | 0.0099022 | 36 | 712 | 7 | 0.0098315 | 0.1944444 | GO:BP | ENSG00000073861,ENSG00000019582,ENSG00000160654,ENSG00000137265,ENSG00000096996,ENSG00000167286,ENSG00000198851 |
| GO:0005737 | cytoplasm | 0.0000000 | 11634 | 739 | 567 | 0.7672530 | 0.0487365 | GO:CC | ENSG00000172057,ENSG00000134824,ENSG00000100453,ENSG00000004468,ENSG00000150687,ENSG00000196169,ENSG00000164308,ENSG00000179344,ENSG00000152217,ENSG00000156587,ENSG00000119922,ENSG00000100450,ENSG00000138496,ENSG00000204267,ENSG00000113721,ENSG00000196126,ENSG00000183688,ENSG00000198826,ENSG00000229474,ENSG00000092010,ENSG00000248905,ENSG00000072110,ENSG00000129595,ENSG00000073605,ENSG00000163599,ENSG00000132530,ENSG00000117724,ENSG00000125347,ENSG00000157423,ENSG00000221963,ENSG00000108679,ENSG00000100321,ENSG00000109956,ENSG00000179218,ENSG00000163492,ENSG00000115523,ENSG00000002834,ENSG00000126709,ENSG00000135077,ENSG00000090857,ENSG00000092068,ENSG00000147459,ENSG00000154451,ENSG00000162654,ENSG00000100427,ENSG00000080573,ENSG00000134184,ENSG00000155657,ENSG00000163840,ENSG00000057704,ENSG00000097021,ENSG00000196735,ENSG00000182054,ENSG00000123485,ENSG00000231925,ENSG00000019582,ENSG00000142669,ENSG00000117560,ENSG00000144354,ENSG00000198513,ENSG00000072135,ENSG00000164649,ENSG00000151502,ENSG00000160014,ENSG00000034510,ENSG00000173482,ENSG00000130164,ENSG00000127124,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000155629,ENSG00000186469,ENSG00000069702,ENSG00000100911,ENSG00000164111,ENSG00000177156,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000166503,ENSG00000156970,ENSG00000171848,ENSG00000213512,ENSG00000125868,ENSG00000105639,ENSG00000125864,ENSG00000117632,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000118193,ENSG00000112029,ENSG00000065911,ENSG00000117984,ENSG00000127947,ENSG00000150093,ENSG00000136167,ENSG00000121039,ENSG00000167461,ENSG00000105409,ENSG00000123609,ENSG00000173848,ENSG00000138160,ENSG00000165617,ENSG00000172331,ENSG00000125249,ENSG00000149328,ENSG00000133321,ENSG00000172757,ENSG00000138795,ENSG00000110090,ENSG00000102554,ENSG00000111885,ENSG00000179051,ENSG00000123179,ENSG00000112139,ENSG00000099194,ENSG00000232810,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000126787,ENSG00000171202,ENSG00000176890,ENSG00000133739,ENSG00000100749,ENSG00000108179,ENSG00000111640,ENSG00000118777,ENSG00000183734,ENSG00000172292,ENSG00000167914,ENSG00000103769,ENSG00000100380,ENSG00000108518,ENSG00000128335,ENSG00000117226,ENSG00000128284,ENSG00000131171,ENSG00000005844,ENSG00000103148,ENSG00000084092,ENSG00000167123,ENSG00000137474,ENSG00000116288,ENSG00000196230,ENSG00000134765,ENSG00000180644,ENSG00000103202,ENSG00000122121,ENSG00000073008,ENSG00000213390,ENSG00000135114,ENSG00000134321,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000103966,ENSG00000023572,ENSG00000142794,ENSG00000152465,ENSG00000172508,ENSG00000143543,ENSG00000137563,ENSG00000138642,ENSG00000106392,ENSG00000204264,ENSG00000173821,ENSG00000143742,ENSG00000157045,ENSG00000051341,ENSG00000131018,ENSG00000205413,ENSG00000196976,ENSG00000136274,ENSG00000188191,ENSG00000077984,ENSG00000114978,ENSG00000187446,ENSG00000130402,ENSG00000188312,ENSG00000011426,ENSG00000071205,ENSG00000170312,ENSG00000170222,ENSG00000105887,ENSG00000110060,ENSG00000155846,ENSG00000136436,ENSG00000163359,ENSG00000185651,ENSG00000164830,ENSG00000141576,ENSG00000117394,ENSG00000172116,ENSG00000135069,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000165949,ENSG00000185304,ENSG00000152969,ENSG00000092853,ENSG00000061337,ENSG00000215305,ENSG00000055332,ENSG00000239713,ENSG00000242372,ENSG00000169230,ENSG00000153094,ENSG00000123416,ENSG00000152229,ENSG00000065135,ENSG00000213445,ENSG00000104687,ENSG00000213281,ENSG00000171451,ENSG00000164919,ENSG00000110080,ENSG00000123131,ENSG00000159200,ENSG00000122971,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000164211,ENSG00000041353,ENSG00000089127,ENSG00000152256,ENSG00000204472,ENSG00000171130,ENSG00000184007,ENSG00000089685,ENSG00000189159,ENSG00000044574,ENSG00000124587,ENSG00000171246,ENSG00000130741,ENSG00000116030,ENSG00000064666,ENSG00000233954,ENSG00000072958,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000111229,ENSG00000073803,ENSG00000104805,ENSG00000179632,ENSG00000163545,ENSG00000152778,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000166974,ENSG00000204899,ENSG00000128578,ENSG00000180667,ENSG00000129422,ENSG00000166197,ENSG00000204822,ENSG00000154001,ENSG00000126016,ENSG00000241258,ENSG00000206127,ENSG00000253626,ENSG00000073910,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000157985,ENSG00000107317,ENSG00000111348,ENSG00000137959,ENSG00000132661,ENSG00000148730,ENSG00000100342,ENSG00000108798,ENSG00000129675,ENSG00000112031,ENSG00000118971,ENSG00000084090,ENSG00000177150,ENSG00000021355,ENSG00000196954,ENSG00000183475,ENSG00000115155,ENSG00000093009,ENSG00000101444,ENSG00000185650,ENSG00000100605,ENSG00000125871,ENSG00000111331,ENSG00000074800,ENSG00000143476,ENSG00000084623,ENSG00000172803,ENSG00000122952,ENSG00000105220,ENSG00000143228,ENSG00000181467,ENSG00000158869,ENSG00000196449,ENSG00000172164,ENSG00000136717,ENSG00000071994,ENSG00000168421,ENSG0000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| GO:0005622 | intracellular | 0.0000000 | 14626 | 739 | 655 | 0.8863329 | 0.0447833 | GO:CC | 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ENSG00000103489,ENSG00000011007,ENSG00000154518,ENSG00000028137,ENSG00000160753,ENSG00000178685,ENSG00000169223,ENSG00000132256,ENSG00000111481,ENSG00000147889,ENSG00000139926,ENSG00000140575,ENSG00000137193,ENSG00000160404,ENSG00000111450,ENSG00000155096,ENSG00000175104,ENSG00000078124,ENSG00000196642,ENSG00000110218,ENSG00000169554,ENSG00000127084,ENSG00000120280,ENSG00000113387,ENSG00000166794,ENSG00000114631,ENSG00000111859,ENSG00000147180,ENSG00000170485,ENSG00000130818 |
| GO:0031982 | vesicle | 0.0000000 | 3914 | 739 | 236 | 0.3193505 | 0.0602964 | GO:CC | ENSG00000172057,ENSG00000004468,ENSG00000150687,ENSG00000179344,ENSG00000204267,ENSG00000113721,ENSG00000196126,ENSG00000092010,ENSG00000072110,ENSG00000163599,ENSG00000108679,ENSG00000100321,ENSG00000179218,ENSG00000115523,ENSG00000159674,ENSG00000135077,ENSG00000154451,ENSG00000162654,ENSG00000100427,ENSG00000155657,ENSG00000163840,ENSG00000097021,ENSG00000196735,ENSG00000182054,ENSG00000231925,ENSG00000019582,ENSG00000142669,ENSG00000117560,ENSG00000203747,ENSG00000151502,ENSG00000160014,ENSG00000130164,ENSG00000143870,ENSG00000186469,ENSG00000069702,ENSG00000100911,ENSG00000205336,ENSG00000164111,ENSG00000177156,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000125868,ENSG00000105639,ENSG00000117632,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000117984,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000105409,ENSG00000172331,ENSG00000125249,ENSG00000172757,ENSG00000111885,ENSG00000179051,ENSG00000232810,ENSG00000117228,ENSG00000134308,ENSG00000111640,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000103769,ENSG00000100380,ENSG00000108518,ENSG00000117226,ENSG00000131171,ENSG00000005844,ENSG00000130592,ENSG00000137474,ENSG00000116288,ENSG00000196230,ENSG00000134765,ENSG00000180644,ENSG00000122121,ENSG00000075234,ENSG00000175793,ENSG00000103966,ENSG00000137563,ENSG00000204264,ENSG00000077984,ENSG00000114978,ENSG00000187446,ENSG00000130402,ENSG00000170312,ENSG00000136436,ENSG00000163359,ENSG00000117394,ENSG00000172116,ENSG00000135069,ENSG00000070018,ENSG00000171603,ENSG00000215305,ENSG00000242372,ENSG00000124299,ENSG00000065135,ENSG00000213445,ENSG00000104687,ENSG00000213281,ENSG00000163520,ENSG00000123131,ENSG00000148400,ENSG00000157601,ENSG00000164211,ENSG00000041353,ENSG00000171130,ENSG00000184007,ENSG00000163041,ENSG00000044574,ENSG00000171246,ENSG00000130741,ENSG00000064666,ENSG00000072958,ENSG00000173786,ENSG00000166710,ENSG00000111229,ENSG00000104805,ENSG00000147065,ENSG00000126016,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000107317,ENSG00000111348,ENSG00000021355,ENSG00000115155,ENSG00000101444,ENSG00000074800,ENSG00000084623,ENSG00000172803,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000136717,ENSG00000071994,ENSG00000155368,ENSG00000100299,ENSG00000134909,ENSG00000163131,ENSG00000100385,ENSG00000131504,ENSG00000067560,ENSG00000132932,ENSG00000213719,ENSG00000213064,ENSG00000134202,ENSG00000172794,ENSG00000075340,ENSG00000133026,ENSG00000174684,ENSG00000185507,ENSG00000204642,ENSG00000143727,ENSG00000006625,ENSG00000115339,ENSG00000115902,ENSG00000172270,ENSG00000148175,ENSG00000141736,ENSG00000204592,ENSG00000083444,ENSG00000002549,ENSG00000167286,ENSG00000130812,ENSG00000042753,ENSG00000153310,ENSG00000178996,ENSG00000070831,ENSG00000079691,ENSG00000172936,ENSG00000101079,ENSG00000171302,ENSG00000147234,ENSG00000197043,ENSG00000132670,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000075239,ENSG00000136824,ENSG00000165527,ENSG00000105612,ENSG00000127666,ENSG00000139370,ENSG00000127022,ENSG00000197956,ENSG00000121579,ENSG00000055163,ENSG00000132386,ENSG00000123338,ENSG00000010270,ENSG00000140450,ENSG00000134049,ENSG00000143740,ENSG00000126432,ENSG00000124155,ENSG00000144043,ENSG00000196834,ENSG00000172531,ENSG00000129968,ENSG00000140284,ENSG00000041357,ENSG00000125354,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000092841,ENSG00000213366,ENSG00000140319,ENSG00000127951,ENSG00000155660,ENSG00000101082,ENSG00000197409,ENSG00000137312,ENSG00000196839,ENSG00000132388,ENSG00000148218,ENSG00000242574,ENSG00000147168,ENSG00000177674,ENSG00000028137,ENSG00000160753,ENSG00000169223,ENSG00000111481,ENSG00000140575,ENSG00000111450,ENSG00000175104,ENSG00000113387,ENSG00000166794 |
| GO:0043227 | membrane-bounded organelle | 0.0000000 | 12584 | 739 | 580 | 0.7848444 | 0.0460903 | GO:CC | ENSG00000172057,ENSG00000134824,ENSG00000100453,ENSG00000004468,ENSG00000150687,ENSG00000148773,ENSG00000164308,ENSG00000179344,ENSG00000152217,ENSG00000156587,ENSG00000119922,ENSG00000138496,ENSG00000204267,ENSG00000113721,ENSG00000176083,ENSG00000196126,ENSG00000229474,ENSG00000092010,ENSG00000248905,ENSG00000072110,ENSG00000073861,ENSG00000163599,ENSG00000132530,ENSG00000117724,ENSG00000125347,ENSG00000108679,ENSG00000100321,ENSG00000109956,ENSG00000179218,ENSG00000115523,ENSG00000126709,ENSG00000159674,ENSG00000184357,ENSG00000135077,ENSG00000090857,ENSG00000165891,ENSG00000154451,ENSG00000162654,ENSG00000100427,ENSG00000080573,ENSG00000155657,ENSG00000163840,ENSG00000057704,ENSG00000097021,ENSG00000196735,ENSG00000182054,ENSG00000123485,ENSG00000231925,ENSG00000019582,ENSG00000142669,ENSG00000117560,ENSG00000144354,ENSG00000198513,ENSG00000072135,ENSG00000164649,ENSG00000203747,ENSG00000159216,ENSG00000151502,ENSG00000160014,ENSG00000130164,ENSG00000127124,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000186469,ENSG00000069702,ENSG00000100911,ENSG00000197928,ENSG00000130511,ENSG00000205336,ENSG00000164111,ENSG00000124191,ENSG00000198046,ENSG00000113368,ENSG00000101057,ENSG00000177156,ENSG00000163029,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000166503,ENSG00000156970,ENSG00000213512,ENSG00000125868,ENSG00000105639,ENSG00000117632,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000175550,ENSG00000118193,ENSG00000112029,ENSG00000065911,ENSG00000117984,ENSG00000127947,ENSG00000157216,ENSG00000150093,ENSG00000136167,ENSG00000121039,ENSG00000167461,ENSG00000105409,ENSG00000123609,ENSG00000165512,ENSG00000173848,ENSG00000138160,ENSG00000077312,ENSG00000165617,ENSG00000172331,ENSG00000125249,ENSG00000149328,ENSG00000111206,ENSG00000172757,ENSG00000138795,ENSG00000110090,ENSG00000102554,ENSG00000111885,ENSG00000179051,ENSG00000123179,ENSG00000112139,ENSG00000189430,ENSG00000099194,ENSG00000232810,ENSG00000117228,ENSG00000134308,ENSG00000126787,ENSG00000171202,ENSG00000176890,ENSG00000176293,ENSG00000100749,ENSG00000108179,ENSG00000111640,ENSG00000118777,ENSG00000183734,ENSG00000172292,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000103769,ENSG00000100380,ENSG00000108518,ENSG00000128335,ENSG00000117226,ENSG00000183741,ENSG00000131171,ENSG00000189319,ENSG00000005844,ENSG00000130592,ENSG00000103148,ENSG00000084092,ENSG00000167123,ENSG00000137474,ENSG00000116288,ENSG00000196230,ENSG00000134765,ENSG00000103512,ENSG00000180644,ENSG00000111602,ENSG00000103202,ENSG00000122121,ENSG00000075234,ENSG00000213390,ENSG00000135114,ENSG00000134321,ENSG00000175793,ENSG00000169855,ENSG00000103966,ENSG00000124575,ENSG00000189420,ENSG00000023572,ENSG00000100918,ENSG00000152465,ENSG00000156463,ENSG00000143543,ENSG00000137563,ENSG00000138642,ENSG00000106392,ENSG00000204264,ENSG00000173821,ENSG00000143742,ENSG00000105011,ENSG00000157045,ENSG00000051341,ENSG00000131018,ENSG00000205413,ENSG00000196976,ENSG00000136274,ENSG00000077984,ENSG00000114978,ENSG00000187446,ENSG00000130402,ENSG00000188312,ENSG00000011426,ENSG00000170312,ENSG00000105887,ENSG00000110060,ENSG00000155846,ENSG00000136436,ENSG00000163359,ENSG00000185651,ENSG00000164830,ENSG00000117394,ENSG00000172116,ENSG00000135069,ENSG00000131944,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000125462,ENSG00000165949,ENSG00000185304,ENSG00000099840,ENSG00000092853,ENSG00000215305,ENSG00000055332,ENSG00000239713,ENSG00000242372,ENSG00000169230,ENSG00000124299,ENSG00000153094,ENSG00000065135,ENSG00000213445,ENSG00000104687,ENSG00000213281,ENSG00000171451,ENSG00000163520,ENSG00000164919,ENSG00000110080,ENSG00000123131,ENSG00000159200,ENSG00000122971,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000164211,ENSG00000041353,ENSG00000089127,ENSG00000152256,ENSG00000204472,ENSG00000171130,ENSG00000184007,ENSG00000089685,ENSG00000189159,ENSG00000121297,ENSG00000163041,ENSG00000044574,ENSG00000133315,ENSG00000124587,ENSG00000188612,ENSG00000171246,ENSG00000181938,ENSG00000130741,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000233954,ENSG00000072958,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000111229,ENSG00000104805,ENSG00000179632,ENSG00000163545,ENSG00000147065,ENSG00000142556,ENSG00000166454,ENSG00000129422,ENSG00000166197,ENSG00000204822,ENSG00000154001,ENSG00000126016,ENSG00000241258,ENSG00000206127,ENSG00000253626,ENSG00000131931,ENSG00000171970,ENSG00000138071,ENSG00000100897,ENSG00000166598,ENSG00000131236,ENSG00000157985,ENSG00000107317,ENSG00000111348,ENSG00000132661,ENSG00000100342,ENSG00000225921,ENSG00000112031,ENSG00000118971,ENSG00000129534,ENSG00000084090,ENSG00000177150,ENSG00000021355,ENSG00000196954,ENSG00000177613,ENSG00000115155,ENSG00000093009,ENSG00000101444,ENSG00000185650,ENSG00000125871,ENSG00000111331,ENSG00000074800,ENSG00000143476,ENSG00000084623,ENSG00000172803,ENSG00000122952,ENSG00000105220,ENSG00000143228,ENSG00000181467,ENSG00000158869,ENSG00000171222,ENSG00000196449,ENSG00000053254,ENSG00000145649,ENSG00000136717,ENSG00000071994,ENSG00000155368,ENSG00000100299,ENSG00000134909,ENSG00000158006,ENSG00000163131,ENSG00000170881,ENSG00000100385,ENSG00000130005,ENSG00000125148,ENSG00000139921,ENSG00000131504,ENSG00000128039,ENSG00000134490,ENSG00000011485,ENSG00000067560,ENSG00000196436,ENSG00000132932,ENSG00000213928,ENSG00000125944,ENSG00000127952,ENSG00000183172,ENSG00000114166,ENSG00000049449,ENSG00000189283,ENSG00000213719,ENSG00000213064,ENSG00000165304,ENSG00000134202,ENSG00000172794,ENSG00000075340,ENSG00000133026,ENSG00000174684,ENSG00000113810,ENSG00000115520,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000144597,ENSG00000204642,ENSG00000115267,ENSG00000204256,ENSG00000143727,ENSG00000087302,ENSG00000006625,ENSG00000101474,ENSG00000168961,ENSG00000115339,ENSG00000115902,ENSG00000122122,ENSG00000158882,ENSG00000180938,ENSG00000172270,ENSG00000122877,ENSG00000165283,ENSG00000172795,ENSG00000148175,ENSG00000131747,ENSG00000171617,ENSG00000141736,ENSG00000132963,ENSG00000162702,ENSG00000204592,ENSG00000132182,ENSG00000132792,ENSG00000083444,ENSG00000103994,ENSG00000158321,ENSG00000237190,ENSG00000174371,ENSG00000116771,ENSG00000160877,ENSG00000002549,ENSG00000129625,ENSG00000213626,ENSG00000166881,ENSG00000167286,ENSG00000187608,ENSG00000021762,ENSG00000130812,ENSG00000198843,ENSG00000139579,ENSG00000103495,ENSG00000162676,ENSG00000068489,ENSG00000106462,ENSG00000042753,ENSG00000153310,ENSG00000178996,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000152253,ENSG00000079691,ENSG00000172936,ENSG00000112996,ENSG00000124920,ENSG00000170860,ENSG00000171169,ENSG00000101079,ENSG00000118705,ENSG00000164088,ENSG00000243660,ENSG00000128294,ENSG00000179583,ENSG00000171302,ENSG00000178719,ENSG00000166035,ENSG00000141030,ENSG00000074071,ENSG00000147234,ENSG00000197142,ENSG00000197043,ENSG00000189266,ENSG00000132670,ENSG00000066279,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000176542,ENSG00000128394,ENSG00000075239,ENSG00000176641,ENSG00000130348,ENSG00000109674,ENSG00000136824,ENSG00000079999,ENSG00000165527,ENSG00000117155,ENSG00000105612,ENSG00000162385,ENSG00000171954,ENSG00000127666,ENSG00000159111,ENSG00000139370,ENSG00000109084,ENSG00000223496,ENSG00000127022,ENSG00000197956,ENSG00000109805,ENSG00000026751,ENSG00000121579,ENSG00000138018,ENSG00000148908,ENSG00000196072,ENSG00000138617,ENSG00000184897,ENSG00000102931,ENSG00000125648,ENSG00000116670,ENSG00000184154,ENSG00000055163,ENSG00000185880,ENSG00000090520,ENSG00000132386,ENSG00000049239,ENSG00000127774,ENSG00000123338,ENSG00000010270,ENSG00000109536,ENSG00000140450,ENSG00000128272,ENSG00000134049,ENSG00000148337,ENSG00000124688,ENSG00000120709,ENSG00000142867,ENSG00000111335,ENSG00000114126,ENSG00000109390,ENSG00000143740,ENSG00000126432,ENSG00000124155,ENSG00000214022,ENSG00000198736,ENSG00000145337,ENSG00000144043,ENSG00000049541,ENSG00000196834,ENSG00000175283,ENSG00000104738,ENSG00000119318,ENSG00000172531,ENSG00000178691,ENSG00000129968,ENSG00000257390,ENSG00000153044,ENSG00000140284,ENSG00000137309,ENSG00000006756,ENSG00000041357,ENSG00000125354,ENSG00000125870,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000152601,ENSG00000189306,ENSG00000104472,ENSG00000066583,ENSG00000092841,ENSG00000091127,ENSG00000213366,ENSG00000140319,ENSG00000183726,ENSG00000177076,ENSG00000127951,ENSG00000137310,ENSG00000155660,ENSG00000101082,ENSG00000164576,ENSG00000197409,ENSG00000172667,ENSG00000150756,ENSG00000131873,ENSG00000173660,ENSG00000137312,ENSG00000196839,ENSG00000132388,ENSG00000143321,ENSG00000136104,ENSG00000089693,ENSG00000232838,ENSG00000155090,ENSG00000148218,ENSG00000242574,ENSG00000147168,ENSG00000134690,ENSG00000184575,ENSG00000177674,ENSG00000103489,ENSG00000011007,ENSG00000154518,ENSG00000028137,ENSG00000160753,ENSG00000178685,ENSG00000169223,ENSG00000132256,ENSG00000111481,ENSG00000147889,ENSG00000140575,ENSG00000137193,ENSG00000160404,ENSG00000111450,ENSG00000155096,ENSG00000175104,ENSG00000078124,ENSG00000196642,ENSG00000110218,ENSG00000169554,ENSG00000127084,ENSG00000120280,ENSG00000113387,ENSG00000166794,ENSG00000114631,ENSG00000111859,ENSG00000147180,ENSG00000170485,ENSG00000130818 |
| GO:0043230 | extracellular organelle | 0.0000000 | 2172 | 739 | 150 | 0.2029770 | 0.0690608 | GO:CC | ENSG00000004468,ENSG00000150687,ENSG00000196126,ENSG00000092010,ENSG00000072110,ENSG00000108679,ENSG00000179218,ENSG00000159674,ENSG00000162654,ENSG00000155657,ENSG00000097021,ENSG00000182054,ENSG00000019582,ENSG00000142669,ENSG00000117560,ENSG00000203747,ENSG00000143870,ENSG00000186469,ENSG00000069702,ENSG00000100911,ENSG00000205336,ENSG00000164111,ENSG00000177156,ENSG00000170315,ENSG00000213512,ENSG00000125868,ENSG00000117632,ENSG00000167004,ENSG00000196924,ENSG00000117984,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000105409,ENSG00000172331,ENSG00000172757,ENSG00000111885,ENSG00000134308,ENSG00000111640,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000103769,ENSG00000100380,ENSG00000108518,ENSG00000131171,ENSG00000005844,ENSG00000130592,ENSG00000116288,ENSG00000196230,ENSG00000134765,ENSG00000122121,ENSG00000075234,ENSG00000175793,ENSG00000103966,ENSG00000137563,ENSG00000204264,ENSG00000114978,ENSG00000187446,ENSG00000130402,ENSG00000170312,ENSG00000163359,ENSG00000117394,ENSG00000135069,ENSG00000242372,ENSG00000124299,ENSG00000065135,ENSG00000104687,ENSG00000213281,ENSG00000163520,ENSG00000123131,ENSG00000041353,ENSG00000163041,ENSG00000044574,ENSG00000130741,ENSG00000072958,ENSG00000173786,ENSG00000166710,ENSG00000111229,ENSG00000104805,ENSG00000147065,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000107317,ENSG00000111348,ENSG00000021355,ENSG00000101444,ENSG00000074800,ENSG00000084623,ENSG00000105220,ENSG00000181467,ENSG00000071994,ENSG00000155368,ENSG00000100299,ENSG00000067560,ENSG00000213719,ENSG00000213064,ENSG00000134202,ENSG00000133026,ENSG00000174684,ENSG00000143727,ENSG00000006625,ENSG00000115339,ENSG00000115902,ENSG00000172270,ENSG00000148175,ENSG00000204592,ENSG00000083444,ENSG00000002549,ENSG00000130812,ENSG00000153310,ENSG00000178996,ENSG00000070831,ENSG00000079691,ENSG00000101079,ENSG00000171302,ENSG00000197043,ENSG00000132670,ENSG00000075624,ENSG00000075239,ENSG00000136824,ENSG00000165527,ENSG00000105612,ENSG00000127022,ENSG00000197956,ENSG00000121579,ENSG00000055163,ENSG00000132386,ENSG00000123338,ENSG00000140450,ENSG00000126432,ENSG00000196834,ENSG00000172531,ENSG00000140284,ENSG00000041357,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000092841,ENSG00000213366,ENSG00000127951,ENSG00000197409,ENSG00000137312,ENSG00000132388,ENSG00000148218,ENSG00000169223,ENSG00000140575,ENSG00000113387,ENSG00000166794 |
| GO:1903561 | extracellular vesicle | 0.0000000 | 2167 | 739 | 148 | 0.2002706 | 0.0682972 | GO:CC | ENSG00000004468,ENSG00000150687,ENSG00000196126,ENSG00000092010,ENSG00000072110,ENSG00000108679,ENSG00000179218,ENSG00000159674,ENSG00000155657,ENSG00000097021,ENSG00000182054,ENSG00000019582,ENSG00000142669,ENSG00000117560,ENSG00000203747,ENSG00000143870,ENSG00000186469,ENSG00000069702,ENSG00000100911,ENSG00000205336,ENSG00000164111,ENSG00000177156,ENSG00000170315,ENSG00000125868,ENSG00000117632,ENSG00000167004,ENSG00000196924,ENSG00000117984,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000105409,ENSG00000172331,ENSG00000172757,ENSG00000111885,ENSG00000134308,ENSG00000111640,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000103769,ENSG00000100380,ENSG00000108518,ENSG00000131171,ENSG00000005844,ENSG00000130592,ENSG00000116288,ENSG00000196230,ENSG00000134765,ENSG00000122121,ENSG00000075234,ENSG00000175793,ENSG00000103966,ENSG00000137563,ENSG00000204264,ENSG00000114978,ENSG00000187446,ENSG00000130402,ENSG00000170312,ENSG00000163359,ENSG00000117394,ENSG00000135069,ENSG00000242372,ENSG00000124299,ENSG00000065135,ENSG00000104687,ENSG00000213281,ENSG00000163520,ENSG00000123131,ENSG00000041353,ENSG00000163041,ENSG00000044574,ENSG00000130741,ENSG00000072958,ENSG00000173786,ENSG00000166710,ENSG00000111229,ENSG00000104805,ENSG00000147065,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000107317,ENSG00000111348,ENSG00000021355,ENSG00000101444,ENSG00000074800,ENSG00000084623,ENSG00000105220,ENSG00000181467,ENSG00000071994,ENSG00000155368,ENSG00000100299,ENSG00000067560,ENSG00000213719,ENSG00000213064,ENSG00000134202,ENSG00000133026,ENSG00000174684,ENSG00000143727,ENSG00000006625,ENSG00000115339,ENSG00000115902,ENSG00000172270,ENSG00000148175,ENSG00000204592,ENSG00000083444,ENSG00000002549,ENSG00000130812,ENSG00000153310,ENSG00000178996,ENSG00000070831,ENSG00000079691,ENSG00000101079,ENSG00000171302,ENSG00000197043,ENSG00000132670,ENSG00000075624,ENSG00000075239,ENSG00000136824,ENSG00000165527,ENSG00000105612,ENSG00000127022,ENSG00000197956,ENSG00000121579,ENSG00000055163,ENSG00000132386,ENSG00000123338,ENSG00000140450,ENSG00000126432,ENSG00000196834,ENSG00000172531,ENSG00000140284,ENSG00000041357,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000092841,ENSG00000213366,ENSG00000127951,ENSG00000197409,ENSG00000137312,ENSG00000132388,ENSG00000148218,ENSG00000169223,ENSG00000140575,ENSG00000113387,ENSG00000166794 |
| GO:0098552 | side of membrane | 0.0000000 | 603 | 739 | 61 | 0.0825440 | 0.1011609 | GO:CC | ENSG00000179344,ENSG00000196126,ENSG00000163599,ENSG00000179218,ENSG00000089692,ENSG00000181036,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000117560,ENSG00000203747,ENSG00000130164,ENSG00000186469,ENSG00000069702,ENSG00000091129,ENSG00000164111,ENSG00000223865,ENSG00000231389,ENSG00000160654,ENSG00000186470,ENSG00000150093,ENSG00000096996,ENSG00000211698,ENSG00000232810,ENSG00000134539,ENSG00000118777,ENSG00000134352,ENSG00000153563,ENSG00000122223,ENSG00000065135,ENSG00000104687,ENSG00000166710,ENSG00000104805,ENSG00000163823,ENSG00000126016,ENSG00000110448,ENSG00000158869,ENSG00000100299,ENSG00000013725,ENSG00000100385,ENSG00000067560,ENSG00000149294,ENSG00000204642,ENSG00000143727,ENSG00000204592,ENSG00000167286,ENSG00000157873,ENSG00000178996,ENSG00000168329,ENSG00000127022,ENSG00000197956,ENSG00000254087,ENSG00000160255,ENSG00000131019,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000147168,ENSG00000140575,ENSG00000175104,ENSG00000081985 |
| GO:0043226 | organelle | 0.0000000 | 13720 | 739 | 613 | 0.8294993 | 0.0446793 | GO:CC | ENSG00000172057,ENSG00000134824,ENSG00000100453,ENSG00000004468,ENSG00000150687,ENSG00000196169,ENSG00000148773,ENSG00000164308,ENSG00000179344,ENSG00000152217,ENSG00000156587,ENSG00000119922,ENSG00000138496,ENSG00000204267,ENSG00000113721,ENSG00000176083,ENSG00000196126,ENSG00000183688,ENSG00000229474,ENSG00000092010,ENSG00000248905,ENSG00000072110,ENSG00000129595,ENSG00000073861,ENSG00000163599,ENSG00000132530,ENSG00000117724,ENSG00000125347,ENSG00000157423,ENSG00000108679,ENSG00000100321,ENSG00000109956,ENSG00000179218,ENSG00000163492,ENSG00000115523,ENSG00000002834,ENSG00000126709,ENSG00000159674,ENSG00000184357,ENSG00000135077,ENSG00000090857,ENSG00000165891,ENSG00000154451,ENSG00000162654,ENSG00000100427,ENSG00000080573,ENSG00000155657,ENSG00000163840,ENSG00000057704,ENSG00000097021,ENSG00000196735,ENSG00000182054,ENSG00000123485,ENSG00000231925,ENSG00000019582,ENSG00000142669,ENSG00000117560,ENSG00000144354,ENSG00000198513,ENSG00000072135,ENSG00000164649,ENSG00000203747,ENSG00000159216,ENSG00000151502,ENSG00000160014,ENSG00000034510,ENSG00000130164,ENSG00000127124,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000186469,ENSG00000069702,ENSG00000091129,ENSG00000100911,ENSG00000197928,ENSG00000130511,ENSG00000205336,ENSG00000164111,ENSG00000124191,ENSG00000198046,ENSG00000113368,ENSG00000101057,ENSG00000177156,ENSG00000163029,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000166503,ENSG00000156970,ENSG00000213512,ENSG00000125868,ENSG00000105639,ENSG00000125864,ENSG00000117632,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000175550,ENSG00000169442,ENSG00000118193,ENSG00000112029,ENSG00000065911,ENSG00000117984,ENSG00000127947,ENSG00000157216,ENSG00000150093,ENSG00000136167,ENSG00000121039,ENSG00000167461,ENSG00000105409,ENSG00000123609,ENSG00000165512,ENSG00000173848,ENSG00000138160,ENSG00000077312,ENSG00000165617,ENSG00000172331,ENSG00000125249,ENSG00000149328,ENSG00000111206,ENSG00000172757,ENSG00000138795,ENSG00000110090,ENSG00000102554,ENSG00000111885,ENSG00000179051,ENSG00000123179,ENSG00000112139,ENSG00000189430,ENSG00000099194,ENSG00000232810,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000126787,ENSG00000171202,ENSG00000176890,ENSG00000176293,ENSG00000133739,ENSG00000100749,ENSG00000108179,ENSG00000111640,ENSG00000118777,ENSG00000183734,ENSG00000172292,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000103769,ENSG00000100380,ENSG00000108518,ENSG00000128335,ENSG00000117226,ENSG00000183741,ENSG00000131171,ENSG00000189319,ENSG00000005844,ENSG00000130592,ENSG00000103148,ENSG00000084092,ENSG00000167123,ENSG00000137474,ENSG00000116288,ENSG00000196230,ENSG00000134765,ENSG00000103512,ENSG00000180644,ENSG00000111602,ENSG00000103202,ENSG00000122121,ENSG00000075234,ENSG00000213390,ENSG00000135114,ENSG00000134321,ENSG00000175793,ENSG00000169855,ENSG00000103966,ENSG00000124575,ENSG00000189420,ENSG00000023572,ENSG00000100918,ENSG00000152465,ENSG00000156463,ENSG00000143543,ENSG00000137563,ENSG00000138642,ENSG00000106392,ENSG00000204264,ENSG00000173821,ENSG00000143742,ENSG00000105011,ENSG00000157045,ENSG00000051341,ENSG00000131018,ENSG00000205413,ENSG00000196976,ENSG00000136274,ENSG00000188191,ENSG00000077984,ENSG00000114978,ENSG00000187446,ENSG00000130402,ENSG00000188312,ENSG00000011426,ENSG00000170312,ENSG00000105887,ENSG00000110060,ENSG00000155846,ENSG00000136436,ENSG00000163359,ENSG00000185651,ENSG00000164830,ENSG00000117394,ENSG00000172116,ENSG00000135069,ENSG00000131944,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000125462,ENSG00000165949,ENSG00000185304,ENSG00000152969,ENSG00000099840,ENSG00000092853,ENSG00000061337,ENSG00000215305,ENSG00000055332,ENSG00000239713,ENSG00000242372,ENSG00000169230,ENSG00000124299,ENSG00000153094,ENSG00000123416,ENSG00000152229,ENSG00000065135,ENSG00000213445,ENSG00000104687,ENSG00000213281,ENSG00000171451,ENSG00000163520,ENSG00000164919,ENSG00000110080,ENSG00000123131,ENSG00000159200,ENSG00000122971,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000164211,ENSG00000041353,ENSG00000089127,ENSG00000152256,ENSG00000204472,ENSG00000171130,ENSG00000184007,ENSG00000089685,ENSG00000189159,ENSG00000121297,ENSG00000163041,ENSG00000044574,ENSG00000133315,ENSG00000124587,ENSG00000188612,ENSG00000171246,ENSG00000181938,ENSG00000130741,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000233954,ENSG00000072958,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000111229,ENSG00000104805,ENSG00000179632,ENSG00000163545,ENSG00000152778,ENSG00000147065,ENSG00000166974,ENSG00000142556,ENSG00000166454,ENSG00000204899,ENSG00000129422,ENSG00000166197,ENSG00000204822,ENSG00000154001,ENSG00000126016,ENSG00000241258,ENSG00000206127,ENSG00000253626,ENSG00000073910,ENSG00000131931,ENSG00000171970,ENSG00000138071,ENSG00000100897,ENSG00000166598,ENSG00000131236,ENSG00000157985,ENSG00000107317,ENSG00000111348,ENSG00000132661,ENSG00000100342,ENSG00000225921,ENSG00000112031,ENSG00000118971,ENSG00000129534,ENSG00000084090,ENSG00000177150,ENSG00000021355,ENSG00000196954,ENSG00000177613,ENSG00000115155,ENSG00000093009,ENSG00000101444,ENSG00000185650,ENSG00000125871,ENSG00000111331,ENSG00000074800,ENSG00000143476,ENSG00000084623,ENSG00000172803,ENSG00000122952,ENSG00000105220,ENSG00000143228,ENSG00000181467,ENSG00000158869,ENSG00000171222,ENSG00000196449,ENSG00000172164,ENSG00000053254,ENSG00000145649,ENSG00000136717,ENSG00000071994,ENSG00000155368,ENSG00000100299,ENSG00000134909,ENSG00000158006,ENSG00000163131,ENSG00000170881,ENSG00000100385,ENSG00000130005,ENSG00000125148,ENSG00000139921,ENSG00000131504,ENSG00000128039,ENSG00000134490,ENSG00000011485,ENSG00000067560,ENSG00000196436,ENSG00000132932,ENSG00000154027,ENSG00000213928,ENSG00000125944,ENSG00000127952,ENSG00000183172,ENSG00000114166,ENSG00000049449,ENSG00000189283,ENSG00000213719,ENSG00000213064,ENSG00000165304,ENSG00000134202,ENSG00000172794,ENSG00000075340,ENSG00000133026,ENSG00000174684,ENSG00000113810,ENSG00000115520,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000144597,ENSG00000204642,ENSG00000115267,ENSG00000204256,ENSG00000143727,ENSG00000087302,ENSG00000006625,ENSG00000101474,ENSG00000151466,ENSG00000168961,ENSG00000115339,ENSG00000115902,ENSG00000122122,ENSG00000158882,ENSG00000180938,ENSG00000172270,ENSG00000122877,ENSG00000165283,ENSG00000173517,ENSG00000172795,ENSG00000148175,ENSG00000131747,ENSG00000171617,ENSG00000141736,ENSG00000132963,ENSG00000162702,ENSG00000204592,ENSG00000132182,ENSG00000132792,ENSG00000083444,ENSG00000103994,ENSG00000158321,ENSG00000237190,ENSG00000174371,ENSG00000116771,ENSG00000160877,ENSG00000002549,ENSG00000129625,ENSG00000213626,ENSG00000166881,ENSG00000167286,ENSG00000187608,ENSG00000021762,ENSG00000130812,ENSG00000198843,ENSG00000139579,ENSG00000103495,ENSG00000162676,ENSG00000068489,ENSG00000106462,ENSG00000042753,ENSG00000153310,ENSG00000178996,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000152253,ENSG00000079691,ENSG00000172936,ENSG00000112996,ENSG00000124920,ENSG00000170860,ENSG00000171169,ENSG00000151239,ENSG00000101079,ENSG00000118705,ENSG00000164088,ENSG00000243660,ENSG00000128294,ENSG00000179583,ENSG00000171302,ENSG00000153790,ENSG00000178719,ENSG00000166035,ENSG00000141030,ENSG00000074071,ENSG00000147234,ENSG00000197142,ENSG00000197043,ENSG00000189266,ENSG00000132670,ENSG00000066279,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000176542,ENSG00000128394,ENSG00000075239,ENSG00000176641,ENSG00000130348,ENSG00000109674,ENSG00000136824,ENSG00000079999,ENSG00000165527,ENSG00000117155,ENSG00000105612,ENSG00000162385,ENSG00000171954,ENSG00000127666,ENSG00000159111,ENSG00000139370,ENSG00000109084,ENSG00000223496,ENSG00000127022,ENSG00000197956,ENSG00000109805,ENSG00000026751,ENSG00000121579,ENSG00000138018,ENSG00000148908,ENSG00000196072,ENSG00000138617,ENSG00000184897,ENSG00000102931,ENSG00000125648,ENSG00000116670,ENSG00000184154,ENSG00000072571,ENSG00000055163,ENSG00000185880,ENSG00000184640,ENSG00000090520,ENSG00000132386,ENSG00000049239,ENSG00000127774,ENSG00000123338,ENSG00000010270,ENSG00000109536,ENSG00000140450,ENSG00000128272,ENSG00000134049,ENSG00000148337,ENSG00000124688,ENSG00000120709,ENSG00000142867,ENSG00000111335,ENSG00000114126,ENSG00000109390,ENSG00000143740,ENSG00000126432,ENSG00000124155,ENSG00000214022,ENSG00000146112,ENSG00000198736,ENSG00000145337,ENSG00000144043,ENSG00000049541,ENSG00000196834,ENSG00000175283,ENSG00000104738,ENSG00000119318,ENSG00000172531,ENSG00000178691,ENSG00000129968,ENSG00000257390,ENSG00000153044,ENSG00000140284,ENSG00000137309,ENSG00000132321,ENSG00000006756,ENSG00000041357,ENSG00000125354,ENSG00000125870,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000152601,ENSG00000189306,ENSG00000104472,ENSG00000066583,ENSG00000092841,ENSG00000091127,ENSG00000213366,ENSG00000140319,ENSG00000182628,ENSG00000183726,ENSG00000177076,ENSG00000127951,ENSG00000137310,ENSG00000155660,ENSG00000101082,ENSG00000164576,ENSG00000197409,ENSG00000172667,ENSG00000150756,ENSG00000131873,ENSG00000173660,ENSG00000137312,ENSG00000196839,ENSG00000132388,ENSG00000143321,ENSG00000136104,ENSG00000089693,ENSG00000232838,ENSG00000155090,ENSG00000148218,ENSG00000242574,ENSG00000147168,ENSG00000134690,ENSG00000184575,ENSG00000177674,ENSG00000103489,ENSG00000011007,ENSG00000154518,ENSG00000028137,ENSG00000160753,ENSG00000178685,ENSG00000169223,ENSG00000132256,ENSG00000111481,ENSG00000147889,ENSG00000139926,ENSG00000140575,ENSG00000137193,ENSG00000160404,ENSG00000111450,ENSG00000155096,ENSG00000175104,ENSG00000078124,ENSG00000196642,ENSG00000110218,ENSG00000169554,ENSG00000127084,ENSG00000120280,ENSG00000113387,ENSG00000166794,ENSG00000114631,ENSG00000111859,ENSG00000147180,ENSG00000170485,ENSG00000130818 |
| GO:0070062 | extracellular exosome | 0.0000000 | 2144 | 739 | 145 | 0.1962111 | 0.0676306 | GO:CC | ENSG00000004468,ENSG00000150687,ENSG00000196126,ENSG00000092010,ENSG00000072110,ENSG00000108679,ENSG00000179218,ENSG00000159674,ENSG00000155657,ENSG00000097021,ENSG00000182054,ENSG00000019582,ENSG00000142669,ENSG00000117560,ENSG00000203747,ENSG00000143870,ENSG00000186469,ENSG00000069702,ENSG00000100911,ENSG00000205336,ENSG00000164111,ENSG00000177156,ENSG00000170315,ENSG00000125868,ENSG00000117632,ENSG00000167004,ENSG00000196924,ENSG00000117984,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000172331,ENSG00000172757,ENSG00000111885,ENSG00000134308,ENSG00000111640,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000103769,ENSG00000100380,ENSG00000108518,ENSG00000131171,ENSG00000005844,ENSG00000130592,ENSG00000116288,ENSG00000196230,ENSG00000134765,ENSG00000122121,ENSG00000075234,ENSG00000175793,ENSG00000103966,ENSG00000137563,ENSG00000204264,ENSG00000114978,ENSG00000187446,ENSG00000130402,ENSG00000170312,ENSG00000163359,ENSG00000117394,ENSG00000135069,ENSG00000242372,ENSG00000124299,ENSG00000065135,ENSG00000104687,ENSG00000213281,ENSG00000123131,ENSG00000041353,ENSG00000163041,ENSG00000044574,ENSG00000130741,ENSG00000072958,ENSG00000173786,ENSG00000166710,ENSG00000111229,ENSG00000104805,ENSG00000147065,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000107317,ENSG00000111348,ENSG00000021355,ENSG00000101444,ENSG00000074800,ENSG00000084623,ENSG00000105220,ENSG00000181467,ENSG00000071994,ENSG00000155368,ENSG00000100299,ENSG00000067560,ENSG00000213719,ENSG00000213064,ENSG00000134202,ENSG00000133026,ENSG00000174684,ENSG00000143727,ENSG00000006625,ENSG00000115339,ENSG00000115902,ENSG00000172270,ENSG00000148175,ENSG00000204592,ENSG00000083444,ENSG00000002549,ENSG00000130812,ENSG00000153310,ENSG00000178996,ENSG00000070831,ENSG00000079691,ENSG00000101079,ENSG00000171302,ENSG00000197043,ENSG00000132670,ENSG00000075624,ENSG00000075239,ENSG00000136824,ENSG00000165527,ENSG00000105612,ENSG00000127022,ENSG00000197956,ENSG00000121579,ENSG00000055163,ENSG00000132386,ENSG00000123338,ENSG00000126432,ENSG00000196834,ENSG00000172531,ENSG00000140284,ENSG00000041357,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000092841,ENSG00000213366,ENSG00000127951,ENSG00000197409,ENSG00000137312,ENSG00000132388,ENSG00000148218,ENSG00000169223,ENSG00000140575,ENSG00000113387,ENSG00000166794 |
| GO:0043229 | intracellular organelle | 0.0000000 | 12840 | 739 | 583 | 0.7889039 | 0.0454050 | GO:CC | ENSG00000172057,ENSG00000134824,ENSG00000100453,ENSG00000004468,ENSG00000150687,ENSG00000196169,ENSG00000148773,ENSG00000164308,ENSG00000179344,ENSG00000152217,ENSG00000156587,ENSG00000119922,ENSG00000138496,ENSG00000204267,ENSG00000113721,ENSG00000176083,ENSG00000196126,ENSG00000183688,ENSG00000229474,ENSG00000092010,ENSG00000248905,ENSG00000072110,ENSG00000129595,ENSG00000073861,ENSG00000163599,ENSG00000132530,ENSG00000117724,ENSG00000125347,ENSG00000157423,ENSG00000108679,ENSG00000100321,ENSG00000109956,ENSG00000179218,ENSG00000163492,ENSG00000115523,ENSG00000002834,ENSG00000126709,ENSG00000184357,ENSG00000135077,ENSG00000090857,ENSG00000165891,ENSG00000154451,ENSG00000162654,ENSG00000100427,ENSG00000080573,ENSG00000155657,ENSG00000163840,ENSG00000057704,ENSG00000097021,ENSG00000196735,ENSG00000182054,ENSG00000123485,ENSG00000231925,ENSG00000019582,ENSG00000142669,ENSG00000117560,ENSG00000144354,ENSG00000198513,ENSG00000072135,ENSG00000164649,ENSG00000159216,ENSG00000151502,ENSG00000160014,ENSG00000034510,ENSG00000130164,ENSG00000127124,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000100911,ENSG00000197928,ENSG00000130511,ENSG00000124191,ENSG00000198046,ENSG00000113368,ENSG00000101057,ENSG00000177156,ENSG00000163029,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000166503,ENSG00000156970,ENSG00000213512,ENSG00000125868,ENSG00000105639,ENSG00000125864,ENSG00000117632,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000175550,ENSG00000118193,ENSG00000112029,ENSG00000065911,ENSG00000117984,ENSG00000127947,ENSG00000157216,ENSG00000150093,ENSG00000136167,ENSG00000121039,ENSG00000167461,ENSG00000105409,ENSG00000123609,ENSG00000165512,ENSG00000173848,ENSG00000138160,ENSG00000077312,ENSG00000165617,ENSG00000125249,ENSG00000149328,ENSG00000111206,ENSG00000172757,ENSG00000138795,ENSG00000110090,ENSG00000102554,ENSG00000111885,ENSG00000179051,ENSG00000123179,ENSG00000112139,ENSG00000189430,ENSG00000099194,ENSG00000232810,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000126787,ENSG00000171202,ENSG00000176890,ENSG00000176293,ENSG00000133739,ENSG00000100749,ENSG00000108179,ENSG00000111640,ENSG00000118777,ENSG00000183734,ENSG00000172292,ENSG00000132646,ENSG00000103769,ENSG00000108518,ENSG00000117226,ENSG00000183741,ENSG00000131171,ENSG00000189319,ENSG00000005844,ENSG00000130592,ENSG00000103148,ENSG00000084092,ENSG00000167123,ENSG00000137474,ENSG00000116288,ENSG00000196230,ENSG00000134765,ENSG00000180644,ENSG00000111602,ENSG00000103202,ENSG00000213390,ENSG00000135114,ENSG00000134321,ENSG00000175793,ENSG00000169855,ENSG00000103966,ENSG00000124575,ENSG00000189420,ENSG00000023572,ENSG00000100918,ENSG00000152465,ENSG00000156463,ENSG00000143543,ENSG00000137563,ENSG00000138642,ENSG00000106392,ENSG00000204264,ENSG00000173821,ENSG00000143742,ENSG00000105011,ENSG00000157045,ENSG00000051341,ENSG00000131018,ENSG00000205413,ENSG00000196976,ENSG00000136274,ENSG00000077984,ENSG00000114978,ENSG00000187446,ENSG00000130402,ENSG00000188312,ENSG00000011426,ENSG00000170312,ENSG00000105887,ENSG00000110060,ENSG00000155846,ENSG00000136436,ENSG00000163359,ENSG00000185651,ENSG00000164830,ENSG00000117394,ENSG00000172116,ENSG00000131944,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000125462,ENSG00000165949,ENSG00000185304,ENSG00000152969,ENSG00000099840,ENSG00000092853,ENSG00000215305,ENSG00000055332,ENSG00000239713,ENSG00000242372,ENSG00000169230,ENSG00000153094,ENSG00000123416,ENSG00000152229,ENSG00000065135,ENSG00000213445,ENSG00000104687,ENSG00000213281,ENSG00000171451,ENSG00000164919,ENSG00000110080,ENSG00000123131,ENSG00000159200,ENSG00000122971,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000164211,ENSG00000041353,ENSG00000089127,ENSG00000152256,ENSG00000204472,ENSG00000171130,ENSG00000184007,ENSG00000089685,ENSG00000189159,ENSG00000121297,ENSG00000163041,ENSG00000044574,ENSG00000133315,ENSG00000124587,ENSG00000188612,ENSG00000171246,ENSG00000181938,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000233954,ENSG00000072958,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000111229,ENSG00000104805,ENSG00000179632,ENSG00000163545,ENSG00000152778,ENSG00000147065,ENSG00000166974,ENSG00000142556,ENSG00000166454,ENSG00000204899,ENSG00000129422,ENSG00000166197,ENSG00000204822,ENSG00000154001,ENSG00000126016,ENSG00000241258,ENSG00000206127,ENSG00000253626,ENSG00000073910,ENSG00000131931,ENSG00000171970,ENSG00000138071,ENSG00000100897,ENSG00000166598,ENSG00000131236,ENSG00000157985,ENSG00000107317,ENSG00000111348,ENSG00000132661,ENSG00000100342,ENSG00000225921,ENSG00000112031,ENSG00000118971,ENSG00000129534,ENSG00000084090,ENSG00000177150,ENSG00000021355,ENSG00000196954,ENSG00000177613,ENSG00000115155,ENSG00000093009,ENSG00000101444,ENSG00000185650,ENSG00000125871,ENSG00000111331,ENSG00000074800,ENSG00000143476,ENSG00000172803,ENSG00000122952,ENSG00000105220,ENSG00000143228,ENSG00000181467,ENSG00000158869,ENSG00000171222,ENSG00000196449,ENSG00000172164,ENSG00000053254,ENSG00000145649,ENSG00000136717,ENSG00000071994,ENSG00000155368,ENSG00000100299,ENSG00000134909,ENSG00000158006,ENSG00000163131,ENSG00000170881,ENSG00000100385,ENSG00000130005,ENSG00000125148,ENSG00000139921,ENSG00000131504,ENSG00000128039,ENSG00000134490,ENSG00000011485,ENSG00000067560,ENSG00000196436,ENSG00000132932,ENSG00000154027,ENSG00000213928,ENSG00000125944,ENSG00000127952,ENSG00000183172,ENSG00000114166,ENSG00000049449,ENSG00000189283,ENSG00000213719,ENSG00000165304,ENSG00000134202,ENSG00000172794,ENSG00000075340,ENSG00000133026,ENSG00000174684,ENSG00000113810,ENSG00000115520,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000144597,ENSG00000204642,ENSG00000115267,ENSG00000204256,ENSG00000087302,ENSG00000101474,ENSG00000151466,ENSG00000168961,ENSG00000115339,ENSG00000115902,ENSG00000122122,ENSG00000158882,ENSG00000180938,ENSG00000172270,ENSG00000122877,ENSG00000165283,ENSG00000173517,ENSG00000172795,ENSG00000148175,ENSG00000131747,ENSG00000171617,ENSG00000141736,ENSG00000132963,ENSG00000162702,ENSG00000204592,ENSG00000132182,ENSG00000132792,ENSG00000083444,ENSG00000103994,ENSG00000158321,ENSG00000237190,ENSG00000174371,ENSG00000116771,ENSG00000160877,ENSG00000002549,ENSG00000129625,ENSG00000213626,ENSG00000166881,ENSG00000167286,ENSG00000187608,ENSG00000021762,ENSG00000130812,ENSG00000198843,ENSG00000139579,ENSG00000103495,ENSG00000162676,ENSG00000068489,ENSG00000106462,ENSG00000042753,ENSG00000153310,ENSG00000178996,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000152253,ENSG00000079691,ENSG00000172936,ENSG00000112996,ENSG00000124920,ENSG00000170860,ENSG00000171169,ENSG00000151239,ENSG00000118705,ENSG00000164088,ENSG00000243660,ENSG00000128294,ENSG00000179583,ENSG00000171302,ENSG00000153790,ENSG00000178719,ENSG00000166035,ENSG00000141030,ENSG00000074071,ENSG00000147234,ENSG00000197142,ENSG00000197043,ENSG00000189266,ENSG00000066279,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000176542,ENSG00000128394,ENSG00000075239,ENSG00000176641,ENSG00000130348,ENSG00000109674,ENSG00000136824,ENSG00000079999,ENSG00000165527,ENSG00000117155,ENSG00000105612,ENSG00000162385,ENSG00000171954,ENSG00000127666,ENSG00000159111,ENSG00000139370,ENSG00000109084,ENSG00000223496,ENSG00000127022,ENSG00000197956,ENSG00000109805,ENSG00000026751,ENSG00000121579,ENSG00000138018,ENSG00000148908,ENSG00000196072,ENSG00000138617,ENSG00000184897,ENSG00000102931,ENSG00000125648,ENSG00000116670,ENSG00000184154,ENSG00000072571,ENSG00000055163,ENSG00000185880,ENSG00000184640,ENSG00000090520,ENSG00000132386,ENSG00000049239,ENSG00000127774,ENSG00000123338,ENSG00000010270,ENSG00000109536,ENSG00000140450,ENSG00000128272,ENSG00000134049,ENSG00000148337,ENSG00000124688,ENSG00000120709,ENSG00000142867,ENSG00000111335,ENSG00000114126,ENSG00000109390,ENSG00000143740,ENSG00000126432,ENSG00000124155,ENSG00000214022,ENSG00000146112,ENSG00000198736,ENSG00000145337,ENSG00000144043,ENSG00000049541,ENSG00000175283,ENSG00000104738,ENSG00000119318,ENSG00000172531,ENSG00000178691,ENSG00000129968,ENSG00000257390,ENSG00000153044,ENSG00000140284,ENSG00000137309,ENSG00000132321,ENSG00000006756,ENSG00000041357,ENSG00000125354,ENSG00000125870,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000152601,ENSG00000189306,ENSG00000104472,ENSG00000066583,ENSG00000092841,ENSG00000091127,ENSG00000213366,ENSG00000140319,ENSG00000182628,ENSG00000183726,ENSG00000177076,ENSG00000127951,ENSG00000137310,ENSG00000155660,ENSG00000101082,ENSG00000164576,ENSG00000197409,ENSG00000172667,ENSG00000150756,ENSG00000131873,ENSG00000173660,ENSG00000137312,ENSG00000196839,ENSG00000143321,ENSG00000136104,ENSG00000089693,ENSG00000232838,ENSG00000155090,ENSG00000148218,ENSG00000242574,ENSG00000147168,ENSG00000134690,ENSG00000184575,ENSG00000177674,ENSG00000103489,ENSG00000011007,ENSG00000154518,ENSG00000028137,ENSG00000160753,ENSG00000178685,ENSG00000169223,ENSG00000132256,ENSG00000111481,ENSG00000147889,ENSG00000139926,ENSG00000140575,ENSG00000137193,ENSG00000160404,ENSG00000111450,ENSG00000155096,ENSG00000175104,ENSG00000078124,ENSG00000196642,ENSG00000110218,ENSG00000169554,ENSG00000127084,ENSG00000120280,ENSG00000113387,ENSG00000166794,ENSG00000114631,ENSG00000111859,ENSG00000147180,ENSG00000170485,ENSG00000130818 |
| GO:0031410 | cytoplasmic vesicle | 0.0000000 | 2372 | 739 | 155 | 0.2097429 | 0.0653457 | GO:CC | ENSG00000172057,ENSG00000004468,ENSG00000179344,ENSG00000204267,ENSG00000113721,ENSG00000196126,ENSG00000072110,ENSG00000163599,ENSG00000108679,ENSG00000100321,ENSG00000179218,ENSG00000115523,ENSG00000135077,ENSG00000154451,ENSG00000162654,ENSG00000100427,ENSG00000163840,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000117560,ENSG00000151502,ENSG00000160014,ENSG00000130164,ENSG00000143870,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000117984,ENSG00000150093,ENSG00000167461,ENSG00000125249,ENSG00000179051,ENSG00000232810,ENSG00000117228,ENSG00000103769,ENSG00000117226,ENSG00000005844,ENSG00000137474,ENSG00000196230,ENSG00000134765,ENSG00000180644,ENSG00000103966,ENSG00000137563,ENSG00000077984,ENSG00000187446,ENSG00000130402,ENSG00000136436,ENSG00000117394,ENSG00000172116,ENSG00000070018,ENSG00000171603,ENSG00000215305,ENSG00000065135,ENSG00000213445,ENSG00000213281,ENSG00000123131,ENSG00000148400,ENSG00000157601,ENSG00000164211,ENSG00000041353,ENSG00000171130,ENSG00000184007,ENSG00000044574,ENSG00000171246,ENSG00000064666,ENSG00000072958,ENSG00000173786,ENSG00000166710,ENSG00000104805,ENSG00000126016,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000111348,ENSG00000021355,ENSG00000115155,ENSG00000101444,ENSG00000172803,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000136717,ENSG00000100299,ENSG00000134909,ENSG00000163131,ENSG00000100385,ENSG00000131504,ENSG00000067560,ENSG00000132932,ENSG00000172794,ENSG00000075340,ENSG00000185507,ENSG00000204642,ENSG00000115902,ENSG00000172270,ENSG00000148175,ENSG00000141736,ENSG00000204592,ENSG00000167286,ENSG00000130812,ENSG00000042753,ENSG00000153310,ENSG00000178996,ENSG00000070831,ENSG00000079691,ENSG00000172936,ENSG00000171302,ENSG00000147234,ENSG00000197043,ENSG00000113369,ENSG00000096968,ENSG00000165527,ENSG00000127666,ENSG00000139370,ENSG00000127022,ENSG00000132386,ENSG00000123338,ENSG00000010270,ENSG00000140450,ENSG00000134049,ENSG00000143740,ENSG00000126432,ENSG00000124155,ENSG00000144043,ENSG00000129968,ENSG00000140284,ENSG00000125354,ENSG00000139998,ENSG00000160255,ENSG00000140319,ENSG00000127951,ENSG00000155660,ENSG00000101082,ENSG00000137312,ENSG00000196839,ENSG00000148218,ENSG00000242574,ENSG00000147168,ENSG00000177674,ENSG00000028137,ENSG00000160753,ENSG00000169223,ENSG00000111481,ENSG00000140575,ENSG00000111450,ENSG00000175104,ENSG00000166794 |
| GO:0097708 | intracellular vesicle | 0.0000000 | 2375 | 739 | 155 | 0.2097429 | 0.0652632 | GO:CC | ENSG00000172057,ENSG00000004468,ENSG00000179344,ENSG00000204267,ENSG00000113721,ENSG00000196126,ENSG00000072110,ENSG00000163599,ENSG00000108679,ENSG00000100321,ENSG00000179218,ENSG00000115523,ENSG00000135077,ENSG00000154451,ENSG00000162654,ENSG00000100427,ENSG00000163840,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000117560,ENSG00000151502,ENSG00000160014,ENSG00000130164,ENSG00000143870,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000117984,ENSG00000150093,ENSG00000167461,ENSG00000125249,ENSG00000179051,ENSG00000232810,ENSG00000117228,ENSG00000103769,ENSG00000117226,ENSG00000005844,ENSG00000137474,ENSG00000196230,ENSG00000134765,ENSG00000180644,ENSG00000103966,ENSG00000137563,ENSG00000077984,ENSG00000187446,ENSG00000130402,ENSG00000136436,ENSG00000117394,ENSG00000172116,ENSG00000070018,ENSG00000171603,ENSG00000215305,ENSG00000065135,ENSG00000213445,ENSG00000213281,ENSG00000123131,ENSG00000148400,ENSG00000157601,ENSG00000164211,ENSG00000041353,ENSG00000171130,ENSG00000184007,ENSG00000044574,ENSG00000171246,ENSG00000064666,ENSG00000072958,ENSG00000173786,ENSG00000166710,ENSG00000104805,ENSG00000126016,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000111348,ENSG00000021355,ENSG00000115155,ENSG00000101444,ENSG00000172803,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000136717,ENSG00000100299,ENSG00000134909,ENSG00000163131,ENSG00000100385,ENSG00000131504,ENSG00000067560,ENSG00000132932,ENSG00000172794,ENSG00000075340,ENSG00000185507,ENSG00000204642,ENSG00000115902,ENSG00000172270,ENSG00000148175,ENSG00000141736,ENSG00000204592,ENSG00000167286,ENSG00000130812,ENSG00000042753,ENSG00000153310,ENSG00000178996,ENSG00000070831,ENSG00000079691,ENSG00000172936,ENSG00000171302,ENSG00000147234,ENSG00000197043,ENSG00000113369,ENSG00000096968,ENSG00000165527,ENSG00000127666,ENSG00000139370,ENSG00000127022,ENSG00000132386,ENSG00000123338,ENSG00000010270,ENSG00000140450,ENSG00000134049,ENSG00000143740,ENSG00000126432,ENSG00000124155,ENSG00000144043,ENSG00000129968,ENSG00000140284,ENSG00000125354,ENSG00000139998,ENSG00000160255,ENSG00000140319,ENSG00000127951,ENSG00000155660,ENSG00000101082,ENSG00000137312,ENSG00000196839,ENSG00000148218,ENSG00000242574,ENSG00000147168,ENSG00000177674,ENSG00000028137,ENSG00000160753,ENSG00000169223,ENSG00000111481,ENSG00000140575,ENSG00000111450,ENSG00000175104,ENSG00000166794 |
| GO:0042470 | melanosome | 0.0000000 | 104 | 739 | 22 | 0.0297700 | 0.2115385 | GO:CC | ENSG00000100321,ENSG00000143870,ENSG00000167004,ENSG00000117984,ENSG00000150093,ENSG00000137474,ENSG00000137563,ENSG00000117394,ENSG00000041353,ENSG00000044574,ENSG00000173786,ENSG00000166598,ENSG00000101444,ENSG00000115902,ENSG00000172270,ENSG00000148175,ENSG00000197043,ENSG00000127022,ENSG00000132386,ENSG00000155660,ENSG00000137312,ENSG00000166794 |
| GO:0048770 | pigment granule | 0.0000000 | 104 | 739 | 22 | 0.0297700 | 0.2115385 | GO:CC | ENSG00000100321,ENSG00000143870,ENSG00000167004,ENSG00000117984,ENSG00000150093,ENSG00000137474,ENSG00000137563,ENSG00000117394,ENSG00000041353,ENSG00000044574,ENSG00000173786,ENSG00000166598,ENSG00000101444,ENSG00000115902,ENSG00000172270,ENSG00000148175,ENSG00000197043,ENSG00000127022,ENSG00000132386,ENSG00000155660,ENSG00000137312,ENSG00000166794 |
| GO:0009897 | external side of plasma membrane | 0.0000000 | 405 | 739 | 46 | 0.0622463 | 0.1135802 | GO:CC | ENSG00000179344,ENSG00000196126,ENSG00000163599,ENSG00000179218,ENSG00000089692,ENSG00000181036,ENSG00000019582,ENSG00000117560,ENSG00000203747,ENSG00000130164,ENSG00000069702,ENSG00000091129,ENSG00000164111,ENSG00000160654,ENSG00000186470,ENSG00000150093,ENSG00000096996,ENSG00000211698,ENSG00000232810,ENSG00000134539,ENSG00000118777,ENSG00000134352,ENSG00000153563,ENSG00000122223,ENSG00000104687,ENSG00000166710,ENSG00000163823,ENSG00000126016,ENSG00000110448,ENSG00000158869,ENSG00000100299,ENSG00000013725,ENSG00000100385,ENSG00000149294,ENSG00000204642,ENSG00000204592,ENSG00000167286,ENSG00000157873,ENSG00000168329,ENSG00000160255,ENSG00000131019,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000147168,ENSG00000081985 |
| GO:0012505 | endomembrane system | 0.0000000 | 4539 | 739 | 251 | 0.3396482 | 0.0552985 | GO:CC | ENSG00000172057,ENSG00000134824,ENSG00000004468,ENSG00000150687,ENSG00000164308,ENSG00000179344,ENSG00000119922,ENSG00000204267,ENSG00000113721,ENSG00000196126,ENSG00000248905,ENSG00000072110,ENSG00000163599,ENSG00000117724,ENSG00000108679,ENSG00000100321,ENSG00000109956,ENSG00000179218,ENSG00000135077,ENSG00000154451,ENSG00000162654,ENSG00000100427,ENSG00000080573,ENSG00000163840,ENSG00000057704,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000198513,ENSG00000151502,ENSG00000160014,ENSG00000130164,ENSG00000143870,ENSG00000113368,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000105639,ENSG00000142089,ENSG00000169252,ENSG00000167004,ENSG00000146674,ENSG00000117984,ENSG00000150093,ENSG00000121039,ENSG00000167461,ENSG00000105409,ENSG00000125249,ENSG00000102554,ENSG00000111885,ENSG00000179051,ENSG00000123179,ENSG00000112139,ENSG00000099194,ENSG00000232810,ENSG00000117228,ENSG00000100749,ENSG00000111640,ENSG00000172292,ENSG00000103769,ENSG00000128335,ENSG00000117226,ENSG00000005844,ENSG00000167123,ENSG00000116288,ENSG00000196230,ENSG00000134765,ENSG00000103512,ENSG00000180644,ENSG00000134321,ENSG00000103966,ENSG00000152465,ENSG00000137563,ENSG00000106392,ENSG00000143742,ENSG00000131018,ENSG00000077984,ENSG00000187446,ENSG00000130402,ENSG00000170312,ENSG00000163359,ENSG00000117394,ENSG00000172116,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000165949,ENSG00000185304,ENSG00000092853,ENSG00000215305,ENSG00000153094,ENSG00000065135,ENSG00000213445,ENSG00000213281,ENSG00000171451,ENSG00000110080,ENSG00000123131,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000041353,ENSG00000089127,ENSG00000171130,ENSG00000184007,ENSG00000189159,ENSG00000044574,ENSG00000171246,ENSG00000116030,ENSG00000064666,ENSG00000072958,ENSG00000132274,ENSG00000166710,ENSG00000104805,ENSG00000129422,ENSG00000241258,ENSG00000206127,ENSG00000253626,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000107317,ENSG00000132661,ENSG00000100342,ENSG00000118971,ENSG00000021355,ENSG00000196954,ENSG00000115155,ENSG00000143476,ENSG00000172803,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000136717,ENSG00000155368,ENSG00000100299,ENSG00000134909,ENSG00000158006,ENSG00000163131,ENSG00000170881,ENSG00000100385,ENSG00000139921,ENSG00000131504,ENSG00000128039,ENSG00000134490,ENSG00000067560,ENSG00000132932,ENSG00000125944,ENSG00000049449,ENSG00000213719,ENSG00000172794,ENSG00000174684,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000101474,ENSG00000115339,ENSG00000172270,ENSG00000148175,ENSG00000141736,ENSG00000132963,ENSG00000204592,ENSG00000132182,ENSG00000083444,ENSG00000002549,ENSG00000129625,ENSG00000166881,ENSG00000021762,ENSG00000130812,ENSG00000198843,ENSG00000042753,ENSG00000153310,ENSG00000178996,ENSG00000104765,ENSG00000070831,ENSG00000079691,ENSG00000172936,ENSG00000124920,ENSG00000118705,ENSG00000128294,ENSG00000171302,ENSG00000178719,ENSG00000166035,ENSG00000147234,ENSG00000197142,ENSG00000197043,ENSG00000189266,ENSG00000113369,ENSG00000096968,ENSG00000079999,ENSG00000165527,ENSG00000171954,ENSG00000127666,ENSG00000139370,ENSG00000109084,ENSG00000127022,ENSG00000197956,ENSG00000026751,ENSG00000138018,ENSG00000138617,ENSG00000184154,ENSG00000090520,ENSG00000049239,ENSG00000127774,ENSG00000123338,ENSG00000010270,ENSG00000140450,ENSG00000134049,ENSG00000124688,ENSG00000143740,ENSG00000124155,ENSG00000145337,ENSG00000144043,ENSG00000175283,ENSG00000129968,ENSG00000140284,ENSG00000006756,ENSG00000125354,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000213366,ENSG00000140319,ENSG00000183726,ENSG00000177076,ENSG00000127951,ENSG00000155660,ENSG00000101082,ENSG00000131873,ENSG00000137312,ENSG00000148218,ENSG00000242574,ENSG00000147168,ENSG00000184575,ENSG00000177674,ENSG00000103489,ENSG00000028137,ENSG00000160753,ENSG00000178685,ENSG00000169223,ENSG00000132256,ENSG00000111481,ENSG00000140575,ENSG00000160404,ENSG00000111450,ENSG00000175104,ENSG00000078124,ENSG00000110218,ENSG00000127084,ENSG00000166794,ENSG00000114631,ENSG00000111859 |
| GO:0043231 | intracellular membrane-bounded organelle | 0.0000001 | 11067 | 739 | 511 | 0.6914750 | 0.0461733 | GO:CC | ENSG00000172057,ENSG00000134824,ENSG00000100453,ENSG00000004468,ENSG00000150687,ENSG00000148773,ENSG00000164308,ENSG00000179344,ENSG00000152217,ENSG00000156587,ENSG00000119922,ENSG00000138496,ENSG00000204267,ENSG00000113721,ENSG00000176083,ENSG00000196126,ENSG00000229474,ENSG00000092010,ENSG00000248905,ENSG00000073861,ENSG00000163599,ENSG00000132530,ENSG00000117724,ENSG00000125347,ENSG00000100321,ENSG00000109956,ENSG00000179218,ENSG00000115523,ENSG00000126709,ENSG00000184357,ENSG00000135077,ENSG00000090857,ENSG00000165891,ENSG00000154451,ENSG00000162654,ENSG00000100427,ENSG00000080573,ENSG00000155657,ENSG00000163840,ENSG00000057704,ENSG00000097021,ENSG00000196735,ENSG00000182054,ENSG00000123485,ENSG00000231925,ENSG00000019582,ENSG00000142669,ENSG00000117560,ENSG00000144354,ENSG00000198513,ENSG00000072135,ENSG00000164649,ENSG00000159216,ENSG00000160014,ENSG00000130164,ENSG00000127124,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000100911,ENSG00000197928,ENSG00000130511,ENSG00000124191,ENSG00000198046,ENSG00000113368,ENSG00000101057,ENSG00000177156,ENSG00000163029,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000166503,ENSG00000156970,ENSG00000142089,ENSG00000169252,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000175550,ENSG00000118193,ENSG00000112029,ENSG00000065911,ENSG00000117984,ENSG00000127947,ENSG00000157216,ENSG00000121039,ENSG00000167461,ENSG00000105409,ENSG00000123609,ENSG00000165512,ENSG00000173848,ENSG00000138160,ENSG00000077312,ENSG00000165617,ENSG00000149328,ENSG00000111206,ENSG00000172757,ENSG00000138795,ENSG00000110090,ENSG00000102554,ENSG00000111885,ENSG00000179051,ENSG00000123179,ENSG00000112139,ENSG00000189430,ENSG00000099194,ENSG00000117228,ENSG00000134308,ENSG00000126787,ENSG00000171202,ENSG00000176890,ENSG00000176293,ENSG00000100749,ENSG00000108179,ENSG00000111640,ENSG00000118777,ENSG00000183734,ENSG00000172292,ENSG00000132646,ENSG00000103769,ENSG00000108518,ENSG00000117226,ENSG00000183741,ENSG00000131171,ENSG00000189319,ENSG00000103148,ENSG00000084092,ENSG00000167123,ENSG00000137474,ENSG00000116288,ENSG00000196230,ENSG00000180644,ENSG00000111602,ENSG00000103202,ENSG00000213390,ENSG00000135114,ENSG00000134321,ENSG00000175793,ENSG00000169855,ENSG00000103966,ENSG00000124575,ENSG00000189420,ENSG00000023572,ENSG00000100918,ENSG00000152465,ENSG00000156463,ENSG00000143543,ENSG00000137563,ENSG00000138642,ENSG00000106392,ENSG00000204264,ENSG00000173821,ENSG00000143742,ENSG00000105011,ENSG00000157045,ENSG00000051341,ENSG00000131018,ENSG00000205413,ENSG00000196976,ENSG00000136274,ENSG00000077984,ENSG00000114978,ENSG00000187446,ENSG00000130402,ENSG00000188312,ENSG00000011426,ENSG00000170312,ENSG00000105887,ENSG00000110060,ENSG00000155846,ENSG00000136436,ENSG00000163359,ENSG00000185651,ENSG00000164830,ENSG00000117394,ENSG00000131944,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000125462,ENSG00000165949,ENSG00000185304,ENSG00000099840,ENSG00000092853,ENSG00000215305,ENSG00000055332,ENSG00000239713,ENSG00000242372,ENSG00000169230,ENSG00000153094,ENSG00000065135,ENSG00000213445,ENSG00000104687,ENSG00000213281,ENSG00000171451,ENSG00000164919,ENSG00000110080,ENSG00000123131,ENSG00000159200,ENSG00000122971,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000041353,ENSG00000089127,ENSG00000152256,ENSG00000204472,ENSG00000184007,ENSG00000089685,ENSG00000189159,ENSG00000121297,ENSG00000163041,ENSG00000044574,ENSG00000133315,ENSG00000124587,ENSG00000188612,ENSG00000181938,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000118263,ENSG00000233954,ENSG00000072958,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000111229,ENSG00000104805,ENSG00000179632,ENSG00000163545,ENSG00000147065,ENSG00000142556,ENSG00000166454,ENSG00000129422,ENSG00000166197,ENSG00000204822,ENSG00000154001,ENSG00000126016,ENSG00000241258,ENSG00000206127,ENSG00000253626,ENSG00000131931,ENSG00000171970,ENSG00000138071,ENSG00000100897,ENSG00000166598,ENSG00000131236,ENSG00000157985,ENSG00000107317,ENSG00000132661,ENSG00000100342,ENSG00000225921,ENSG00000112031,ENSG00000118971,ENSG00000129534,ENSG00000084090,ENSG00000177150,ENSG00000196954,ENSG00000177613,ENSG00000115155,ENSG00000093009,ENSG00000101444,ENSG00000185650,ENSG00000125871,ENSG00000111331,ENSG00000074800,ENSG00000143476,ENSG00000122952,ENSG00000105220,ENSG00000143228,ENSG00000171222,ENSG00000196449,ENSG00000053254,ENSG00000145649,ENSG00000136717,ENSG00000071994,ENSG00000155368,ENSG00000100299,ENSG00000134909,ENSG00000158006,ENSG00000163131,ENSG00000170881,ENSG00000130005,ENSG00000125148,ENSG00000139921,ENSG00000131504,ENSG00000128039,ENSG00000134490,ENSG00000011485,ENSG00000067560,ENSG00000196436,ENSG00000132932,ENSG00000213928,ENSG00000125944,ENSG00000127952,ENSG00000183172,ENSG00000114166,ENSG00000049449,ENSG00000189283,ENSG00000213719,ENSG00000165304,ENSG00000134202,ENSG00000172794,ENSG00000133026,ENSG00000174684,ENSG00000113810,ENSG00000115520,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000144597,ENSG00000204642,ENSG00000115267,ENSG00000204256,ENSG00000087302,ENSG00000101474,ENSG00000168961,ENSG00000115339,ENSG00000122122,ENSG00000158882,ENSG00000180938,ENSG00000172270,ENSG00000122877,ENSG00000165283,ENSG00000172795,ENSG00000148175,ENSG00000131747,ENSG00000171617,ENSG00000141736,ENSG00000132963,ENSG00000162702,ENSG00000204592,ENSG00000132182,ENSG00000132792,ENSG00000083444,ENSG00000103994,ENSG00000158321,ENSG00000237190,ENSG00000174371,ENSG00000116771,ENSG00000160877,ENSG00000002549,ENSG00000129625,ENSG00000213626,ENSG00000166881,ENSG00000187608,ENSG00000021762,ENSG00000198843,ENSG00000139579,ENSG00000103495,ENSG00000162676,ENSG00000068489,ENSG00000106462,ENSG00000042753,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000152253,ENSG00000079691,ENSG00000172936,ENSG00000112996,ENSG00000124920,ENSG00000170860,ENSG00000171169,ENSG00000118705,ENSG00000164088,ENSG00000243660,ENSG00000128294,ENSG00000179583,ENSG00000171302,ENSG00000178719,ENSG00000166035,ENSG00000141030,ENSG00000074071,ENSG00000197142,ENSG00000197043,ENSG00000189266,ENSG00000066279,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000176542,ENSG00000128394,ENSG00000075239,ENSG00000176641,ENSG00000130348,ENSG00000109674,ENSG00000136824,ENSG00000079999,ENSG00000165527,ENSG00000117155,ENSG00000105612,ENSG00000162385,ENSG00000171954,ENSG00000127666,ENSG00000159111,ENSG00000139370,ENSG00000109084,ENSG00000223496,ENSG00000127022,ENSG00000197956,ENSG00000109805,ENSG00000026751,ENSG00000121579,ENSG00000138018,ENSG00000148908,ENSG00000196072,ENSG00000138617,ENSG00000184897,ENSG00000102931,ENSG00000125648,ENSG00000116670,ENSG00000184154,ENSG00000055163,ENSG00000185880,ENSG00000090520,ENSG00000049239,ENSG00000127774,ENSG00000010270,ENSG00000109536,ENSG00000140450,ENSG00000128272,ENSG00000134049,ENSG00000148337,ENSG00000124688,ENSG00000120709,ENSG00000142867,ENSG00000111335,ENSG00000114126,ENSG00000109390,ENSG00000126432,ENSG00000124155,ENSG00000214022,ENSG00000198736,ENSG00000145337,ENSG00000144043,ENSG00000049541,ENSG00000175283,ENSG00000104738,ENSG00000119318,ENSG00000172531,ENSG00000178691,ENSG00000257390,ENSG00000153044,ENSG00000140284,ENSG00000137309,ENSG00000006756,ENSG00000041357,ENSG00000125870,ENSG00000254087,ENSG00000152601,ENSG00000189306,ENSG00000104472,ENSG00000066583,ENSG00000091127,ENSG00000213366,ENSG00000140319,ENSG00000183726,ENSG00000177076,ENSG00000137310,ENSG00000155660,ENSG00000101082,ENSG00000164576,ENSG00000197409,ENSG00000172667,ENSG00000150756,ENSG00000131873,ENSG00000173660,ENSG00000137312,ENSG00000196839,ENSG00000143321,ENSG00000136104,ENSG00000089693,ENSG00000232838,ENSG00000155090,ENSG00000148218,ENSG00000242574,ENSG00000134690,ENSG00000184575,ENSG00000177674,ENSG00000103489,ENSG00000011007,ENSG00000154518,ENSG00000028137,ENSG00000160753,ENSG00000178685,ENSG00000169223,ENSG00000132256,ENSG00000111481,ENSG00000147889,ENSG00000140575,ENSG00000137193,ENSG00000160404,ENSG00000111450,ENSG00000155096,ENSG00000175104,ENSG00000078124,ENSG00000196642,ENSG00000110218,ENSG00000169554,ENSG00000127084,ENSG00000120280,ENSG00000113387,ENSG00000166794,ENSG00000114631,ENSG00000111859,ENSG00000147180,ENSG00000170485,ENSG00000130818 |
| GO:0005925 | focal adhesion | 0.0000002 | 410 | 739 | 43 | 0.0581867 | 0.1048780 | GO:CC | ENSG00000113721,ENSG00000072110,ENSG00000179218,ENSG00000002834,ENSG00000164111,ENSG00000167004,ENSG00000196924,ENSG00000127947,ENSG00000150093,ENSG00000136167,ENSG00000172757,ENSG00000134308,ENSG00000139626,ENSG00000108518,ENSG00000073008,ENSG00000187446,ENSG00000130402,ENSG00000044574,ENSG00000064666,ENSG00000166710,ENSG00000111229,ENSG00000147065,ENSG00000166974,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000172164,ENSG00000067560,ENSG00000172270,ENSG00000173517,ENSG00000002549,ENSG00000070831,ENSG00000151239,ENSG00000197043,ENSG00000075624,ENSG00000096968,ENSG00000165527,ENSG00000137309,ENSG00000160255,ENSG00000137312,ENSG00000140575,ENSG00000166794,ENSG00000111859 |
| GO:0009986 | cell surface | 0.0000003 | 918 | 739 | 73 | 0.0987821 | 0.0795207 | GO:CC | ENSG00000004468,ENSG00000179344,ENSG00000113721,ENSG00000196126,ENSG00000156886,ENSG00000163599,ENSG00000179218,ENSG00000135077,ENSG00000089692,ENSG00000181036,ENSG00000019582,ENSG00000117560,ENSG00000203747,ENSG00000130164,ENSG00000069702,ENSG00000091129,ENSG00000164111,ENSG00000223865,ENSG00000231389,ENSG00000160654,ENSG00000167004,ENSG00000186470,ENSG00000150093,ENSG00000096996,ENSG00000211698,ENSG00000232810,ENSG00000134539,ENSG00000118777,ENSG00000134352,ENSG00000139626,ENSG00000153563,ENSG00000005844,ENSG00000073008,ENSG00000169855,ENSG00000122223,ENSG00000117394,ENSG00000172116,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000104687,ENSG00000148400,ENSG00000044574,ENSG00000166710,ENSG00000163823,ENSG00000147065,ENSG00000126016,ENSG00000110448,ENSG00000074800,ENSG00000158869,ENSG00000100299,ENSG00000013725,ENSG00000100385,ENSG00000149294,ENSG00000204642,ENSG00000101474,ENSG00000115902,ENSG00000204592,ENSG00000167286,ENSG00000157873,ENSG00000111863,ENSG00000179583,ENSG00000168329,ENSG00000072571,ENSG00000160255,ENSG00000155660,ENSG00000131019,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000147168,ENSG00000169223,ENSG00000081985 |
| GO:0030055 | cell-substrate junction | 0.0000004 | 417 | 739 | 43 | 0.0581867 | 0.1031175 | GO:CC | ENSG00000113721,ENSG00000072110,ENSG00000179218,ENSG00000002834,ENSG00000164111,ENSG00000167004,ENSG00000196924,ENSG00000127947,ENSG00000150093,ENSG00000136167,ENSG00000172757,ENSG00000134308,ENSG00000139626,ENSG00000108518,ENSG00000073008,ENSG00000187446,ENSG00000130402,ENSG00000044574,ENSG00000064666,ENSG00000166710,ENSG00000111229,ENSG00000147065,ENSG00000166974,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000172164,ENSG00000067560,ENSG00000172270,ENSG00000173517,ENSG00000002549,ENSG00000070831,ENSG00000151239,ENSG00000197043,ENSG00000075624,ENSG00000096968,ENSG00000165527,ENSG00000137309,ENSG00000160255,ENSG00000137312,ENSG00000140575,ENSG00000166794,ENSG00000111859 |
| GO:0042611 | MHC protein complex | 0.0000004 | 24 | 739 | 10 | 0.0135318 | 0.4166667 | GO:CC | ENSG00000179344,ENSG00000196126,ENSG00000196735,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000166710,ENSG00000204642,ENSG00000204592,ENSG00000242574 |
| GO:0071556 | integral component of lumenal side of endoplasmic reticulum membrane | 0.0000006 | 25 | 739 | 10 | 0.0135318 | 0.4000000 | GO:CC | ENSG00000196126,ENSG00000179218,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000204642,ENSG00000204592,ENSG00000127022 |
| GO:0098553 | lumenal side of endoplasmic reticulum membrane | 0.0000006 | 25 | 739 | 10 | 0.0135318 | 0.4000000 | GO:CC | ENSG00000196126,ENSG00000179218,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000204642,ENSG00000204592,ENSG00000127022 |
| GO:0098576 | lumenal side of membrane | 0.0000007 | 32 | 739 | 11 | 0.0148850 | 0.3437500 | GO:CC | ENSG00000196126,ENSG00000179218,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000104805,ENSG00000204642,ENSG00000204592,ENSG00000127022 |
| GO:0030496 | midbody | 0.0000020 | 183 | 739 | 25 | 0.0338295 | 0.1366120 | GO:CC | ENSG00000117724,ENSG00000118193,ENSG00000167461,ENSG00000125249,ENSG00000179051,ENSG00000138180,ENSG00000143543,ENSG00000011426,ENSG00000170312,ENSG00000117394,ENSG00000065135,ENSG00000089685,ENSG00000044574,ENSG00000166598,ENSG00000067560,ENSG00000133026,ENSG00000002549,ENSG00000070831,ENSG00000066279,ENSG00000079999,ENSG00000165527,ENSG00000102931,ENSG00000125354,ENSG00000134690,ENSG00000140575 |
| GO:0098805 | whole membrane | 0.0000048 | 1694 | 739 | 109 | 0.1474966 | 0.0643447 | GO:CC | ENSG00000172057,ENSG00000004468,ENSG00000204267,ENSG00000142634,ENSG00000196126,ENSG00000100321,ENSG00000179218,ENSG00000100427,ENSG00000163840,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000117560,ENSG00000160014,ENSG00000130164,ENSG00000205336,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000117984,ENSG00000150093,ENSG00000167461,ENSG00000125249,ENSG00000110090,ENSG00000179051,ENSG00000232810,ENSG00000118777,ENSG00000153563,ENSG00000103769,ENSG00000005844,ENSG00000103148,ENSG00000137474,ENSG00000116288,ENSG00000196230,ENSG00000134765,ENSG00000134321,ENSG00000103966,ENSG00000131018,ENSG00000136436,ENSG00000117394,ENSG00000172116,ENSG00000070018,ENSG00000171603,ENSG00000165949,ENSG00000215305,ENSG00000153094,ENSG00000123416,ENSG00000065135,ENSG00000213281,ENSG00000041353,ENSG00000171130,ENSG00000124587,ENSG00000072958,ENSG00000173786,ENSG00000166710,ENSG00000084090,ENSG00000115155,ENSG00000181467,ENSG00000158869,ENSG00000134909,ENSG00000131504,ENSG00000067560,ENSG00000172794,ENSG00000075340,ENSG00000185507,ENSG00000204642,ENSG00000158882,ENSG00000172270,ENSG00000165283,ENSG00000148175,ENSG00000141736,ENSG00000204592,ENSG00000167286,ENSG00000111863,ENSG00000042753,ENSG00000178996,ENSG00000104765,ENSG00000172936,ENSG00000118705,ENSG00000147234,ENSG00000197142,ENSG00000197043,ENSG00000096968,ENSG00000176641,ENSG00000165527,ENSG00000127666,ENSG00000139370,ENSG00000196072,ENSG00000123338,ENSG00000010270,ENSG00000142867,ENSG00000143740,ENSG00000129968,ENSG00000140284,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000101082,ENSG00000137312,ENSG00000242574,ENSG00000154518,ENSG00000028137,ENSG00000111481,ENSG00000140575,ENSG00000175104 |
| GO:0031090 | organelle membrane | 0.0000092 | 3531 | 739 | 193 | 0.2611637 | 0.0546587 | GO:CC | ENSG00000172057,ENSG00000134824,ENSG00000004468,ENSG00000164308,ENSG00000204267,ENSG00000196126,ENSG00000248905,ENSG00000100321,ENSG00000109956,ENSG00000179218,ENSG00000126709,ENSG00000154451,ENSG00000162654,ENSG00000163840,ENSG00000057704,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000198513,ENSG00000160014,ENSG00000130164,ENSG00000143870,ENSG00000113368,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000117984,ENSG00000121039,ENSG00000167461,ENSG00000105409,ENSG00000125249,ENSG00000110090,ENSG00000111885,ENSG00000179051,ENSG00000123179,ENSG00000099194,ENSG00000117228,ENSG00000171202,ENSG00000176890,ENSG00000108179,ENSG00000111640,ENSG00000118777,ENSG00000172292,ENSG00000103769,ENSG00000128335,ENSG00000117226,ENSG00000005844,ENSG00000103148,ENSG00000084092,ENSG00000137474,ENSG00000134765,ENSG00000103512,ENSG00000103202,ENSG00000134321,ENSG00000169855,ENSG00000103966,ENSG00000106392,ENSG00000143742,ENSG00000131018,ENSG00000187446,ENSG00000170312,ENSG00000136436,ENSG00000117394,ENSG00000172116,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000165949,ENSG00000215305,ENSG00000153094,ENSG00000065135,ENSG00000213281,ENSG00000171451,ENSG00000164919,ENSG00000110080,ENSG00000148400,ENSG00000157601,ENSG00000041353,ENSG00000171130,ENSG00000189159,ENSG00000044574,ENSG00000124587,ENSG00000116030,ENSG00000233954,ENSG00000072958,ENSG00000173786,ENSG00000166710,ENSG00000104805,ENSG00000204822,ENSG00000206127,ENSG00000253626,ENSG00000166598,ENSG00000107317,ENSG00000118971,ENSG00000084090,ENSG00000196954,ENSG00000115155,ENSG00000143476,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000134909,ENSG00000158006,ENSG00000170881,ENSG00000139921,ENSG00000131504,ENSG00000128039,ENSG00000067560,ENSG00000183172,ENSG00000213719,ENSG00000172794,ENSG00000174684,ENSG00000115520,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000115339,ENSG00000158882,ENSG00000172270,ENSG00000165283,ENSG00000148175,ENSG00000141736,ENSG00000132963,ENSG00000204592,ENSG00000132182,ENSG00000083444,ENSG00000166881,ENSG00000167286,ENSG00000021762,ENSG00000198843,ENSG00000042753,ENSG00000178996,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000112996,ENSG00000124920,ENSG00000118705,ENSG00000128294,ENSG00000171302,ENSG00000074071,ENSG00000147234,ENSG00000197142,ENSG00000197043,ENSG00000176641,ENSG00000165527,ENSG00000171954,ENSG00000127666,ENSG00000159111,ENSG00000139370,ENSG00000109084,ENSG00000127022,ENSG00000138018,ENSG00000196072,ENSG00000138617,ENSG00000125648,ENSG00000127774,ENSG00000123338,ENSG00000010270,ENSG00000134049,ENSG00000124688,ENSG00000109390,ENSG00000143740,ENSG00000124155,ENSG00000145337,ENSG00000144043,ENSG00000175283,ENSG00000129968,ENSG00000140284,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000177076,ENSG00000101082,ENSG00000150756,ENSG00000131873,ENSG00000173660,ENSG00000137312,ENSG00000242574,ENSG00000177674,ENSG00000103489,ENSG00000154518,ENSG00000028137,ENSG00000169223,ENSG00000111481,ENSG00000140575,ENSG00000175104,ENSG00000078124,ENSG00000110218 |
| GO:0098588 | bounding membrane of organelle | 0.0000092 | 2092 | 739 | 127 | 0.1718539 | 0.0607075 | GO:CC | ENSG00000172057,ENSG00000004468,ENSG00000204267,ENSG00000196126,ENSG00000100321,ENSG00000109956,ENSG00000179218,ENSG00000154451,ENSG00000162654,ENSG00000163840,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000198513,ENSG00000160014,ENSG00000130164,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000117984,ENSG00000167461,ENSG00000125249,ENSG00000110090,ENSG00000111885,ENSG00000179051,ENSG00000117228,ENSG00000103769,ENSG00000117226,ENSG00000005844,ENSG00000103148,ENSG00000137474,ENSG00000134765,ENSG00000134321,ENSG00000169855,ENSG00000103966,ENSG00000106392,ENSG00000143742,ENSG00000131018,ENSG00000187446,ENSG00000136436,ENSG00000117394,ENSG00000172116,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000165949,ENSG00000215305,ENSG00000153094,ENSG00000065135,ENSG00000213281,ENSG00000171451,ENSG00000110080,ENSG00000148400,ENSG00000041353,ENSG00000171130,ENSG00000124587,ENSG00000072958,ENSG00000173786,ENSG00000166710,ENSG00000104805,ENSG00000206127,ENSG00000084090,ENSG00000115155,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000134909,ENSG00000131504,ENSG00000067560,ENSG00000172794,ENSG00000174684,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000115339,ENSG00000158882,ENSG00000172270,ENSG00000148175,ENSG00000141736,ENSG00000204592,ENSG00000083444,ENSG00000167286,ENSG00000042753,ENSG00000178996,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000118705,ENSG00000128294,ENSG00000171302,ENSG00000147234,ENSG00000197142,ENSG00000197043,ENSG00000176641,ENSG00000165527,ENSG00000127666,ENSG00000139370,ENSG00000109084,ENSG00000196072,ENSG00000127774,ENSG00000123338,ENSG00000010270,ENSG00000134049,ENSG00000143740,ENSG00000144043,ENSG00000129968,ENSG00000140284,ENSG00000139998,ENSG00000160255,ENSG00000177076,ENSG00000101082,ENSG00000131873,ENSG00000137312,ENSG00000242574,ENSG00000177674,ENSG00000103489,ENSG00000154518,ENSG00000028137,ENSG00000169223,ENSG00000111481,ENSG00000140575,ENSG00000175104,ENSG00000078124 |
| GO:0005829 | cytosol | 0.0000105 | 5154 | 739 | 263 | 0.3558863 | 0.0510283 | GO:CC | ENSG00000100453,ENSG00000152217,ENSG00000156587,ENSG00000119922,ENSG00000138496,ENSG00000198826,ENSG00000092010,ENSG00000072110,ENSG00000073605,ENSG00000132530,ENSG00000117724,ENSG00000125347,ENSG00000179218,ENSG00000147459,ENSG00000162654,ENSG00000134184,ENSG00000155657,ENSG00000163840,ENSG00000097021,ENSG00000182054,ENSG00000144354,ENSG00000072135,ENSG00000164649,ENSG00000151502,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000155629,ENSG00000100911,ENSG00000164111,ENSG00000177156,ENSG00000170315,ENSG00000166503,ENSG00000156970,ENSG00000171848,ENSG00000105639,ENSG00000117632,ENSG00000160654,ENSG00000196924,ENSG00000137265,ENSG00000118193,ENSG00000112029,ENSG00000127947,ENSG00000136167,ENSG00000167461,ENSG00000123609,ENSG00000173848,ENSG00000138160,ENSG00000165617,ENSG00000172331,ENSG00000125249,ENSG00000133321,ENSG00000172757,ENSG00000111885,ENSG00000179051,ENSG00000117228,ENSG00000134308,ENSG00000126787,ENSG00000176890,ENSG00000100749,ENSG00000111640,ENSG00000167914,ENSG00000103769,ENSG00000100380,ENSG00000108518,ENSG00000117226,ENSG00000137474,ENSG00000116288,ENSG00000180644,ENSG00000213390,ENSG00000135114,ENSG00000175793,ENSG00000152465,ENSG00000172508,ENSG00000137563,ENSG00000138642,ENSG00000204264,ENSG00000173821,ENSG00000143742,ENSG00000205413,ENSG00000188191,ENSG00000114978,ENSG00000187446,ENSG00000130402,ENSG00000188312,ENSG00000071205,ENSG00000170312,ENSG00000170222,ENSG00000105887,ENSG00000110060,ENSG00000136436,ENSG00000185651,ENSG00000117394,ENSG00000135069,ENSG00000055332,ENSG00000239713,ENSG00000242372,ENSG00000153094,ENSG00000152229,ENSG00000213445,ENSG00000104687,ENSG00000123131,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000204472,ENSG00000184007,ENSG00000089685,ENSG00000044574,ENSG00000124587,ENSG00000130741,ENSG00000116030,ENSG00000072958,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000111229,ENSG00000179632,ENSG00000152778,ENSG00000185745,ENSG00000147065,ENSG00000204899,ENSG00000128578,ENSG00000180667,ENSG00000154001,ENSG00000126016,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000111348,ENSG00000132661,ENSG00000129675,ENSG00000118971,ENSG00000196954,ENSG00000183475,ENSG00000115155,ENSG00000101444,ENSG00000185650,ENSG00000100605,ENSG00000111331,ENSG00000074800,ENSG00000143476,ENSG00000084623,ENSG00000172803,ENSG00000122952,ENSG00000105220,ENSG00000143228,ENSG00000181467,ENSG00000136717,ENSG00000168421,ENSG00000134909,ENSG00000100385,ENSG00000130005,ENSG00000125148,ENSG00000131504,ENSG00000180574,ENSG00000075151,ENSG00000011485,ENSG00000067560,ENSG00000197417,ENSG00000154027,ENSG00000213928,ENSG00000189283,ENSG00000134202,ENSG00000075340,ENSG00000133026,ENSG00000113810,ENSG00000149294,ENSG00000185507,ENSG00000115267,ENSG00000087302,ENSG00000006625,ENSG00000151466,ENSG00000168961,ENSG00000172795,ENSG00000184887,ENSG00000141736,ENSG00000132963,ENSG00000132792,ENSG00000103994,ENSG00000118564,ENSG00000002549,ENSG00000187608,ENSG00000189369,ENSG00000021762,ENSG00000139579,ENSG00000042753,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000152253,ENSG00000079691,ENSG00000172936,ENSG00000124920,ENSG00000170860,ENSG00000171169,ENSG00000151239,ENSG00000179583,ENSG00000141030,ENSG00000189266,ENSG00000075624,ENSG00000096968,ENSG00000164164,ENSG00000136824,ENSG00000079999,ENSG00000165527,ENSG00000127666,ENSG00000223496,ENSG00000197956,ENSG00000109805,ENSG00000121579,ENSG00000148908,ENSG00000196072,ENSG00000138617,ENSG00000102931,ENSG00000116670,ENSG00000072571,ENSG00000055163,ENSG00000185880,ENSG00000123338,ENSG00000010270,ENSG00000142867,ENSG00000111335,ENSG00000143740,ENSG00000126432,ENSG00000198736,ENSG00000145337,ENSG00000138646,ENSG00000119318,ENSG00000172531,ENSG00000168765,ENSG00000153044,ENSG00000140284,ENSG00000137309,ENSG00000041357,ENSG00000254087,ENSG00000152601,ENSG00000092841,ENSG00000213366,ENSG00000140319,ENSG00000182628,ENSG00000196839,ENSG00000132388,ENSG00000148218,ENSG00000147168,ENSG00000134690,ENSG00000184575,ENSG00000177674,ENSG00000160753,ENSG00000178685,ENSG00000132256,ENSG00000111481,ENSG00000147889,ENSG00000140575,ENSG00000137193,ENSG00000155096,ENSG00000175104,ENSG00000196642,ENSG00000169554,ENSG00000127084,ENSG00000111859,ENSG00000170485 |
| GO:0042101 | T cell receptor complex | 0.0000108 | 124 | 739 | 19 | 0.0257104 | 0.1532258 | GO:CC | ENSG00000211805,ENSG00000211815,ENSG00000160654,ENSG00000211746,ENSG00000211698,ENSG00000211745,ENSG00000211786,ENSG00000211721,ENSG00000153563,ENSG00000211747,ENSG00000237254,ENSG00000172116,ENSG00000211810,ENSG00000013725,ENSG00000198821,ENSG00000211794,ENSG00000165283,ENSG00000167286,ENSG00000198851 |
| GO:0048471 | perinuclear region of cytoplasm | 0.0000132 | 724 | 739 | 57 | 0.0771313 | 0.0787293 | GO:CC | ENSG00000163599,ENSG00000117724,ENSG00000179218,ENSG00000154451,ENSG00000162654,ENSG00000100427,ENSG00000117560,ENSG00000173482,ENSG00000115415,ENSG00000156970,ENSG00000196924,ENSG00000150093,ENSG00000136167,ENSG00000111640,ENSG00000167914,ENSG00000103769,ENSG00000117226,ENSG00000116288,ENSG00000103966,ENSG00000130402,ENSG00000071205,ENSG00000105887,ENSG00000136436,ENSG00000055332,ENSG00000213445,ENSG00000119335,ENSG00000157601,ENSG00000204472,ENSG00000173786,ENSG00000179632,ENSG00000147065,ENSG00000166598,ENSG00000107317,ENSG00000125148,ENSG00000213719,ENSG00000087302,ENSG00000115339,ENSG00000148175,ENSG00000141736,ENSG00000118564,ENSG00000151239,ENSG00000197043,ENSG00000168329,ENSG00000197956,ENSG00000055163,ENSG00000184640,ENSG00000132386,ENSG00000142867,ENSG00000111335,ENSG00000143740,ENSG00000126432,ENSG00000138646,ENSG00000254087,ENSG00000139998,ENSG00000028137,ENSG00000175104,ENSG00000166794 |
| GO:0043235 | receptor complex | 0.0000171 | 503 | 739 | 44 | 0.0595399 | 0.0874751 | GO:CC | ENSG00000113721,ENSG00000211805,ENSG00000156886,ENSG00000211815,ENSG00000019582,ENSG00000130164,ENSG00000069702,ENSG00000221866,ENSG00000169252,ENSG00000160654,ENSG00000150093,ENSG00000211746,ENSG00000096996,ENSG00000211698,ENSG00000211745,ENSG00000211786,ENSG00000134539,ENSG00000211721,ENSG00000134352,ENSG00000139626,ENSG00000153563,ENSG00000005844,ENSG00000211747,ENSG00000237254,ENSG00000172116,ENSG00000148400,ENSG00000167723,ENSG00000166710,ENSG00000211810,ENSG00000013725,ENSG00000100385,ENSG00000198821,ENSG00000211794,ENSG00000165283,ENSG00000141736,ENSG00000167286,ENSG00000132670,ENSG00000254087,ENSG00000160255,ENSG00000198851,ENSG00000147168,ENSG00000028137,ENSG00000175104,ENSG00000081985 |
| GO:0030176 | integral component of endoplasmic reticulum membrane | 0.0000195 | 155 | 739 | 21 | 0.0284168 | 0.1354839 | GO:CC | ENSG00000204267,ENSG00000196126,ENSG00000179218,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000167004,ENSG00000099194,ENSG00000044574,ENSG00000166710,ENSG00000204642,ENSG00000204592,ENSG00000127022,ENSG00000127774,ENSG00000124155,ENSG00000144043,ENSG00000175283,ENSG00000140284,ENSG00000078124 |
| GO:0032991 | protein-containing complex | 0.0000195 | 5484 | 739 | 275 | 0.3721245 | 0.0501459 | GO:CC | ENSG00000172057,ENSG00000196169,ENSG00000179344,ENSG00000156587,ENSG00000138496,ENSG00000204267,ENSG00000113721,ENSG00000211805,ENSG00000196126,ENSG00000007402,ENSG00000229474,ENSG00000092010,ENSG00000156886,ENSG00000163599,ENSG00000117724,ENSG00000179218,ENSG00000211815,ENSG00000184357,ENSG00000135077,ENSG00000165891,ENSG00000080573,ENSG00000163840,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000159216,ENSG00000151502,ENSG00000160014,ENSG00000130164,ENSG00000115415,ENSG00000143870,ENSG00000186469,ENSG00000069702,ENSG00000100911,ENSG00000221866,ENSG00000101057,ENSG00000163029,ENSG00000223865,ENSG00000231389,ENSG00000156970,ENSG00000171848,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000118193,ENSG00000157216,ENSG00000150093,ENSG00000211746,ENSG00000105409,ENSG00000158966,ENSG00000138160,ENSG00000096996,ENSG00000077312,ENSG00000165617,ENSG00000211698,ENSG00000138795,ENSG00000211745,ENSG00000102554,ENSG00000189430,ENSG00000211786,ENSG00000134539,ENSG00000134308,ENSG00000211721,ENSG00000204397,ENSG00000108179,ENSG00000111640,ENSG00000183734,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000153563,ENSG00000103769,ENSG00000100380,ENSG00000183741,ENSG00000005844,ENSG00000103148,ENSG00000211747,ENSG00000185201,ENSG00000137474,ENSG00000196230,ENSG00000111602,ENSG00000124575,ENSG00000100918,ENSG00000204264,ENSG00000143742,ENSG00000105011,ENSG00000131018,ENSG00000196976,ENSG00000136274,ENSG00000188191,ENSG00000237254,ENSG00000130402,ENSG00000170312,ENSG00000105887,ENSG00000155846,ENSG00000185885,ENSG00000163359,ENSG00000185651,ENSG00000172116,ENSG00000131944,ENSG00000070018,ENSG00000139182,ENSG00000185304,ENSG00000152969,ENSG00000215305,ENSG00000239713,ENSG00000242372,ENSG00000169230,ENSG00000153094,ENSG00000065135,ENSG00000213445,ENSG00000119335,ENSG00000148400,ENSG00000167723,ENSG00000152256,ENSG00000171130,ENSG00000089685,ENSG00000163041,ENSG00000044574,ENSG00000130741,ENSG00000116030,ENSG00000007968,ENSG00000233954,ENSG00000072958,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000152778,ENSG00000204899,ENSG00000166197,ENSG00000204822,ENSG00000154001,ENSG00000126016,ENSG00000241258,ENSG00000253626,ENSG00000138071,ENSG00000100897,ENSG00000166598,ENSG00000132661,ENSG00000100342,ENSG00000118971,ENSG00000196954,ENSG00000177613,ENSG00000093009,ENSG00000185650,ENSG00000074800,ENSG00000143476,ENSG00000084623,ENSG00000143228,ENSG00000158869,ENSG00000172164,ENSG00000136717,ENSG00000013725,ENSG00000170881,ENSG00000100385,ENSG00000180574,ENSG00000075151,ENSG00000198821,ENSG00000011485,ENSG00000125944,ENSG00000183172,ENSG00000114166,ENSG00000213719,ENSG00000075340,ENSG00000133026,ENSG00000113810,ENSG00000144597,ENSG00000204642,ENSG00000087302,ENSG00000151743,ENSG00000151466,ENSG00000211794,ENSG00000158882,ENSG00000165283,ENSG00000172795,ENSG00000131747,ENSG00000171617,ENSG00000141736,ENSG00000204592,ENSG00000132182,ENSG00000132792,ENSG00000083444,ENSG00000118564,ENSG00000213626,ENSG00000167286,ENSG00000189369,ENSG00000139579,ENSG00000162676,ENSG00000106462,ENSG00000042753,ENSG00000070831,ENSG00000152253,ENSG00000079691,ENSG00000172936,ENSG00000112996,ENSG00000170860,ENSG00000118705,ENSG00000166035,ENSG00000141030,ENSG00000074071,ENSG00000132670,ENSG00000075624,ENSG00000128394,ENSG00000130348,ENSG00000136824,ENSG00000079999,ENSG00000113068,ENSG00000117155,ENSG00000162385,ENSG00000127666,ENSG00000159111,ENSG00000223496,ENSG00000127022,ENSG00000109805,ENSG00000121579,ENSG00000196072,ENSG00000184897,ENSG00000116670,ENSG00000184640,ENSG00000127774,ENSG00000123338,ENSG00000109536,ENSG00000128272,ENSG00000142867,ENSG00000114126,ENSG00000109390,ENSG00000143740,ENSG00000124155,ENSG00000214022,ENSG00000145337,ENSG00000049541,ENSG00000104738,ENSG00000119318,ENSG00000172531,ENSG00000178691,ENSG00000137309,ENSG00000041357,ENSG00000125354,ENSG00000125870,ENSG00000254087,ENSG00000160255,ENSG00000189306,ENSG00000104472,ENSG00000092841,ENSG00000140319,ENSG00000182628,ENSG00000127951,ENSG00000101082,ENSG00000164576,ENSG00000197409,ENSG00000173660,ENSG00000137312,ENSG00000198851,ENSG00000143321,ENSG00000136104,ENSG00000242574,ENSG00000147168,ENSG00000134690,ENSG00000184575,ENSG00000011007,ENSG00000154518,ENSG00000028137,ENSG00000111481,ENSG00000140575,ENSG00000111450,ENSG00000175104,ENSG00000110218,ENSG00000113387,ENSG00000166794,ENSG00000170485,ENSG00000081985 |
| GO:0005789 | endoplasmic reticulum membrane | 0.0000212 | 1075 | 739 | 75 | 0.1014885 | 0.0697674 | GO:CC | ENSG00000172057,ENSG00000134824,ENSG00000164308,ENSG00000204267,ENSG00000196126,ENSG00000248905,ENSG00000109956,ENSG00000179218,ENSG00000057704,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000198513,ENSG00000143870,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000167004,ENSG00000121039,ENSG00000123179,ENSG00000099194,ENSG00000172292,ENSG00000128335,ENSG00000103512,ENSG00000134321,ENSG00000143742,ENSG00000170312,ENSG00000139182,ENSG00000171603,ENSG00000165949,ENSG00000065135,ENSG00000148400,ENSG00000157601,ENSG00000044574,ENSG00000166710,ENSG00000253626,ENSG00000166598,ENSG00000107317,ENSG00000196954,ENSG00000115155,ENSG00000134909,ENSG00000158006,ENSG00000170881,ENSG00000139921,ENSG00000128039,ENSG00000067560,ENSG00000204642,ENSG00000204592,ENSG00000132182,ENSG00000083444,ENSG00000021762,ENSG00000198843,ENSG00000070831,ENSG00000124920,ENSG00000118705,ENSG00000171302,ENSG00000197142,ENSG00000171954,ENSG00000109084,ENSG00000127022,ENSG00000138018,ENSG00000138617,ENSG00000127774,ENSG00000010270,ENSG00000134049,ENSG00000124155,ENSG00000145337,ENSG00000144043,ENSG00000175283,ENSG00000140284,ENSG00000177674,ENSG00000169223,ENSG00000111481,ENSG00000078124,ENSG00000110218 |
| GO:0042175 | nuclear outer membrane-endoplasmic reticulum membrane network | 0.0000234 | 1098 | 739 | 76 | 0.1028417 | 0.0692168 | GO:CC | ENSG00000172057,ENSG00000134824,ENSG00000164308,ENSG00000204267,ENSG00000196126,ENSG00000248905,ENSG00000109956,ENSG00000179218,ENSG00000057704,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000198513,ENSG00000143870,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000167004,ENSG00000121039,ENSG00000123179,ENSG00000099194,ENSG00000172292,ENSG00000128335,ENSG00000103512,ENSG00000134321,ENSG00000143742,ENSG00000131018,ENSG00000170312,ENSG00000139182,ENSG00000171603,ENSG00000165949,ENSG00000065135,ENSG00000148400,ENSG00000157601,ENSG00000044574,ENSG00000166710,ENSG00000253626,ENSG00000166598,ENSG00000107317,ENSG00000196954,ENSG00000115155,ENSG00000134909,ENSG00000158006,ENSG00000170881,ENSG00000139921,ENSG00000128039,ENSG00000067560,ENSG00000204642,ENSG00000204592,ENSG00000132182,ENSG00000083444,ENSG00000021762,ENSG00000198843,ENSG00000070831,ENSG00000124920,ENSG00000118705,ENSG00000171302,ENSG00000197142,ENSG00000171954,ENSG00000109084,ENSG00000127022,ENSG00000138018,ENSG00000138617,ENSG00000127774,ENSG00000010270,ENSG00000134049,ENSG00000124155,ENSG00000145337,ENSG00000144043,ENSG00000175283,ENSG00000140284,ENSG00000177674,ENSG00000169223,ENSG00000111481,ENSG00000078124,ENSG00000110218 |
| GO:0042613 | MHC class II protein complex | 0.0000286 | 16 | 739 | 7 | 0.0094723 | 0.4375000 | GO:CC | ENSG00000179344,ENSG00000196126,ENSG00000196735,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000242574 |
| GO:0005768 | endosome | 0.0000312 | 935 | 739 | 67 | 0.0906631 | 0.0716578 | GO:CC | ENSG00000179344,ENSG00000196126,ENSG00000135077,ENSG00000100427,ENSG00000163840,ENSG00000196735,ENSG00000019582,ENSG00000151502,ENSG00000130164,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000105639,ENSG00000142089,ENSG00000169252,ENSG00000167004,ENSG00000117984,ENSG00000150093,ENSG00000167461,ENSG00000125249,ENSG00000179051,ENSG00000232810,ENSG00000103769,ENSG00000180644,ENSG00000103966,ENSG00000077984,ENSG00000172116,ENSG00000070018,ENSG00000171603,ENSG00000215305,ENSG00000041353,ENSG00000171130,ENSG00000184007,ENSG00000166710,ENSG00000104805,ENSG00000172803,ENSG00000181467,ENSG00000136717,ENSG00000100299,ENSG00000134909,ENSG00000163131,ENSG00000100385,ENSG00000067560,ENSG00000132932,ENSG00000185507,ENSG00000204642,ENSG00000141736,ENSG00000204592,ENSG00000042753,ENSG00000178996,ENSG00000079691,ENSG00000172936,ENSG00000197043,ENSG00000113369,ENSG00000096968,ENSG00000165527,ENSG00000127666,ENSG00000010270,ENSG00000140450,ENSG00000129968,ENSG00000139998,ENSG00000101082,ENSG00000137312,ENSG00000242574,ENSG00000147168,ENSG00000160753,ENSG00000175104 |
| GO:0098802 | plasma membrane signaling receptor complex | 0.0000380 | 293 | 739 | 30 | 0.0405954 | 0.1023891 | GO:CC | ENSG00000211805,ENSG00000156886,ENSG00000211815,ENSG00000160654,ENSG00000150093,ENSG00000211746,ENSG00000096996,ENSG00000211698,ENSG00000211745,ENSG00000211786,ENSG00000211721,ENSG00000134352,ENSG00000139626,ENSG00000153563,ENSG00000005844,ENSG00000211747,ENSG00000237254,ENSG00000172116,ENSG00000166710,ENSG00000211810,ENSG00000013725,ENSG00000100385,ENSG00000198821,ENSG00000211794,ENSG00000165283,ENSG00000167286,ENSG00000254087,ENSG00000160255,ENSG00000198851,ENSG00000175104 |
| GO:0031227 | intrinsic component of endoplasmic reticulum membrane | 0.0000380 | 163 | 739 | 21 | 0.0284168 | 0.1288344 | GO:CC | ENSG00000204267,ENSG00000196126,ENSG00000179218,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000167004,ENSG00000099194,ENSG00000044574,ENSG00000166710,ENSG00000204642,ENSG00000204592,ENSG00000127022,ENSG00000127774,ENSG00000124155,ENSG00000144043,ENSG00000175283,ENSG00000140284,ENSG00000078124 |
| GO:0098797 | plasma membrane protein complex | 0.0000756 | 680 | 739 | 52 | 0.0703654 | 0.0764706 | GO:CC | ENSG00000179344,ENSG00000211805,ENSG00000196126,ENSG00000007402,ENSG00000156886,ENSG00000211815,ENSG00000196735,ENSG00000019582,ENSG00000160014,ENSG00000186469,ENSG00000069702,ENSG00000223865,ENSG00000231389,ENSG00000160654,ENSG00000150093,ENSG00000211746,ENSG00000105409,ENSG00000158966,ENSG00000096996,ENSG00000211698,ENSG00000211745,ENSG00000211786,ENSG00000211721,ENSG00000134352,ENSG00000139626,ENSG00000153563,ENSG00000005844,ENSG00000211747,ENSG00000237254,ENSG00000172116,ENSG00000070018,ENSG00000065135,ENSG00000116030,ENSG00000166710,ENSG00000211810,ENSG00000158869,ENSG00000172164,ENSG00000013725,ENSG00000100385,ENSG00000198821,ENSG00000204642,ENSG00000211794,ENSG00000165283,ENSG00000204592,ENSG00000167286,ENSG00000042753,ENSG00000254087,ENSG00000160255,ENSG00000137312,ENSG00000198851,ENSG00000242574,ENSG00000175104 |
| GO:0042824 | MHC class I peptide loading complex | 0.0001005 | 8 | 739 | 5 | 0.0067659 | 0.6250000 | GO:CC | ENSG00000204267,ENSG00000179218,ENSG00000231925,ENSG00000167004,ENSG00000166710 |
| GO:0010008 | endosome membrane | 0.0001418 | 481 | 739 | 40 | 0.0541272 | 0.0831601 | GO:CC | ENSG00000196126,ENSG00000163840,ENSG00000196735,ENSG00000130164,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000142089,ENSG00000169252,ENSG00000167004,ENSG00000117984,ENSG00000167461,ENSG00000125249,ENSG00000179051,ENSG00000103769,ENSG00000103966,ENSG00000172116,ENSG00000070018,ENSG00000215305,ENSG00000041353,ENSG00000171130,ENSG00000166710,ENSG00000181467,ENSG00000134909,ENSG00000185507,ENSG00000204642,ENSG00000141736,ENSG00000204592,ENSG00000042753,ENSG00000178996,ENSG00000172936,ENSG00000197043,ENSG00000165527,ENSG00000127666,ENSG00000010270,ENSG00000129968,ENSG00000139998,ENSG00000101082,ENSG00000242574,ENSG00000175104 |
| GO:0070161 | anchoring junction | 0.0002303 | 785 | 739 | 56 | 0.0757781 | 0.0713376 | GO:CC | ENSG00000113721,ENSG00000248905,ENSG00000072110,ENSG00000179218,ENSG00000002834,ENSG00000100427,ENSG00000173482,ENSG00000164111,ENSG00000167004,ENSG00000196924,ENSG00000127947,ENSG00000150093,ENSG00000136167,ENSG00000172757,ENSG00000134308,ENSG00000139626,ENSG00000108518,ENSG00000134765,ENSG00000073008,ENSG00000187446,ENSG00000130402,ENSG00000117394,ENSG00000148400,ENSG00000044574,ENSG00000064666,ENSG00000166710,ENSG00000111229,ENSG00000147065,ENSG00000166974,ENSG00000126016,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000181467,ENSG00000172164,ENSG00000067560,ENSG00000172270,ENSG00000173517,ENSG00000002549,ENSG00000070831,ENSG00000151239,ENSG00000197043,ENSG00000075624,ENSG00000096968,ENSG00000165527,ENSG00000117155,ENSG00000105697,ENSG00000137309,ENSG00000160255,ENSG00000137312,ENSG00000198851,ENSG00000139926,ENSG00000140575,ENSG00000110218,ENSG00000166794,ENSG00000111859 |
| GO:0042105 | alpha-beta T cell receptor complex | 0.0002303 | 5 | 739 | 4 | 0.0054127 | 0.8000000 | GO:CC | ENSG00000160654,ENSG00000198821,ENSG00000167286,ENSG00000198851 |
| GO:0098796 | membrane protein complex | 0.0002818 | 1285 | 739 | 81 | 0.1096076 | 0.0630350 | GO:CC | ENSG00000172057,ENSG00000179344,ENSG00000204267,ENSG00000211805,ENSG00000196126,ENSG00000007402,ENSG00000156886,ENSG00000179218,ENSG00000211815,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000151502,ENSG00000160014,ENSG00000186469,ENSG00000069702,ENSG00000223865,ENSG00000231389,ENSG00000160654,ENSG00000167004,ENSG00000150093,ENSG00000211746,ENSG00000105409,ENSG00000158966,ENSG00000096996,ENSG00000211698,ENSG00000211745,ENSG00000211786,ENSG00000211721,ENSG00000108179,ENSG00000134352,ENSG00000139626,ENSG00000153563,ENSG00000005844,ENSG00000211747,ENSG00000143742,ENSG00000131018,ENSG00000237254,ENSG00000172116,ENSG00000070018,ENSG00000215305,ENSG00000065135,ENSG00000171130,ENSG00000116030,ENSG00000233954,ENSG00000072958,ENSG00000166710,ENSG00000211810,ENSG00000158869,ENSG00000172164,ENSG00000013725,ENSG00000170881,ENSG00000100385,ENSG00000198821,ENSG00000183172,ENSG00000213719,ENSG00000204642,ENSG00000151466,ENSG00000211794,ENSG00000158882,ENSG00000165283,ENSG00000204592,ENSG00000167286,ENSG00000042753,ENSG00000118705,ENSG00000127774,ENSG00000109390,ENSG00000143740,ENSG00000124155,ENSG00000145337,ENSG00000254087,ENSG00000160255,ENSG00000101082,ENSG00000173660,ENSG00000137312,ENSG00000198851,ENSG00000242574,ENSG00000154518,ENSG00000111481,ENSG00000111450,ENSG00000175104 |
| GO:0015629 | actin cytoskeleton | 0.0003106 | 517 | 739 | 41 | 0.0554804 | 0.0793037 | GO:CC | ENSG00000183688,ENSG00000248905,ENSG00000072110,ENSG00000002834,ENSG00000155657,ENSG00000125868,ENSG00000196924,ENSG00000127947,ENSG00000136167,ENSG00000172757,ENSG00000117228,ENSG00000130592,ENSG00000137474,ENSG00000130402,ENSG00000011426,ENSG00000105887,ENSG00000117394,ENSG00000204472,ENSG00000064666,ENSG00000111229,ENSG00000152778,ENSG00000126016,ENSG00000138071,ENSG00000131236,ENSG00000136717,ENSG00000134909,ENSG00000114166,ENSG00000075340,ENSG00000133026,ENSG00000165283,ENSG00000173517,ENSG00000158321,ENSG00000079691,ENSG00000151239,ENSG00000075624,ENSG00000079999,ENSG00000184640,ENSG00000198736,ENSG00000092841,ENSG00000137312,ENSG00000140575 |
| GO:0005938 | cell cortex | 0.0006945 | 326 | 739 | 29 | 0.0392422 | 0.0889571 | GO:CC | ENSG00000002834,ENSG00000125868,ENSG00000125864,ENSG00000196924,ENSG00000172757,ENSG00000108518,ENSG00000137474,ENSG00000130402,ENSG00000011426,ENSG00000117394,ENSG00000073910,ENSG00000138071,ENSG00000131236,ENSG00000074800,ENSG00000134909,ENSG00000067560,ENSG00000165304,ENSG00000133026,ENSG00000070831,ENSG00000075624,ENSG00000165527,ENSG00000105697,ENSG00000184640,ENSG00000125354,ENSG00000067840,ENSG00000137312,ENSG00000177674,ENSG00000175104,ENSG00000111859 |
| GO:0005856 | cytoskeleton | 0.0011193 | 2263 | 739 | 124 | 0.1677943 | 0.0547945 | GO:CC | ENSG00000196169,ENSG00000183688,ENSG00000248905,ENSG00000072110,ENSG00000129595,ENSG00000117724,ENSG00000157423,ENSG00000163492,ENSG00000002834,ENSG00000155657,ENSG00000160014,ENSG00000034510,ENSG00000113368,ENSG00000156970,ENSG00000125868,ENSG00000105639,ENSG00000125864,ENSG00000117632,ENSG00000196924,ENSG00000118193,ENSG00000112029,ENSG00000127947,ENSG00000136167,ENSG00000167461,ENSG00000138160,ENSG00000172757,ENSG00000179051,ENSG00000117228,ENSG00000138180,ENSG00000126787,ENSG00000133739,ENSG00000100749,ENSG00000111640,ENSG00000132646,ENSG00000103769,ENSG00000108518,ENSG00000130592,ENSG00000137474,ENSG00000196230,ENSG00000143543,ENSG00000131018,ENSG00000187446,ENSG00000130402,ENSG00000011426,ENSG00000170312,ENSG00000105887,ENSG00000136436,ENSG00000117394,ENSG00000152969,ENSG00000242372,ENSG00000123416,ENSG00000152229,ENSG00000065135,ENSG00000122971,ENSG00000157601,ENSG00000204472,ENSG00000089685,ENSG00000064666,ENSG00000111229,ENSG00000152778,ENSG00000147065,ENSG00000166974,ENSG00000204899,ENSG00000129422,ENSG00000126016,ENSG00000073910,ENSG00000138071,ENSG00000131236,ENSG00000111348,ENSG00000093009,ENSG00000143476,ENSG00000172164,ENSG00000136717,ENSG00000134909,ENSG00000131504,ENSG00000067560,ENSG00000154027,ENSG00000114166,ENSG00000075340,ENSG00000133026,ENSG00000087302,ENSG00000151466,ENSG00000115902,ENSG00000165283,ENSG00000173517,ENSG00000148175,ENSG00000131747,ENSG00000171617,ENSG00000132792,ENSG00000158321,ENSG00000176101,ENSG00000070831,ENSG00000079691,ENSG00000151239,ENSG00000153790,ENSG00000147234,ENSG00000066279,ENSG00000075624,ENSG00000096968,ENSG00000079999,ENSG00000117155,ENSG00000196072,ENSG00000102931,ENSG00000116670,ENSG00000072571,ENSG00000184640,ENSG00000128272,ENSG00000124688,ENSG00000142867,ENSG00000114126,ENSG00000146112,ENSG00000198736,ENSG00000132321,ENSG00000125354,ENSG00000092841,ENSG00000182628,ENSG00000137312,ENSG00000134690,ENSG00000160753,ENSG00000139926,ENSG00000140575,ENSG00000196642,ENSG00000127084,ENSG00000111859 |
| GO:0045121 | membrane raft | 0.0011886 | 320 | 739 | 28 | 0.0378890 | 0.0875000 | GO:CC | ENSG00000142634,ENSG00000100427,ENSG00000117560,ENSG00000205336,ENSG00000117984,ENSG00000150093,ENSG00000232810,ENSG00000118777,ENSG00000153563,ENSG00000116288,ENSG00000196230,ENSG00000117394,ENSG00000070018,ENSG00000123416,ENSG00000065135,ENSG00000181467,ENSG00000075340,ENSG00000172270,ENSG00000165283,ENSG00000148175,ENSG00000111863,ENSG00000096968,ENSG00000142867,ENSG00000254087,ENSG00000160255,ENSG00000137312,ENSG00000028137,ENSG00000140575 |
| GO:0005634 | nucleus | 0.0011886 | 7486 | 739 | 344 | 0.4654939 | 0.0459524 | GO:CC | ENSG00000100453,ENSG00000004468,ENSG00000150687,ENSG00000148773,ENSG00000152217,ENSG00000156587,ENSG00000138496,ENSG00000204267,ENSG00000113721,ENSG00000176083,ENSG00000229474,ENSG00000092010,ENSG00000248905,ENSG00000073861,ENSG00000132530,ENSG00000117724,ENSG00000125347,ENSG00000179218,ENSG00000184357,ENSG00000135077,ENSG00000165891,ENSG00000162654,ENSG00000155657,ENSG00000163840,ENSG00000097021,ENSG00000123485,ENSG00000019582,ENSG00000142669,ENSG00000117560,ENSG00000144354,ENSG00000072135,ENSG00000164649,ENSG00000159216,ENSG00000160014,ENSG00000127124,ENSG00000115415,ENSG00000100911,ENSG00000197928,ENSG00000130511,ENSG00000124191,ENSG00000198046,ENSG00000113368,ENSG00000101057,ENSG00000177156,ENSG00000163029,ENSG00000170315,ENSG00000166503,ENSG00000156970,ENSG00000169252,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000175550,ENSG00000118193,ENSG00000112029,ENSG00000127947,ENSG00000157216,ENSG00000123609,ENSG00000165512,ENSG00000173848,ENSG00000138160,ENSG00000077312,ENSG00000165617,ENSG00000111206,ENSG00000172757,ENSG00000138795,ENSG00000102554,ENSG00000179051,ENSG00000189430,ENSG00000099194,ENSG00000126787,ENSG00000176890,ENSG00000176293,ENSG00000100749,ENSG00000111640,ENSG00000118777,ENSG00000183734,ENSG00000132646,ENSG00000108518,ENSG00000183741,ENSG00000131171,ENSG00000189319,ENSG00000116288,ENSG00000196230,ENSG00000111602,ENSG00000213390,ENSG00000135114,ENSG00000134321,ENSG00000175793,ENSG00000103966,ENSG00000124575,ENSG00000189420,ENSG00000023572,ENSG00000100918,ENSG00000156463,ENSG00000137563,ENSG00000138642,ENSG00000204264,ENSG00000173821,ENSG00000105011,ENSG00000157045,ENSG00000051341,ENSG00000131018,ENSG00000196976,ENSG00000136274,ENSG00000114978,ENSG00000187446,ENSG00000130402,ENSG00000188312,ENSG00000011426,ENSG00000170312,ENSG00000105887,ENSG00000110060,ENSG00000155846,ENSG00000136436,ENSG00000185651,ENSG00000164830,ENSG00000117394,ENSG00000131944,ENSG00000171603,ENSG00000125462,ENSG00000165949,ENSG00000185304,ENSG00000099840,ENSG00000092853,ENSG00000055332,ENSG00000239713,ENSG00000242372,ENSG00000169230,ENSG00000213445,ENSG00000123131,ENSG00000159200,ENSG00000122971,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000152256,ENSG00000204472,ENSG00000184007,ENSG00000089685,ENSG00000189159,ENSG00000121297,ENSG00000163041,ENSG00000044574,ENSG00000133315,ENSG00000188612,ENSG00000181938,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000118263,ENSG00000132274,ENSG00000173786,ENSG00000111229,ENSG00000104805,ENSG00000179632,ENSG00000163545,ENSG00000147065,ENSG00000142556,ENSG00000166454,ENSG00000129422,ENSG00000166197,ENSG00000154001,ENSG00000126016,ENSG00000241258,ENSG00000253626,ENSG00000131931,ENSG00000171970,ENSG00000138071,ENSG00000100897,ENSG00000166598,ENSG00000157985,ENSG00000107317,ENSG00000132661,ENSG00000225921,ENSG00000118971,ENSG00000129534,ENSG00000177613,ENSG00000093009,ENSG00000101444,ENSG00000185650,ENSG00000111331,ENSG00000074800,ENSG00000143476,ENSG00000122952,ENSG00000105220,ENSG00000143228,ENSG00000171222,ENSG00000053254,ENSG00000145649,ENSG00000136717,ENSG00000071994,ENSG00000134909,ENSG00000130005,ENSG00000125148,ENSG00000131504,ENSG00000011485,ENSG00000067560,ENSG00000196436,ENSG00000132932,ENSG00000213928,ENSG00000125944,ENSG00000183172,ENSG00000114166,ENSG00000189283,ENSG00000213719,ENSG00000165304,ENSG00000134202,ENSG00000133026,ENSG00000113810,ENSG00000185507,ENSG00000100298,ENSG00000144597,ENSG00000115267,ENSG00000204256,ENSG00000087302,ENSG00000168961,ENSG00000122122,ENSG00000180938,ENSG00000122877,ENSG00000165283,ENSG00000172795,ENSG00000131747,ENSG00000171617,ENSG00000141736,ENSG00000132963,ENSG00000162702,ENSG00000132182,ENSG00000132792,ENSG00000103994,ENSG00000158321,ENSG00000237190,ENSG00000174371,ENSG00000160877,ENSG00000002549,ENSG00000213626,ENSG00000166881,ENSG00000187608,ENSG00000139579,ENSG00000103495,ENSG00000162676,ENSG00000068489,ENSG00000106462,ENSG00000176101,ENSG00000104765,ENSG00000152253,ENSG00000079691,ENSG00000172936,ENSG00000124920,ENSG00000170860,ENSG00000171169,ENSG00000164088,ENSG00000243660,ENSG00000179583,ENSG00000141030,ENSG00000197142,ENSG00000189266,ENSG00000066279,ENSG00000075624,ENSG00000096968,ENSG00000164164,ENSG00000176542,ENSG00000128394,ENSG00000109674,ENSG00000136824,ENSG00000079999,ENSG00000117155,ENSG00000162385,ENSG00000159111,ENSG00000109084,ENSG00000223496,ENSG00000197956,ENSG00000109805,ENSG00000121579,ENSG00000148908,ENSG00000138617,ENSG00000184897,ENSG00000102931,ENSG00000116670,ENSG00000055163,ENSG00000185880,ENSG00000109536,ENSG00000128272,ENSG00000148337,ENSG00000124688,ENSG00000120709,ENSG00000142867,ENSG00000111335,ENSG00000114126,ENSG00000126432,ENSG00000214022,ENSG00000198736,ENSG00000049541,ENSG00000104738,ENSG00000119318,ENSG00000172531,ENSG00000178691,ENSG00000257390,ENSG00000153044,ENSG00000137309,ENSG00000041357,ENSG00000125870,ENSG00000254087,ENSG00000152601,ENSG00000189306,ENSG00000104472,ENSG00000091127,ENSG00000140319,ENSG00000137310,ENSG00000101082,ENSG00000164576,ENSG00000197409,ENSG00000172667,ENSG00000137312,ENSG00000143321,ENSG00000136104,ENSG00000089693,ENSG00000155090,ENSG00000148218,ENSG00000134690,ENSG00000184575,ENSG00000177674,ENSG00000011007,ENSG00000028137,ENSG00000160753,ENSG00000178685,ENSG00000132256,ENSG00000147889,ENSG00000140575,ENSG00000137193,ENSG00000160404,ENSG00000155096,ENSG00000175104,ENSG00000196642,ENSG00000169554,ENSG00000120280,ENSG00000113387,ENSG00000166794,ENSG00000111859,ENSG00000147180,ENSG00000170485,ENSG00000130818 |
| GO:0005783 | endoplasmic reticulum | 0.0011886 | 1810 | 739 | 103 | 0.1393775 | 0.0569061 | GO:CC | ENSG00000172057,ENSG00000134824,ENSG00000150687,ENSG00000164308,ENSG00000119922,ENSG00000204267,ENSG00000196126,ENSG00000109956,ENSG00000179218,ENSG00000100427,ENSG00000080573,ENSG00000057704,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000198513,ENSG00000143870,ENSG00000223865,ENSG00000231389,ENSG00000167004,ENSG00000146674,ENSG00000121039,ENSG00000105409,ENSG00000111885,ENSG00000123179,ENSG00000099194,ENSG00000172292,ENSG00000167123,ENSG00000116288,ENSG00000134321,ENSG00000103966,ENSG00000143742,ENSG00000077984,ENSG00000187446,ENSG00000163359,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000165949,ENSG00000123131,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000089127,ENSG00000044574,ENSG00000166710,ENSG00000104805,ENSG00000253626,ENSG00000166598,ENSG00000107317,ENSG00000100342,ENSG00000196954,ENSG00000115155,ENSG00000155368,ENSG00000100299,ENSG00000134909,ENSG00000158006,ENSG00000170881,ENSG00000139921,ENSG00000128039,ENSG00000125944,ENSG00000049449,ENSG00000204642,ENSG00000101474,ENSG00000148175,ENSG00000132963,ENSG00000132182,ENSG00000083444,ENSG00000129625,ENSG00000021762,ENSG00000198843,ENSG00000104765,ENSG00000124920,ENSG00000118705,ENSG00000128294,ENSG00000171302,ENSG00000178719,ENSG00000166035,ENSG00000197142,ENSG00000079999,ENSG00000171954,ENSG00000109084,ENSG00000127022,ENSG00000026751,ENSG00000138617,ENSG00000184154,ENSG00000090520,ENSG00000049239,ENSG00000127774,ENSG00000134049,ENSG00000124155,ENSG00000175283,ENSG00000140284,ENSG00000006756,ENSG00000213366,ENSG00000183726,ENSG00000155660,ENSG00000177674,ENSG00000169223,ENSG00000160404,ENSG00000078124,ENSG00000110218,ENSG00000166794 |
| GO:0098857 | membrane microdomain | 0.0012026 | 321 | 739 | 28 | 0.0378890 | 0.0872274 | GO:CC | ENSG00000142634,ENSG00000100427,ENSG00000117560,ENSG00000205336,ENSG00000117984,ENSG00000150093,ENSG00000232810,ENSG00000118777,ENSG00000153563,ENSG00000116288,ENSG00000196230,ENSG00000117394,ENSG00000070018,ENSG00000123416,ENSG00000065135,ENSG00000181467,ENSG00000075340,ENSG00000172270,ENSG00000165283,ENSG00000148175,ENSG00000111863,ENSG00000096968,ENSG00000142867,ENSG00000254087,ENSG00000160255,ENSG00000137312,ENSG00000028137,ENSG00000140575 |
| GO:0005819 | spindle | 0.0017607 | 363 | 739 | 30 | 0.0405954 | 0.0826446 | GO:CC | ENSG00000117724,ENSG00000160014,ENSG00000156970,ENSG00000118193,ENSG00000112029,ENSG00000138160,ENSG00000179051,ENSG00000126787,ENSG00000100749,ENSG00000103769,ENSG00000143543,ENSG00000170312,ENSG00000089685,ENSG00000166974,ENSG00000204899,ENSG00000129422,ENSG00000073910,ENSG00000131504,ENSG00000133026,ENSG00000087302,ENSG00000070831,ENSG00000066279,ENSG00000102931,ENSG00000116670,ENSG00000124688,ENSG00000114126,ENSG00000125354,ENSG00000182628,ENSG00000134690,ENSG00000111859 |
| GO:0001772 | immunological synapse | 0.0018583 | 39 | 739 | 8 | 0.0108254 | 0.2051282 | GO:CC | ENSG00000100453,ENSG00000135077,ENSG00000145649,ENSG00000168421,ENSG00000013725,ENSG00000165283,ENSG00000142867,ENSG00000198851 |
| GO:0098589 | membrane region | 0.0022470 | 334 | 739 | 28 | 0.0378890 | 0.0838323 | GO:CC | ENSG00000142634,ENSG00000100427,ENSG00000117560,ENSG00000205336,ENSG00000117984,ENSG00000150093,ENSG00000232810,ENSG00000118777,ENSG00000153563,ENSG00000116288,ENSG00000196230,ENSG00000117394,ENSG00000070018,ENSG00000123416,ENSG00000065135,ENSG00000181467,ENSG00000075340,ENSG00000172270,ENSG00000165283,ENSG00000148175,ENSG00000111863,ENSG00000096968,ENSG00000142867,ENSG00000254087,ENSG00000160255,ENSG00000137312,ENSG00000028137,ENSG00000140575 |
| GO:0005576 | extracellular region | 0.0031530 | 4548 | 739 | 220 | 0.2976996 | 0.0483729 | GO:CC | ENSG00000137441,ENSG00000004468,ENSG00000150687,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000072110,ENSG00000221963,ENSG00000108679,ENSG00000109956,ENSG00000179218,ENSG00000115523,ENSG00000159674,ENSG00000160932,ENSG00000162654,ENSG00000080573,ENSG00000134184,ENSG00000155657,ENSG00000089692,ENSG00000097021,ENSG00000182054,ENSG00000163421,ENSG00000019582,ENSG00000142669,ENSG00000117560,ENSG00000203747,ENSG00000130164,ENSG00000143870,ENSG00000186469,ENSG00000069702,ENSG00000091129,ENSG00000100911,ENSG00000205336,ENSG00000164111,ENSG00000177156,ENSG00000170315,ENSG00000166503,ENSG00000213512,ENSG00000125868,ENSG00000117632,ENSG00000167004,ENSG00000196924,ENSG00000146674,ENSG00000169442,ENSG00000065911,ENSG00000120057,ENSG00000117984,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000105409,ENSG00000172331,ENSG00000173114,ENSG00000149328,ENSG00000172757,ENSG00000111537,ENSG00000111885,ENSG00000112139,ENSG00000232810,ENSG00000183691,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000111640,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000153563,ENSG00000103769,ENSG00000100380,ENSG00000108518,ENSG00000128335,ENSG00000128284,ENSG00000131171,ENSG00000005844,ENSG00000130592,ENSG00000116288,ENSG00000196230,ENSG00000134765,ENSG00000180644,ENSG00000122121,ENSG00000073008,ENSG00000075234,ENSG00000175793,ENSG00000103966,ENSG00000137563,ENSG00000204264,ENSG00000077984,ENSG00000114978,ENSG00000187446,ENSG00000130402,ENSG00000170312,ENSG00000167618,ENSG00000163359,ENSG00000117394,ENSG00000172116,ENSG00000135069,ENSG00000070018,ENSG00000171603,ENSG00000099840,ENSG00000242372,ENSG00000124299,ENSG00000065135,ENSG00000104687,ENSG00000213281,ENSG00000163520,ENSG00000110080,ENSG00000123131,ENSG00000148400,ENSG00000041353,ENSG00000089127,ENSG00000163041,ENSG00000044574,ENSG00000130741,ENSG00000064666,ENSG00000072958,ENSG00000173786,ENSG00000166710,ENSG00000111229,ENSG00000104805,ENSG00000147065,ENSG00000129422,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000107317,ENSG00000111348,ENSG00000100342,ENSG00000156234,ENSG00000021355,ENSG00000196954,ENSG00000101444,ENSG00000111331,ENSG00000074800,ENSG00000084623,ENSG00000105220,ENSG00000181467,ENSG00000145649,ENSG00000071994,ENSG00000155368,ENSG00000100299,ENSG00000013725,ENSG00000163131,ENSG00000067560,ENSG00000196436,ENSG00000064886,ENSG00000213719,ENSG00000213064,ENSG00000134202,ENSG00000133026,ENSG00000174684,ENSG00000149294,ENSG00000144597,ENSG00000204642,ENSG00000143727,ENSG00000006625,ENSG00000168961,ENSG00000115339,ENSG00000115902,ENSG00000172270,ENSG00000148175,ENSG00000204592,ENSG00000083444,ENSG00000002549,ENSG00000187608,ENSG00000130812,ENSG00000153310,ENSG00000178996,ENSG00000070831,ENSG00000079691,ENSG00000101079,ENSG00000171302,ENSG00000166035,ENSG00000197043,ENSG00000132670,ENSG00000075624,ENSG00000075239,ENSG00000136824,ENSG00000165527,ENSG00000105612,ENSG00000105697,ENSG00000127022,ENSG00000197956,ENSG00000121579,ENSG00000055163,ENSG00000132386,ENSG00000123338,ENSG00000140450,ENSG00000126432,ENSG00000196834,ENSG00000172531,ENSG00000168765,ENSG00000140284,ENSG00000041357,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000092841,ENSG00000213366,ENSG00000140319,ENSG00000127951,ENSG00000155660,ENSG00000131019,ENSG00000197409,ENSG00000131873,ENSG00000137312,ENSG00000196839,ENSG00000132388,ENSG00000143321,ENSG00000148218,ENSG00000134690,ENSG00000103489,ENSG00000011007,ENSG00000028137,ENSG00000169223,ENSG00000140575,ENSG00000160404,ENSG00000111450,ENSG00000113387,ENSG00000166794 |
| GO:0005788 | endoplasmic reticulum lumen | 0.0031610 | 307 | 739 | 26 | 0.0351827 | 0.0846906 | GO:CC | ENSG00000150687,ENSG00000164308,ENSG00000179218,ENSG00000080573,ENSG00000143870,ENSG00000167004,ENSG00000146674,ENSG00000167123,ENSG00000163359,ENSG00000044574,ENSG00000166710,ENSG00000104805,ENSG00000166598,ENSG00000100342,ENSG00000155368,ENSG00000100299,ENSG00000049449,ENSG00000166035,ENSG00000127022,ENSG00000090520,ENSG00000049239,ENSG00000140284,ENSG00000006756,ENSG00000155660,ENSG00000160404,ENSG00000166794 |
| GO:0005615 | extracellular space | 0.0033595 | 3543 | 739 | 177 | 0.2395129 | 0.0499577 | GO:CC | ENSG00000137441,ENSG00000004468,ENSG00000150687,ENSG00000196126,ENSG00000092010,ENSG00000072110,ENSG00000108679,ENSG00000179218,ENSG00000115523,ENSG00000159674,ENSG00000080573,ENSG00000155657,ENSG00000097021,ENSG00000182054,ENSG00000019582,ENSG00000142669,ENSG00000117560,ENSG00000203747,ENSG00000130164,ENSG00000143870,ENSG00000186469,ENSG00000069702,ENSG00000100911,ENSG00000205336,ENSG00000164111,ENSG00000177156,ENSG00000170315,ENSG00000125868,ENSG00000117632,ENSG00000167004,ENSG00000196924,ENSG00000146674,ENSG00000065911,ENSG00000120057,ENSG00000117984,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000172331,ENSG00000173114,ENSG00000172757,ENSG00000111537,ENSG00000111885,ENSG00000112139,ENSG00000232810,ENSG00000183691,ENSG00000134308,ENSG00000111640,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000103769,ENSG00000100380,ENSG00000108518,ENSG00000131171,ENSG00000005844,ENSG00000130592,ENSG00000116288,ENSG00000196230,ENSG00000134765,ENSG00000122121,ENSG00000073008,ENSG00000075234,ENSG00000175793,ENSG00000103966,ENSG00000137563,ENSG00000204264,ENSG00000077984,ENSG00000114978,ENSG00000187446,ENSG00000130402,ENSG00000170312,ENSG00000163359,ENSG00000117394,ENSG00000135069,ENSG00000242372,ENSG00000124299,ENSG00000065135,ENSG00000104687,ENSG00000213281,ENSG00000123131,ENSG00000041353,ENSG00000163041,ENSG00000044574,ENSG00000130741,ENSG00000072958,ENSG00000173786,ENSG00000166710,ENSG00000111229,ENSG00000104805,ENSG00000147065,ENSG00000129422,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000107317,ENSG00000111348,ENSG00000100342,ENSG00000156234,ENSG00000021355,ENSG00000101444,ENSG00000111331,ENSG00000074800,ENSG00000084623,ENSG00000105220,ENSG00000181467,ENSG00000071994,ENSG00000155368,ENSG00000100299,ENSG00000013725,ENSG00000163131,ENSG00000067560,ENSG00000064886,ENSG00000213719,ENSG00000213064,ENSG00000134202,ENSG00000133026,ENSG00000174684,ENSG00000204642,ENSG00000143727,ENSG00000006625,ENSG00000168961,ENSG00000115339,ENSG00000115902,ENSG00000172270,ENSG00000148175,ENSG00000204592,ENSG00000083444,ENSG00000002549,ENSG00000130812,ENSG00000153310,ENSG00000178996,ENSG00000070831,ENSG00000079691,ENSG00000101079,ENSG00000171302,ENSG00000166035,ENSG00000197043,ENSG00000132670,ENSG00000075624,ENSG00000075239,ENSG00000136824,ENSG00000165527,ENSG00000105612,ENSG00000105697,ENSG00000127022,ENSG00000197956,ENSG00000121579,ENSG00000055163,ENSG00000132386,ENSG00000123338,ENSG00000126432,ENSG00000196834,ENSG00000172531,ENSG00000140284,ENSG00000041357,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000092841,ENSG00000213366,ENSG00000127951,ENSG00000155660,ENSG00000131019,ENSG00000197409,ENSG00000137312,ENSG00000196839,ENSG00000132388,ENSG00000143321,ENSG00000148218,ENSG00000103489,ENSG00000011007,ENSG00000169223,ENSG00000140575,ENSG00000111450,ENSG00000113387,ENSG00000166794 |
| GO:0031300 | intrinsic component of organelle membrane | 0.0038717 | 400 | 739 | 31 | 0.0419486 | 0.0775000 | GO:CC | ENSG00000204267,ENSG00000196126,ENSG00000100321,ENSG00000179218,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000167004,ENSG00000110090,ENSG00000099194,ENSG00000171603,ENSG00000041353,ENSG00000044574,ENSG00000166710,ENSG00000183172,ENSG00000174684,ENSG00000204642,ENSG00000204592,ENSG00000176641,ENSG00000127022,ENSG00000127774,ENSG00000134049,ENSG00000124155,ENSG00000144043,ENSG00000175283,ENSG00000129968,ENSG00000140284,ENSG00000177076,ENSG00000078124 |
| GO:0055038 | recycling endosome membrane | 0.0045538 | 81 | 739 | 11 | 0.0148850 | 0.1358025 | GO:CC | ENSG00000167004,ENSG00000167461,ENSG00000125249,ENSG00000103769,ENSG00000103966,ENSG00000166710,ENSG00000181467,ENSG00000204642,ENSG00000204592,ENSG00000165527,ENSG00000129968 |
| GO:0030139 | endocytic vesicle | 0.0045538 | 298 | 739 | 25 | 0.0338295 | 0.0838926 | GO:CC | ENSG00000204267,ENSG00000196126,ENSG00000163599,ENSG00000179218,ENSG00000115523,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000151502,ENSG00000130164,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000167004,ENSG00000167461,ENSG00000103769,ENSG00000171130,ENSG00000166710,ENSG00000126016,ENSG00000166598,ENSG00000204642,ENSG00000204592,ENSG00000042753,ENSG00000070831,ENSG00000165527 |
| GO:0031301 | integral component of organelle membrane | 0.0045798 | 369 | 739 | 29 | 0.0392422 | 0.0785908 | GO:CC | ENSG00000204267,ENSG00000196126,ENSG00000100321,ENSG00000179218,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000223865,ENSG00000231389,ENSG00000167004,ENSG00000110090,ENSG00000099194,ENSG00000171603,ENSG00000044574,ENSG00000166710,ENSG00000183172,ENSG00000174684,ENSG00000204642,ENSG00000204592,ENSG00000176641,ENSG00000127022,ENSG00000127774,ENSG00000134049,ENSG00000124155,ENSG00000144043,ENSG00000175283,ENSG00000140284,ENSG00000177076,ENSG00000078124 |
| GO:0034663 | endoplasmic reticulum chaperone complex | 0.0055963 | 10 | 739 | 4 | 0.0054127 | 0.4000000 | GO:CC | ENSG00000143870,ENSG00000044574,ENSG00000166598,ENSG00000166794 |
| GO:0000323 | lytic vacuole | 0.0055963 | 697 | 739 | 46 | 0.0622463 | 0.0659971 | GO:CC | ENSG00000113721,ENSG00000196126,ENSG00000100321,ENSG00000115523,ENSG00000100427,ENSG00000163840,ENSG00000196735,ENSG00000019582,ENSG00000117560,ENSG00000130164,ENSG00000223865,ENSG00000231389,ENSG00000142089,ENSG00000169252,ENSG00000117984,ENSG00000103148,ENSG00000137474,ENSG00000196230,ENSG00000180644,ENSG00000137563,ENSG00000077984,ENSG00000215305,ENSG00000065135,ENSG00000072958,ENSG00000138071,ENSG00000131236,ENSG00000100299,ENSG00000163131,ENSG00000172794,ENSG00000204642,ENSG00000148175,ENSG00000042753,ENSG00000197043,ENSG00000113369,ENSG00000176641,ENSG00000105612,ENSG00000139370,ENSG00000109084,ENSG00000196072,ENSG00000010270,ENSG00000142867,ENSG00000006756,ENSG00000254087,ENSG00000137312,ENSG00000196839,ENSG00000242574 |
| GO:0005764 | lysosome | 0.0055963 | 697 | 739 | 46 | 0.0622463 | 0.0659971 | GO:CC | ENSG00000113721,ENSG00000196126,ENSG00000100321,ENSG00000115523,ENSG00000100427,ENSG00000163840,ENSG00000196735,ENSG00000019582,ENSG00000117560,ENSG00000130164,ENSG00000223865,ENSG00000231389,ENSG00000142089,ENSG00000169252,ENSG00000117984,ENSG00000103148,ENSG00000137474,ENSG00000196230,ENSG00000180644,ENSG00000137563,ENSG00000077984,ENSG00000215305,ENSG00000065135,ENSG00000072958,ENSG00000138071,ENSG00000131236,ENSG00000100299,ENSG00000163131,ENSG00000172794,ENSG00000204642,ENSG00000148175,ENSG00000042753,ENSG00000197043,ENSG00000113369,ENSG00000176641,ENSG00000105612,ENSG00000139370,ENSG00000109084,ENSG00000196072,ENSG00000010270,ENSG00000142867,ENSG00000006756,ENSG00000254087,ENSG00000137312,ENSG00000196839,ENSG00000242574 |
| GO:0005773 | vacuole | 0.0055963 | 797 | 739 | 51 | 0.0690122 | 0.0639900 | GO:CC | ENSG00000113721,ENSG00000196126,ENSG00000100321,ENSG00000115523,ENSG00000100427,ENSG00000163840,ENSG00000196735,ENSG00000019582,ENSG00000117560,ENSG00000130164,ENSG00000223865,ENSG00000231389,ENSG00000142089,ENSG00000169252,ENSG00000117984,ENSG00000149328,ENSG00000103148,ENSG00000137474,ENSG00000196230,ENSG00000180644,ENSG00000137563,ENSG00000077984,ENSG00000136436,ENSG00000215305,ENSG00000065135,ENSG00000072958,ENSG00000138071,ENSG00000131236,ENSG00000100299,ENSG00000163131,ENSG00000172794,ENSG00000204642,ENSG00000148175,ENSG00000042753,ENSG00000070831,ENSG00000118705,ENSG00000197043,ENSG00000113369,ENSG00000176641,ENSG00000105612,ENSG00000127666,ENSG00000139370,ENSG00000109084,ENSG00000196072,ENSG00000010270,ENSG00000142867,ENSG00000006756,ENSG00000254087,ENSG00000137312,ENSG00000196839,ENSG00000242574 |
| GO:0098636 | protein complex involved in cell adhesion | 0.0057212 | 36 | 739 | 7 | 0.0094723 | 0.1944444 | GO:CC | ENSG00000156886,ENSG00000163599,ENSG00000150093,ENSG00000139626,ENSG00000005844,ENSG00000254087,ENSG00000160255 |
| GO:0043233 | organelle lumen | 0.0061108 | 5898 | 739 | 273 | 0.3694181 | 0.0462869 | GO:CC | ENSG00000150687,ENSG00000148773,ENSG00000164308,ENSG00000152217,ENSG00000156587,ENSG00000138496,ENSG00000204267,ENSG00000113721,ENSG00000092010,ENSG00000072110,ENSG00000132530,ENSG00000117724,ENSG00000125347,ENSG00000108679,ENSG00000179218,ENSG00000115523,ENSG00000184357,ENSG00000135077,ENSG00000090857,ENSG00000165891,ENSG00000080573,ENSG00000155657,ENSG00000163840,ENSG00000097021,ENSG00000182054,ENSG00000123485,ENSG00000019582,ENSG00000142669,ENSG00000117560,ENSG00000144354,ENSG00000072135,ENSG00000164649,ENSG00000159216,ENSG00000115415,ENSG00000143870,ENSG00000100911,ENSG00000124191,ENSG00000113368,ENSG00000101057,ENSG00000163029,ENSG00000170315,ENSG00000166503,ENSG00000156970,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000112029,ENSG00000065911,ENSG00000117984,ENSG00000127947,ENSG00000123609,ENSG00000165512,ENSG00000077312,ENSG00000165617,ENSG00000111206,ENSG00000172757,ENSG00000138795,ENSG00000102554,ENSG00000179051,ENSG00000189430,ENSG00000099194,ENSG00000176890,ENSG00000100749,ENSG00000108179,ENSG00000118777,ENSG00000183734,ENSG00000132646,ENSG00000183741,ENSG00000167123,ENSG00000116288,ENSG00000196230,ENSG00000180644,ENSG00000111602,ENSG00000103202,ENSG00000135114,ENSG00000134321,ENSG00000124575,ENSG00000023572,ENSG00000100918,ENSG00000156463,ENSG00000137563,ENSG00000138642,ENSG00000204264,ENSG00000173821,ENSG00000105011,ENSG00000051341,ENSG00000131018,ENSG00000196976,ENSG00000114978,ENSG00000130402,ENSG00000188312,ENSG00000011426,ENSG00000170312,ENSG00000155846,ENSG00000163359,ENSG00000185651,ENSG00000164830,ENSG00000131944,ENSG00000092853,ENSG00000242372,ENSG00000169230,ENSG00000104687,ENSG00000123131,ENSG00000122971,ENSG00000119335,ENSG00000148400,ENSG00000089127,ENSG00000152256,ENSG00000089685,ENSG00000189159,ENSG00000121297,ENSG00000163041,ENSG00000044574,ENSG00000133315,ENSG00000188612,ENSG00000181938,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000104805,ENSG00000179632,ENSG00000163545,ENSG00000166454,ENSG00000129422,ENSG00000166197,ENSG00000204822,ENSG00000126016,ENSG00000241258,ENSG00000131931,ENSG00000138071,ENSG00000100897,ENSG00000166598,ENSG00000131236,ENSG00000132661,ENSG00000100342,ENSG00000225921,ENSG00000112031,ENSG00000118971,ENSG00000129534,ENSG00000021355,ENSG00000177613,ENSG00000093009,ENSG00000111331,ENSG00000143476,ENSG00000122952,ENSG00000105220,ENSG00000143228,ENSG00000053254,ENSG00000155368,ENSG00000100299,ENSG00000134909,ENSG00000163131,ENSG00000011485,ENSG00000196436,ENSG00000132932,ENSG00000213928,ENSG00000125944,ENSG00000127952,ENSG00000183172,ENSG00000114166,ENSG00000049449,ENSG00000189283,ENSG00000113810,ENSG00000185507,ENSG00000100298,ENSG00000144597,ENSG00000204256,ENSG00000087302,ENSG00000122877,ENSG00000165283,ENSG00000172795,ENSG00000131747,ENSG00000171617,ENSG00000132963,ENSG00000162702,ENSG00000132792,ENSG00000103994,ENSG00000237190,ENSG00000174371,ENSG00000160877,ENSG00000002549,ENSG00000187608,ENSG00000139579,ENSG00000162676,ENSG00000106462,ENSG00000153310,ENSG00000104765,ENSG00000079691,ENSG00000112996,ENSG00000124920,ENSG00000170860,ENSG00000171169,ENSG00000243660,ENSG00000179583,ENSG00000171302,ENSG00000166035,ENSG00000141030,ENSG00000074071,ENSG00000197142,ENSG00000189266,ENSG00000075624,ENSG00000096968,ENSG00000075239,ENSG00000109674,ENSG00000136824,ENSG00000079999,ENSG00000162385,ENSG00000159111,ENSG00000223496,ENSG00000127022,ENSG00000184897,ENSG00000102931,ENSG00000116670,ENSG00000185880,ENSG00000090520,ENSG00000049239,ENSG00000109536,ENSG00000128272,ENSG00000148337,ENSG00000124688,ENSG00000111335,ENSG00000114126,ENSG00000126432,ENSG00000214022,ENSG00000198736,ENSG00000049541,ENSG00000104738,ENSG00000119318,ENSG00000172531,ENSG00000178691,ENSG00000257390,ENSG00000153044,ENSG00000140284,ENSG00000137309,ENSG00000006756,ENSG00000041357,ENSG00000125870,ENSG00000254087,ENSG00000152601,ENSG00000189306,ENSG00000104472,ENSG00000140319,ENSG00000127951,ENSG00000155660,ENSG00000101082,ENSG00000164576,ENSG00000197409,ENSG00000172667,ENSG00000196839,ENSG00000143321,ENSG00000136104,ENSG00000155090,ENSG00000148218,ENSG00000134690,ENSG00000184575,ENSG00000177674,ENSG00000011007,ENSG00000178685,ENSG00000147889,ENSG00000137193,ENSG00000160404,ENSG00000169554,ENSG00000113387,ENSG00000166794,ENSG00000114631,ENSG00000111859,ENSG00000170485 |
| GO:0031974 | membrane-enclosed lumen | 0.0061108 | 5898 | 739 | 273 | 0.3694181 | 0.0462869 | GO:CC | ENSG00000150687,ENSG00000148773,ENSG00000164308,ENSG00000152217,ENSG00000156587,ENSG00000138496,ENSG00000204267,ENSG00000113721,ENSG00000092010,ENSG00000072110,ENSG00000132530,ENSG00000117724,ENSG00000125347,ENSG00000108679,ENSG00000179218,ENSG00000115523,ENSG00000184357,ENSG00000135077,ENSG00000090857,ENSG00000165891,ENSG00000080573,ENSG00000155657,ENSG00000163840,ENSG00000097021,ENSG00000182054,ENSG00000123485,ENSG00000019582,ENSG00000142669,ENSG00000117560,ENSG00000144354,ENSG00000072135,ENSG00000164649,ENSG00000159216,ENSG00000115415,ENSG00000143870,ENSG00000100911,ENSG00000124191,ENSG00000113368,ENSG00000101057,ENSG00000163029,ENSG00000170315,ENSG00000166503,ENSG00000156970,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000112029,ENSG00000065911,ENSG00000117984,ENSG00000127947,ENSG00000123609,ENSG00000165512,ENSG00000077312,ENSG00000165617,ENSG00000111206,ENSG00000172757,ENSG00000138795,ENSG00000102554,ENSG00000179051,ENSG00000189430,ENSG00000099194,ENSG00000176890,ENSG00000100749,ENSG00000108179,ENSG00000118777,ENSG00000183734,ENSG00000132646,ENSG00000183741,ENSG00000167123,ENSG00000116288,ENSG00000196230,ENSG00000180644,ENSG00000111602,ENSG00000103202,ENSG00000135114,ENSG00000134321,ENSG00000124575,ENSG00000023572,ENSG00000100918,ENSG00000156463,ENSG00000137563,ENSG00000138642,ENSG00000204264,ENSG00000173821,ENSG00000105011,ENSG00000051341,ENSG00000131018,ENSG00000196976,ENSG00000114978,ENSG00000130402,ENSG00000188312,ENSG00000011426,ENSG00000170312,ENSG00000155846,ENSG00000163359,ENSG00000185651,ENSG00000164830,ENSG00000131944,ENSG00000092853,ENSG00000242372,ENSG00000169230,ENSG00000104687,ENSG00000123131,ENSG00000122971,ENSG00000119335,ENSG00000148400,ENSG00000089127,ENSG00000152256,ENSG00000089685,ENSG00000189159,ENSG00000121297,ENSG00000163041,ENSG00000044574,ENSG00000133315,ENSG00000188612,ENSG00000181938,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000104805,ENSG00000179632,ENSG00000163545,ENSG00000166454,ENSG00000129422,ENSG00000166197,ENSG00000204822,ENSG00000126016,ENSG00000241258,ENSG00000131931,ENSG00000138071,ENSG00000100897,ENSG00000166598,ENSG00000131236,ENSG00000132661,ENSG00000100342,ENSG00000225921,ENSG00000112031,ENSG00000118971,ENSG00000129534,ENSG00000021355,ENSG00000177613,ENSG00000093009,ENSG00000111331,ENSG00000143476,ENSG00000122952,ENSG00000105220,ENSG00000143228,ENSG00000053254,ENSG00000155368,ENSG00000100299,ENSG00000134909,ENSG00000163131,ENSG00000011485,ENSG00000196436,ENSG00000132932,ENSG00000213928,ENSG00000125944,ENSG00000127952,ENSG00000183172,ENSG00000114166,ENSG00000049449,ENSG00000189283,ENSG00000113810,ENSG00000185507,ENSG00000100298,ENSG00000144597,ENSG00000204256,ENSG00000087302,ENSG00000122877,ENSG00000165283,ENSG00000172795,ENSG00000131747,ENSG00000171617,ENSG00000132963,ENSG00000162702,ENSG00000132792,ENSG00000103994,ENSG00000237190,ENSG00000174371,ENSG00000160877,ENSG00000002549,ENSG00000187608,ENSG00000139579,ENSG00000162676,ENSG00000106462,ENSG00000153310,ENSG00000104765,ENSG00000079691,ENSG00000112996,ENSG00000124920,ENSG00000170860,ENSG00000171169,ENSG00000243660,ENSG00000179583,ENSG00000171302,ENSG00000166035,ENSG00000141030,ENSG00000074071,ENSG00000197142,ENSG00000189266,ENSG00000075624,ENSG00000096968,ENSG00000075239,ENSG00000109674,ENSG00000136824,ENSG00000079999,ENSG00000162385,ENSG00000159111,ENSG00000223496,ENSG00000127022,ENSG00000184897,ENSG00000102931,ENSG00000116670,ENSG00000185880,ENSG00000090520,ENSG00000049239,ENSG00000109536,ENSG00000128272,ENSG00000148337,ENSG00000124688,ENSG00000111335,ENSG00000114126,ENSG00000126432,ENSG00000214022,ENSG00000198736,ENSG00000049541,ENSG00000104738,ENSG00000119318,ENSG00000172531,ENSG00000178691,ENSG00000257390,ENSG00000153044,ENSG00000140284,ENSG00000137309,ENSG00000006756,ENSG00000041357,ENSG00000125870,ENSG00000254087,ENSG00000152601,ENSG00000189306,ENSG00000104472,ENSG00000140319,ENSG00000127951,ENSG00000155660,ENSG00000101082,ENSG00000164576,ENSG00000197409,ENSG00000172667,ENSG00000196839,ENSG00000143321,ENSG00000136104,ENSG00000155090,ENSG00000148218,ENSG00000134690,ENSG00000184575,ENSG00000177674,ENSG00000011007,ENSG00000178685,ENSG00000147889,ENSG00000137193,ENSG00000160404,ENSG00000169554,ENSG00000113387,ENSG00000166794,ENSG00000114631,ENSG00000111859,ENSG00000170485 |
| GO:0070013 | intracellular organelle lumen | 0.0061108 | 5898 | 739 | 273 | 0.3694181 | 0.0462869 | GO:CC | ENSG00000150687,ENSG00000148773,ENSG00000164308,ENSG00000152217,ENSG00000156587,ENSG00000138496,ENSG00000204267,ENSG00000113721,ENSG00000092010,ENSG00000072110,ENSG00000132530,ENSG00000117724,ENSG00000125347,ENSG00000108679,ENSG00000179218,ENSG00000115523,ENSG00000184357,ENSG00000135077,ENSG00000090857,ENSG00000165891,ENSG00000080573,ENSG00000155657,ENSG00000163840,ENSG00000097021,ENSG00000182054,ENSG00000123485,ENSG00000019582,ENSG00000142669,ENSG00000117560,ENSG00000144354,ENSG00000072135,ENSG00000164649,ENSG00000159216,ENSG00000115415,ENSG00000143870,ENSG00000100911,ENSG00000124191,ENSG00000113368,ENSG00000101057,ENSG00000163029,ENSG00000170315,ENSG00000166503,ENSG00000156970,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000112029,ENSG00000065911,ENSG00000117984,ENSG00000127947,ENSG00000123609,ENSG00000165512,ENSG00000077312,ENSG00000165617,ENSG00000111206,ENSG00000172757,ENSG00000138795,ENSG00000102554,ENSG00000179051,ENSG00000189430,ENSG00000099194,ENSG00000176890,ENSG00000100749,ENSG00000108179,ENSG00000118777,ENSG00000183734,ENSG00000132646,ENSG00000183741,ENSG00000167123,ENSG00000116288,ENSG00000196230,ENSG00000180644,ENSG00000111602,ENSG00000103202,ENSG00000135114,ENSG00000134321,ENSG00000124575,ENSG00000023572,ENSG00000100918,ENSG00000156463,ENSG00000137563,ENSG00000138642,ENSG00000204264,ENSG00000173821,ENSG00000105011,ENSG00000051341,ENSG00000131018,ENSG00000196976,ENSG00000114978,ENSG00000130402,ENSG00000188312,ENSG00000011426,ENSG00000170312,ENSG00000155846,ENSG00000163359,ENSG00000185651,ENSG00000164830,ENSG00000131944,ENSG00000092853,ENSG00000242372,ENSG00000169230,ENSG00000104687,ENSG00000123131,ENSG00000122971,ENSG00000119335,ENSG00000148400,ENSG00000089127,ENSG00000152256,ENSG00000089685,ENSG00000189159,ENSG00000121297,ENSG00000163041,ENSG00000044574,ENSG00000133315,ENSG00000188612,ENSG00000181938,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000104805,ENSG00000179632,ENSG00000163545,ENSG00000166454,ENSG00000129422,ENSG00000166197,ENSG00000204822,ENSG00000126016,ENSG00000241258,ENSG00000131931,ENSG00000138071,ENSG00000100897,ENSG00000166598,ENSG00000131236,ENSG00000132661,ENSG00000100342,ENSG00000225921,ENSG00000112031,ENSG00000118971,ENSG00000129534,ENSG00000021355,ENSG00000177613,ENSG00000093009,ENSG00000111331,ENSG00000143476,ENSG00000122952,ENSG00000105220,ENSG00000143228,ENSG00000053254,ENSG00000155368,ENSG00000100299,ENSG00000134909,ENSG00000163131,ENSG00000011485,ENSG00000196436,ENSG00000132932,ENSG00000213928,ENSG00000125944,ENSG00000127952,ENSG00000183172,ENSG00000114166,ENSG00000049449,ENSG00000189283,ENSG00000113810,ENSG00000185507,ENSG00000100298,ENSG00000144597,ENSG00000204256,ENSG00000087302,ENSG00000122877,ENSG00000165283,ENSG00000172795,ENSG00000131747,ENSG00000171617,ENSG00000132963,ENSG00000162702,ENSG00000132792,ENSG00000103994,ENSG00000237190,ENSG00000174371,ENSG00000160877,ENSG00000002549,ENSG00000187608,ENSG00000139579,ENSG00000162676,ENSG00000106462,ENSG00000153310,ENSG00000104765,ENSG00000079691,ENSG00000112996,ENSG00000124920,ENSG00000170860,ENSG00000171169,ENSG00000243660,ENSG00000179583,ENSG00000171302,ENSG00000166035,ENSG00000141030,ENSG00000074071,ENSG00000197142,ENSG00000189266,ENSG00000075624,ENSG00000096968,ENSG00000075239,ENSG00000109674,ENSG00000136824,ENSG00000079999,ENSG00000162385,ENSG00000159111,ENSG00000223496,ENSG00000127022,ENSG00000184897,ENSG00000102931,ENSG00000116670,ENSG00000185880,ENSG00000090520,ENSG00000049239,ENSG00000109536,ENSG00000128272,ENSG00000148337,ENSG00000124688,ENSG00000111335,ENSG00000114126,ENSG00000126432,ENSG00000214022,ENSG00000198736,ENSG00000049541,ENSG00000104738,ENSG00000119318,ENSG00000172531,ENSG00000178691,ENSG00000257390,ENSG00000153044,ENSG00000140284,ENSG00000137309,ENSG00000006756,ENSG00000041357,ENSG00000125870,ENSG00000254087,ENSG00000152601,ENSG00000189306,ENSG00000104472,ENSG00000140319,ENSG00000127951,ENSG00000155660,ENSG00000101082,ENSG00000164576,ENSG00000197409,ENSG00000172667,ENSG00000196839,ENSG00000143321,ENSG00000136104,ENSG00000155090,ENSG00000148218,ENSG00000134690,ENSG00000184575,ENSG00000177674,ENSG00000011007,ENSG00000178685,ENSG00000147889,ENSG00000137193,ENSG00000160404,ENSG00000169554,ENSG00000113387,ENSG00000166794,ENSG00000114631,ENSG00000111859,ENSG00000170485 |
| GO:0030669 | clathrin-coated endocytic vesicle membrane | 0.0064414 | 37 | 739 | 7 | 0.0094723 | 0.1891892 | GO:CC | ENSG00000196126,ENSG00000196735,ENSG00000019582,ENSG00000130164,ENSG00000223865,ENSG00000231389,ENSG00000042753 |
| GO:0030666 | endocytic vesicle membrane | 0.0065423 | 159 | 739 | 16 | 0.0216509 | 0.1006289 | GO:CC | ENSG00000204267,ENSG00000196126,ENSG00000179218,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000130164,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000167461,ENSG00000171130,ENSG00000166710,ENSG00000204642,ENSG00000204592,ENSG00000042753 |
| GO:0043228 | non-membrane-bounded organelle | 0.0067802 | 4964 | 739 | 234 | 0.3166441 | 0.0471394 | GO:CC | ENSG00000196169,ENSG00000148773,ENSG00000138496,ENSG00000183688,ENSG00000229474,ENSG00000248905,ENSG00000072110,ENSG00000129595,ENSG00000117724,ENSG00000125347,ENSG00000157423,ENSG00000163492,ENSG00000002834,ENSG00000184357,ENSG00000165891,ENSG00000155657,ENSG00000123485,ENSG00000164649,ENSG00000159216,ENSG00000160014,ENSG00000034510,ENSG00000115415,ENSG00000113368,ENSG00000101057,ENSG00000163029,ENSG00000156970,ENSG00000125868,ENSG00000105639,ENSG00000125864,ENSG00000117632,ENSG00000196924,ENSG00000137265,ENSG00000118193,ENSG00000112029,ENSG00000127947,ENSG00000136167,ENSG00000121039,ENSG00000167461,ENSG00000138160,ENSG00000111206,ENSG00000172757,ENSG00000102554,ENSG00000179051,ENSG00000189430,ENSG00000099194,ENSG00000117228,ENSG00000138180,ENSG00000126787,ENSG00000176890,ENSG00000133739,ENSG00000100749,ENSG00000111640,ENSG00000183734,ENSG00000132646,ENSG00000103769,ENSG00000108518,ENSG00000183741,ENSG00000130592,ENSG00000137474,ENSG00000116288,ENSG00000196230,ENSG00000111602,ENSG00000135114,ENSG00000134321,ENSG00000124575,ENSG00000100918,ENSG00000143543,ENSG00000173821,ENSG00000105011,ENSG00000051341,ENSG00000131018,ENSG00000114978,ENSG00000187446,ENSG00000130402,ENSG00000188312,ENSG00000011426,ENSG00000170312,ENSG00000105887,ENSG00000136436,ENSG00000164830,ENSG00000117394,ENSG00000152969,ENSG00000055332,ENSG00000239713,ENSG00000242372,ENSG00000123416,ENSG00000152229,ENSG00000065135,ENSG00000122971,ENSG00000119335,ENSG00000157601,ENSG00000152256,ENSG00000204472,ENSG00000089685,ENSG00000189159,ENSG00000121297,ENSG00000163041,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000111229,ENSG00000179632,ENSG00000152778,ENSG00000147065,ENSG00000166974,ENSG00000204899,ENSG00000129422,ENSG00000166197,ENSG00000204822,ENSG00000126016,ENSG00000073910,ENSG00000131931,ENSG00000138071,ENSG00000131236,ENSG00000111348,ENSG00000225921,ENSG00000118971,ENSG00000129534,ENSG00000021355,ENSG00000093009,ENSG00000185650,ENSG00000074800,ENSG00000143476,ENSG00000122952,ENSG00000143228,ENSG00000172164,ENSG00000053254,ENSG00000136717,ENSG00000134909,ENSG00000131504,ENSG00000067560,ENSG00000154027,ENSG00000213928,ENSG00000114166,ENSG00000189283,ENSG00000075340,ENSG00000133026,ENSG00000113810,ENSG00000185507,ENSG00000100298,ENSG00000087302,ENSG00000151466,ENSG00000115902,ENSG00000122877,ENSG00000165283,ENSG00000173517,ENSG00000172795,ENSG00000148175,ENSG00000131747,ENSG00000171617,ENSG00000132792,ENSG00000103994,ENSG00000158321,ENSG00000237190,ENSG00000139579,ENSG00000106462,ENSG00000176101,ENSG00000070831,ENSG00000152253,ENSG00000079691,ENSG00000112996,ENSG00000170860,ENSG00000151239,ENSG00000243660,ENSG00000153790,ENSG00000074071,ENSG00000147234,ENSG00000197142,ENSG00000189266,ENSG00000066279,ENSG00000075624,ENSG00000096968,ENSG00000128394,ENSG00000136824,ENSG00000079999,ENSG00000117155,ENSG00000159111,ENSG00000223496,ENSG00000127022,ENSG00000109805,ENSG00000196072,ENSG00000184897,ENSG00000102931,ENSG00000116670,ENSG00000072571,ENSG00000184640,ENSG00000109536,ENSG00000128272,ENSG00000124688,ENSG00000142867,ENSG00000114126,ENSG00000214022,ENSG00000146112,ENSG00000198736,ENSG00000049541,ENSG00000104738,ENSG00000172531,ENSG00000178691,ENSG00000257390,ENSG00000153044,ENSG00000137309,ENSG00000132321,ENSG00000041357,ENSG00000125354,ENSG00000125870,ENSG00000254087,ENSG00000152601,ENSG00000189306,ENSG00000104472,ENSG00000092841,ENSG00000182628,ENSG00000164576,ENSG00000197409,ENSG00000172667,ENSG00000137312,ENSG00000155090,ENSG00000134690,ENSG00000011007,ENSG00000160753,ENSG00000178685,ENSG00000132256,ENSG00000147889,ENSG00000139926,ENSG00000140575,ENSG00000137193,ENSG00000175104,ENSG00000196642,ENSG00000169554,ENSG00000127084,ENSG00000113387,ENSG00000111859,ENSG00000170485 |
| GO:0016020 | membrane | 0.0071346 | 9731 | 739 | 425 | 0.5751015 | 0.0436749 | GO:CC | ENSG00000172057,ENSG00000134824,ENSG00000100453,ENSG00000004468,ENSG00000148773,ENSG00000164308,ENSG00000179344,ENSG00000100450,ENSG00000138496,ENSG00000204267,ENSG00000113721,ENSG00000142634,ENSG00000211805,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000248905,ENSG00000072110,ENSG00000073605,ENSG00000156886,ENSG00000163599,ENSG00000105374,ENSG00000221963,ENSG00000108679,ENSG00000100321,ENSG00000180739,ENSG00000109956,ENSG00000179218,ENSG00000211815,ENSG00000126709,ENSG00000175274,ENSG00000135077,ENSG00000092068,ENSG00000160932,ENSG00000147459,ENSG00000154451,ENSG00000162654,ENSG00000100427,ENSG00000162073,ENSG00000163840,ENSG00000057704,ENSG00000089692,ENSG00000181036,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000117560,ENSG00000198513,ENSG00000164649,ENSG00000203747,ENSG00000151502,ENSG00000160014,ENSG00000173482,ENSG00000130164,ENSG00000143870,ENSG00000155629,ENSG00000186469,ENSG00000069702,ENSG00000091129,ENSG00000100911,ENSG00000130511,ENSG00000221866,ENSG00000205336,ENSG00000164111,ENSG00000113368,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000125864,ENSG00000117632,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000169442,ENSG00000118193,ENSG00000120057,ENSG00000117984,ENSG00000186470,ENSG00000150093,ENSG00000136167,ENSG00000211746,ENSG00000121039,ENSG00000167461,ENSG00000105409,ENSG00000158966,ENSG00000138160,ENSG00000096996,ENSG00000125249,ENSG00000173114,ENSG00000211698,ENSG00000133321,ENSG00000172757,ENSG00000211745,ENSG00000110090,ENSG00000111885,ENSG00000179051,ENSG00000123179,ENSG00000112139,ENSG00000189430,ENSG00000099194,ENSG00000232810,ENSG00000211786,ENSG00000134539,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000171202,ENSG00000176890,ENSG00000211721,ENSG00000100749,ENSG00000108179,ENSG00000111640,ENSG00000118777,ENSG00000172292,ENSG00000134352,ENSG00000139626,ENSG00000167914,ENSG00000153563,ENSG00000103769,ENSG00000108518,ENSG00000128335,ENSG00000117226,ENSG00000128284,ENSG00000005844,ENSG00000130592,ENSG00000103148,ENSG00000211747,ENSG00000084092,ENSG00000185201,ENSG00000167123,ENSG00000137474,ENSG00000116288,ENSG00000196230,ENSG00000134765,ENSG00000103512,ENSG00000171596,ENSG00000180644,ENSG00000103202,ENSG00000106868,ENSG00000122121,ENSG00000073008,ENSG00000213390,ENSG00000135114,ENSG00000134321,ENSG00000249437,ENSG00000169855,ENSG00000103966,ENSG00000152465,ENSG00000143543,ENSG00000106392,ENSG00000143742,ENSG00000131018,ENSG00000188191,ENSG00000237254,ENSG00000187446,ENSG00000071205,ENSG00000170312,ENSG00000170222,ENSG00000122223,ENSG00000136436,ENSG00000185885,ENSG00000163359,ENSG00000117394,ENSG00000172116,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000165949,ENSG00000152969,ENSG00000061337,ENSG00000215305,ENSG00000055332,ENSG00000153094,ENSG00000123416,ENSG00000152229,ENSG00000065135,ENSG00000213445,ENSG00000104687,ENSG00000213281,ENSG00000171451,ENSG00000164919,ENSG00000110080,ENSG00000148400,ENSG00000157601,ENSG00000041353,ENSG00000089127,ENSG00000167723,ENSG00000075420,ENSG00000204472,ENSG00000171130,ENSG00000184007,ENSG00000189159,ENSG00000121297,ENSG00000044574,ENSG00000124587,ENSG00000171246,ENSG00000116030,ENSG00000064666,ENSG00000233954,ENSG00000072958,ENSG00000173786,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000073803,ENSG00000159618,ENSG00000104805,ENSG00000179632,ENSG00000152778,ENSG00000163823,ENSG00000147065,ENSG00000129422,ENSG00000204822,ENSG00000126016,ENSG00000241258,ENSG00000206127,ENSG00000253626,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000110448,ENSG00000107317,ENSG00000111348,ENSG00000100342,ENSG00000108798,ENSG00000118971,ENSG00000084090,ENSG00000177150,ENSG00000021355,ENSG00000196954,ENSG00000115155,ENSG00000100605,ENSG00000111331,ENSG00000074800,ENSG00000143476,ENSG00000105220,ENSG00000143228,ENSG00000181467,ENSG00000158869,ENSG00000196449,ENSG00000172164,ENSG00000145649,ENSG00000136717,ENSG00000168421,ENSG00000100299,ENSG00000013725,ENSG00000134909,ENSG00000158006,ENSG00000170881,ENSG00000100385,ENSG00000139921,ENSG00000131504,ENSG00000184916,ENSG00000128039,ENSG00000198821,ENSG00000134490,ENSG00000011485,ENSG00000067560,ENSG00000205730,ENSG00000132932,ENSG00000183172,ENSG00000189283,ENSG00000213719,ENSG00000213064,ENSG00000165304,ENSG00000186648,ENSG00000172794,ENSG00000075340,ENSG00000133026,ENSG00000174684,ENSG00000115520,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000165548,ENSG00000143727,ENSG00000101474,ENSG00000151466,ENSG00000115339,ENSG00000211794,ENSG00000115902,ENSG00000158882,ENSG00000172270,ENSG00000165283,ENSG00000148175,ENSG00000141736,ENSG00000132963,ENSG00000204592,ENSG00000132182,ENSG00000132792,ENSG00000083444,ENSG00000103994,ENSG00000174371,ENSG00000157600,ENSG00000129625,ENSG00000166881,ENSG00000167286,ENSG00000157873,ENSG00000021762,ENSG00000082153,ENSG00000198843,ENSG00000111863,ENSG00000068489,ENSG00000042753,ENSG00000153310,ENSG00000178996,ENSG00000104765,ENSG00000070831,ENSG00000079691,ENSG00000172936,ENSG00000112996,ENSG00000124920,ENSG00000171169,ENSG00000151239,ENSG00000118705,ENSG00000128294,ENSG00000171302,ENSG00000204161,ENSG00000178719,ENSG00000074071,ENSG00000147234,ENSG00000197142,ENSG00000197043,ENSG00000132670,ENSG00000066279,ENSG00000075624,ENSG00000113369,ENSG00000151881,ENSG00000096968,ENSG00000176641,ENSG00000170837,ENSG00000165527,ENSG00000171954,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000159111,ENSG00000139370,ENSG00000109084,ENSG00000127022,ENSG00000197956,ENSG00000109805,ENSG00000026751,ENSG00000138018,ENSG00000148908,ENSG00000196072,ENSG00000138617,ENSG00000125648,ENSG00000184154,ENSG00000072571,ENSG00000055163,ENSG00000090520,ENSG00000256436,ENSG00000108932,ENSG00000127774,ENSG00000123338,ENSG00000010270,ENSG00000140450,ENSG00000128272,ENSG00000134049,ENSG00000148337,ENSG00000124688,ENSG00000142867,ENSG00000110852,ENSG00000111335,ENSG00000109390,ENSG00000143740,ENSG00000124155,ENSG00000145337,ENSG00000144043,ENSG00000175283,ENSG00000104738,ENSG00000172531,ENSG00000101084,ENSG00000129968,ENSG00000140284,ENSG00000006756,ENSG00000125354,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000143248,ENSG00000092841,ENSG00000263874,ENSG00000111796,ENSG00000183726,ENSG00000177076,ENSG00000101082,ENSG00000131019,ENSG00000197409,ENSG00000172667,ENSG00000150756,ENSG00000131873,ENSG00000173660,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000089693,ENSG00000242574,ENSG00000147168,ENSG00000177674,ENSG00000103489,ENSG00000135960,ENSG00000154518,ENSG00000028137,ENSG00000169223,ENSG00000111481,ENSG00000139926,ENSG00000140575,ENSG00000137193,ENSG00000146859,ENSG00000111450,ENSG00000175104,ENSG00000078124,ENSG00000110218,ENSG00000166794,ENSG00000114631,ENSG00000111859,ENSG00000112759,ENSG00000081985 |
| GO:0000139 | Golgi membrane | 0.0075576 | 752 | 739 | 48 | 0.0649526 | 0.0638298 | GO:CC | ENSG00000196126,ENSG00000109956,ENSG00000154451,ENSG00000162654,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000198513,ENSG00000223865,ENSG00000231389,ENSG00000167461,ENSG00000111885,ENSG00000117228,ENSG00000117226,ENSG00000106392,ENSG00000187446,ENSG00000117394,ENSG00000139182,ENSG00000171603,ENSG00000065135,ENSG00000213281,ENSG00000171451,ENSG00000110080,ENSG00000148400,ENSG00000072958,ENSG00000166710,ENSG00000104805,ENSG00000206127,ENSG00000115155,ENSG00000134909,ENSG00000174684,ENSG00000149294,ENSG00000204642,ENSG00000115339,ENSG00000172270,ENSG00000204592,ENSG00000070831,ENSG00000128294,ENSG00000171302,ENSG00000134049,ENSG00000144043,ENSG00000177076,ENSG00000131873,ENSG00000177674,ENSG00000103489,ENSG00000169223,ENSG00000111481,ENSG00000078124 |
| GO:0000932 | P-body | 0.0075576 | 88 | 739 | 11 | 0.0148850 | 0.1250000 | GO:CC | ENSG00000229474,ENSG00000131018,ENSG00000239713,ENSG00000185650,ENSG00000100298,ENSG00000172795,ENSG00000170860,ENSG00000189266,ENSG00000128394,ENSG00000041357,ENSG00000132256 |
| GO:0043232 | intracellular non-membrane-bounded organelle | 0.0076146 | 4954 | 739 | 233 | 0.3152909 | 0.0470327 | GO:CC | ENSG00000196169,ENSG00000148773,ENSG00000138496,ENSG00000183688,ENSG00000229474,ENSG00000248905,ENSG00000072110,ENSG00000129595,ENSG00000117724,ENSG00000125347,ENSG00000157423,ENSG00000163492,ENSG00000002834,ENSG00000184357,ENSG00000165891,ENSG00000155657,ENSG00000123485,ENSG00000164649,ENSG00000159216,ENSG00000160014,ENSG00000034510,ENSG00000115415,ENSG00000113368,ENSG00000101057,ENSG00000163029,ENSG00000156970,ENSG00000125868,ENSG00000105639,ENSG00000125864,ENSG00000117632,ENSG00000196924,ENSG00000137265,ENSG00000118193,ENSG00000112029,ENSG00000127947,ENSG00000136167,ENSG00000121039,ENSG00000167461,ENSG00000138160,ENSG00000111206,ENSG00000172757,ENSG00000102554,ENSG00000179051,ENSG00000189430,ENSG00000099194,ENSG00000117228,ENSG00000138180,ENSG00000126787,ENSG00000176890,ENSG00000133739,ENSG00000100749,ENSG00000111640,ENSG00000183734,ENSG00000132646,ENSG00000103769,ENSG00000108518,ENSG00000183741,ENSG00000130592,ENSG00000137474,ENSG00000116288,ENSG00000196230,ENSG00000111602,ENSG00000135114,ENSG00000134321,ENSG00000124575,ENSG00000100918,ENSG00000143543,ENSG00000173821,ENSG00000105011,ENSG00000051341,ENSG00000131018,ENSG00000114978,ENSG00000187446,ENSG00000130402,ENSG00000188312,ENSG00000011426,ENSG00000170312,ENSG00000105887,ENSG00000136436,ENSG00000164830,ENSG00000117394,ENSG00000152969,ENSG00000055332,ENSG00000239713,ENSG00000242372,ENSG00000123416,ENSG00000152229,ENSG00000065135,ENSG00000122971,ENSG00000119335,ENSG00000157601,ENSG00000152256,ENSG00000204472,ENSG00000089685,ENSG00000189159,ENSG00000121297,ENSG00000163041,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000111229,ENSG00000179632,ENSG00000152778,ENSG00000147065,ENSG00000166974,ENSG00000204899,ENSG00000129422,ENSG00000166197,ENSG00000204822,ENSG00000126016,ENSG00000073910,ENSG00000131931,ENSG00000138071,ENSG00000131236,ENSG00000111348,ENSG00000225921,ENSG00000118971,ENSG00000129534,ENSG00000021355,ENSG00000093009,ENSG00000185650,ENSG00000074800,ENSG00000143476,ENSG00000122952,ENSG00000143228,ENSG00000172164,ENSG00000053254,ENSG00000136717,ENSG00000134909,ENSG00000131504,ENSG00000067560,ENSG00000154027,ENSG00000213928,ENSG00000114166,ENSG00000189283,ENSG00000075340,ENSG00000133026,ENSG00000113810,ENSG00000185507,ENSG00000100298,ENSG00000087302,ENSG00000151466,ENSG00000115902,ENSG00000122877,ENSG00000165283,ENSG00000173517,ENSG00000172795,ENSG00000148175,ENSG00000131747,ENSG00000171617,ENSG00000132792,ENSG00000103994,ENSG00000158321,ENSG00000237190,ENSG00000139579,ENSG00000106462,ENSG00000176101,ENSG00000070831,ENSG00000152253,ENSG00000079691,ENSG00000112996,ENSG00000170860,ENSG00000151239,ENSG00000243660,ENSG00000153790,ENSG00000074071,ENSG00000147234,ENSG00000197142,ENSG00000189266,ENSG00000066279,ENSG00000075624,ENSG00000096968,ENSG00000128394,ENSG00000136824,ENSG00000079999,ENSG00000117155,ENSG00000159111,ENSG00000223496,ENSG00000127022,ENSG00000109805,ENSG00000196072,ENSG00000184897,ENSG00000102931,ENSG00000116670,ENSG00000072571,ENSG00000184640,ENSG00000109536,ENSG00000128272,ENSG00000124688,ENSG00000142867,ENSG00000114126,ENSG00000214022,ENSG00000146112,ENSG00000198736,ENSG00000049541,ENSG00000104738,ENSG00000172531,ENSG00000178691,ENSG00000257390,ENSG00000153044,ENSG00000137309,ENSG00000132321,ENSG00000041357,ENSG00000125354,ENSG00000125870,ENSG00000152601,ENSG00000189306,ENSG00000104472,ENSG00000092841,ENSG00000182628,ENSG00000164576,ENSG00000197409,ENSG00000172667,ENSG00000137312,ENSG00000155090,ENSG00000134690,ENSG00000011007,ENSG00000160753,ENSG00000178685,ENSG00000132256,ENSG00000147889,ENSG00000139926,ENSG00000140575,ENSG00000137193,ENSG00000175104,ENSG00000196642,ENSG00000169554,ENSG00000127084,ENSG00000113387,ENSG00000111859,ENSG00000170485 |
| GO:0071944 | cell periphery | 0.0076783 | 5732 | 739 | 265 | 0.3585927 | 0.0462317 | GO:CC | ENSG00000172057,ENSG00000134824,ENSG00000100453,ENSG00000004468,ENSG00000179344,ENSG00000113721,ENSG00000211805,ENSG00000117281,ENSG00000196126,ENSG00000007402,ENSG00000248905,ENSG00000072110,ENSG00000073605,ENSG00000156886,ENSG00000163599,ENSG00000105374,ENSG00000100321,ENSG00000180739,ENSG00000179218,ENSG00000211815,ENSG00000002834,ENSG00000126709,ENSG00000135077,ENSG00000092068,ENSG00000160932,ENSG00000147459,ENSG00000162654,ENSG00000100427,ENSG00000089692,ENSG00000181036,ENSG00000196735,ENSG00000019582,ENSG00000117560,ENSG00000203747,ENSG00000160014,ENSG00000173482,ENSG00000130164,ENSG00000143870,ENSG00000155629,ENSG00000186469,ENSG00000069702,ENSG00000091129,ENSG00000221866,ENSG00000205336,ENSG00000164111,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000125868,ENSG00000105639,ENSG00000125864,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000196924,ENSG00000169442,ENSG00000118193,ENSG00000186470,ENSG00000150093,ENSG00000136167,ENSG00000211746,ENSG00000167461,ENSG00000105409,ENSG00000158966,ENSG00000096996,ENSG00000125249,ENSG00000211698,ENSG00000172757,ENSG00000211745,ENSG00000179051,ENSG00000112139,ENSG00000189430,ENSG00000232810,ENSG00000211786,ENSG00000134539,ENSG00000117228,ENSG00000138180,ENSG00000211721,ENSG00000111640,ENSG00000118777,ENSG00000134352,ENSG00000139626,ENSG00000167914,ENSG00000153563,ENSG00000103769,ENSG00000108518,ENSG00000005844,ENSG00000130592,ENSG00000211747,ENSG00000185201,ENSG00000167123,ENSG00000137474,ENSG00000116288,ENSG00000134765,ENSG00000171596,ENSG00000180644,ENSG00000122121,ENSG00000073008,ENSG00000213390,ENSG00000249437,ENSG00000169855,ENSG00000103966,ENSG00000152465,ENSG00000143543,ENSG00000131018,ENSG00000188191,ENSG00000237254,ENSG00000187446,ENSG00000130402,ENSG00000011426,ENSG00000071205,ENSG00000122223,ENSG00000185885,ENSG00000163359,ENSG00000117394,ENSG00000172116,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000061337,ENSG00000152229,ENSG00000065135,ENSG00000104687,ENSG00000213281,ENSG00000148400,ENSG00000157601,ENSG00000041353,ENSG00000167723,ENSG00000204472,ENSG00000184007,ENSG00000121297,ENSG00000044574,ENSG00000171246,ENSG00000116030,ENSG00000072958,ENSG00000173786,ENSG00000166710,ENSG00000211810,ENSG00000159618,ENSG00000179632,ENSG00000152778,ENSG00000163823,ENSG00000147065,ENSG00000129422,ENSG00000126016,ENSG00000241258,ENSG00000073910,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000110448,ENSG00000196954,ENSG00000115155,ENSG00000100605,ENSG00000111331,ENSG00000074800,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000172164,ENSG00000145649,ENSG00000136717,ENSG00000168421,ENSG00000100299,ENSG00000013725,ENSG00000134909,ENSG00000100385,ENSG00000131504,ENSG00000184916,ENSG00000198821,ENSG00000011485,ENSG00000067560,ENSG00000132932,ENSG00000189283,ENSG00000213719,ENSG00000165304,ENSG00000186648,ENSG00000172794,ENSG00000075340,ENSG00000133026,ENSG00000149294,ENSG00000204642,ENSG00000165548,ENSG00000143727,ENSG00000211794,ENSG00000115902,ENSG00000172270,ENSG00000165283,ENSG00000148175,ENSG00000141736,ENSG00000204592,ENSG00000174371,ENSG00000167286,ENSG00000157873,ENSG00000111863,ENSG00000042753,ENSG00000178996,ENSG00000070831,ENSG00000079691,ENSG00000172936,ENSG00000171169,ENSG00000151239,ENSG00000171302,ENSG00000147234,ENSG00000197142,ENSG00000132670,ENSG00000066279,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000170837,ENSG00000165527,ENSG00000168329,ENSG00000162104,ENSG00000139370,ENSG00000109084,ENSG00000105697,ENSG00000127022,ENSG00000197956,ENSG00000026751,ENSG00000148908,ENSG00000184154,ENSG00000072571,ENSG00000184640,ENSG00000256436,ENSG00000108932,ENSG00000123338,ENSG00000140450,ENSG00000128272,ENSG00000148337,ENSG00000142867,ENSG00000110852,ENSG00000143740,ENSG00000172531,ENSG00000129968,ENSG00000140284,ENSG00000125354,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000143248,ENSG00000067840,ENSG00000111796,ENSG00000101082,ENSG00000131019,ENSG00000172667,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000242574,ENSG00000147168,ENSG00000177674,ENSG00000135960,ENSG00000028137,ENSG00000169223,ENSG00000139926,ENSG00000140575,ENSG00000137193,ENSG00000111450,ENSG00000175104,ENSG00000110218,ENSG00000114631,ENSG00000111859,ENSG00000112759,ENSG00000081985 |
| GO:0070820 | tertiary granule | 0.0078435 | 163 | 739 | 16 | 0.0216509 | 0.0981595 | GO:CC | ENSG00000117984,ENSG00000134765,ENSG00000137563,ENSG00000213281,ENSG00000064666,ENSG00000166710,ENSG00000181467,ENSG00000158869,ENSG00000163131,ENSG00000131504,ENSG00000067560,ENSG00000148175,ENSG00000171302,ENSG00000147234,ENSG00000123338,ENSG00000160255 |
| GO:0035770 | ribonucleoprotein granule | 0.0094978 | 232 | 739 | 20 | 0.0270636 | 0.0862069 | GO:CC | ENSG00000229474,ENSG00000196230,ENSG00000131018,ENSG00000239713,ENSG00000116030,ENSG00000021355,ENSG00000185650,ENSG00000100298,ENSG00000172795,ENSG00000070831,ENSG00000170860,ENSG00000189266,ENSG00000075624,ENSG00000128394,ENSG00000257390,ENSG00000041357,ENSG00000125870,ENSG00000152601,ENSG00000132256,ENSG00000140575 |
| GO:0005515 | protein binding | 0.0000004 | 12743 | 718 | 577 | 0.8036212 | 0.0452798 | GO:MF | ENSG00000172057,ENSG00000137441,ENSG00000100453,ENSG00000004468,ENSG00000196169,ENSG00000148773,ENSG00000179344,ENSG00000152217,ENSG00000156587,ENSG00000119922,ENSG00000138496,ENSG00000204267,ENSG00000113721,ENSG00000142634,ENSG00000117281,ENSG00000183688,ENSG00000229474,ENSG00000092010,ENSG00000248905,ENSG00000072110,ENSG00000129595,ENSG00000073861,ENSG00000163599,ENSG00000132530,ENSG00000117724,ENSG00000125347,ENSG00000105374,ENSG00000221963,ENSG00000108679,ENSG00000100321,ENSG00000179218,ENSG00000163492,ENSG00000002834,ENSG00000126709,ENSG00000159674,ENSG00000184357,ENSG00000135077,ENSG00000090857,ENSG00000092068,ENSG00000165891,ENSG00000147459,ENSG00000154451,ENSG00000162654,ENSG00000100427,ENSG00000080573,ENSG00000134184,ENSG00000155657,ENSG00000163840,ENSG00000057704,ENSG00000089692,ENSG00000181036,ENSG00000097021,ENSG00000196735,ENSG00000163421,ENSG00000123485,ENSG00000231925,ENSG00000019582,ENSG00000117560,ENSG00000198513,ENSG00000072135,ENSG00000164649,ENSG00000159216,ENSG00000151502,ENSG00000160014,ENSG00000034510,ENSG00000173482,ENSG00000130164,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000155629,ENSG00000186469,ENSG00000069702,ENSG00000091129,ENSG00000100911,ENSG00000130511,ENSG00000221866,ENSG00000205336,ENSG00000164111,ENSG00000113368,ENSG00000101057,ENSG00000177156,ENSG00000163029,ENSG00000170315,ENSG00000166503,ENSG00000156970,ENSG00000171848,ENSG00000125868,ENSG00000105639,ENSG00000125864,ENSG00000117632,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000175550,ENSG00000118193,ENSG00000112029,ENSG00000120057,ENSG00000117984,ENSG00000127947,ENSG00000186470,ENSG00000157216,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000105409,ENSG00000123609,ENSG00000173848,ENSG00000138160,ENSG00000096996,ENSG00000077312,ENSG00000165617,ENSG00000172331,ENSG00000125249,ENSG00000173114,ENSG00000111206,ENSG00000133321,ENSG00000172757,ENSG00000138795,ENSG00000110090,ENSG00000111537,ENSG00000102554,ENSG00000179051,ENSG00000112139,ENSG00000189430,ENSG00000099194,ENSG00000232810,ENSG00000183691,ENSG00000134539,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000126787,ENSG00000176890,ENSG00000204397,ENSG00000133739,ENSG00000100749,ENSG00000108179,ENSG00000111640,ENSG00000118777,ENSG00000183734,ENSG00000172292,ENSG00000134352,ENSG00000139626,ENSG00000132646,ENSG00000153563,ENSG00000103769,ENSG00000100380,ENSG00000108518,ENSG00000128335,ENSG00000117226,ENSG00000183741,ENSG00000131171,ENSG00000005844,ENSG00000130592,ENSG00000103148,ENSG00000084092,ENSG00000137474,ENSG00000116288,ENSG00000196230,ENSG00000180644,ENSG00000111602,ENSG00000103202,ENSG00000073008,ENSG00000075234,ENSG00000135114,ENSG00000134321,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000103966,ENSG00000100918,ENSG00000152465,ENSG00000156463,ENSG00000143543,ENSG00000106392,ENSG00000204264,ENSG00000143742,ENSG00000105011,ENSG00000051341,ENSG00000131018,ENSG00000205413,ENSG00000196976,ENSG00000188191,ENSG00000077984,ENSG00000114978,ENSG00000187446,ENSG00000130402,ENSG00000188312,ENSG00000011426,ENSG00000071205,ENSG00000170312,ENSG00000105887,ENSG00000167618,ENSG00000155846,ENSG00000122223,ENSG00000136436,ENSG00000197568,ENSG00000185885,ENSG00000163359,ENSG00000185651,ENSG00000117394,ENSG00000172116,ENSG00000131944,ENSG00000070018,ENSG00000171603,ENSG00000165949,ENSG00000185304,ENSG00000152969,ENSG00000092853,ENSG00000061337,ENSG00000215305,ENSG00000055332,ENSG00000239713,ENSG00000242372,ENSG00000169230,ENSG00000124299,ENSG00000153094,ENSG00000123416,ENSG00000150636,ENSG00000152229,ENSG00000065135,ENSG00000213445,ENSG00000213281,ENSG00000163520,ENSG00000123131,ENSG00000159200,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000041353,ENSG00000089127,ENSG00000167723,ENSG00000075420,ENSG00000152256,ENSG00000204472,ENSG00000089685,ENSG00000121297,ENSG00000163041,ENSG00000044574,ENSG00000133315,ENSG00000124587,ENSG00000188612,ENSG00000181938,ENSG00000130741,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000064666,ENSG00000072958,ENSG00000132274,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000073803,ENSG00000104805,ENSG00000179632,ENSG00000159873,ENSG00000163545,ENSG00000152778,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000166974,ENSG00000142556,ENSG00000166454,ENSG00000204899,ENSG00000180667,ENSG00000129422,ENSG00000166197,ENSG00000204822,ENSG00000154001,ENSG00000126016,ENSG00000241258,ENSG00000206127,ENSG00000131931,ENSG00000138071,ENSG00000100897,ENSG00000166598,ENSG00000131236,ENSG00000157985,ENSG00000110448,ENSG00000107317,ENSG00000111348,ENSG00000132661,ENSG00000148730,ENSG00000100342,ENSG00000156234,ENSG00000108798,ENSG00000129675,ENSG00000118971,ENSG00000129534,ENSG00000084090,ENSG00000021355,ENSG00000196954,ENSG00000183475,ENSG00000177613,ENSG00000093009,ENSG00000101444,ENSG00000185650,ENSG00000111331,ENSG00000074800,ENSG00000143476,ENSG00000084623,ENSG00000172803,ENSG00000122952,ENSG00000105220,ENSG00000143228,ENSG00000181467,ENSG00000158869,ENSG00000171222,ENSG00000172164,ENSG00000053254,ENSG00000145649,ENSG00000136717,ENSG00000116983,ENSG00000071994,ENSG00000168421,ENSG00000181191,ENSG00000155368,ENSG00000100299,ENSG00000013725,ENSG00000134909,ENSG00000163131,ENSG00000172731,ENSG00000170881,ENSG00000100385,ENSG00000179715,ENSG00000125148,ENSG00000131504,ENSG00000184916,ENSG00000075151,ENSG00000198821,ENSG00000011485,ENSG00000067560,ENSG00000213928,ENSG00000125944,ENSG00000127952,ENSG00000116667,ENSG00000183172,ENSG00000114166,ENSG00000049449,ENSG00000189283,ENSG00000213719,ENSG00000165304,ENSG00000186648,ENSG00000134202,ENSG00000172794,ENSG00000075340,ENSG00000133026,ENSG00000174684,ENSG00000113810,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000144597,ENSG00000204642,ENSG00000115267,ENSG00000204256,ENSG00000143727,ENSG00000185262,ENSG00000087302,ENSG00000006625,ENSG00000151743,ENSG00000151466,ENSG00000168961,ENSG00000158113,ENSG00000122122,ENSG00000158882,ENSG00000180938,ENSG00000172270,ENSG00000122877,ENSG00000165283,ENSG00000173517,ENSG00000172795,ENSG00000148175,ENSG00000131747,ENSG00000184887,ENSG00000171617,ENSG00000141736,ENSG00000132963,ENSG00000162702,ENSG00000204592,ENSG00000132792,ENSG00000083444,ENSG00000103994,ENSG00000158321,ENSG00000237190,ENSG00000174371,ENSG00000118564,ENSG00000160877,ENSG00000129625,ENSG00000213626,ENSG00000167286,ENSG00000187608,ENSG00000157873,ENSG00000189369,ENSG00000082153,ENSG00000139579,ENSG00000103495,ENSG00000162676,ENSG00000106462,ENSG00000042753,ENSG00000153310,ENSG00000178996,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000152253,ENSG00000079691,ENSG00000172936,ENSG00000170860,ENSG00000171169,ENSG00000151239,ENSG00000118705,ENSG00000128294,ENSG00000179583,ENSG00000171302,ENSG00000153790,ENSG00000178719,ENSG00000166035,ENSG00000141030,ENSG00000147234,ENSG00000197043,ENSG00000054965,ENSG00000189266,ENSG00000132670,ENSG00000066279,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000176542,ENSG00000128394,ENSG00000075239,ENSG00000176641,ENSG00000130348,ENSG00000136824,ENSG00000079999,ENSG00000113068,ENSG00000165527,ENSG00000117155,ENSG00000162385,ENSG00000168329,ENSG00000127666,ENSG00000159111,ENSG00000139370,ENSG00000109084,ENSG00000105697,ENSG00000127022,ENSG00000197956,ENSG00000109805,ENSG00000026751,ENSG00000121579,ENSG00000148908,ENSG00000196072,ENSG00000138617,ENSG00000184897,ENSG00000102931,ENSG00000125648,ENSG00000189376,ENSG00000116670,ENSG00000184154,ENSG00000072571,ENSG00000055163,ENSG00000185880,ENSG00000184640,ENSG00000090520,ENSG00000132386,ENSG00000127774,ENSG00000123338,ENSG00000010270,ENSG00000109536,ENSG00000140450,ENSG00000171943,ENSG00000128272,ENSG00000148337,ENSG00000124688,ENSG00000120709,ENSG00000142867,ENSG00000110852,ENSG00000111335,ENSG00000114126,ENSG00000160051,ENSG00000250486,ENSG00000143740,ENSG00000126432,ENSG00000124155,ENSG00000146112,ENSG00000198736,ENSG00000145337,ENSG00000138646,ENSG00000049541,ENSG00000196834,ENSG00000175283,ENSG00000104738,ENSG00000119318,ENSG00000172531,ENSG00000168765,ENSG00000178691,ENSG00000129968,ENSG00000257390,ENSG00000153044,ENSG00000140284,ENSG00000137309,ENSG00000132321,ENSG00000041357,ENSG00000125354,ENSG00000125870,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000152601,ENSG00000189306,ENSG00000104472,ENSG00000067840,ENSG00000066583,ENSG00000092841,ENSG00000091127,ENSG00000213366,ENSG00000140319,ENSG00000182628,ENSG00000111796,ENSG00000137310,ENSG00000155660,ENSG00000101082,ENSG00000164576,ENSG00000131019,ENSG00000197409,ENSG00000172667,ENSG00000173660,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000132388,ENSG00000143321,ENSG00000089693,ENSG00000155090,ENSG00000148218,ENSG00000242574,ENSG00000147168,ENSG00000203950,ENSG00000134690,ENSG00000184575,ENSG00000177674,ENSG00000135960,ENSG00000011007,ENSG00000028137,ENSG00000160753,ENSG00000178685,ENSG00000169223,ENSG00000132256,ENSG00000147889,ENSG00000139926,ENSG00000140575,ENSG00000137193,ENSG00000146859,ENSG00000160404,ENSG00000111450,ENSG00000155096,ENSG00000175104,ENSG00000196642,ENSG00000110218,ENSG00000169554,ENSG00000127084,ENSG00000113387,ENSG00000166794,ENSG00000114631,ENSG00000111859,ENSG00000147180,ENSG00000170485,ENSG00000130818,ENSG00000081985 |
| GO:0044877 | protein-containing complex binding | 0.0000005 | 1241 | 718 | 94 | 0.1309192 | 0.0757454 | GO:MF | ENSG00000117281,ENSG00000196126,ENSG00000072110,ENSG00000117724,ENSG00000179218,ENSG00000002834,ENSG00000184357,ENSG00000100427,ENSG00000080573,ENSG00000155657,ENSG00000231925,ENSG00000019582,ENSG00000203747,ENSG00000130164,ENSG00000069702,ENSG00000205336,ENSG00000125868,ENSG00000169252,ENSG00000160654,ENSG00000196924,ENSG00000112029,ENSG00000150093,ENSG00000136167,ENSG00000077312,ENSG00000172757,ENSG00000134539,ENSG00000117228,ENSG00000100749,ENSG00000139626,ENSG00000132646,ENSG00000153563,ENSG00000100380,ENSG00000128335,ENSG00000005844,ENSG00000137474,ENSG00000116288,ENSG00000196230,ENSG00000124575,ENSG00000143742,ENSG00000131018,ENSG00000130402,ENSG00000092853,ENSG00000215305,ENSG00000242372,ENSG00000065135,ENSG00000213281,ENSG00000204472,ENSG00000163041,ENSG00000044574,ENSG00000124587,ENSG00000111229,ENSG00000073803,ENSG00000166454,ENSG00000166197,ENSG00000253626,ENSG00000138071,ENSG00000112031,ENSG00000115155,ENSG00000143228,ENSG00000158869,ENSG00000136717,ENSG00000163131,ENSG00000011485,ENSG00000075340,ENSG00000133026,ENSG00000115267,ENSG00000204592,ENSG00000187608,ENSG00000106462,ENSG00000153310,ENSG00000079691,ENSG00000151239,ENSG00000118705,ENSG00000179583,ENSG00000166035,ENSG00000197043,ENSG00000075624,ENSG00000184897,ENSG00000123338,ENSG00000109536,ENSG00000142867,ENSG00000119318,ENSG00000172531,ENSG00000125870,ENSG00000254087,ENSG00000160255,ENSG00000164576,ENSG00000198851,ENSG00000148218,ENSG00000242574,ENSG00000140575,ENSG00000137193,ENSG00000110218,ENSG00000166794 |
| GO:0042287 | MHC protein binding | 0.0000010 | 40 | 718 | 13 | 0.0181058 | 0.3250000 | GO:MF | ENSG00000204267,ENSG00000089692,ENSG00000181036,ENSG00000231925,ENSG00000019582,ENSG00000134539,ENSG00000153563,ENSG00000196230,ENSG00000122223,ENSG00000172116,ENSG00000211810,ENSG00000204592,ENSG00000153310 |
| GO:0042605 | peptide antigen binding | 0.0000297 | 29 | 718 | 10 | 0.0139276 | 0.3448276 | GO:MF | ENSG00000179344,ENSG00000196126,ENSG00000092068,ENSG00000196735,ENSG00000231925,ENSG00000223865,ENSG00000231389,ENSG00000211810,ENSG00000204642,ENSG00000204592 |
| GO:0019899 | enzyme binding | 0.0000511 | 2246 | 718 | 136 | 0.1894150 | 0.0605521 | GO:MF | ENSG00000179344,ENSG00000156587,ENSG00000138496,ENSG00000113721,ENSG00000117281,ENSG00000179218,ENSG00000184357,ENSG00000147459,ENSG00000134184,ENSG00000155657,ENSG00000163840,ENSG00000181036,ENSG00000019582,ENSG00000160014,ENSG00000130164,ENSG00000115415,ENSG00000164111,ENSG00000113368,ENSG00000163029,ENSG00000170315,ENSG00000105639,ENSG00000169252,ENSG00000196924,ENSG00000118193,ENSG00000112029,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000173848,ENSG00000138160,ENSG00000165617,ENSG00000111206,ENSG00000138795,ENSG00000179051,ENSG00000232810,ENSG00000117228,ENSG00000204397,ENSG00000100749,ENSG00000132646,ENSG00000108518,ENSG00000116288,ENSG00000196230,ENSG00000175793,ENSG00000156463,ENSG00000143543,ENSG00000131018,ENSG00000188191,ENSG00000187446,ENSG00000011426,ENSG00000185651,ENSG00000117394,ENSG00000185304,ENSG00000152969,ENSG00000153094,ENSG00000123416,ENSG00000148400,ENSG00000089685,ENSG00000044574,ENSG00000188612,ENSG00000116030,ENSG00000132274,ENSG00000073803,ENSG00000104805,ENSG00000179632,ENSG00000147065,ENSG00000166974,ENSG00000180667,ENSG00000166197,ENSG00000166598,ENSG00000131236,ENSG00000111348,ENSG00000132661,ENSG00000129675,ENSG00000118971,ENSG00000074800,ENSG00000105220,ENSG00000136717,ENSG00000071994,ENSG00000168421,ENSG00000170881,ENSG00000131504,ENSG00000198821,ENSG00000067560,ENSG00000127952,ENSG00000114166,ENSG00000189283,ENSG00000134202,ENSG00000075340,ENSG00000087302,ENSG00000168961,ENSG00000122877,ENSG00000165283,ENSG00000148175,ENSG00000131747,ENSG00000141736,ENSG00000132792,ENSG00000187608,ENSG00000157873,ENSG00000139579,ENSG00000070831,ENSG00000075624,ENSG00000096968,ENSG00000075239,ENSG00000176641,ENSG00000165527,ENSG00000127666,ENSG00000138617,ENSG00000116670,ENSG00000123338,ENSG00000171943,ENSG00000128272,ENSG00000142867,ENSG00000146112,ENSG00000049541,ENSG00000172531,ENSG00000168765,ENSG00000140284,ENSG00000137309,ENSG00000254087,ENSG00000160255,ENSG00000091127,ENSG00000213366,ENSG00000137312,ENSG00000198851,ENSG00000132388,ENSG00000184575,ENSG00000028137,ENSG00000132256,ENSG00000147889,ENSG00000140575,ENSG00000175104,ENSG00000110218,ENSG00000127084,ENSG00000166794,ENSG00000111859,ENSG00000081985 |
| GO:0001882 | nucleoside binding | 0.0002409 | 394 | 718 | 37 | 0.0515320 | 0.0939086 | GO:MF | ENSG00000154451,ENSG00000162654,ENSG00000198513,ENSG00000213512,ENSG00000167461,ENSG00000125249,ENSG00000117228,ENSG00000103769,ENSG00000117226,ENSG00000084092,ENSG00000196230,ENSG00000103966,ENSG00000130402,ENSG00000123416,ENSG00000065135,ENSG00000213281,ENSG00000157601,ENSG00000041353,ENSG00000130741,ENSG00000166197,ENSG00000157985,ENSG00000137959,ENSG00000181467,ENSG00000168421,ENSG00000180574,ENSG00000067560,ENSG00000172794,ENSG00000189369,ENSG00000070831,ENSG00000179583,ENSG00000197043,ENSG00000165527,ENSG00000184640,ENSG00000125354,ENSG00000139998,ENSG00000196839,ENSG00000196642 |
| GO:0042802 | identical protein binding | 0.0002409 | 1756 | 718 | 109 | 0.1518106 | 0.0620729 | GO:MF | ENSG00000004468,ENSG00000072110,ENSG00000117724,ENSG00000165891,ENSG00000154451,ENSG00000162654,ENSG00000134184,ENSG00000155657,ENSG00000057704,ENSG00000097021,ENSG00000123485,ENSG00000019582,ENSG00000198513,ENSG00000173482,ENSG00000130164,ENSG00000115415,ENSG00000119917,ENSG00000155629,ENSG00000100911,ENSG00000171848,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000175550,ENSG00000136167,ENSG00000123609,ENSG00000077312,ENSG00000110090,ENSG00000232810,ENSG00000183691,ENSG00000117228,ENSG00000134308,ENSG00000176890,ENSG00000204397,ENSG00000111640,ENSG00000118777,ENSG00000134352,ENSG00000132646,ENSG00000100380,ENSG00000117226,ENSG00000137474,ENSG00000116288,ENSG00000180644,ENSG00000073008,ENSG00000175793,ENSG00000169855,ENSG00000131018,ENSG00000077984,ENSG00000130402,ENSG00000136436,ENSG00000117394,ENSG00000070018,ENSG00000165949,ENSG00000055332,ENSG00000239713,ENSG00000157601,ENSG00000089685,ENSG00000166710,ENSG00000073803,ENSG00000166974,ENSG00000131931,ENSG00000108798,ENSG00000101444,ENSG00000074800,ENSG00000158869,ENSG00000171222,ENSG00000145649,ENSG00000136717,ENSG00000013725,ENSG00000198821,ENSG00000011485,ENSG00000189283,ENSG00000134202,ENSG00000075340,ENSG00000115267,ENSG00000087302,ENSG00000006625,ENSG00000173517,ENSG00000148175,ENSG00000131747,ENSG00000141736,ENSG00000167286,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000172936,ENSG00000128294,ENSG00000171302,ENSG00000197043,ENSG00000075624,ENSG00000096968,ENSG00000128394,ENSG00000075239,ENSG00000079999,ENSG00000197956,ENSG00000026751,ENSG00000010270,ENSG00000171943,ENSG00000142867,ENSG00000110852,ENSG00000168765,ENSG00000213366,ENSG00000198851,ENSG00000148218,ENSG00000132256,ENSG00000160404,ENSG00000175104,ENSG00000113387 |
| GO:0001883 | purine nucleoside binding | 0.0003221 | 387 | 718 | 36 | 0.0501393 | 0.0930233 | GO:MF | ENSG00000154451,ENSG00000162654,ENSG00000198513,ENSG00000213512,ENSG00000167461,ENSG00000125249,ENSG00000117228,ENSG00000103769,ENSG00000117226,ENSG00000084092,ENSG00000196230,ENSG00000103966,ENSG00000123416,ENSG00000065135,ENSG00000213281,ENSG00000157601,ENSG00000041353,ENSG00000130741,ENSG00000166197,ENSG00000157985,ENSG00000137959,ENSG00000181467,ENSG00000168421,ENSG00000180574,ENSG00000067560,ENSG00000172794,ENSG00000189369,ENSG00000070831,ENSG00000179583,ENSG00000197043,ENSG00000165527,ENSG00000184640,ENSG00000125354,ENSG00000139998,ENSG00000196839,ENSG00000196642 |
| GO:0003924 | GTPase activity | 0.0003890 | 328 | 718 | 32 | 0.0445682 | 0.0975610 | GO:MF | ENSG00000154451,ENSG00000162654,ENSG00000198513,ENSG00000186469,ENSG00000213512,ENSG00000167461,ENSG00000125249,ENSG00000117228,ENSG00000103769,ENSG00000117226,ENSG00000196230,ENSG00000123416,ENSG00000065135,ENSG00000213281,ENSG00000157601,ENSG00000041353,ENSG00000130741,ENSG00000157985,ENSG00000111348,ENSG00000181467,ENSG00000168421,ENSG00000180574,ENSG00000067560,ENSG00000172794,ENSG00000189369,ENSG00000070831,ENSG00000165527,ENSG00000148908,ENSG00000184640,ENSG00000125354,ENSG00000139998,ENSG00000143248 |
| GO:0005525 | GTP binding | 0.0004466 | 380 | 718 | 35 | 0.0487465 | 0.0921053 | GO:MF | ENSG00000154451,ENSG00000162654,ENSG00000198513,ENSG00000213512,ENSG00000167461,ENSG00000125249,ENSG00000117228,ENSG00000103769,ENSG00000117226,ENSG00000084092,ENSG00000196230,ENSG00000103966,ENSG00000123416,ENSG00000065135,ENSG00000213281,ENSG00000157601,ENSG00000041353,ENSG00000130741,ENSG00000166197,ENSG00000157985,ENSG00000137959,ENSG00000181467,ENSG00000168421,ENSG00000180574,ENSG00000067560,ENSG00000172794,ENSG00000189369,ENSG00000070831,ENSG00000179583,ENSG00000197043,ENSG00000165527,ENSG00000184640,ENSG00000125354,ENSG00000139998,ENSG00000196642 |
| GO:0032550 | purine ribonucleoside binding | 0.0004702 | 384 | 718 | 35 | 0.0487465 | 0.0911458 | GO:MF | ENSG00000154451,ENSG00000162654,ENSG00000198513,ENSG00000213512,ENSG00000167461,ENSG00000125249,ENSG00000117228,ENSG00000103769,ENSG00000117226,ENSG00000084092,ENSG00000196230,ENSG00000103966,ENSG00000123416,ENSG00000065135,ENSG00000213281,ENSG00000157601,ENSG00000041353,ENSG00000130741,ENSG00000166197,ENSG00000157985,ENSG00000137959,ENSG00000181467,ENSG00000168421,ENSG00000180574,ENSG00000067560,ENSG00000172794,ENSG00000189369,ENSG00000070831,ENSG00000179583,ENSG00000197043,ENSG00000165527,ENSG00000184640,ENSG00000125354,ENSG00000139998,ENSG00000196642 |
| GO:0003779 | actin binding | 0.0004702 | 433 | 718 | 38 | 0.0529248 | 0.0877598 | GO:MF | ENSG00000248905,ENSG00000072110,ENSG00000002834,ENSG00000155657,ENSG00000034510,ENSG00000125868,ENSG00000196924,ENSG00000150093,ENSG00000136167,ENSG00000172757,ENSG00000117228,ENSG00000108518,ENSG00000130592,ENSG00000137474,ENSG00000131018,ENSG00000130402,ENSG00000011426,ENSG00000215305,ENSG00000152229,ENSG00000204472,ENSG00000064666,ENSG00000111229,ENSG00000147065,ENSG00000138071,ENSG00000131236,ENSG00000172164,ENSG00000136717,ENSG00000131504,ENSG00000075340,ENSG00000133026,ENSG00000171617,ENSG00000151239,ENSG00000197043,ENSG00000109536,ENSG00000146112,ENSG00000198736,ENSG00000160753,ENSG00000110218 |
| GO:0032549 | ribonucleoside binding | 0.0005158 | 387 | 718 | 35 | 0.0487465 | 0.0904393 | GO:MF | ENSG00000154451,ENSG00000162654,ENSG00000198513,ENSG00000213512,ENSG00000167461,ENSG00000125249,ENSG00000117228,ENSG00000103769,ENSG00000117226,ENSG00000084092,ENSG00000196230,ENSG00000103966,ENSG00000123416,ENSG00000065135,ENSG00000213281,ENSG00000157601,ENSG00000041353,ENSG00000130741,ENSG00000166197,ENSG00000157985,ENSG00000137959,ENSG00000181467,ENSG00000168421,ENSG00000180574,ENSG00000067560,ENSG00000172794,ENSG00000189369,ENSG00000070831,ENSG00000179583,ENSG00000197043,ENSG00000165527,ENSG00000184640,ENSG00000125354,ENSG00000139998,ENSG00000196642 |
| GO:0008092 | cytoskeletal protein binding | 0.0006297 | 991 | 718 | 68 | 0.0947075 | 0.0686176 | GO:MF | ENSG00000196169,ENSG00000183688,ENSG00000248905,ENSG00000072110,ENSG00000129595,ENSG00000002834,ENSG00000155657,ENSG00000160014,ENSG00000034510,ENSG00000091129,ENSG00000166503,ENSG00000125868,ENSG00000117632,ENSG00000196924,ENSG00000118193,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000138160,ENSG00000172757,ENSG00000179051,ENSG00000117228,ENSG00000111640,ENSG00000103769,ENSG00000108518,ENSG00000130592,ENSG00000137474,ENSG00000131018,ENSG00000187446,ENSG00000130402,ENSG00000011426,ENSG00000171603,ENSG00000152969,ENSG00000061337,ENSG00000215305,ENSG00000153094,ENSG00000152229,ENSG00000157601,ENSG00000041353,ENSG00000204472,ENSG00000089685,ENSG00000064666,ENSG00000111229,ENSG00000147065,ENSG00000166974,ENSG00000129422,ENSG00000138071,ENSG00000131236,ENSG00000172164,ENSG00000136717,ENSG00000131504,ENSG00000011485,ENSG00000067560,ENSG00000075340,ENSG00000133026,ENSG00000171617,ENSG00000151239,ENSG00000197043,ENSG00000075624,ENSG00000197956,ENSG00000196072,ENSG00000109536,ENSG00000146112,ENSG00000198736,ENSG00000254087,ENSG00000182628,ENSG00000160753,ENSG00000110218 |
| GO:0042288 | MHC class I protein binding | 0.0006424 | 20 | 718 | 7 | 0.0097493 | 0.3500000 | GO:MF | ENSG00000204267,ENSG00000231925,ENSG00000153563,ENSG00000196230,ENSG00000122223,ENSG00000172116,ENSG00000204592 |
| GO:0032561 | guanyl ribonucleotide binding | 0.0008570 | 401 | 718 | 35 | 0.0487465 | 0.0872818 | GO:MF | ENSG00000154451,ENSG00000162654,ENSG00000198513,ENSG00000213512,ENSG00000167461,ENSG00000125249,ENSG00000117228,ENSG00000103769,ENSG00000117226,ENSG00000084092,ENSG00000196230,ENSG00000103966,ENSG00000123416,ENSG00000065135,ENSG00000213281,ENSG00000157601,ENSG00000041353,ENSG00000130741,ENSG00000166197,ENSG00000157985,ENSG00000137959,ENSG00000181467,ENSG00000168421,ENSG00000180574,ENSG00000067560,ENSG00000172794,ENSG00000189369,ENSG00000070831,ENSG00000179583,ENSG00000197043,ENSG00000165527,ENSG00000184640,ENSG00000125354,ENSG00000139998,ENSG00000196642 |
| GO:0019001 | guanyl nucleotide binding | 0.0008570 | 401 | 718 | 35 | 0.0487465 | 0.0872818 | GO:MF | ENSG00000154451,ENSG00000162654,ENSG00000198513,ENSG00000213512,ENSG00000167461,ENSG00000125249,ENSG00000117228,ENSG00000103769,ENSG00000117226,ENSG00000084092,ENSG00000196230,ENSG00000103966,ENSG00000123416,ENSG00000065135,ENSG00000213281,ENSG00000157601,ENSG00000041353,ENSG00000130741,ENSG00000166197,ENSG00000157985,ENSG00000137959,ENSG00000181467,ENSG00000168421,ENSG00000180574,ENSG00000067560,ENSG00000172794,ENSG00000189369,ENSG00000070831,ENSG00000179583,ENSG00000197043,ENSG00000165527,ENSG00000184640,ENSG00000125354,ENSG00000139998,ENSG00000196642 |
| GO:0042277 | peptide binding | 0.0011199 | 308 | 718 | 29 | 0.0403900 | 0.0941558 | GO:MF | ENSG00000164308,ENSG00000179344,ENSG00000196126,ENSG00000179218,ENSG00000092068,ENSG00000134184,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000130164,ENSG00000164111,ENSG00000223865,ENSG00000231389,ENSG00000169252,ENSG00000105409,ENSG00000108179,ENSG00000171596,ENSG00000171603,ENSG00000211810,ENSG00000166197,ENSG00000134202,ENSG00000204642,ENSG00000158882,ENSG00000204592,ENSG00000168765,ENSG00000160255,ENSG00000213366,ENSG00000140319,ENSG00000166794 |
| GO:0033218 | amide binding | 0.0017513 | 366 | 718 | 32 | 0.0445682 | 0.0874317 | GO:MF | ENSG00000164308,ENSG00000179344,ENSG00000196126,ENSG00000179218,ENSG00000092068,ENSG00000134184,ENSG00000097021,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000130164,ENSG00000164111,ENSG00000223865,ENSG00000231389,ENSG00000169252,ENSG00000105409,ENSG00000176890,ENSG00000108179,ENSG00000171596,ENSG00000171603,ENSG00000211810,ENSG00000166197,ENSG00000155368,ENSG00000134202,ENSG00000204642,ENSG00000158882,ENSG00000204592,ENSG00000168765,ENSG00000160255,ENSG00000213366,ENSG00000140319,ENSG00000166794 |
| GO:0023023 | MHC protein complex binding | 0.0018727 | 24 | 718 | 7 | 0.0097493 | 0.2916667 | GO:MF | ENSG00000117281,ENSG00000196126,ENSG00000019582,ENSG00000134539,ENSG00000153563,ENSG00000153310,ENSG00000242574 |
| GO:0051015 | actin filament binding | 0.0021865 | 196 | 718 | 21 | 0.0292479 | 0.1071429 | GO:MF | ENSG00000072110,ENSG00000002834,ENSG00000155657,ENSG00000125868,ENSG00000196924,ENSG00000136167,ENSG00000172757,ENSG00000137474,ENSG00000131018,ENSG00000130402,ENSG00000215305,ENSG00000204472,ENSG00000111229,ENSG00000138071,ENSG00000136717,ENSG00000075340,ENSG00000133026,ENSG00000151239,ENSG00000197043,ENSG00000109536,ENSG00000110218 |
| GO:0005488 | binding | 0.0023155 | 15944 | 718 | 664 | 0.9247911 | 0.0416458 | GO:MF | ENSG00000172057,ENSG00000137441,ENSG00000100453,ENSG00000004468,ENSG00000196169,ENSG00000148773,ENSG00000164308,ENSG00000179344,ENSG00000152217,ENSG00000156587,ENSG00000119922,ENSG00000138496,ENSG00000204267,ENSG00000113721,ENSG00000176083,ENSG00000142634,ENSG00000117281,ENSG00000196126,ENSG00000183688,ENSG00000007402,ENSG00000229474,ENSG00000092010,ENSG00000248905,ENSG00000072110,ENSG00000129595,ENSG00000073605,ENSG00000073861,ENSG00000156886,ENSG00000163599,ENSG00000132530,ENSG00000117724,ENSG00000125347,ENSG00000105374,ENSG00000221963,ENSG00000108679,ENSG00000100321,ENSG00000109956,ENSG00000179218,ENSG00000163492,ENSG00000002834,ENSG00000126709,ENSG00000159674,ENSG00000184357,ENSG00000135077,ENSG00000090857,ENSG00000092068,ENSG00000165891,ENSG00000147459,ENSG00000154451,ENSG00000162654,ENSG00000100427,ENSG00000080573,ENSG00000134184,ENSG00000155657,ENSG00000163840,ENSG00000057704,ENSG00000089692,ENSG00000181036,ENSG00000097021,ENSG00000196735,ENSG00000182054,ENSG00000163421,ENSG00000123485,ENSG00000231925,ENSG00000019582,ENSG00000117560,ENSG00000198513,ENSG00000072135,ENSG00000164649,ENSG00000203747,ENSG00000159216,ENSG00000151502,ENSG00000160014,ENSG00000034510,ENSG00000173482,ENSG00000130164,ENSG00000127124,ENSG00000115415,ENSG00000143870,ENSG00000119917,ENSG00000155629,ENSG00000186469,ENSG00000069702,ENSG00000091129,ENSG00000100911,ENSG00000197928,ENSG00000130511,ENSG00000221866,ENSG00000205336,ENSG00000164111,ENSG00000124191,ENSG00000198046,ENSG00000113368,ENSG00000101057,ENSG00000177156,ENSG00000163029,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000166503,ENSG00000156970,ENSG00000171848,ENSG00000213512,ENSG00000125868,ENSG00000105639,ENSG00000125864,ENSG00000117632,ENSG00000142089,ENSG00000169252,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000146674,ENSG00000175550,ENSG00000118193,ENSG00000112029,ENSG00000065911,ENSG00000120057,ENSG00000117984,ENSG00000127947,ENSG00000186470,ENSG00000157216,ENSG00000150093,ENSG00000136167,ENSG00000167461,ENSG00000105409,ENSG00000123609,ENSG00000165512,ENSG00000173848,ENSG00000138160,ENSG00000096996,ENSG00000077312,ENSG00000165617,ENSG00000172331,ENSG00000125249,ENSG00000173114,ENSG00000111206,ENSG00000133321,ENSG00000172757,ENSG00000138795,ENSG00000110090,ENSG00000111537,ENSG00000102554,ENSG00000111885,ENSG00000179051,ENSG00000112139,ENSG00000189430,ENSG00000099194,ENSG00000232810,ENSG00000183691,ENSG00000134539,ENSG00000117228,ENSG00000138180,ENSG00000134308,ENSG00000126787,ENSG00000176890,ENSG00000204397,ENSG00000176293,ENSG00000133739,ENSG00000100749,ENSG00000108179,ENSG00000111640,ENSG00000118777,ENSG00000183734,ENSG00000172292,ENSG00000134352,ENSG00000139626,ENSG00000167914,ENSG00000132646,ENSG00000153563,ENSG00000103769,ENSG00000100380,ENSG00000108518,ENSG00000128335,ENSG00000117226,ENSG00000183741,ENSG00000128284,ENSG00000131171,ENSG00000005844,ENSG00000130592,ENSG00000103148,ENSG00000084092,ENSG00000137474,ENSG00000116288,ENSG00000196230,ENSG00000134765,ENSG00000103512,ENSG00000171596,ENSG00000180644,ENSG00000111602,ENSG00000103202,ENSG00000106868,ENSG00000122121,ENSG00000073008,ENSG00000075234,ENSG00000135114,ENSG00000134321,ENSG00000249437,ENSG00000175793,ENSG00000169855,ENSG00000103966,ENSG00000124575,ENSG00000189420,ENSG00000023572,ENSG00000100918,ENSG00000152465,ENSG00000172508,ENSG00000156463,ENSG00000143543,ENSG00000106392,ENSG00000204264,ENSG00000173821,ENSG00000143742,ENSG00000105011,ENSG00000051341,ENSG00000131018,ENSG00000205413,ENSG00000196976,ENSG00000188191,ENSG00000077984,ENSG00000114978,ENSG00000187446,ENSG00000130402,ENSG00000188312,ENSG00000011426,ENSG00000071205,ENSG00000170312,ENSG00000170222,ENSG00000105887,ENSG00000110060,ENSG00000167618,ENSG00000155846,ENSG00000122223,ENSG00000136436,ENSG00000197568,ENSG00000185885,ENSG00000163359,ENSG00000185651,ENSG00000141576,ENSG00000117394,ENSG00000172116,ENSG00000131944,ENSG00000070018,ENSG00000139182,ENSG00000171603,ENSG00000165949,ENSG00000185304,ENSG00000152969,ENSG00000092853,ENSG00000061337,ENSG00000215305,ENSG00000055332,ENSG00000239713,ENSG00000242372,ENSG00000169230,ENSG00000124299,ENSG00000153094,ENSG00000123416,ENSG00000150636,ENSG00000152229,ENSG00000065135,ENSG00000213445,ENSG00000104687,ENSG00000213281,ENSG00000163520,ENSG00000123131,ENSG00000159200,ENSG00000122971,ENSG00000119335,ENSG00000148400,ENSG00000157601,ENSG00000164211,ENSG00000041353,ENSG00000089127,ENSG00000167723,ENSG00000075420,ENSG00000152256,ENSG00000204472,ENSG00000089685,ENSG00000121297,ENSG00000163041,ENSG00000044574,ENSG00000133315,ENSG00000124587,ENSG00000188612,ENSG00000171246,ENSG00000181938,ENSG00000130741,ENSG00000116030,ENSG00000007968,ENSG00000165030,ENSG00000118263,ENSG00000064666,ENSG00000072958,ENSG00000132274,ENSG00000173786,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000073803,ENSG00000104805,ENSG00000179632,ENSG00000159873,ENSG00000163545,ENSG00000152778,ENSG00000185745,ENSG00000163823,ENSG00000233757,ENSG00000147065,ENSG00000166974,ENSG00000142556,ENSG00000166454,ENSG00000204899,ENSG00000180667,ENSG00000129422,ENSG00000166197,ENSG00000204822,ENSG00000154001,ENSG00000126016,ENSG00000241258,ENSG00000206127,ENSG00000253626,ENSG00000131931,ENSG00000171970,ENSG00000138071,ENSG00000100897,ENSG00000166598,ENSG00000129007,ENSG00000131236,ENSG00000157985,ENSG00000110448,ENSG00000107317,ENSG00000111348,ENSG00000137959,ENSG00000132661,ENSG00000148730,ENSG00000100342,ENSG00000156234,ENSG00000108798,ENSG00000129675,ENSG00000225921,ENSG00000112031,ENSG00000118971,ENSG00000129534,ENSG00000084090,ENSG00000021355,ENSG00000196954,ENSG00000183475,ENSG00000177613,ENSG00000115155,ENSG00000093009,ENSG00000101444,ENSG00000185650,ENSG00000100605,ENSG00000111331,ENSG00000074800,ENSG00000143476,ENSG00000084623,ENSG00000172803,ENSG00000122952,ENSG00000105220,ENSG00000143228,ENSG00000181467,ENSG00000158869,ENSG00000171222,ENSG00000196449,ENSG00000172164,ENSG00000053254,ENSG00000145649,ENSG00000136717,ENSG00000116983,ENSG00000071994,ENSG00000168421,ENSG00000181191,ENSG00000155368,ENSG00000100299,ENSG00000013725,ENSG00000134909,ENSG00000158006,ENSG00000163131,ENSG00000172731,ENSG00000170881,ENSG00000100385,ENSG00000179715,ENSG00000125148,ENSG00000131504,ENSG00000184916,ENSG00000180574,ENSG00000075151,ENSG00000198821,ENSG00000011485,ENSG00000067560,ENSG00000132932,ENSG00000197417,ENSG00000154027,ENSG00000213928,ENSG00000125944,ENSG00000127952,ENSG00000064886,ENSG00000116667,ENSG00000183172,ENSG00000114166,ENSG00000049449,ENSG00000189283,ENSG00000213719,ENSG00000165304,ENSG00000186648,ENSG00000134202,ENSG00000172794,ENSG00000075340,ENSG00000133026,ENSG00000174684,ENSG00000113810,ENSG00000115520,ENSG00000149294,ENSG00000185507,ENSG00000100298,ENSG00000144597,ENSG00000204642,ENSG00000115267,ENSG00000204256,ENSG00000143727,ENSG00000185262,ENSG00000087302,ENSG00000006625,ENSG00000151743,ENSG00000151466,ENSG00000168961,ENSG00000172081,ENSG00000158113,ENSG00000115339,ENSG00000122122,ENSG00000158882,ENSG00000180938,ENSG00000172270,ENSG00000122877,ENSG00000165283,ENSG00000173517,ENSG00000172795,ENSG00000148175,ENSG00000131747,ENSG00000184887,ENSG00000171617,ENSG00000141736,ENSG00000132963,ENSG00000162702,ENSG00000204592,ENSG00000132792,ENSG00000083444,ENSG00000103994,ENSG00000158321,ENSG00000237190,ENSG00000174371,ENSG00000116771,ENSG00000118564,ENSG00000160877,ENSG00000002549,ENSG00000129625,ENSG00000213626,ENSG00000167286,ENSG00000187608,ENSG00000157873,ENSG00000189369,ENSG00000021762,ENSG00000082153,ENSG00000198843,ENSG00000139579,ENSG00000103495,ENSG00000162676,ENSG00000106462,ENSG00000042753,ENSG00000153310,ENSG00000178996,ENSG00000176101,ENSG00000104765,ENSG00000070831,ENSG00000152253,ENSG00000079691,ENSG00000172936,ENSG00000112996,ENSG00000124920,ENSG00000170860,ENSG00000171169,ENSG00000151239,ENSG00000118705,ENSG00000164088,ENSG00000243660,ENSG00000128294,ENSG00000179583,ENSG00000171302,ENSG00000153790,ENSG00000178719,ENSG00000166035,ENSG00000141030,ENSG00000147234,ENSG00000197142,ENSG00000197043,ENSG00000054965,ENSG00000189266,ENSG00000132670,ENSG00000066279,ENSG00000075624,ENSG00000113369,ENSG00000096968,ENSG00000164164,ENSG00000176542,ENSG00000128394,ENSG00000258289,ENSG00000075239,ENSG00000176641,ENSG00000130348,ENSG00000109674,ENSG00000136824,ENSG00000079999,ENSG00000113068,ENSG00000165527,ENSG00000117155,ENSG00000105612,ENSG00000162385,ENSG00000171954,ENSG00000168329,ENSG00000162104,ENSG00000127666,ENSG00000159111,ENSG00000139370,ENSG00000109084,ENSG00000105697,ENSG00000223496,ENSG00000127022,ENSG00000197956,ENSG00000109805,ENSG00000026751,ENSG00000121579,ENSG00000138018,ENSG00000148908,ENSG00000196072,ENSG00000138617,ENSG00000184897,ENSG00000102931,ENSG00000125648,ENSG00000189376,ENSG00000116670,ENSG00000184154,ENSG00000072571,ENSG00000055163,ENSG00000185880,ENSG00000184640,ENSG00000090520,ENSG00000132386,ENSG00000049239,ENSG00000127774,ENSG00000123338,ENSG00000010270,ENSG00000109536,ENSG00000140450,ENSG00000171943,ENSG00000128272,ENSG00000148337,ENSG00000124688,ENSG00000168268,ENSG00000120709,ENSG00000142867,ENSG00000110852,ENSG00000111335,ENSG00000114126,ENSG00000160051,ENSG00000250486,ENSG00000143740,ENSG00000126432,ENSG00000124155,ENSG00000214022,ENSG00000146112,ENSG00000198736,ENSG00000145337,ENSG00000138646,ENSG00000049541,ENSG00000196834,ENSG00000175283,ENSG00000104738,ENSG00000119318,ENSG00000172531,ENSG00000168765,ENSG00000178691,ENSG00000129968,ENSG00000257390,ENSG00000153044,ENSG00000140284,ENSG00000137309,ENSG00000132321,ENSG00000006756,ENSG00000041357,ENSG00000125354,ENSG00000125870,ENSG00000254087,ENSG00000139998,ENSG00000160255,ENSG00000152601,ENSG00000189306,ENSG00000104472,ENSG00000067840,ENSG00000066583,ENSG00000092841,ENSG00000091127,ENSG00000213366,ENSG00000140319,ENSG00000182628,ENSG00000111796,ENSG00000177076,ENSG00000137310,ENSG00000155660,ENSG00000101082,ENSG00000164576,ENSG00000131019,ENSG00000197409,ENSG00000172667,ENSG00000131873,ENSG00000173660,ENSG00000137312,ENSG00000198851,ENSG00000196839,ENSG00000132388,ENSG00000143321,ENSG00000089693,ENSG00000155090,ENSG00000148218,ENSG00000242574,ENSG00000147168,ENSG00000203950,ENSG00000134690,ENSG00000184575,ENSG00000177674,ENSG00000103489,ENSG00000135960,ENSG00000011007,ENSG00000154518,ENSG00000028137,ENSG00000160753,ENSG00000178685,ENSG00000169223,ENSG00000132256,ENSG00000147889,ENSG00000139926,ENSG00000140575,ENSG00000137193,ENSG00000146859,ENSG00000160404,ENSG00000111450,ENSG00000155096,ENSG00000175104,ENSG00000078124,ENSG00000196642,ENSG00000110218,ENSG00000169554,ENSG00000102053,ENSG00000127084,ENSG00000113387,ENSG00000166794,ENSG00000114631,ENSG00000111859,ENSG00000147180,ENSG00000170485,ENSG00000130818,ENSG00000081985 |
| GO:0001730 | 2’-5’-oligoadenylate synthetase activity | 0.0035366 | 3 | 718 | 3 | 0.0041783 | 1.0000000 | GO:MF | ENSG00000089127,ENSG00000111331,ENSG00000111335 |
| GO:0015037 | peptide disulfide oxidoreductase activity | 0.0051977 | 13 | 718 | 5 | 0.0069638 | 0.3846154 | GO:MF | ENSG00000143870,ENSG00000167004,ENSG00000023572,ENSG00000104687,ENSG00000155660 |
| GO:0003725 | double-stranded RNA binding | 0.0075755 | 74 | 718 | 11 | 0.0153203 | 0.1486486 | GO:MF | ENSG00000072110,ENSG00000135114,ENSG00000055332,ENSG00000123416,ENSG00000089127,ENSG00000147065,ENSG00000111331,ENSG00000196449,ENSG00000115267,ENSG00000111335,ENSG00000152601 |
| GO:0015036 | disulfide oxidoreductase activity | 0.0075755 | 40 | 718 | 8 | 0.0111421 | 0.2000000 | GO:MF | ENSG00000142669,ENSG00000143870,ENSG00000167004,ENSG00000023572,ENSG00000104687,ENSG00000139921,ENSG00000198843,ENSG00000155660 |
| GO:0019900 | kinase binding | 0.0083846 | 741 | 718 | 50 | 0.0696379 | 0.0674764 | GO:MF | ENSG00000113721,ENSG00000117281,ENSG00000155657,ENSG00000160014,ENSG00000164111,ENSG00000196924,ENSG00000118193,ENSG00000112029,ENSG00000167461,ENSG00000138160,ENSG00000165617,ENSG00000111206,ENSG00000179051,ENSG00000204397,ENSG00000100749,ENSG00000132646,ENSG00000116288,ENSG00000175793,ENSG00000143543,ENSG00000188191,ENSG00000187446,ENSG00000117394,ENSG00000152969,ENSG00000153094,ENSG00000132274,ENSG00000073803,ENSG00000147065,ENSG00000166974,ENSG00000118971,ENSG00000198821,ENSG00000067560,ENSG00000114166,ENSG00000075340,ENSG00000131747,ENSG00000070831,ENSG00000075624,ENSG00000096968,ENSG00000127666,ENSG00000138617,ENSG00000116670,ENSG00000128272,ENSG00000142867,ENSG00000160255,ENSG00000198851,ENSG00000132256,ENSG00000147889,ENSG00000140575,ENSG00000175104,ENSG00000111859,ENSG00000081985 |
| KEGG:04612 | Antigen processing and presentation | 0.0000000 | 69 | 362 | 24 | 0.0662983 | 0.3478261 | KEGG | ENSG00000179344,ENSG00000204267,ENSG00000196126,ENSG00000092010,ENSG00000179218,ENSG00000231925,ENSG00000019582,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000167004,ENSG00000111537,ENSG00000232810,ENSG00000134539,ENSG00000153563,ENSG00000172116,ENSG00000044574,ENSG00000166710,ENSG00000163131,ENSG00000204642,ENSG00000204592,ENSG00000179583,ENSG00000127022,ENSG00000242574 |
| KEGG:05169 | Epstein-Barr virus infection | 0.0000000 | 197 | 362 | 33 | 0.0911602 | 0.1675127 | KEGG | ENSG00000179344,ENSG00000204267,ENSG00000196126,ENSG00000179218,ENSG00000231925,ENSG00000115415,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000160654,ENSG00000167004,ENSG00000232810,ENSG00000005844,ENSG00000055332,ENSG00000153094,ENSG00000089127,ENSG00000007968,ENSG00000166710,ENSG00000118971,ENSG00000111331,ENSG00000198821,ENSG00000213928,ENSG00000185507,ENSG00000204642,ENSG00000204592,ENSG00000167286,ENSG00000187608,ENSG00000172936,ENSG00000111335,ENSG00000254087,ENSG00000198851,ENSG00000242574,ENSG00000175104 |
| KEGG:04658 | Th1 and Th2 cell differentiation | 0.0000002 | 89 | 362 | 20 | 0.0552486 | 0.2247191 | KEGG | ENSG00000179344,ENSG00000196126,ENSG00000073861,ENSG00000115415,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000160654,ENSG00000096996,ENSG00000111537,ENSG00000148400,ENSG00000100385,ENSG00000184916,ENSG00000198821,ENSG00000167286,ENSG00000096968,ENSG00000198851,ENSG00000242574,ENSG00000147168,ENSG00000081985 |
| KEGG:05332 | Graft-versus-host disease | 0.0000002 | 36 | 362 | 13 | 0.0359116 | 0.3611111 | KEGG | ENSG00000100453,ENSG00000179344,ENSG00000196126,ENSG00000117560,ENSG00000223865,ENSG00000231389,ENSG00000111537,ENSG00000232810,ENSG00000134539,ENSG00000180644,ENSG00000204642,ENSG00000204592,ENSG00000242574 |
| KEGG:05330 | Allograft rejection | 0.0000011 | 34 | 362 | 12 | 0.0331492 | 0.3529412 | KEGG | ENSG00000100453,ENSG00000179344,ENSG00000196126,ENSG00000117560,ENSG00000223865,ENSG00000231389,ENSG00000111537,ENSG00000232810,ENSG00000180644,ENSG00000204642,ENSG00000204592,ENSG00000242574 |
| KEGG:05164 | Influenza A | 0.0000020 | 167 | 362 | 26 | 0.0718232 | 0.1556886 | KEGG | ENSG00000179344,ENSG00000196126,ENSG00000117560,ENSG00000115415,ENSG00000223865,ENSG00000231389,ENSG00000111537,ENSG00000232810,ENSG00000103769,ENSG00000134321,ENSG00000136436,ENSG00000055332,ENSG00000157601,ENSG00000089127,ENSG00000132661,ENSG00000111331,ENSG00000213928,ENSG00000185507,ENSG00000115267,ENSG00000172936,ENSG00000179583,ENSG00000075624,ENSG00000096968,ENSG00000127666,ENSG00000111335,ENSG00000242574 |
| KEGG:04659 | Th17 cell differentiation | 0.0000020 | 104 | 362 | 20 | 0.0552486 | 0.1923077 | KEGG | ENSG00000179344,ENSG00000196126,ENSG00000073861,ENSG00000159216,ENSG00000115415,ENSG00000223865,ENSG00000231389,ENSG00000105639,ENSG00000160654,ENSG00000137265,ENSG00000096996,ENSG00000111537,ENSG00000134352,ENSG00000100385,ENSG00000198821,ENSG00000167286,ENSG00000096968,ENSG00000198851,ENSG00000242574,ENSG00000147168 |
| KEGG:04940 | Type I diabetes mellitus | 0.0000054 | 40 | 362 | 12 | 0.0331492 | 0.3000000 | KEGG | ENSG00000100453,ENSG00000179344,ENSG00000196126,ENSG00000117560,ENSG00000223865,ENSG00000231389,ENSG00000111537,ENSG00000232810,ENSG00000180644,ENSG00000204642,ENSG00000204592,ENSG00000242574 |
| KEGG:05166 | Human T-cell leukemia virus 1 infection | 0.0000067 | 216 | 362 | 29 | 0.0801105 | 0.1342593 | KEGG | ENSG00000179344,ENSG00000196126,ENSG00000179218,ENSG00000223865,ENSG00000231389,ENSG00000156970,ENSG00000105639,ENSG00000160654,ENSG00000232810,ENSG00000005844,ENSG00000117394,ENSG00000213281,ENSG00000007968,ENSG00000166710,ENSG00000118971,ENSG00000100385,ENSG00000114166,ENSG00000204642,ENSG00000122877,ENSG00000204592,ENSG00000167286,ENSG00000162104,ENSG00000127022,ENSG00000128272,ENSG00000160255,ENSG00000198851,ENSG00000242574,ENSG00000147168,ENSG00000147889 |
| KEGG:05170 | Human immunodeficiency virus 1 infection | 0.0000114 | 210 | 362 | 28 | 0.0773481 | 0.1333333 | KEGG | ENSG00000204267,ENSG00000179218,ENSG00000231925,ENSG00000117560,ENSG00000160014,ENSG00000186469,ENSG00000160654,ENSG00000167004,ENSG00000172757,ENSG00000232810,ENSG00000170312,ENSG00000239713,ENSG00000065135,ENSG00000213281,ENSG00000072958,ENSG00000166710,ENSG00000129007,ENSG00000198821,ENSG00000100298,ENSG00000204642,ENSG00000204592,ENSG00000167286,ENSG00000172936,ENSG00000128394,ENSG00000198851,ENSG00000028137,ENSG00000132256,ENSG00000175104 |
| KEGG:05140 | Leishmaniasis | 0.0001178 | 72 | 362 | 14 | 0.0386740 | 0.1944444 | KEGG | ENSG00000179344,ENSG00000196126,ENSG00000203747,ENSG00000115415,ENSG00000223865,ENSG00000231389,ENSG00000150093,ENSG00000111537,ENSG00000232810,ENSG00000172936,ENSG00000096968,ENSG00000160255,ENSG00000242574,ENSG00000175104 |
| KEGG:05152 | Tuberculosis | 0.0001268 | 175 | 362 | 23 | 0.0635359 | 0.1314286 | KEGG | ENSG00000179344,ENSG00000196126,ENSG00000019582,ENSG00000203747,ENSG00000160014,ENSG00000115415,ENSG00000223865,ENSG00000231389,ENSG00000117984,ENSG00000111537,ENSG00000232810,ENSG00000130592,ENSG00000129007,ENSG00000158869,ENSG00000163131,ENSG00000067560,ENSG00000172936,ENSG00000179583,ENSG00000096968,ENSG00000142867,ENSG00000160255,ENSG00000242574,ENSG00000175104 |
| KEGG:05162 | Measles | 0.0001268 | 138 | 362 | 20 | 0.0552486 | 0.1449275 | KEGG | ENSG00000117560,ENSG00000115415,ENSG00000105639,ENSG00000160654,ENSG00000055332,ENSG00000157601,ENSG00000089127,ENSG00000147065,ENSG00000118971,ENSG00000111331,ENSG00000100385,ENSG00000213928,ENSG00000185507,ENSG00000115267,ENSG00000167286,ENSG00000172936,ENSG00000111335,ENSG00000198851,ENSG00000147168,ENSG00000175104 |
| KEGG:05416 | Viral myocarditis | 0.0001572 | 56 | 362 | 12 | 0.0331492 | 0.2142857 | KEGG | ENSG00000179344,ENSG00000196126,ENSG00000223865,ENSG00000231389,ENSG00000005844,ENSG00000180644,ENSG00000075151,ENSG00000204642,ENSG00000204592,ENSG00000075624,ENSG00000160255,ENSG00000242574 |
| KEGG:05320 | Autoimmune thyroid disease | 0.0002203 | 49 | 362 | 11 | 0.0303867 | 0.2244898 | KEGG | ENSG00000100453,ENSG00000179344,ENSG00000196126,ENSG00000163599,ENSG00000117560,ENSG00000223865,ENSG00000231389,ENSG00000180644,ENSG00000204642,ENSG00000204592,ENSG00000242574 |
| KEGG:05321 | Inflammatory bowel disease (IBD) | 0.0004135 | 62 | 362 | 12 | 0.0331492 | 0.1935484 | KEGG | ENSG00000179344,ENSG00000196126,ENSG00000073861,ENSG00000115415,ENSG00000223865,ENSG00000231389,ENSG00000096996,ENSG00000111537,ENSG00000232810,ENSG00000242574,ENSG00000147168,ENSG00000081985 |
| KEGG:05340 | Primary immunodeficiency | 0.0005911 | 37 | 362 | 9 | 0.0248619 | 0.2432432 | KEGG | ENSG00000204267,ENSG00000105639,ENSG00000153563,ENSG00000172116,ENSG00000167286,ENSG00000179583,ENSG00000198851,ENSG00000196839,ENSG00000147168 |
| KEGG:04514 | Cell adhesion molecules (CAMs) | 0.0005911 | 144 | 362 | 19 | 0.0524862 | 0.1319444 | KEGG | ENSG00000179344,ENSG00000196126,ENSG00000163599,ENSG00000173482,ENSG00000091129,ENSG00000223865,ENSG00000231389,ENSG00000150093,ENSG00000139626,ENSG00000153563,ENSG00000005844,ENSG00000073008,ENSG00000172116,ENSG00000013725,ENSG00000149294,ENSG00000204642,ENSG00000204592,ENSG00000160255,ENSG00000242574 |
| KEGG:05145 | Toxoplasmosis | 0.0006062 | 109 | 362 | 16 | 0.0441989 | 0.1467890 | KEGG | ENSG00000179344,ENSG00000196126,ENSG00000130164,ENSG00000115415,ENSG00000223865,ENSG00000231389,ENSG00000150093,ENSG00000111537,ENSG00000232810,ENSG00000108179,ENSG00000065135,ENSG00000172936,ENSG00000179583,ENSG00000096968,ENSG00000242574,ENSG00000175104 |
| KEGG:04810 | Regulation of actin cytoskeleton | 0.0006578 | 212 | 362 | 24 | 0.0662983 | 0.1132075 | KEGG | ENSG00000113721,ENSG00000072110,ENSG00000156886,ENSG00000150093,ENSG00000172757,ENSG00000139626,ENSG00000108518,ENSG00000005844,ENSG00000130402,ENSG00000213281,ENSG00000111229,ENSG00000147065,ENSG00000129675,ENSG00000131504,ENSG00000067560,ENSG00000133026,ENSG00000070831,ENSG00000075624,ENSG00000055163,ENSG00000123338,ENSG00000172531,ENSG00000160255,ENSG00000140575,ENSG00000127084 |
| KEGG:05160 | Hepatitis C | 0.0013584 | 155 | 362 | 19 | 0.0524862 | 0.1225806 | KEGG | ENSG00000117560,ENSG00000130164,ENSG00000115415,ENSG00000111537,ENSG00000232810,ENSG00000134308,ENSG00000134321,ENSG00000055332,ENSG00000213281,ENSG00000157601,ENSG00000089127,ENSG00000007968,ENSG00000185745,ENSG00000111331,ENSG00000213928,ENSG00000185507,ENSG00000127666,ENSG00000111335,ENSG00000175104 |
| KEGG:04145 | Phagosome | 0.0020019 | 147 | 362 | 18 | 0.0497238 | 0.1224490 | KEGG | ENSG00000179344,ENSG00000204267,ENSG00000196126,ENSG00000179218,ENSG00000203747,ENSG00000223865,ENSG00000231389,ENSG00000150093,ENSG00000196230,ENSG00000123416,ENSG00000171130,ENSG00000163131,ENSG00000204642,ENSG00000204592,ENSG00000075624,ENSG00000127022,ENSG00000160255,ENSG00000242574 |
| KEGG:04650 | Natural killer cell mediated cytotoxicity | 0.0021117 | 123 | 362 | 16 | 0.0441989 | 0.1300813 | KEGG | ENSG00000100453,ENSG00000117560,ENSG00000203747,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000134539,ENSG00000005844,ENSG00000180644,ENSG00000122223,ENSG00000213281,ENSG00000158869,ENSG00000198821,ENSG00000204592,ENSG00000160255,ENSG00000131019 |
| KEGG:05133 | Pertussis | 0.0021117 | 76 | 362 | 12 | 0.0331492 | 0.1578947 | KEGG | ENSG00000125347,ENSG00000160014,ENSG00000150093,ENSG00000172757,ENSG00000232810,ENSG00000065135,ENSG00000129007,ENSG00000067560,ENSG00000172936,ENSG00000127666,ENSG00000160255,ENSG00000175104 |
| KEGG:05310 | Asthma | 0.0021117 | 27 | 362 | 7 | 0.0193370 | 0.2592593 | KEGG | ENSG00000179344,ENSG00000196126,ENSG00000223865,ENSG00000231389,ENSG00000232810,ENSG00000158869,ENSG00000242574 |
| KEGG:04621 | NOD-like receptor signaling pathway | 0.0022438 | 177 | 362 | 20 | 0.0552486 | 0.1129944 | KEGG | ENSG00000154451,ENSG00000162654,ENSG00000115415,ENSG00000213512,ENSG00000232810,ENSG00000117228,ENSG00000204397,ENSG00000117226,ENSG00000249437,ENSG00000089127,ENSG00000196954,ENSG00000111331,ENSG00000067560,ENSG00000213928,ENSG00000185507,ENSG00000172936,ENSG00000127666,ENSG00000111335,ENSG00000175104,ENSG00000110218 |
| KEGG:05132 | Salmonella infection | 0.0040975 | 214 | 362 | 22 | 0.0607735 | 0.1028037 | KEGG | ENSG00000196924,ENSG00000138795,ENSG00000232810,ENSG00000111640,ENSG00000108518,ENSG00000249437,ENSG00000215305,ENSG00000111229,ENSG00000166598,ENSG00000196954,ENSG00000168421,ENSG00000067560,ENSG00000133026,ENSG00000178996,ENSG00000070831,ENSG00000172936,ENSG00000075624,ENSG00000165527,ENSG00000055163,ENSG00000123338,ENSG00000092841,ENSG00000175104 |
| KEGG:04520 | Adherens junction | 0.0041391 | 71 | 362 | 11 | 0.0303867 | 0.1549296 | KEGG | ENSG00000072110,ENSG00000173482,ENSG00000138795,ENSG00000130402,ENSG00000067560,ENSG00000143727,ENSG00000141736,ENSG00000070831,ENSG00000075624,ENSG00000117155,ENSG00000140575 |
| KEGG:04640 | Hematopoietic cell lineage | 0.0042678 | 95 | 362 | 13 | 0.0359116 | 0.1368421 | KEGG | ENSG00000004468,ENSG00000179344,ENSG00000196126,ENSG00000223865,ENSG00000231389,ENSG00000160654,ENSG00000232810,ENSG00000153563,ENSG00000172116,ENSG00000110448,ENSG00000167286,ENSG00000198851,ENSG00000242574 |
| KEGG:00480 | Glutathione metabolism | 0.0075347 | 54 | 362 | 9 | 0.0248619 | 0.1666667 | KEGG | ENSG00000134184,ENSG00000182054,ENSG00000171848,ENSG00000104687,ENSG00000134202,ENSG00000006625,ENSG00000002549,ENSG00000168765,ENSG00000213366 |
| KEGG:04660 | T cell receptor signaling pathway | 0.0084811 | 103 | 362 | 13 | 0.0359116 | 0.1262136 | KEGG | ENSG00000163599,ENSG00000160654,ENSG00000111537,ENSG00000232810,ENSG00000153563,ENSG00000172116,ENSG00000213281,ENSG00000198821,ENSG00000067560,ENSG00000167286,ENSG00000070831,ENSG00000142867,ENSG00000198851 |
| KEGG:05203 | Viral carcinogenesis | 0.0084811 | 199 | 362 | 20 | 0.0552486 | 0.1005025 | KEGG | ENSG00000072110,ENSG00000105639,ENSG00000134308,ENSG00000134352,ENSG00000130402,ENSG00000170312,ENSG00000055332,ENSG00000213281,ENSG00000118971,ENSG00000067560,ENSG00000213928,ENSG00000114166,ENSG00000185507,ENSG00000204642,ENSG00000122877,ENSG00000204592,ENSG00000070831,ENSG00000128272,ENSG00000254087,ENSG00000147889 |
| KEGG:05167 | Kaposi sarcoma-associated herpesvirus infection | 0.0089879 | 186 | 362 | 19 | 0.0524862 | 0.1021505 | KEGG | ENSG00000160014,ENSG00000115415,ENSG00000186469,ENSG00000170315,ENSG00000134352,ENSG00000055332,ENSG00000213281,ENSG00000159200,ENSG00000007968,ENSG00000163823,ENSG00000129007,ENSG00000213928,ENSG00000185507,ENSG00000204642,ENSG00000204592,ENSG00000096968,ENSG00000127666,ENSG00000110852,ENSG00000254087 |
| REAC:R-HSA-913531 | Interferon Signaling | 0.0000000 | 193 | 480 | 49 | 0.1020833 | 0.2538860 | REAC | ENSG00000156587,ENSG00000119922,ENSG00000196126,ENSG00000132530,ENSG00000125347,ENSG00000126709,ENSG00000154451,ENSG00000162654,ENSG00000196735,ENSG00000115415,ENSG00000119917,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000142089,ENSG00000196924,ENSG00000137265,ENSG00000111537,ENSG00000117228,ENSG00000117226,ENSG00000185201,ENSG00000135114,ENSG00000134321,ENSG00000204264,ENSG00000185885,ENSG00000165949,ENSG00000055332,ENSG00000157601,ENSG00000089127,ENSG00000116030,ENSG00000132274,ENSG00000166710,ENSG00000185745,ENSG00000111331,ENSG00000125148,ENSG00000075151,ENSG00000213928,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000204592,ENSG00000132182,ENSG00000187608,ENSG00000179583,ENSG00000096968,ENSG00000111335,ENSG00000138646,ENSG00000132256 |
| REAC:R-HSA-168256 | Immune System | 0.0000000 | 2147 | 480 | 175 | 0.3645833 | 0.0815091 | REAC | ENSG00000172057,ENSG00000164308,ENSG00000156587,ENSG00000119922,ENSG00000204267,ENSG00000113721,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000163599,ENSG00000132530,ENSG00000125347,ENSG00000100321,ENSG00000179218,ENSG00000115523,ENSG00000126709,ENSG00000135077,ENSG00000154451,ENSG00000162654,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000117560,ENSG00000072135,ENSG00000203747,ENSG00000115415,ENSG00000119917,ENSG00000155629,ENSG00000100911,ENSG00000113368,ENSG00000177156,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000142089,ENSG00000160654,ENSG00000167004,ENSG00000196924,ENSG00000137265,ENSG00000117984,ENSG00000127947,ENSG00000186470,ENSG00000150093,ENSG00000136167,ENSG00000138160,ENSG00000096996,ENSG00000172757,ENSG00000111537,ENSG00000189430,ENSG00000232810,ENSG00000134539,ENSG00000117228,ENSG00000134352,ENSG00000139626,ENSG00000153563,ENSG00000117226,ENSG00000005844,ENSG00000185201,ENSG00000196230,ENSG00000134765,ENSG00000073008,ENSG00000135114,ENSG00000134321,ENSG00000137563,ENSG00000138642,ENSG00000204264,ENSG00000167618,ENSG00000185885,ENSG00000185651,ENSG00000172116,ENSG00000165949,ENSG00000055332,ENSG00000123416,ENSG00000213445,ENSG00000213281,ENSG00000123131,ENSG00000157601,ENSG00000089127,ENSG00000171130,ENSG00000089685,ENSG00000044574,ENSG00000116030,ENSG00000064666,ENSG00000072958,ENSG00000132274,ENSG00000166710,ENSG00000211810,ENSG00000111229,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000154001,ENSG00000241258,ENSG00000138071,ENSG00000166598,ENSG00000131236,ENSG00000021355,ENSG00000196954,ENSG00000183475,ENSG00000111331,ENSG00000105220,ENSG00000181467,ENSG00000158869,ENSG00000181191,ENSG00000100299,ENSG00000163131,ENSG00000100385,ENSG00000125148,ENSG00000131504,ENSG00000075151,ENSG00000011485,ENSG00000067560,ENSG00000213928,ENSG00000172794,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000115267,ENSG00000168961,ENSG00000148175,ENSG00000184887,ENSG00000141736,ENSG00000204592,ENSG00000132182,ENSG00000118564,ENSG00000167286,ENSG00000187608,ENSG00000157873,ENSG00000042753,ENSG00000070831,ENSG00000172936,ENSG00000179583,ENSG00000171302,ENSG00000147234,ENSG00000132670,ENSG00000075624,ENSG00000096968,ENSG00000079999,ENSG00000127666,ENSG00000139370,ENSG00000127022,ENSG00000026751,ENSG00000055163,ENSG00000185880,ENSG00000123338,ENSG00000142867,ENSG00000110852,ENSG00000111335,ENSG00000138646,ENSG00000140284,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000140319,ENSG00000111796,ENSG00000127951,ENSG00000131019,ENSG00000197409,ENSG00000198851,ENSG00000132388,ENSG00000148218,ENSG00000242574,ENSG00000147168,ENSG00000135960,ENSG00000028137,ENSG00000132256,ENSG00000140575,ENSG00000137193,ENSG00000175104,ENSG00000110218,ENSG00000081985 |
| REAC:R-HSA-877300 | Interferon gamma signaling | 0.0000000 | 87 | 480 | 28 | 0.0583333 | 0.3218391 | REAC | ENSG00000196126,ENSG00000125347,ENSG00000154451,ENSG00000162654,ENSG00000196735,ENSG00000223865,ENSG00000231389,ENSG00000213512,ENSG00000137265,ENSG00000111537,ENSG00000117228,ENSG00000117226,ENSG00000135114,ENSG00000089127,ENSG00000116030,ENSG00000132274,ENSG00000166710,ENSG00000111331,ENSG00000125148,ENSG00000213928,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000204592,ENSG00000179583,ENSG00000096968,ENSG00000111335,ENSG00000132256 |
| REAC:R-HSA-1280215 | Cytokine Signaling in Immune system | 0.0000000 | 831 | 480 | 93 | 0.1937500 | 0.1119134 | REAC | ENSG00000156587,ENSG00000119922,ENSG00000113721,ENSG00000196126,ENSG00000092010,ENSG00000132530,ENSG00000125347,ENSG00000126709,ENSG00000135077,ENSG00000154451,ENSG00000162654,ENSG00000196735,ENSG00000117560,ENSG00000072135,ENSG00000115415,ENSG00000119917,ENSG00000100911,ENSG00000113368,ENSG00000177156,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000213512,ENSG00000105639,ENSG00000142089,ENSG00000196924,ENSG00000137265,ENSG00000127947,ENSG00000150093,ENSG00000136167,ENSG00000096996,ENSG00000172757,ENSG00000111537,ENSG00000232810,ENSG00000117228,ENSG00000134352,ENSG00000117226,ENSG00000185201,ENSG00000135114,ENSG00000134321,ENSG00000204264,ENSG00000185885,ENSG00000165949,ENSG00000055332,ENSG00000213281,ENSG00000157601,ENSG00000089127,ENSG00000089685,ENSG00000116030,ENSG00000064666,ENSG00000132274,ENSG00000166710,ENSG00000185745,ENSG00000163823,ENSG00000147065,ENSG00000154001,ENSG00000166598,ENSG00000111331,ENSG00000100385,ENSG00000125148,ENSG00000075151,ENSG00000011485,ENSG00000213928,ENSG00000149294,ENSG00000185507,ENSG00000204642,ENSG00000168961,ENSG00000141736,ENSG00000204592,ENSG00000132182,ENSG00000187608,ENSG00000157873,ENSG00000070831,ENSG00000172936,ENSG00000179583,ENSG00000132670,ENSG00000075624,ENSG00000096968,ENSG00000127022,ENSG00000111335,ENSG00000138646,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000197409,ENSG00000147168,ENSG00000135960,ENSG00000028137,ENSG00000132256,ENSG00000140575,ENSG00000137193,ENSG00000175104,ENSG00000081985 |
| REAC:R-HSA-909733 | Interferon alpha/beta signaling | 0.0000000 | 67 | 480 | 23 | 0.0479167 | 0.3432836 | REAC | ENSG00000119922,ENSG00000132530,ENSG00000125347,ENSG00000126709,ENSG00000119917,ENSG00000142089,ENSG00000137265,ENSG00000185201,ENSG00000135114,ENSG00000134321,ENSG00000204264,ENSG00000185885,ENSG00000165949,ENSG00000157601,ENSG00000089127,ENSG00000185745,ENSG00000111331,ENSG00000213928,ENSG00000185507,ENSG00000204642,ENSG00000204592,ENSG00000187608,ENSG00000111335 |
| REAC:R-HSA-1280218 | Adaptive Immune System | 0.0000009 | 799 | 480 | 73 | 0.1520833 | 0.0913642 | REAC | ENSG00000164308,ENSG00000156587,ENSG00000204267,ENSG00000117281,ENSG00000196126,ENSG00000092010,ENSG00000163599,ENSG00000179218,ENSG00000163840,ENSG00000089692,ENSG00000196735,ENSG00000231925,ENSG00000019582,ENSG00000203747,ENSG00000155629,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000160654,ENSG00000167004,ENSG00000117984,ENSG00000186470,ENSG00000150093,ENSG00000138160,ENSG00000189430,ENSG00000134539,ENSG00000139626,ENSG00000153563,ENSG00000005844,ENSG00000073008,ENSG00000138642,ENSG00000204264,ENSG00000167618,ENSG00000185885,ENSG00000185651,ENSG00000172116,ENSG00000123416,ENSG00000213445,ENSG00000213281,ENSG00000044574,ENSG00000072958,ENSG00000166710,ENSG00000211810,ENSG00000154001,ENSG00000183475,ENSG00000181191,ENSG00000163131,ENSG00000204642,ENSG00000184887,ENSG00000204592,ENSG00000118564,ENSG00000167286,ENSG00000157873,ENSG00000042753,ENSG00000070831,ENSG00000172936,ENSG00000079999,ENSG00000127022,ENSG00000026751,ENSG00000185880,ENSG00000142867,ENSG00000110852,ENSG00000138646,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000111796,ENSG00000131019,ENSG00000198851,ENSG00000132388,ENSG00000242574,ENSG00000175104 |
| REAC:R-HSA-447115 | Interleukin-12 family signaling | 0.0000040 | 57 | 480 | 15 | 0.0312500 | 0.2631579 | REAC | ENSG00000115415,ENSG00000100911,ENSG00000113368,ENSG00000177156,ENSG00000136167,ENSG00000096996,ENSG00000172757,ENSG00000111537,ENSG00000134352,ENSG00000064666,ENSG00000147065,ENSG00000070831,ENSG00000096968,ENSG00000127022,ENSG00000081985 |
| REAC:R-HSA-983170 | Antigen Presentation: Folding, assembly and peptide loading of class I MHC | 0.0000096 | 25 | 480 | 10 | 0.0208333 | 0.4000000 | REAC | ENSG00000164308,ENSG00000204267,ENSG00000179218,ENSG00000231925,ENSG00000167004,ENSG00000044574,ENSG00000166710,ENSG00000204642,ENSG00000204592,ENSG00000127022 |
| REAC:R-HSA-1640170 | Cell Cycle | 0.0000103 | 632 | 480 | 59 | 0.1229167 | 0.0933544 | REAC | ENSG00000092010,ENSG00000117724,ENSG00000123485,ENSG00000100911,ENSG00000113368,ENSG00000101057,ENSG00000170315,ENSG00000156970,ENSG00000171848,ENSG00000112029,ENSG00000167461,ENSG00000111206,ENSG00000179051,ENSG00000134308,ENSG00000176890,ENSG00000100749,ENSG00000132646,ENSG00000196230,ENSG00000175793,ENSG00000100918,ENSG00000204264,ENSG00000131018,ENSG00000188312,ENSG00000170312,ENSG00000092853,ENSG00000123416,ENSG00000119335,ENSG00000089685,ENSG00000163041,ENSG00000181938,ENSG00000116030,ENSG00000007968,ENSG00000204899,ENSG00000154001,ENSG00000118971,ENSG00000129534,ENSG00000093009,ENSG00000122952,ENSG00000143228,ENSG00000113810,ENSG00000131747,ENSG00000132182,ENSG00000174371,ENSG00000176101,ENSG00000152253,ENSG00000096968,ENSG00000136824,ENSG00000109805,ENSG00000072571,ENSG00000114126,ENSG00000049541,ENSG00000104738,ENSG00000153044,ENSG00000041357,ENSG00000254087,ENSG00000182628,ENSG00000197409,ENSG00000134690,ENSG00000147889 |
| REAC:R-HSA-69278 | Cell Cycle, Mitotic | 0.0000619 | 527 | 480 | 50 | 0.1041667 | 0.0948767 | REAC | ENSG00000092010,ENSG00000117724,ENSG00000100911,ENSG00000113368,ENSG00000101057,ENSG00000170315,ENSG00000156970,ENSG00000171848,ENSG00000112029,ENSG00000167461,ENSG00000111206,ENSG00000179051,ENSG00000176890,ENSG00000100749,ENSG00000132646,ENSG00000196230,ENSG00000204264,ENSG00000188312,ENSG00000170312,ENSG00000123416,ENSG00000119335,ENSG00000089685,ENSG00000163041,ENSG00000181938,ENSG00000007968,ENSG00000204899,ENSG00000154001,ENSG00000118971,ENSG00000093009,ENSG00000122952,ENSG00000143228,ENSG00000113810,ENSG00000131747,ENSG00000132182,ENSG00000176101,ENSG00000152253,ENSG00000096968,ENSG00000136824,ENSG00000109805,ENSG00000072571,ENSG00000114126,ENSG00000049541,ENSG00000104738,ENSG00000153044,ENSG00000041357,ENSG00000254087,ENSG00000182628,ENSG00000197409,ENSG00000134690,ENSG00000147889 |
| REAC:R-HSA-9020591 | Interleukin-12 signaling | 0.0000952 | 47 | 480 | 12 | 0.0250000 | 0.2553191 | REAC | ENSG00000100911,ENSG00000113368,ENSG00000177156,ENSG00000136167,ENSG00000096996,ENSG00000172757,ENSG00000111537,ENSG00000064666,ENSG00000147065,ENSG00000070831,ENSG00000096968,ENSG00000081985 |
| REAC:R-HSA-202430 | Translocation of ZAP-70 to Immunological synapse | 0.0001422 | 20 | 480 | 8 | 0.0166667 | 0.4000000 | REAC | ENSG00000196126,ENSG00000196735,ENSG00000223865,ENSG00000231389,ENSG00000160654,ENSG00000211810,ENSG00000167286,ENSG00000198851 |
| REAC:R-HSA-198933 | Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | 0.0001948 | 181 | 480 | 24 | 0.0500000 | 0.1325967 | REAC | ENSG00000117281,ENSG00000203747,ENSG00000160654,ENSG00000150093,ENSG00000189430,ENSG00000134539,ENSG00000139626,ENSG00000153563,ENSG00000005844,ENSG00000073008,ENSG00000167618,ENSG00000185885,ENSG00000172116,ENSG00000166710,ENSG00000211810,ENSG00000204642,ENSG00000204592,ENSG00000167286,ENSG00000026751,ENSG00000110852,ENSG00000160255,ENSG00000111796,ENSG00000131019,ENSG00000198851 |
| REAC:R-HSA-1169410 | Antiviral mechanism by IFN-stimulated genes | 0.0001948 | 79 | 480 | 15 | 0.0312500 | 0.1898734 | REAC | ENSG00000156587,ENSG00000115415,ENSG00000170315,ENSG00000196924,ENSG00000135114,ENSG00000055332,ENSG00000157601,ENSG00000089127,ENSG00000185745,ENSG00000111331,ENSG00000075151,ENSG00000132182,ENSG00000187608,ENSG00000111335,ENSG00000138646 |
| REAC:R-HSA-202427 | Phosphorylation of CD3 and TCR zeta chains | 0.0003925 | 23 | 480 | 8 | 0.0166667 | 0.3478261 | REAC | ENSG00000196126,ENSG00000196735,ENSG00000223865,ENSG00000231389,ENSG00000160654,ENSG00000211810,ENSG00000167286,ENSG00000198851 |
| REAC:R-HSA-194315 | Signaling by Rho GTPases | 0.0004822 | 449 | 480 | 42 | 0.0875000 | 0.0935412 | REAC | ENSG00000198826,ENSG00000117724,ENSG00000156970,ENSG00000196924,ENSG00000118193,ENSG00000150093,ENSG00000173848,ENSG00000172757,ENSG00000179051,ENSG00000134308,ENSG00000108518,ENSG00000213390,ENSG00000175793,ENSG00000188312,ENSG00000071205,ENSG00000123416,ENSG00000089685,ENSG00000163041,ENSG00000111229,ENSG00000154001,ENSG00000138071,ENSG00000111348,ENSG00000129675,ENSG00000122952,ENSG00000143228,ENSG00000168421,ENSG00000134909,ENSG00000131504,ENSG00000067560,ENSG00000133026,ENSG00000070831,ENSG00000152253,ENSG00000075624,ENSG00000055163,ENSG00000123338,ENSG00000153044,ENSG00000092841,ENSG00000182628,ENSG00000197409,ENSG00000134690,ENSG00000140575,ENSG00000127084 |
| REAC:R-HSA-389948 | PD-1 signaling | 0.0004991 | 24 | 480 | 8 | 0.0166667 | 0.3333333 | REAC | ENSG00000196126,ENSG00000196735,ENSG00000223865,ENSG00000231389,ENSG00000160654,ENSG00000211810,ENSG00000167286,ENSG00000198851 |
| REAC:R-HSA-195258 | RHO GTPase Effectors | 0.0005341 | 319 | 480 | 33 | 0.0687500 | 0.1034483 | REAC | ENSG00000117724,ENSG00000156970,ENSG00000196924,ENSG00000118193,ENSG00000150093,ENSG00000172757,ENSG00000179051,ENSG00000134308,ENSG00000108518,ENSG00000175793,ENSG00000188312,ENSG00000123416,ENSG00000089685,ENSG00000163041,ENSG00000111229,ENSG00000154001,ENSG00000138071,ENSG00000122952,ENSG00000143228,ENSG00000131504,ENSG00000067560,ENSG00000133026,ENSG00000070831,ENSG00000152253,ENSG00000075624,ENSG00000055163,ENSG00000123338,ENSG00000153044,ENSG00000092841,ENSG00000182628,ENSG00000197409,ENSG00000134690,ENSG00000140575 |
| REAC:R-HSA-388841 | Costimulation by the CD28 family | 0.0005341 | 67 | 480 | 13 | 0.0270833 | 0.1940299 | REAC | ENSG00000196126,ENSG00000163599,ENSG00000196735,ENSG00000223865,ENSG00000231389,ENSG00000160654,ENSG00000211810,ENSG00000154001,ENSG00000167286,ENSG00000157873,ENSG00000070831,ENSG00000254087,ENSG00000198851 |
| REAC:R-HSA-5663220 | RHO GTPases Activate Formins | 0.0007042 | 136 | 480 | 19 | 0.0395833 | 0.1397059 | REAC | ENSG00000117724,ENSG00000156970,ENSG00000150093,ENSG00000179051,ENSG00000108518,ENSG00000188312,ENSG00000123416,ENSG00000089685,ENSG00000154001,ENSG00000122952,ENSG00000143228,ENSG00000131504,ENSG00000067560,ENSG00000070831,ENSG00000152253,ENSG00000075624,ENSG00000153044,ENSG00000182628,ENSG00000134690 |
| REAC:R-HSA-453279 | Mitotic G1 phase and G1/S transition | 0.0007042 | 148 | 480 | 20 | 0.0416667 | 0.1351351 | REAC | ENSG00000092010,ENSG00000100911,ENSG00000101057,ENSG00000170315,ENSG00000171848,ENSG00000112029,ENSG00000176890,ENSG00000132646,ENSG00000204264,ENSG00000170312,ENSG00000007968,ENSG00000118971,ENSG00000093009,ENSG00000131747,ENSG00000096968,ENSG00000114126,ENSG00000104738,ENSG00000041357,ENSG00000254087,ENSG00000147889 |
| REAC:R-HSA-8983711 | OAS antiviral response | 0.0012052 | 9 | 480 | 5 | 0.0104167 | 0.5555556 | REAC | ENSG00000196924,ENSG00000135114,ENSG00000089127,ENSG00000111331,ENSG00000111335 |
| REAC:R-HSA-202424 | Downstream TCR signaling | 0.0018106 | 98 | 480 | 15 | 0.0312500 | 0.1530612 | REAC | ENSG00000196126,ENSG00000092010,ENSG00000196735,ENSG00000100911,ENSG00000223865,ENSG00000231389,ENSG00000170315,ENSG00000160654,ENSG00000204264,ENSG00000211810,ENSG00000167286,ENSG00000142867,ENSG00000041357,ENSG00000198851,ENSG00000175104 |
| REAC:R-HSA-8950505 | Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | 0.0020474 | 38 | 480 | 9 | 0.0187500 | 0.2368421 | REAC | ENSG00000100911,ENSG00000113368,ENSG00000177156,ENSG00000136167,ENSG00000172757,ENSG00000111537,ENSG00000064666,ENSG00000147065,ENSG00000070831 |
| REAC:R-HSA-449147 | Signaling by Interleukins | 0.0026627 | 459 | 480 | 40 | 0.0833333 | 0.0871460 | REAC | ENSG00000092010,ENSG00000135077,ENSG00000117560,ENSG00000072135,ENSG00000115415,ENSG00000100911,ENSG00000113368,ENSG00000177156,ENSG00000170315,ENSG00000105639,ENSG00000137265,ENSG00000127947,ENSG00000150093,ENSG00000136167,ENSG00000096996,ENSG00000172757,ENSG00000111537,ENSG00000232810,ENSG00000134352,ENSG00000204264,ENSG00000089685,ENSG00000064666,ENSG00000163823,ENSG00000147065,ENSG00000166598,ENSG00000100385,ENSG00000168961,ENSG00000070831,ENSG00000172936,ENSG00000096968,ENSG00000127022,ENSG00000041357,ENSG00000254087,ENSG00000160255,ENSG00000197409,ENSG00000147168,ENSG00000028137,ENSG00000137193,ENSG00000175104,ENSG00000081985 |
| REAC:R-HSA-1236974 | ER-Phagosome pathway | 0.0041957 | 83 | 480 | 13 | 0.0270833 | 0.1566265 | REAC | ENSG00000204267,ENSG00000092010,ENSG00000179218,ENSG00000231925,ENSG00000100911,ENSG00000170315,ENSG00000167004,ENSG00000204264,ENSG00000166710,ENSG00000204642,ENSG00000204592,ENSG00000172936,ENSG00000041357 |
| REAC:R-HSA-202433 | Generation of second messenger molecules | 0.0051974 | 34 | 480 | 8 | 0.0166667 | 0.2352941 | REAC | ENSG00000196126,ENSG00000196735,ENSG00000223865,ENSG00000231389,ENSG00000160654,ENSG00000211810,ENSG00000167286,ENSG00000198851 |
| REAC:R-HSA-8984722 | Interleukin-35 Signalling | 0.0053125 | 12 | 480 | 5 | 0.0104167 | 0.4166667 | REAC | ENSG00000115415,ENSG00000134352,ENSG00000096968,ENSG00000127022,ENSG00000081985 |
| REAC:R-HSA-1236975 | Antigen processing-Cross presentation | 0.0063209 | 99 | 480 | 14 | 0.0291667 | 0.1414141 | REAC | ENSG00000204267,ENSG00000092010,ENSG00000179218,ENSG00000231925,ENSG00000100911,ENSG00000170315,ENSG00000167004,ENSG00000204264,ENSG00000166710,ENSG00000163131,ENSG00000204642,ENSG00000204592,ENSG00000172936,ENSG00000041357 |
| REAC:R-HSA-69205 | G1/S-Specific Transcription | 0.0084477 | 28 | 480 | 7 | 0.0145833 | 0.2500000 | REAC | ENSG00000171848,ENSG00000112029,ENSG00000176890,ENSG00000132646,ENSG00000170312,ENSG00000093009,ENSG00000114126 |
| REAC:R-HSA-2555396 | Mitotic Metaphase and Anaphase | 0.0090817 | 196 | 480 | 21 | 0.0437500 | 0.1071429 | REAC | ENSG00000092010,ENSG00000117724,ENSG00000100911,ENSG00000113368,ENSG00000170315,ENSG00000156970,ENSG00000112029,ENSG00000179051,ENSG00000100749,ENSG00000204264,ENSG00000188312,ENSG00000123416,ENSG00000089685,ENSG00000154001,ENSG00000122952,ENSG00000143228,ENSG00000152253,ENSG00000153044,ENSG00000041357,ENSG00000182628,ENSG00000134690 |
| WP:WP619 | Type II interferon signaling (IFNG) | 0.0000097 | 37 | 353 | 13 | 0.0368272 | 0.3513514 | WP | ENSG00000119922,ENSG00000125347,ENSG00000126709,ENSG00000115415,ENSG00000137265,ENSG00000111537,ENSG00000117228,ENSG00000055332,ENSG00000089127,ENSG00000213928,ENSG00000187608,ENSG00000179583,ENSG00000096968 |
| WP:WP4197 | The human immune response to tuberculosis | 0.0000197 | 23 | 353 | 10 | 0.0283286 | 0.4347826 | WP | ENSG00000125347,ENSG00000115415,ENSG00000119917,ENSG00000204264,ENSG00000185885,ENSG00000157601,ENSG00000089127,ENSG00000185745,ENSG00000213928,ENSG00000096968 |
| WP:WP2328 | Allograft Rejection | 0.0003766 | 88 | 353 | 17 | 0.0481586 | 0.1931818 | WP | ENSG00000100453,ENSG00000179344,ENSG00000196126,ENSG00000163599,ENSG00000115523,ENSG00000117560,ENSG00000115415,ENSG00000223865,ENSG00000231389,ENSG00000111537,ENSG00000232810,ENSG00000180644,ENSG00000123416,ENSG00000156234,ENSG00000204642,ENSG00000204592,ENSG00000242574 |
| WP:WP4217 | Ebola Virus Pathway on Host | 0.0011523 | 128 | 353 | 20 | 0.0566572 | 0.1562500 | WP | ENSG00000179344,ENSG00000196126,ENSG00000072110,ENSG00000135077,ENSG00000115415,ENSG00000223865,ENSG00000231389,ENSG00000196924,ENSG00000150093,ENSG00000130402,ENSG00000215305,ENSG00000055332,ENSG00000067560,ENSG00000185507,ENSG00000204642,ENSG00000204592,ENSG00000070831,ENSG00000075624,ENSG00000242574,ENSG00000140575 |
Terms (genesets) of particular interest were highlighted in red to ease which terms to look at when scrolling down
534 downregulated genesets are returned from GO, KEGG, REAC, and WP.
Finally, all the type I immunity related immune terms I was hoping to see popped up, Interferon-gamma is the key inflammatory cytokine that is activated during type I immunity activation. Type I interferon activation terms are also shown, indicating the greater activation of inflammation in patient C than patient B. T cell activation and antigen presentation, which are necessary to fight the tumor by presenting tumor-associated antigen also popped up. Response to IL-12, a type I immunity cytokine, also popped up. Similar terms appeared in Reactome, KEGG, and WP.
And interestingly, the “PD-1 signaling” and “Cancer immunotherapy by PD-1 blockade” terms popped up at the very bottom. Since we know that this is a comparison between patient B and C, these terms indicate the difference in patients is a huge factor in determining the efficacy of the checkpoint inhibitor.
Overall, this result shows that the immunocheckpoint inhibitor may not be able to turn the tide against cancer in certain patients. There is definitely a patient specific bias in the type I immunity response.
Non-Thresholded Analysis
Methods & Genesets
What method did you use?
I have used Gene Set Enrichment Analysis developed by researchers in Broad Institute, because it is the most cited method in terms of non-thresholded analysis as of March 24th 2020. It also has a Java GUI that serves as the go-to tool for most wet-lab researchers when they want to do non-thresholded analysis. pe of analysis.
Also, I liked how the developers of GSEA approached the problem of focusing on handful of genes at the top and bottom of the ranked list.
The problems of these approaches include…
After correcting for multiple hypothesis testing, no individual genes may meet the threshold for statistical significance.
Alternatively, one may be left with a long list of statistically significant genes without unifying biological theme.
Single gene analysis can miss important effect on pathways.
I have first hand experiences with the first 2 points. I did not get any statistically signficant genes after multiple hypothesis correction between treatment cycles. Doing thresholded analysis with long gene lists without multiple hypothesis correction gave me no unifying biological theme, aside from comparing between patients.
I also believe the third point that differential gene expression analysis should focus on the pathway (genesets) differences rather than few genes that are highly differential.
To tackle these problems, GSEA determines whether members of a gene set S tend to occur toward the top or bottom of the ranked gene list, rather than randomly distributed.
What genesets did you use?
I have used a gmt file that is distributed at Dr. Gary Bader’s lab at University of Toronto.
http://baderlab.org/GeneSets
More specifically, I have used “Human_GOBP_AllPathways_no_GO_iea_February_01_2020_symbol.gmt”, which includes the February 2020 human genesets from MsigDB, NCI, Institute of Bioinformatics, Netpath, HumanCyc, Reactome, GO, and Panther.
Enrichment Summary & Comparison to Thresholded Analysis
Running GSEA from the notebook:
Ranked scores of the genes were calculated by sign(log fold change) * -log10(uncorrected p value). GMT file was downloaded and GSEAs are ran here.
# Download February GMT file from bader lab website
gmt_url = "http://download.baderlab.org/EM_Genesets/February_01_2020/Human/symbol/"
#list all the files on the server
filenames = getURL(gmt_url)
tc = textConnection(filenames)
contents = readLines(tc)
close(tc)
#get the gmt that has all the pathways and does not include terms inferred from electronic annotations(IEA)
#start with gmt file that has pathways only
rx = gregexpr("(?<=<a href=\")(.*.GOBP_AllPathways_no_GO_iea.*.)(.gmt)(?=\">)",
contents, perl = TRUE)
gmt_file = unlist(regmatches(contents, rx))
setwd("~")
working_dir <- getwd()
dest_gmt_file <- file.path(working_dir,paste(gmt_file, sep=""))
download.file(
paste(gmt_url,gmt_file,sep=""),
destfile=dest_gmt_file
)##### Fit without function
# Withouts need to be one of those
# "A", "B", "C", "PreTreat", "Cycle1", "Cycle3", "Cycle4"
# Make sure to "Treatment" and "Patient" prefixes to the contrasts
fit.without <- function(expression.matrix, sample.matrix, without, contrasts){
all <- c("A", "B", "C", "PreTreat", "Cycle1", "Cycle3", "Cycle4")
all <- setdiff(all, without)
new_sample.info.matrix <- sample.matrix %>%
filter(str_detect(Treatment, paste(all, collapse="|")) & str_detect(Patient, paste(all, collapse="|")))
new_sample.info.matrix$Patient <- factor(new_sample.info.matrix$Patient)
new_sample.info.matrix$Treatment <- factor(new_sample.info.matrix$Treatment)
# Create the data matrix for linear fit
expression.matrix %>% dplyr::select(new_sample.info.matrix$Label) %>% as.matrix() -> expressionMatrix
rownames(expressionMatrix) <- expression.matrix$ensembl_gene_id
new_minimalSet <- ExpressionSet(assayData=expressionMatrix)
model_design_pat <- model.matrix(~0 + Treatment + Patient , data = new_sample.info.matrix)
# Contrast matrices - tells me what linear regressions contrasts.fit() subtracts to do statistical test between the genes
contrast.matrix <- makeContrasts(contrasts = contrasts,
levels=model_design_pat)
# Making the linear regression models for each gene
fit3 <- lmFit(new_minimalSet, model_design_pat)
fit4 = contrasts.fit(fit3, contrast.matrix)
# trend = TRUE for RNA-seq
fit4 = eBayes(fit4, trend = TRUE)
return(fit4)
}
# One function to do all retrieving of ranked gene list
save.ranked.list.return.file.name <- function(fit, coeff, prefix = ""){
ranked.list <- topTable(fit, number = 17118, adjust.method = "BH",
coef = coeff, p.value = 1)
# Trying to combine the hgnc symbol & external gene name to the this differential results frame
ranked.list %>% rownames_to_column %>%
rename(ensembl_gene_id = rowname) %>%
left_join(y = normalized_counts_annot_final[,1:3], by = "ensembl_gene_id" ) %>%
subset(select=c(1,8,9, 2:7)) -> ranked.list
# Rank
ranked.list <- ranked.list %>%
mutate(rank = sign(logFC)* -log10(P.Value)) %>%
dplyr::select(gene = external_gene_name ,rank)
if(prefix == ""){
file.name <- paste(str_replace(string = coeff, pattern = " - ", replacemen = "_"), "Rank_NO_MHC.rnk", sep = "_")
} else{
file.name <- paste(prefix , str_replace(string = coeff, pattern = " - ", replacemen = "_"), "Rank_NO_MHC.rnk", sep = "_")
}
setwd("~")
directory <- getwd()
write.table(ranked.list, file = file.path(directory, file.name), sep = "\t", row.names = F, quote = F)
return(file.name)
}
# Running GSEA from the notebook
# analysis_name must be
# Cycle4_vs_Cycle3, Cycle3_vs_PreTreat, PatientB_vs_PatientC
run.gsea <- function(rnk_file, analysis_name){
gsea_jar <- "/home/bioc/rstudio/GSEA_4.0.2/gsea-cli.sh"
# java_version <- 11
run_gsea = FALSE
# Checking if ran already
check.if.ran <- paste(analysis_name, ".GseaPreranked", sep = "")
char.dir <- dir()
if(!any(grepl(pattern = check.if.ran, x = char.dir))){
run_gsea = TRUE
}
setwd("~")
working_dir = getwd()
rnk_file = rnk_file
analysis_name = analysis_name
if(run_gsea){
command <- paste( gsea_jar, "GSEAPreRanked -gmx", dest_gmt_file, "-rnk" ,file.path(working_dir,rnk_file),
"-collapse false -nperm 1000 -scoring_scheme weighted -rpt_label ",analysis_name,
"-plot_top_x 120 -rnd_seed 12345 -set_max 200 -set_min 15 -zip_report false -out" ,
working_dir, " > gsea_output.txt",sep=" ")
system(command)
}
}fit.without.PreTreat <- fit.without(contrasts = "PatientB - PatientC", without = "PreTreat",
sample.matrix = sample.info.matrix, expression.matrix =
normalized_counts_annot_final)
fit.without.C <- fit.without(contrasts = "TreatmentCycle3 - TreatmentPreTreat", without = "C",
sample.matrix = sample.info.matrix, expression.matrix =
normalized_counts_annot_final)
Cycle3_Pretreat_rnk <- save.ranked.list.return.file.name(fit2, coeff = "TreatmentCycle3 - TreatmentPreTreat")
No_C_Cycle3_Pretreat_rnk <- save.ranked.list.return.file.name(fit.without.C,
coeff = "TreatmentCycle3 - TreatmentPreTreat",
prefix = "No.C")
# analysis_name must be
# Cycle3_vs_PreTreat
# to prevent rerun over and over again
run.gsea(Cycle3_Pretreat_rnk, "Cycle3_vs_PreTreat")
run.gsea(No_C_Cycle3_Pretreat_rnk, "No.C_Cycle3_vs_PreTreat")
rm( bioconductor_packages, cols, contents, costim.index, filenames, i, IFNG.index, IL12.index, interferon.gamma.index, ltys, PD.1.index, rx, tc, TCR.index, xlim, ylim)Cycle 3 vs Pre-Treat
Summary Statistics
Please do not click on the html links here!
This is just to show an overview of the genesets that have reached statistical significance in the p-value and FDR. As one can see, just 2 genesets passed < 25% FDR, showing the noise of the data.
Enrichment in phenotype: na
- 2330 / 4927 gene sets are upregulated in phenotype na_pos
- 2 gene sets are significant at FDR < 25%
- 76 gene sets are significantly enriched at nominal pvalue < 1%
- 277 gene sets are significantly enriched at nominal pvalue < 5%
- Snapshot of enrichment results
- Detailed enrichment results in html format
- Detailed enrichment results in excel format (tab delimited text)
- Guide to interpret results
Enrichment in phenotype: na
- 2597 / 4927 gene sets are upregulated in phenotype na_neg
- 0 gene sets are significantly enriched at FDR < 25%
- 24 gene sets are significantly enriched at nominal pvalue < 1%
- 112 gene sets are significantly enriched at nominal pvalue < 5%
- Snapshot of enrichment results
- Detailed enrichment results in html format
- Detailed enrichment results in excel format (tab delimited text)
- Guide to interpret results
Dataset details
- The dataset has 17064 features (genes)
- No probe set => gene symbol collapsing was requested, so all 17064 features were used
Gene set details
- Gene set size filters (min=15, max=200) resulted in filtering out 13435 / 18362 gene sets
- The remaining 4927 gene sets were used in the analysis
- List of gene sets used and their sizes (restricted to features in the specified dataset)
Gene markers for the na_pos versus na_neg comparison
- The dataset has 17064 features (genes)
- Detailed rank ordered gene list for all features in the dataset
Global statistics and plots
- Plot of p-values vs. NES
- Global ES histogram
Other
- Parameters used for this analysis
Comments
- There were duplicate row identifiers in the specified ranked list. One id was arbitarilly choosen. Details are below.
Generally, this is OK, but if you want to avoid this automagic, edit your ranked list so that all row ids are unique
# of row ids in original dataset: 17118
# of row UNIQUE ids in original dataset: 17064
# The duplicates were
KBTBD4 Y_RNA Y_RNA PDXDC2P Y_RNA SNORA31 Y_RNA CRIP1 Y_RNA Y_RNA Y_RNA Y_RNA Y_RNA SNORA40 GOLGA7B Y_RNA SRSF8 Y_RNA Y_RNA SNORA58 IDS Y_RNA U3 Y_RNA CRYBG3 Y_RNA KIAA0391 Y_RNA Y_RNA U3 Y_RNA Y_RNA Metazoa_SRP Y_RNA ZNF33B SNORA11 U6 RBL1 SNORA40 Y_RNA Y_RNA SNORA22 POLR2J4 SCARNA18 Y_RNA Y_RNA MIR3615 Y_RNA Y_RNA Y_RNA 7SK SNORD70 Y_RNA U3
Enrichment Results & Comparison
Relatively Upregulated in Treatment Cycle 3 in Peripheral CD8 T cells
# For bringing in notebook ran GSEA pictures
get.4.characteristic.pics <- function(gsea.result, geneset.patterns){
setwd("~")
set.gsea.pic.directory(gsea.result)
pictures <- dir()
indexes <- grepl(pattern = geneset.patterns,
x = pictures)
# include_graphics(pictures[indexes])
p1 <- ggdraw() + draw_image(pictures[indexes][1], scale = 0.99)
p2 <- ggdraw() + draw_image(pictures[indexes][2], scale = 0.99)
p3 <- ggdraw() + draw_image(pictures[indexes][3], scale = 0.99)
p4 <- ggdraw() + draw_image(pictures[indexes][4], scale = 0.99)
plot_grid(p1, p2, p3, p4, nrow = 2, align = "hv")
}
# For bringing in Cytoscape Images
# Must be in Images Directory
get.Cytoscape.Images <- function(name.pattern){
setwd("~/Images")
pictures <- dir()
indexes <- grepl(pattern = name.pattern,
x = pictures)
# include_graphics(pictures[indexes])
p1 <- ggdraw() + draw_image(pictures[indexes][1], scale = 0.99)
plot_grid(p1)
}
get.gsea.table <- function(gsea.result, geneset.patterns, pos.or.neg){
if(pos.or.neg){
pos.or.neg = "gsea_report_for_na_pos"
} else{
pos.or.neg = "gsea_report_for_na_neg"
}
setwd("~")
set.gsea.pic.directory(gsea.result)
directory <- dir()
index <- grepl(pattern = pos.or.neg,
x = directory)
directory = directory[index]
directory = grep(pattern = "xls", x = directory, value = TRUE)
table <- read.csv(file = directory, sep = "\t")
table %>% dplyr::select(c(1,6:8)) %>%
filter(str_detect(NAME, geneset.patterns)) -> table
return(table)
}patterns <- "(?i)enplot_Cross-presentation|(?i)enplot_Regulation_of_runx3_Expression|(?i)enplot_Antiviral_mechanism|(?i)enplot_nik"
get.4.characteristic.pics(gsea.result = "Cycle3_vs_PreTreat.GseaPreranked",
geneset.patterns = patterns)
One of the problems GSEA tries to deal with is no unifying biological themes appearing in thresholded analysis. For my analysis, GSEA has successfully dealt with this limitation.
While no type I immunity related genesets popped up in the thresholded anlaysis, they popped in this unthresholded analysis of ranked gene list. Antigen presentation and interferon gamma genesets suggest the upregulation of cytotoxic immunity. NF-kB is a classical inflammatory and cell survival related transcription factor. And Runx3 is especially interesting because this is the transcription factor known to drive the naive CD8 T cell towards effector CD8 T and memory CD8 T differentiation (Wang et al. 2018). It is also implicated in the tumor infiltration of CD8 T (Song et al. 2020).
Finally, immune-related genesets popped up in GSEA analysis when no unifying theme of genesets popped up in the thresholded analysis where I looked at just few highly differential genes. This shows the power of ranked whole gene list analysis. I have a very noisy data, and yet GSEA is still able to pick up meaningful signals from it.
patterns <- "(?i)Cross-presentation|(?i)Regulation of runx3 Expression|(?i)^Antiviral mechanism|(?i)nik-->"
get.gsea.table("Cycle3_vs_PreTreat.GseaPreranked", pos.or.neg = TRUE, geneset.patterns = patterns) -> table
kable(table) %>% kable_styling() %>% print() %>% invisible()| NAME | NES | NOM.p.val | FDR.q.val |
|---|---|---|---|
| REGULATION OF RUNX3 EXPRESSION AND ACTIVITY%REACTOME DATABASE ID RELEASE 71%8941858 | 1.583426 | 0.0191781 | 0.6414198 |
| NIK–>NONCANONICAL NF-KB SIGNALING%REACTOME DATABASE ID RELEASE 71%5676590 | 1.562776 | 0.0107817 | 0.6667255 |
| ANTIVIRAL MECHANISM BY IFN-STIMULATED GENES%REACTOME%R-HSA-1169410.3 | 1.562410 | 0.0000000 | 0.6478970 |
| CROSS-PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS (ENDOSOMES)%REACTOME%R-HSA-1236978.1 | 1.530059 | 0.0207254 | 0.6381428 |
Relatively Upregulated in Pre-Treatment in Peripheral CD8 T cells
# Parts of 2 Image Names in regex format
patterns <- "(?i)enplot_positive_regulation_of_interleukin-12|(?i)enplot_positive_regulation_of_interleukin-4|(?i)enplot_positive_regulation_of_cd4-pos|(?i)enplot_regulation_of_t_cell_prolif"
get.4.characteristic.pics(gsea.result = "Cycle3_vs_PreTreat.GseaPreranked",
geneset.patterns = patterns)
Interestingly, both IL-12 and IL-4 were upregulated in pre-treatment, with both around similar enrichment score. This is unexpected because IL-12 corresponds to type I immunity and IL-4 corresponds to type II immunity. Type I corresponds to antiviral/antitumoral immunity and type II corresponds to anti-helminth immunity.
When naive T cells get activated by an antigen presenting cell (APC), they get additional cytokine signals that determine the differentiation fate such as type 1 T helper or type 2 T helper cells.
The crazy part is that IL-4 suppresses type I immunity fate whereas IL-12 suppresses type II immunity fate. Cancer would very much prefer IL-4 secretion than IL-12 for obvious reasons.
There can many reasons why both genesets showed up as upregulated in the pre-treatment. Maybe it is due to patient B having different response to the drug than patient A or C. Maybe IL-12 was relatively upregulated in patient B and IL-4 was relatively upregulated in patient A or C
As for positive regulation of CD4 helper T cells and general T cell proliferation, this is also unexpected as we would expect better T cell proliferation in the break inhibited after-treatment T cells. Or this can be an indication of Th2 cell proliferation, instead of cytotoxic T cell proliferation.
My hypothesis for these two results is that maybe the T cells became overly activated and reached terminal differentiation state compared to the T cells in pre-treatment. Or maybe the cancer has figured out a way after first two treatment cycles to inhibit T cells through a different mechanism.
patterns <- "(?i)positive regulation of interleukin-12|(?i)positive regulation of interleukin-4|(?i)positive regulation of cd4-positive, alpha-beta t cell activation|(?i)^regulation of t cell prolif"
get.gsea.table("Cycle3_vs_PreTreat.GseaPreranked", pos.or.neg = F, geneset.patterns = patterns) -> table
kable(table) %>% kable_styling() %>% print() %>% invisible()| NAME | NES | NOM.p.val | FDR.q.val |
|---|---|---|---|
| POSITIVE REGULATION OF INTERLEUKIN-12 PRODUCTION%GOBP%GO:0032735 | -1.672856 | 0.0051546 | 1.0000000 |
| POSITIVE REGULATION OF INTERLEUKIN-4 PRODUCTION%GOBP%GO:0032753 | -1.631223 | 0.0172414 | 0.8442634 |
| REGULATION OF T CELL PROLIFERATION%GOBP%GO:0042129 | -1.460301 | 0.0153610 | 1.0000000 |
| POSITIVE REGULATION OF CD4-POSITIVE, ALPHA-BETA T CELL ACTIVATION%GOBP%GO:2000516 | -1.441800 | 0.0525424 | 1.0000000 |
Cycle 3 vs Pre-Treatment with Patient A & B without C
Rationale
Heatmap of Patient B vs Patient C Top Hits
# Heatmap for Patient B vs Patient C
output.heatmap(compare.1 = "pt.B", compare.2 = "pt.C", gene.frame = PatientB.vs.PatientC)
So in my prior analysis of thresholded gene list obtained from differential gene expression analysis between Patient B and C, I have realized that expression levels of patient A and C cluster together whereas the expression levels of Patient B go toward the opposite of other two patients.
The above heatmap visualizes this phenomenon.
Follow up analysis with gProfiler on this gene list informed me that the CD8 immune related genesets were relatively enriched in patient C than patient B (Differential Gene & gProfiler -> Thresholded Overrepresentation Analysis using gProfiler).
This got me wondering what genesets that can be activated in the CD8 T cells of non-responding patient B that is causing this lack of response to anti-PD-1 antibody compared to patient C, and potentially patient A.
This is why I have decided to do a non-thresholded differential gene analysis on Cycle 3 vs Pre-Treatment in just patient A and B, without the responding patient C.
Patient A may still be a responder, but because I must have a biological replicate to do the limma-trend differential gene analysis, I have decided to include patient A in this analysis. This would give me a chance to compare the genesets popping up in Cycle 3 vs Pre-Treatment in all patients versus Cycle 3 vs Pre-Treatment in patient A and B without C.
Summary Statistics
Please do not click on the html links here!
This is just to show an overview of the genesets that have reached statistical significance in the p-value and FDR. As one can see, there are a lot more statistically significant genesets compared to Cycle3 vs PreTreatment in all patients.
Enrichment in phenotype: na
- 2478 / 4927 gene sets are upregulated in phenotype na_pos
- 61 gene sets are significant at FDR < 25%
- 125 gene sets are significantly enriched at nominal pvalue < 1%
- 304 gene sets are significantly enriched at nominal pvalue < 5%
- Snapshot of enrichment results
- Detailed enrichment results in html format
- Detailed enrichment results in excel format (tab delimited text)
- Guide to interpret results
Enrichment in phenotype: na
- 2449 / 4927 gene sets are upregulated in phenotype na_neg
- 1 gene sets are significantly enriched at FDR < 25%
- 41 gene sets are significantly enriched at nominal pvalue < 1%
- 132 gene sets are significantly enriched at nominal pvalue < 5%
- Snapshot of enrichment results
- Detailed enrichment results in html format
- Detailed enrichment results in excel format (tab delimited text)
- Guide to interpret results
Dataset details
- The dataset has 17064 features (genes)
- No probe set => gene symbol collapsing was requested, so all 17064 features were used
Gene set details
- Gene set size filters (min=15, max=200) resulted in filtering out 13435 / 18362 gene sets
- The remaining 4927 gene sets were used in the analysis
- List of gene sets used and their sizes (restricted to features in the specified dataset)
Gene markers for the na_pos versus na_neg comparison
- The dataset has 17064 features (genes)
- Detailed rank ordered gene list for all features in the dataset
Global statistics and plots
- Plot of p-values vs. NES
- Global ES histogram
Other
- Parameters used for this analysis
Comments
- There were duplicate row identifiers in the specified ranked list. One id was arbitarilly choosen. Details are below.
Generally, this is OK, but if you want to avoid this automagic, edit your ranked list so that all row ids are unique
# of row ids in original dataset: 17118
# of row UNIQUE ids in original dataset: 17064
# The duplicates were
Y_RNA KBTBD4 Y_RNA Y_RNA Y_RNA SRSF8 ZNF33B Y_RNA Y_RNA Y_RNA SNORA40 Y_RNA U3 SNORA58 KIAA0391 GOLGA7B Y_RNA Y_RNA CRIP1 Y_RNA Y_RNA SNORA22 SNORA31 Y_RNA Y_RNA IDS U6 Y_RNA SNORA11 Y_RNA CRYBG3 U3 Y_RNA PDXDC2P Metazoa_SRP MIR3615 Y_RNA Y_RNA Y_RNA Y_RNA RBL1 Y_RNA SNORA40 Y_RNA Y_RNA Y_RNA POLR2J4 Y_RNA Y_RNA Y_RNA 7SK SNORD70 SCARNA18 U3
Enrichment Results & Comparison
Relatively Upregulated in Treatment Cycle 3 in Peripheral CD8 T cells without Patient C
patterns <- "(?i)enplot_costimulation_by_the|(?i)enplot_PD-1|(?i)enplot_PID_CD8|(?i)enplot_IMMUNOREGULATORY_INTERACTIONS"
get.4.characteristic.pics(gsea.result = "No.C_Cycle3_vs_PreTreat.GseaPreranked",
geneset.patterns = patterns)
This result completely surprised me. CD8 TCR signaling and costimulation of immune co-receptors such as CD28 were detected, but at the same time, PD-1 signaling and immunoregulatory interaction between a lymphoid and a non-lymphoid cell were also detected.
This is a very interesting result, because you do not expect PD-1 signaling to happen in anti-PD-1 antibody treatment in CD8 T cells. This may be due to lots of different reasons. One of the reasons can be that in some patients, anti-PD-1 antibody may not be reaching its targets on immune cells such as T cells. Or maybe there is a compensatory inhibitory pathways for cancer that can mimick the effects of PD1 - PDL1 axis, such as TIM3 - Gal9 axis.
If I had a RNA seq of the corresponding melanoma samples as well, it would have been really interesting to check which immunoinhibitory receptors cancer is expressing in response to various treatment cycles.
patterns <- "(?i)costimulation by the|^PD-1|PID_CD8_TCR_PATHWAY|IMMUNOREGULATORY INTERACTIONS"
get.gsea.table("No.C_Cycle3_vs_PreTreat.GseaPreranked", pos.or.neg = TRUE, geneset.patterns = patterns) -> table
kable(table) %>% kable_styling() %>% print() %>% invisible()| NAME | NES | NOM.p.val | FDR.q.val |
|---|---|---|---|
| PID_CD8_TCR_PATHWAY%MSIGDB_C2%PID_CD8_TCR_PATHWAY | 1.975696 | 0.0000000 | 0.0470317 |
| COSTIMULATION BY THE CD28 FAMILY%REACTOME DATABASE ID RELEASE 71%388841 | 1.680892 | 0.0000000 | 0.2520615 |
| PD-1 SIGNALING%REACTOME%R-HSA-389948.1 | 1.649944 | 0.0117925 | 0.2895173 |
| IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON-LYMPHOID CELL%REACTOME%R-HSA-198933.5 | 1.569437 | 0.0026385 | 0.3590539 |
Relatively Upregulated in Pre-Treatment in Peripheral CD8 T cells with Patient A & B without C
# Parts of 2 Image Names in regex format
patterns <- "(?i)enplot_HALLMARK_TNFA|(?i)enplot_INTRINSIC_APOPTOTIC|(?i)enplot_NEGATIVE_REGULATION_OF_EXECUTION|(?i)enplot_REGULATION_OF_INFLAMMATORY"
get.4.characteristic.pics(gsea.result = "No.C_Cycle3_vs_PreTreat.GseaPreranked",
geneset.patterns = patterns)
For pathways that are relatively upregulated in Pre-Treatment, lots of apoptosis pathways popped up. TNFR and intrinsic apoptosis pathways suggest apoptosis of T cells, but the negative regulation of apoptosis execution step suggests many T cells are still surviving in the pre-treatment. One immune pathway popped up associated with inflammatory response.
patterns <- "(?i)HALLMARK TNFA|(?i)INTRINSIC APOPTOTIC|(?i)NEGATIVE REGULATION OF EXECUTION|(?i)REGULATION OF INFLAMMATORY"
get.gsea.table("No.C_Cycle3_vs_PreTreat.GseaPreranked", pos.or.neg = F, geneset.patterns = patterns) -> table
kable(table) %>% kable_styling() %>% print() %>% invisible()| NAME | NES | NOM.p.val | FDR.q.val |
|---|---|---|---|
| INTRINSIC APOPTOTIC SIGNALING PATHWAY BY P53 CLASS MEDIATOR%GOBP%GO:0072332 | -1.617164 | 0.0067454 | 0.6313105 |
| NEGATIVE REGULATION OF EXECUTION PHASE OF APOPTOSIS%GOBP%GO:1900118 | -1.549009 | 0.0320285 | 0.8106052 |
| REGULATION OF INFLAMMATORY RESPONSE%GOBP%GO:0050727 | -1.494546 | 0.0014599 | 0.9308278 |
| POSITIVE REGULATION OF INFLAMMATORY RESPONSE%GOBP%GO:0050729 | -1.360564 | 0.0720268 | 0.9257355 |
| INTRINSIC APOPTOTIC SIGNALING PATHWAY%GOBP%GO:0097193 | -1.358011 | 0.0266458 | 0.9263546 |
| INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE%GOBP%GO:0008630 | -1.203925 | 0.1767516 | 0.9584386 |
| INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE BY P53 CLASS MEDIATOR%GOBP%GO:0042771 | -1.056786 | 0.3992933 | 1.0000000 |
| REGULATION OF OXIDATIVE STRESS-INDUCED INTRINSIC APOPTOTIC SIGNALING PATHWAY%GOBP%GO:1902175 | -1.055911 | 0.3871528 | 1.0000000 |
Enrichment Map in Cytoscape
Cycle 3 vs Pre-Treat
Screenshot of Initial Network
EnrichmentMap Parameters
There are 135 nodes and 706 edges in this initial network. P-value of 0.011, q-value of 1.0, and similarity coefficient of 0.375 were used to formulate this network.
P-value of 0.011 was chosen because I wanted a network with more stringent p-value of around 0.01. But the IL-4 geneset had a p-value just little above 0.01. Because this is an important immune geneset, I have decided to increase my p-value from 0.01 to 0.011 to include this geneset.
Q-value of 1.0 was chosen, because lowering the q-value to just 0.9 vanishes almost all the blue nodes which correspond to the genesets enriched in pre-treatment. Unfortunately, this dataset is very noisy, due to patient B reacting differently to the drug compared to patient A & C.
The default similarity coefficient of 0.375 was chosen. The higher this threshold, the more stringent the edge formation between the nodes. This is because the edge between two nodes suggest there is a greater than the selected similarity coefficient threshold between the two nodes.
Similarity coefficient is a score to gauge the similarity of the two genesets. It is calculated by (# of intersecting genes/# of union of genes + # of intersecting genes/# of genes in the smaller of the two set) * 0.5.
Annotated Theme Networks
AutoAnnotate Parameters
MCL Cluster algorithm from clusterMaker2 app was used, with the edge attribute being similarity coefficient from EnrichmentMap.
The labels on the cluster were generated using Adjacent Words algorithm from WordCloud app, with max words per label being set to 3, and word adjacency bonus set to 8. The attribute names used were GS_DESCR from EnrichmentMap. Max words per cloud were 250 and min word occurrence was 1.
Cluster cutoff was 1.0.
By using these algorithms, the network of similar nodes were collapsed into a network of similar theme clusters.
Well Connected Cycle 3 Network
Figure 1 Well Connected Upregulated Pathways in Cycle 3 compared to Pre-Treatment After AutoAnnotate
Interpretation
First off, the green highlighted nodes are the GSEA pathways that are mentioned in the Non-Thresholded Analysis section. Three of the 4 highlighted nodes “REGULATION OF RUNX3 EXPRESSION AND ACTIVITY”, “NIK–>NONCANONICAL NF-KB SIGNALING”, and “ANTIVIRAL MECHANISM BY IFN-STIMULATED GENES” appeared in the cluster labelled “hedgehog degradation securin”. “CROSS-PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS” did not appear in the given threshold but similar term “ANTIGEN PROCESSING AND PRESENTATION OF EXOGENEOUS PEPTIDE ANTIGEN” appeared in this analysis, highlighted in green in the singleton cluster.
The unexpected part of this cluster label is that there are literature evidences that hedgehog signaling is required for CD8 T cell cytotoxicity, and indeed many nodes with “hedgehog signaling” label appeared inside this cluster (Roche et al. 2013). And this cluster is very well connected to most of the clusters in the figure, related to cell cycle, protein metabolism related processes, as well as singleton immune clusters such as “processing peptide antigen” or “activation innate immune”.
And even more interestingly, securin appeared as the label on this cluster, and there is a literature stating the potential of securin as a prognostic marker for breast cancer, and securin is overexpressed in the TILs and CD8 T cells (Vihervuori et al. 2019).
Securin is an essential metaphase to anaphase regulator, overexpression of which promote cell proliferation and chromosomal instability cancer, and predict significantly increased breast cancer mortality (Vihervuori et al. 2019).
Interestingly, its overexpression is also associated with CD8 tumor infiltrating lymphocytes, although its exact role in CD8 immunity is unclear, aside from the fact that it promotes proliferation. But this “hedgehog degradation securin” cluster is connected to the “negative cell cycle” cluster. Therefore, there may be other roles securin may have aside from proliferation in CD8 T cells.
The potential of securin in regulating CD8 immunity in ways other than metaphse to anaphase regulator is definitely a novel theme that this analysis has enabled me to probe at.
This result does connect to the original paper in that the anti-PD-1 CD8 T cells are more activated compared to the pre treated CD8 T cells in patients. More importantly, this GSEA result visualized by enrichment map app shows the power of non-thresholded analysis compared to analysis that just look at the few genes at the top and bottom of the list. None of the immune related results showed up in the thresholded analysis.
Singleton Cycle 3 Network
Figure 2 Singleton Upregulated Pathways in Cycle 3 compared to Pre-Treatment After AutoAnnotate
A. Nodes related to protein and vesicles
B. Nodes related to DNA repair
C. Nodes without unifying theme
D. Nodes related to autophagy and wnt signaling
Interpretation
Lots of singleton clusters appeared in the Cycle3 vs Pre-Treat EnrichmentMap analysis. Most of the singleton networks, however, were well defined biological processes, although not very well studied in the context of CD8 T cell activation. I found the association of DNA repair genes quite unexpected, and to my surprise, there was a 2012 Immunity paper highlighting on the activation of DNA repair genes is one of the features distinguishing the CD8 memory T cells from exhausted T cells (Doering et al. 2012). Therefore, this maybe an indication that more memory T cells are generated in response to the anti-PD-1 treatment.
Autophagy was also one of the unexpected themes. Again, to my surprise, there has been a paper presenting the inability of CD8 effector T cells to differentiate into memory CD8 T cells when an autophagy gene ATG7 is knocked out in mice (Puleston et al. 2014). The upregulation of this pathway may brings further support to the generation of memory CD8 T cells after 3 weeks of anti-PD-1 treatment.
For figure 2C, histone lysine demethylation was pretty interesting because this suggests differentiation through the epigenetic change in the cells. And for figure 2A, I was not too sure what to make of these vesicle related pathways in the context of CD8 T cell activation.
Compared to results from thresholded methods, non-thresholded analysis gave me a far more meaningful biological genesets to interpret. The thresholded method only returned genesets from CORUM, most of which were not even useful because there was only one gene present in the thresholded list for the specific protein complex terms of CORUM.
PreTreatment Network
Figure 3 Downregulated Pathways in Cycle 3 compared to Pre-Treatment After AutoAnnotate
A. Nodes related to immunity
B. Nodes related to different signaling pathways
C. Nodes without unifying theme
D. Nodes related to extracellular matrix and vesicle
Interpretation
Here, the two green highlighted nodes refer to “POSITIVE REGULATION OF INTERLEUKIN-12 PRODUCTION” and “POSITIVE REGULATION OF INTERLEUKIN-4 PRODUCTION”.
For the relatively downregulated pathways in cycle 3 or relatively upregulated pathways in pre treatment, immune related modules were particular interesting because as stated in the previous section, IL-4 and IL-12 are two contradicting cytokines. This may be due to patients having different responses.
Two kras signaling single clusters appeared in figure 4B from different databases. Since KRAS’s normal physiological role is to relay the extracellular signal to cell proliferation and differentation, this can be interpreted as CD8 T cell is still getting activated in the pre-treatment.
Although the themes in figure 3C and D were interesting, many of them were genesets relating to different organs other than T cells. But the presence of these genesets may suggest that the genetic module regulating a different organ or type of cell such as neurons may also be utilized in regulating T cells.
“Ruffle organization” has appeared in the thresholded analysis of Cycle 4 vs Cycle 3, in the downregulated geneset. With “Ruffle Organization” appearing in downregulated geneset of Cycle 3 vs Pre-Treatment in the non-thresholded analysis, this may suggest that ruffle may potentially be negatively related to CD8 T cell activation.
Summary/Collapsed Network
Figure 4. Collapsed Network of Cycle 3 vs Pre-Treatment Clusters
A. Pre-Treatment Clusters shown in figure 3
B. Singleton Cycle 3 Clusters shown in figure 2
C. Connected Cycle 3 Clusters shown in figure 1
Interpretation
Here, the labelled collapsed groups of clusters refer to the ones I have interpreted in the context of CD8 T cell biology, which include IL-12 and IL-4, DNA repair & autophagy, and hedgehog & securin.
Major themes in this analysis include CD8 T cell activation module involving hedgehog signalling, Runx3 and securin upregulation, connected to various mRNA processing modules as well as cell cycle related modules. In the singleton clusters, there are DNA repair and autophagy modules enriched in cycle 3 whereas IL-12, IL-4 and KRAS related modules were enriched in pre-treatment.
There are lots of themes that pertain to genes involved in other cell type processes such as neurons and even podocytes. If these genesets are not false positives, then the sharing of these modules across different cell types highlights the importance and versatility of these modules. Careful wet lab researches should be conducted to address these findings.
There are also lots of vesicle and ubiquitination/de-ubiquitination related themes popping up. Ubiquitination has a crucial role in TCR signaling, and thus these themes are expected of CD8 T cells before and after the anti-PD-1 treatment (Hu and Sun 2016). Vesicles as well, has well defined roles in CD8 T effector function in transporting effector molecules such as perforin and granzymes.
Dark Matter Analysis
Because I am interested in probing what potential new genes may be involved in CD8 T cell biology as well as how many of my significant genes contributed to my GSEA analysis, I have decided to look at the genetic dark matters of my Cycle 3 vs Pre-Treatment. Below is the significant differential gene results of Cycle 3 vs Pre-Treatment by limma-trend analysis without multiple hypothesis correction.
summary(decideTests(fit2, adjust.method = "none")) %>% as.data.frame() %>%
dcast(Var1 ~ Var2, value.var = "Freq") %>% arrange(-row_number()) %>%
dplyr::select(c(1, 3)) -> try
kable(try) %>%
kable_styling(bootstrap_options = "striped", full_width = F)| Var1 | TreatmentCycle3 - TreatmentPreTreat |
|---|---|
| Up | 161 |
| NotSig | 16731 |
| Down | 226 |
The above table shows how many genes are in each of the gene sets used in the Cycle 3 vs Pre-Treatment analysis.
# Venn Diagram of Dark Matter Overlaps
library(VennDiagram)
A <- genes_all_gs
B <- genes_enr_gs
C <- unique(expression[,1])
setwd("~")
grid::grid.newpage()
invisible(draw.triple.venn( area1=length(A), area2=length(B), area3 = length(C),
n12 = length(intersect(A,B)), n13=length(intersect(A,C)),
n23 = length(intersect(B,C)),
n123 = length(intersect(A,intersect(B,C))),
category = c("all genesets","all enrichment results","expression"),
fill = c("red","green","blue"),
cat.col = c("red","green","blue")
))
6685 genes were not annotated to any of the genesets in the GMT file, which are the genetic dark matters that have no annotations.
2565 genes were annotated to the genesets but were not significantly enriched. Some of these genes may not have been in enrichment results because the functions they were annotated to get filtered out due to their large or small size.
7814 genes were annotated to the enriched genesets. Surprisingly, 5067 genes from enriched genesets were not in the original expression matrix.
1030 genes in the genesets were not in the original expression matrix.
Heatmap of Significant Genes Not Annotated to any Pathways Returned in the Enrichment Analysis
# Set of genes that have no annotations from any of the pathways returned in the enrichment analysis
genes_no_annotation_er <- setdiff(unique(expression[,1]), genes_sig_enr_gs)
# Set of genes that have no annotations from entire set of pathways used for the analysis)
genes_no_annotation <- setdiff(unique(expression[,1]), genes_all_gs)
# Top ranked genes that have no annotations
ranked_gene_no_annotation <- ranks[which(ranks[,1] %in% genes_no_annotation),]
# ranked_gene_no_annotation %>% View()
Cycle3.vs.PreTreat[which(Cycle3.vs.PreTreat$external_gene_name %in% genes_no_annotation),] %>%
distinct(external_gene_name, .keep_all = TRUE) -> sig_genes_no_annotation
Cycle3.vs.PreTreat[which(Cycle3.vs.PreTreat$external_gene_name %in% genes_no_annotation_er),] %>%
distinct(external_gene_name, .keep_all = TRUE) -> sig_genes_no_annotation_er
nrow(sig_genes_no_annotation_er)## [1] 322
There were 334 significant genes not annotated to enriched pathway, which was shocking to me, when there were 161 + 226 = 387 significant genes. Interestingly, those 334 genes only really clustered around pre-treatment and cycle 3.
Heatmap of Significant Genes Not Annotated to any Pathways in Entire Set of Pathways Used for the Analysis
## [1] 188
There were 188 significant genes not annotated to whole genesets in the GMT, again a shocking to me, when there are 161 + 226 = 387 significant genes. Again, those 188 genes only really clustered around pre-treatment and cycle 3.
Interpretation
With Regards to Original Paper
Do the enrichment results support conclusions or mechanism discussed in the original paper? How do these results differ from the results you got from Assignment #2 thresholded methods
The enrichment results do support the conclusions discussed in the original paper.
One of the conclusions stated in the paper was that the T cell activation genesets or Mki67 correlates appeared in the leading edge of upregulated geneset when compared with pre treatment samples. (Huang et al. 2017) My non-thresholded result does clearly show this point as genesets related to hedgehog pathway, Runx3 expression appeared in my GSEA results between cycle 3 and pretreatment.
The paper also stated the involvement of other parameters such as anatomical location of metastases, PD-L1 expression, and mutational phenotype add further resolution to how anti-PD-1 treatment can respond in different patients. (Huang et al. 2017; Sun et al. 2020) These factors may explain why “PD-1 signaling” term appeared in the upregulated geneset between cycle 3 and pretreatment without the treatment responding patient B.
These conclusions indicate that although immunocheckpoint inhibitors have been successful to garner prestigous awards like Nobel prize, there are still lots of research we can do to improve the therapy.
Compared to assignment #2, lots of immune related genesets popped up between cycle 3 and pre-treatment, when none has appeared in thresholded results. This shows the power of whole ranked gene list analysis compared to just focusing on the top and bottom of the ranked gene list.
Evidences Supporting My Result
Can you find evidence, i.e. publications, to support some of the results that you see? How does this evidence support your results?
There are lots of evidences supporting my results. Runx3, hedgehog signaling, autophagy, DNA repair, securin, are known pathways that promote or directly involved in CD8 T cell activation and memory phase differentiation (Puleston et al. 2014; Doering et al. 2012; Vihervuori et al. 2019; Song et al. 2020; Roche et al. 2013). The fact that these pathways are popping up in my non-thresholded analysis shows that compared to pre-treatment, CD8 T cells after 3 cycles of treatment are better equipped to fight off melanoma.
Moreover, my Cycle 3 vs Pre-Treatment without Patient C result suggests that PD-1 signaling may still be active in certain patients even after pembrolizumab treatment. Although it is not entirely clear why would this be the case, there are lots of papers that try to explain the different responses of this therapy in different patients, and one of the mechanisms is the anatomical location of metastases (Sun et al. 2020). Maybe pembrolizumab do not reach far enough to inhibit PD-1 signaling in all T cells.
Overall non-thresholded analysis was a very fruitful experience!
References
Chen, Hanbo, and Paul C Boutros. 2011. “VennDiagram: A Package for the Generation of Highly-Customizable Venn and Euler Diagrams in R.” BMC Bioinformatics 12 (1). BioMed Central: 35.
Doering, Travis A, Alison Crawford, Jill M Angelosanto, Michael A Paley, Carly G Ziegler, and E John Wherry. 2012. “Network Analysis Reveals Centrally Connected Genes and Pathways Involved in Cd8+ T Cell Exhaustion Versus Memory.” Immunity 37 (6). Elsevier: 1130–44.
Gu, Zuguang, Roland Eils, and Matthias Schlesner. 2016. “Complex Heatmaps Reveal Patterns and Correlations in Multidimensional Genomic Data.” Bioinformatics 32 (18). Oxford University Press: 2847–9.
Hu, Hongbo, and Shao-Cong Sun. 2016. “Ubiquitin Signaling in Immune Responses.” Cell Research 26 (4). Nature Publishing Group: 457–83.
Huang, Alexander C, Michael A Postow, Robert J Orlowski, Rosemarie Mick, Bertram Bengsch, Sasikanth Manne, Wei Xu, et al. 2017. “T-Cell Invigoration to Tumour Burden Ratio Associated with Anti-Pd-1 Response.” Nature 545 (7652). Nature Publishing Group: 60.
Isserlin, Ruth, Daniele Merico, Veronique Voisin, and Gary D Bader. 2014. “Enrichment Map–a Cytoscape App to Visualize and Explore Omics Pathway Enrichment Results.” F1000Research 3. Faculty of 1000 Ltd.
Kucera, Mike, Ruth Isserlin, Arkady Arkhangorodsky, and Gary D Bader. 2016. “AutoAnnotate: A Cytoscape App for Summarizing Networks with Semantic Annotations.” F1000Research 5. Faculty of 1000 Ltd.
Morris, John H, Leonard Apeltsin, Aaron M Newman, Jan Baumbach, Tobias Wittkop, Gang Su, Gary D Bader, and Thomas E Ferrin. 2011. “ClusterMaker: A Multi-Algorithm Clustering Plugin for Cytoscape.” BMC Bioinformatics 12 (1). Springer: 436.
Oesper, Layla, Daniele Merico, Ruth Isserlin, and Gary D Bader. 2011. “WordCloud: A Cytoscape Plugin to Create a Visual Semantic Summary of Networks.” Source Code for Biology and Medicine 6 (1). Springer: 7.
Otasek, David, John H Morris, Jorge Bouças, Alexander R Pico, and Barry Demchak. 2019. “Cytoscape Automation: Empowering Workflow-Based Network Analysis.” Genome Biology 20 (1). BioMed Central: 1–15.
Puleston, Daniel J, Hanlin Zhang, Timothy J Powell, Elina Lipina, Stuart Sims, Isabel Panse, Alexander S Watson, et al. 2014. “Autophagy Is a Critical Regulator of Memory Cd8+ T Cell Formation.” Elife 3. eLife Sciences Publications Limited: e03706.
Raudvere, Uku, Liis Kolberg, Ivan Kuzmin, Tambet Arak, Priit Adler, Hedi Peterson, and Jaak Vilo. 2019. “G: Profiler: A Web Server for Functional Enrichment Analysis and Conversions of Gene Lists (2019 Update).” Nucleic Acids Research 47 (W1). Oxford University Press: W191–W198.
Ritchie, Matthew E, Belinda Phipson, DI Wu, Yifang Hu, Charity W Law, Wei Shi, and Gordon K Smyth. 2015. “Limma Powers Differential Expression Analyses for Rna-Sequencing and Microarray Studies.” Nucleic Acids Research 43 (7). Oxford University Press: e47–e47.
Robinson, Mark D, and Alicia Oshlack. 2010. “A Scaling Normalization Method for Differential Expression Analysis of Rna-Seq Data.” Genome Biology 11 (3). BioMed Central: R25.
Robinson, M D, D J McCarthy, and G K Smyth. 2010. “EdgeR: A Bioconductor Package for Differential Expression Analysis of Digital Gene Expression Data.” Bioinformatics 26 (1): 139–40. https://doi.org/10.1093/bioinformatics/btp616.
Roche, Maike de la, Alex T Ritter, Karen L Angus, Colin Dinsmore, Charles H Earnshaw, Jeremy F Reiter, and Gillian M Griffiths. 2013. “Hedgehog Signaling Controls T Cell Killing at the Immunological Synapse.” Science 342 (6163). American Association for the Advancement of Science: 1247–50.
Song, Qian, Jun Shang, Chufan Zhang, Jianing Chen, Lanlin Zhang, and Xianghua Wu. 2020. “Transcription Factor Runx3 Promotes Cd8+ T Cell Recruitment by Ccl3 and Ccl20 in Lung Adenocarcinoma Immune Microenvironment.” Journal of Cellular Biochemistry. Wiley Online Library.
Sun, Leitao, Leyin Zhang, Jieru Yu, Yinan Zhang, Xi Pang, Chenghao Ma, Minhe Shen, Shanming Ruan, Harpreet S Wasan, and Shengliang Qiu. 2020. “Clinical Efficacy and Safety of Anti-Pd-1/Pd-L1 Inhibitors for the Treatment of Advanced or Metastatic Cancer: A Systematic Review and Meta-Analysis.” Scientific Reports 10 (1). Nature Publishing Group: 1–13.
Vihervuori, H, TA Autere, H Repo, S Kurki, L Kallio, MM Lintunen, K Talvinen, and P Kronqvist. 2019. “Tumor-Infiltrating Lymphocytes and Cd8+ T Cells Predict Survival of Triple-Negative Breast Cancer.” Journal of Cancer Research and Clinical Oncology 145 (12). Springer: 3105–14.
Wang, Dapeng, Huitian Diao, Adam J Getzler, Walter Rogal, Megan A Frederick, Justin Milner, Bingfei Yu, Shane Crotty, Ananda W Goldrath, and Matthew E Pipkin. 2018. “The Transcription Factor Runx3 Establishes Chromatin Accessibility of Cis-Regulatory Landscapes That Drive Memory Cytotoxic T Lymphocyte Formation.” Immunity 48 (4). Elsevier: 659–74.
n.d. RP11 BAC Clones. https://empiregenomics.com/catalog/rp11-bac-clones?p=595.